myocyte-specific enhancer factor 2C isoform X5 [Macaca mulatta]
myocyte-specific enhancer factor 2( domain architecture ID 10083624)
myocyte-specific enhancer factor 2 (MEF2) is a MADS (MCM1, AGAMOUS, DEFICIENS, and SRF, serum response factor) domain transcription factor, such as human MEF2C, a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes
List of domain hits
Name | Accession | Description | Interval | E-value | ||
MADS_MEF2_like | cd00265 | MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ... |
2-78 | 5.03e-40 | ||
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi. : Pssm-ID: 238165 [Multi-domain] Cd Length: 77 Bit Score: 137.68 E-value: 5.03e-40
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HJURP_C super family | cl13744 | Holliday junction regulator protein family C-terminal repeat; Although this family is ... |
107-155 | 2.41e-10 | ||
Holliday junction regulator protein family C-terminal repeat; Although this family is conserved in the Holliday junction regulator, HJURP, proteins in higher eukaryotes, alongside an Scm3, pfam10384, family, its exact function is not known. The C-terminal region of Scm3 proteins has been evolving rapidly, and this short repeat at the C-terminal end can be present in up to two copies in the higher eukaryotes. The actual alignment was detected with superfamily member pfam12347: Pssm-ID: 463543 Cd Length: 63 Bit Score: 56.20 E-value: 2.41e-10
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Name | Accession | Description | Interval | E-value | |||||
MADS_MEF2_like | cd00265 | MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ... |
2-78 | 5.03e-40 | |||||
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi. Pssm-ID: 238165 [Multi-domain] Cd Length: 77 Bit Score: 137.68 E-value: 5.03e-40
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MADS | smart00432 | MADS domain; |
2-60 | 1.23e-32 | |||||
MADS domain; Pssm-ID: 197721 [Multi-domain] Cd Length: 59 Bit Score: 117.66 E-value: 1.23e-32
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SRF-TF | pfam00319 | SRF-type transcription factor (DNA-binding and dimerization domain); |
10-57 | 1.07e-24 | |||||
SRF-type transcription factor (DNA-binding and dimerization domain); Pssm-ID: 459760 [Multi-domain] Cd Length: 48 Bit Score: 95.96 E-value: 1.07e-24
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HJURP_C | pfam12347 | Holliday junction regulator protein family C-terminal repeat; Although this family is ... |
107-155 | 2.41e-10 | |||||
Holliday junction regulator protein family C-terminal repeat; Although this family is conserved in the Holliday junction regulator, HJURP, proteins in higher eukaryotes, alongside an Scm3, pfam10384, family, its exact function is not known. The C-terminal region of Scm3 proteins has been evolving rapidly, and this short repeat at the C-terminal end can be present in up to two copies in the higher eukaryotes. Pssm-ID: 463543 Cd Length: 63 Bit Score: 56.20 E-value: 2.41e-10
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ARG80 | COG5068 | Regulator of arginine metabolism and related MADS box-containing transcription factors ... |
1-245 | 4.24e-10 | |||||
Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]; Pssm-ID: 227400 [Multi-domain] Cd Length: 412 Bit Score: 61.18 E-value: 4.24e-10
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Name | Accession | Description | Interval | E-value | |||||
MADS_MEF2_like | cd00265 | MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ... |
2-78 | 5.03e-40 | |||||
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi. Pssm-ID: 238165 [Multi-domain] Cd Length: 77 Bit Score: 137.68 E-value: 5.03e-40
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MADS | smart00432 | MADS domain; |
2-60 | 1.23e-32 | |||||
MADS domain; Pssm-ID: 197721 [Multi-domain] Cd Length: 59 Bit Score: 117.66 E-value: 1.23e-32
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MADS | cd00120 | MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic ... |
2-60 | 1.15e-29 | |||||
MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type II. These subgroups differ mainly in position of the alpha 2 helix responsible for the dimerization interface; Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi. Pssm-ID: 238067 [Multi-domain] Cd Length: 59 Bit Score: 109.53 E-value: 1.15e-29
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MADS_SRF_like | cd00266 | SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ... |
2-83 | 1.71e-26 | |||||
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi. Pssm-ID: 238166 [Multi-domain] Cd Length: 83 Bit Score: 101.95 E-value: 1.71e-26
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SRF-TF | pfam00319 | SRF-type transcription factor (DNA-binding and dimerization domain); |
10-57 | 1.07e-24 | |||||
SRF-type transcription factor (DNA-binding and dimerization domain); Pssm-ID: 459760 [Multi-domain] Cd Length: 48 Bit Score: 95.96 E-value: 1.07e-24
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HJURP_C | pfam12347 | Holliday junction regulator protein family C-terminal repeat; Although this family is ... |
107-155 | 2.41e-10 | |||||
Holliday junction regulator protein family C-terminal repeat; Although this family is conserved in the Holliday junction regulator, HJURP, proteins in higher eukaryotes, alongside an Scm3, pfam10384, family, its exact function is not known. The C-terminal region of Scm3 proteins has been evolving rapidly, and this short repeat at the C-terminal end can be present in up to two copies in the higher eukaryotes. Pssm-ID: 463543 Cd Length: 63 Bit Score: 56.20 E-value: 2.41e-10
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ARG80 | COG5068 | Regulator of arginine metabolism and related MADS box-containing transcription factors ... |
1-245 | 4.24e-10 | |||||
Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]; Pssm-ID: 227400 [Multi-domain] Cd Length: 412 Bit Score: 61.18 E-value: 4.24e-10
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Blast search parameters | ||||
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