|
Name |
Accession |
Description |
Interval |
E-value |
| CARMIL_C |
pfam16000 |
CARMIL C-terminus; This domain is found near to the C-terminus of leucine-rich ... |
786-1078 |
1.97e-120 |
|
CARMIL C-terminus; This domain is found near to the C-terminus of leucine-rich repeat-containing proteins in the CARMIL family. In leucine-rich repeat-containing protein 16A (LRRC16A) it includes the region responsible for interaction with F-actin-capping protein subunit alpha-2 (CAPZA2).
:
Pssm-ID: 464966 [Multi-domain] Cd Length: 299 Bit Score: 377.19 E-value: 1.97e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 786 AENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDALSHCHHKLA 865
Cdd:pfam16000 1 AESLCPHVMQKAGVRQDLEKALSEKMTLPEEFVKSTLLEQAGVDIFNKLSEVKLSVASFLSDRIVDEVLEALSRSHHKLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 866 DHFSRRGKTLPQQESL-EIELTEEKPVKRSIITVEeltEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEM-EFDLD 943
Cdd:pfam16000 81 RHLSQRGRTLLEPESLpDGDRPESSPLGPGKRHEG---EIERLEELETPMATLKSKRKSIHSRKLRPVSVAFSVsELDLD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 944 KALEEVPIHIED----PPFPSLRQEK------RSSGFISELPSeEGKKLEHFTKLRPKRNKKQQPTQAAVCAAniVSQDG 1013
Cdd:pfam16000 158 KAPEEVPIHVEDassgPPLPSSSPSEpelsasESLDSLSELPT-EGQKLQHLTKGRPKRNKTRAPTRPPGKVG--PAQDG 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966937398 1014 EQNGHMGRVDEGVDEFFTKKVTKMDSKkwSTRGSESHELNEGGDEKKKRDSRKsSGFLNLIKSRS 1078
Cdd:pfam16000 235 EQNGLSGRVDEGLEDFFSKKVIKLSTP--TSPTSEPSSSSLFPDSPKKRKKRK-SGFFNFIKPRS 296
|
|
| Carm_PH |
pfam17888 |
Carmil pleckstrin homology domain; This is a non-canonical pleckstrin homology (PH) domain ... |
38-119 |
9.91e-36 |
|
Carmil pleckstrin homology domain; This is a non-canonical pleckstrin homology (PH) domain connected to a 16-leucine-rich repeat domain found in CARMIL (CP Arp2/3 complex myosin-I linker) proteins. The PH domain is interconnected with an N-terminal helix (N-helix), residues 10-20 and a C-terminal linker (Linker), residues 129-147 in Swiss:Q6EDY6. Structural and functional studies indicate that the PH domain involved in direct binding to the PM (plasma membrane) and a HD (helical domain) responsible for antiparallel dimerization and enhancement of CARMIL's membrane-binding activity. Furthermore, it appears that CARMIL's PH domain mediates non-specific binding to the membrane, in contrast to other PH domains that bind polyphosphorylated phosphatidylinositides, which are thought to function as signalling lipids.
:
Pssm-ID: 436119 Cd Length: 94 Bit Score: 130.87 E-value: 9.91e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 38 GDKVENKVLVLTSCRAFLVTARIPTKLELTFSYLEIHGVICSKSAQMVVETEKCNISMKMASPEDVSEVLAHIGTCLRKI 117
Cdd:pfam17888 13 GDKVEDRILVLTPWRLFLLSAKVPTKVERTFHFLEIRAINSRNPNQVIVETDKSNYSLKLASEEDVDHVVGHILTALKKI 92
|
..
gi 966937398 118 FP 119
Cdd:pfam17888 93 FP 94
|
|
| RNA1 super family |
cl34950 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
260-658 |
1.98e-17 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
The actual alignment was detected with superfamily member COG5238:
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 86.77 E-value: 1.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 260 IDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQFAKLPKglkHLNLSKTSLSPKGVNSlsqslsanpltastl 339
Cdd:COG5238 94 WEGAEEVSPVALAETATAVATPPPDLRRIMAKTLEDSLILYLALPR---RINLIQVLKDPLGGNA--------------- 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 340 VHLDLSGNVLRGDDLSHMYNFLaQPNAIAHLDLSNTECSLDmvcgallrGCLQYLAVLNLSRTVFShrkgkevppsfkqf 419
Cdd:COG5238 156 VHLLGLAARLGLLAAISMAKAL-QNNSVETVYLGCNQIGDE--------GIEELAEALTQNTTVTT-------------- 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 420 fssslalmhINLSGTKLSPEPLKALLLGLACNHNLKgvSLDLSNCELRSGGAQVLEGCIAEIHNITSLDISDNGL-ESDL 498
Cdd:COG5238 213 ---------LWLKRNPIGDEGAEILAEALKGNKSLT--TLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQIgAEGA 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 499 STLIVWLSKNRSIQHLALgkNFNNMKSKNLTpvldNLVQMIQdEESPLQSLSLADSKLKTEVTI-IINALGSNTSLTKVD 577
Cdd:COG5238 282 IALAKALQGNTTLTSLDL--SVNRIGDEGAI----ALAEGLQ-GNKTLHTLNLAYNGIGAQGAIaLAKALQENTTLHSLD 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 578 ISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKN--YTLRFMPIPMYDASQAlktnpeKTEEALQ 655
Cdd:COG5238 355 LSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTNrlHTLILDGNLIGAEAQQ------RLEQLLE 428
|
...
gi 966937398 656 KIE 658
Cdd:COG5238 429 RIK 431
|
|
| PTZ00449 super family |
cl33186 |
104 kDa microneme/rhoptry antigen; Provisional |
1208-1320 |
3.22e-04 |
|
104 kDa microneme/rhoptry antigen; Provisional
The actual alignment was detected with superfamily member PTZ00449:
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 45.45 E-value: 3.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 1208 GGGAVPKLHPGLPENRFGLGTPEKNTKA-----EPKVEAGSRSRSSSSTPTSPKPllqSPKPSLAARPVIPQKPRTASRP 1282
Cdd:PTZ00449 515 EASGLPPKAPGDKEGEEGEHEDSKESDEpkeggKPGETKEGEVGKKPGPAKEHKP---SKIPTLSKKPEFPKDPKHPKDP 591
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 966937398 1283 DDiPDSPSSPKVALLP--------PVLKKVP-SDKERDGQSSPQ--PSP 1320
Cdd:PTZ00449 592 EE-PKKPKRPRSAQRPtrpkspklPELLDIPkSPKRPESPKSPKrpPPP 639
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CARMIL_C |
pfam16000 |
CARMIL C-terminus; This domain is found near to the C-terminus of leucine-rich ... |
786-1078 |
1.97e-120 |
|
CARMIL C-terminus; This domain is found near to the C-terminus of leucine-rich repeat-containing proteins in the CARMIL family. In leucine-rich repeat-containing protein 16A (LRRC16A) it includes the region responsible for interaction with F-actin-capping protein subunit alpha-2 (CAPZA2).
Pssm-ID: 464966 [Multi-domain] Cd Length: 299 Bit Score: 377.19 E-value: 1.97e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 786 AENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDALSHCHHKLA 865
Cdd:pfam16000 1 AESLCPHVMQKAGVRQDLEKALSEKMTLPEEFVKSTLLEQAGVDIFNKLSEVKLSVASFLSDRIVDEVLEALSRSHHKLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 866 DHFSRRGKTLPQQESL-EIELTEEKPVKRSIITVEeltEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEM-EFDLD 943
Cdd:pfam16000 81 RHLSQRGRTLLEPESLpDGDRPESSPLGPGKRHEG---EIERLEELETPMATLKSKRKSIHSRKLRPVSVAFSVsELDLD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 944 KALEEVPIHIED----PPFPSLRQEK------RSSGFISELPSeEGKKLEHFTKLRPKRNKKQQPTQAAVCAAniVSQDG 1013
Cdd:pfam16000 158 KAPEEVPIHVEDassgPPLPSSSPSEpelsasESLDSLSELPT-EGQKLQHLTKGRPKRNKTRAPTRPPGKVG--PAQDG 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966937398 1014 EQNGHMGRVDEGVDEFFTKKVTKMDSKkwSTRGSESHELNEGGDEKKKRDSRKsSGFLNLIKSRS 1078
Cdd:pfam16000 235 EQNGLSGRVDEGLEDFFSKKVIKLSTP--TSPTSEPSSSSLFPDSPKKRKKRK-SGFFNFIKPRS 296
|
|
| Carm_PH |
pfam17888 |
Carmil pleckstrin homology domain; This is a non-canonical pleckstrin homology (PH) domain ... |
38-119 |
9.91e-36 |
|
Carmil pleckstrin homology domain; This is a non-canonical pleckstrin homology (PH) domain connected to a 16-leucine-rich repeat domain found in CARMIL (CP Arp2/3 complex myosin-I linker) proteins. The PH domain is interconnected with an N-terminal helix (N-helix), residues 10-20 and a C-terminal linker (Linker), residues 129-147 in Swiss:Q6EDY6. Structural and functional studies indicate that the PH domain involved in direct binding to the PM (plasma membrane) and a HD (helical domain) responsible for antiparallel dimerization and enhancement of CARMIL's membrane-binding activity. Furthermore, it appears that CARMIL's PH domain mediates non-specific binding to the membrane, in contrast to other PH domains that bind polyphosphorylated phosphatidylinositides, which are thought to function as signalling lipids.
Pssm-ID: 436119 Cd Length: 94 Bit Score: 130.87 E-value: 9.91e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 38 GDKVENKVLVLTSCRAFLVTARIPTKLELTFSYLEIHGVICSKSAQMVVETEKCNISMKMASPEDVSEVLAHIGTCLRKI 117
Cdd:pfam17888 13 GDKVEDRILVLTPWRLFLLSAKVPTKVERTFHFLEIRAINSRNPNQVIVETDKSNYSLKLASEEDVDHVVGHILTALKKI 92
|
..
gi 966937398 118 FP 119
Cdd:pfam17888 93 FP 94
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
260-658 |
1.98e-17 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 86.77 E-value: 1.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 260 IDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQFAKLPKglkHLNLSKTSLSPKGVNSlsqslsanpltastl 339
Cdd:COG5238 94 WEGAEEVSPVALAETATAVATPPPDLRRIMAKTLEDSLILYLALPR---RINLIQVLKDPLGGNA--------------- 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 340 VHLDLSGNVLRGDDLSHMYNFLaQPNAIAHLDLSNTECSLDmvcgallrGCLQYLAVLNLSRTVFShrkgkevppsfkqf 419
Cdd:COG5238 156 VHLLGLAARLGLLAAISMAKAL-QNNSVETVYLGCNQIGDE--------GIEELAEALTQNTTVTT-------------- 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 420 fssslalmhINLSGTKLSPEPLKALLLGLACNHNLKgvSLDLSNCELRSGGAQVLEGCIAEIHNITSLDISDNGL-ESDL 498
Cdd:COG5238 213 ---------LWLKRNPIGDEGAEILAEALKGNKSLT--TLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQIgAEGA 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 499 STLIVWLSKNRSIQHLALgkNFNNMKSKNLTpvldNLVQMIQdEESPLQSLSLADSKLKTEVTI-IINALGSNTSLTKVD 577
Cdd:COG5238 282 IALAKALQGNTTLTSLDL--SVNRIGDEGAI----ALAEGLQ-GNKTLHTLNLAYNGIGAQGAIaLAKALQENTTLHSLD 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 578 ISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKN--YTLRFMPIPMYDASQAlktnpeKTEEALQ 655
Cdd:COG5238 355 LSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTNrlHTLILDGNLIGAEAQQ------RLEQLLE 428
|
...
gi 966937398 656 KIE 658
Cdd:COG5238 429 RIK 431
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
281-595 |
5.63e-13 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 71.62 E-value: 5.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 281 INLAGNPLEDRGVSSLSiQFAKLPKGLKHLNLS--KTSLSPKGVNSLSQSLSANPLtastLVHLDLSGNVLrGDDLSHMY 358
Cdd:cd00116 28 LRLEGNTLGEEAAKALA-SALRPQPSLKELCLSlnETGRIPRGLQSLLQGLTKGCG----LQELDLSDNAL-GPDGCGVL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 359 NFLAQPNAIAHLDLSNTECS---LDMVCGALlRGCLQYLAVLNLSRTVFSHRKGKEVppsfKQFFSSSLALMHINLSGTK 435
Cdd:cd00116 102 ESLLRSSSLQELKLNNNGLGdrgLRLLAKGL-KDLPPALEKLVLGRNRLEGASCEAL----AKALRANRDLKELNLANNG 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 436 LSPEPLKALLLGLACNHNLKgvSLDLSNCELRSGGAQVLEGCIAEIHNITSLDISDNGLesdlstlivwlsKNRSIQHLA 515
Cdd:cd00116 177 IGDAGIRALAEGLKANCNLE--VLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNL------------TDAGAAALA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 516 LGknfnnMKSKNLTpvldnlvqmiqdeespLQSLSLADSKLKTE-VTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKA 594
Cdd:cd00116 243 SA-----LLSPNIS----------------LLTLSLSCNDITDDgAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAES 301
|
.
gi 966937398 595 L 595
Cdd:cd00116 302 L 302
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
231-583 |
7.97e-05 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 47.15 E-value: 7.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 231 STDVCEQILRVVSRSNRLEELVLENAGLridfAQKLASALAHNPNsgLHTINLAGNPLEdrgvSSLSIQFAKLPKGLKHL 310
Cdd:PLN00113 54 SADVCLWQGITCNNSSRVVSIDLSGKNI----SGKISSAIFRLPY--IQTINLSNNQLS----GPIPDDIFTTSSSLRYL 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 311 NLSKTSLS---PKGVNSLSQSL--SANPLTA---------STLVHLDLSGNVLRGddlsHMYNFLAQPNAIAHLDLSNTE 376
Cdd:PLN00113 124 NLSNNNFTgsiPRGSIPNLETLdlSNNMLSGeipndigsfSSLKVLDLGGNVLVG----KIPNSLTNLTSLEFLTLASNQ 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 377 C--SLDMVCGALLRGCLQYLAVLNLSrtvfshrkgKEVPPSFKQFFS-SSLALMHINLSGtklsPEPlkalllglacnhn 453
Cdd:PLN00113 200 LvgQIPRELGQMKSLKWIYLGYNNLS---------GEIPYEIGGLTSlNHLDLVYNNLTG----PIP------------- 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 454 lkgVSL-DLSNCELRSGGAQVLEGCIA----EIHNITSLDISDNGLESDLSTLIVWLsKNRSIQHLalgknFNNMKSKNL 528
Cdd:PLN00113 254 ---SSLgNLKNLQYLFLYQNKLSGPIPpsifSLQKLISLDLSDNSLSGEIPELVIQL-QNLEILHL-----FSNNFTGKI 324
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 966937398 529 TPVLDNLVQmiqdeespLQSLSLADSKLKTEvtiIINALGSNTSLTKVDISGNGM 583
Cdd:PLN00113 325 PVALTSLPR--------LQVLQLWSNKFSGE---IPKNLGKHNNLTVLDLSTNNL 368
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
1208-1320 |
3.22e-04 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 45.45 E-value: 3.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 1208 GGGAVPKLHPGLPENRFGLGTPEKNTKA-----EPKVEAGSRSRSSSSTPTSPKPllqSPKPSLAARPVIPQKPRTASRP 1282
Cdd:PTZ00449 515 EASGLPPKAPGDKEGEEGEHEDSKESDEpkeggKPGETKEGEVGKKPGPAKEHKP---SKIPTLSKKPEFPKDPKHPKDP 591
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 966937398 1283 DDiPDSPSSPKVALLP--------PVLKKVP-SDKERDGQSSPQ--PSP 1320
Cdd:PTZ00449 592 EE-PKKPKRPRSAQRPtrpkspklPELLDIPkSPKRPESPKSPKrpPPP 639
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CARMIL_C |
pfam16000 |
CARMIL C-terminus; This domain is found near to the C-terminus of leucine-rich ... |
786-1078 |
1.97e-120 |
|
CARMIL C-terminus; This domain is found near to the C-terminus of leucine-rich repeat-containing proteins in the CARMIL family. In leucine-rich repeat-containing protein 16A (LRRC16A) it includes the region responsible for interaction with F-actin-capping protein subunit alpha-2 (CAPZA2).
Pssm-ID: 464966 [Multi-domain] Cd Length: 299 Bit Score: 377.19 E-value: 1.97e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 786 AENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDALSHCHHKLA 865
Cdd:pfam16000 1 AESLCPHVMQKAGVRQDLEKALSEKMTLPEEFVKSTLLEQAGVDIFNKLSEVKLSVASFLSDRIVDEVLEALSRSHHKLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 866 DHFSRRGKTLPQQESL-EIELTEEKPVKRSIITVEeltEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEM-EFDLD 943
Cdd:pfam16000 81 RHLSQRGRTLLEPESLpDGDRPESSPLGPGKRHEG---EIERLEELETPMATLKSKRKSIHSRKLRPVSVAFSVsELDLD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 944 KALEEVPIHIED----PPFPSLRQEK------RSSGFISELPSeEGKKLEHFTKLRPKRNKKQQPTQAAVCAAniVSQDG 1013
Cdd:pfam16000 158 KAPEEVPIHVEDassgPPLPSSSPSEpelsasESLDSLSELPT-EGQKLQHLTKGRPKRNKTRAPTRPPGKVG--PAQDG 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966937398 1014 EQNGHMGRVDEGVDEFFTKKVTKMDSKkwSTRGSESHELNEGGDEKKKRDSRKsSGFLNLIKSRS 1078
Cdd:pfam16000 235 EQNGLSGRVDEGLEDFFSKKVIKLSTP--TSPTSEPSSSSLFPDSPKKRKKRK-SGFFNFIKPRS 296
|
|
| Carm_PH |
pfam17888 |
Carmil pleckstrin homology domain; This is a non-canonical pleckstrin homology (PH) domain ... |
38-119 |
9.91e-36 |
|
Carmil pleckstrin homology domain; This is a non-canonical pleckstrin homology (PH) domain connected to a 16-leucine-rich repeat domain found in CARMIL (CP Arp2/3 complex myosin-I linker) proteins. The PH domain is interconnected with an N-terminal helix (N-helix), residues 10-20 and a C-terminal linker (Linker), residues 129-147 in Swiss:Q6EDY6. Structural and functional studies indicate that the PH domain involved in direct binding to the PM (plasma membrane) and a HD (helical domain) responsible for antiparallel dimerization and enhancement of CARMIL's membrane-binding activity. Furthermore, it appears that CARMIL's PH domain mediates non-specific binding to the membrane, in contrast to other PH domains that bind polyphosphorylated phosphatidylinositides, which are thought to function as signalling lipids.
Pssm-ID: 436119 Cd Length: 94 Bit Score: 130.87 E-value: 9.91e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 38 GDKVENKVLVLTSCRAFLVTARIPTKLELTFSYLEIHGVICSKSAQMVVETEKCNISMKMASPEDVSEVLAHIGTCLRKI 117
Cdd:pfam17888 13 GDKVEDRILVLTPWRLFLLSAKVPTKVERTFHFLEIRAINSRNPNQVIVETDKSNYSLKLASEEDVDHVVGHILTALKKI 92
|
..
gi 966937398 118 FP 119
Cdd:pfam17888 93 FP 94
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
260-658 |
1.98e-17 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 86.77 E-value: 1.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 260 IDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQFAKLPKglkHLNLSKTSLSPKGVNSlsqslsanpltastl 339
Cdd:COG5238 94 WEGAEEVSPVALAETATAVATPPPDLRRIMAKTLEDSLILYLALPR---RINLIQVLKDPLGGNA--------------- 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 340 VHLDLSGNVLRGDDLSHMYNFLaQPNAIAHLDLSNTECSLDmvcgallrGCLQYLAVLNLSRTVFShrkgkevppsfkqf 419
Cdd:COG5238 156 VHLLGLAARLGLLAAISMAKAL-QNNSVETVYLGCNQIGDE--------GIEELAEALTQNTTVTT-------------- 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 420 fssslalmhINLSGTKLSPEPLKALLLGLACNHNLKgvSLDLSNCELRSGGAQVLEGCIAEIHNITSLDISDNGL-ESDL 498
Cdd:COG5238 213 ---------LWLKRNPIGDEGAEILAEALKGNKSLT--TLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQIgAEGA 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 499 STLIVWLSKNRSIQHLALgkNFNNMKSKNLTpvldNLVQMIQdEESPLQSLSLADSKLKTEVTI-IINALGSNTSLTKVD 577
Cdd:COG5238 282 IALAKALQGNTTLTSLDL--SVNRIGDEGAI----ALAEGLQ-GNKTLHTLNLAYNGIGAQGAIaLAKALQENTTLHSLD 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 578 ISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKN--YTLRFMPIPMYDASQAlktnpeKTEEALQ 655
Cdd:COG5238 355 LSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTNrlHTLILDGNLIGAEAQQ------RLEQLLE 428
|
...
gi 966937398 656 KIE 658
Cdd:COG5238 429 RIK 431
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
281-595 |
5.63e-13 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 71.62 E-value: 5.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 281 INLAGNPLEDRGVSSLSiQFAKLPKGLKHLNLS--KTSLSPKGVNSLSQSLSANPLtastLVHLDLSGNVLrGDDLSHMY 358
Cdd:cd00116 28 LRLEGNTLGEEAAKALA-SALRPQPSLKELCLSlnETGRIPRGLQSLLQGLTKGCG----LQELDLSDNAL-GPDGCGVL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 359 NFLAQPNAIAHLDLSNTECS---LDMVCGALlRGCLQYLAVLNLSRTVFSHRKGKEVppsfKQFFSSSLALMHINLSGTK 435
Cdd:cd00116 102 ESLLRSSSLQELKLNNNGLGdrgLRLLAKGL-KDLPPALEKLVLGRNRLEGASCEAL----AKALRANRDLKELNLANNG 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 436 LSPEPLKALLLGLACNHNLKgvSLDLSNCELRSGGAQVLEGCIAEIHNITSLDISDNGLesdlstlivwlsKNRSIQHLA 515
Cdd:cd00116 177 IGDAGIRALAEGLKANCNLE--VLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNL------------TDAGAAALA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 516 LGknfnnMKSKNLTpvldnlvqmiqdeespLQSLSLADSKLKTE-VTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKA 594
Cdd:cd00116 243 SA-----LLSPNIS----------------LLTLSLSCNDITDDgAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAES 301
|
.
gi 966937398 595 L 595
Cdd:cd00116 302 L 302
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
229-373 |
4.38e-12 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 68.92 E-value: 4.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 229 KLSTDVCEQILRVVSRSNRLEELVLENAGLRIDFAQKLASALAHNPNsgLHTINLAGNPLEDRGVSSLSIQFAKLPKgLK 308
Cdd:cd00116 148 RLEGASCEALAKALRANRDLKELNLANNGIGDAGIRALAEGLKANCN--LEVLDLNNNGLTDEGASALAETLASLKS-LE 224
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966937398 309 HLNLSKTSLSPKGVNSLsqsLSANPLTASTLVHLDLSGNVLRGDDLSHMYNFLAQPNAIAHLDLS 373
Cdd:cd00116 225 VLNLGDNNLTDAGAAAL---ASALLSPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLR 286
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
221-466 |
1.28e-11 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 67.38 E-value: 1.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 221 TKLSSKDLKLSTDVCeQILRVVSRSNRLEELVLENAGLRIDFAQKLASALAHNPnSGLHTINLAGNPLEDRGVSSLSIQF 300
Cdd:cd00116 84 QELDLSDNALGPDGC-GVLESLLRSSSLQELKLNNNGLGDRGLRLLAKGLKDLP-PALEKLVLGRNRLEGASCEALAKAL 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 301 AKLPKgLKHLNLSKTSLSPKGVNSLSQSLSANPLtastLVHLDLSGNVLRGDDLSHMYNFLAQPNAIAHLDLSNteCSLD 380
Cdd:cd00116 162 RANRD-LKELNLANNGIGDAGIRALAEGLKANCN----LEVLDLNNNGLTDEGASALAETLASLKSLEVLNLGD--NNLT 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 381 MVCGALL----RGCLQYLAVLNLSRTVFSHRKGKevppSFKQFFSSSLALMHINLSGTKLSPEPLKALLLGLACNHNlKG 456
Cdd:cd00116 235 DAGAAALasalLSPNISLLTLSLSCNDITDDGAK----DLAEVLAEKESLLELDLRGNKFGEEGAQLLAESLLEPGN-EL 309
|
250
....*....|
gi 966937398 457 VSLDLSNCEL 466
Cdd:cd00116 310 ESLWVKDDSF 319
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
246-634 |
2.85e-11 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 67.27 E-value: 2.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 246 NRLEELVLENAGLRIDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSL 325
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 326 SQSLSANPLTA----STLVHLDLSGNvlrgddlshmyNFLAQPNAIAHLDLSNTECSlDMvcGALLRGcLQYLAVLNLSR 401
Cdd:COG4886 81 LLSLLLLGLTDlgdlTNLTELDLSGN-----------EELSNLTNLESLDLSGNQLT-DL--PEELAN-LTNLKELDLSN 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 402 TVFShrkgkEVPPSFKQFfsSSLAlmHINLSGTKLS--PEPLKALllglacnHNLKgvSLDLSNCELRSggaqvLEGCIA 479
Cdd:COG4886 146 NQLT-----DLPEPLGNL--TNLK--SLDLSNNQLTdlPEELGNL-------TNLK--ELDLSNNQITD-----LPEPLG 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 480 EIHNITSLDISDNglesDLSTLIVWLSKNRSIQHLALGKNfnnmkskNLT--PVLDNLVQmiqdeespLQSLSLADSKLK 557
Cdd:COG4886 203 NLTNLEELDLSGN----QLTDLPEPLANLTNLETLDLSNN-------QLTdlPELGNLTN--------LEELDLSNNQLT 263
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966937398 558 TevtiiINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPI 634
Cdd:COG4886 264 D-----LPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLV 335
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
217-481 |
7.87e-10 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 62.89 E-value: 7.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 217 NQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVLENAGLRIDFAQKLASALAHNPNsgLHTINLAGNPLEDRGVSSL 296
Cdd:COG5238 179 NNSVETVYLGCNQIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKS--LTTLDLSNNQIGDEGVIAL 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 297 sIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPltasTLVHLDLSGNVLRGDDLSHMYNFLAQPNAIAHLDLSNte 376
Cdd:COG5238 257 -AEALKNNTTVETLYLSGNQIGAEGAIALAKALQGNT----TLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAY-- 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 377 CSLDMVCGALLRGCLQY---LAVLNLSrtvfSHRKGKEVPPSFKQFFSSSLALMHINLSGTKLSPEPLKALLLGLACNhN 453
Cdd:COG5238 330 NGIGAQGAIALAKALQEnttLHSLDLS----DNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTN-R 404
|
250 260
....*....|....*....|....*...
gi 966937398 454 LKgvSLDLSNCELRSGGAQVLEGCIAEI 481
Cdd:COG5238 405 LH--TLILDGNLIGAEAQQRLEQLLERI 430
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
280-632 |
1.58e-09 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 61.22 E-value: 1.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 280 TINLAGNPLEDRGVSSLsiqFAKLPKgLKHLNLSKTSLSPKGVNSLSQSLSANPltasTLVHLDLSGNVLRGDD--LSHM 357
Cdd:cd00116 2 QLSLKGELLKTERATEL---LPKLLC-LQVLRLEGNTLGEEAAKALASALRPQP----SLKELCLSLNETGRIPrgLQSL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 358 YNFLAQPNAIAHLDLSNTECSLDMVcgALLRGCLQylavlnlsrtvfshrkgkevppsfkqffSSSLALMHINLSGTKLS 437
Cdd:cd00116 74 LQGLTKGCGLQELDLSDNALGPDGC--GVLESLLR----------------------------SSSLQELKLNNNGLGDR 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 438 PEPLKALLLgLACNHNLKgvSLDLSNCELRSGGAQVLEGCIAEIHNITSLDISDNGLESDLstlivwlsknrsIQHLALG 517
Cdd:cd00116 124 GLRLLAKGL-KDLPPALE--KLVLGRNRLEGASCEALAKALRANRDLKELNLANNGIGDAG------------IRALAEG 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 518 knfnnMKsknltpvldnlvqmiqdEESPLQSLSLADSKL-KTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKAL- 595
Cdd:cd00116 189 -----LK-----------------ANCNLEVLDLNNNGLtDEGASALAETLASLKSLEVLNLGDNNLTDAGAAALASALl 246
|
330 340 350
....*....|....*....|....*....|....*..
gi 966937398 596 QINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFM 632
Cdd:cd00116 247 SPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLEL 283
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
457-647 |
4.54e-08 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 56.59 E-value: 4.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 457 VSLDLSNCELRSGGAQVLEGCIAEIHNITSLDISDNGLESDLSTLIVWLS---KNRSIQHLALgknFNNMKSKNLTPVLD 533
Cdd:cd00116 26 QVLRLEGNTLGEEAAKALASALRPQPSLKELCLSLNETGRIPRGLQSLLQgltKGCGLQELDL---SDNALGPDGCGVLE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 534 NLVQmiqdeESPLQSLSLADSKL-KTEVTIIINALGSNT-SLTKVDISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNI 611
Cdd:cd00116 103 SLLR-----SSSLQELKLNNNGLgDRGLRLLAKGLKDLPpALEKLVLGRNRLEGASCEALAKALRANRDLKELNLANNGI 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 966937398 612 TAQGFQDIAVAMEKNYTLR--------FMPIPMYDASQALKTNP 647
Cdd:cd00116 178 GDAGIRALAEGLKANCNLEvldlnnngLTDEGASALAETLASLK 221
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
187-347 |
1.38e-07 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 55.57 E-value: 1.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 187 LTQDT--RELNLQDfSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVLEnaGLRIDF-- 262
Cdd:COG5238 204 LTQNTtvTTLWLKR-NPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTVETLYLS--GNQIGAeg 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 263 AQKLASALAHNPNsgLHTINLAGNPLEDRGVSSLsIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPltasTLVHL 342
Cdd:COG5238 281 AIALAKALQGNTT--LTSLDLSVNRIGDEGAIAL-AEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQENT----TLHSL 353
|
....*
gi 966937398 343 DLSGN 347
Cdd:COG5238 354 DLSDN 358
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
231-583 |
7.97e-05 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 47.15 E-value: 7.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 231 STDVCEQILRVVSRSNRLEELVLENAGLridfAQKLASALAHNPNsgLHTINLAGNPLEdrgvSSLSIQFAKLPKGLKHL 310
Cdd:PLN00113 54 SADVCLWQGITCNNSSRVVSIDLSGKNI----SGKISSAIFRLPY--IQTINLSNNQLS----GPIPDDIFTTSSSLRYL 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 311 NLSKTSLS---PKGVNSLSQSL--SANPLTA---------STLVHLDLSGNVLRGddlsHMYNFLAQPNAIAHLDLSNTE 376
Cdd:PLN00113 124 NLSNNNFTgsiPRGSIPNLETLdlSNNMLSGeipndigsfSSLKVLDLGGNVLVG----KIPNSLTNLTSLEFLTLASNQ 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 377 C--SLDMVCGALLRGCLQYLAVLNLSrtvfshrkgKEVPPSFKQFFS-SSLALMHINLSGtklsPEPlkalllglacnhn 453
Cdd:PLN00113 200 LvgQIPRELGQMKSLKWIYLGYNNLS---------GEIPYEIGGLTSlNHLDLVYNNLTG----PIP------------- 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 454 lkgVSL-DLSNCELRSGGAQVLEGCIA----EIHNITSLDISDNGLESDLSTLIVWLsKNRSIQHLalgknFNNMKSKNL 528
Cdd:PLN00113 254 ---SSLgNLKNLQYLFLYQNKLSGPIPpsifSLQKLISLDLSDNSLSGEIPELVIQL-QNLEILHL-----FSNNFTGKI 324
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 966937398 529 TPVLDNLVQmiqdeespLQSLSLADSKLKTEvtiIINALGSNTSLTKVDISGNGM 583
Cdd:PLN00113 325 PVALTSLPR--------LQVLQLWSNKFSGE---IPKNLGKHNNLTVLDLSTNNL 368
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
1208-1320 |
3.22e-04 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 45.45 E-value: 3.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966937398 1208 GGGAVPKLHPGLPENRFGLGTPEKNTKA-----EPKVEAGSRSRSSSSTPTSPKPllqSPKPSLAARPVIPQKPRTASRP 1282
Cdd:PTZ00449 515 EASGLPPKAPGDKEGEEGEHEDSKESDEpkeggKPGETKEGEVGKKPGPAKEHKP---SKIPTLSKKPEFPKDPKHPKDP 591
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 966937398 1283 DDiPDSPSSPKVALLP--------PVLKKVP-SDKERDGQSSPQ--PSP 1320
Cdd:PTZ00449 592 EE-PKKPKRPRSAQRPtrpkspklPELLDIPkSPKRPESPKSPKrpPPP 639
|
|
| |
