Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a ...
88-411
6.16e-127
Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a family of proteins described as retinoic acid-induced protein 16-like proteins. The exact function is not known. The proteins are found from worms to humans.
:
Pssm-ID: 370927 Cd Length: 357 Bit Score: 390.15 E-value: 6.16e-127
Family of unknown function (DUF5917); This short presumed domain is found close to the ...
851-944
4.09e-36
Family of unknown function (DUF5917); This short presumed domain is found close to the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins.
:
Pssm-ID: 466037 Cd Length: 94 Bit Score: 131.54 E-value: 4.09e-36
KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins ...
999-1030
2.70e-05
KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins. It has a conserved KELAA sequence for which it is named.
The actual alignment was detected with superfamily member pfam19311:
Pssm-ID: 466035 Cd Length: 32 Bit Score: 41.71 E-value: 2.70e-05
Neuromodulin; This family consists of several neuromodulin (Axonal membrane protein GAP-43) ...
650-749
1.35e-04
Neuromodulin; This family consists of several neuromodulin (Axonal membrane protein GAP-43) sequences and is found in conjunction with pfam00612. GAP-43 is a neuronal calmodulin-binding phosphoprotein that is concentrated in growth cones and pre-synaptic terminals.
The actual alignment was detected with superfamily member pfam06614:
Pssm-ID: 461961 [Multi-domain] Cd Length: 175 Bit Score: 43.61 E-value: 1.35e-04
Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a ...
88-411
6.16e-127
Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a family of proteins described as retinoic acid-induced protein 16-like proteins. The exact function is not known. The proteins are found from worms to humans.
Pssm-ID: 370927 Cd Length: 357 Bit Score: 390.15 E-value: 6.16e-127
Family of unknown function (DUF5917); This short presumed domain is found close to the ...
851-944
4.09e-36
Family of unknown function (DUF5917); This short presumed domain is found close to the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins.
Pssm-ID: 466037 Cd Length: 94 Bit Score: 131.54 E-value: 4.09e-36
KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins ...
999-1030
2.70e-05
KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins. It has a conserved KELAA sequence for which it is named.
Pssm-ID: 466035 Cd Length: 32 Bit Score: 41.71 E-value: 2.70e-05
Neuromodulin; This family consists of several neuromodulin (Axonal membrane protein GAP-43) ...
650-749
1.35e-04
Neuromodulin; This family consists of several neuromodulin (Axonal membrane protein GAP-43) sequences and is found in conjunction with pfam00612. GAP-43 is a neuronal calmodulin-binding phosphoprotein that is concentrated in growth cones and pre-synaptic terminals.
Pssm-ID: 461961 [Multi-domain] Cd Length: 175 Bit Score: 43.61 E-value: 1.35e-04
Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a ...
88-411
6.16e-127
Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a family of proteins described as retinoic acid-induced protein 16-like proteins. The exact function is not known. The proteins are found from worms to humans.
Pssm-ID: 370927 Cd Length: 357 Bit Score: 390.15 E-value: 6.16e-127
Family of unknown function (DUF5917); This short presumed domain is found close to the ...
851-944
4.09e-36
Family of unknown function (DUF5917); This short presumed domain is found close to the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins.
Pssm-ID: 466037 Cd Length: 94 Bit Score: 131.54 E-value: 4.09e-36
KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins ...
999-1030
2.70e-05
KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins. It has a conserved KELAA sequence for which it is named.
Pssm-ID: 466035 Cd Length: 32 Bit Score: 41.71 E-value: 2.70e-05
Neuromodulin; This family consists of several neuromodulin (Axonal membrane protein GAP-43) ...
650-749
1.35e-04
Neuromodulin; This family consists of several neuromodulin (Axonal membrane protein GAP-43) sequences and is found in conjunction with pfam00612. GAP-43 is a neuronal calmodulin-binding phosphoprotein that is concentrated in growth cones and pre-synaptic terminals.
Pssm-ID: 461961 [Multi-domain] Cd Length: 175 Bit Score: 43.61 E-value: 1.35e-04
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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Functional characterization of the conserved domain architecture found on the query.
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This image shows a graphical summary of conserved domains identified on the query sequence.
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if a domain or superfamily has been annotated with functional sites (conserved features),
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click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.
The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
Click on the domain model's accession number to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.
To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page,
or click on the triangles, if present, that represent functional sites (conserved features)
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Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence.
(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
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(labeled illustration) Four types of hits can be shown, as available,
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specific hits meet or exceed a domain-specific e-value threshold
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and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
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Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool
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