|
Name |
Accession |
Description |
Interval |
E-value |
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
49-249 |
2.77e-45 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 165.13 E-value: 2.77e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 49 FHLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQ 128
Cdd:COG0666 58 LLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVK 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 129 ILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDS 208
Cdd:COG0666 138 LLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDN 217
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 966946461 209 LGHNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHD 249
Cdd:COG0666 218 DGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLL 258
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
49-240 |
1.29e-44 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 163.20 E-value: 1.29e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 49 FHLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQ 128
Cdd:COG0666 91 LHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVK 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 129 ILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDS 208
Cdd:COG0666 171 LLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDK 250
|
170 180 190
....*....|....*....|....*....|..
gi 966946461 209 LGHNALHYSKLSENAGIQSLLLSKISQDADLK 240
Cdd:COG0666 251 DGLTALLLAAAAGAALIVKLLLLALLLLAAAL 282
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
49-244 |
5.68e-36 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 138.16 E-value: 5.68e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 49 FHLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQ 128
Cdd:COG0666 25 LLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVK 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 129 ILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDS 208
Cdd:COG0666 105 LLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDN 184
|
170 180 190
....*....|....*....|....*....|....*.
gi 966946461 209 LGHNALHYSKLSENAGIQSLLLSKisqDADLKTPTK 244
Cdd:COG0666 185 DGETPLHLAAENGHLEIVKLLLEA---GADVNAKDN 217
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
50-214 |
5.84e-34 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 132.39 E-value: 5.84e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 50 HLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQI 129
Cdd:COG0666 125 HLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKL 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 130 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDSL 209
Cdd:COG0666 205 LLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLD 284
|
....*
gi 966946461 210 GHNAL 214
Cdd:COG0666 285 LLTLL 289
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
70-242 |
1.35e-25 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 108.12 E-value: 1.35e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 70 DVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLL 149
Cdd:COG0666 13 AALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLH 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 150 LAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDSLGHNALHYSKLSENAGIQSLL 229
Cdd:COG0666 93 AAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLL 172
|
170
....*....|....*..
gi 966946461 230 LSK----ISQDADLKTP 242
Cdd:COG0666 173 LEAgadvNARDNDGETP 189
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
82-174 |
2.08e-23 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 95.18 E-value: 2.08e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 82 LHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKsPINLKDlDGNIPLLLAVQNGHSEICH 161
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHA-DVNLKD-NGRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 966946461 162 FLLDHGADVNSRN 174
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
115-207 |
1.20e-22 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 92.87 E-value: 1.20e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 115 LHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHgADVNSRNKsGRTALMLACEIGSSNVVE 194
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 966946461 195 ALIKKGADLNLVD 207
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
49-141 |
6.07e-22 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 90.95 E-value: 6.07e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 49 FHLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQsKCPAESVDsSGKTALHYAAAQGCLQAVQ 128
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLE-HADVNLKD-NGRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 966946461 129 ILCEHKSPINLKD 141
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
49-181 |
2.22e-21 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 95.41 E-value: 2.22e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 49 FHLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQ 128
Cdd:COG0666 157 LHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVK 236
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 966946461 129 ILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTAL 181
Cdd:COG0666 237 LLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
58-231 |
6.97e-18 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 87.41 E-value: 6.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 58 VECLRVMVTHGVDVTAQDTTGHSALHLAAKNS--HHECIRKLLQSKCPAESVDSSGKTALHYAAAQGC--LQAVQILCEH 133
Cdd:PHA03100 86 KEIVKLLLEYGANVNAPDNNGITPLLYAISKKsnSYSIVEYLLDNGANVNIKNSDGENLLHLYLESNKidLKILKLLIDK 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 134 KSPINLKDldgNIPLLLavqnghseichfllDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDSLGHNA 213
Cdd:PHA03100 166 GVDINAKN---RVNYLL--------------SYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTP 228
|
170
....*....|....*...
gi 966946461 214 LHYSKLSENAGIQSLLLS 231
Cdd:PHA03100 229 LHIAILNNNKEIFKLLLN 246
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
148-232 |
5.24e-17 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 77.08 E-value: 5.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 148 LLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKgADLNLVDSlGHNALHYSKLSENAGIQS 227
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVK 78
|
....*
gi 966946461 228 LLLSK 232
Cdd:pfam12796 79 LLLEK 83
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
49-206 |
3.53e-16 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 81.96 E-value: 3.53e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 49 FHLAAAKGHV---ECLRVMVTHGVDVTAQDttGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQ 125
Cdd:PHA02875 72 LHDAVEEGDVkavEELLDLGKFADDVFYKD--GMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIK 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 126 AVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALM-LACEIGSSNVVEALIKKGADLN 204
Cdd:PHA02875 150 GIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAALcYAIENNKIDIVRLFIKRGADCN 229
|
..
gi 966946461 205 LV 206
Cdd:PHA02875 230 IM 231
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
422-938 |
4.39e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 83.19 E-value: 4.39e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELvclnnteisENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKlg 501
Cdd:PRK03918 187 RTENIEELIKEKEKELEEVLREINEISSELPELREEL---------EKLEKEVKELEELKEEIEELEKELESLEGSKR-- 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 502 lvspesmdnyshlhelrvteeeinVLKQDLQNALEESERNKEKVRELEEKLVEREKgtvIKPPVEEYEEMK---SSYCSV 578
Cdd:PRK03918 256 ------------------------KLEEKIRELEERIEELKKEIEELEEKVKELKE---LKEKAEEYIKLSefyEEYLDE 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 579 IENMNKEKAFLFEKYQEAQEEIMKLKDtlKSQMTQEASDEAEDMKEAMNRMidelnKQVSELSQLYKEAQAELEDYRKRk 658
Cdd:PRK03918 309 LREIEKRLSRLEEEINGIEERIKELEE--KEERLEELKKKLKELEKRLEEL-----EERHELYEEAKAKKEELERLKKR- 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 659 sledITAEYIHKAEHEklmqLTNVSRAKAE--DALSEMKSQYSKVLNELTQLKQLVDAQKENSVS-------ITEH--LQ 727
Cdd:PRK03918 381 ----LTGLTPEKLEKE----LEELEKAKEEieEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgreLTEEhrKE 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 728 VITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDamvpRSSYEKLQSSLESEVSVLASKLKESVKEKE 807
Cdd:PRK03918 453 LLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL----KELAEQLKELEEKLKKYNLEELEKKAEEYE 528
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 808 KVHSEVAQIRSEVSQVKREKENIQTLLKSKEqevnELLQKFQQAQEELAEM-KRYSESSSKLEEDKDKKINEMSKEVTKL 886
Cdd:PRK03918 529 KLKEKLIKLKGEIKSLKKELEKLEELKKKLA----ELEKKLDELEEELAELlKELEELGFESVEELEERLKELEPFYNEY 604
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 966946461 887 KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKHHQEVISVY 938
Cdd:PRK03918 605 LELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY 656
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
516-886 |
1.68e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 81.64 E-value: 1.68e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 516 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI-KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQ 594
Cdd:TIGR02168 692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARlEAEVEQLEERIAQLSKELTELEAEIEELEERLE 771
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 595 EAQEEIMKLKDTLKSQmtQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDITAEYIH--KAE 672
Cdd:TIGR02168 772 EAEEELAEAEAEIEEL--EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEeqIEE 849
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 673 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQvitTLRTAAKEMEEKISNLKEHLAS 752
Cdd:TIGR02168 850 LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR---ELESKRSELRRELEELREKLAQ 926
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 753 KEVEVAKLEKQLLEekaamtdamvprssyekLQSSLESEVSVLaskLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQt 832
Cdd:TIGR02168 927 LELRLEGLEVRIDN-----------------LQERLSEEYSLT---LEEAEALENKIEDDEEEARRRLKRLENKIKELG- 985
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 966946461 833 llkskeqEVNEL-LQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKEVTKL 886
Cdd:TIGR02168 986 -------PVNLAaIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
41-214 |
7.92e-15 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 78.08 E-value: 7.92e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 41 RPRKLKHCFHLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAA 120
Cdd:PHA02874 120 KDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAE 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 121 QGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEIChfLLDHGADVNSRNKSGRTALMLA----CEIgssNVVEAL 196
Cdd:PHA02874 200 YGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIIHNRSAIE--LLINNASINDQDIDGSTPLHHAinppCDI---DIIDIL 274
|
170
....*....|....*...
gi 966946461 197 IKKGADLNLVDSLGHNAL 214
Cdd:PHA02874 275 LYHKADISIKDNKGENPI 292
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
94-238 |
5.14e-14 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 75.45 E-value: 5.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 94 IRKLLQSKCPAESVDSSGKTALHY---AAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSE-ICHFLLDHGAD 169
Cdd:PHA03095 30 VRRLLAAGADVNFRGEYGKTPLHLylhYSSEKVKDIVRLLLEAGADVNAPERCGFTPLHLYLYNATTLdVIKLLIKAGAD 109
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966946461 170 VNSRNKSGRTALMlACEIGSS---NVVEALIKKGADLNLVDSLGHNALHYSKLSENAGIQ--SLLLSKISQDAD 238
Cdd:PHA03095 110 VNAKDKVGRTPLH-VYLSGFNinpKVIRLLLRKGADVNALDLYGMTPLAVLLKSRNANVEllRLLIDAGADVYA 182
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
422-936 |
1.15e-13 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 75.49 E-value: 1.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELvclnnteisenssdlsQKLKETQSKYEEAMKEVLSVQKQMKLG 501
Cdd:PRK03918 232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERI----------------EELKKEIEELEEKVKELKELKEKAEEY 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 502 LVSPESMDNY-SHLHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVE-REKGTVIKPPVEEYEEMKSsycsVI 579
Cdd:PRK03918 296 IKLSEFYEEYlDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKElEKRLEELEERHELYEEAKA----KK 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 580 ENMNKEKAflfekyQEAQEEIMKLKDTLKsqmtqeasdEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKS 659
Cdd:PRK03918 372 EELERLKK------RLTGLTPEKLEKELE---------ELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKG 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 660 LEDITAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEnsvsitehlqvITTLRTAAKEM 739
Cdd:PRK03918 437 KCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE-----------LIKLKELAEQL 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 740 EEKISNLKEHLAsKEVEVAKLEKQLLEEKAAmtdamvprsSYEKLQSSLESEVSvlasKLKESVKEKEKVHSEVAQIRSE 819
Cdd:PRK03918 506 KELEEKLKKYNL-EELEKKAEEYEKLKEKLI---------KLKGEIKSLKKELE----KLEELKKKLAELEKKLDELEEE 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 820 VSQVKREKENI----QTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 895
Cdd:PRK03918 572 LAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 966946461 896 LSYS--TSSSKRQSQQLEALQQQVKQLQNQLAECKKHHQEVIS 936
Cdd:PRK03918 652 LEKKysEEEYEELREEYLELSRELAGLRAELEELEKRREEIKK 694
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
58-216 |
1.68e-13 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 73.91 E-value: 1.68e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 58 VECLRVMVTHGVDVTAQDTTGHSALHLAAKNSH--HECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQI--LCEH 133
Cdd:PHA03095 167 VELLRLLIDAGADVYAVDDRFRSLLHHHLQSFKprARIVRELIRAGCDPAATDMLGNTPLHSMATGSSCKRSLVlpLLIA 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 134 KSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDslghNA 213
Cdd:PHA03095 247 GISINARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMVRNNNGRAVRAALAKNPSAETVA----AT 322
|
...
gi 966946461 214 LHY 216
Cdd:PHA03095 323 LNT 325
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
308-891 |
5.77e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 73.18 E-value: 5.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 308 ISSIRENKDRLSDSTTGA---DSLLDISSEADQQDLLALLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHSTQT 384
Cdd:TIGR02169 193 IDEKRQQLERLRREREKAeryQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 385 DLgpslgkpgETSPPDSKSSPPVLIHALGKSTTDSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNnT 464
Cdd:TIGR02169 273 LL--------EELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE-R 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 465 EISENSSD---LSQKLKETQSKYEEAMKEVLSVQKqmKLGLVSPESMDNYSHLHELRvteEEINVLKQDLQNALEESERN 541
Cdd:TIGR02169 344 EIEEERKRrdkLTEEYAELKEELEDLRAELEEVDK--EFAETRDELKDYREKLEKLK---REINELKRELDRLQEELQRL 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 542 KEKVRELEEKLverekgTVIKPPVEEYEEMKssycsvienmnKEKAflfEKYQEAQEEIMKLKDTLKSqmtqeASDEAED 621
Cdd:TIGR02169 419 SEELADLNAAI------AGIEAKINELEEEK-----------EDKA---LEIKKQEWKLEQLAADLSK-----YEQELYD 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 622 MKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDITAEYIhKAEHEKLMQLTNVSRAKA-------------- 687
Cdd:TIGR02169 474 LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASI-QGVHGTVAQLGSVGERYAtaievaagnrlnnv 552
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 688 ---EDALSEMKSQYSKV----------LNELTQLKQLVDAQKENSVsITEHLQVIttlrtaakEMEEKISN-----LKEH 749
Cdd:TIGR02169 553 vveDDAVAKEAIELLKRrkagratflpLNKMRDERRDLSILSEDGV-IGFAVDLV--------EFDPKYEPafkyvFGDT 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 750 LASKEVEVAK----------LEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSE 819
Cdd:TIGR02169 624 LVVEDIEAARrlmgkyrmvtLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966946461 820 VSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY-SESSSKLEEDK------DKKINEMSKEVTKLKEALN 891
Cdd:TIGR02169 704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDlSSLEQEIENVKselkelEARIEELEEDLHKLEEALN 782
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
422-926 |
6.71e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 73.05 E-value: 6.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELvclnnTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLG 501
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAEL-----EELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 502 LVspESMDNYSHLHELrvtEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGtvikppVEEYEEMKSSYCSVIEN 581
Cdd:COG1196 308 EE--RRRELEERLEEL---EEELAELEEELEELEEELEELEEELEEAEEELEEAEAE------LAEAEEALLEAEAELAE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 582 MNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDmkEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKR--KS 659
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL--ERLEEELEELEEALAELEEEEEEEEEALEEAAEEeaEL 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 660 LEDITAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQ---------LKQLVDAQKENSVSITEHLQVIT 730
Cdd:COG1196 455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADyegflegvkAALLLAGLRGLAGAVAVLIGVEA 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 731 TLRTAAkemEEKISNLKEHLASKEVEVAKLEKQLLEEKAA-------MTDAMVPRSSYEKLQSSLESEVSVLASKLKESV 803
Cdd:COG1196 535 AYEAAL---EAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratflpLDKIRARAALAAALARGAIGAAVDLVASDLREA 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 804 KEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKEV 883
Cdd:COG1196 612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 966946461 884 TKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAE 926
Cdd:COG1196 692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
50-174 |
8.08e-13 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 72.59 E-value: 8.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 50 HLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQskCPAESVDSSGKTALHYAAAQGCLQAVQI 129
Cdd:PLN03192 563 HIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRILYH--FASISDPHAAGDLLCTAAKRNDLTAMKE 640
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 966946461 130 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRN 174
Cdd:PLN03192 641 LLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDKAN 685
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
52-203 |
9.42e-13 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 72.59 E-value: 9.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 52 AAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILc 131
Cdd:PLN03192 532 VASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRIL- 610
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966946461 132 EHKSPINLKDLDGNIpLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADL 203
Cdd:PLN03192 611 YHFASISDPHAAGDL-LCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADV 681
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
52-242 |
1.00e-12 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 71.53 E-value: 1.00e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 52 AAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHH-----------------------ECIRKLLQSKCPAESVD 108
Cdd:PHA02874 42 AIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHdiikllidngvdtsilpipciekDMIKTILDCGIDVNIKD 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 109 SSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIG 188
Cdd:PHA02874 122 AELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYG 201
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 966946461 189 SSNVVEALIKKGADLNLVDSLGHNALHYSKLSENAGIQsLLLSKIS---QDADLKTP 242
Cdd:PHA02874 202 DYACIKLLIDHGNHIMNKCKNGFTPLHNAIIHNRSAIE-LLINNASindQDIDGSTP 257
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
585-890 |
1.04e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.28 E-value: 1.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 585 EKAflfEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKE-AQAELEDYRKRKSLEDI 663
Cdd:COG1196 210 EKA---ERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAElEELRLELEELELELEEA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 664 TA-EYIHKAEHEKLmqltnvsrAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEnsvsitEHLQVITTLRTAAKEMEEK 742
Cdd:COG1196 287 QAeEYELLAELARL--------EQDIARLEERRRELEERLEELEEELAELEEELE------ELEEELEELEEELEEAEEE 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 743 ISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQ 822
Cdd:COG1196 353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966946461 823 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEAL 890
Cdd:COG1196 433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
59-208 |
1.53e-12 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 71.06 E-value: 1.53e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 59 ECLRVMVTHGVDVTAQDT-TGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPI 137
Cdd:PHA02878 148 EITKLLLSYGADINMKDRhKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGAST 227
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966946461 138 NLKDLDGNIPLLLAVQNGHS-EICHFLLDHGADVNSRNK-SGRTALMLAceIGSSNVVEALIKKGADLNLVDS 208
Cdd:PHA02878 228 DARDKCGNTPLHISVGYCKDyDILKLLLEHGVDVNAKSYiLGLTALHSS--IKSERKLKLLLEYGADINSLNS 298
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
47-222 |
1.57e-12 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 70.82 E-value: 1.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 47 HCFHLAAAKghVECLRVMVTHGVDVTAQDTTGHSALH--LAAKNSHHECIRKLLQSKCPAESVDSSGKTALH-YAAAQGC 123
Cdd:PHA03095 88 HLYLYNATT--LDVIKLLIKAGADVNAKDKVGRTPLHvyLSGFNINPKVIRLLLRKGADVNALDLYGMTPLAvLLKSRNA 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 124 -LQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHS--EICHFLLDHGADVNSRNKSGRTALMLACEIGSSN--VVEALIK 198
Cdd:PHA03095 166 nVELLRLLIDAGADVYAVDDRFRSLLHHHLQSFKPraRIVRELIRAGCDPAATDMLGNTPLHSMATGSSCKrsLVLPLLI 245
|
170 180
....*....|....*....|....
gi 966946461 199 KGADLNLVDSLGHNALHYSKLSEN 222
Cdd:PHA03095 246 AGISINARNRYGQTPLHYAAVFNN 269
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
335-891 |
4.73e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 4.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 335 ADQQDLLALLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDS-------YHSTQTDLGPSLGKPGETSPPDSKSSPPV 407
Cdd:TIGR02168 354 ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASlnneierLEARLERLEDRRERLQQEIEELLKKLEEA 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 408 LIHALGKSTTDSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNN-----TEISENSSDLSQKLK---- 478
Cdd:TIGR02168 434 ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQArldslERLQENLEGFSEGVKallk 513
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 479 ----------------ETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHLHE---LRVTEEEINVLK-QDLQNALEES 538
Cdd:TIGR02168 514 nqsglsgilgvlseliSVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQnelGRVTFLPLDSIKgTEIQGNDREI 593
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 539 ERNKEKVRELEEKLVEREK-----------GTVIKPPVEEYEEMKSSY---------------------------CSVIE 580
Cdd:TIGR02168 594 LKNIEGFLGVAKDLVKFDPklrkalsyllgGVLVVDDLDNALELAKKLrpgyrivtldgdlvrpggvitggsaktNSSIL 673
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 581 NMNKEKAFLFEKYQEAQEEIMKLKDTLksQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSL 660
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIAELEKAL--AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 661 EDITAEyihkaEHEKLMQLTNVSRAKAEDALSEMKSqyskvlnELTQLKQLVDAQKENSVSITEHLQ----VITTLRTAA 736
Cdd:TIGR02168 752 LSKELT-----ELEAEIEELEERLEEAEEELAEAEA-------EIEELEAQIEQLKEELKALREALDelraELTLLNEEA 819
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 737 KEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMtdamvprSSYEKLQSSLESEVSVLASKLKESVKEK---------- 806
Cdd:TIGR02168 820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDI-------ESLAAEIEELEELIEELESELEALLNERasleealall 892
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 807 ----EKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEmkRYS---ESSSKLEEDKDKKINEM 879
Cdd:TIGR02168 893 rselEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE--EYSltlEEAEALENKIEDDEEEA 970
|
650
....*....|..
gi 966946461 880 SKEVTKLKEALN 891
Cdd:TIGR02168 971 RRRLKRLENKIK 982
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
420-891 |
1.24e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 68.51 E-value: 1.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 420 DVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNT--EISENSSDLSQKLKETQSKYEEAMKEVLSVQKQ 497
Cdd:TIGR04523 32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKikILEQQIKDLNDKLKKNKDKINKLNSDLSKINSE 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 498 MK--------------------------LGLVSPESMDNYSHLHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEK 551
Cdd:TIGR04523 112 IKndkeqknklevelnklekqkkenkknIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDK 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 552 L-VEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQ--EASDEAEDMKEAMNR 628
Cdd:TIGR04523 192 IkNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQlnQLKDEQNKIKKQLSE 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 629 MIDEL---NKQVSELSQLYKEAQAELEDYRKRKSLEDITAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNEL 705
Cdd:TIGR04523 272 KQKELeqnNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKEL 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 706 TQL---------------KQLVDAQKENSvsitEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA 770
Cdd:TIGR04523 352 TNSesensekqreleekqNEIEKLKKENQ----SYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 771 MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQ 850
Cdd:TIGR04523 428 IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKE 507
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 966946461 851 AQEELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEALN 891
Cdd:TIGR04523 508 LEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELN 548
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
620-856 |
1.45e-11 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 68.50 E-value: 1.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 620 EDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDITAEyihkaeheklMQLTNVSRAKAEDALSEMKSQYS 699
Cdd:COG3206 167 ELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEE----------AKLLLQQLSELESQLAEARAELA 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 700 KVLNELTQLKQLVDAQKENSVSITEHlQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMtdamvpRS 779
Cdd:COG3206 237 EAEARLAALRAQLGSGPDALPELLQS-PVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQL------QQ 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 780 SYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQI---RSEVSQVKREKENIQTLLkskeqevNELLQKFQQAQEELA 856
Cdd:COG3206 310 EAQRILASLEAELEALQAREASLQAQLAQLEARLAELpelEAELRRLEREVEVARELY-------ESLLQRLEEARLAEA 382
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
308-891 |
1.49e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.54 E-value: 1.49e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 308 ISSIRENKDRLSDsttgadslldISSEADQQdlLALLQAKvASLTLHNKELQDKLqakspKEAEADLSFDSYHSTQTDLG 387
Cdd:TIGR02168 181 LERTRENLDRLED----------ILNELERQ--LKSLERQ-AEKAERYKELKAEL-----RELELALLVLRLEELREELE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 388 PSLGKpgETSPPDSKSSPPVLIHALGKSTTDSDVRIQQLQEILQDLQKRLES--SEAERKQLQVELQSRRAELVCLNNTE 465
Cdd:TIGR02168 243 ELQEE--LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAlaNEISRLEQQKQILRERLANLERQLEE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 466 ISENSSDLSQKLKETQ-------SKYEEAMKEVLSVQKQ----------MKLGLVSPES-MDNYS-----HLHELRVTEE 522
Cdd:TIGR02168 321 LEAQLEELESKLDELAeelaeleEKLEELKEELESLEAEleeleaeleeLESRLEELEEqLETLRskvaqLELQIASLNN 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 523 EINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTViKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMK 602
Cdd:TIGR02168 401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL-QAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 603 LKDTLKS---------QMTQEASDEAEDMKEAMNRMID----------------------------ELNKQVSELSQLYK 645
Cdd:TIGR02168 480 AERELAQlqarldsleRLQENLEGFSEGVKALLKNQSGlsgilgvlselisvdegyeaaieaalggRLQAVVVENLNAAK 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 646 EAQAELEDYRKRKS----LEDITAEYIHKAEHEKLMQLTNVSRAKAEdaLSEMKSQYSKVLN------------------ 703
Cdd:TIGR02168 560 KAIAFLKQNELGRVtflpLDSIKGTEIQGNDREILKNIEGFLGVAKD--LVKFDPKLRKALSyllggvlvvddldnalel 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 704 ----------------------------------------ELTQLKQLVDAQKEnsvSITEHLQVITTLRTAAKEMEEKI 743
Cdd:TIGR02168 638 akklrpgyrivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEE---KIAELEKALAELRKELEELEEEL 714
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 744 SNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQV 823
Cdd:TIGR02168 715 EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL 794
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966946461 824 KREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEALN 891
Cdd:TIGR02168 795 KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
422-809 |
2.48e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.04 E-value: 2.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQ------LQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKevlsvq 495
Cdd:COG1196 187 NLERLEDILGELERQLEPLERQAEKaeryreLKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEA------ 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 496 kqmklglvspesmdnyshlhELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKlverekgtvikppveeyeemkssy 575
Cdd:COG1196 261 --------------------ELAELEAELEELRLELEELELELEEAQAEEYELLAE------------------------ 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 576 csvIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEdmkeamnrmIDELNKQVSELSQLYKEAQAELEDYR 655
Cdd:COG1196 297 ---LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE---------LEELEEELEEAEEELEEAEAELAEAE 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 656 KRKSLEDITAEYIHKAEHEKLMQLTNVSRAKAEdALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTA 735
Cdd:COG1196 365 EALLEAEAELAEAEEELEELAEELLEALRAAAE-LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966946461 736 AKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSyEKLQSSLESEVSVLASKLKESVKEKEKV 809
Cdd:COG1196 444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE-AAARLLLLLEAEADYEGFLEGVKAALLL 516
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
80-215 |
4.27e-11 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 66.57 E-value: 4.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 80 SALHLAAKNSHHECIRKLLqsKCPaeSVD-----SSGKTALHYAAAQGCLQAVQILCEH-----KSPINLKDLDGNIPLL 149
Cdd:cd22192 19 SPLLLAAKENDVQAIKKLL--KCP--SCDlfqrgALGETALHVAALYDNLEAAVVLMEAapelvNEPMTSDLYQGETALH 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 150 LAVQNGHSEICHFLLDHGADVNS---------RNKS-----GRTALMLACEIGSSNVVEALIKKGADLNLVDSLGHNALH 215
Cdd:cd22192 95 IAVVNQNLNLVRELIARGADVVSpratgtffrPGPKnliyyGEHPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVLH 174
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
113-164 |
7.97e-11 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 58.05 E-value: 7.97e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 966946461 113 TALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLL 164
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
431-890 |
1.09e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 65.93 E-value: 1.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 431 QDLQKRLESSEAERKQLQVElQSRRAElvclnntEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDN 510
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAE-EAKKAD-------EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 511 YSHLHELRVTEEEINV--------LKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENM 582
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKAdaakkkaeEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAK 1444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 583 N----KEKAFLFEKYQEAQ---EEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAE----- 650
Cdd:PTZ00121 1445 KadeaKKKAEEAKKAEEAKkkaEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEeakka 1524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 651 -----LEDYRK----RKSLEDITAEYIHKAEH-EKLMQLTNVSRAKAEDALSEMKSQYSKVLN--ELTQLKQLVDAQKEN 718
Cdd:PTZ00121 1525 deakkAEEAKKadeaKKAEEKKKADELKKAEElKKAEEKKKAEEAKKAEEDKNMALRKAEEAKkaEEARIEEVMKLYEEE 1604
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 719 SVSITEHLQVITTLRTAAKEM--EEKISNLKEHLASKEVEVAKLEKQL--LEEKAAMTDAMVPRSSYEKLQSSLESEVSV 794
Cdd:PTZ00121 1605 KKMKAEEAKKAEEAKIKAEELkkAEEEKKKVEQLKKKEAEEKKKAEELkkAEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 795 LASKLK-ESVKEKEKVHSEVAQIRSEVSQVKREKENIQtllksKEQEVNELlqKFQQAQEELAEMKRYSESSSKLEEDKd 873
Cdd:PTZ00121 1685 EDEKKAaEALKKEAEEAKKAEELKKKEAEEKKKAEELK-----KAEEENKI--KAEEAKKEAEEDKKKAEEAKKDEEEK- 1756
|
490
....*....|....*..
gi 966946461 874 KKINEMSKEVTKLKEAL 890
Cdd:PTZ00121 1757 KKIAHLKKEEEKKAEEI 1773
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
58-231 |
3.65e-10 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 63.51 E-value: 3.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 58 VECLRVMVTHGVDVTAQDTTGHSALHLaaknshhecirkLLQSKCPAESVDssgktalhyaaaqgclqavqILCEHKSPI 137
Cdd:PHA03095 63 KDIVRLLLEAGADVNAPERCGFTPLHL------------YLYNATTLDVIK--------------------LLIKAGADV 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 138 NLKDLDGNIPL--LLAVQNGHSEICHFLLDHGADVNSRNKSGRTAlmLACEIGSSNV----VEALIKKGADLNLVDSLGH 211
Cdd:PHA03095 111 NAKDKVGRTPLhvYLSGFNINPKVIRLLLRKGADVNALDLYGMTP--LAVLLKSRNAnvelLRLLIDAGADVYAVDDRFR 188
|
170 180
....*....|....*....|..
gi 966946461 212 NALHYSKLS--ENAGIQSLLLS 231
Cdd:PHA03095 189 SLLHHHLQSfkPRARIVRELIR 210
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
517-891 |
4.77e-10 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 63.33 E-value: 4.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 517 LRVTEEEINVLKQDLQNALEESERNKEKVRELEEKlverekgtvikppveeYEEMKSSYcsvienmnKEKAFLFEKYQEA 596
Cdd:pfam06160 95 LDDIEEDIKQILEELDELLESEEKNREEVEELKDK----------------YRELRKTL--------LANRFSYGPAIDE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 597 QEEIMKLKDTLKSQMTQEASD----EAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDyrkrkSLEDItaeyihKAE 672
Cdd:pfam06160 151 LEKQLAEIEEEFSQFEELTESgdylEAREVLEKLEEETDALEELMEDIPPLYEELKTELPD-----QLEEL------KEG 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 673 HEKLM-QLTNVSRAKAEDALSEMKSQYSKVLNELTQLKqlVDAQKENSVSITEHLQ----VITTLRTAAKEMEEKISNLK 747
Cdd:pfam06160 220 YREMEeEGYALEHLNVDKEIQQLEEQLEENLALLENLE--LDEAEEALEEIEERIDqlydLLEKEVDAKKYVEKNLPEIE 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 748 EHLAskevEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVK---EKEKVHSEV----AQIRSEV 820
Cdd:pfam06160 298 DYLE----HAEEQNKELKEELERVQQSYTLNENELERVRGLEKQLEELEKRYDEIVErleEKEVAYSELqeelEEILEQL 373
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966946461 821 SQVKREKENIQTLLKS---KEQEVNELLQKFQQaqeELAEMKRYSESS--SKLEEDKDKKINEMSKEVTKLKEALN 891
Cdd:pfam06160 374 EEIEEEQEEFKESLQSlrkDELEAREKLDEFKL---ELREIKRLVEKSnlPGLPESYLDYFFDVSDEIEDLADELN 446
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
430-891 |
1.29e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 62.35 E-value: 1.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 430 LQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQK----------QMK 499
Cdd:TIGR04523 269 LSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKiisqlneqisQLK 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 500 LGLVSPESmDNYSHLHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLverekgtvikppvEEYEEMKSSYCSVI 579
Cdd:TIGR04523 349 KELTNSES-ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKI-------------QNQEKLNQQKDEQI 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 580 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEdmKEAMNRMIDELNKQVSELSQLYKEAQAELEDyrKRKS 659
Cdd:TIGR04523 415 KKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELI--IKNLDNTRESLETQLKVLSRSINKIKQNLEQ--KQKE 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 660 LEDITAEYIHKAEHEKLMQLTNvsrAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQViTTLRTAAKEM 739
Cdd:TIGR04523 491 LKSKEKELKKLNEEKKELEEKV---KDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKK-ENLEKEIDEK 566
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 740 EEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSV-------LASKLKESVKEKEKVHSE 812
Cdd:TIGR04523 567 NKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKakkenekLSSIIKNIKSKKNKLKQE 646
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 813 VAQIRSEVSQVKREKENIQT---LLKSKEQEVNELLQKFQQA-----QEELAEMKRYSESSskLEEDKDKKINEMSKEVT 884
Cdd:TIGR04523 647 VKQIKETIKEIRNKWPEIIKkikESKTKIDDIIELMKDWLKElslhyKKYITRMIRIKDLP--KLEEKYKEIEKELKKLD 724
|
....*..
gi 966946461 885 KLKEALN 891
Cdd:TIGR04523 725 EFSKELE 731
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
163-216 |
1.74e-09 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 54.27 E-value: 1.74e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 966946461 163 LLDHG-ADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDSLGHNALHY 216
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDL 55
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
147-197 |
1.93e-09 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 54.20 E-value: 1.93e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 966946461 147 PLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALI 197
Cdd:pfam13637 4 ALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
47-98 |
3.51e-09 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 53.43 E-value: 3.51e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 966946461 47 HCFHLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLL 98
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
517-891 |
3.58e-09 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 60.62 E-value: 3.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 517 LRVTEEEINVLKQDLQNALEESERNKEKVRELEEKlverekgtvikppveeYEEMKSSYcsvienmnKEKAFLF-EKYQE 595
Cdd:PRK04778 114 LDLIEEDIEQILEELQELLESEEKNREEVEQLKDL----------------YRELRKSL--------LANRFSFgPALDE 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 596 AQEEIMKLKDTLkSQMTQEASD----EAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDyrkrkSLEDItaeyihKA 671
Cdd:PRK04778 170 LEKQLENLEEEF-SQFVELTESgdyvEAREILDQLEEELAALEQIMEEIPELLKELQTELPD-----QLQEL------KA 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 672 EHEKLMQ----LTNVsraKAEDALSEMKSQYSKVLNELTQLKqlVDAQKENSVSITEHLQ----VITTLRTAAKEMEEKI 743
Cdd:PRK04778 238 GYRELVEegyhLDHL---DIEKEIQDLKEQIDENLALLEELD--LDEAEEKNEEIQERIDqlydILEREVKARKYVEKNS 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 744 SNLKEHL--ASKEVEVAKLEKQLLEEKAAMTDAMVprSSYEKLQSSLESEVSVLaSKLKESVKEKEKVHSEV----AQIR 817
Cdd:PRK04778 313 DTLPDFLehAKEQNKELKEEIDRVKQSYTLNESEL--ESVRQLEKQLESLEKQY-DEITERIAEQEIAYSELqeelEEIL 389
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966946461 818 SEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSS--KLEEDKDKKINEMSKEVTKLKEALN 891
Cdd:PRK04778 390 KQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNKLHEIKRYLEKSNlpGLPEDYLEMFFEVSDEIEALAEELE 465
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
56-230 |
6.25e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 59.23 E-value: 6.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 56 GHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIrKLLQSKCPAESVDSSG-KTALHYAAAQGCLQAVQILCEHK 134
Cdd:PHA02875 13 GELDIARRLLDIGINPNFEIYDGISPIKLAMKFRDSEAI-KLLMKHGAIPDVKYPDiESELHDAVEEGDVKAVEELLDLG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 135 SPINlkDL---DGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDSLGH 211
Cdd:PHA02875 92 KFAD--DVfykDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGC 169
|
170
....*....|....*....
gi 966946461 212 NALHYSKLSENAGIQSLLL 230
Cdd:PHA02875 170 TPLIIAMAKGDIAICKMLL 188
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
422-801 |
8.02e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.40 E-value: 8.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAElvcLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQ------ 495
Cdd:COG4717 89 EYAELQEELEELEEELEELEAELEELREELEKLEKL---LQLLPLYQELEALEAELAELPERLEELEERLEELReleeel 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 496 -------KQMKLGLVSPESMDNYSHLHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEY 568
Cdd:COG4717 166 eeleaelAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERL 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 569 EEMKSSYCS-----VIENMNKEKAFLFEKYQEAQ---------EEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDEL- 633
Cdd:COG4717 246 KEARLLLLIaaallALLGLGGSLLSLILTIAGVLflvlgllalLFLLLAREKASLGKEAEELQALPALEELEEEELEELl 325
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 634 -------NKQVSELSQLY------KEAQAELEDYRKRKSLEDitaeyiHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSK 700
Cdd:COG4717 326 aalglppDLSPEELLELLdrieelQELLREAEELEEELQLEE------LEQEIAALLAEAGVEDEEELRAALEQAEEYQE 399
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 701 VLNELTQLKQLVDAQKENSVSITEHLQvittlrtaAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMtDAMVPRSS 780
Cdd:COG4717 400 LKEELEELEEQLEELLGELEELLEALD--------EEELEEELEELEEELEELEEELEELREELAELEAEL-EQLEEDGE 470
|
410 420
....*....|....*....|.
gi 966946461 781 YEKLQSSLESEVSVLASKLKE 801
Cdd:COG4717 471 LAELLQELEELKAELRELAEE 491
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
50-230 |
9.13e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 59.31 E-value: 9.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 50 HLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSgktaLHYAAAQGCLQAVQI 129
Cdd:PHA02876 183 HYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNINKNDLS----LLKAIRNEDLETSLL 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 130 LCEHKSPINLKDLDGNIPLLLAVQNGH-SEICHFLLDHGADVNSRNKSGRTALMLACEIG-SSNVVEALIKKGADLNLVD 207
Cdd:PHA02876 259 LYDAGFSVNSIDDCKNTPLHHASQAPSlSRLVPKLLERGADVNAKNIKGETPLYLMAKNGyDTENIRTLIMLGADVNAAD 338
|
170 180
....*....|....*....|....
gi 966946461 208 SLGHNALHY-SKLSENAGIQSLLL 230
Cdd:PHA02876 339 RLYITPLHQaSTLDRNKDIVITLL 362
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
49-207 |
9.69e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 59.31 E-value: 9.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 49 FHLAAAKGH-VECLRVMVTHGVDVTAQDTTGHSALHLAAK-NSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQA 126
Cdd:PHA02876 311 LYLMAKNGYdTENIRTLIMLGADVNAADRLYITPLHQASTlDRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVI 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 127 VQILCEHKSPINL--KDLDGNIPLLLAVQNGHSEIcHFLLDHGADVNSRNKSGRTALMLACEIGSS-NVVEALIKKGADL 203
Cdd:PHA02876 391 INTLLDYGADIEAlsQKIGTALHFALCGTNPYMSV-KTLIDRGANVNSKNKDLSTPLHYACKKNCKlDVIEMLLDNGADV 469
|
....
gi 966946461 204 NLVD 207
Cdd:PHA02876 470 NAIN 473
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
78-130 |
1.14e-08 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 51.89 E-value: 1.14e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 966946461 78 GHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQIL 130
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
82-232 |
1.46e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 58.14 E-value: 1.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 82 LHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGC-----LQAVQILCEHKSPINLKDLDGNIPLLLAVQN-- 154
Cdd:PHA03100 39 LYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHYLSNIKYnltdvKEIVKLLLEYGANVNAPDNNGITPLLYAISKks 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 155 GHSEICHFLLDHGADVNSRNKSGRTALMLACE------------------IGSSNVVEALIKKGADLNLVDSLGHNALHY 216
Cdd:PHA03100 119 NSYSIVEYLLDNGANVNIKNSDGENLLHLYLEsnkidlkilkllidkgvdINAKNRVNYLLSYGVPINIKDVYGFTPLHY 198
|
170
....*....|....*.
gi 966946461 217 SKLSENAGIQSLLLSK 232
Cdd:PHA03100 199 AVYNNNPEFVKYLLDL 214
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
64-217 |
1.65e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 58.54 E-value: 1.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 64 MVTHGVDVTAQDTTGHSALHLAAKNSHH-ECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQI-LCEHKSPINLKD 141
Cdd:PHA02876 293 LLERGADVNAKNIKGETPLYLMAKNGYDtENIRTLIMLGADVNAADRLYITPLHQASTLDRNKDIVItLLELGANVNARD 372
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966946461 142 LDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLA-CEIGSSNVVEALIKKGADLNLVDSLGHNALHYS 217
Cdd:PHA02876 373 YCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFAlCGTNPYMSVKTLIDRGANVNSKNKDLSTPLHYA 449
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
422-911 |
1.80e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.00 E-value: 1.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLG 501
Cdd:PTZ00121 1225 KAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA 1304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 502 LVSPESMDNYSHLHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKppvEEYEEMKSSYCSVIEN 581
Cdd:PTZ00121 1305 DEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK---AEAAEKKKEEAKKKAD 1381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 582 MNKEKAFLFEKYQEAQ---EEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSElSQLYKEAQAELEDYRKRK 658
Cdd:PTZ00121 1382 AAKKKAEEKKKADEAKkkaEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE-AKKADEAKKKAEEAKKAE 1460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 659 SLEDiTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTA--A 736
Cdd:PTZ00121 1461 EAKK-KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAdeA 1539
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 737 KEMEEKiSNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQI 816
Cdd:PTZ00121 1540 KKAEEK-KKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 817 RSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKkinemSKEVTKLKEALNSLSQL 896
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK-----AEEAKKAEEDEKKAAEA 1693
|
490
....*....|....*
gi 966946461 897 SYSTSSSKRQSQQLE 911
Cdd:PTZ00121 1694 LKKEAEEAKKAEELK 1708
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
417-884 |
1.91e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 58.59 E-value: 1.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 417 TDSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVClNNTEISENSSDLSQKLKETQSKYEEAMKEVlsvQK 496
Cdd:pfam15921 274 SEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMR-QLSDLESTVSQLRSELREAKRMYEDKIEEL---EK 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 497 QMKLGlvspesmdnYSHLHELRVTEEEINVLKQDLQNALEE-----SERNKEKVRELEE--KLVEREKGTVIkppveeye 569
Cdd:pfam15921 350 QLVLA---------NSELTEARTERDQFSQESGNLDDQLQKlladlHKREKELSLEKEQnkRLWDRDTGNSI-------- 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 570 emkssycsVIENMNKEkaflfekYQEAQEEIMKLKDTLKSqMTQEASDEAEDMKEAMNRMIDELNKqVSELSqlykeAQA 649
Cdd:pfam15921 413 --------TIDHLRRE-------LDDRNMEVQRLEALLKA-MKSECQGQMERQMAAIQGKNESLEK-VSSLT-----AQL 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 650 ELEDYRKRKSLEDITAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKV-------LNELTQLK----QLVDAQKEN 718
Cdd:pfam15921 471 ESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLrsrvdlkLQELQHLKnegdHLRNVQTEC 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 719 S---VSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVL 795
Cdd:pfam15921 551 EalkLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDL 630
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 796 A--------------SKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEV----NELLQKFQQAQEELAE 857
Cdd:pfam15921 631 ElekvklvnagserlRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMetttNKLKMQLKSAQSELEQ 710
|
490 500
....*....|....*....|....*..
gi 966946461 858 MKRYSESSSKLEEDKDKKINEMSKEVT 884
Cdd:pfam15921 711 TRNTLKSMEGSDGHAMKVAMGMQKQIT 737
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
414-713 |
2.42e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.16 E-value: 2.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 414 KSTTDSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELvclnnteiSENSSDLSQKlKETQSKYEEAMKEVls 493
Cdd:TIGR02169 716 RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSEL--------KELEARIEEL-EEDLHKLEEALNDL-- 784
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 494 vqKQMKLGLVSPESMDNYSHLHE--------LRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKgtvikpPV 565
Cdd:TIGR02169 785 --EARLSHSRIPEIQAELSKLEEevsriearLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK------EI 856
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 566 EEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMT--QEASDEAEDMKEAMNRMIDELNKQVSELSQL 643
Cdd:TIGR02169 857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERkiEELEAQIEKKRKRLSELKAKLEALEEELSEI 936
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966946461 644 YKEAQAELEDYRKRKSLEDITAEYihKAEHEKLMQLTNVSR------AKAEDALSEMKSQYSKVLNELTQLKQLVD 713
Cdd:TIGR02169 937 EDPKGEDEEIPEEELSLEDVQAEL--QRVEEEIRALEPVNMlaiqeyEEVLKRLDELKEKRAKLEEERKAILERIE 1010
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
423-888 |
2.58e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 58.13 E-value: 2.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 423 IQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS-DLSQKLKETQSKYEEAMKE--VLSVQKQMK 499
Cdd:TIGR00606 586 INQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSqDEESDLERLKEEIEKSSKQraMLAGATAVY 665
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 500 LGLVSPESMDNYSHL---HELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEyeemkssyc 576
Cdd:TIGR00606 666 SQFITQLTDENQSCCpvcQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQ--------- 736
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 577 SVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQ----EASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELE 652
Cdd:TIGR00606 737 SIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLlgtiMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQ 816
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 653 DYRKRKSLEDITAEYIHKAEH-----------EKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVS 721
Cdd:TIGR00606 817 GSDLDRTVQQVNQEKQEKQHEldtvvskielnRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTE 896
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 722 ITEHLQVI-----------TTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAM-VPRSSYEKLQSSLE 789
Cdd:TIGR00606 897 VQSLIREIkdakeqdspleTFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIEnKIQDGKDDYLKQKE 976
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 790 SEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQT--LLKSKEQEVNELLQKFQQAQEELAEMK--RYSESS 865
Cdd:TIGR00606 977 TELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDnlTLRKRENELKEVEEELKQHLKEMGQMQvlQMKQEH 1056
|
490 500
....*....|....*....|...
gi 966946461 866 SKLEEDKDKKINEMSKEVTKLKE 888
Cdd:TIGR00606 1057 QKLEENIDLIKRNHVLALGRQKG 1079
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
181-243 |
3.50e-08 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 51.66 E-value: 3.50e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966946461 181 LMLACEIGSSNVVEALIKKGADLNLVDSLGHNALHYSKLSENAGIQSLLLSKISQDADLKTPT 243
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNLKDNGRT 63
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
518-888 |
3.77e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 57.36 E-value: 3.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 518 RVTEEEINVLKQ-DLQNALEESERNKEKVRELEEKLVErekgtvIKPPVEEYEEMKSSYCSVIENMNKekafLFEKYQEA 596
Cdd:PRK02224 180 RVLSDQRGSLDQlKAQIEEKEEKDLHERLNGLESELAE------LDEEIERYEEQREQARETRDEADE----VLEEHEER 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 597 QEEIMKLKDTLKSqmTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEdyrkrksLEDITAEYI--HKAEHE 674
Cdd:PRK02224 250 REELETLEAEIED--LRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAG-------LDDADAEAVeaRREELE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 675 KlmqltnvSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSvsitehlqviTTLRTAAKEMEEKISNLKEHLASKE 754
Cdd:PRK02224 321 D-------RDEELRDRLEECRVAAQAHNEEAESLREDADDLEERA----------EELREEAAELESELEEAREAVEDRR 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 755 VEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKE---SVKEKEKVHSEVAQIRSE------------ 819
Cdd:PRK02224 384 EEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAEleaTLRTARERVEEAEALLEAgkcpecgqpveg 463
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 820 ------VSQVKREKENIQTLLKSKEQEVNELLQKFQQAqEELAEMKRYSES-------SSKLEEDKDKKINEMSKEVTKL 886
Cdd:PRK02224 464 sphvetIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERleerredLEELIAERRETIEEKRERAEEL 542
|
..
gi 966946461 887 KE 888
Cdd:PRK02224 543 RE 544
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
523-890 |
3.77e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 57.38 E-value: 3.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 523 EINVLKQDLQNALEESERNKEKVRELEEKLVE-----REKGTVIKPPVEEYEEMKSSYcsvienmnKEKAFLFEKYQEAQ 597
Cdd:PRK03918 173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEvlreiNEISSELPELREELEKLEKEV--------KELEELKEEIEELE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 598 EEIMKLKDTLKSqmTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAqaelEDYRKRKSLEDITAEYIHKAEHE--K 675
Cdd:PRK03918 245 KELESLEGSKRK--LEEKIRELEERIEELKKEIEELEEKVKELKELKEKA----EEYIKLSEFYEEYLDELREIEKRlsR 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 676 LMQLTNVSRAKAEDA------LSEMKSQYSKVLNELTQLKQLVDA---------------QKENSVSITEHLQVITTLRT 734
Cdd:PRK03918 319 LEEEINGIEERIKELeekeerLEELKKKLKELEKRLEELEERHELyeeakakkeelerlkKRLTGLTPEKLEKELEELEK 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 735 AAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPR------------SSYEKLQSSLESEVSVLASKLKES 802
Cdd:PRK03918 399 AKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGrelteehrkellEEYTAELKRIEKELKEIEEKERKL 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 803 VKEKEKVHSEvaqiRSEVSQVKREKEnIQTLLKSKEQEVNEL-LQKFQQAQEELAEMKRYS---ESSSKLEEDKDKKINE 878
Cdd:PRK03918 479 RKELRELEKV----LKKESELIKLKE-LAEQLKELEEKLKKYnLEELEKKAEEYEKLKEKLiklKGEIKSLKKELEKLEE 553
|
410
....*....|..
gi 966946461 879 MSKEVTKLKEAL 890
Cdd:PRK03918 554 LKKKLAELEKKL 565
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
49-217 |
5.31e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 56.43 E-value: 5.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 49 FHLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQS--KCPAESVDSSGKTALHY--------- 117
Cdd:PHA02878 41 LHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHIICKEPNKLGMKEMIRSinKCSVFYTLVAIKDAFNNrnveifkii 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 118 ------------------AAAQGCLQA--VQILCEHKSPINLKDLD-GNIPLLLAVQNGHSEICHFLLDHGADVNSRNKS 176
Cdd:PHA02878 121 ltnrykniqtidlvyidkKSKDDIIEAeiTKLLLSYGADINMKDRHkGNTALHYATENKDQRLTELLLSYGANVNIPDKT 200
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 966946461 177 GRTALMLACEIGSSNVVEALIKKGADLNLVDSLGHNALHYS 217
Cdd:PHA02878 201 NNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHIS 241
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
613-859 |
5.32e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.00 E-value: 5.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 613 QEASDEAEDMKEAMNRMIDELNKQ---VSELSQLYKEAQAELEDYRKRksLEDITAEyiHKAEHEKLMQLTNVSRAKaED 689
Cdd:TIGR02169 677 QRLRERLEGLKRELSSLQSELRRIenrLDELSQELSDASRKIGEIEKE--IEQLEQE--EEKLKERLEELEEDLSSL-EQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 690 ALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHL--QVITTLRTAAKEMEEKISNLKEHLASKEVEVAK--LEKQLL 765
Cdd:TIGR02169 752 EIENVKSELKELEARIEELEEDLHKLEEALNDLEARLshSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRltLEKEYL 831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 766 EEKaaMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELL 845
Cdd:TIGR02169 832 EKE--IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE 909
|
250
....*....|....
gi 966946461 846 QKFQQAQEELAEMK 859
Cdd:TIGR02169 910 AQIEKKRKRLSELK 923
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
422-934 |
5.33e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.99 E-value: 5.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNnTEISEnssdLSQKLKETQSKYEEAMKEVLSVQKQMKLG 501
Cdd:TIGR02168 233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR-LEVSE----LEEEIEELQKELYALANEISRLEQQKQIL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 502 LVSPESMDNyshlhELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKgtVIKPPVEEYEEMKSSYCSVIEN 581
Cdd:TIGR02168 308 RERLANLER-----QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA--ELEELEAELEELESRLEELEEQ 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 582 MNKEKAFLFEKYQE---AQEEIMKLKDTLKS------QMTQEASDEAEDMKEAMnrmIDELNKQVSELSQLYKEAQAELE 652
Cdd:TIGR02168 381 LETLRSKVAQLELQiasLNNEIERLEARLERledrreRLQQEIEELLKKLEEAE---LKELQAELEELEEELEELQEELE 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 653 DYRKRKSLEDITAEYIHKAEHEKLMQLTNV-SRAKAEDALSEMKSQYSKVLNELTQ-----------LKQL--VDAQKEN 718
Cdd:TIGR02168 458 RLEEALEELREELEEAEQALDAAERELAQLqARLDSLERLQENLEGFSEGVKALLKnqsglsgilgvLSELisVDEGYEA 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 719 SVSIT--EHLQ--VITTLRTAAKEmeekISNLKEHLASK-------EVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSS 787
Cdd:TIGR02168 538 AIEAAlgGRLQavVVENLNAAKKA----IAFLKQNELGRvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 788 LESEVSVL----------------ASKLKE-----------------SVKEKEKVHSEVAQIRSEVSQVKREKENIQTLL 834
Cdd:TIGR02168 614 LRKALSYLlggvlvvddldnalelAKKLRPgyrivtldgdlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKI 693
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 835 KSKEQEVNELLQKFQQAQEELAEMKrysesssKLEEDKDKKINEMSKEVTKL-KEALNSLSQLSYSTSSSKRQSQQLEAL 913
Cdd:TIGR02168 694 AELEKALAELRKELEELEEELEQLR-------KELEELSRQISALRKDLARLeAEVEQLEERIAQLSKELTELEAEIEEL 766
|
570 580
....*....|....*....|.
gi 966946461 914 QQQVKQLQNQLAECKKHHQEV 934
Cdd:TIGR02168 767 EERLEEAEEELAEAEAEIEEL 787
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
514-887 |
5.95e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 56.70 E-value: 5.95e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 514 LHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKA------ 587
Cdd:COG4717 80 LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEErleelr 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 588 FLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRmIDELNKQVSELSQLYKEAQAELEDYRKRksLEDITAEY 667
Cdd:COG4717 160 ELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE-LEELQQRLAELEEELEEAQEELEELEEE--LEQLENEL 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 668 IHKAEHEKLMQLTNVSRAKAE------------------------------DALSEMKSQYSKVLNELTQLKQLVDAQKE 717
Cdd:COG4717 237 EAAALEERLKEARLLLLIAAAllallglggsllsliltiagvlflvlgllaLLFLLLAREKASLGKEAEELQALPALEEL 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 718 NSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAmvprSSYEKLQSSLESEVSVLAS 797
Cdd:COG4717 317 EEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA----ALLAEAGVEDEEELRAALE 392
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 798 KLKESVKEKEKVHSEVAQIRSEVS------------QVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESS 865
Cdd:COG4717 393 QAEEYQELKEELEELEEQLEELLGeleellealdeeELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELA 472
|
410 420
....*....|....*....|....
gi 966946461 866 SKLE--EDKDKKINEMSKEVTKLK 887
Cdd:COG4717 473 ELLQelEELKAELRELAEEWAALK 496
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
426-885 |
7.32e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 56.57 E-value: 7.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 426 LQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS-----DLSQKLKETQSKYEEAMKEVLSVQKQMKL 500
Cdd:TIGR04523 157 LNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLlsnlkKKIQKNKSLESQISELKKQNNQLKDNIEK 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 501 GLVSPESMDNyshlhELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKgtvikppveEYEEMKSSycsvIE 580
Cdd:TIGR04523 237 KQQEINEKTT-----EISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEK---------QLNQLKSE----IS 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 581 NMNKEK-AFLFEKYQEAQEEIMKLKDTLKSQMTQ--EASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKR 657
Cdd:TIGR04523 299 DLNNQKeQDWNKELKSELKNQEKKLEEIQNQISQnnKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 658 KS--LEDITAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHlqvITTLRTA 735
Cdd:TIGR04523 379 NQsyKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQ---DSVKELI 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 736 AKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQ 815
Cdd:TIGR04523 456 IKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKE 535
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966946461 816 IRSEVSQVKREKENIQTLLKSK--EQEVNELLQKFQQAQEELAEMKRyseSSSKLEE---DKDKKINEMSKEVTK 885
Cdd:TIGR04523 536 KESKISDLEDELNKDDFELKKEnlEKEIDEKNKEIEELKQTQKSLKK---KQEEKQElidQKEKEKKDLIKEIEE 607
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
94-166 |
1.22e-07 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 55.67 E-value: 1.22e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966946461 94 IRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDH 166
Cdd:PTZ00322 98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRH 170
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
514-888 |
1.37e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 55.82 E-value: 1.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 514 LHELRVTEEEINVLKQ---DLQNALEESERNKE----KVRELEEKLVEREkgtvikppvEEYEEMKSSyCSV----IENM 582
Cdd:PRK02224 243 LEEHEERREELETLEAeieDLRETIAETEREREelaeEVRDLRERLEELE---------EERDDLLAE-AGLddadAEAV 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 583 NKEKAFLFEKYQEAQEEIMKlkdtlKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKS-LE 661
Cdd:PRK02224 313 EARREELEDRDEELRDRLEE-----CRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREeIE 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 662 DITAEYihkAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL--------------KQLVDAQK----ENSVSIT 723
Cdd:PRK02224 388 ELEEEI---EELRERFGDAPVDLGNAEDFLEELREERDELREREAELeatlrtarerveeaEALLEAGKcpecGQPVEGS 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 724 EHLQVITtlrtaakEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAmtdamvprssyeklqSSLESEVSVLASKLKESV 803
Cdd:PRK02224 465 PHVETIE-------EDRERVEELEAELEDLEEEVEEVEERLERAEDL---------------VEAEDRIERLEERREDLE 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 804 KEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEM-KRYSESSSKLE-----EDKDKKIN 877
Cdd:PRK02224 523 ELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELnSKLAELKERIEsleriRTLLAAIA 602
|
410
....*....|.
gi 966946461 878 EMSKEVTKLKE 888
Cdd:PRK02224 603 DAEDEIERLRE 613
|
|
| trp |
TIGR00870 |
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ... |
75-219 |
1.69e-07 |
|
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 55.47 E-value: 1.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 75 DTTGHSALHLAAKNSHHECIRKLLQSKCPAESVdssGKTALHyAAAQGCLQAVQILCEHKSPINLKDLD----------- 143
Cdd:TIGR00870 49 DRLGRSALFVAAIENENLELTELLLNLSCRGAV---GDTLLH-AISLEYVDAVEAILLHLLAAFRKSGPlelandqytse 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 144 ---GNIPLLLAVQNGHSEICHFLLDHGADVNSRNKS--------------GRTALMLACEIGSSNVVEALIKKGADLNLV 206
Cdd:TIGR00870 125 ftpGITALHLAAHRQNYEIVKLLLERGASVPARACGdffvksqgvdsfyhGESPLNAAACLGSPSIVALLSEDPADILTA 204
|
170
....*....|...
gi 966946461 207 DSLGHNALHYSKL 219
Cdd:TIGR00870 205 DSLGNTLLHLLVM 217
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
68-238 |
1.87e-07 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 55.07 E-value: 1.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 68 GVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYA-AAQGCLQAVQILCEHKSPINLKDLDGNI 146
Cdd:PHA02876 365 GANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFAlCGTNPYMSVKTLIDRGANVNSKNKDLST 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 147 PLLLAVQNG-HSEICHFLLDHGADVNSRNKSGRTALMLAceIGSSNVVEALIKKGADLN----LVDSLGHNALHYSKLSE 221
Cdd:PHA02876 445 PLHYACKKNcKLDVIEMLLDNGADVNAINIQNQYPLLIA--LEYHGIVNILLHYGAELRdsrvLHKSLNDNMFSFRYIIA 522
|
170
....*....|....*..
gi 966946461 222 NAGIQSLLLSKISQDAD 238
Cdd:PHA02876 523 HICIQDFIRHDIRNEVN 539
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
110-221 |
2.47e-07 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 54.50 E-value: 2.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 110 SGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLAC-EIG 188
Cdd:PHA02878 167 KGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVgYCK 246
|
90 100 110
....*....|....*....|....*....|....
gi 966946461 189 SSNVVEALIKKGADLNLVDS-LGHNALHYSKLSE 221
Cdd:PHA02878 247 DYDILKLLLEHGVDVNAKSYiLGLTALHSSIKSE 280
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
422-909 |
2.58e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 54.80 E-value: 2.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVElqsrraelvclnNTEISENSSDLSQKLKEtqskyEEAMKEVLSVQKqmklg 501
Cdd:pfam01576 69 RKQELEEILHELESRLEEEEERSQQLQNE------------KKKMQQHIQDLEEQLDE-----EEAARQKLQLEK----- 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 502 lVSPESmdnyshlhELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKgtvikpPVEEYEEMKSSYCSVIEN 581
Cdd:pfam01576 127 -VTTEA--------KIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEE------KAKSLSKLKNKHEAMISD 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 582 MN--------------KEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEdMKEAMNRMIDELNKQVSELSQLyKEA 647
Cdd:pfam01576 192 LEerlkkeekgrqeleKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEE-LQAALARLEEETAQKNNALKKI-REL 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 648 QAELEDYRkrkslEDITAEYIHKAEHEK----LMQLTNVSRAKAEDALSEMKSQY---SKVLNELTQLKQLVDAQKENsv 720
Cdd:pfam01576 270 EAQISELQ-----EDLESERAARNKAEKqrrdLGEELEALKTELEDTLDTTAAQQelrSKREQEVTELKKALEEETRS-- 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 721 siteHLQVITTLR----TAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLA 796
Cdd:pfam01576 343 ----HEAQLQEMRqkhtQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQ 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 797 SKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKR----YSESSSKLEEDK 872
Cdd:pfam01576 419 ARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRqklnLSTRLRQLEDER 498
|
490 500 510
....*....|....*....|....*....|....*..
gi 966946461 873 DKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQ 909
Cdd:pfam01576 499 NSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEE 535
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
420-600 |
3.32e-07 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 52.23 E-value: 3.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 420 DVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNnTEISENSSDLSQkLKETQSKYEEAMKEVLSvQKQMK 499
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLE-KEIKRLELEIEE-VEARIKKYEEQLGNVRN-NKEYE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 500 lglvspesmdnySHLHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREkgtvikppvEEYEEMKSSYCSVI 579
Cdd:COG1579 93 ------------ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELE---------AELEEKKAELDEEL 151
|
170 180
....*....|....*....|.
gi 966946461 580 ENMNKEKAFLFEKYQEAQEEI 600
Cdd:COG1579 152 AELEAELEELEAEREELAAKI 172
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
422-858 |
6.15e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 53.51 E-value: 6.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLN--NTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQM- 498
Cdd:PRK02224 315 RREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEerAEELREEAAELESELEEAREAVEDRREEIEELEEEIe 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 499 ---KLGLVSPESMDNYSHLHELRvtEEEINVLKQDLqNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEyeemkSSY 575
Cdd:PRK02224 395 elrERFGDAPVDLGNAEDFLEEL--REERDELRERE-AELEATLRTARERVEEAEALLEAGKCPECGQPVEG-----SPH 466
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 576 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLksqmtqeasDEAEDMKEAMNRmIDELNKQVSELSQLYKEAQAELEDyr 655
Cdd:PRK02224 467 VETIEEDRERVEELEAELEDLEEEVEEVEERL---------ERAEDLVEAEDR-IERLEERREDLEELIAERRETIEE-- 534
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 656 KRKSLEDITAEyihKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQ---KENSVSITEHLQVITTL 732
Cdd:PRK02224 535 KRERAEELRER---AAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLeriRTLLAAIADAEDEIERL 611
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 733 RTAAKEMEEKISNLKEHLASKEVEVAKLEKQLleEKAAMTDAmvpRSSYEKLQSSLESevsvLASKLKESVKEKEKVHSE 812
Cdd:PRK02224 612 REKREALAELNDERRERLAEKRERKRELEAEF--DEARIEEA---REDKERAEEYLEQ----VEEKLDELREERDDLQAE 682
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 966946461 813 VAQIRSEVSQVKREKENIQTLlkskeQEVNELLQKFQQAQEELAEM 858
Cdd:PRK02224 683 IGAVENELEELEELRERREAL-----ENRVEALEALYDEAEELESM 723
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
591-891 |
6.31e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.53 E-value: 6.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 591 EKYQEAQEEIMKLKDTLKSQMTQ-----EASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDITA 665
Cdd:PRK03918 158 DDYENAYKNLGEVIKEIKRRIERlekfiKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELK 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 666 EYIHKAEHEKLMQLTNVsrAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLqvitTLRTAAKEMEEKISN 745
Cdd:PRK03918 238 EEIEELEKELESLEGSK--RKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYI----KLSEFYEEYLDELRE 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 746 LKEHLASKEVEVAKLEKQLLEekaamtdamvprssyeklQSSLESEVSVLASKLKESVKEKEKVhSEVAQIRSEVSQVKR 825
Cdd:PRK03918 312 IEKRLSRLEEEINGIEERIKE------------------LEEKEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKE 372
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966946461 826 EKENIQTLLKSKE-QEVNELLQKFQQAQEELaemkrySESSSKLEEdkdkKINEMSKEVTKLKEALN 891
Cdd:PRK03918 373 ELERLKKRLTGLTpEKLEKELEELEKAKEEI------EEEISKITA----RIGELKKEIKELKKAIE 429
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
51-181 |
6.60e-07 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 53.09 E-value: 6.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 51 LAAAKGHVECL-RVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQS-----KCPAESVDSSGKTALHYAAAQGCL 124
Cdd:cd22192 23 LAAKENDVQAIkKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAapelvNEPMTSDLYQGETALHIAVVNQNL 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966946461 125 QAVQIL---------------CEHKSPINLKDLdGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTAL 181
Cdd:cd22192 103 NLVRELiargadvvspratgtFFRPGPKNLIYY-GEHPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVL 173
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
119-198 |
6.72e-07 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 53.36 E-value: 6.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 119 AAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIK 198
Cdd:PTZ00322 90 AASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSR 169
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
55-171 |
6.85e-07 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 52.75 E-value: 6.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 55 KGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHEC-IRKLLQSK-----------------CPAESVDSSGKTALH 116
Cdd:PHA03100 118 SNSYSIVEYLLDNGANVNIKNSDGENLLHLYLESNKIDLkILKLLIDKgvdinaknrvnyllsygVPINIKDVYGFTPLH 197
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 966946461 117 YAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVN 171
Cdd:PHA03100 198 YAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSIK 252
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
141-251 |
7.32e-07 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 52.98 E-value: 7.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 141 DLDGNIPLLLAVqnghsEICHF-----------LLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDSL 209
Cdd:PTZ00322 73 VIDPVVAHMLTV-----ELCQLaasgdavgariLLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKD 147
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 966946461 210 GHNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQV 251
Cdd:PTZ00322 148 GKTPLELAEENGFREVVQLLSRHSQCHFELGANAKPDSFTGK 189
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
44-184 |
7.35e-07 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 52.96 E-value: 7.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 44 KLKHCFHLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQgC 123
Cdd:PHA02878 167 KGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGY-C 245
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966946461 124 L--QAVQILCEHKSPINLKD-LDGNIPLLLAVqngHSE-ICHFLLDHGADVNSRNKSGRTALMLA 184
Cdd:PHA02878 246 KdyDILKLLLEHGVDVNAKSyILGLTALHSSI---KSErKLKLLLEYGADINSLNSYKLTPLSSA 307
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
434-885 |
8.06e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.22 E-value: 8.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 434 QKRLESSEAERKQLQVELQSRRAELVclNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLglvspESMDNYSH 513
Cdd:PTZ00121 1451 KKAEEAKKAEEAKKKAEEAKKADEAK--KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA-----KKAEEAKK 1523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 514 LHELRVTEEEINVlkQDLQNAleESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEmkssycsvieNMNKEKAFLFEKY 593
Cdd:PTZ00121 1524 ADEAKKAEEAKKA--DEAKKA--EEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK----------NMALRKAEEAKKA 1589
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 594 QEAQ-EEIMKLKDTLKSQMTQEASDEAEDMKEAMN-RMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDITAEYIHKA 671
Cdd:PTZ00121 1590 EEARiEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKK 1669
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 672 EHEKlmqltnvsRAKAEDALSEMKSQYSKvlneltqlkqlvdaqKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA 751
Cdd:PTZ00121 1670 AEED--------KKKAEEAKKAEEDEKKA---------------AEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEE 1726
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 752 SKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQ--SSLESEVSVLASKLKESVKE---KEKVHSEVAQIRSEVSQVKRE 826
Cdd:PTZ00121 1727 ENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAhlKKEEEKKAEEIRKEKEAVIEeelDEEDEKRRMEVDKKIKDIFDN 1806
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 827 KENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYS-ESSSKLEEDKDKKINEMSKEVTK 885
Cdd:PTZ00121 1807 FANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQlEEADAFEKHKFNKNNENGEDGNK 1866
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
546-766 |
9.36e-07 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 52.71 E-value: 9.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 546 RELEEKLVE----REKGTVIKPPVEE-YEEMKSsyCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAE 620
Cdd:PHA02562 153 RKLVEDLLDisvlSEMDKLNKDKIRElNQQIQT--LDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAK 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 621 DMKEAMNRMIDELNKQVSE----------LSQLYKEAQAELEDYRK-RKSLEDIT-----AEYIHkaEHEKLMQltnvsr 684
Cdd:PHA02562 231 TIKAEIEELTDELLNLVMDiedpsaalnkLNTAAAKIKSKIEQFQKvIKMYEKGGvcptcTQQIS--EGPDRIT------ 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 685 aKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITE-------HLQVITTLRTAAKEMEEKISNLKEHLASKEVEV 757
Cdd:PHA02562 303 -KIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLElknkistNKQSLITLVDKAKKVKAAIEELQAEFVDNAEEL 381
|
....*....
gi 966946461 758 AKLEKQLLE 766
Cdd:PHA02562 382 AKLQDELDK 390
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
422-890 |
1.05e-06 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 52.98 E-value: 1.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNT--EISENSSDLSQKLKETQSKYEEAMKEVLSVQkqmk 499
Cdd:PRK01156 163 SLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQiaDDEKSHSITLKEIERLSIEYNNAMDDYNNLK---- 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 500 lglvspesmdnySHLHELRVTEEEINVLKQDLQNA---LEESERNKEKVRELEEKLVEREKGTVIKP--PVEEYEEMKS- 573
Cdd:PRK01156 239 ------------SALNELSSLEDMKNRYESEIKTAesdLSMELEKNNYYKELEERHMKIINDPVYKNrnYINDYFKYKNd 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 574 --SYCSVIENMNKEkaflFEKYqeaqEEIMKlkdtlKSQMTQEASDEAEDMKEAMnrmiDELNKQVSELSQL---YKEAQ 648
Cdd:PRK01156 307 ieNKKQILSNIDAE----INKY----HAIIK-----KLSVLQKDYNDYIKKKSRY----DDLNNQILELEGYemdYNSYL 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 649 AELEDYRKRKSLEDITAEYIHKAEHEKL-MQLTNVSRAKAEdaLSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQ 727
Cdd:PRK01156 370 KSIESLKKKIEEYSKNIERMSAFISEILkIQEIDPDAIKKE--LNEINVKLQDISSKVSSLNQRIRALRENLDELSRNME 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 728 VI----------TTL-----RTAAKEMEEKISNLKEHLASKEVEVAKLE---KQLLEEKAAMTDAMVPRS-SYEKLQSSL 788
Cdd:PRK01156 448 MLngqsvcpvcgTTLgeeksNHIINHYNEKKSRLEEKIREIEIEVKDIDekiVDLKKRKEYLESEEINKSiNEYNKIESA 527
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 789 ESEVSVLA---SKLKESVKEKEKVHSEVAQIRSEVSQVKREK-------------ENIQTLLKSKEQEVNELLQKFQQAQ 852
Cdd:PRK01156 528 RADLEDIKikiNELKDKHDKYEEIKNRYKSLKLEDLDSKRTSwlnalavislidiETNRSRSNEIKKQLNDLESRLQEIE 607
|
490 500 510
....*....|....*....|....*....|....*...
gi 966946461 853 EELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEAL 890
Cdd:PRK01156 608 IGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILI 645
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
423-858 |
1.07e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.46 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 423 IQQLQEILQDLqKRLESSEAERKQLQVELQSRRAELvclnnTEISENSSDLSQKLK--ETQSKYEEAMKEVLSVQKQMKl 500
Cdd:COG4717 70 LKELKELEEEL-KEAEEKEEEYAELQEELEELEEEL-----EELEAELEELREELEklEKLLQLLPLYQELEALEAELA- 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 501 glvspesmDNYSHLHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTvIKPPVEEYEEMKSSycsvIE 580
Cdd:COG4717 143 --------ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEE-LQDLAEELEELQQR----LA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 581 NMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQA----------- 649
Cdd:COG4717 210 ELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVlflvlgllall 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 650 ELEDYRKRKSLEDITAEYIHKAEHEKLMQLtNVSRAKAEDALSEM--KSQYSKVLNELTQLKQLVD--AQKENSVSITEH 725
Cdd:COG4717 290 FLLLAREKASLGKEAEELQALPALEELEEE-ELEELLAALGLPPDlsPEELLELLDRIEELQELLReaEELEEELQLEEL 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 726 LQVITTLRTAAK----EMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSsyeklQSSLESEVSVLASKLKE 801
Cdd:COG4717 369 EQEIAALLAEAGvedeEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALD-----EEELEEELEELEEELEE 443
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 966946461 802 SVKEKEKVHSEVAQIRSEVSQVKrekeniqtllksKEQEVNELLQKFQQAQEELAEM 858
Cdd:COG4717 444 LEEELEELREELAELEAELEQLE------------EDGELAELLQELEELKAELREL 488
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
143-175 |
1.13e-06 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 45.74 E-value: 1.13e-06
10 20 30
....*....|....*....|....*....|....
gi 966946461 143 DGNIPLLLAV-QNGHSEICHFLLDHGADVNSRNK 175
Cdd:pfam00023 1 DGNTPLHLAAgRRGNLEIVKLLLSKGADVNARDK 34
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
422-934 |
1.76e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 52.28 E-value: 1.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVE-------LQSRRAE---LVCLNNTEISENSSDLSQKLKETQSKYEEAMKEV 491
Cdd:TIGR00618 380 HIHTLQQQKTTLTQKLQSLCKELDILQREqatidtrTSAFRDLqgqLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKI 459
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 492 LSVQKQMKLglvsPESMDNYSHLHELRVTEEEINVLKQDLQNALEESERN-KEKVRELEEKLVEREKGTVIKPPVEEYEE 570
Cdd:TIGR00618 460 HLQESAQSL----KEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPlCGSCIHPNPARQDIDNPGPLTRRMQRGEQ 535
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 571 MKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK--SQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQ 648
Cdd:TIGR00618 536 TYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSilTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQH 615
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 649 AELEDYRKRKSLEDITAEYIHKAEHEKLMQLtnvsrAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQv 728
Cdd:TIGR00618 616 ALLRKLQPEQDLQDVRLHLQQCSQELALKLT-----ALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEK- 689
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 729 itTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLleekaamtdamvprssyEKLQSSLESEVSVLASKLKESVKEKEK 808
Cdd:TIGR00618 690 --EQLTYWKEMLAQCQTLLRELETHIEEYDREFNEI-----------------ENASSSLGSDLAAREDALNQSLKELMH 750
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 809 VHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKEvTKLKE 888
Cdd:TIGR00618 751 QARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCE-TLVQE 829
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 966946461 889 ALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKHHQEV 934
Cdd:TIGR00618 830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
579-819 |
2.13e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 50.98 E-value: 2.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 579 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSqmTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYrkrk 658
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAELDALQAELEE--LNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGER---- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 659 sledITAEYIHKAEHEKLMQLTN-------VSRAkaeDALSEMKSQYSKVLNELTQLKQLVDAQKENSVsitehlQVITT 731
Cdd:COG3883 92 ----ARALYRSGGSVSYLDVLLGsesfsdfLDRL---SALSKIADADADLLEELKADKAELEAKKAELE------AKLAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 732 LRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHS 811
Cdd:COG3883 159 LEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
|
....*...
gi 966946461 812 EVAQIRSE 819
Cdd:COG3883 239 AAAAAASA 246
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
422-665 |
2.31e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.92 E-value: 2.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNT--EISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMK 499
Cdd:COG4942 28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRirALEQELAALEAELAELEKEIAELRAELEAQKEELA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 500 LGLVSPESMDNYSHLhELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLverekgtvikppvEEYEEMKSSycsvI 579
Cdd:COG4942 108 ELLRALYRLGRQPPL-ALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADL-------------AELAALRAE----L 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 580 ENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEamnrmIDELNKQVSELSQLYKEAQAELEDYRKRKS 659
Cdd:COG4942 170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAE-----LAELQQEAEELEALIARLEAEAAAAAERTP 244
|
....*.
gi 966946461 660 LEDITA 665
Cdd:COG4942 245 AAGFAA 250
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
741-934 |
2.64e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.60 E-value: 2.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 741 EKISNLKEHLASKEVEVAKLEKQLLEEKaamtdamvprssyeklQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSEV 820
Cdd:TIGR02168 213 ERYKELKAELRELELALLVLRLEELREE----------------LEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 821 SQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEALNslsqlsYST 900
Cdd:TIGR02168 277 SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE------ELK 350
|
170 180 190
....*....|....*....|....*....|....
gi 966946461 901 SSSKRQSQQLEALQQQVKQLQNQLAECKKHHQEV 934
Cdd:TIGR02168 351 EELESLEAELEELEAELEELESRLEELEEQLETL 384
|
|
| PHA02798 |
PHA02798 |
ankyrin-like protein; Provisional |
124-232 |
3.26e-06 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 50.99 E-value: 3.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 124 LQAVQILCEHKSPINLKDLDGNIPLLLAVQN----GHS-EICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEAL-- 196
Cdd:PHA02798 51 TDIVKLFINLGANVNGLDNEYSTPLCTILSNikdyKHMlDIVKILIENGADINKKNSDGETPLYCLLSNGYINNLEILlf 130
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 966946461 197 -IKKGADLNLVDSLGHNALH-YSKLSENAGIQ--SLLLSK 232
Cdd:PHA02798 131 mIENGADTTLLDKDGFTMLQvYLQSNHHIDIEiiKLLLEK 170
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
137-184 |
4.09e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 45.03 E-value: 4.09e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 966946461 137 INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLA 184
Cdd:pfam13857 9 LNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| AAA_13 |
pfam13166 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
412-836 |
4.24e-06 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.
Pssm-ID: 463796 [Multi-domain] Cd Length: 712 Bit Score: 50.83 E-value: 4.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 412 LGKSTTDSDVRIQQLQEILQDLQKRLESSEAE----RKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEA 487
Cdd:pfam13166 87 LGEESIEIQEKIAKLKKEIKDHEEKLDAAEANlqklDKEKEKLEADFLDECWKKIKRKKNSALSEALNGFKYEANFKSRL 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 488 MKEvlsvqkqmklglvspesMDNYSHLHELRVTEEEinvLKQDLQNALEEserNKEKVRELEEKLVEREKgtvikppVEE 567
Cdd:pfam13166 167 LRE-----------------IEKDNFNAGVLLSDED---RKAALATVFSD---NKPEIAPLTFNVIDFDA-------LEK 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 568 YEEMKSS---YCSVIENMNKEKafLFEKYQEAQEEIMK------------LKDTLKSQMTQEASDEAEDMKEAMNRMIDE 632
Cdd:pfam13166 217 AEILIQKvigKSSAIEELIKNP--DLADWVEQGLELHKahldtcpfcgqpLPAERKAALEAHFDDEFTEFQNRLQKLIEK 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 633 LNKQVSELSQLYKEAqaeLEDYRKRKSLEDITAEYihKAEHEKLMQLTNVSRAKAEDALSEMKS--QYSKVLNELTQLKQ 710
Cdd:pfam13166 295 VESAISSLLAQLPAV---SDLASLLSAFELDVEDI--ESEAEVLNSQLDGLRRALEAKRKDPFKsiELDSVDAKIESIND 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 711 LVDAQKEnsvSITEHlqvittlrtaakemEEKISNLKEHLASKEVevaKLEKQLLEEKAAMTDAmvprssYEKLQSSLES 790
Cdd:pfam13166 370 LVASINE---LIAKH--------------NEITDNFEEEKNKAKK---KLRLHLVEEFKSEIDE------YKDKYAGLEK 423
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 966946461 791 EVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKS 836
Cdd:pfam13166 424 AINSLEKEIKNLEAEIKKLREEIKELEAQLRDHKPGADEINKLLKA 469
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
108-151 |
4.38e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 44.64 E-value: 4.38e-06
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 966946461 108 DSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLA 151
Cdd:pfam13857 13 DGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
335-667 |
4.90e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.83 E-value: 4.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 335 ADQQDLLALLQAKVASLtlhNKELQDKLQAKSPKEAEADLSFDSYHSTQTDLGpslgkpgetSPPDSKSSPPVLIHALGK 414
Cdd:TIGR02168 687 EELEEKIAELEKALAEL---RKELEELEEELEQLRKELEELSRQISALRKDLA---------RLEAEVEQLEERIAQLSK 754
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 415 STTDSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELvclnnTEISENSSDLSQKLKETQSKYEEAMKEVLSV 494
Cdd:TIGR02168 755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEEL-----KALREALDELRAELTLLNEEAANLRERLESL 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 495 QKQMKLGLVSPESMDNyshlhELRVTEEEInvlkQDLQNALEESERNKEKV-RELEEKLVEREKGTV-IKPPVEEYEEMK 572
Cdd:TIGR02168 830 ERRIAATERRLEDLEE-----QIEELSEDI----ESLAAEIEELEELIEELeSELEALLNERASLEEaLALLRSELEELS 900
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 573 SSycsvIENMNKEKAFLFEKYQEAQEEIMKLK----------DTLKSQMTQEASDEAEDMKEAMN----------RMIDE 632
Cdd:TIGR02168 901 EE----LRELESKRSELRRELEELREKLAQLElrleglevriDNLQERLSEEYSLTLEEAEALENkieddeeearRRLKR 976
|
330 340 350
....*....|....*....|....*....|....*
gi 966946461 633 LNKQVSELSQLYKEAQAELEDYRKRKslEDITAEY 667
Cdd:TIGR02168 977 LENKIKELGPVNLAAIEEYEELKERY--DFLTAQK 1009
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
513-856 |
6.48e-06 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 50.34 E-value: 6.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 513 HLHELRVTEEEINVLKQDLQNA----LEESERNKEKVRELEEkLVEREKGTvikppVEEYEEMKSSYCSVIENMNkekaf 588
Cdd:PRK04863 277 HANERRVHLEEALELRRELYTSrrqlAAEQYRLVEMARELAE-LNEAESDL-----EQDYQAASDHLNLVQTALR----- 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 589 LFEKYQEAQEEIMKLKDTLKSQM-----TQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDi 663
Cdd:PRK04863 346 QQEKIERYQADLEELEERLEEQNevveeADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALE- 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 664 taeyihkaEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ-LVDAQKENSvsitEHLQVITTLRTAAKEME-- 740
Cdd:PRK04863 425 --------RAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQkLSVAQAAHS----QFEQAYQLVRKIAGEVSrs 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 741 -------------EKISNLKEHLASKEVEVAKLEKQLLEEKAA--MTDAMVPRSSyekLQSSLESEVSVLASKLKESVKE 805
Cdd:PRK04863 493 eawdvarellrrlREQRHLAEQLQQLRMRLSELEQRLRQQQRAerLLAEFCKRLG---KNLDDEDELEQLQEELEARLES 569
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 966946461 806 KEKVHSEVAQIRSEVSQVKREkeniqtlLKSKEQEVNELLQKFQQAQEELA 856
Cdd:PRK04863 570 LSESVSEARERRMALRQQLEQ-------LQARIQRLAARAPAWLAAQDALA 613
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
64-118 |
6.54e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 44.26 E-value: 6.54e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 966946461 64 MVTHG-VDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYA 118
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
614-883 |
7.67e-06 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 48.75 E-value: 7.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 614 EASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYR-KRKSLEDITAEYIHKA-EHEKLMQLTNVSRAKAEDAL 691
Cdd:COG1340 1 SKTDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAeKRDELNAQVKELREEAqELREKRDELNEKVKELKEER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 692 SEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVI--------TTLRTAAKEME--EKISNLKEHLASKEvEVAKLE 761
Cdd:COG1340 81 DELNEKLNELREELDELRKELAELNKAGGSIDKLRKEIerlewrqqTEVLSPEEEKElvEKIKELEKELEKAK-KALEKN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 762 KQLLEEKAAMTDamvprssyeklqssLESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEV 841
Cdd:COG1340 160 EKLKELRAELKE--------------LRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKA 225
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 966946461 842 NELLQKFQQAQEELAEM----KRYSESSSKLEEDKDKKINEMSKEV 883
Cdd:COG1340 226 DELHEEIIELQKELRELrkelKKLRKKQRALKREKEKEELEEKAEE 271
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
516-971 |
1.13e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 516 ELRVTEEeinVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQE 595
Cdd:PTZ00121 1186 EVRKAEE---LRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARM 1262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 596 AQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDITAEYIHKAEHEK 675
Cdd:PTZ00121 1263 AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAK 1342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 676 lmQLTNVSRAKAEDALSEMKSQYSKvlNELTQLKQLVDAQK-ENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE 754
Cdd:PTZ00121 1343 --KAAEAAKAEAEAAADEAEAAEEK--AEAAEKKKEEAKKKaDAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 755 vEVAKLEKQLLEEKAAmtdamvprssyEKLQSSLESEVSvlASKLKESVKEKEKvhSEVAQIRSEvsqvkrEKENIQTLL 834
Cdd:PTZ00121 1419 -KADEAKKKAEEKKKA-----------DEAKKKAEEAKK--ADEAKKKAEEAKK--AEEAKKKAE------EAKKADEAK 1476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 835 KSKEQ--EVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKkinEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEA 912
Cdd:PTZ00121 1477 KKAEEakKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA---EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 966946461 913 LQQQVKQLQNQLAECKKHHQE--VISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQK 971
Cdd:PTZ00121 1554 AEELKKAEEKKKAEEAKKAEEdkNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK 1614
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
417-872 |
1.14e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 49.33 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 417 TDSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLnnTEISENSSDLSQKLKETQSKYEEAMKEVLSVQK 496
Cdd:pfam05483 352 TEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEM--TKFKNNKEVELEELKKILAEDEKLLDEKKQFEK 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 497 QMKlglvspesmdnyshlhELRVTEEEINVLKQDLQNALEESERNKEKVRELEE---KLVEREKGTVIKPPVEEYEEMKS 573
Cdd:pfam05483 430 IAE----------------ELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEhylKEVEDLKTELEKEKLKNIELTAH 493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 574 SYCSVIEN--MNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQeasdeAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL 651
Cdd:pfam05483 494 CDKLLLENkeLTQEASDMTLELKKHQEDIINCKKQEERMLKQ-----IENLEEKEMNLRDELESVREEFIQKGDEVKCKL 568
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 652 EdyrkrKSLEDITAEYIHKAEHEKLMQLTnvsrakaEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITT 731
Cdd:pfam05483 569 D-----KSEENARSIEYEVLKKEKQMKIL-------ENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEI 636
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 732 --------LRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESV 803
Cdd:pfam05483 637 kvnkleleLASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQY 716
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 804 -KEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDK 872
Cdd:pfam05483 717 dKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
542-790 |
1.31e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 49.16 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 542 KEKVRELEEKLVEREKGTVIKPPVEEYEEmksSYCSVIENMNK--EKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEA 619
Cdd:PRK05771 15 KSYKDEVLEALHELGVVHIEDLKEELSNE---RLRKLRSLLTKlsEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 620 EDMKEAMNRMIDELNKQVSEL----SQLYKEAQA---------ELEDYRKRKSLeDITAEYIHKAEHEKLMQLTN----- 681
Cdd:PRK05771 92 EEELEKIEKEIKELEEEISELeneiKELEQEIERlepwgnfdlDLSLLLGFKYV-SVFVGTVPEDKLEELKLESDvenve 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 682 -VSRAKAED-----ALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEH-----L 750
Cdd:PRK05771 171 yISTDKGYVyvvvvVLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKyleelL 250
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 966946461 751 ASKEVEVAKLEKQLLEEKAAMTD------AMVPRSSYEKLQSSLES 790
Cdd:PRK05771 251 ALYEYLEIELERAEALSKFLKTDktfaieGWVPEDRVKKLKELIDK 296
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
294-870 |
1.38e-05 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 49.13 E-value: 1.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 294 KESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLldiSSEADQ-QDLLALLQAKVASLtlhnKELQDKLQAKSPKEAEA 372
Cdd:PRK01156 130 LNSIFVGQGEMDSLISGDPAQRKKILDEILEINSL---ERNYDKlKDVIDMLRAEISNI----DYLEEKLKSSNLELENI 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 373 DLSFDSYHSTQTDLGPSLgKPGETSPPDSKSSPPVLIHALGKSTTDSDVrIQQLQEILQDLQKRLESSEAERKQLQvELQ 452
Cdd:PRK01156 203 KKQIADDEKSHSITLKEI-ERLSIEYNNAMDDYNNLKSALNELSSLEDM-KNRYESEIKTAESDLSMELEKNNYYK-ELE 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 453 SRRAEL----VCLNNTEISE---------NSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSH-LHELR 518
Cdd:PRK01156 280 ERHMKIindpVYKNRNYINDyfkykndieNKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNqILELE 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 519 VTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPP--VEEYEEMKSS---YCSVIENMNKEKAFLFEKY 593
Cdd:PRK01156 360 GYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDaiKKELNEINVKlqdISSKVSSLNQRIRALRENL 439
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 594 QEAQEEIMKLKDTLKSQM------TQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEA--QAELEDYRKRKSLEDITA 665
Cdd:PRK01156 440 DELSRNMEMLNGQSVCPVcgttlgEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIvdLKKRKEYLESEEINKSIN 519
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 666 EY--IHKAEHEKLMQLTNVSRAK-AEDALSEMKSQY---------SKVLNELTQLKQLVDAQKENSVSITEhlQVITTLR 733
Cdd:PRK01156 520 EYnkIESARADLEDIKIKINELKdKHDKYEEIKNRYkslkledldSKRTSWLNALAVISLIDIETNRSRSN--EIKKQLN 597
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 734 TAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLAsKLKESVKEKEKVHSEV 813
Cdd:PRK01156 598 DLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIA-EIDSIIPDLKEITSRI 676
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966946461 814 AQIRSEVSQVKREKENI-------QTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEE 870
Cdd:PRK01156 677 NDIEDNLKKSRKALDDAkanrarlESTIEILRTRINELSDRINDINETLESMKKIKKAIGDLKR 740
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
469-879 |
1.53e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 49.28 E-value: 1.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 469 NSSDLSQKLKETQSKYEeAMKEVLSVQKQMKLGLvspESMDNY------SHLHELRVTEEEIN-VLKQDLQNALEESERN 541
Cdd:TIGR01612 477 GSYDIKKDIDENSKQDN-TVKLILMRMKDFKDII---DFMELYkpdevpSKNIIGFDIDQNIKaKLYKEIEAGLKESYEL 552
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 542 KEKVRELEEKlverekgtvIKPPVEEYEEmkssycSVIEnMNKEKAFLFEKYQEAQEEIM---KLKDTLKSQMtQEASDE 618
Cdd:TIGR01612 553 AKNWKKLIHE---------IKKELEEENE------DSIH-LEKEIKDLFDKYLEIDDEIIyinKLKLELKEKI-KNISDK 615
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 619 AEDMKEAMNRmidelnKQVSELSQLYKEAQAELEDYRkrkslediTAEYIhkaeheklmqltnvsraKAEDAL-SEMKSQ 697
Cdd:TIGR01612 616 NEYIKKAIDL------KKIIENNNAYIDELAKISPYQ--------VPEHL-----------------KNKDKIySTIKSE 664
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 698 YSKVL-NELTQL-KQLVDAQKENSVSITEHlqvittlRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLE-EKAAMTDA 774
Cdd:TIGR01612 665 LSKIYeDDIDALyNELSSIVKENAIDNTED-------KAKLDDLKSKIDKEYDKIQNMETATVELHLSNIEnKKNELLDI 737
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 775 MVprssyeKLQSSLESEVSVLASKLKESVKEKEK-VHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQE 853
Cdd:TIGR01612 738 IV------EIKKHIHGEINKDLNKILEDFKNKEKeLSNKINDYAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQ 811
|
410 420
....*....|....*....|....*.
gi 966946461 854 ELAEMKRYSESSSKLEEDKDKKINEM 879
Cdd:TIGR01612 812 NYDKSKEYIKTISIKEDEIFKIINEM 837
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
143-171 |
1.63e-05 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 42.57 E-value: 1.63e-05
10 20
....*....|....*....|....*....
gi 966946461 143 DGNIPLLLAVQNGHSEICHFLLDHGADVN 171
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADIN 29
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
415-696 |
1.63e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.98 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 415 STTDSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNN----------------TEISENSSDLSQKLK 478
Cdd:COG1340 2 KTDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAqvkelreeaqelrekrDELNEKVKELKEERD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 479 ETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNyshlhelrvTEEEINVLKQDLQNA---LEESERNKEKVRELEEKLVER 555
Cdd:COG1340 82 ELNEKLNELREELDELRKELAELNKAGGSIDK---------LRKEIERLEWRQQTEvlsPEEEKELVEKIKELEKELEKA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 556 EKGTVIKppvEEYEEMKSSYCSVIENMNKekafLFEKYQEAQEEIMKLKDTLksqmtQEASDEAEDMKE---AMNRMIDE 632
Cdd:COG1340 153 KKALEKN---EKLKELRAELKELRKEAEE----IHKKIKELAEEAQELHEEM-----IELYKEADELRKeadELHKEIVE 220
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966946461 633 LNKQVSELSQLYKEAQAELEDYRKRKSLEDITAEYIHKAEHEKLMqltnvsRAKAEDALSEMKS 696
Cdd:COG1340 221 AQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEEL------EEKAEEIFEKLKK 278
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
651-891 |
1.64e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 48.77 E-value: 1.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 651 LEDYRKRkslediTAEYIHKaehEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQK-----ENSVSITEH 725
Cdd:PRK05771 14 LKSYKDE------VLEALHE---LGVVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNplreeKKKVSVKSL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 726 LQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKaamtdamvprsSYEKLQSSLESE-----VSVLASKLK 800
Cdd:PRK05771 85 EELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLE-----------PWGNFDLDLSLLlgfkyVSVFVGTVP 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 801 ESVKEKEKVHSEVaqirsEVSQVKREKENIQTL----LKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEdkdkKI 876
Cdd:PRK05771 154 EDKLEELKLESDV-----ENVEYISTDKGYVYVvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKE----EL 224
|
250
....*....|....*
gi 966946461 877 NEMSKEVTKLKEALN 891
Cdd:PRK05771 225 EEIEKERESLLEELK 239
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
422-717 |
2.18e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 48.80 E-value: 2.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVclnNTEISENS-----SDLSQKLKETQSK---YEEAMKEVLS 493
Cdd:COG3096 348 KIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLE---AAEEEVDSlksqlADYQQALDVQQTRaiqYQQAVQALEK 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 494 VQKQMKLGLVSPESMDNYshLHELRVTEEEIN----VLKQDLQNAlEESERNKEKVRELEEKL---VEREK-GTVIKPPV 565
Cdd:COG3096 425 ARALCGLPDLTPENAEDY--LAAFRAKEQQATeevlELEQKLSVA-DAARRQFEKAYELVCKIageVERSQaWQTARELL 501
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 566 EEYeemkSSYCSVIENMNKEKAFLFEKYQ--EAQEEIMKLKDTLKSQMTQE--ASDEAEDMKEAMNRMIDELNKQVSELS 641
Cdd:COG3096 502 RRY----RSQQALAQRLQQLRAQLAELEQrlRQQQNAERLLEEFCQRIGQQldAAEELEELLAELEAQLEELEEQAAEAV 577
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966946461 642 QLYKEAQAELEDYR-KRKSLEDITAEYIHKAEH-EKLMQLTNVSRAKAEDALSEMKSQYSKvLNELTQLKQLVDAQKE 717
Cdd:COG3096 578 EQRSELRQQLEQLRaRIKELAARAPAWLAAQDAlERLREQSGEALADSQEVTAAMQQLLER-EREATVERDELAARKQ 654
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
27-85 |
2.19e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 42.72 E-value: 2.19e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 966946461 27 ARRGPAPPNTTararPRKLKHCFHLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLA 85
Cdd:pfam13857 2 LEHGPIDLNRL----DGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PHA02798 |
PHA02798 |
ankyrin-like protein; Provisional |
59-232 |
3.03e-05 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 47.52 E-value: 3.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 59 ECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHH---ECIRKLLQSKCPAESVDSS-GKTALHyaaaqgclqavqilCEHK 134
Cdd:PHA02798 126 EILLFMIENGADTTLLDKDGFTMLQVYLQSNHHidiEIIKLLLEKGVDINTHNNKeKYDTLH--------------CYFK 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 135 SPINLKDLDgniplllavqnghseICHFLLDHGADVNSRNKSGRTALM-------LACEIGSSNVVEaLIKKGADLNLVD 207
Cdd:PHA02798 192 YNIDRIDAD---------------ILKLFVDNGFIINKENKSHKKKFMeylnsllYDNKRFKKNILD-FIFSYIDINQVD 255
|
170 180
....*....|....*....|....*
gi 966946461 208 SLGHNALHYSKLSENAGIQSLLLSK 232
Cdd:PHA02798 256 ELGFNPLYYSVSHNNRKIFEYLLQL 280
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
177-207 |
3.33e-05 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 41.51 E-value: 3.33e-05
10 20 30
....*....|....*....|....*....|..
gi 966946461 177 GRTALMLACEI-GSSNVVEALIKKGADLNLVD 207
Cdd:pfam00023 2 GNTPLHLAAGRrGNLEIVKLLLSKGADVNARD 33
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
177-204 |
3.57e-05 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 41.47 E-value: 3.57e-05
10 20
....*....|....*....|....*...
gi 966946461 177 GRTALMLACEIGSSNVVEALIKKGADLN 204
Cdd:pfam13606 2 GNTPLHLAARNGRLEIVKLLLENGADIN 29
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
633-891 |
5.37e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 47.23 E-value: 5.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 633 LNKQVSE-LSQLYKEAQAELEDYRkrkslEDITAEYIHKAEHEklmqltnvsRAKAEDALSEMKSqYSKVLNELTQLKQL 711
Cdd:PRK05771 14 LKSYKDEvLEALHELGVVHIEDLK-----EELSNERLRKLRSL---------LTKLSEALDKLRS-YLPKLNPLREEKKK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 712 VDAQKENSV--SITEHLQVIttlRTAAKEMEEKISNLKEHLASKEVEVAKLE---------KQLLEEK-AAMTDAMVPRS 779
Cdd:PRK05771 79 VSVKSLEELikDVEEELEKI---EKEIKELEEEISELENEIKELEQEIERLEpwgnfdldlSLLLGFKyVSVFVGTVPED 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 780 SYEKLQSSLESEVSVLASKLKESV-------KEKEKVHSEV---------------------AQIRSEVSQVKREKENIQ 831
Cdd:PRK05771 156 KLEELKLESDVENVEYISTDKGYVyvvvvvlKELSDEVEEElkklgferleleeegtpseliREIKEELEEIEKERESLL 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966946461 832 TLLKSKEQEVNELLqkfQQAQEELAEMKRYSESSSKLEEDKDKKINE---MSKEVTKLKEALN 891
Cdd:PRK05771 236 EELKELAKKYLEEL---LALYEYLEIELERAEALSKFLKTDKTFAIEgwvPEDRVKKLKELID 295
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
177-205 |
5.59e-05 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 41.03 E-value: 5.59e-05
10 20
....*....|....*....|....*....
gi 966946461 177 GRTALMLACEIGSSNVVEALIKKGADLNL 205
Cdd:smart00248 2 GRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
40-170 |
6.10e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 46.98 E-value: 6.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 40 ARPRKLKHCFHLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSH-HECIRKLLQSKCPAESVDSSGKTALHYA 118
Cdd:PHA02876 370 ARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFALCGTNpYMSVKTLIDRGANVNSKNKDLSTPLHYA 449
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 966946461 119 AAQGC-LQAVQILCEHKSPINLKDLDGNIPLLLAVqnGHSEICHFLLDHGADV 170
Cdd:PHA02876 450 CKKNCkLDVIEMLLDNGADVNAINIQNQYPLLIAL--EYHGIVNILLHYGAEL 500
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
613-858 |
6.59e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 6.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 613 QEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKR-----KSLEDITAEYihkAEHEKLMQLTNVSRAKA 687
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiaalaRRIRALEQEL---AALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 688 EDALSEMKSQYSKVLNELTQLKQLVDAQ-KENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLAskevEVAKLEKQLLE 766
Cdd:COG4942 96 RAELEAQKEELAELLRALYRLGRQPPLAlLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA----ELAALRAELEA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 767 EKaamtdamvprssyeklqsslesevsvlasklkesvKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQ 846
Cdd:COG4942 172 ER-----------------------------------AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELA 216
|
250
....*....|..
gi 966946461 847 KFQQAQEELAEM 858
Cdd:COG4942 217 ELQQEAEELEAL 228
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
458-721 |
6.76e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 6.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 458 LVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNyshlhELRVTEEEINVLKQDLQNALEE 537
Cdd:COG4942 10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER-----RIAALARRIRALEQELAALEAE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 538 SERNKEKVRELEEKLVEREkgtvikppvEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASD 617
Cdd:COG4942 85 LAELEKEIAELRAELEAQK---------EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 618 EAEdmKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRksleditaeyihKAEHEKLMQLTNVSRAKAEDALSEMKSQ 697
Cdd:COG4942 156 RAD--LAELAALRAELEAERAELEALLAELEEERAALEAL------------KAERQKLLARLEKELAELAAELAELQQE 221
|
250 260
....*....|....*....|....
gi 966946461 698 YSKVLNELTQLKQLVDAQKENSVS 721
Cdd:COG4942 222 AEELEALIARLEAEAAAAAERTPA 245
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
422-891 |
6.83e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.83 E-value: 6.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 422 RIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNtEISENSSD----LSQKLKETQSKYEEAMKEVLSVQKQ 497
Cdd:COG4913 289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEA-QIRGNGGDrleqLEREIERLERELEERERRRARLEAL 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 498 MK-LGLVSPESMDNYSHLH-ELRVTEEEINVLKQDLQNALEESERNKEKVR-ELEEKLVERE----KGTVIkPPveEYEE 570
Cdd:COG4913 368 LAaLGLPLPASAEEFAALRaEAAALLEALEEELEALEEALAEAEAALRDLRrELRELEAEIAslerRKSNI-PA--RLLA 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 571 MKSSYCSVIENMNKEKAFL----------------FEK---------------YQEAQEEI-----------MKLKDTLK 608
Cdd:COG4913 445 LRDALAEALGLDEAELPFVgelievrpeeerwrgaIERvlggfaltllvppehYAAALRWVnrlhlrgrlvyERVRTGLP 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 609 SQMTQEASDE--AEDMKEAMNRMIDELNKQVSELSQLYK-EAQAELEDYRKRksledITAE---YIHKAEHEKLMQLTNV 682
Cdd:COG4913 525 DPERPRLDPDslAGKLDFKPHPFRAWLEAELGRRFDYVCvDSPEELRRHPRA-----ITRAgqvKGNGTRHEKDDRRRIR 599
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 683 SR----AKAEDALSEMKSQYSKVLNELTQLKQLVDAqkensvsITEHLQVITTLRTAAKEMEEKISNLKEhLASKEVEVA 758
Cdd:COG4913 600 SRyvlgFDNRAKLAALEAELAELEEELAEAEERLEA-------LEAELDALQERREALQRLAEYSWDEID-VASAEREIA 671
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 759 KLEKQLleekaamtdamvprssyEKLQSSlESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKE 838
Cdd:COG4913 672 ELEAEL-----------------ERLDAS-SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ 733
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 966946461 839 QEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKInemSKEVTKLKEALN 891
Cdd:COG4913 734 DRLEAAEDLARLELRALLEERFAAALGDAVERELRENL---EERIDALRARLN 783
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
122-206 |
7.82e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 46.11 E-value: 7.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 122 GCLQAVQILCEHKSP-INLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKG 200
Cdd:PHA02874 12 GDIEAIEKIIKNKGNcINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIDNG 91
|
....*.
gi 966946461 201 ADLNLV 206
Cdd:PHA02874 92 VDTSIL 97
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
591-865 |
7.93e-05 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 46.99 E-value: 7.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 591 EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAM---NRMIDELN--KQVSEL--SQLYKEAQAELEDYRKRKSLEDI 663
Cdd:COG5022 810 KEYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEvliQKFGRSLKakKRFSLLkkETIYLQSAQRVELAERQLQELKI 889
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 664 TAEyihKAEHEKLMQLTNVSRakaedaLSEMKSQYSKVLNELTQLKqlvdaqkensvsiTEHlqvITTLRTAAKEMEEKI 743
Cdd:COG5022 890 DVK---SISSLKLVNLELESE------IIELKKSLSSDLIENLEFK-------------TEL---IARLKKLLNNIDLEE 944
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 744 SnlkehlASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLK-----------------ESVKEK 806
Cdd:COG5022 945 G------PSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKnfkkelaelskqygalqESTKQL 1018
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 966946461 807 EKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEvNELLQKFQQAQEELAEMKRYSESS 865
Cdd:COG5022 1019 KELPVEVAELQSASKIISSESTELSILKPLQKLK-GLLLLENNQLQARYKALKLRRENS 1076
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
589-763 |
8.16e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.83 E-value: 8.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 589 LFEKYQEAQEEIMK---LKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKS------ 659
Cdd:COG4913 260 LAERYAAARERLAEleyLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRgnggdr 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 660 LEDITAEyIHKAEHEKlmQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEhlqvitTLRTAAKEM 739
Cdd:COG4913 340 LEQLERE-IERLEREL--EERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE------ALEEALAEA 410
|
170 180
....*....|....*....|....
gi 966946461 740 EEKISNLKEHLASKEVEVAKLEKQ 763
Cdd:COG4913 411 EAALRDLRRELRELEAEIASLERR 434
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
53-133 |
1.34e-04 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 45.66 E-value: 1.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 53 AAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCE 132
Cdd:PTZ00322 90 AASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSR 169
|
.
gi 966946461 133 H 133
Cdd:PTZ00322 170 H 170
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
465-890 |
1.57e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.88 E-value: 1.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 465 EISENSSDLSQKLKETQSKYEEAM----KEVLSVQKQMKLGLVSPESMdnyshlHELRVTEEEInvlKQDLQNALEESER 540
Cdd:pfam15921 82 EYSHQVKDLQRRLNESNELHEKQKfylrQSVIDLQTKLQEMQMERDAM------ADIRRRESQS---QEDLRNQLQNTVH 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 541 NKEKVRELEEKLVEREKGTVikppvEEYEEMKSSYCSVIENMNKekafLFEKYQEAQEEIMKLKDTLKSQmtqeasdEAE 620
Cdd:pfam15921 153 ELEAAKCLKEDMLEDSNTQI-----EQLRKMMLSHEGVLQEIRS----ILVDFEEASGKKIYEHDSMSTM-------HFR 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 621 DMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYrkrKSLEDITAEYIHKAEHEKLMQLtnVSRAKAE-DALSEMKSQYS 699
Cdd:pfam15921 217 SLGSAISKILRELDTEISYLKGRIFPVEDQLEAL---KSESQNKIELLLQQHQDRIEQL--ISEHEVEiTGLTEKASSAR 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 700 KVLNELTQLKQLVDAQKENSVSIteHLQVITTLRTAAKEMEekiSNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRS 779
Cdd:pfam15921 292 SQANSIQSQLEIIQEQARNQNSM--YMRQLSDLESTVSQLR---SELREAKRMYEDKIEELEKQLVLANSELTEARTERD 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 780 SYEKLQSSLESEVSVLASKL----KESVKEKEKVHS----------EVAQIRSEVSQVKREKENIQTLLKSKEQEVN-EL 844
Cdd:pfam15921 367 QFSQESGNLDDQLQKLLADLhkreKELSLEKEQNKRlwdrdtgnsiTIDHLRRELDDRNMEVQRLEALLKAMKSECQgQM 446
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 966946461 845 LQKFQQAQEELAEMKRYSESSSKLEEDKDkKINEMSKEVTKLKEAL 890
Cdd:pfam15921 447 ERQMAAIQGKNESLEKVSSLTAQLESTKE-MLRKVVEELTAKKMTL 491
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
426-891 |
1.64e-04 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 45.84 E-value: 1.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 426 LQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLN-NTEISENSSDLSQKLKET---QSKYEEAMKEVLSVQKQMKLG 501
Cdd:COG5022 799 LQPLLSLLGSRKEYRSYLACIIKLQKTIKREKKLRETeEVEFSLKAEVLIQKFGRSlkaKKRFSLLKKETIYLQSAQRVE 878
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 502 LVSPESMD------NYSHLHELRVT-EEEINVLKQDLQNAL-EESERNKEKVRELEEKL------VEREKGTVIKPPVEE 567
Cdd:COG5022 879 LAERQLQElkidvkSISSLKLVNLElESEIIELKKSLSSDLiENLEFKTELIARLKKLLnnidleEGPSIEYVKLPELNK 958
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 568 YEEMKSSY---CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMKEAMNRMIDELNKQVSELSQL 643
Cdd:COG5022 959 LHEVESKLketSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQyGALQESTKQLKELPVEVAELQSASKIISSE 1038
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 644 YKEAQAEL-EDYRKRKSLEDITAeyiHKAEHEKLMQltnvsRAKAEDALSEMKSQYSKVLNELTQLKQL-VDAQKENSVS 721
Cdd:COG5022 1039 STELSILKpLQKLKGLLLLENNQ---LQARYKALKL-----RRENSLLDDKQLYQLESTENLLKTINVKdLEVTNRNLVK 1110
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 722 ITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEK-QLLEEKAAMTDAMVPRSSYEKLQSSLESEvSVLASKLK 800
Cdd:COG5022 1111 PANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVlQLELDGLFWEANLEALPSPPPFAALSEKR-LYQSALYD 1189
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 801 ESVKEKekvHSEVAQIRSEVSqvkrekeniqtLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMS 880
Cdd:COG5022 1190 EKSKLS---SSEVNDLKNELI-----------ALFSKIFSGWPRGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPAS 1255
|
490
....*....|.
gi 966946461 881 KEVTKLKEALN 891
Cdd:COG5022 1256 MSNEKLLSLLN 1266
|
|
| trp |
TIGR00870 |
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ... |
46-188 |
1.76e-04 |
|
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 45.46 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 46 KHCFHlAAAKGHV----ECLRVMVTHGVD------VTAQDTT----GHSALHLAAKNSHHECIRKLLQSK-------CPA 104
Cdd:TIGR00870 83 DTLLH-AISLEYVdaveAILLHLLAAFRKsgplelANDQYTSeftpGITALHLAAHRQNYEIVKLLLERGasvparaCGD 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 105 ESVDSSGKTALHY-------AAAQGCLQAVQILCEHKSPINLKDLDGNIPL-LLAVQNGHSE-----ICH---FLLDHGA 168
Cdd:TIGR00870 162 FFVKSQGVDSFYHgesplnaAACLGSPSIVALLSEDPADILTADSLGNTLLhLLVMENEFKAeyeelSCQmynFALSLLD 241
|
170 180
....*....|....*....|....*..
gi 966946461 169 DVNS-------RNKSGRTALMLACEIG 188
Cdd:TIGR00870 242 KLRDskeleviLNHQGLTPLKLAAKEG 268
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
471-699 |
1.83e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.82 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 471 SDLSQKLKETQSKYEEAMKEVLSVQKQMKlglvspesmdnyshlhelrVTEEEINVLKQDLQNALEESERNKEKVRELEE 550
Cdd:COG3883 19 QAKQKELSELQAELEAAQAELDALQAELE-------------------ELNEEYNELQAELEALQAEIDKLQAEIAEAEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 551 KLVEREkgtvikppvEEYEE-MKSSY------------------------CSVIENMNKEKAFLFEKYQEAQEEIMKLKD 605
Cdd:COG3883 80 EIEERR---------EELGErARALYrsggsvsyldvllgsesfsdfldrLSALSKIADADADLLEELKADKAELEAKKA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 606 TLKSQMtqeasDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDITAEYIHKAEHEKLMQLTNVSRA 685
Cdd:COG3883 151 ELEAKL-----AELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
|
250
....*....|....
gi 966946461 686 KAEDALSEMKSQYS 699
Cdd:COG3883 226 AAAAAAAAAAAAAA 239
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
512-858 |
1.91e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 45.12 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 512 SHLHELRVTEEEINVLKQDLQnalEESERNKE---KVRELEEKLVEREKGTvikppvEEYEEMKSSYCSVIENMNKEKAF 588
Cdd:pfam05557 24 EHKRARIELEKKASALKRQLD---RESDRNQElqkRIRLLEKREAEAEEAL------REQAELNRLKKKYLEALNKKLNE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 589 LFEKYQEAQEEIMKLKDTL-----KSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQA---ELEDYRKR-KS 659
Cdd:pfam05557 95 KESQLADAREVISCLKNELselrrQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKqqsSLAEAEQRiKE 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 660 LEDITAEYIHKAEHEKLMQ--LTNVSRAKAE-DALSEMKSQYSK------VLNE-----LTQLKQLVDAQKENSVSITEH 725
Cdd:pfam05557 175 LEFEIQSQEQDSEIVKNSKseLARIPELEKElERLREHNKHLNEnienklLLKEevedlKRKLEREEKYREEAATLELEK 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 726 LQVITTLRTAAKEMEEKISNLK--EHLASKEVEVAKLEKQLLEEKAAMTDAMvprSSYEKLQSSLESEVSVLASKLKESV 803
Cdd:pfam05557 255 EKLEQELQSWVKLAQDTGLNLRspEDLSRRIEQLQQREIVLKEENSSLTSSA---RQLEKARRELEQELAQYLKKIEDLN 331
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 966946461 804 KEKEKVHSEVAQIRSEVSQVKREKENIQTLLKS--KEQEVNELLQKFQQAQEELAEM 858
Cdd:pfam05557 332 KKLKRHKALVRRLQRRVLLLTKERDGYRAILESydKELTMSNYSPQLLERIEEAEDM 388
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
541-934 |
2.20e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.52 E-value: 2.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 541 NKEKVRELEEK------LVEREkgtVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKyqeaqeEIMKLKDTLKSQMTQE 614
Cdd:PTZ00121 1025 NIEKIEELTEYgnnddvLKEKD---IIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDF------DFDAKEDNRADEATEE 1095
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 615 ASDEAEDMKEAMNRMIDELNKQvselsqlyKEAQAELEDYRK----RKSLEDITAEYIHKAEHEKLMQLTNvsraKAEDA 690
Cdd:PTZ00121 1096 AFGKAEEAKKTETGKAEEARKA--------EEAKKKAEDARKaeeaRKAEDARKAEEARKAEDAKRVEIAR----KAEDA 1163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 691 LSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAakEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA 770
Cdd:PTZ00121 1164 RKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKA--EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 771 MTDAMVPRSSYEKLQssLESEVSVLASKLKESVKEKEKVHSEvaqirsEVSQVKrEKENIQTLLKSKE-QEVNELLQKfq 849
Cdd:PTZ00121 1242 AKKAEEERNNEEIRK--FEEARMAHFARRQAAIKAEEARKAD------ELKKAE-EKKKADEAKKAEEkKKADEAKKK-- 1310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 850 qaqeelAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEALN-SLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK 928
Cdd:PTZ00121 1311 ------AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEaAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAK 1384
|
....*.
gi 966946461 929 KHHQEV 934
Cdd:PTZ00121 1385 KKAEEK 1390
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
412-655 |
2.33e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.01 E-value: 2.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 412 LGKSTTDSDVRIQQLQEILQDLQKRLESSEAERKQLQvelqsRRAELVCLNNTE--ISENSSDLSQKLKETQSKYEEAMK 489
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAklLLQQLSELESQLAEARAELAEAEA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 490 EVLSVQKQMKLGLVSPESMDNYSHLHELRvteEEINVLKQDLQNALEESERNKEKVRELEEKLVEREkgtvikppveeyE 569
Cdd:COG3206 241 RLAALRAQLGSGPDALPELLQSPVIQQLR---AQLAELEAELAELSARYTPNHPDVIALRAQIAALR------------A 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 570 EMKSSYCSVIENMNKEKAFLfekyQEAQEEIMKLKDTLKSQMTQEASDEAEdmkeamnrmIDELNKQVSELSQLYKEAQA 649
Cdd:COG3206 306 QLQQEAQRILASLEAELEAL----QAREASLQAQLAQLEARLAELPELEAE---------LRRLEREVEVARELYESLLQ 372
|
....*.
gi 966946461 650 ELEDYR 655
Cdd:COG3206 373 RLEEAR 378
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
535-874 |
2.93e-04 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 44.85 E-value: 2.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 535 LEESERNKEKVRELE---EKLVE---REKGTVIKPPVEEYEEMkssycsvIENMNKEkafLFEKYQEAQEEiMKLKDTLk 608
Cdd:PLN03229 421 MKKREAVKTPVRELEgevEKLKEqilKAKESSSKPSELALNEM-------IEKLKKE---IDLEYTEAVIA-MGLQERL- 488
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 609 sQMTQEASDEAEDMKEAMNRMIDElnkQVSELSQLYKEAQAELEDYRKRKSleditaeyihkaeheKLMQLTNVSRAKAe 688
Cdd:PLN03229 489 -ENLREEFSKANSQDQLMHPVLME---KIEKLKDEFNKRLSRAPNYLSLKY---------------KLDMLNEFSRAKA- 548
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 689 daLSEMKSQYSKVLNELTQ-LKQLVDA----QKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLaskEVEVAKLEKQ 763
Cdd:PLN03229 549 --LSEKKSKAEKLKAEINKkFKEVMDRpeikEKMEALKAEVASSGASSGDELDDDLKEKVEKMKKEI---ELELAGVLKS 623
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 764 LLEEKAAMTDAMVPRSSY---EKLQSSLESEVSVLASKLKESVKEKEkVHSEVAQIRSEVSQVKR-----EKENIQTLLK 835
Cdd:PLN03229 624 MGLEVIGVTKKNKDTAEQtppPNLQEKIESLNEEINKKIERVIRSSD-LKSKIELLKLEVAKASKtpdvtEKEKIEALEQ 702
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 966946461 836 SKEQEV------NELLQKFQQAQEELAEMKRYSESSS-KLEEDKDK 874
Cdd:PLN03229 703 QIKQKIaealnsSELKEKFEELEAELAAARETAAESNgSLKNDDDK 748
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
132-243 |
3.28e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 44.27 E-value: 3.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 132 EHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSS-----NVVEALIKKGADLNLV 206
Cdd:PHA03100 23 MEDDLNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHYLSNIKYNltdvkEIVKLLLEYGANVNAP 102
|
90 100 110
....*....|....*....|....*....|....*....
gi 966946461 207 DSLGHNALHY--SKLSENAGIQSLLLSKISqDADLKTPT 243
Cdd:PHA03100 103 DNNGITPLLYaiSKKSNSYSIVEYLLDNGA-NVNIKNSD 140
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
424-647 |
3.56e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 44.67 E-value: 3.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 424 QQLQEILQDLQKRLESSEAERKQLQvELQSRRAELvclnNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKlglv 503
Cdd:PRK03918 528 EKLKEKLIKLKGEIKSLKKELEKLE-ELKKKLAEL----EKKLDELEEELAELLKELEELGFESVEELEERLKELE---- 598
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 504 spESMDNYSHL----HELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKgtviKPPVEEYEEMKSSYCSVI 579
Cdd:PRK03918 599 --PFYNEYLELkdaeKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK----KYSEEEYEELREEYLELS 672
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 580 ENMNKEKAFLfEKYQEAQEEIMKLKDTLKSQMT--QEASDEAEDMKEAMNRMiDELNKQVSELSQLYKEA 647
Cdd:PRK03918 673 RELAGLRAEL-EELEKRREEIKKTLEKLKEELEerEKAKKELEKLEKALERV-EELREKVKKYKALLKER 740
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
459-887 |
3.85e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 44.66 E-value: 3.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 459 VCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMK--------------------LGLVSPESMDNyshlhELR 518
Cdd:TIGR01612 925 ICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKdkfdntlidkineldkafkdASLNDYEAKNN-----ELI 999
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 519 vteEEINVLKQDL----QNALEESERNKEK-VRELEEKLVEREKG---------TVIKPPVEEYEE-----MKSSYCSVI 579
Cdd:TIGR01612 1000 ---KYFNDLKANLgknkENMLYHQFDEKEKaTNDIEQKIEDANKNipnieiaihTSIYNIIDEIEKeigknIELLNKEIL 1076
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 580 ENMN---------KEKA-------FLFEKYQEAQEEIMKLKDTLKS--QMTQEASDEAEDMKEAMNRMIDELNKQVSELS 641
Cdd:TIGR01612 1077 EEAEinitnfneiKEKLkhynfddFGKEENIKYADEINKIKDDIKNldQKIDHHIKALEEIKKKSENYIDEIKAQINDLE 1156
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 642 QLYKEAQAELEDYRKRKSLEDITA-----EYIHKAEHEKLMQLTNVSRAKAedALSEMKS---QYSKVLNELtqLKQLVD 713
Cdd:TIGR01612 1157 DVADKAISNDDPEEIEKKIENIVTkidkkKNIYDEIKKLLNEIAEIEKDKT--SLEEVKGinlSYGKNLGKL--FLEKID 1232
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 714 AQKENSvsitEHLqvittlrtaAKEMEEKISNLKEhLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQS------- 786
Cdd:TIGR01612 1233 EEKKKS----EHM---------IKAMEAYIEDLDE-IKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIiskkhde 1298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 787 ----------------SLESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKR--EKENIQTLLKSKEQEVNELLQKF 848
Cdd:TIGR01612 1299 nisdirekslkiiedfSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNilKLNKIKKIIDEVKEYTKEIEENN 1378
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 966946461 849 QQAQEELAE----MKRYSESSSkLEEDK--------DKKINEMSKEVTKLK 887
Cdd:TIGR01612 1379 KNIKDELDKseklIKKIKDDIN-LEECKskiestldDKDIDECIKKIKELK 1428
|
|
| CAGE1 |
pfam15066 |
Cancer-associated gene protein 1 family; CAGE-1 is a family of proteins overexpressed in ... |
418-557 |
4.23e-04 |
|
Cancer-associated gene protein 1 family; CAGE-1 is a family of proteins overexpressed in tumour tissues compared with surrounding tissues. CAGE-1 gene showed testis-specific expression among normal tissues and displayed wide expression in a variety of cancer cell lines and cancer tissues. CAGE-1 is predominantly expressed during post-meiotic stages. It localizes to the acrosomal matrix and acrosomal granule showing it to be a component of the acrosome of mammalian spermatids and spermatozoa.
Pssm-ID: 464481 Cd Length: 528 Bit Score: 44.05 E-value: 4.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 418 DSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNN---TEISENSSDLSQKLK--ETQSKYEEamkEVL 492
Cdd:pfam15066 388 DINKTLQNLQEILANTQKHLQESRKEKETLQLELKKIKVNYVHLQEryiTEMQQKNKSVSQCLEmdKTLSKKEE---EVE 464
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966946461 493 SVQkQMKLGL--VSPESMDNYSHLHELRvtEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREK 557
Cdd:pfam15066 465 RLQ-QLKGELekATTSALDLLKREKETR--EQEFLSLQEEFQKHEKENLEERQKLKSRLEKLVAQVK 528
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
412-674 |
4.65e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.14 E-value: 4.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 412 LGKSTTDsdvRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNteiSENSSDLSQKLKETQSKYEEAMKEV 491
Cdd:COG4913 604 LGFDNRA---KLAALEAELAELEEELAEAEERLEALEAELDALQERREALQR---LAEYSWDEIDVASAEREIAELEAEL 677
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 492 LSVQKqmklglvspeSMDnyshlhELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREkgtvikppvEEYEEM 571
Cdd:COG4913 678 ERLDA----------SSD------DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAE---------EELDEL 732
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 572 KSSYCSVIENMNKEKAFLFEKYQEAQeeimkLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL 651
Cdd:COG4913 733 QDRLEAAEDLARLELRALLEERFAAA-----LGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADL 807
|
250 260 270
....*....|....*....|....*....|
gi 966946461 652 -------EDYRKRksLEDITAEYIHKAEHE 674
Cdd:COG4913 808 dadleslPEYLAL--LDRLEEDGLPEYEER 835
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
412-860 |
4.83e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.01 E-value: 4.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 412 LGKSTTDSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELvclnnteisensSDLSQKLKETQSKYEEAMKEV 491
Cdd:pfam01576 396 LQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSEL------------ESVSSLLNEAEGKNIKLSKDV 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 492 LSVQKQMK--LGLVSPESMDNYSHLHELRVTEEEINVLKQDLQNAlEESERNKEK-VRELEEKLVE-REKGTVIKPPVEE 567
Cdd:pfam01576 464 SSLESQLQdtQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEE-EEAKRNVERqLSTLQAQLSDmKKKLEEDAGTLEA 542
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 568 YEEMKSSYCSVIENMN---KEKAFLFEKYQEA----QEEIMKLKDTLKSQMT--------------------------QE 614
Cdd:pfam01576 543 LEEGKKRLQRELEALTqqlEEKAAAYDKLEKTknrlQQELDDLLVDLDHQRQlvsnlekkqkkfdqmlaeekaisaryAE 622
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 615 ASDEAE-DMKE------AMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKsleDITAEYIHKAEHeklmqltnvSRAKA 687
Cdd:pfam01576 623 ERDRAEaEAREketralSLARALEEALEAKEELERTNKQLRAEMEDLVSSK---DDVGKNVHELER---------SKRAL 690
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 688 EDALSEMKSQYSKVLNELTQLKqlvDAQkensvsitehLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAK----LEKQ 763
Cdd:pfam01576 691 EQQVEEMKTQLEELEDELQATE---DAK----------LRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKqvreLEAE 757
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 764 LLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNE 843
Cdd:pfam01576 758 LEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKN 837
|
490
....*....|....*..
gi 966946461 844 LLQKFQQAQEELAEMKR 860
Cdd:pfam01576 838 LEAELLQLQEDLAASER 854
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
418-840 |
5.73e-04 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 43.88 E-value: 5.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 418 DSDVRIQQ---LQEILQDL-QKRLESSEaERKQLQVELQSRRAELvcLNNT-----EISENSSDLSQKLKetqskyeeam 488
Cdd:PTZ00108 967 DENGKIKKysdALDILKEFyLVRLDLYK-KRKEYLLGKLERELAR--LSNKvrfikHVINGELVITNAKK---------- 1033
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 489 KEVLSVQKqmKLGLVSpesMDNYSHLHELRVTEEEINVLKQDLQNALEESERN-------------------KEKVRELE 549
Cdd:PTZ00108 1034 KDLVKELK--KLGYVR---FKDIIKKKSEKITAEEEEGAEEDDEADDEDDEEElgaavsydyllsmpiwsltKEKVEKLN 1108
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 550 EKLVEREKgtvikppveEYEEMKSsycSVIENMNKekaflfekyqeaqEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRM 629
Cdd:PTZ00108 1109 AELEKKEK---------ELEKLKN---TTPKDMWL-------------EDLDKFEEALEEQEEVEEKEIAKEQRLKSKTK 1163
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 630 IDELNKQVSELSQLyKEAQAELEDYRKRKSLEDITAEYIHKAEHEKLMQLTNVSRAKAEDalsemKSQYSKVLNELTQLK 709
Cdd:PTZ00108 1164 GKASKLRKPKLKKK-EKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSG-----SDQEDDEEQKTKPKK 1237
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 710 QLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAamTDAMVPRSSYEKLQSSLE 789
Cdd:PTZ00108 1238 SSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESN--GGSKPSSPTKKKVKKRLE 1315
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 966946461 790 SEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQE 840
Cdd:PTZ00108 1316 GSLAALKKKKKSEKKTARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSE 1366
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
582-860 |
6.30e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 6.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 582 MNKEKAF-LFEKYQEAQEeIMKLKDTLKSQMTqeasdEAEDMKEAmnrmIDELNKQVSELSQLYKEAqaeLEDYRKRKSL 660
Cdd:COG4913 188 IGSEKALrLLHKTQSFKP-IGDLDDFVREYML-----EEPDTFEA----ADALVEHFDDLERAHEAL---EDAREQIELL 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 661 EDITAEY-------IHKAEHEKLMQLTNVSRAKAEDALSEmksqyskvlNELTQLKQLVDAQKENsvsitehlqvITTLR 733
Cdd:COG4913 255 EPIRELAeryaaarERLAELEYLRAALRLWFAQRRLELLE---------AELEELRAELARLEAE----------LERLE 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 734 TAAKEMEEKISNLKEHLASKEVE-VAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKEsvkekekvhse 812
Cdd:COG4913 316 ARLDALREELDELEAQIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAA----------- 384
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 966946461 813 vaqirsEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKR 860
Cdd:COG4913 385 ------LRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA 426
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
94-242 |
6.86e-04 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 43.12 E-value: 6.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 94 IRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPL--LLAVQNGHSEICHFLLDHGADVN 171
Cdd:PHA02946 55 VEELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLyyLSGTDDEVIERINLLVQYGAKIN 134
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966946461 172 SRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDSLGHNALHYSKLSEN------AGIQSLLLSKISQDADLKTP 242
Cdd:PHA02946 135 NSVDEEGCGPLLACTDPSERVFKKIMSIGFEARIVDKFGKNHIHRHLMSDNpkastiSWMMKLGISPSKPDHDGNTP 211
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
589-911 |
6.87e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.81 E-value: 6.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 589 LFEKYQEAQEEIMKLKDTLKS--QMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELED-YRKRKSLEDITA 665
Cdd:pfam02463 178 LIEETENLAELIIDLEELKLQelKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQElLRDEQEEIESSK 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 666 EYIHKAEHEKLMQLTNVSRAKAEDALSEMK-SQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKIS 744
Cdd:pfam02463 258 QEIEKEEEKLAQVLKENKEEEKEKKLQEEElKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEI 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 745 N-----LKEHLASKEVEVAKLEKQLLEEKAAmtdamvprssyEKLQSSLESEVSVLASKLKESVKEKEKVH---SEVAQI 816
Cdd:pfam02463 338 EelekeLKELEIKREAEEEEEEELEKLQEKL-----------EQLEEELLAKKKLESERLSSAAKLKEEELelkSEEEKE 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 817 RSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKkinEMSKEVTKLKEALNSLSQL 896
Cdd:pfam02463 407 AQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDE---LELKKSEDLLKETQLVKLQ 483
|
330
....*....|....*
gi 966946461 897 SYSTSSSKRQSQQLE 911
Cdd:pfam02463 484 EQLELLLSRQKLEER 498
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
147-171 |
6.92e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 38.01 E-value: 6.92e-04
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
418-890 |
7.18e-04 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 43.67 E-value: 7.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 418 DSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELvclNNTEISENSSDLSQKLKETQSKYEEA-----MKEVL 492
Cdd:PTZ00440 592 EIDNIIQQIEELINEALFNKEKFINEKNDLQEKVKYILNKF---YKGDLQELLDELSHFLDDHKYLYHEAkskedLQTLL 668
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 493 --SVQKQMKLGLVSPESMDNY--------SHLHELR--VTEEEINVLKQDLQNALEESernkekvreleeklveREKGTV 560
Cdd:PTZ00440 669 ntSKNEYEKLEFMKSDNIDNIiknlkkelQNLLSLKenIIKKQLNNIEQDISNSLNQY----------------TIKYND 732
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 561 IKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTlksqmtqeaSDEAEDMKEAMNRMIDELNKQVSEL 640
Cdd:PTZ00440 733 LKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDLPDGKNT---------YEEFLQYKDTILNKENKISNDINIL 803
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 641 SQLYKEAQAELEDYR-KRKSLEDITAEyiHKAEHEKLMQ-----LTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDA 714
Cdd:PTZ00440 804 KENKKNNQDLLNSYNiLIQKLEAHTEK--NDEELKQLLQkfpteDENLNLKELEKEFNENNQIVDNIIKDIENMNKNINI 881
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 715 QKENSVSITE---HLQVITTLRTAAKEMEEKISNLKEHLASKEV----EVAKLEKQLLEEKAAM-------------TDA 774
Cdd:PTZ00440 882 IKTLNIAINRsnsNKQLVEHLLNNKIDLKNKLEQHMKIINTDNIiqknEKLNLLNNLNKEKEKIekqlsdtkinnlkMQI 961
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 775 MVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSEV--------SQVKREKENIQTL----LKSKEQEVN 842
Cdd:PTZ00440 962 EKTLEYYDKSKENINGNDGTHLEKLDKEKDEWEHFKSEIDKLNVNYnilnkkidDLIKKQHDDIIELidklIKEKGKEIE 1041
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 966946461 843 ELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEAL 890
Cdd:PTZ00440 1042 EKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEAL 1089
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
409-789 |
7.84e-04 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 43.30 E-value: 7.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 409 IHALGKSTTDSDVRIQQLQEILQDLQKRL--------ESSEAERKQLQvELQSRRAELVCLNNT-----------EISEN 469
Cdd:pfam06160 109 LDELLESEEKNREEVEELKDKYRELRKTLlanrfsygPAIDELEKQLA-EIEEEFSQFEELTESgdylearevleKLEEE 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 470 SSDLSQK-------LKETQSKYEEAMKEVLSVQKQMKlglvspesMDNYsHLHELRVtEEEINVLKQDLQNALEESERNK 542
Cdd:pfam06160 188 TDALEELmedipplYEELKTELPDQLEELKEGYREME--------EEGY-ALEHLNV-DKEIQQLEEQLEENLALLENLE 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 543 -EKVRELEEKLVERekgtvIKPPVEEYEEMKSSYCSVIENMNKEKAFLF---EKYQEAQEEIMKLKDT-LKSQMTQEASD 617
Cdd:pfam06160 258 lDEAEEALEEIEER-----IDQLYDLLEKEVDAKKYVEKNLPEIEDYLEhaeEQNKELKEELERVQQSyTLNENELERVR 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 618 EAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRksLEDITAEyiHKAEHEKLMQLTNVSRaKAEDALSEMKsq 697
Cdd:pfam06160 333 GLEKQLEELEKRYDEIVERLEEKEVAYSELQEELEEILEQ--LEEIEEE--QEEFKESLQSLRKDEL-EAREKLDEFK-- 405
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 698 yskvlNELTQLKQLVdaQKEN----SVSITEHL-QVITTLRTAAKEMEEKISNLKE-----HLASKEVEVAKLEKQLLEE 767
Cdd:pfam06160 406 -----LELREIKRLV--EKSNlpglPESYLDYFfDVSDEIEDLADELNEVPLNMDEvnrllDEAQDDVDTLYEKTEELID 478
|
410 420
....*....|....*....|....*..
gi 966946461 768 KAAMTDAMVP-----RSSYEKLQSSLE 789
Cdd:pfam06160 479 NATLAEQLIQyanryRSSNPEVAEALT 505
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
475-864 |
7.97e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 43.63 E-value: 7.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 475 QKLKETQSKYEEAMKEVLSVQKQmklglVSPESMDNYSHLH---ELRVTEEEINVL----KQDLQNALEESERNKEKVRE 547
Cdd:pfam01576 15 QKVKERQQKAESELKELEKKHQQ-----LCEEKNALQEQLQaetELCAEAEEMRARlaarKQELEEILHELESRLEEEEE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 548 LEEKLVEREKGtvIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTlKSQMTQEASDEAEDMKEAMN 627
Cdd:pfam01576 90 RSQQLQNEKKK--MQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQ-NSKLSKERKLLEERISEFTS 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 628 RMIDELN--KQVSELSQLYKEAQAELEDYRKRKsleditaeyihkaehEKLMQLTNVSRAKAEDALSEMKSQYSKVLNEL 705
Cdd:pfam01576 167 NLAEEEEkaKSLSKLKNKHEAMISDLEERLKKE---------------EKGRQELEKAKRKLEGESTDLQEQIAELQAQI 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 706 TQLKQLVDAQKENSVSITEHLQVITTLRTAA----KEMEEKISNLKEHLASKEVEVAKLEKQ---LLEE----KAAMTDA 774
Cdd:pfam01576 232 AELRAQLAKKEEELQAALARLEEETAQKNNAlkkiRELEAQISELQEDLESERAARNKAEKQrrdLGEElealKTELEDT 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 775 MVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQ--------IRSEVSQVKREKENIQTLLKSKEQEVNEL-- 844
Cdd:pfam01576 312 LDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQkhtqaleeLTEQLEQAKRNKANLEKAKQALESENAELqa 391
|
410 420
....*....|....*....|.
gi 966946461 845 -LQKFQQAQEELAEMKRYSES 864
Cdd:pfam01576 392 eLRTLQQAKQDSEHKRKKLEG 412
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
566-891 |
9.45e-04 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 42.90 E-value: 9.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 566 EEYEEMKSSYCSVIENmnkekafLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYK 645
Cdd:PRK04778 64 EKFEEWRQKWDEIVTN-------SLPDIEEQLFEAEELNDKFRFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEE 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 646 EAQAE----LEDYRK-RKSLED------ITAEYIHK------AEHEKLMQLTN----------VSRAKAE-DALSEMKSQ 697
Cdd:PRK04778 137 KNREEveqlKDLYRElRKSLLAnrfsfgPALDELEKqlenleEEFSQFVELTEsgdyveareiLDQLEEElAALEQIMEE 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 698 YSKVLNELT-----QLKQLVDAQKENSVS--ITEHLQVITTLrtaaKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKaa 770
Cdd:PRK04778 217 IPELLKELQtelpdQLQELKAGYRELVEEgyHLDHLDIEKEI----QDLKEQIDENLALLEELDLDEAEEKNEEIQER-- 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 771 mTDAMvprssYEKLQSSLESEVSVLasKLKESVKEK-EKVHSEVAQIRSEVSQVK-------REKENIQTLLKskeqEVN 842
Cdd:PRK04778 291 -IDQL-----YDILEREVKARKYVE--KNSDTLPDFlEHAKEQNKELKEEIDRVKqsytlneSELESVRQLEK----QLE 358
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 966946461 843 ELLQKFQQAQEELAE-MKRYSESSSKLEEDkDKKINEMSKEVTKLKEALN 891
Cdd:PRK04778 359 SLEKQYDEITERIAEqEIAYSELQEELEEI-LKQLEEIEKEQEKLSEMLQ 407
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
529-829 |
1.17e-03 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 42.82 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 529 QDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK 608
Cdd:pfam09731 124 QEKEKALEEVLKEAISKAESATAVAKEAKDDAIQAVKAHTDSLKEASDTAEISREKATDSALQKAEALAEKLKEVINLAK 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 609 SQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAqAELEDYRKRKSLEDItaeyIHKAEHEKLMqlTNVSRAKAE 688
Cdd:pfam09731 204 QSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKAQSLA-KLVDQYKELVASERI----VFQQELVSIF--PDIIPVLKE 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 689 DALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVIttLRTAAKEMEEKISNLKEHLaskEVEVAKLEKQLLEEK 768
Cdd:pfam09731 277 DNLLSNDDLNSLIAHAHREIDQLSKKLAELKKREEKHIERA--LEKQKEELDKLAEELSARL---EEVRAADEAQLRLEF 351
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966946461 769 AAMTDAMvpRSSYE-KLQSSLESEVSVLASKLKESVKEKEkVHSEVAQIRSEVSQVKREKEN 829
Cdd:pfam09731 352 EREREEI--RESYEeKLRTELERQAEAHEEHLKDVLVEQE-IELQREFLQDIKEKVEEERAG 410
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
409-653 |
1.24e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 42.11 E-value: 1.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 409 IHALGKSTTDSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELV------CLNNTEISENS-----SDLSQKL 477
Cdd:pfam15905 82 IRALVQERGEQDKRLQALEEELEKVEAKLNAAVREKTSLSASVASLEKQLLeltrvnELLKAKFSEDGtqkkmSSLSMEL 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 478 KETQSKYEEAMKEVLSVQKQMKLGLvspesmdnyshlhelrvteeeinvlkQDLQNALEESernKEKVRELEEKLVEREK 557
Cdd:pfam15905 162 MKLRNKLEAKMKEVMAKQEGMEGKL--------------------------QVTQKNLEHS---KGKVAQLEEKLVSTEK 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 558 GTVikppVEEYEEMKssycsvIENMNKEKAFLFEKYQEAQEEIMKLKDTLKsqmtqEASDEAEDMKEAMNRMIDELNKQV 637
Cdd:pfam15905 213 EKI----EEKSETEK------LLEYITELSCVSEQVEKYKLDIAQLEELLK-----EKNDEIESLKQSLEEKEQELSKQI 277
|
250
....*....|....*.
gi 966946461 638 SELSQLYKEAQAELED 653
Cdd:pfam15905 278 KDLNEKCKLLESEKEE 293
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
706-885 |
1.46e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 42.31 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 706 TQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDA----------- 774
Cdd:PHA02562 199 TYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIkskieqfqkvi 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 775 ------------MVPRSSYEKLQSSLESEVSVLA---SKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQ 839
Cdd:PHA02562 279 kmyekggvcptcTQQISEGPDRITKIKDKLKELQhslEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVD 358
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 966946461 840 EVNELLQKFQQAQeelAEMKRYSESSSKLEEDKDKKINEMSKEVTK 885
Cdd:PHA02562 359 KAKKVKAAIEELQ---AEFVDNAEELAKLQDELDKIVKTKSELVKE 401
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
685-915 |
1.59e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.06 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 685 AKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQV----ITTLRTAAKEMEEKISNLKEHLASKEVEVAKL 760
Cdd:COG4942 16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAlerrIAALARRIRALEQELAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 761 EKQLLEEKAAMTDAMvpRSSYeklQSSLESEVSVL--ASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKE 838
Cdd:COG4942 96 RAELEAQKEELAELL--RALY---RLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966946461 839 QEVNELLQKFQQAQEELAEMkrysessSKLEEDKDKKINEMSKEvtklkealnslsqlsystssSKRQSQQLEALQQ 915
Cdd:COG4942 171 AERAELEALLAELEEERAAL-------EALKAERQKLLARLEKE--------------------LAELAAELAELQQ 220
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
630-806 |
1.61e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 630 IDELNKQVSELSQLYKEAQAELEDYRKRksLEDITAEyihKAEHEKLMQLTNVSRAKAEDALSEMKSQyskvlneltqlK 709
Cdd:COG1579 26 LKELPAELAELEDELAALEARLEAAKTE--LEDLEKE---IKRLELEIEEVEARIKKYEEQLGNVRNN-----------K 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 710 QLVDAQKEnsvsITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMvprSSYEKLQSSLE 789
Cdd:COG1579 90 EYEALQKE----IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEEL---AELEAELEELE 162
|
170
....*....|....*..
gi 966946461 790 SEVSVLASKLKESVKEK 806
Cdd:COG1579 163 AEREELAAKIPPELLAL 179
|
|
| Macoilin |
pfam09726 |
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ... |
632-866 |
1.64e-03 |
|
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.
Pssm-ID: 462859 [Multi-domain] Cd Length: 670 Bit Score: 42.15 E-value: 1.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 632 ELNKQVSELSQLYKEAQAELEDYRKRKsleDITAEYIHKAEHEKLMQLTNVS----RAKAEdalSEMKSQYSKVLNELTQ 707
Cdd:pfam09726 420 ELRSQISSLTSLERSLKSELGQLRQEN---DLLQTKLHNAVSAKQKDKQTVQqlekRLKAE---QEARASAEKQLAEEKK 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 708 LKQLVDAQKENSVS--ITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEekaamtdamvpRSSYEKLQ 785
Cdd:pfam09726 494 RKKEEEATAARAVAlaAASRGECTESLKQRKRELESEIKKLTHDIKLKEEQIRELEIKVQE-----------LRKYKESE 562
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 786 SSLESEVSVLaSKLKESVKEKEKVHSEVAQIR----SEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 861
Cdd:pfam09726 563 KDTEVLMSAL-SAMQDKNQHLENSLSAETRIKldlfSALGDAKRQLEIAQGQIYQKDQEIKDLKQKIAEVMAVMPSTSRI 641
|
....*
gi 966946461 862 SESSS 866
Cdd:pfam09726 642 TPVTP 646
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
468-876 |
1.64e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 42.40 E-value: 1.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 468 ENSSDLSQKLKETQSKyeeAMKEVLSVQKQMKLGLvSPESMDNYSHLHELRVTEEEINVLKQDLQNALEESERNKEKVRE 547
Cdd:pfam05483 105 ENKLQENRKIIEAQRK---AIQELQFENEKVSLKL-EEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREE 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 548 LEEKLVEREKGtvIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMT------QEASDEAED 621
Cdd:pfam05483 181 TRQVYMDLNNN--IEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSllliqiTEKENKMKD 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 622 MKEAMNRMIDELNkQVSELSQLYKEAQAELEDYRKR--KSLEDITAEyihkaehekLMQLTNVSRAKAEDALSEMKSQYS 699
Cdd:pfam05483 259 LTFLLEESRDKAN-QLEEKTKLQDENLKELIEKKDHltKELEDIKMS---------LQRSMSTQKALEEDLQIATKTICQ 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 700 KVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEekaaMTdamvprs 779
Cdd:pfam05483 329 LTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEE----MT------- 397
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 780 syeKLQSSLESEVsvlaSKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNEL-LQKFQQAQEELAEM 858
Cdd:pfam05483 398 ---KFKNNKEVEL----EELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLeIQLTAIKTSEEHYL 470
|
410
....*....|....*...
gi 966946461 859 KRYSESSSKLEEDKDKKI 876
Cdd:pfam05483 471 KEVEDLKTELEKEKLKNI 488
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
702-857 |
1.65e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.19 E-value: 1.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 702 LNELTQLKQLVDAQKENSVSitEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQ----------LLEEKAAM 771
Cdd:pfam07888 43 RAELLQAQEAANRQREKEKE--RYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKykelsasseeLSEEKDAL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 772 TDAmvpRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQA 851
Cdd:pfam07888 121 LAQ---RAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQEL 197
|
....*.
gi 966946461 852 QEELAE 857
Cdd:pfam07888 198 RNSLAQ 203
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
152-222 |
1.66e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 42.36 E-value: 1.66e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 966946461 152 VQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADLNLVDSLGHNALHYSKLSEN 222
Cdd:PHA02876 153 IQQDELLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKN 223
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
506-757 |
2.08e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 506 ESMDNYSHLHE-LRVTEEEINVLKQ--DLQNALEESERNKEKVRELEEKLverekgtvikpPVEEYEEMKSSYCSVIENM 582
Cdd:COG4913 232 EHFDDLERAHEaLEDAREQIELLEPirELAERYAAARERLAELEYLRAAL-----------RLWFAQRRLELLEAELEEL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 583 NKEKAFLFEKYQEAQEEIMKLK---DTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQA-ELEDYRKRK 658
Cdd:COG4913 301 RAELARLEAELERLEARLDALReelDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAAlGLPLPASAE 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 659 SLEDITAEYI-HKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQlvdaqkeNSVSITEHLQvitTLRTAak 737
Cdd:COG4913 381 EFAALRAEAAaLLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER-------RKSNIPARLL---ALRDA-- 448
|
250 260
....*....|....*....|
gi 966946461 738 emeekisnLKEHLASKEVEV 757
Cdd:COG4913 449 --------LAEALGLDEAEL 460
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
514-883 |
2.23e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.96 E-value: 2.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 514 LHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKgtvikppveEYEEMKSSYCSViENMNKEKAFLFEKY 593
Cdd:TIGR00606 579 LHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLS---------SYEDKLFDVCGS-QDEESDLERLKEEI 648
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 594 QEAQEEIMKL--KDTLKSQMTQEASDEAEDMKEAMNRMID---ELNKQVSELSQLYKEAQAELEDYRKR-KSLEDITAEY 667
Cdd:TIGR00606 649 EKSSKQRAMLagATAVYSQFITQLTDENQSCCPVCQRVFQteaELQEFISDLQSKLRLAPDKLKSTESElKKKEKRRDEM 728
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 668 IHKAEheklMQLTNVSRAKAEdaLSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLK 747
Cdd:TIGR00606 729 LGLAP----GRQSIIDLKEKE--IPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELK 802
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 748 EHLASKEVEVAKLE-----------KQLLEEKAAMTDAMVPRSSY-EKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQ 815
Cdd:TIGR00606 803 DVERKIAQQAAKLQgsdldrtvqqvNQEKQEKQHELDTVVSKIELnRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQR 882
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966946461 816 IRSEVSQVKREKENIQTLLKSKEQEVNEL------LQKFQQAQEELAEMKrysESSSKLEEDKdkkINEMSKEV 883
Cdd:TIGR00606 883 RQQFEEQLVELSTEVQSLIREIKDAKEQDspletfLEKDQQEKEELISSK---ETSNKKAQDK---VNDIKEKV 950
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
516-657 |
2.40e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 2.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 516 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREK--GTVIKPpvEEYEEMKSSycsvIENMNKEKAFLFEKY 593
Cdd:COG1579 39 ELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEqlGNVRNN--KEYEALQKE----IESLKRRISDLEDEI 112
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966946461 594 QEAQEEIMKLKDTLKsqmtqEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKR 657
Cdd:COG1579 113 LELMERIEELEEELA-----ELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
420-646 |
2.42e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.54 E-value: 2.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 420 DVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCL---NNTEISENSSDLSqKLKETQSKYEEAMKEVLSVQK 496
Cdd:PHA02562 187 DMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEaktIKAEIEELTDELL-NLVMDIEDPSAALNKLNTAAA 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 497 QMKlglvspESMDNYSHLHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLverekgTVIKPPVEEYEEMKSSYC 576
Cdd:PHA02562 266 KIK------SKIEQFQKVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSL------EKLDTAIDELEEIMDEFN 333
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 577 SVIENMNKEKAFLFEKYQEAQEEIMKLKDtLKSQMtQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKE 646
Cdd:PHA02562 334 EQSKKLLELKNKISTNKQSLITLVDKAKK-VKAAI-EELQAEFVDNAEELAKLQDELDKIVKTKSELVKE 401
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
619-854 |
2.63e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.35 E-value: 2.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 619 AEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEdyRKRKSLEDITAEyihKAEHEKLMQLTNVSRAKAEDALSEMKSQY 698
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQAELDALQAELE--ELNEEYNELQAE---LEALQAEIDKLQAEIAEAEAEIEERREEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 699 SKVLNEL-------TQLKQLVDAQkensvSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAM 771
Cdd:COG3883 89 GERARALyrsggsvSYLDVLLGSE-----SFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 772 TDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQA 851
Cdd:COG3883 164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 243
|
...
gi 966946461 852 QEE 854
Cdd:COG3883 244 ASA 246
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
46-73 |
2.87e-03 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.03 E-value: 2.87e-03
10 20
....*....|....*....|....*...
gi 966946461 46 KHCFHLAAAKGHVECLRVMVTHGVDVTA 73
Cdd:smart00248 3 RTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
583-909 |
2.94e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 41.48 E-value: 2.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 583 NKEKAFLFEKYQEAQEEIMKLKDTLKsqmtQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLED 662
Cdd:COG5185 241 PESELEDLAQTSDKLEKLVEQNTDLR----LEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEE 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 663 ITAEYIHKAEHEKLMqltnvsrAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEK 742
Cdd:COG5185 317 QLAAAEAEQELEESK-------RETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKSSEELDSFKDTIEST 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 743 ISNLKEHLASkevevAKLEKQLLEEKAAMTDAMVPRSSyEKLQSSLESevsvLASKLKESVKEKEKVHSEVAQIRSEVSQ 822
Cdd:COG5185 390 KESLDEIPQN-----QRGYAQEILATLEDTLKAADRQI-EELQRQIEQ----ATSSNEEVSKLLNELISELNKVMREADE 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 823 VKREK--ENIQTLLKSKEQEVNELLQKFQQAQEELAEMKrysESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 900
Cdd:COG5185 460 ESQSRleEAYDEINRSVRSKKEDLNEELTQIESRVSTLK---ATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYA 536
|
....*....
gi 966946461 901 SSSKRQSQQ 909
Cdd:COG5185 537 HILALENLI 545
|
|
| MPS2 |
pfam17060 |
Monopolar spindle protein 2; Is a fungal transmembrane protein which is part of the component ... |
542-754 |
3.02e-03 |
|
Monopolar spindle protein 2; Is a fungal transmembrane protein which is part of the component of the spindle pole body (SPB) required for the insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication. It seems that Mps2-Spc24 interaction may contribute to the localization of Spc24 and other kinetochore components to the inner plaque of the SPB.
Pssm-ID: 407228 [Multi-domain] Cd Length: 340 Bit Score: 41.11 E-value: 3.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 542 KEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIEnmnkekaflfekyqeaqeeimkLKDTLKSQMTQEASDEAED 621
Cdd:pfam17060 67 KESFSEMFNGLVGNNFKTVINKIFEDCDGIPASFISALE----------------------LKEDVKSSPRSEADSLGTP 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 622 MKEAMNRMI--DELNKQVSELSQLYKEAQAELEDYRKRKSLEDitaEYIHKAEHEkLMQLTNvsrakaedALSEMKSQYS 699
Cdd:pfam17060 125 IKVDLLRNLkpQESPETPRRINRKYKSLELRVESMKDELEFKD---ETIMEKDRE-LTELTS--------TISKLKDKYD 192
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 966946461 700 KVLNELTQLKQLVDAQKENSV-SITEHLQVITTLRTAAKEMEEKISNLKEHLASKE 754
Cdd:pfam17060 193 FLSREFEFYKQHHEHGGNNSIkTATKHEFIISELKRKLQEQNRLIRILQEQIQFDP 248
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
745-891 |
3.26e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 40.77 E-value: 3.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 745 NLKEHLAsKEVEVAKLEKQLLEEKAAMTDAMVPRSSyeKLQSSLESEVSVLasklKESVKEKEKVH-SEVAQIRSEVSQV 823
Cdd:smart00787 144 GLKEGLD-ENLEGLKEDYKLLMKELELLNSIKPKLR--DRKDALEEELRQL----KQLEDELEDCDpTELDRAKEKLKKL 216
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966946461 824 KREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMK-RYSESSSKLEEDKDKKInemsKEVTKLKEALN 891
Cdd:smart00787 217 LQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNtEIAEAEKKLEQCRGFTF----KEIEKLKEQLK 281
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
517-860 |
3.55e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.03 E-value: 3.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 517 LRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREkgTVIKPPVEEYEEMKSSYCSVI---ENMNKEKAFLFEKY 593
Cdd:pfam07888 47 LQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELK--EELRQSREKHEELEEKYKELSassEELSEEKDALLAQR 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 594 QEAQEEIMKLKDTLK--SQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL-YKEAQAELEDYRKRKSLEditaeyihk 670
Cdd:pfam07888 125 AAHEARIRELEEDIKtlTQRVLERETELERMKERAKKAGAQRKEEEAERKQLqAKLQQTEEELRSLSKEFQ--------- 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 671 aeheklmqltnvsraKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHL 750
Cdd:pfam07888 196 ---------------ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEEL 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 751 AS--------------KEVEVAKLEKQLLEEKAAMTDAmvpRSSY----EKLQSSLESEVSVLASKLKESVKEKEKVHSE 812
Cdd:pfam07888 261 SSmaaqrdrtqaelhqARLQAAQLTLQLADASLALREG---RARWaqerETLQQSAEADKDRIEKLSAELQRLEERLQEE 337
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 966946461 813 VAQIRSEVSQVKREKENIQTLLKSKEQEVNEL---LQKFQQAQEELAEMKR 860
Cdd:pfam07888 338 RMEREKLEVELGREKDCNRVQLSESRRELQELkasLRVAQKEKEQLQAEKQ 388
|
|
| PHA02791 |
PHA02791 |
ankyrin-like protein; Provisional |
94-239 |
4.25e-03 |
|
ankyrin-like protein; Provisional
Pssm-ID: 165154 [Multi-domain] Cd Length: 284 Bit Score: 40.41 E-value: 4.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 94 IRKLLQSKcPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLkdLDGNIPLLLAVQNGHSEICHFLLDHGADVNSR 173
Cdd:PHA02791 14 LKSFLSSK-DAFKADVHGHSALYYAIADNNVRLVCTLLNAGALKNL--LENEFPLHQAATLEDTKIVKILLFSGMDDSQF 90
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966946461 174 NKSGRTALMLACEIGSSNVVEALIKKGADLNLVDSLG-HNALHYSKLSENAGIQSLLLSKISQDADL 239
Cdd:PHA02791 91 DDKGNTALYYAVDSGNMQTVKLFVKKNWRLMFYGKTGwKTSFYHAVMLNDVSIVSYFLSEIPSTFDL 157
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
424-912 |
4.29e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.11 E-value: 4.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 424 QQLQEILQDLQKRLESSEAERKQLQVELQsrraelvclnNTEISENSSDLSQKLKETQSKYEEAMKEVLSvqkqmklglv 503
Cdd:TIGR00618 208 LCTPCMPDTYHERKQVLEKELKHLREALQ----------QTQQSHAYLTQKREAQEEQLKKQQLLKQLRA---------- 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 504 spesmdnyshlhelrvTEEEINVLKQDLQNALEESERNKEKvreleEKLVEREKGtvikppVEEYEEMKSSYCSVIENMN 583
Cdd:TIGR00618 268 ----------------RIEELRAQEAVLEETQERINRARKA-----APLAAHIKA------VTQIEQQAQRIHTELQSKM 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 584 KEKAFLFEKYQEAQEEIMKLKDTLKS-QMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSL-- 660
Cdd:TIGR00618 321 RSRAKLLMKRAAHVKQQSSIEEQRRLlQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLck 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 661 -------EDITAEYIHKAEHEKLMQLTnVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLR 733
Cdd:TIGR00618 401 eldilqrEQATIDTRTSAFRDLQGQLA-HAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKE 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 734 TAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQsSLESEVSVLAsklkesvKEKEKVHSEV 813
Cdd:TIGR00618 480 QIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQ-RGEQTYAQLE-------TSEEDVYHQL 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 814 AQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEedkDKKINEMSKEVTKLKEALNSL 893
Cdd:TIGR00618 552 TSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAE---DMLACEQHALLRKLQPEQDLQ 628
|
490
....*....|....*....
gi 966946461 894 SQLSYSTSSSKRQSQQLEA 912
Cdd:TIGR00618 629 DVRLHLQQCSQELALKLTA 647
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
177-230 |
4.67e-03 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 36.10 E-value: 4.67e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 966946461 177 GRTALMLACEIGSSNVVEALIKKGADLNLVDSLGHNALHYSKLSENAGIQSLLL 230
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
121-224 |
4.69e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 40.82 E-value: 4.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 121 QGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKG 200
Cdd:PHA02876 155 QDELLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNR 234
|
90 100
....*....|....*....|....*....
gi 966946461 201 A-----DLNLVDSLGHNALHYSKLSENAG 224
Cdd:PHA02876 235 SninknDLSLLKAIRNEDLETSLLLYDAG 263
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
424-867 |
4.70e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 40.80 E-value: 4.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 424 QQLQEILQDLQKRLESSEAERKQLQV----------ELQSRRAELVClnNTEISENSSDLSQKLKETQSKYEEAMKEVLS 493
Cdd:TIGR00606 189 ETLRQVRQTQGQKVQEHQMELKYLKQykekaceirdQITSKEAQLES--SREIVKSYENELDPLKNRLKEIEHNLSKIMK 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 494 VQKQMKLGLVSPESMDN-YSHLHELRV-----TEEEINVLKQDLQNALEESERNKEKV-RELEEKLVEREKGTVIKPPVE 566
Cdd:TIGR00606 267 LDNEIKALKSRKKQMEKdNSELELKMEkvfqgTDEQLNDLYHNHQRTVREKERELVDCqRELEKLNKERRLLNQEKTELL 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 567 EYEEMKSSYCSVIENMNKEKAFLFEKYQeAQEEIMKLKDTLKSQMtqEASDEAEDMKEAMNRMIDELNKQVSELSQLYKE 646
Cdd:TIGR00606 347 VEQGRLQLQADRHQEHIRARDSLIQSLA-TRLELDGFERGPFSER--QIKNFHTLVIERQEDEAKTAAQLCADLQSKERL 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 647 AQAELEDYRKRKSLEDITAEYIHKAEHEKLMQLTNVSR-----AKAEDALSEMKSQYSKVLNELTQLKQ--LVDAQKENS 719
Cdd:TIGR00606 424 KQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKelqqlEGSSDRILELDQELRKAERELSKAEKnsLTETLKKEV 503
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 720 VSI-TEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEK--QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLA 796
Cdd:TIGR00606 504 KSLqNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKdeQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKS 583
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 966946461 797 SKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKfQQAQEELAEMKRYSESSSK 867
Cdd:TIGR00606 584 KEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEIEKSSK 653
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
419-828 |
4.92e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 41.19 E-value: 4.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 419 SDVRIQQLQEI--------LQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKE 490
Cdd:TIGR01612 1301 SDIREKSLKIIedfseesdINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNILKLNKIKKIIDEVKEYTKEIEENNKN 1380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 491 VLSvqkqmklglvspesmdnyshlhELRVTEEEINVLKQDLqnALEESERNKEKVreLEEKLVER--EKGTVIKPPVEEY 568
Cdd:TIGR01612 1381 IKD----------------------ELDKSEKLIKKIKDDI--NLEECKSKIEST--LDDKDIDEciKKIKELKNHILSE 1434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 569 EEMKSSYCSVIENMNKEKAFLFEKYQEAQEeimKLKDTLKSQMTQEASDEAEDMKEaMNRMIDELNKQVSELSQLYKEAQ 648
Cdd:TIGR01612 1435 ESNIDTYFKNADENNENVLLLFKNIEMADN---KSQHILKIKKDNATNDHDFNINE-LKEHIDKSKGCKDEADKNAKAIE 1510
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 649 AELEDYRKRKslEDITaEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHL-- 726
Cdd:TIGR01612 1511 KNKELFEQYK--KDVT-ELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAak 1587
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 727 -----QVITTLRTAAKEMEEK---ISNLKEHLASKEVEVAKLEKQL--LEEKAAMTDAMVPRSSYEKLQSSLESeVSVLA 796
Cdd:TIGR01612 1588 ndksnKAAIDIQLSLENFENKflkISDIKKKINDCLKETESIEKKIssFSIDSQDTELKENGDNLNSLQEFLES-LKDQK 1666
|
410 420 430
....*....|....*....|....*....|..
gi 966946461 797 SKLKESVKEKEKVHSEVAQIRSEVSQVKREKE 828
Cdd:TIGR01612 1667 KNIEDKKKELDELDSEIEKIEIDVDQHKKNYE 1698
|
|
| Borrelia_P83 |
pfam05262 |
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins. |
709-889 |
5.77e-03 |
|
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
Pssm-ID: 114011 [Multi-domain] Cd Length: 489 Bit Score: 40.37 E-value: 5.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 709 KQLVDAQKENSVSITEHLQVITTLRT-AAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMvpRSSYEKLQSS 787
Cdd:pfam05262 180 KKVVEALREDNEKGVNFRRDMTDLKErESQEDAKRAQQLKEELDKKQIDADKAQQKADFAQDNADKQR--DEVRQKQQEA 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 788 --LESEVSVLASKLKESVKEKEKVHSEVAQIRSevsqvkreKENIQTLLKSKEQEVNELLQKfQQAQEELAEMKRySESS 865
Cdd:pfam05262 258 knLPKPADTSSPKEDKQVAENQKREIEKAQIEI--------KKNDEEALKAKDHKAFDLKQE-SKASEKEAEDKE-LEAQ 327
|
170 180
....*....|....*....|....*..
gi 966946461 866 SKLEE---DKDKKINEMSKEVTKLKEA 889
Cdd:pfam05262 328 KKREPvaeDLQKTKPQVEAQPTSLNED 354
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
599-824 |
6.21e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 40.71 E-value: 6.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 599 EIMKLKDTLKSQMTQEASDEAEDMKEAMN------RMIDELNKQVS----------ELSQLYKEAQAELEDYRKRK-SLE 661
Cdd:COG3096 882 QANLLADETLADRLEELREELDAAQEAQAfiqqhgKALAQLEPLVAvlqsdpeqfeQLQADYLQAKEQQRRLKQQIfALS 961
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 662 DITAEYIHKAEHEKLMQLTNVS----------------RAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEnsvsiteh 725
Cdd:COG3096 962 EVVQRRPHFSYEDAVGLLGENSdlneklrarleqaeeaRREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQ-------- 1033
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 726 lqvitTLRTAAKEMEEkisnLKEHLASKEVEVAKLEKQLLEEKAAMTDAMvpRSSYEKLQSSLESEVSVLASKLKesvke 805
Cdd:COG3096 1034 -----TLQELEQELEE----LGVQADAEAEERARIRRDELHEELSQNRSR--RSQLEKQLTRCEAEMDSLQKRLR----- 1097
|
250
....*....|....*....
gi 966946461 806 keKVHSEVAQIRSEVSQVK 824
Cdd:COG3096 1098 --KAERDYKQEREQVVQAK 1114
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
50-112 |
6.68e-03 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 40.27 E-value: 6.68e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966946461 50 HLAAAKGHVECLRVMVTHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGK 112
Cdd:PTZ00322 120 HIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRHSQCHFELGANAK 182
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
409-676 |
7.03e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 40.39 E-value: 7.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 409 IHALGKSTTDSDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVcLNNTEISEnssdlsqkLKETQSKYEEAM 488
Cdd:TIGR04523 386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETII-KNNSEIKD--------LTNQDSVKELII 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 489 KEVLSVQKQMKlglvspesmdnyshlHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKgtvikpPVEEY 568
Cdd:TIGR04523 457 KNLDNTRESLE---------------TQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEE------KVKDL 515
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 569 EEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQ 648
Cdd:TIGR04523 516 TKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKE 595
|
250 260 270
....*....|....*....|....*....|....
gi 966946461 649 AELEDYRKRKSLEDITAEYIH------KAEHEKL 676
Cdd:TIGR04523 596 KEKKDLIKEIEEKEKKISSLEkelekaKKENEKL 629
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
536-718 |
8.02e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 40.00 E-value: 8.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 536 EESERNKEKVRELEEKLVE-REKGTVIKPPveeyEEMKSSYcSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQE 614
Cdd:COG3206 182 EQLPELRKELEEAEAALEEfRQKNGLVDLS----EEAKLLL-QQLSELESQLAEARAELAEAEARLAALRAQLGSGPDAL 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 615 ASDEAEDMKEAMNRMIDELNKQVSELSQLY-------KEAQAELEDYRKRksLEDITAEYIHKAEHEKLMQLTNVSRAKA 687
Cdd:COG3206 257 PELLQSPVIQQLRAQLAELEAELAELSARYtpnhpdvIALRAQIAALRAQ--LQQEAQRILASLEAELEALQAREASLQA 334
|
170 180 190
....*....|....*....|....*....|..
gi 966946461 688 E-DALSEMKSQYSKVLNELTQLKQLVDAQKEN 718
Cdd:COG3206 335 QlAQLEARLAELPELEAELRRLEREVEVAREL 366
|
|
| PHA02989 |
PHA02989 |
ankyrin repeat protein; Provisional |
125-203 |
8.10e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222954 [Multi-domain] Cd Length: 494 Bit Score: 39.72 E-value: 8.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 125 QAVQILCEHKSPINLKDLDGNIPLLLAVQNGH---SEICHFLLDHGADVNS-RNKSGRTALMLACE--IGSSNVVEALIK 198
Cdd:PHA02989 89 KIVKLLLKFGADINLKTFNGVSPIVCFIYNSNinnCDMLRFLLSKGINVNDvKNSRGYNLLHMYLEsfSVKKDVIKILLS 168
|
....*
gi 966946461 199 KGADL 203
Cdd:PHA02989 169 FGVNL 173
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
623-891 |
8.19e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 40.33 E-value: 8.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 623 KEAMNRMIDELNKQVSELSQLYKEAQAELEDY-RKRKSLEDITAEYIHKA---EHEKLMQLTNVSRAKAEDALSEMKSQY 698
Cdd:PRK04863 781 RAAREKRIEQLRAEREELAERYATLSFDVQKLqRLHQAFSRFIGSHLAVAfeaDPEAELRQLNRRRVELERALADHESQE 860
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 699 SKVLNELTQLKQLVDA--QKENSVSI--TEHLQ-VITTLRTAAKEMEEKISNLKEH-------------LASKEVEVAKL 760
Cdd:PRK04863 861 QQQRSQLEQAKEGLSAlnRLLPRLNLlaDETLAdRVEEIREQLDEAEEAKRFVQQHgnalaqlepivsvLQSDPEQFEQL 940
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 761 EKQLLEEKA----------AMTDAMVPRS--SYEKLQSSLESEvSVLASKLKESVKEKEkvhSEVAQIRSEVSQVK---R 825
Cdd:PRK04863 941 KQDYQQAQQtqrdakqqafALTEVVQRRAhfSYEDAAEMLAKN-SDLNEKLRQRLEQAE---QERTRAREQLRQAQaqlA 1016
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966946461 826 EKENIQTLLKS----KEQEVNELLQKFQ----QAQEELAEmkRYSESSSKLEE---DKDKKINEMSKEVTKLKEALN 891
Cdd:PRK04863 1017 QYNQVLASLKSsydaKRQMLQELKQELQdlgvPADSGAEE--RARARRDELHArlsANRSRRNQLEKQLTFCEAEMD 1091
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
124-242 |
8.50e-03 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 39.17 E-value: 8.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 124 LQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNVVEALIKKGADL 203
Cdd:COG0666 1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 966946461 204 NLVDSLGHNALHYSKLSENAGIQSLLLSK----ISQDADLKTP 242
Cdd:COG0666 81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAgadvNARDKDGETP 123
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
778-909 |
8.97e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 39.50 E-value: 8.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 778 RSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAE 857
Cdd:COG4372 12 RLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQA 91
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 966946461 858 MKRYSESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQ 909
Cdd:COG4372 92 AQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQS 143
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
607-857 |
9.31e-03 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 39.71 E-value: 9.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 607 LKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDITAEYIHKAEHEKLMQLTNVSRAK 686
Cdd:COG2770 255 LDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLL 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 687 AEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLE 766
Cdd:COG2770 335 LLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVL 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966946461 767 EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVAQIRSEVSQVKREKENIQTLLKSKEQEVNELLQ 846
Cdd:COG2770 415 ALLALALLALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEE 494
|
250
....*....|.
gi 966946461 847 KFQQAQEELAE 857
Cdd:COG2770 495 EEEAGAAAEEL 505
|
|
| |
