|
Name |
Accession |
Description |
Interval |
E-value |
| FAM184 |
pfam15665 |
Family with sequence similarity 184, A and B; The function of FAM184 is not known. |
57-267 |
9.16e-76 |
|
Family with sequence similarity 184, A and B; The function of FAM184 is not known.
Pssm-ID: 464788 [Multi-domain] Cd Length: 211 Bit Score: 248.42 E-value: 9.16e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 57 VIYALNTKNDEHESAIQALKDAHEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLEASLEDHIKMKQQALTEFEAYK 136
Cdd:pfam15665 1 VIYALNTKNDEHEAEIQALKEAHEEEIQQILAETREKILQYKSKIGEELDLKRRIQTLEESLEQHERMKRQALTEFEQYK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 137 HRVEDMQLCAEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLRTAHRREIQELLKSQQDHSASVN 216
Cdd:pfam15665 81 RRVEERELKAEAEHRQRVVELSREVEEAKRAFEEKLESFEQLQAQFEQEKRKALEELRAKHRQEIQELLTTQRAQSASSL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 966941256 217 KGQEKAEELHRMEVESLNKMLEELRLEQKKLIEDYEGKLNKAQSFYERELD 267
Cdd:pfam15665 161 AEQEKLEELHKAELESLRKEVEDLRKEKKKLAEEYEQKLSKAQAFYERELE 211
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
364-964 |
4.33e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 77.28 E-value: 4.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 364 VESELAAARERLQQQAS---------------DLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQ 428
Cdd:COG1196 194 ILGELERQLEPLERQAEkaeryrelkeelkelEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 429 SKTQSLDEEQKQQILELEKKVSEAKRTQQEyyERELKNLQNRLEEEVTQLNEAHSKTLEELAwkhhmaieavhsnairdk 508
Cdd:COG1196 274 LELEELELELEEAQAEEYELLAELARLEQD--IARLEERRRELEERLEELEEELAELEEELE------------------ 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 509 kKLQMELEEQhNKEKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQT 588
Cdd:COG1196 334 -ELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 589 ELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEDEKLKVDKMAHDLEIKwtENLRQECSKLREELRLQHEEDKK 668
Cdd:COG1196 412 LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA--ELLEEAALLEAALAELLEELAEA 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 669 SAMSQLLQLKEREKNAARDSWQKKveDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHK 748
Cdd:COG1196 490 AARLLLLLEAEADYEGFLEGVKAA--LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLK 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 749 SLKEAhVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSEL 828
Cdd:COG1196 568 AAKAG-RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 829 NHQHAAAIDLLRHNhhQELAAAKMELERSIDISRRQSKEHMCRITDLQEELRHREHHISELDKEVQHLHENISALTKELE 908
Cdd:COG1196 647 REVTLEGEGGSAGG--SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 966941256 909 FKGKEILRIRSESNQQiRLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKL 964
Cdd:COG1196 725 ALEEQLEAEREELLEE-LLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
245-829 |
3.79e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.20 E-value: 3.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 245 KKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLD 324
Cdd:COG1196 216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 325 KCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLvlkashigmlqatqmtqevtiK 404
Cdd:COG1196 296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL---------------------E 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 405 DLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEyyERELKNLQNRLEEEVTQLNEAHSK 484
Cdd:COG1196 355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA--EEALLERLERLEEELEELEEALAE 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 485 TLEELAwkhhmaieavhsnAIRDKKKLQMELEEQHNKEKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGRLQDLVRK 564
Cdd:COG1196 433 LEEEEE-------------EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 565 SEQGLGSAEG-LIASLQDSQERLQTELDLTKDSLKETKDALLNVEGELEQERqQHEETIAAMKEDEKLK----------- 632
Cdd:COG1196 500 EADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI-VVEDDEVAAAAIEYLKaakagratflp 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 633 VDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKEREKNAARDSWQKKVEDLLNQISLLKQNLEIQLS 712
Cdd:COG1196 579 LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 713 QSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHR 792
Cdd:COG1196 659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738
|
570 580 590
....*....|....*....|....*....|....*....
gi 966941256 793 ESMEGFRIEMEQELQTLRFELEDEG--KAMLASLRSELN 829
Cdd:COG1196 739 EELLEEEELLEEEALEELPEPPDLEelERELERLEREIE 777
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
166-703 |
3.70e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 70.74 E-value: 3.70e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 166 RKFEEKLRsfgQLQVQFEKDKRLALEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELhRMEVESLNKMLEELRLEQK 245
Cdd:COG1196 216 RELKEELK---ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL-RLELEELELELEEAQAEEY 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 246 KL---IEDYEGKLNKAQ---SFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEA 319
Cdd:COG1196 292 ELlaeLARLEQDIARLEerrRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 320 GSLLDKCQKL----------QTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHI 389
Cdd:COG1196 372 AELAEAEEELeelaeelleaLRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 390 GMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQ------------ 457
Cdd:COG1196 452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavavlig 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 458 --EYYERELKN-LQNRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMELEEQHNKEKLNLEEDKNQLQ 534
Cdd:COG1196 532 veAAYEAALEAaLAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 535 QELENL--KEVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKETKDALLnvEGELE 612
Cdd:COG1196 612 DARYYVlgDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL--AERLA 689
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 613 QERQQHEETIAAMKEDEKLKVDKMAHDLEIKwTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKEREKNAARDSWQKK 692
Cdd:COG1196 690 EEELELEEALLAEEEEERELAEAEEERLEEE-LEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768
|
570
....*....|.
gi 966941256 693 VEDLLNQISLL 703
Cdd:COG1196 769 LERLEREIEAL 779
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
49-708 |
9.09e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 69.71 E-value: 9.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 49 KKIAQLTKVIYALNTKNDEHESAIQALKDAHEEEIQQILAETREKILQYKSKV----TEELDLRRKIQVLEASLEDHIKM 124
Cdd:TIGR02169 244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIgeleAEIASLERSIAEKERELEDAEER 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 125 KQQALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSR------EVEEIRRKFEEKLRSFGQLQVQFeKDKRLALEDL---RT 195
Cdd:TIGR02169 324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEyaelkeELEDLRAELEEVDKEFAETRDEL-KDYREKLEKLkreIN 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 196 AHRREIQELLKSQQ------------------DHSASVNKGQEKAEELHRME--VESLNKMLEELRLEQKKLIEDYEgKL 255
Cdd:TIGR02169 403 ELKRELDRLQEELQrlseeladlnaaiagieaKINELEEEKEDKALEIKKQEwkLEQLAADLSKYEQELYDLKEEYD-RV 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 256 NKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKtIGKLKTELQMVQDEAGSlldkcQKLQTALAT 335
Cdd:TIGR02169 482 EKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQ-LGSVGERYATAIEVAAG-----NRLNNVVVE 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 336 AENNVQGLQKQLDDAKEGEMALL------SKHKEVE-----------------------------------SELAAARE- 373
Cdd:TIGR02169 556 DDAVAKEAIELLKRRKAGRATFLplnkmrDERRDLSilsedgvigfavdlvefdpkyepafkyvfgdtlvvEDIEAARRl 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 374 ----RLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTqsldEEQKQQILELEKKV 449
Cdd:TIGR02169 636 mgkyRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL----RRIENRLDELSQEL 711
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 450 SEAKRTQQEYYER--ELKNLQNRLEEEVTQLNEAHSKTLEELAwkhhmaieavhsNAIRDKKKLQMELEEqhnkeklnLE 527
Cdd:TIGR02169 712 SDASRKIGEIEKEieQLEQEEEKLKERLEELEEDLSSLEQEIE------------NVKSELKELEARIEE--------LE 771
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 528 EDKNQLQQELENLK--------EVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKE 599
Cdd:TIGR02169 772 EDLHKLEEALNDLEarlshsriPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKS 851
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 600 TKDALLNVEGELEQERQQHEETIAAMKEDEK----LKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLL 675
Cdd:TIGR02169 852 IEKEIENLNGKKEELEEELEELEAALRDLESrlgdLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE 931
|
730 740 750
....*....|....*....|....*....|...
gi 966941256 676 QLKEREKNAARDSWQKKVEDLLNQISLLKQNLE 708
Cdd:TIGR02169 932 ELSEIEDPKGEDEEIPEEELSLEDVQAELQRVE 964
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
64-625 |
1.52e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.81 E-value: 1.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 64 KNDEHESAIQALKDAHEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLEASLEDHIKMKQQALTEFEAYKHRVEDMQ 143
Cdd:COG1196 250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 144 LcAEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLRTAHRREIQEL-LKSQQDHSASVNKGQEKA 222
Cdd:COG1196 330 E-ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLeALRAAAELAAQLEELEEA 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 223 EELHRMEVESLNKMLEELRLEQKKLIEDYEGKLNKAQSFYERELDTLKRSQLfTAESLQASKEKEADLRKEFQGQEAILR 302
Cdd:COG1196 409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA-LLELLAELLEEAALLEAALAELLEELA 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 303 KTIGKLKTELQMVQDEAGSLLDKcqKLQTALATAENNVQGLQKQLDDAKEGEMALlskhkeVESELAAARERLQQQASDL 382
Cdd:COG1196 488 EAAARLLLLLEAEADYEGFLEGV--KAALLLAGLRGLAGAVAVLIGVEAAYEAAL------EAALAAALQNIVVEDDEVA 559
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 383 VLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQE-YYE 461
Cdd:COG1196 560 AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAlRRA 639
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 462 RELKNLQNRLEEEVTQLNEAHSKTLEElawkhhmaiEAVHSNAIRDKKKLQMELEEQHNKEKLNLEEDKNQLQQELENLK 541
Cdd:COG1196 640 VTLAGRLREVTLEGEGGSAGGSLTGGS---------RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA 710
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 542 EVLEDKLNTANQEIGRLQDLVRKSEQglgsaegliaslqdSQERLQTELDLTKDSLKETKDALLNVEgELEQERQQHEET 621
Cdd:COG1196 711 EAEEERLEEELEEEALEEQLEAEREE--------------LLEELLEEEELLEEEALEELPEPPDLE-ELERELERLERE 775
|
....
gi 966941256 622 IAAM 625
Cdd:COG1196 776 IEAL 779
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
44-545 |
8.31e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 66.50 E-value: 8.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 44 HLKMSKKIAQLTKVIYALNTKNDEHESAIQALKD---AHEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLEASLED 120
Cdd:COG1196 276 LEELELELEEAQAEEYELLAELARLEQDIARLEErrrELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 121 HIKMKQQALTEFEAYKHRVEDMQLcAEAQHVQRIVTMSREVEEIRRKFEEKLRsfgqlQVQFEKDKRLALEDLRTAHRRE 200
Cdd:COG1196 356 AEAELAEAEEALLEAEAELAEAEE-ELEELAEELLEALRAAAELAAQLEELEE-----AEEALLERLERLEEELEELEEA 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 201 IQELLKSQQDHSASVNKGQEKAEELHRmEVESLNKMLEELRLEQKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESL 280
Cdd:COG1196 430 LAELEEEEEEEEEALEEAAEEEAELEE-EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 281 QASKEKEADLRKEFQGQEAILRKTIGKLKTEL---------QMVQDEAGSLLDKCQKLQTAL---ATAENNVQGLQKQLD 348
Cdd:COG1196 509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALeaalaaalqNIVVEDDEVAAAAIEYLKAAKagrATFLPLDKIRARAAL 588
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 349 DAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQmTQEVTIKDLESEKSRANERLSQLEEERAFLQ 428
Cdd:COG1196 589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL-RRAVTLAGRLREVTLEGEGGSAGGSLTGGSR 667
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 429 SKTQSLDEEQKQQILELEKKVSEAKRTQQEYYERELKNLQNRLEEEVTQLNEAHSKTLEELAwkhhmaiEAVHSNAIRDK 508
Cdd:COG1196 668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ-------LEAEREELLEE 740
|
490 500 510
....*....|....*....|....*....|....*..
gi 966941256 509 KKLQMELEEQHNKEKLNLEEDKNQLQQELENLKEVLE 545
Cdd:COG1196 741 LLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
278-985 |
2.54e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.08 E-value: 2.54e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 278 ESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMAL 357
Cdd:TIGR02168 242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 358 -------LSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSK 430
Cdd:TIGR02168 322 eaqleelESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 431 TQSLDEEQKQQILELEKKVSEAKRTQQEYYERELKNLQNRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKK 510
Cdd:TIGR02168 402 IERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAE 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 511 LQmelEEQHNKEKLNLEEDKNQLQQELENLKEVLeDKLNTANQEIGRLQDLVrKSEQGLGSA------EGLIASLQDSQE 584
Cdd:TIGR02168 482 RE---LAQLQARLDSLERLQENLEGFSEGVKALL-KNQSGLSGILGVLSELI-SVDEGYEAAieaalgGRLQAVVVENLN 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 585 RLQTELDLTKDS---------LKETKDALLNVEGELEQERQQHEETIAAMKEDEKLKVDKMAHDL--EIKWTENLRQ--- 650
Cdd:TIGR02168 557 AAKKAIAFLKQNelgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNale 636
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 651 ECSKLREELRLQHEEDKKSAMSQLLQLKEREKNAARDSWQKKVEDLLNQISLLKQ---NLEIQLSQSQTSLQQLQAQFTQ 727
Cdd:TIGR02168 637 LAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEkiaELEKALAELRKELEELEEELEQ 716
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 728 ERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEgfriEMEQELQ 807
Cdd:TIGR02168 717 LRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIE 792
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 808 TLRFELEDEgKAMLASLRSELNHQHAAAIDLLrhNHHQELAAAKMELERSIDISRRQSKEHMCRITDLQEELRHREHHIS 887
Cdd:TIGR02168 793 QLKEELKAL-REALDELRAELTLLNEEAANLR--ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 888 ELDKEVQHLhENISALTKELEFKGKEILRIRSESNQQIRLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIED 967
Cdd:TIGR02168 870 ELESELEAL-LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE 948
|
730
....*....|....*...
gi 966941256 968 nkfYQLELVNRETNFNKV 985
Cdd:TIGR02168 949 ---YSLTLEEAEALENKI 963
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
161-956 |
4.83e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.92 E-value: 4.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 161 VEEIRRKFEEKLRSfgqLQVQFEKDKRLAL--EDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKM-- 236
Cdd:TIGR02168 191 LEDILNELERQLKS---LERQAEKAERYKElkAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELee 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 237 -LEELRLEQ---KKLIEDYEGKLNKAQSfyerELDTLKRSQLFTAESLQASKEKeadlRKEFQGQEAILRKTIGKLKTEL 312
Cdd:TIGR02168 268 kLEELRLEVselEEEIEELQKELYALAN----EISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEEL 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 313 QMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEgemallsKHKEVESELAAARERLQQQASDLVLKASHIGML 392
Cdd:TIGR02168 340 AELEEKLEELKEELESLEAELEELEAELEELESRLEELEE-------QLETLRSKVAQLELQIASLNNEIERLEARLERL 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 393 QATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYERELKNLQNRLE 472
Cdd:TIGR02168 413 EDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 473 EEVTQLNEAHSKTLEELAWKHHM----AIEAVHSNAIRDKKKLQMELEEQHNKEKLNLE-EDKNQLQQELENLKE----- 542
Cdd:TIGR02168 493 SLERLQENLEGFSEGVKALLKNQsglsGILGVLSELISVDEGYEAAIEAALGGRLQAVVvENLNAAKKAIAFLKQnelgr 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 543 --VLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQ-------------ERLQTELDLTKDSLKE----TKDA 603
Cdd:TIGR02168 573 vtFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvDDLDNALELAKKLRPGyrivTLDG 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 604 LL---------------NVEGELEQERQQHEETIAAMKEDEKLKVDKMAhDLEIKwTENLRQECSKLREELRlQHEEDKK 668
Cdd:TIGR02168 653 DLvrpggvitggsaktnSSILERRREIEELEEKIEELEEKIAELEKALA-ELRKE-LEELEEELEQLRKELE-ELSRQIS 729
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 669 SAMSQLLQLKEREKNAA--RDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQ------AQFTQERQRLTQELEELE 740
Cdd:TIGR02168 730 ALRKDLARLEAEVEQLEerIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEeleaqiEQLKEELKALREALDELR 809
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 741 eqhqQRHKSLKEahvlAFQTMEEEKEKEQRALenHLQQKHSAELQSLKDAHRESMEGFRIEMEqELQTLRFELEDEGKAM 820
Cdd:TIGR02168 810 ----AELTLLNE----EAANLRERLESLERRI--AATERRLEDLEEQIEELSEDIESLAAEIE-ELEELIEELESELEAL 878
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 821 LASLRSelnhqhaaaidllrhnhhqeLAAAKMELERSIDISRRQSKEHMCRITDLQEELRHREHHISELDKEVQhlheni 900
Cdd:TIGR02168 879 LNERAS--------------------LEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE------ 932
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*..
gi 966941256 901 saltkELEFKGKEILRIRSEsNQQIRLEEMEEKYLMRESKPEDIQM-ITELKAMLTE 956
Cdd:TIGR02168 933 -----GLEVRIDNLQERLSE-EYSLTLEEAEALENKIEDDEEEARRrLKRLENKIKE 983
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
44-680 |
4.38e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.84 E-value: 4.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 44 HLKMSKKIAQLTKVIYALNTKNDEHESAIQALKDAhEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLEASLEDHIK 123
Cdd:TIGR02168 276 VSELEEEIEELQKELYALANEISRLEQQKQILRER-LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 124 MKQQALTEFEAYKHRVEDMQLCAEAQHVQ-----------------RIVTMSREVEEIRRKFEEKLRSFGQLQVQFEK-- 184
Cdd:TIGR02168 355 SLEAELEELEAELEELESRLEELEEQLETlrskvaqlelqiaslnnEIERLEARLERLEDRRERLQQEIEELLKKLEEae 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 185 ---------DKRLALEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELHRM--EVESLNKMLEELR---------LEQ 244
Cdd:TIGR02168 435 lkelqaeleELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLqaRLDSLERLQENLEgfsegvkalLKN 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 245 KKLIEDYEGKLNKAQSF---YERELDTL--KRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGK----LKTELQMV 315
Cdd:TIGR02168 515 QSGLSGILGVLSELISVdegYEAAIEAAlgGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKgteiQGNDREIL 594
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 316 QDEAGsLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQAT 395
Cdd:TIGR02168 595 KNIEG-FLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSIL 673
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 396 QMTQEvtIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYyeRELKNLQNRLEEEV 475
Cdd:TIGR02168 674 ERRRE--IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDL--ARLEAEVEQLEERI 749
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 476 TQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMELE-EQHNKEKLNLEEDKNQLQQELENLKEVLEDKLNTANQ- 553
Cdd:TIGR02168 750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQiEQLKEELKALREALDELRAELTLLNEEAANLRERLESl 829
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 554 --EIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKetkdallnvegELEQERQQHEETIAAMKEDEKL 631
Cdd:TIGR02168 830 erRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE-----------ALLNERASLEEALALLRSELEE 898
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 966941256 632 KVDKMaHDLEIKWTEnLRQECSKLREELRlQHEEDKKSAMSQLLQLKER 680
Cdd:TIGR02168 899 LSEEL-RELESKRSE-LRRELEELREKLA-QLELRLEGLEVRIDNLQER 944
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
236-881 |
2.33e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 58.39 E-value: 2.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 236 MLEELRLEQ--KKLIEDYEgKLNKAqsfyERELDTLKRsQLFTAESLQASKEKEADLRKEFQGQEAIL--------RKTI 305
Cdd:COG4913 217 MLEEPDTFEaaDALVEHFD-DLERA----HEALEDARE-QIELLEPIRELAERYAAARERLAELEYLRaalrlwfaQRRL 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 306 GKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLskhkevESELAAARERLQQQASDLvlk 385
Cdd:COG4913 291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQL------EREIERLERELEERERRR--- 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 386 ASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAflqsktqSLDEEQKQQILELEKKVSEAKRTQQEYyeRELK 465
Cdd:COG4913 362 ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE-------ALEEALAEAEAALRDLRRELRELEAEI--ASLE 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 466 NLQNRLEEEVTQLNEAHSKTL------------------EELAWkhHMAIEAV-HS-------------------NAIRD 507
Cdd:COG4913 433 RRKSNIPARLLALRDALAEALgldeaelpfvgelievrpEEERW--RGAIERVlGGfaltllvppehyaaalrwvNRLHL 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 508 KKKLQMELEEQHNKEKLNLEEDKNQLQQELenlkEVLEDKL-NTANQEIGRLQDLV-----------RKS--EQGLGSAE 573
Cdd:COG4913 511 RGRLVYERVRTGLPDPERPRLDPDSLAGKL----DFKPHPFrAWLEAELGRRFDYVcvdspeelrrhPRAitRAGQVKGN 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 574 GLIASLQDSQ----------------ERLQTELDLTKDSLKETKDALLNVEGELE--QERQQHEETIAAMKEDEklkVDK 635
Cdd:COG4913 587 GTRHEKDDRRrirsryvlgfdnraklAALEAELAELEEELAEAEERLEALEAELDalQERREALQRLAEYSWDE---IDV 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 636 MAHDLEIkwtENLRQEcsklREELRlqheedkkSAMSQLLQLKER--EKNAARDSWQKKVEDLLNQISLLKQNLEiqlsq 713
Cdd:COG4913 664 ASAEREI---AELEAE----LERLD--------ASSDDLAALEEQleELEAELEELEEELDELKGEIGRLEKELE----- 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 714 sqtslqqlqaQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLafQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRE 793
Cdd:COG4913 724 ----------QAEEELDELQDRLEAAEDLARLELRALLEERFA--AALGDAVERELRENLEERIDALRARLNRAEEELER 791
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 794 SMEGFRIEMEQELQTLRFELEDEGK--AMLASLRSE-LNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRqskehmc 870
Cdd:COG4913 792 AMRAFNREWPAETADLDADLESLPEylALLDRLEEDgLPEYEERFKELLNENSIEFVADLLSKLRRAIREIKE------- 864
|
730
....*....|.
gi 966941256 871 RITDLQEELRH 881
Cdd:COG4913 865 RIDPLNDSLKR 875
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
48-779 |
4.42e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 57.67 E-value: 4.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 48 SKKIAQLTKVIYALNTKNDEHESAIQALKDAHEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLEASLEDHIKMKQQ 127
Cdd:pfam02463 263 EEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEK 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 128 ALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLRTAHRREIQE-LLK 206
Cdd:pfam02463 343 ELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEdLLK 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 207 SQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRL------EQKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESL 280
Cdd:pfam02463 423 EEKKEELEILEEEEESIELKQGKLTEEKEELEKQELkllkdeLELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKE 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 281 QASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQD---------------EAGSLLDKCQKLQTALATAENNVQGLQK 345
Cdd:pfam02463 503 SKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEnykvaistavivevsATADEVEERQKLVRALTELPLGARKLRL 582
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 346 QLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERA 425
Cdd:pfam02463 583 LIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKS 662
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 426 FLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYERELKNLQNRLEEEVTQLNEAHSKTLEELAwKHHMAIEAVHSNAI 505
Cdd:pfam02463 663 EVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV-QEAQDKINEELKLL 741
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 506 RDKKKLQMELEEQHNKEKLNLEEDKNQLQQELENLKEVLE-DKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQE 584
Cdd:pfam02463 742 KQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREkTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQ 821
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 585 RLQTELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEDEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHE 664
Cdd:pfam02463 822 LLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKE 901
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 665 EDKKSAMSQLLQLKEREKNAARDSWQKKVEDLLNQI--SLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQ 742
Cdd:pfam02463 902 LEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPeeLLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIE 981
|
730 740 750
....*....|....*....|....*....|....*..
gi 966941256 743 HQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQK 779
Cdd:pfam02463 982 EFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
237-625 |
4.98e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 4.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 237 LEELRLEQKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAiLRKTIGKLKTELQMVQ 316
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELE 760
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 317 DEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLvlkashiGMLQATQ 396
Cdd:TIGR02168 761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL-------ESLERRI 833
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 397 MTQEVTIKDLEseksranERLSQLEEERAFLQSKTQSLDEEQKQQILELEkKVSEAKRTQQEyyerELKNLQNRLEEEVT 476
Cdd:TIGR02168 834 AATERRLEDLE-------EQIEELSEDIESLAAEIEELEELIEELESELE-ALLNERASLEE----ALALLRSELEELSE 901
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 477 QLNEahsktleelawkhhmaieavHSNAIRDKKKLQMELEEQHNKEKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIG 556
Cdd:TIGR02168 902 ELRE--------------------LESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALEN 961
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966941256 557 RLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELdltkDSLKETKDALLNVEGELEQERQQHEETIAAM 625
Cdd:TIGR02168 962 KIEDDEEEARRRLKRLENKIKELGPVNLAAIEEY----EELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
28-474 |
1.17e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 56.30 E-value: 1.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 28 AAAQLAGHSMDYSQEMHLKMSKKIAQLTKVIYALNTKNDEHESAIQALKDAHE-----EEIQQIlAETREKILQYKSKVT 102
Cdd:PTZ00121 1350 AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdkkkaDELKKA-AAAKKKADEAKKKAE 1428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 103 EEL---DLRRKIQvlEASLEDHIKMKQQALTEFEAYKHRVEDMQlcaEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQ 179
Cdd:PTZ00121 1429 EKKkadEAKKKAE--EAKKADEAKKKAEEAKKAEEAKKKAEEAK---KADEAKKKAEEAKKADEAKKKAEEAKKKADEAK 1503
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 180 vQFEKDKRLALEDLRTAHRREIQELLKSQQDHSASVNKGQE---KAEELHRmeVESLNKMLEELRLEQKKLIE-DYEGKL 255
Cdd:PTZ00121 1504 -KAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEekkKADELKK--AEELKKAEEKKKAEEAKKAEeDKNMAL 1580
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 256 NKAQSFYERELdtlKRSQLFTAESLQASKEKEADLRKEfqgQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAT 335
Cdd:PTZ00121 1581 RKAEEAKKAEE---ARIEEVMKLYEEEKKMKAEEAKKA---EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKK 1654
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 336 AENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASdlvlkashigmlQATQMTQevtIKDLESEKSRANE 415
Cdd:PTZ00121 1655 AEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE------------EAKKAEE---LKKKEAEEKKKAE 1719
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 966941256 416 RLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYERELKNLQNRLEEE 474
Cdd:PTZ00121 1720 ELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
82-671 |
1.28e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 55.84 E-value: 1.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 82 EIQQILA--ETREKILQ-------YKSKVTEELDLRRKIQVLEASLEDHIKMKQQALTEFEAYKHRVEDMQlcaeaQHVQ 152
Cdd:PRK03918 136 EIDAILEsdESREKVVRqilglddYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVL-----REIN 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 153 RIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEdlRTAHRREIQELLKSQQDHSASVNKGQEKAEELHRmEVES 232
Cdd:PRK03918 211 EISSELPELREELEKLEKEVKELEELKEEIEELEKELES--LEGSKRKLEEKIRELEERIEELKKEIEELEEKVK-ELKE 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 233 LNKMLEELRlEQKKLIEDYEGKLNKAqsfyERELDTLKRSQLFTAESLQASKEKEADLrKEFQGQEAILRKTIGKLKTEL 312
Cdd:PRK03918 288 LKEKAEEYI-KLSEFYEEYLDELREI----EKRLSRLEEEINGIEERIKELEEKEERL-EELKKKLKELEKRLEELEERH 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 313 QMVQdEAGSLLDKCQKLQTALAtaENNVQGLQKQLDDAKEgemallsKHKEVESELAAARERLQQQASDLVLKASHIGML 392
Cdd:PRK03918 362 ELYE-EAKAKKEELERLKKRLT--GLTPEKLEKELEELEK-------AKEEIEEEISKITARIGELKKEIKELKKAIEEL 431
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 393 QATQMTQEVTIKDLESE-----KSRANERLSQLEEERAFLQSKTQSLDEEQKqqilELEKKVSEAKR-TQQEYYERELKN 466
Cdd:PRK03918 432 KKAKGKCPVCGRELTEEhrkelLEEYTAELKRIEKELKEIEEKERKLRKELR----ELEKVLKKESElIKLKELAEQLKE 507
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 467 LQNRLE----EEVTQLNEAHSKTLEELAwkhhmAIEAVHSNAIRDKKKLqmeleEQHNKEKLNLEEDKNQLQQELENLKE 542
Cdd:PRK03918 508 LEEKLKkynlEELEKKAEEYEKLKEKLI-----KLKGEIKSLKKELEKL-----EELKKKLAELEKKLDELEEELAELLK 577
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 543 VLEDK----LNTANQEIGRLQDLVRKSEQgLGSAEGLIASLQDSQERLQTELDLTKDSLKETKDALLNVEGELEQERQQH 618
Cdd:PRK03918 578 ELEELgfesVEELEERLKELEPFYNEYLE-LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY 656
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 966941256 619 EETIAAMKEDEKLKVDKMAHDL--EIKWTENLRQECSKLREELRLQHEEDKKSAM 671
Cdd:PRK03918 657 SEEEYEELREEYLELSRELAGLraELEELEKRREEIKKTLEKLKEELEEREKAKK 711
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
91-451 |
1.40e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.84 E-value: 1.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 91 REKILQYKSKVTEELDLRRKIQVLEASLEDHIKMKQQALTEFEAYKHRVEDMQlcaeaqhvQRIVTMSREVEEIRRKFEE 170
Cdd:TIGR02169 663 RGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS--------RKIGEIEKEIEQLEQEEEK 734
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 171 KLRSFGQLQVQFEKdkrlaLEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELHRM-------EVESLNKMLEELRLE 243
Cdd:TIGR02169 735 LKERLEELEEDLSS-----LEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARlshsripEIQAELSKLEEEVSR 809
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 244 QKKLIEDYEGKLNKAQSFYE-------------RELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKT 310
Cdd:TIGR02169 810 IEARLREIEQKLNRLTLEKEylekeiqelqeqrIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKK 889
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 311 ELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESE---------LAAARERLQQQASD 381
Cdd:TIGR02169 890 ERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpeeelsledVQAELQRVEEEIRA 969
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966941256 382 LvlkaSHIGMLqatqmtqevTIKDLESEKSRANE---RLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSE 451
Cdd:TIGR02169 970 L----EPVNML---------AIQEYEEVLKRLDElkeKRAKLEEERKAILERIEEYEKKKREVFMEAFEAINE 1029
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
85-950 |
1.92e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 55.36 E-value: 1.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 85 QILAETREKILQYKSKVTEELDLRRKIQVLEASLEDHIKMKQQALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSREVEEI 164
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 165 RRKFEEKLrSFGQLQVQFEKDKRLALEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLEQ 244
Cdd:pfam02463 249 EQEEIESS-KQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAE 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 245 KKLIEDYEGKLNKAQSFYERELDTLKRsqlftaeslqasKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLD 324
Cdd:pfam02463 328 KELKKEKEEIEELEKELKELEIKREAE------------EEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 325 KCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEV--- 401
Cdd:pfam02463 396 ELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDllk 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 402 TIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYE-----RELKNLQNRLEEEVT 476
Cdd:pfam02463 476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGvavenYKVAISTAVIVEVSA 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 477 QLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMELEEQHNKEKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIG 556
Cdd:pfam02463 556 TADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELT 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 557 RLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEDEKLKVDKM 636
Cdd:pfam02463 636 KLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKL 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 637 AHDLEIKWTENLRQECSKLREELRLQH--------------------EEDKKSAMSQLLQLKEREKNAARDSWQKKVEDL 696
Cdd:pfam02463 716 KLEAEELLADRVQEAQDKINEELKLLKqkideeeeeeeksrlkkeekEEEKSELSLKEKELAEEREKTEKLKVEEEKEEK 795
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 697 LNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHL 776
Cdd:pfam02463 796 LKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLK 875
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 777 QQKHSAELQSLKDAHREsMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHqhaaaIDLLRHNHHQELAAAKMELER 856
Cdd:pfam02463 876 EEELEEQKLKDELESKE-EKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAE-----ILLKYEEEPEELLLEEADEKE 949
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 857 SIDISRRQSKEHMCRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIRLEEMEEKYLM 936
Cdd:pfam02463 950 KEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSI 1029
|
890
....*....|....
gi 966941256 937 RESKPEDIQMITEL 950
Cdd:pfam02463 1030 NKGWNKVFFYLELG 1043
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
35-589 |
2.01e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 55.51 E-value: 2.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 35 HSMDYSQEMHLK-----MSKKIAQLTKVIYALNTKNDEHESAIQALKDAHEEEIQQILAETREKILQYKSKVTEEL---- 105
Cdd:pfam15921 205 YEHDSMSTMHFRslgsaISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEItglt 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 106 ----DLRRKIQVLEASLEdhiKMKQQALTEFEAYKHRVEDM-----QLCAEAQHVQR------------IVTMSREVEEI 164
Cdd:pfam15921 285 ekasSARSQANSIQSQLE---IIQEQARNQNSMYMRQLSDLestvsQLRSELREAKRmyedkieelekqLVLANSELTEA 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 165 RRKFEEKLRSFGQLQVQFEKdkrlALEDLrtaHRREIQ-ELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLE 243
Cdd:pfam15921 362 RTERDQFSQESGNLDDQLQK----LLADL---HKREKElSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEAL 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 244 QKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAE--------------------SLQASKEKEADLRKEFQGQEAILRK 303
Cdd:pfam15921 435 LKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQlestkemlrkvveeltakkmTLESSERTVSDLTASLQEKERAIEA 514
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 304 T---IGKLKT-------ELQMVQDEAGSLLD---KCQKLQTALATAENNVQGLQKQLddakEGEMALLSKHKEVESELAA 370
Cdd:pfam15921 515 TnaeITKLRSrvdlklqELQHLKNEGDHLRNvqtECEALKLQMAEKDKVIEILRQQI----ENMTQLVGQHGRTAGAMQV 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 371 ARERLQQQASDLVLKASHIGMLQATQMTQ----EVTIKDLESEKSR----ANERL----------SQLEEERAFLQSKTQ 432
Cdd:pfam15921 591 EKAQLEKEINDRRLELQEFKILKDKKDAKirelEARVSDLELEKVKlvnaGSERLravkdikqerDQLLNEVKTSRNELN 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 433 SLDEEQKQQILELEKKvSEAKRTQQEYYERELKNLQNRLEEEVTQL-----NEAHSKTLeELAWKHHMAIEAVHSNAIRD 507
Cdd:pfam15921 671 SLSEDYEVLKRNFRNK-SEEMETTTNKLKMQLKSAQSELEQTRNTLksmegSDGHAMKV-AMGMQKQITAKRGQIDALQS 748
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 508 KKKLQMELEEQHNKEKLNLEEDKNQLQQELENL---KEVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQE 584
Cdd:pfam15921 749 KIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVateKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828
|
....*
gi 966941256 585 RLQTE 589
Cdd:pfam15921 829 RQEQE 833
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
114-807 |
3.15e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.15 E-value: 3.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 114 LEASLEDHIKMKQQALTEfEAYKHRVEDMQLCAEAQHVQRIVTMSREVEEIRRKFEeklrsfgqlqVQFEKDKRLALEDL 193
Cdd:PTZ00121 1084 KEDNRADEATEEAFGKAE-EAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAED----------ARKAEEARKAEDAK 1152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 194 RTAHRREIQELLKSQQDHSASVNKGQE---KAEELHRmeVESLNKMLEELRLEQKKLIEDYEGKLNKAQSFYERELDTLK 270
Cdd:PTZ00121 1153 RVEIARKAEDARKAEEARKAEDAKKAEaarKAEEVRK--AEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVK 1230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 271 RSQLFTAESLQASKEKE----ADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQ 346
Cdd:PTZ00121 1231 KAEEAKKDAEEAKKAEEernnEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKK 1310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 347 LDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGM---LQATQMTQEVTIKDLESEKSRANERLSQLEEE 423
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAadeAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 424 RAFLQSKTQSldEEQKQQILELEKKVSEAKRTQqeyyerELKnlqnRLEEEVTQLNEAHSKTLEElawkhhmaieavhsn 503
Cdd:PTZ00121 1391 KKADEAKKKA--EEDKKKADELKKAAAAKKKAD------EAK----KKAEEKKKADEAKKKAEEA--------------- 1443
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 504 aiRDKKKLQMELEEQHNKEKLNLEEDKNQLQQELENLKEvledklntanqEIGRLQDLVRKSEQGLGSAEGLiaslqdsq 583
Cdd:PTZ00121 1444 --KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAE-----------EAKKADEAKKKAEEAKKKADEA-------- 1502
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 584 eRLQTELDLTKDSLKETKDALLNVEGELEQERQQHEEtiaAMKEDEKLKVDkmahdlEIKWTENLRQECSKLREELRLQH 663
Cdd:PTZ00121 1503 -KKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE---AKKAEEKKKAD------ELKKAEELKKAEEKKKAEEAKKA 1572
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 664 EEDKKSAMSQLLQLKEREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQH 743
Cdd:PTZ00121 1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL 1652
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966941256 744 QQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQ 807
Cdd:PTZ00121 1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK 1716
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
183-979 |
3.71e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 54.59 E-value: 3.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 183 EKDKRLALEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLEQKKLIEDYEGKLNKAQSFY 262
Cdd:pfam02463 181 ETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEI 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 263 ERELDTLKRSQLFTAESLQASKEKEaDLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQG 342
Cdd:pfam02463 261 EKEEEKLAQVLKENKEEEKEKKLQE-EELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 343 LQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEE 422
Cdd:pfam02463 340 LEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLED 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 423 ERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYERELKNLQNRLEEEV-TQLNEAHSKTLEELAWKHHMAIEAVH 501
Cdd:pfam02463 420 LLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDlLKETQLVKLQEQLELLLSRQKLEERS 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 502 SNAIRDKKKLQMELEEQHNKEKLNLeedkNQLQQELENLKEVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQD 581
Cdd:pfam02463 500 QKESKARSGLKVLLALIKDGVGGRI----ISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPL 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 582 SQERLQTELDLTKDSLKetkdalLNVEGELEQERQQHEETIAAMKEDEKLKVDKMAHDLEIKWTENLRQECSKLREELRL 661
Cdd:pfam02463 576 GARKLRLLIPKLKLPLK------SIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLR 649
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 662 QHEEDKKSAMSQLLQLKEREKNAARdswQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEE 741
Cdd:pfam02463 650 KGVSLEEGLAEKSEVKASLSELTKE---LLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 742 QHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEM-EQELQTLRFELEDEGKAM 820
Cdd:pfam02463 727 VQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKvEEEKEEKLKAQEEELRAL 806
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 821 LASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHmcRITDLQEELRHREHHISELDKEVQHLHENI 900
Cdd:pfam02463 807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE--ELERLEEEITKEELLQELLLKEEELEEQKL 884
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 901 SALTKELEFKGKEILRIRSESNQQIRLEEMEEKY--LMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNR 978
Cdd:pfam02463 885 KDELESKEEKEKEEKKELEEESQKLNLLEEKENEieERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964
|
.
gi 966941256 979 E 979
Cdd:pfam02463 965 L 965
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
198-618 |
4.38e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.00 E-value: 4.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 198 RREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLEQKKLIEDYEGKLNKAQ---SFYERELDTLKRSQL 274
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEaelAELPERLEELEERLE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 275 FTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAkEGE 354
Cdd:COG4717 157 ELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL-ENE 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 355 MALLSKHKEVESE-----LAAARERLQQQASDLVLKASHIG----------MLQATQMTQEVTIKDLESEKSRANERLSQ 419
Cdd:COG4717 236 LEAAALEERLKEArllllIAAALLALLGLGGSLLSLILTIAgvlflvlgllALLFLLLAREKASLGKEAEELQALPALEE 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 420 LEEERAFLQSKTQSLDEE-QKQQILELEKKVSEAKRTQQEYYERELKNLQNRLEEEVTQL-NEAHSKTLEELAWKHHMAI 497
Cdd:COG4717 316 LEEEELEELLAALGLPPDlSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALlAEAGVEDEEELRAALEQAE 395
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 498 EAVhsNAIRDKKKLQMELEEQHNKEKLNLE-EDKNQLQQELENLK---EVLEDKLNTANQEIGRLQDLVRKSEQGlGSAE 573
Cdd:COG4717 396 EYQ--ELKEELEELEEQLEELLGELEELLEaLDEEELEEELEELEeelEELEEELEELREELAELEAELEQLEED-GELA 472
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 966941256 574 GLIASLQDSQERLQtELDLTKDSLKETKDALLNVEGELEQERQQH 618
Cdd:COG4717 473 ELLQELEELKAELR-ELAEEWAALKLALELLEEAREEYREERLPP 516
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
52-522 |
7.06e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 53.58 E-value: 7.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 52 AQLTKVIYALNTKNDEHE--SAIQALKDAHEEEIQQILAETREKILQYKSKvteeldlRRKIQVLEASLEDHIKMKQQAL 129
Cdd:pfam15921 444 GQMERQMAAIQGKNESLEkvSSLTAQLESTKEMLRKVVEELTAKKMTLESS-------ERTVSDLTASLQEKERAIEATN 516
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 130 TEFEAYKHRV-----EDMQLCAEAQHVQRIVTmsrEVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLRTAHRREIQEL 204
Cdd:pfam15921 517 AEITKLRSRVdlklqELQHLKNEGDHLRNVQT---ECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKA 593
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 205 LKSQQDHSASVNKGQEKA-EELHRMEVESLNKMLEELRLEQKKLIEDYEGKLNKAQSFyERELDTLKRSQLFTAESLQAS 283
Cdd:pfam15921 594 QLEKEINDRRLELQEFKIlKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDI-KQERDQLLNEVKTSRNELNSL 672
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 284 KEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLdDAKEGEM-ALLSKHK 362
Cdd:pfam15921 673 SEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQI-TAKRGQIdALQSKIQ 751
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 363 EVESELAAARER---LQQQASDLVLKASHIGMlQATQMTQEVTIkdLESEKSRANERLSQLEE--ERAFLQ-SKTQSLDE 436
Cdd:pfam15921 752 FLEEAMTNANKEkhfLKEEKNKLSQELSTVAT-EKNKMAGELEV--LRSQERRLKEKVANMEValDKASLQfAECQDIIQ 828
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 437 EQKQQILELE-KKVSEAKRTQQEYYERElKNLQNRLEEEV----TQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKL 511
Cdd:pfam15921 829 RQEQESVRLKlQHTLDVKELQGPGYTSN-SSMKPRLLQPAsftrTHSNVPSSQSTASFLSHHSRKTNALKEDPTRDLKQL 907
|
490
....*....|.
gi 966941256 512 QMELEEQHNKE 522
Cdd:pfam15921 908 LQELRSVINEE 918
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
185-659 |
9.94e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 53.12 E-value: 9.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 185 DKRLALEDLRTaHRREIQELLKSQ------QDHSASVNKGQEKAEELhRMEVESLNKMLE---ELRLEQKKLIEDYEGKL 255
Cdd:PRK02224 173 DARLGVERVLS-DQRGSLDQLKAQieekeeKDLHERLNGLESELAEL-DEEIERYEEQREqarETRDEADEVLEEHEERR 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 256 nkaqsfyeRELDTLKRsqlfTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAG--------------- 320
Cdd:PRK02224 251 --------EELETLEA----EIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGlddadaeavearree 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 321 ------SLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQA 394
Cdd:PRK02224 319 ledrdeELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRE 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 395 TQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDE--EQKQQILELEK--------------KVSEAKRTQQE 458
Cdd:PRK02224 399 RFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARErvEEAEALLEAGKcpecgqpvegsphvETIEEDRERVE 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 459 YYERELKNL---QNRLEEEVTQLNEAHS------------KTLEELAWKHHMAIEAvHSNAIRDKKKLQMELEEQHNKEK 523
Cdd:PRK02224 479 ELEAELEDLeeeVEEVEERLERAEDLVEaedrierleerrEDLEELIAERRETIEE-KRERAEELRERAAELEAEAEEKR 557
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 524 LNLEEDKNQLQQELENLKEvLEDKLNTANQEIGRLQDlVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKETKDA 603
Cdd:PRK02224 558 EAAAEAEEEAEEAREEVAE-LNSKLAELKERIESLER-IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRER 635
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966941256 604 LLNVEGELE--------QERQQHEETIAAMKED-EKLKVDKMAHDLEIKWTENLRQECSKLREEL 659
Cdd:PRK02224 636 KRELEAEFDearieearEDKERAEEYLEQVEEKlDELREERDDLQAEIGAVENELEELEELRERR 700
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
340-660 |
1.52e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.76 E-value: 1.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 340 VQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLEseksranERLSQ 419
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE-------EDLSS 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 420 LEEERAFLQSKTQSLDEEQKQQILELEKkvseakrtqqeyYERELKNLQNRLEEEVTQLNEAHSKTLEElawkHHMAIEA 499
Cdd:TIGR02169 749 LEQEIENVKSELKELEARIEELEEDLHK------------LEEALNDLEARLSHSRIPEIQAELSKLEE----EVSRIEA 812
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 500 VHSNAIRDKKKLQMELEeqhnkeklnLEEDKnqlQQELENLKEVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASL 579
Cdd:TIGR02169 813 RLREIEQKLNRLTLEKE---------YLEKE---IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL 880
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 580 QDSQERLQTELDLTKDSLKETKDALLNVEGELEQERQ---QHEETIAAMKEDEKLKVDKMAHDLEIKWT----ENLRQEC 652
Cdd:TIGR02169 881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKrlsELKAKLEALEEELSEIEDPKGEDEEIPEEelslEDVQAEL 960
|
....*...
gi 966941256 653 SKLREELR 660
Cdd:TIGR02169 961 QRVEEEIR 968
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
231-929 |
1.87e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 52.43 E-value: 1.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 231 ESLNKMLEELRLEqkklIEDYEGKLNKAQSFYERELDTLKRSQL---FTAESLQASKEKEADLRK-EFQGQEAI---LRK 303
Cdd:pfam15921 74 EHIERVLEEYSHQ----VKDLQRRLNESNELHEKQKFYLRQSVIdlqTKLQEMQMERDAMADIRRrESQSQEDLrnqLQN 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 304 TIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKH-------------------KEV 364
Cdd:pfam15921 150 TVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHdsmstmhfrslgsaiskilREL 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 365 ESELAAARERL------------QQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQ 432
Cdd:pfam15921 230 DTEISYLKGRIfpvedqlealksESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQAR 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 433 SLDEEQKQQILELEKKVSEAKRTQQEyyerELKNLQNRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNairdkKKLQ 512
Cdd:pfam15921 310 NQNSMYMRQLSDLESTVSQLRSELRE----AKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLD-----DQLQ 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 513 MELEEQHNKEK-LNLEEDKNQLQQELENLKEV----LEDKLNTANQEIGRLQDLVRK-SEQGLGSAEGLIASLQDSQERL 586
Cdd:pfam15921 381 KLLADLHKREKeLSLEKEQNKRLWDRDTGNSItidhLRRELDDRNMEVQRLEALLKAmKSECQGQMERQMAAIQGKNESL 460
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 587 Q------TELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEDEKL------KVDKMAH--DLEIKWTENLRQEC 652
Cdd:pfam15921 461 EkvssltAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAieatnaEITKLRSrvDLKLQELQHLKNEG 540
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 653 SKLR------EELRLQHEEDKK---------SAMSQLLQLKEREKNAARDSwQKKVEDLLNQISLLKQNLEIQLSQSQTS 717
Cdd:pfam15921 541 DHLRnvqtecEALKLQMAEKDKvieilrqqiENMTQLVGQHGRTAGAMQVE-KAQLEKEINDRRLELQEFKILKDKKDAK 619
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 718 LQQLQAQFTQerqrLTQELEELEEQHQQRHKSLKEAhvlafqtmeeekEKEQRALENHLQQKHSaELQSLKDAHRESMEG 797
Cdd:pfam15921 620 IRELEARVSD----LELEKVKLVNAGSERLRAVKDI------------KQERDQLLNEVKTSRN-ELNSLSEDYEVLKRN 682
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 798 FRIEMEqELQTLRFELedegKAMLASLRSELNHQHAAAIDLLRHNHHQELAAakMELERSIDISRRQskehmcrITDLQE 877
Cdd:pfam15921 683 FRNKSE-EMETTTNKL----KMQLKSAQSELEQTRNTLKSMEGSDGHAMKVA--MGMQKQITAKRGQ-------IDALQS 748
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 966941256 878 ELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSE----SNQQIRLEE 929
Cdd:pfam15921 749 KIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGElevlRSQERRLKE 804
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
512-708 |
1.95e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 1.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 512 QMELEEQHNKEKLNLEEDKNQLQQELENLK---EVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQT 588
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKkeeKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 589 ELDLTKDSLKETKDA------------LLNVEGELEQER---------QQHEETIAAMKED-EKLKVDKMAHDLEIKWTE 646
Cdd:COG4942 98 ELEAQKEELAELLRAlyrlgrqpplalLLSPEDFLDAVRrlqylkylaPARREQAEELRADlAELAALRAELEAERAELE 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966941256 647 NLRQEcsKLREELRLQHEEDKKSAMSQLLQLKEREKNAARDSWQKKVEDLLNQISLLKQNLE 708
Cdd:COG4942 178 ALLAE--LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
274-485 |
2.04e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 2.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 274 LFTAESLQASKEKEADLRKEFQGqeaiLRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEG 353
Cdd:COG4942 9 LLLALAAAAQADAAAEAEAELEQ----LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 354 EMALLSKHKEVESELAAARERLQQQ---------------------ASDLVLKASHIGMLQATQMTQ----EVTIKDLES 408
Cdd:COG4942 85 LAELEKEIAELRAELEAQKEELAELlralyrlgrqpplalllspedFLDAVRRLQYLKYLAPARREQaeelRADLAELAA 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966941256 409 EKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYE--RELKNLQNRLEEEVTQLNEAHSKT 485
Cdd:COG4942 165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAElqQEAEELEALIARLEAEAAAAAERT 243
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
327-705 |
5.36e-06 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 50.72 E-value: 5.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 327 QKLQTALATAENNVQGLQKQLDDAKEGEMALlskhkevESELAAARERLQ------QQASDLVLKASHIGMLQATQMTQE 400
Cdd:COG3096 295 FGARRQLAEEQYRLVEMARELEELSARESDL-------EQDYQAASDHLNlvqtalRQQEKIERYQEDLEELTERLEEQE 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 401 VTIKDLESEKSRANERLSQLEEERAFLQSK----TQSLDEEQK-----QQILE-LEKKvseakRTQQEYYERELKNLQNR 470
Cdd:COG3096 368 EVVEEAAEQLAEAEARLEAAEEEVDSLKSQladyQQALDVQQTraiqyQQAVQaLEKA-----RALCGLPDLTPENAEDY 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 471 LEEEVTQLNEAHSKTLEElawKHHMAIEAVHSNAIRDKKKL------QMELEEQHNKEKLNLE---EDKNQLQQElenlk 541
Cdd:COG3096 443 LAAFRAKEQQATEEVLEL---EQKLSVADAARRQFEKAYELvckiagEVERSQAWQTARELLRryrSQQALAQRL----- 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 542 EVLEDKLNTANQEIGRLQDLVRKSEQgLGSAEGLIASLQDSQERLQTELDLTKDSLKETKDALLNVEGELEQERQQHEET 621
Cdd:COG3096 515 QQLRAQLAELEQRLRQQQNAERLLEE-FCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRAR 593
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 622 IAAMKedeklkvdkmahDLEIKWTEnLRQECSKLREEL--RLQHEEDKKSAMSQLLQlKEREKNAARDSWQKKVEDLLNQ 699
Cdd:COG3096 594 IKELA------------ARAPAWLA-AQDALERLREQSgeALADSQEVTAAMQQLLE-REREATVERDELAARKQALESQ 659
|
....*.
gi 966941256 700 ISLLKQ 705
Cdd:COG3096 660 IERLSQ 665
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
238-969 |
7.67e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 50.35 E-value: 7.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 238 EELRLEQKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKT--ELQMV 315
Cdd:TIGR00618 179 TQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAqeEQLKK 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 316 QDEAGSLLDKCQKLQTALATAENnvqgLQKQLDDAKEGE-MALLSKH-KEVESELAAARERLQQQASDLVLKASHIGMLQ 393
Cdd:TIGR00618 259 QQLLKQLRARIEELRAQEAVLEE----TQERINRARKAApLAAHIKAvTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHV 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 394 ATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQ-----KQQILELEKKVSEAKRTQQEYYERELKNLQ 468
Cdd:TIGR00618 335 KQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQhihtlQQQKTTLTQKLQSLCKELDILQREQATIDT 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 469 NRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMELEE--QHNKEKLNLEEDKNQLQQELENLKEVLED 546
Cdd:TIGR00618 415 RTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQEsaQSLKEREQQLQTKEQIHLQETRKKAVVLA 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 547 KLntanQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMK 626
Cdd:TIGR00618 495 RL----LELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQ 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 627 EDEKLKVDKMAHDLEIkwtENLRQECSKLREELRLQHEEDKKSAMSQLLQLKEREKNAArdswqkkvedlLNQISLLKQN 706
Cdd:TIGR00618 571 SFSILTQCDNRSKEDI---PNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD-----------LQDVRLHLQQ 636
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 707 LEIQLSQSQTSLQQLQAQFTQERQRLtqeleeleeqhqqrhkslkeaHVLAFQTMEEEKEKEQRALENHLQQKhsaelqs 786
Cdd:TIGR00618 637 CSQELALKLTALHALQLTLTQERVRE---------------------HALSIRVLPKELLASRQLALQKMQSE------- 688
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 787 lkdahRESMEGFRIEMEQELQTLRFELEDEGKamlaslrselNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSK 866
Cdd:TIGR00618 689 -----KEQLTYWKEMLAQCQTLLRELETHIEE----------YDREFNEIENASSSLGSDLAAREDALNQSLKELMHQAR 753
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 867 EHMCRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIRLEEME---EKYLMRESKPED 943
Cdd:TIGR00618 754 TVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDIlnlQCETLVQEEEQF 833
|
730 740
....*....|....*....|....*.
gi 966941256 944 IQMITELKAMLTERDQIIKKLIEDNK 969
Cdd:TIGR00618 834 LSRLEEKSATLGEITHQLLKYEECSK 859
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
46-451 |
1.05e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 49.67 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 46 KMSKKIAQLTKVIYALNTKNDEHESAIQALKDAhEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLEASLEDHIKMK 125
Cdd:TIGR02168 688 ELEEKIAELEKALAELRKELEELEEELEQLRKE-LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 126 QQALTEFEAYKHRVEDMQLCAEAQhvqrIVTMSREVEEIRRKFEEKLRSFGQLQVQFeKDKRLALEDLRTAHRREIQELL 205
Cdd:TIGR02168 767 EERLEEAEEELAEAEAEIEELEAQ----IEQLKEELKALREALDELRAELTLLNEEA-ANLRERLESLERRIAATERRLE 841
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 206 KSQQDHsasvnkgqEKAEElhrmEVESLNKMLEELRLEQKKLIEDyegklnkaqsfyereldtlkrsqlftAESLQASKE 285
Cdd:TIGR02168 842 DLEEQI--------EELSE----DIESLAAEIEELEELIEELESE--------------------------LEALLNERA 883
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 286 KEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLddaKEGEMALLSKHKEVE 365
Cdd:TIGR02168 884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL---SEEYSLTLEEAEALE 960
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 366 SELAAARERLQQQASDLVLKASHIGMLQATqmtqevTIKDLESEKSRANERLSQ---LEEERAFLQSKTQSLDEEQKQQI 442
Cdd:TIGR02168 961 NKIEDDEEEARRRLKRLENKIKELGPVNLA------AIEEYEELKERYDFLTAQkedLTEAKETLEEAIEEIDREARERF 1034
|
....*....
gi 966941256 443 LELEKKVSE 451
Cdd:TIGR02168 1035 KDTFDQVNE 1043
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
108-964 |
1.12e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.68 E-value: 1.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 108 RRKIQVLEASLEDHIKMKQQALTEFEAYKHRVEDMQLCaeaqhvqrIVTMSREVEEIRRKFEEKLRsFGQLQVQFEKDKR 187
Cdd:TIGR02169 155 RRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLI--------IDEKRQQLERLRREREKAER-YQALLKEKREYEG 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 188 LALEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELhRMEVESLNKMLEELRLEQKKLIEDYEGKLNKAQSFYERELD 267
Cdd:TIGR02169 226 YELLKEKEALERQKEAIERQLASLEEELEKLTEEISEL-EKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 268 TLKRSQLFTAESLQaskekeadlrkEFQGQEAILRKTIGKLKTELQmvqdeagslldkcqKLQTALATAENNVQGLQKQL 347
Cdd:TIGR02169 305 SLERSIAEKERELE-----------DAEERLAKLEAEIDKLLAEIE--------------ELEREIEEERKRRDKLTEEY 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 348 DDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFL 427
Cdd:TIGR02169 360 AELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINEL 439
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 428 QSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYEreLKNLQNRLEEEVTQLN------EAHSKTLEELAWKHHMA----- 496
Cdd:TIGR02169 440 EEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD--LKEEYDRVEKELSKLQrelaeaEAQARASEERVRGGRAVeevlk 517
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 497 --IEAVH---SNAIRDKKKLQMELE-EQHNKEKLNLEEDKNQLQQELENLKEVledklntanqEIGRLQDL------VRK 564
Cdd:TIGR02169 518 asIQGVHgtvAQLGSVGERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRR----------KAGRATFLplnkmrDER 587
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 565 SEQGLGSAEGLIA---SLQDSQERLQTEL------DLTKDSLKETKDALLNV-----EGELEQER------QQHEETIAA 624
Cdd:TIGR02169 588 RDLSILSEDGVIGfavDLVEFDPKYEPAFkyvfgdTLVVEDIEAARRLMGKYrmvtlEGELFEKSgamtggSRAPRGGIL 667
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 625 MKEDEKLKVDKMAHDLEikwteNLRQECSKLREELRLQheedkKSAMSQLLQLKEREknaardswQKKVEDLLNQISLLK 704
Cdd:TIGR02169 668 FSRSEPAELQRLRERLE-----GLKRELSSLQSELRRI-----ENRLDELSQELSDA--------SRKIGEIEKEIEQLE 729
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 705 QNLEIQLSQSQTSlqqlqaqftQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAEL 784
Cdd:TIGR02169 730 QEEEKLKERLEEL---------EEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAEL 800
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 785 QSLKDAHREsMEGFRIEMEQELQ--TLRFELEDEGKAMLASLRSELNHQHAAaidllRHNHHQELAAAKMELERSIDISR 862
Cdd:TIGR02169 801 SKLEEEVSR-IEARLREIEQKLNrlTLEKEYLEKEIQELQEQRIDLKEQIKS-----IEKEIENLNGKKEELEEELEELE 874
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 863 RQSKEHMCRITDLQEELRHREHHISELDKEVQHLHENISALTKELEfkgkeiLRIRSESNQQIRLEEMEEKYLMRESKPE 942
Cdd:TIGR02169 875 AALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS------ELKAKLEALEEELSEIEDPKGEDEEIPE 948
|
890 900
....*....|....*....|..
gi 966941256 943 DIQMITELKAMLTERDQIIKKL 964
Cdd:TIGR02169 949 EELSLEDVQAELQRVEEEIRAL 970
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
324-567 |
1.64e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.61 E-value: 1.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 324 DKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQqasdlvlkashigmLQATQMTQEVTI 403
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA--------------LEQELAALEAEL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 404 KDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQeYYERELKNLQNRLEEevtqlneaHS 483
Cdd:COG4942 86 AELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQ-YLKYLAPARREQAEE--------LR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 484 KTLEELAwkhhmAIEAVHSNAIRDKKKLQMELEEQHnKEKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGRLQDLVR 563
Cdd:COG4942 157 ADLAELA-----ALRAELEAERAELEALLAELEEER-AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
|
....
gi 966941256 564 KSEQ 567
Cdd:COG4942 231 RLEA 234
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
227-480 |
2.12e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 48.75 E-value: 2.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 227 RMEVESLNKMlEELRLEQKKLIEDyegkLNKAQSF------YERELDTLKRsQLFTA-ESLQASKEKEADLRKEfqgQEA 299
Cdd:PRK11281 42 QAQLDALNKQ-KLLEAEDKLVQQD----LEQTLALldkidrQKEETEQLKQ-QLAQApAKLRQAQAELEALKDD---NDE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 300 ILRKTIGKLK-TELQMVQDEagsLLDKCQKLQTALATAENNVQGLQKQLDDAkegemallskhkevESELAAARERLQQ- 377
Cdd:PRK11281 113 ETRETLSTLSlRQLESRLAQ---TLDQLQNAQNDLAEYNSQLVSLQTQPERA--------------QAALYANSQRLQQi 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 378 -------QASDLVLKASHIGMLQATQ-------------MTQEVTIKDL-ESEKSRANERLSQLEEERAFLQ----SKTQ 432
Cdd:PRK11281 176 rnllkggKVGGKALRPSQRVLLQAEQallnaqndlqrksLEGNTQLQDLlQKQRDYLTARIQRLEHQLQLLQeainSKRL 255
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 966941256 433 SLDEEQKQQILELEKKvseAKRTQQEYYEREL-KNLQ--NRLEEEVTQLNE 480
Cdd:PRK11281 256 TLSEKTVQEAQSQDEA---ARIQANPLVAQELeINLQlsQRLLKATEKLNT 303
|
|
| Nup88 |
pfam10168 |
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ... |
472-657 |
2.57e-05 |
|
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.
Pssm-ID: 462975 [Multi-domain] Cd Length: 713 Bit Score: 48.50 E-value: 2.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 472 EEEVTQLNEAHSKTLEELAWKHHMAIEAV--HSNAIRDKKKLQmeLEEQHNkeklnLEEDKNQLQQELENLKEVLEDKLN 549
Cdd:pfam10168 531 QECLQLLSRATQVFREEYLKKHDLAREEIqkRVKLLKLQKEQQ--LQELQS-----LEEERKSLSERAEKLAEKYEEIKD 603
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 550 taNQEigrlqDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKETKDALLNVEGELEQERQQheetIAAMKEDE 629
Cdd:pfam10168 604 --KQE-----KLMRRCKKVLQRLNSQLPVLSDAEREMKKELETINEQLKHLANAIKQAKKKMNYQRYQ----IAKSQSIR 672
|
170 180
....*....|....*....|....*...
gi 966941256 630 KLKVDKMAHDLEIKWTENLRQECSKLRE 657
Cdd:pfam10168 673 KKSSLSLSEKQRKTIKEILKQLGSEIDE 700
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
359-591 |
3.53e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.45 E-value: 3.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 359 SKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQ 438
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 439 KQQILELEKKVSEAKRTQQEYYERELKNLQN-----RLEEEVTQLNEAHSKTLEELAwkhhmaieavhsnaiRDKKKLQm 513
Cdd:COG4942 100 EAQKEELAELLRALYRLGRQPPLALLLSPEDfldavRRLQYLKYLAPARREQAEELR---------------ADLAELA- 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966941256 514 ELEEQHNKEKLNLEEDKNQLQQELENLKEVLEDKlntanqeigrlQDLVRKSEQGLGSAEGLIASLQDSQERLQTELD 591
Cdd:COG4942 164 ALRAELEAERAELEALLAELEEERAALEALKAER-----------QKLLARLEKELAELAAELAELQQEAEELEALIA 230
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
403-903 |
8.52e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 46.96 E-value: 8.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 403 IKDLESEKSRANERLSQLEEERAFLQSKTQSLdEEQKQQILELEKKVSEAKRTQQEYYEReLKNLQNRLEEEVTQLNEAH 482
Cdd:PRK02224 222 IERYEEQREQARETRDEADEVLEEHEERREEL-ETLEAEIEDLRETIAETEREREELAEE-VRDLRERLEELEEERDDLL 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 483 SKT-LEELAWKhhmAIEAVHSNAIRDKKKLQMELEEQ------HNKEKLNLEEDKNQLQQELENLKE---VLEDKLNTAN 552
Cdd:PRK02224 300 AEAgLDDADAE---AVEARREELEDRDEELRDRLEECrvaaqaHNEEAESLREDADDLEERAEELREeaaELESELEEAR 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 553 QEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLtkdsLKETKDALLNVEGELEQERQQHEETIAamkEDEKL- 631
Cdd:PRK02224 377 EAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEE----LREERDELREREAELEATLRTARERVE---EAEALl 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 632 ----------KVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKsAMSQLLQLKEREKnaardswqkKVEDLLNQIS 701
Cdd:PRK02224 450 eagkcpecgqPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEE-RLERAEDLVEAED---------RIERLEERRE 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 702 LLKQNLEIQLSQSQTSlqqlqaqfTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENhlqqkhS 781
Cdd:PRK02224 520 DLEELIAERRETIEEK--------RERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAEL------K 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 782 AELQSLKDAhrESMEGFRIEMEQELQTLR------FELEDEGKAMLASLR---SELNHQH-AAAIDLLRHNHhQELAAAK 851
Cdd:PRK02224 586 ERIESLERI--RTLLAAIADAEDEIERLRekrealAELNDERRERLAEKRerkRELEAEFdEARIEEAREDK-ERAEEYL 662
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 966941256 852 MELERSIDISRRQSKEHMCRITDLQ------EELRHREHHISELDKEVQHLHENISAL 903
Cdd:PRK02224 663 EQVEEKLDELREERDDLQAEIGAVEneleelEELRERREALENRVEALEALYDEAEEL 720
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
213-454 |
1.14e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 213 ASVNKGQEKAEELHRM--EVESLNKMLEELRLEQKKLIEDYEgKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADL 290
Cdd:COG4942 17 AQADAAAEAEAELEQLqqEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 291 RKEFQGQEAILRKTIGKLkteLQMVQDEAGSLLDKCQKLQTALATAEnnvqgLQKQLDDAKEGEMALLSKHKEvesELAA 370
Cdd:COG4942 96 RAELEAQKEELAELLRAL---YRLGRQPPLALLLSPEDFLDAVRRLQ-----YLKYLAPARREQAEELRADLA---ELAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 371 ARERLQQQASDLvlkashigmlQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQ---QILELEK 447
Cdd:COG4942 165 LRAELEAERAEL----------EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEleaLIARLEA 234
|
....*..
gi 966941256 448 KVSEAKR 454
Cdd:COG4942 235 EAAAAAE 241
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
190-796 |
1.25e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 46.26 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 190 LEDLRTAHRREIQELLKSQQDHSasvnkgqEKAEELHRMEVESLNKMLEELRLEQKKL---IEDYEGKLNKAQSFYEREL 266
Cdd:pfam15921 247 LEALKSESQNKIELLLQQHQDRI-------EQLISEHEVEITGLTEKASSARSQANSIqsqLEIIQEQARNQNSMYMRQL 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 267 DTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAEnnvqglqKQ 346
Cdd:pfam15921 320 SDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKRE-------KE 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 347 LDDAKEGEMALLSKhkevESELAAARERLQQQASDLVLKASHIgmlqatqmtqEVTIKDLESEKSranerlSQLEEERAF 426
Cdd:pfam15921 393 LSLEKEQNKRLWDR----DTGNSITIDHLRRELDDRNMEVQRL----------EALLKAMKSECQ------GQMERQMAA 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 427 LQSKTQSLDE-----EQKQQILELEKKVSE---AKRTQQEYYERELKNLQNRLEEEvtqlneahsktleelawkhHMAIE 498
Cdd:pfam15921 453 IQGKNESLEKvssltAQLESTKEMLRKVVEeltAKKMTLESSERTVSDLTASLQEK-------------------ERAIE 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 499 AVHSNAIRDKKKLQMELEE-QHNKeklNLEEDKNQLQQELENLKEVLEDK---LNTANQEIGRLQDLVRKSEQGLGSAEG 574
Cdd:pfam15921 514 ATNAEITKLRSRVDLKLQElQHLK---NEGDHLRNVQTECEALKLQMAEKdkvIEILRQQIENMTQLVGQHGRTAGAMQV 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 575 LIASLQDSQERLQTELDLTKdSLKETKDALL--------NVEGELEQERQQHEETIAAMKeDEKLKVDKMAHDLEIKWTE 646
Cdd:pfam15921 591 EKAQLEKEINDRRLELQEFK-ILKDKKDAKIrelearvsDLELEKVKLVNAGSERLRAVK-DIKQERDQLLNEVKTSRNE 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 647 --NLRQECSKLREELRLQHEEDKKSAMSQLLQLKereknaardSWQKKVEDLLNQIsllkQNLEIQLSQSQTSLQQLQAQ 724
Cdd:pfam15921 669 lnSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLK---------SAQSELEQTRNTL----KSMEGSDGHAMKVAMGMQKQ 735
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966941256 725 FTQERQRLTQELEELEEQHQQRHKSLKEAHVLafqtmEEEKEKEQRALENHLQQKH--SAELQSLKDAHRESME 796
Cdd:pfam15921 736 ITAKRGQIDALQSKIQFLEEAMTNANKEKHFL-----KEEKNKLSQELSTVATEKNkmAGELEVLRSQERRLKE 804
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
74-603 |
1.36e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.12 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 74 ALKDAHEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLEASLEDHIKMKQQALTEFE-------AYKHRVEDMQLCA 146
Cdd:TIGR00618 333 HVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTqklqslcKELDILQREQATI 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 147 EAQHVQRIV-----TMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLRTAHRREIQELLKSQQDHsasvnkgqEK 221
Cdd:TIGR00618 413 DTRTSAFRDlqgqlAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIH--------LQ 484
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 222 AEELHRMEVESLNKMLEELRLEQKKLIEDYEgklnKAQSFYERELDTLKRSQLFTAESLQASKEKEADlrkefqGQEAIL 301
Cdd:TIGR00618 485 ETRKKAVVLARLLELQEEPCPLCGSCIHPNP----ARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVY------HQLTSE 554
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 302 RKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEGE--MALLSKHKEVESELAAARERL---- 375
Cdd:TIGR00618 555 RKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEdmLACEQHALLRKLQPEQDLQDVrlhl 634
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 376 QQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRAnERLSQLEEERAFLQSKTQSLDE-----EQKQQILELEKKVS 450
Cdd:TIGR00618 635 QQCSQELALKLTALHALQLTLTQERVREHALSIRVLPK-ELLASRQLALQKMQSEKEQLTYwkemlAQCQTLLRELETHI 713
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 451 EAKRTQQEYYERELKNLQNRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMELEEQHNKEKLN----- 525
Cdd:TIGR00618 714 EEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQffnrl 793
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 526 -------LEEDKNQLQQELENLKEVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLK 598
Cdd:TIGR00618 794 reedthlLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQ 873
|
....*
gi 966941256 599 ETKDA 603
Cdd:TIGR00618 874 LSDKL 878
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
81-506 |
1.55e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 81 EEIQQILAETREKILQYKSKVTEELDLRRKIQVLEASLEDHIKMKQQALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSRE 160
Cdd:COG4717 74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 161 VEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELhRMEVESLNKMLEEl 240
Cdd:COG4717 154 RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA-QEELEELEEELEQ- 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 241 rLEQKKLIEDYEGKLNKAQSFYerELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAG 320
Cdd:COG4717 232 -LENELEAAALEERLKEARLLL--LIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQ 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 321 SLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKAshigMLQATQMTQE 400
Cdd:COG4717 309 ALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAA----LLAEAGVEDE 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 401 VTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYERELKNLQNRLEEEVTQLNE 480
Cdd:COG4717 385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQ 464
|
410 420
....*....|....*....|....*..
gi 966941256 481 A-HSKTLEELAWKHHMAIEAVHSNAIR 506
Cdd:COG4717 465 LeEDGELAELLQELEELKAELRELAEE 491
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
77-650 |
2.25e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 45.55 E-value: 2.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 77 DAHEEEIQQILAETREKILQYKSKVTEELDlrrKIQVLEASLEDHIKMKQQALTEFEAYKHRVEDMQLCAEAQHVQRivt 156
Cdd:pfam01576 214 EGESTDLQEQIAELQAQIAELRAQLAKKEE---ELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAAR--- 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 157 msREVEEIRRKFEEKLRSFgQLQVQFEKDKRLALEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKM 236
Cdd:pfam01576 288 --NKAEKQRRDLGEELEAL-KTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQ 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 237 LEELRlEQKKLIEDYEGKLNKAQSFYERELDTLKRSQlftAESLQASKEKEADLRK------EFQGQEAILRKTIGKLKT 310
Cdd:pfam01576 365 LEQAK-RNKANLEKAKQALESENAELQAELRTLQQAK---QDSEHKRKKLEGQLQElqarlsESERQRAELAEKLSKLQS 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 311 ELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIG 390
Cdd:pfam01576 441 ELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLS 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 391 MLQAtqmtqevTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYyeRELKNLQNR 470
Cdd:pfam01576 521 TLQA-------QLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQEL--DDLLVDLDH 591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 471 LEEEVTQLNEAHSKTLEELAWKhhmaiEAVHSNAIRDKKKLQMELEEQHNKEKlnleedknQLQQELENLKEVLEDKLNT 550
Cdd:pfam01576 592 QRQLVSNLEKKQKKFDQMLAEE-----KAISARYAEERDRAEAEAREKETRAL--------SLARALEEALEAKEELERT 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 551 ANQEIGRLQDLVRKSEQGLGSAEGLIAS---LQDSQERLQTELDLTKDSLKETKDALLNVEGELEQERQQHEETIAA--- 624
Cdd:pfam01576 659 NKQLRAEMEDLVSSKDDVGKNVHELERSkraLEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQArde 738
|
570 580
....*....|....*....|....*.
gi 966941256 625 MKEDEKLKVDKMAHDLEIKWTENLRQ 650
Cdd:pfam01576 739 QGEEKRRQLVKQVRELEAELEDERKQ 764
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
287-964 |
2.41e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 45.21 E-value: 2.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 287 EADLRKEFQGQEAILRKTIGKLKTELQMVQDEagslldkcqkLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEves 366
Cdd:pfam12128 274 IASRQEERQETSAELNQLLRTLDDQWKEKRDE----------LNGELSAADAAVAKDRSELEALEDQHGAFLDADIE--- 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 367 ELAAARERLQQQASDL-VLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILEL 445
Cdd:pfam12128 341 TAAADQEQLPSWQSELeNLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQAL 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 446 EKKVSEAKRTQQEYYERELKNLQNRLEEEVTQLNEAhSKTLEELawkhhMAIEAVHSNAIRDKKKLqmeleEQHNKEKLN 525
Cdd:pfam12128 421 ESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQA-TATPELL-----LQLENFDERIERAREEQ-----EAANAEVER 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 526 LEEDKNQLQQELENLKEVLEDKLNTANQEIGRLQDLvrkSEQGLGSAEGLIaslqdsqERLQTELDLTKDSLKETKDALL 605
Cdd:pfam12128 490 LQSELRQARKRRDQASEALRQASRRLEERQSALDEL---ELQLFPQAGTLL-------HFLRKEAPDWEQSIGKVISPEL 559
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 606 NVEGELeqerqqHEETIAAMKEDE------KLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEdKKSAMSQLLQLke 679
Cdd:pfam12128 560 LHRTDL------DPEVWDGSVGGElnlygvKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREK-QAAAEEQLVQA-- 630
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 680 rekNAARDSWQKKVEDLLnqisllkqnleiqlsqsqtslqqlqAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAfQ 759
Cdd:pfam12128 631 ---NGELEKASREETFAR-------------------------TALKNARLDLRRLFDEKQSEKDKKNKALAERKDSA-N 681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 760 TMEEEKEKEQRALENhlqqKHSAELQSLKDAHRESmegfRIEMEQELQtlrfELEDEGKAMLASLRSEL---NHQHAAAI 836
Cdd:pfam12128 682 ERLNSLEAQLKQLDK----KHQAWLEEQKEQKREA----RTEKQAYWQ----VVEGALDAQLALLKAAIaarRSGAKAEL 749
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 837 DLLRHNHHQELAAAKMELERSIDISrRQSKEHMCRItdlqEELRHREHHISELDKEVQH--LHENiSALTKELEFKGKEI 914
Cdd:pfam12128 750 KALETWYKRDLASLGVDPDVIAKLK-REIRTLERKI----ERIAVRRQEVLRYFDWYQEtwLQRR-PRLATQLSNIERAI 823
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|
gi 966941256 915 LRIRSESNQQIRLEEMEEKYLMRESKPEDIQMItELKAMLTERDQIIKKL 964
Cdd:pfam12128 824 SELQQQLARLIADTKLRRAKLEMERKASEKQQV-RLSENLRGLRCEMSKL 872
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
194-984 |
2.61e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.35 E-value: 2.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 194 RTAHRREIQELLKSQQ---DHSASVNKGQE-------KAEELHRME---VESLNKMLEELRLEQKKLIEDYEGKLNKAQS 260
Cdd:pfam02463 114 KNVTKKEVAELLESQGispEAYNFLVQGGKieiiammKPERRLEIEeeaAGSRLKRKKKEALKKLIEETENLAELIIDLE 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 261 FYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNV 340
Cdd:pfam02463 194 ELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKE 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 341 QGLQKQLDDAKEGEMALLSKhKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQL 420
Cdd:pfam02463 274 NKEEEKEKKLQEEELKLLAK-EEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKRE 352
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 421 EEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYERELKNLQNRLEEEVTQLNEAHSKTLEELAWKHHMAIEAV 500
Cdd:pfam02463 353 AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEIL 432
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 501 HSNAIRDKKKLQMELEEQHNKEKLNLEEDKNQLQ-QELENLKEVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASL 579
Cdd:pfam02463 433 EEEEESIELKQGKLTEEKEELEKQELKLLKDELElKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVL 512
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 580 QDSQERLQTELDLTKDSLK---ETKDALLNVEGELEQERQQHEETIAAMKEDEKLKVDKMAHDLEIKWTENLRQECSKLR 656
Cdd:pfam02463 513 LALIKDGVGGRIISAHGRLgdlGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLK 592
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 657 EELRLQHEEDKKSAMSQLLQLKEREKNAARDSWQK----KVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRL 732
Cdd:pfam02463 593 SIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGilkdTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELT 672
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 733 TQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFE 812
Cdd:pfam02463 673 KELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEE 752
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 813 LEDEGKAMLA-SLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHMcRITDLQEELRHREHHISELDK 891
Cdd:pfam02463 753 EKSRLKKEEKeEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEEL-KEEAELLEEEQLLIEQEEKIK 831
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 892 EVQHLHENISALTKELEFKGKEILRIRSESNQQIRLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFY 971
Cdd:pfam02463 832 EEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNL 911
|
810
....*....|...
gi 966941256 972 QLELVNRETNFNK 984
Cdd:pfam02463 912 LEEKENEIEERIK 924
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
354-566 |
3.11e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 44.73 E-value: 3.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 354 EMALLSKHKEVESELAAARE-RLQQQASDLVLKASHIGMLQ---ATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQS 429
Cdd:pfam17380 384 QMERQQKNERVRQELEAARKvKILEEERQRKIQQQKVEMEQiraEQEEARQREVRRLEEERAREMERVRLEEQERQQQVE 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 430 KTQSLDEEQKQQILELEKKvseaKRTQQEYYERELKNLQNRLEEEVTQLNEAHSKtleelawkhhmaieavhsnairdKK 509
Cdd:pfam17380 464 RLRQQEEERKRKKLELEKE----KRDRKRAEEQRRKILEKELEERKQAMIEEERK-----------------------RK 516
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 966941256 510 KLQMELEEQHN----KEKLNLEEDKNQLQQELENLKEVlEDKLNTANQEIGRLQDLVRKSE 566
Cdd:pfam17380 517 LLEKEMEERQKaiyeEERRREAEEERRKQQEMEERRRI-QEQMRKATEERSRLEAMERERE 576
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
305-708 |
3.80e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 44.43 E-value: 3.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 305 IGKLKTELQMVQDEAgslldkcQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVL 384
Cdd:pfam10174 291 IDQLKQELSKKESEL-------LALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNK 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 385 KASHIGMLQATQMTQEVTIKDLEseksranERLSQLEEERAFLQSKTQSLDEeqkqQILELEKKVSEAKRTQQEyyerel 464
Cdd:pfam10174 364 KTKQLQDLTEEKSTLAGEIRDLK-------DMLDVKERKINVLQKKIENLQE----QLRDKDKQLAGLKERVKS------ 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 465 knlqnrLEEEVTQLNEAHSkTLEELAWKHHMAIEAVHSNAIRDKKKLQMELEeQHNKEKLNLEEDKNQLQQELENLKEVL 544
Cdd:pfam10174 427 ------LQTDSSNTDTALT-TLEEALSEKERIIERLKEQREREDRERLEELE-SLKKENKDLKEKVSALQPELTEKESSL 498
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 545 EDKLNTANQeigrLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKE--TKDALLNVEGELEQERQQHEET- 621
Cdd:pfam10174 499 IDLKEHASS----LASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAvrTNPEINDRIRLLEQEVARYKEEs 574
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 622 ------------IAAMKEDEKLKVDKMAHDLEiKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKEREKNAARDSW 689
Cdd:pfam10174 575 gkaqaeverllgILREVENEKNDKDKKIAELE-SLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQ 653
|
410
....*....|....*....
gi 966941256 690 QKKVEDLLNQISLLKQNLE 708
Cdd:pfam10174 654 QLQLEELMGALEKTRQELD 672
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
98-619 |
3.81e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 44.51 E-value: 3.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 98 KSKVTEELDLRRKIQVLEASLEDHIKMKQQALTEFEAykhrVEDmqlcaEAQHVQRIVTMSREVEEIRRKFEEKLRsfgq 177
Cdd:PRK01156 193 KSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNN----AMD-----DYNNLKSALNELSSLEDMKNRYESEIK---- 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 178 lqvqfEKDKRLALEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLEQKKLiEDYEGKLNK 257
Cdd:PRK01156 260 -----TAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKY-HAIIKKLSV 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 258 AQSFYERELDTLKRsqlftaeslqasKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAE 337
Cdd:PRK01156 334 LQKDYNDYIKKKSR------------YDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQE 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 338 NNVQGLQKQLDDAKegemallSKHKEVESELAAARERLQQQASDLVLKASHIGMLQAtQMTQEVTIKDLESEKSRA---- 413
Cdd:PRK01156 402 IDPDAIKKELNEIN-------VKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNG-QSVCPVCGTTLGEEKSNHiinh 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 414 -NERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYY----------------ERELKNLQNRLEEEVT 476
Cdd:PRK01156 474 yNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYnkiesaradledikikINELKDKHDKYEEIKN 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 477 QLNEAHSKTLEE--------LAWKHHMAIEAVHSNAIRDKKKLQmELEEQHNKEKLNLEEDKNQLQQ---ELENLKEVLE 545
Cdd:PRK01156 554 RYKSLKLEDLDSkrtswlnaLAVISLIDIETNRSRSNEIKKQLN-DLESRLQEIEIGFPDDKSYIDKsirEIENEANNLN 632
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966941256 546 DKLNTAnQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKETKDALLNVEGELEQERQQHE 619
Cdd:PRK01156 633 NKYNEI-QENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIE 705
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
260-985 |
3.98e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 44.75 E-value: 3.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 260 SFYERELDTLKRSQlfTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENN 339
Cdd:PTZ00121 1075 SYKDFDFDAKEDNR--ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAK 1152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 340 VQGLQKQLDDAKEGEmalLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVtikdleseksRANERLSQ 419
Cdd:PTZ00121 1153 RVEIARKAEDARKAE---EARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEE----------RKAEEARK 1219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 420 LEEERAFlqsktqsldeEQKQQILELEKKVSEAKRTQQEyyerelknlqnRLEEEVTQLNEAHSKTL--EELAWKHHMAI 497
Cdd:PTZ00121 1220 AEDAKKA----------EAVKKAEEAKKDAEEAKKAEEE-----------RNNEEIRKFEEARMAHFarRQAAIKAEEAR 1278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 498 EAVHSNAIRDKKKLQmELEEQHNKEKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIA 577
Cdd:PTZ00121 1279 KADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD 1357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 578 SLQDSQERLQTElDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEDEKLK----VDKMAHDLEIKWTENLRQECS 653
Cdd:PTZ00121 1358 EAEAAEEKAEAA-EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKkaaaAKKKADEAKKKAEEKKKADEA 1436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 654 KLREELRLQHEEDKKSA----MSQLLQLKEREKNAArDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQER 729
Cdd:PTZ00121 1437 KKKAEEAKKADEAKKKAeeakKAEEAKKKAEEAKKA-DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA 1515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 730 QRLTQELEELEEQHQQRHKSLKEAHvlafQTMEEEKEKEQRALEN--HLQQKHSAElQSLKDAHRESMEGFRIEMEQELQ 807
Cdd:PTZ00121 1516 KKAEEAKKADEAKKAEEAKKADEAK----KAEEKKKADELKKAEElkKAEEKKKAE-EAKKAEEDKNMALRKAEEAKKAE 1590
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 808 TLRFELEDEGKAMLASLRSELNHQHAAAidllrhNHHQELAAAKMELERSIDISRRQSKEHMCRITDLQEELRHREHHIS 887
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKAEEA------KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA 1664
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 888 ELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIRLEEMEEKYLMRESKPEDIQMITELKAMLTERdqiIKKLIED 967
Cdd:PTZ00121 1665 EEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEE---AKKEAEE 1741
|
730
....*....|....*...
gi 966941256 968 NKFYQLELVNRETNFNKV 985
Cdd:PTZ00121 1742 DKKKAEEAKKDEEEKKKI 1759
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
112-687 |
4.56e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 4.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 112 QVLEA-SLEDHIKMKQQALTEFEAYKHRVEDMQlcAEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLAL 190
Cdd:COG4913 216 YMLEEpDTFEAADALVEHFDDLERAHEALEDAR--EQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 191 EDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLEQKKLiedyegklnkaqsfyERELDTLK 270
Cdd:COG4913 294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERL---------------ERELEERE 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 271 RSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQldda 350
Cdd:COG4913 359 RRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR---- 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 351 kegemallskHKEVESELAAARERLqqqASDLVLKASH---IGMLqatqmtqeVTIKDLES------EKSRANERLSQLE 421
Cdd:COG4913 435 ----------KSNIPARLLALRDAL---AEALGLDEAElpfVGEL--------IEVRPEEErwrgaiERVLGGFALTLLV 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 422 EERAFLQ--SKTQSLDEEQKQQILELEKKVSEAKRTQQE----YYERELKN--LQNRLEEEVTQLNEAHS-KTLEELAwK 492
Cdd:COG4913 494 PPEHYAAalRWVNRLHLRGRLVYERVRTGLPDPERPRLDpdslAGKLDFKPhpFRAWLEAELGRRFDYVCvDSPEELR-R 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 493 HHMAIEA---VHSNAIRDKKKLQMELEEQH-----NKEKLN-LEEDKNQLQQELENLKEV---LEDKLNTANQEIGRLQD 560
Cdd:COG4913 573 HPRAITRagqVKGNGTRHEKDDRRRIRSRYvlgfdNRAKLAaLEAELAELEEELAEAEERleaLEAELDALQERREALQR 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 561 L--VRKSEQGLGSAEGLIASLQDSQERLQ------TELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMkEDEKLK 632
Cdd:COG4913 653 LaeYSWDEIDVASAEREIAELEAELERLDassddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA-EEELDE 731
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 966941256 633 VDKMAHDLEIKWTENLRQECSKLREELRL-QHEEDKKSAMSQLLQLKEREKNAARD 687
Cdd:COG4913 732 LQDRLEAAEDLARLELRALLEERFAAALGdAVERELRENLEERIDALRARLNRAEE 787
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
67-656 |
5.52e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.06 E-value: 5.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 67 EHESAIQALkdahEEEIQQILAETREKILQYKSKVTEELD-LRRKIQVLEASledhIKMKQQALTEFEAYKHRVEDMQLC 145
Cdd:pfam12128 269 SDETLIASR----QEERQETSAELNQLLRTLDDQWKEKRDeLNGELSAADAA----VAKDRSELEALEDQHGAFLDADIE 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 146 AEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDL---------RTAHRREIQELLKSQ-----QDH 211
Cdd:pfam12128 341 TAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNnrdiagikdKLAKIREARDRQLAVaeddlQAL 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 212 SASVNKGQEKAEELHRMEVESLNKMLEELRLEQKKLIEDYEGKLNKAQS--------------FYERELDTLKRSQLFTA 277
Cdd:pfam12128 421 ESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFderierareeqeaaNAEVERLQSELRQARKR 500
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 278 ESLQASKEKEADLRKEFQGQEAILRKTIGK---------LKTELQMVQDEAGSLLDKCQKLQTAL--------ATAENNV 340
Cdd:pfam12128 501 RDQASEALRQASRRLEERQSALDELELQLFpqagtllhfLRKEAPDWEQSIGKVISPELLHRTDLdpevwdgsVGGELNL 580
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 341 QGLQKQLD-----DAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQAT-------------------- 395
Cdd:pfam12128 581 YGVKLDLKridvpEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREetfartalknarldlrrlfd 660
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 396 --QMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTqqeyYERELKNLQNRLEE 473
Cdd:pfam12128 661 ekQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQV----VEGALDAQLALLKA 736
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 474 EVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDkKKLQMELEEQHNKEKlNLEEDKNQ-------LQQELENLKEVLED 546
Cdd:pfam12128 737 AIAARRSGAKAELKALETWYKRDLASLGVDPDVI-AKLKREIRTLERKIE-RIAVRRQEvlryfdwYQETWLQRRPRLAT 814
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 547 KLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELD--LTKDSLKETKDALLNVEGELEQERQQHEETIAA 624
Cdd:pfam12128 815 QLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSenLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQ 894
|
650 660 670
....*....|....*....|....*....|..
gi 966941256 625 MkEDEKLKVDKMAHDLEiKWTENLRQECSKLR 656
Cdd:pfam12128 895 L-EDLKLKRDYLSESVK-KYVEHFKNVIADHS 924
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
417-595 |
7.12e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 7.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 417 LSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYY---------ERELKNLQNRLEE------EVTQLNEA 481
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAelqeeleelEEELEELEAELEElreeleKLEKLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 482 HSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMELEEQHNKEKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGRLQDL 561
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207
|
170 180 190
....*....|....*....|....*....|....
gi 966941256 562 VRKSEQGLGSAEGLIASLQDSQERLQTELDLTKD 595
Cdd:COG4717 208 LAELEEELEEAQEELEELEEELEQLENELEAAAL 241
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
243-461 |
1.03e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.89 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 243 EQKKLIEDYEGKLNKAQSfyerELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQdEAGSL 322
Cdd:COG3883 27 ELQAELEAAQAELDALQA----ELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY-RSGGS 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 323 LDKCQKLQTA--LATAENNVQGLQKQLDDAKEgemaLLSKHKEVESELAAARERLQQQASDLVLK----ASHIGMLQATQ 396
Cdd:COG3883 102 VSYLDVLLGSesFSDFLDRLSALSKIADADAD----LLEELKADKAELEAKKAELEAKLAELEALkaelEAAKAELEAQQ 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966941256 397 MTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYE 461
Cdd:COG3883 178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 242
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
407-627 |
1.75e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.12 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 407 ESEKSRANERLSQLEEERAFLQSKTQSLD---EEQKQQILELEKKVSEAKrTQQEYYERELKNLQNRLEEEVTQLNEA-- 481
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQaelEELNEEYNELQAELEALQ-AEIDKLQAEIAEAEAEIEERREELGERar 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 482 ----------------HSKTLEELAWKhhmaIEAVHSNAIRDKKKLqmeleeqhnkeklnleEDKNQLQQELENLKEVLE 545
Cdd:COG3883 94 alyrsggsvsyldvllGSESFSDFLDR----LSALSKIADADADLL----------------EELKADKAELEAKKAELE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 546 DKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAM 625
Cdd:COG3883 154 AKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAA 233
|
..
gi 966941256 626 KE 627
Cdd:COG3883 234 AA 235
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
509-637 |
2.59e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.69 E-value: 2.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 509 KKLQMELEEQHNKEKLNLEEDKNQLQQElenlKEVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQT 588
Cdd:PRK12704 67 HKLRNEFEKELRERRNELQKLEKRLLQK----EENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQ 142
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 966941256 589 ELD----LTKDslkETKDALL-NVEGELEQERQqheETIAAMKEDEKLKVDKMA 637
Cdd:PRK12704 143 ELErisgLTAE---EAKEILLeKVEEEARHEAA---VLIKEIEEEAKEEADKKA 190
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
301-629 |
2.60e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.93 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 301 LRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQAS 380
Cdd:TIGR04523 340 LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQ 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 381 DLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYy 460
Cdd:TIGR04523 420 EKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKEL- 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 461 eRELKNLQNRLEEEVTQLNEAHSKTLEELawKHHMAIEAVHSNAIRDKKKLQMELEEqhNKEKLNLEEDKNQLQQELENL 540
Cdd:TIGR04523 499 -KKLNEEKKELEEKVKDLTKKISSLKEKI--EKLESEKKEKESKISDLEDELNKDDF--ELKKENLEKEIDEKNKEIEEL 573
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 541 KEvlEDKLNTANQEigRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTK---DSLKETKDALLNVEGELEQERQQ 617
Cdd:TIGR04523 574 KQ--TQKSLKKKQE--EKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKkenEKLSSIIKNIKSKKNKLKQEVKQ 649
|
330
....*....|..
gi 966941256 618 HEETIAAMKEDE 629
Cdd:TIGR04523 650 IKETIKEIRNKW 661
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
305-620 |
2.90e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.43 E-value: 2.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 305 IGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKegemallSKHKEVESELAAARERLQQQASDLVL 384
Cdd:COG4372 26 IAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQAR-------SELEQLEEELEELNEQLQAAQAELAQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 385 KASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYEREL 464
Cdd:COG4372 99 AQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSE 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 465 KNLQNRLEEEVTQLNEAhSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMELEEQHNKEKLNLEEDKNQLQQELENLKEVL 544
Cdd:COG4372 179 AEAEQALDELLKEANRN-AEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVIL 257
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966941256 545 EDKLNTANQEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKETKDALLNVEGELEQERQQHEE 620
Cdd:COG4372 258 KEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALA 333
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
189-382 |
3.14e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 3.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 189 ALEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELhRMEVESLNKMLEELRLEQKKLiedyEGKLNKAQSFYERELDT 268
Cdd:COG4942 38 ELEKELAALKKEEKALLKQLAALERRIAALARRIRAL-EQELAALEAELAELEKEIAEL----RAELEAQKEELAELLRA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 269 LKRSQLFTAESLQASKEKEADLRKEFQGQEAI---LRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENnvqgLQK 345
Cdd:COG4942 113 LYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLapaRREQAEELRADLAELAALRAELEAERAELEALLAELEE----ERA 188
|
170 180 190
....*....|....*....|....*....|....*..
gi 966941256 346 QLDDAKEGEMALLSKHKEVESELAAARERLQQQASDL 382
Cdd:COG4942 189 ALEALKAERQKLLARLEKELAELAAELAELQQEAEEL 225
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
143-474 |
3.19e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.87 E-value: 3.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 143 QLCAEAQHVQ-RIVTMSREVEEIRRKFEEKLRSFGQ-LQVQFEKDKRLALEDLRTAHR---REIQELLKSQQDHSASVNK 217
Cdd:PRK04863 790 QLRAEREELAeRYATLSFDVQKLQRLHQAFSRFIGShLAVAFEADPEAELRQLNRRRVeleRALADHESQEQQQRSQLEQ 869
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 218 GQEKAEELHRM-------EVESLNKMLEELRLEQKKLIEdyegklnkAQSFYERELDTLkrSQLftaeslqaskEKEADL 290
Cdd:PRK04863 870 AKEGLSALNRLlprlnllADETLADRVEEIREQLDEAEE--------AKRFVQQHGNAL--AQL----------EPIVSV 929
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 291 RKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKlQTALATAENnvqglQKQLDDAKEGEMALLSKHKEVESELAA 370
Cdd:PRK04863 930 LQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQR-RAHFSYEDA-----AEMLAKNSDLNEKLRQRLEQAEQERTR 1003
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 371 ARERLQQQASdlvlkashigmlQATQMTQEVTikDLESEKSRANERLSQLEEE-RAFLQSKTQSLDEEQKQQILELEKKV 449
Cdd:PRK04863 1004 AREQLRQAQA------------QLAQYNQVLA--SLKSSYDAKRQMLQELKQElQDLGVPADSGAEERARARRDELHARL 1069
|
330 340 350
....*....|....*....|....*....|..
gi 966941256 450 SEAkRTQQEYYER-------ELKNLQNRLEEE 474
Cdd:PRK04863 1070 SAN-RSRRNQLEKqltfceaEMDNLTKKLRKL 1100
|
|
| Surf_Exclu_PgrA |
TIGR04320 |
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ... |
295-382 |
3.91e-03 |
|
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.
Pssm-ID: 275124 [Multi-domain] Cd Length: 356 Bit Score: 40.87 E-value: 3.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 295 QGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKH-KEVESELAAARE 373
Cdd:TIGR04320 253 PNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTAQNNlATAQAALANAEA 332
|
....*....
gi 966941256 374 RLQQQASDL 382
Cdd:TIGR04320 333 RLAKAKEAL 341
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
286-617 |
3.93e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.16 E-value: 3.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 286 KEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLL---------DKCQKLQTALATA--ENNvqgLQKQLDDAKEGE 354
Cdd:COG3206 101 DKLNLDEDPLGEEASREAAIERLRKNLTVEPVKGSNVIeisytspdpELAAAVANALAEAylEQN---LELRREEARKAL 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 355 MALLSKHKEVESELAAARERLQQqasdlvLKASHIGMLQATQMTQevtikdLESEKSRANERLSQLEEERAFLQSKTQSL 434
Cdd:COG3206 178 EFLEEQLPELRKELEEAEAALEE------FRQKNGLVDLSEEAKL------LLQQLSELESQLAEARAELAEAEARLAAL 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 435 dEEQKQQILELEKKVSEAKRTQQeyYERELKNLQNRLEEEVTQLNEAHSKtleelawkhhmaieavhsnAIRDKKKLQmE 514
Cdd:COG3206 246 -RAQLGSGPDALPELLQSPVIQQ--LRAQLAELEAELAELSARYTPNHPD-------------------VIALRAQIA-A 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 515 LEEQhnkeklnLEEDKNQLQQELENLKEVLEDKLNTANQEIGRLQDLVRKseqglgsaeglIASLQDSQERLQTELDLTK 594
Cdd:COG3206 303 LRAQ-------LQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAE-----------LPELEAELRRLEREVEVAR 364
|
330 340
....*....|....*....|...
gi 966941256 595 DSLketkDALLNVEGELEQERQQ 617
Cdd:COG3206 365 ELY----ESLLQRLEEARLAEAL 383
|
|
| ClyA_Cry6Aa-like |
cd22656 |
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ... |
273-421 |
4.97e-03 |
|
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.
Pssm-ID: 439154 [Multi-domain] Cd Length: 309 Bit Score: 40.43 E-value: 4.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 273 QLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALATAENNVQG-LQKQLDDAK 351
Cdd:cd22656 98 ELIDDLADATDDEELEEAKKTIKALLDDLLKEAKKYQDKAAKVVDKLTDFENQTEKDQTALETLEKALKDlLTDEGGAIA 177
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966941256 352 EGEMALL-----SKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLE 421
Cdd:cd22656 178 RKEIKDLqkeleKLNEEYAAKLKAKIDELKALIADDEAKLAAALRLIADLTAADTDLDNLLALIGPAIPALEKLQ 252
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
229-636 |
5.57e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 40.93 E-value: 5.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 229 EVESLNKMLEELRLEQKKLIEDYEGKLNKAQSfYERELDTLKRSQLFTAESLQaskEKEADLrkefQGQEAILRKTIGKL 308
Cdd:pfam01576 170 EEEEKAKSLSKLKNKHEAMISDLEERLKKEEK-GRQELEKAKRKLEGESTDLQ---EQIAEL----QAQIAELRAQLAKK 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 309 KTELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQ----ASDLVL 384
Cdd:pfam01576 242 EEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTldttAAQQEL 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 385 KA---SHIGMLQAT----QMTQEVTIKDLESEKSRA----NERLSQLEEERAFLQSKTQSLDEEQKQQILELE-----KK 448
Cdd:pfam01576 322 RSkreQEVTELKKAleeeTRSHEAQLQEMRQKHTQAleelTEQLEQAKRNKANLEKAKQALESENAELQAELRtlqqaKQ 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 449 VSEAKRTQQEYYERELKNLQNRLEEEVTQLNEAHSKTLEELAWKHHMaIEAVHSNAIRDKKKLQ---------MELEEQH 519
Cdd:pfam01576 402 DSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSL-LNEAEGKNIKLSKDVSslesqlqdtQELLQEE 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 520 NKEKLN-------LEEDKNQLQQELEN---LKEVLEDKLNTANQEigrLQDLVRKSEQGLGSAEGliasLQDSQERLQTE 589
Cdd:pfam01576 481 TRQKLNlstrlrqLEDERNSLQEQLEEeeeAKRNVERQLSTLQAQ---LSDMKKKLEEDAGTLEA----LEEGKKRLQRE 553
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 966941256 590 LDLTKDSLKE---TKDALLNVEGELEQE------RQQHEETIAAMKEDEKLKVDKM 636
Cdd:pfam01576 554 LEALTQQLEEkaaAYDKLEKTKNRLQQElddllvDLDHQRQLVSNLEKKQKKFDQM 609
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
521-908 |
5.90e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.52 E-value: 5.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 521 KEKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGRLQDLVRKSEQGLGSAEGLI--ASLQDSQERLQTELDLTKDSLK 598
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQelEALEAELAELPERLEELEERLE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 599 ETKDALLNVEgELEQERQQHEETIAAMKEDEKLKVDKMAHDLEIKWtENLRQECSKLREELRlQHEEDKKSAMSQLLQLK 678
Cdd:COG4717 157 ELRELEEELE-ELEAELAELQEELEELLEQLSLATEEELQDLAEEL-EELQQRLAELEEELE-EAQEELEELEEELEQLE 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 679 EREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAF 758
Cdd:COG4717 234 NELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 759 QTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDl 838
Cdd:COG4717 314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALE- 392
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966941256 839 lRHNHHQELAAAKMELERSIDISRRQSKEHMCRIT--DLQEELRHREHHISELDKEVQHLHENISALTKELE 908
Cdd:COG4717 393 -QAEEYQELKEELEELEEQLEELLGELEELLEALDeeELEEELEELEEELEELEEELEELREELAELEAELE 463
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
311-462 |
5.96e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.52 E-value: 5.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 311 ELQMVQDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEGEMALLSKHKEVESELAAARERLQ--QQASDLVLKASH 388
Cdd:COG1579 11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKkyEEQLGNVRNNKE 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966941256 389 IGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFLQSKTQSLDEEQKQQILELEKKVSEAKRTQQEYYER 462
Cdd:COG1579 91 YEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
362-708 |
7.00e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.52 E-value: 7.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 362 KEVESELAAARERLQQQASDLVLKAShigmLQATQMTQEVTIKDLESEKSRAnERLSQLEEERAFLQSKTQSLDEEQKQ- 440
Cdd:COG4717 74 KELEEELKEAEEKEEEYAELQEELEE----LEEELEELEAELEELREELEKL-EKLLQLLPLYQELEALEAELAELPERl 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 441 QILELEKKVSEAKRTQQEYYERELKNLQNRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVhSNAIRDKKKLQMELEEQhn 520
Cdd:COG4717 149 EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRL-AELEEELEEAQEELEEL-- 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 521 KEKLNLEEDKNQLQQELENLKEVLEDKLNTAnqEIGRLQDLVRKSEQGLGSAEGLIASLQDSQERLQTELDLTKDSLKET 600
Cdd:COG4717 226 EEELEQLENELEAAALEERLKEARLLLLIAA--ALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKE 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 601 KDALLNVEGELEQERQQHEETIAAMKEDEKLKVDKMAHDLE-IKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKE 679
Cdd:COG4717 304 AEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDrIEELQELLREAEELEEELQLEELEQEIAALLAEAGVED 383
|
330 340
....*....|....*....|....*....
gi 966941256 680 REKNAARDSWQKKVEDLLNQISLLKQNLE 708
Cdd:COG4717 384 EEELRAALEQAEEYQELKEELEELEEQLE 412
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
287-705 |
7.81e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 40.33 E-value: 7.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 287 EADLRKEFQGQEAI-----LRKTIGKLKTE-LQMV-------QDEAGSLLDKCQKLQTALATAENNVQGLQKQLDDAKEG 353
Cdd:PRK04863 236 EAALRENRMTLEAIrvtqsDRDLFKHLITEsTNYVaadymrhANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 354 EMALLSKHKEVESELAAARERLQ------QQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRANERLSQLEEERAFL 427
Cdd:PRK04863 316 LAELNEAESDLEQDYQAASDHLNlvqtalRQQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDEL 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 428 QSK----TQSLDEEQK-----QQILELEKKVseakRTQQEYYERELKNLQNRLEEEVTQLNEAhskTLEELAWKHHM--- 495
Cdd:PRK04863 396 KSQladyQQALDVQQTraiqyQQAVQALERA----KQLCGLPDLTADNAEDWLEEFQAKEQEA---TEELLSLEQKLsva 468
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 496 -AIEAVHSNAIRDKKKL--QMELEEQHN--KEKL-NLEEDKNQLQQE--LENLKEVLEDKLNTANQEIGRLQDLVRKSEQ 567
Cdd:PRK04863 469 qAAHSQFEQAYQLVRKIagEVSRSEAWDvaRELLrRLREQRHLAEQLqqLRMRLSELEQRLRQQQRAERLLAEFCKRLGK 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 568 GLGSAEGLiaslqdsqERLQTELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEdeklkvdkmahdLEIKWtEN 647
Cdd:PRK04863 549 NLDDEDEL--------EQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAA------------RAPAW-LA 607
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 648 LRQECSKLREELRlQHEEDKKSAMSQLLQL--KEREKNAARDSWQKKVEDLLNQISLLKQ 705
Cdd:PRK04863 608 AQDALARLREQSG-EEFEDSQDVTEYMQQLleRERELTVERDELAARKQALDEEIERLSQ 666
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
44-554 |
9.53e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.28 E-value: 9.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 44 HLKMSKKIAQLTKVIYALNTKNDEHESA-IQALKDAHEEEIQQILAETREKILQYKSKVTEELDLRR--------KIQVL 114
Cdd:COG4913 264 YAAARERLAELEYLRAALRLWFAQRRLElLEAELEELRAELARLEAELERLEARLDALREELDELEAqirgnggdRLEQL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 115 EASLEDHIKMKQQALTEFEAYKHRVEDMQLcAEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLR 194
Cdd:COG4913 344 EREIERLERELEERERRRARLEALLAALGL-PLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELR 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 195 TAhRREIQELLKSQQDHSASVnkgqekaEELHRMEVESLNKMLEELR-----LEQKKLIEDYEGKLnkaqsfyERELDTL 269
Cdd:COG4913 423 EL-EAEIASLERRKSNIPARL-------LALRDALAEALGLDEAELPfvgelIEVRPEEERWRGAI-------ERVLGGF 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 270 KRSQLFTAESLQASKEK--EADLRKEFQGQEAILRktigklKTELQMVQDEAGSLLDKcqklqtaLATAENNVQG-LQKQ 346
Cdd:COG4913 488 ALTLLVPPEHYAAALRWvnRLHLRGRLVYERVRTG------LPDPERPRLDPDSLAGK-------LDFKPHPFRAwLEAE 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 347 L---------DDAKE--------------------GEM---------------------ALLSKHKEVESELAAARER-- 374
Cdd:COG4913 555 LgrrfdyvcvDSPEElrrhpraitragqvkgngtrHEKddrrrirsryvlgfdnraklaALEAELAELEEELAEAEERle 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 375 -LQQQASDLVLKASHIGMLQATQMTQevtiKDLESeksrANERLSQLEEERAFLQSKTQSLdEEQKQQILELEKKVSEAK 453
Cdd:COG4913 635 aLEAELDALQERREALQRLAEYSWDE----IDVAS----AEREIAELEAELERLDASSDDL-AALEEQLEELEAELEELE 705
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 454 RTQqeyyeRELKNLQNRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAirDKKKLQMELEEQHNKEKLNLEEDKNQL 533
Cdd:COG4913 706 EEL-----DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL--EERFAAALGDAVERELRENLEERIDAL 778
|
570 580
....*....|....*....|.
gi 966941256 534 QQELENLKEVLEDKLNTANQE 554
Cdd:COG4913 779 RARLNRAEEELERAMRAFNRE 799
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
184-537 |
9.53e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.28 E-value: 9.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 184 KDKRLALEDLRTAHRREIQELLKSQQDHSASVNKGQEKAEELHRME--------VESLNKMLEELRLEQKKLIEDyegkl 255
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAeyswdeidVASAEREIAELEAELERLDAS----- 683
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 256 nkaqsfyERELDTLKRsqlfTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAT 335
Cdd:COG4913 684 -------SDDLAALEE----QLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE 752
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 336 AEnnvqgLQKQLDDAKEGEMAllskhKEVESELAAARERLQQQASDLVLKashigMLQATQ----MTQEVTIkDLESEkS 411
Cdd:COG4913 753 ER-----FAAALGDAVERELR-----ENLEERIDALRARLNRAEEELERA-----MRAFNRewpaETADLDA-DLESL-P 815
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966941256 412 RANERLSQLEEERAflqsktqsldEEQKQQILELEKKVSEAKRTQ-QEYYERELKNLQNRLEEevtqLNEAhsktLEELA 490
Cdd:COG4913 816 EYLALLDRLEEDGL----------PEYEERFKELLNENSIEFVADlLSKLRRAIREIKERIDP----LNDS----LKRIP 877
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 966941256 491 WKH----HMAIEAVHSNAIRDKKKLQMELEEQHNKEKLNLEEDKNQLQQEL 537
Cdd:COG4913 878 FGPgrylRLEARPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRL 928
|
|
| |
