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Conserved domains on  [gi|966935648|ref|XP_014990401|]
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kelch domain-containing protein 10 isoform X3 [Macaca mulatta]

Protein Classification

Kelch repeat-containing protein( domain architecture ID 19803719)

Kelch repeat-containing protein, member of a superfamily of proteins with diverse functions

CATH:  2.120.10.80
Gene Ontology:  GO:0005515
PubMed:  10603472|31442578|24959344
SCOP:  3000448

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
190-362 7.47e-27

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 108.32  E-value: 7.47e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 190 AMAIINGSLYVFGGTTGYIYSTDLHKLDLNTREWTQLKPnnlscdLPEERYRHEIA--HDGqRIYILGGGTSWTAYS--L 265
Cdd:COG3055   17 AAALLDGKVYVAGGLSGGSASNSFEVYDPATNTWSELAP------LPGPPRHHAAAvaQDG-KLYVFGGFTGANPSStpL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 266 NKIHAYNLETNAWEEIATkphekigFPAARRCHSCVQIKNDVFICGGYNGEVILGDIWKLNLQTFQWVKLPAtMPEPVYF 345
Cdd:COG3055   90 NDVYVYDPATNTWTKLAP-------MPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAP-LPTPRDH 161

                        170
                 ....*....|....*..
gi 966935648 346 HCAAVTPAGCMYIHGGV 362
Cdd:COG3055  162 LAAAVLPDGKILVIGGR 178
NanM super family cl34543
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
62-164 2.96e-06

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG3055:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 48.61  E-value: 2.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  62 TSCHRPPPARSGHRCVADNTNLYVFGGYnpdydesggpdnedYPLFRELWRYHFATGVWHQMGTdgyMPRELASMSLVLH 141
Cdd:COG3055  188 TTLAPLPTARAGHAAAVLGGKILVFGGE--------------SGFSDEVEAYDPATNTWTALGE---LPTPRHGHAAVLT 250

                         90       100
                 ....*....|....*....|...
gi 966935648 142 GNNLLVFGGTGIPFGESNGNDVH 164
Cdd:COG3055  251 DGKVYVIGGETKPGVRTPLVTSA 273
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
190-362 7.47e-27

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 108.32  E-value: 7.47e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 190 AMAIINGSLYVFGGTTGYIYSTDLHKLDLNTREWTQLKPnnlscdLPEERYRHEIA--HDGqRIYILGGGTSWTAYS--L 265
Cdd:COG3055   17 AAALLDGKVYVAGGLSGGSASNSFEVYDPATNTWSELAP------LPGPPRHHAAAvaQDG-KLYVFGGFTGANPSStpL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 266 NKIHAYNLETNAWEEIATkphekigFPAARRCHSCVQIKNDVFICGGYNGEVILGDIWKLNLQTFQWVKLPAtMPEPVYF 345
Cdd:COG3055   90 NDVYVYDPATNTWTKLAP-------MPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAP-LPTPRDH 161

                        170
                 ....*....|....*..
gi 966935648 346 HCAAVTPAGCMYIHGGV 362
Cdd:COG3055  162 LAAAVLPDGKILVIGGR 178
PLN02153 PLN02153
epithiospecifier protein
 118-281 1.48e-11

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 65.39  E-value: 1.48e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 118 GVW---HQMGTDGYMPRELASMSLVlhGNNLLVFGGTGIPfGESNGNDVHVCNVKYKRWALLSCRGKKPS-RIYGQAMAI 193
Cdd:PLN02153   7 GGWikvEQKGGKGPGPRCSHGIAVV--GDKLYSFGGELKP-NEHIDKDLYVFDFNTHTWSIAPANGDVPRiSCLGVRMVA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 194 INGSLYVFGGTTGYIYSTDLHKLDLNTREWTQLKPNNLSCDlPEERYRHEIAHDGQRIYILG----GGTSWTAYSLNKIH 269
Cdd:PLN02153  84 VGTKLYIFGGRDEKREFSDFYSYDTVKNEWTFLTKLDEEGG-PEARTFHSMASDENHVYVFGgvskGGLMKTPERFRTIE 162

                        170
                 ....*....|..
gi 966935648 270 AYNLETNAWEEI 281
Cdd:PLN02153 163 AYNIADGKWVQL 174
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 294-340 4.83e-08

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 48.76  E-value: 4.83e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 966935648  294 ARRCHSCVQIKNDVFICGGYNGEVILGDIWKLNLQTFQWVKLPaTMP 340
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKLP-SMP 46
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
62-164 2.96e-06

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 48.61  E-value: 2.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  62 TSCHRPPPARSGHRCVADNTNLYVFGGYnpdydesggpdnedYPLFRELWRYHFATGVWHQMGTdgyMPRELASMSLVLH 141
Cdd:COG3055  188 TTLAPLPTARAGHAAAVLGGKILVFGGE--------------SGFSDEVEAYDPATNTWTALGE---LPTPRHGHAAVLT 250

                         90       100
                 ....*....|....*....|...
gi 966935648 142 GNNLLVFGGTGIPFGESNGNDVH 164
Cdd:COG3055  251 DGKVYVIGGETKPGVRTPLVTSA 273
PLN02153 PLN02153
epithiospecifier protein
 68-237 3.85e-06

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 48.44  E-value: 3.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  68 PPARSGHRCVADNTNLYVFGGYNpdydeSGGPDNEDyPLFRELWRYHFATGVWHQMGTDG--YMPRELASMsLVLHGNNL 145
Cdd:PLN02153 125 PEARTFHSMASDENHVYVFGGVS-----KGGLMKTP-ERFRTIEAYNIADGKWVQLPDPGenFEKRGGAGF-AVVQGKIW 197

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 146 LVFG--GTGIPFGESN--GNDVHVCNVKYKRWALLSCRGKKPSRIYGQAMAIINGSLYVFGGTT-----GYI----YSTD 212
Cdd:PLN02153 198 VVYGfaTSILPGGKSDyeSNAVQFFDPASGKWTEVETTGAKPSARSVFAHAVVGKYIIIFGGEVwpdlkGHLgpgtLSNE 277

                        170       180
                 ....*....|....*....|....*
gi 966935648 213 LHKLDLNTREWTQLKpnnlSCDLPE 237
Cdd:PLN02153 278 GYALDTETLVWEKLG----ECGEPA 298
Kelch smart00612
Kelch domain;
307-351 1.02e-04

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 39.46  E-value: 1.02e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 966935648   307 VFICGGYNGEVILGDIWKLNLQTFQWVKLPAtMPEPVYFHCAAVT 351
Cdd:smart00612   2 IYVVGGFDGGQRLKSVEVYDPETNKWTPLPS-MPTPRSGHGVAVI 45
Kelch_4 pfam13418
Galactose oxidase, central domain;
70-125 3.74e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 37.98  E-value: 3.74e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 966935648   70 ARSGHRCVA-DNTNLYVFGGYNpdydesggpdnEDYPLFRELWRYHFATGVWHQMGT 125
Cdd:pfam13418   1 PRAYHTSTSiPDDTIYLFGGEG-----------EDGTLLSDLWVFDLSTNEWTRLGS 46
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
190-362 7.47e-27

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 108.32  E-value: 7.47e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 190 AMAIINGSLYVFGGTTGYIYSTDLHKLDLNTREWTQLKPnnlscdLPEERYRHEIA--HDGqRIYILGGGTSWTAYS--L 265
Cdd:COG3055   17 AAALLDGKVYVAGGLSGGSASNSFEVYDPATNTWSELAP------LPGPPRHHAAAvaQDG-KLYVFGGFTGANPSStpL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 266 NKIHAYNLETNAWEEIATkphekigFPAARRCHSCVQIKNDVFICGGYNGEVILGDIWKLNLQTFQWVKLPAtMPEPVYF 345
Cdd:COG3055   90 NDVYVYDPATNTWTKLAP-------MPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAP-LPTPRDH 161

                        170
                 ....*....|....*..
gi 966935648 346 HCAAVTPAGCMYIHGGV 362
Cdd:COG3055  162 LAAAVLPDGKILVIGGR 178
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
68-380 8.51e-27

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 108.32  E-value: 8.51e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  68 PPARSGHRCVADNTNLYVFGGYNpdydeSGGPDNEdyplfreLWRYHFATGVWHQMGTDGYMPRELASMslVLHGNNLLV 147
Cdd:COG3055   10 PTPRSEAAAALLDGKVYVAGGLS-----GGSASNS-------FEVYDPATNTWSELAPLPGPPRHHAAA--VAQDGKLYV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 148 FGGTGIPFGESNG-NDVHVCNVKYKRWallSCRGKKPSRIYGQAMAIINGSLYVFGGTTGYIYSTDLHKLDLNTREWTQL 226
Cdd:COG3055   76 FGGFTGANPSSTPlNDVYVYDPATNTW---TKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 227 KPnnlscdLPEERYRHE-IAHDGQRIYILGGGTSwtayslnkihayNLETNAWEEIATKPHekigfpaARRCHSCVQIKN 305
Cdd:COG3055  153 AP------LPTPRDHLAaAVLPDGKILVIGGRNG------------SGFSNTWTTLAPLPT-------ARAGHAAAVLGG 207

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966935648 306 DVFICGGYNGevILGDIWKLNLQTFQWVKLPaTMPEPVYFHcAAVTPAGCMYIHGGvvnihENKRTGSLFKIWLV 380
Cdd:COG3055  208 KILVFGGESG--FSDEVEAYDPATNTWTALG-ELPTPRHGH-AAVLTDGKVYVIGG-----ETKPGVRTPLVTSA 273
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
67-314 1.10e-25

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 105.24  E-value: 1.10e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  67 PPPARSGHRCVADNTNLYVFGGYNPDYDESGgpdnedypLFRELWRYHFATGVWHQMGTdgyMPRELASMSLVLHGNNLL 146
Cdd:COG3055   57 PGPPRHHAAAVAQDGKLYVFGGFTGANPSST--------PLNDVYVYDPATNTWTKLAP---MPTPRGGATALLLDGKIY 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 147 VFGGTGipfGESNGNDVHVCNVKYKRWallSCRGKKPSRIYGQAMAII-NGSLYVFGGTTGYIYSTdlhkldlntrEWTQ 225
Cdd:COG3055  126 VVGGWD---DGGNVAWVEVYDPATGTW---TQLAPLPTPRDHLAAAVLpDGKILVIGGRNGSGFSN----------TWTT 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 226 LKPnnlscdLPEERYRHEIAHDGQRIYILGGGTSWtaysLNKIHAYNLETNAWEEIATkphekigFPAARRCHSCVQIKN 305
Cdd:COG3055  190 LAP------LPTARAGHAAAVLGGKILVFGGESGF----SDEVEAYDPATNTWTALGE-------LPTPRHGHAAVLTDG 252


                 ....*....
gi 966935648 306 DVFICGGYN 314
Cdd:COG3055  253 KVYVIGGET 261
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
222-369 3.23e-14

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 72.50  E-value: 3.23e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 222 EWTQLKpnnlscDLPEERYRHEIAHDGQRIYILGGGTSWTAysLNKIHAYNLETNAWEEIATkphekigFPAARRCHSCV 301
Cdd:COG3055    2 TWSSLP------DLPTPRSEAAAALLDGKVYVAGGLSGGSA--SNSFEVYDPATNTWSELAP-------LPGPPRHHAAA 66

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966935648 302 Q-IKNDVFICGGYNG----EVILGDIWKLNLQTFQWVKLPaTMPEPVYFHcAAVTPAGCMYIHGGVVNIHENK 369
Cdd:COG3055   67 VaQDGKLYVFGGFTGanpsSTPLNDVYVYDPATNTWTKLA-PMPTPRGGA-TALLLDGKIYVVGGWDDGGNVA 137
PLN02153 PLN02153
epithiospecifier protein
 118-281 1.48e-11

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 65.39  E-value: 1.48e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 118 GVW---HQMGTDGYMPRELASMSLVlhGNNLLVFGGTGIPfGESNGNDVHVCNVKYKRWALLSCRGKKPS-RIYGQAMAI 193
Cdd:PLN02153   7 GGWikvEQKGGKGPGPRCSHGIAVV--GDKLYSFGGELKP-NEHIDKDLYVFDFNTHTWSIAPANGDVPRiSCLGVRMVA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 194 INGSLYVFGGTTGYIYSTDLHKLDLNTREWTQLKPNNLSCDlPEERYRHEIAHDGQRIYILG----GGTSWTAYSLNKIH 269
Cdd:PLN02153  84 VGTKLYIFGGRDEKREFSDFYSYDTVKNEWTFLTKLDEEGG-PEARTFHSMASDENHVYVFGgvskGGLMKTPERFRTIE 162

                        170
                 ....*....|..
gi 966935648 270 AYNLETNAWEEI 281
Cdd:PLN02153 163 AYNIADGKWVQL 174
PLN02193 PLN02193
nitrile-specifier protein
 118-315 3.31e-10

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 61.51  E-value: 3.31e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 118 GVWHQMGTDGYMPRELASMSLVLHGNNLLVFGGTGIPfGESNGNDVHVCNVKYKRWALLSCRGKKPS-RIYGQAMAIING 196
Cdd:PLN02193 151 GKWIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGEFTP-NQPIDKHLYVFDLETRTWSISPATGDVPHlSCLGVRMVSIGS 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 197 SLYVFGGTTGYIYSTDLHKLDLNTREWTQLKPNNlscDLPEERYRHEIAHDGQRIYILgGGTSWTAySLNKIHAYNLETN 276
Cdd:PLN02193 230 TLYVFGGRDASRQYNGFYSFDTTTNEWKLLTPVE---EGPTPRSFHSMAADEENVYVF-GGVSATA-RLKTLDSYNIVDK 304

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 966935648 277 AWEEIATkPHEKIgfpAARRCHSCVQIKNDVFICGGYNG 315
Cdd:PLN02193 305 KWFHCST-PGDSF---SIRGGAGLEVVQGKVWVVYGFNG 339
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 294-340 4.83e-08

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 48.76  E-value: 4.83e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 966935648  294 ARRCHSCVQIKNDVFICGGYNGEVILGDIWKLNLQTFQWVKLPaTMP 340
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKLP-SMP 46
PLN02153 PLN02153
epithiospecifier protein
 180-336 6.35e-08

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 54.22  E-value: 6.35e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 180 GKKPSRIYGQAMAIINGSLYVFGG--TTGYIYSTDLHKLDLNTREWTQLKPNNlscDLPE-ERYRHEIAHDGQRIYILGG 256
Cdd:PLN02153  17 GKGPGPRCSHGIAVVGDKLYSFGGelKPNEHIDKDLYVFDFNTHTWSIAPANG---DVPRiSCLGVRMVAVGTKLYIFGG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 257 GTSWTAYslNKIHAYNLETNAWEeIATKPHEKiGFPAARRCHSCVQIKNDVFICGGYNGEVILG------DIWKLNLQTF 330
Cdd:PLN02153  94 RDEKREF--SDFYSYDTVKNEWT-FLTKLDEE-GGPEARTFHSMASDENHVYVFGGVSKGGLMKtperfrTIEAYNIADG 169


                 ....*.
gi 966935648 331 QWVKLP 336
Cdd:PLN02153 170 KWVQLP 175
Kelch_4 pfam13418
Galactose oxidase, central domain;
294-341 1.74e-07

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 47.61  E-value: 1.74e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 966935648  294 ARRCHSCVQIKND-VFICGGYNGE-VILGDIWKLNLQTFQWVKLPaTMPE 341
Cdd:pfam13418   1 PRAYHTSTSIPDDtIYLFGGEGEDgTLLSDLWVFDLSTNEWTRLG-SLPS 49
Kelch_3 pfam13415
Galactose oxidase, central domain;
248-303 4.20e-07

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 46.51  E-value: 4.20e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 966935648  248 GQRIYILGGGTSWTAYSLNKIHAYNLETNAWEEIATKphekigfPAARRCHSCVQI 303
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRLNDLYVYDLDTNTWTQIGDL-------PPPRSGHSATYI 49
PLN02193 PLN02193
nitrile-specifier protein
 138-361 7.60e-07

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 51.11  E-value: 7.60e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 138 LVLHGNNLLVFGGTGIPFGESNGNDVHVCNVK--YKRWALLSCRGKKPSRIYGQAMAIINGSLYVFGG--TTGYIYSTDL 213
Cdd:PLN02193 116 FVLQGGKIVGFHGRSTDVLHSLGAYISLPSTPklLGKWIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGefTPNQPIDKHL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 214 HKLDLNTREWTqLKPN-----NLSCdlpeerYRHEIAHDGQRIYILGGGTSWTAYslNKIHAYNLETNAWEEIAtkPHEK 288
Cdd:PLN02193 196 YVFDLETRTWS-ISPAtgdvpHLSC------LGVRMVSIGSTLYVFGGRDASRQY--NGFYSFDTTTNEWKLLT--PVEE 264

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966935648 289 igFPAARRCHSCVQIKNDVFICGGYNGEVILGDIWKLNLQTFQWvklpatmpepvyFHCAavTPAGCMYIHGG 361
Cdd:PLN02193 265 --GPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNIVDKKW------------FHCS--TPGDSFSIRGG 321
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
62-164 2.96e-06

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 48.61  E-value: 2.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  62 TSCHRPPPARSGHRCVADNTNLYVFGGYnpdydesggpdnedYPLFRELWRYHFATGVWHQMGTdgyMPRELASMSLVLH 141
Cdd:COG3055  188 TTLAPLPTARAGHAAAVLGGKILVFGGE--------------SGFSDEVEAYDPATNTWTALGE---LPTPRHGHAAVLT 250

                         90       100
                 ....*....|....*....|...
gi 966935648 142 GNNLLVFGGTGIPFGESNGNDVH 164
Cdd:COG3055  251 DGKVYVIGGETKPGVRTPLVTSA 273
PHA03098 PHA03098
kelch-like protein; Provisional
 70-279 3.26e-06

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 49.38  E-value: 3.26e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  70 ARSGHRCVADNTNLYVFGGYnpdydesggpDNEDYPLFRELWRyhFATGVWhQMGTDGYMPRelASMSLVLHGNNLLVFG 149
Cdd:PHA03098 332 PRKNPGVTVFNNRIYVIGGI----------YNSISLNTVESWK--PGESKW-REEPPLIFPR--YNPCVVNVNNLIYVIG 396

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 150 GtgIPFGESNGNDVHVCNVKYKRWALLSCrgkKPSRIYGQAMAIINGSLYVFGGTTgyiYSTDLHKL------DLNTREW 223
Cdd:PHA03098 397 G--ISKNDELLKTVECFSLNTNKWSKGSP---LPISHYGGCAIYHDGKIYVIGGIS---YIDNIKVYnivesyNPVTNKW 468

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 966935648 224 TQLKPNNLScdlpeeRYRHEIAHDGQRIYILGGGTSwtAYSLNKIHAYNLETNAWE 279
Cdd:PHA03098 469 TELSSLNFP------RINASLCIFNNKIYVVGGDKY--EYYINEIEVYDDKTNTWT 516
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 239-285 3.27e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 43.75  E-value: 3.27e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 966935648  239 RYRHEIAHDGQRIYILGGGTSWTaySLNKIHAYNLETNAWEEIATKP 285
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFDGNQ--SLNSVEVYDPETNTWSKLPSMP 46
PLN02153 PLN02153
epithiospecifier protein
 68-237 3.85e-06

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 48.44  E-value: 3.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  68 PPARSGHRCVADNTNLYVFGGYNpdydeSGGPDNEDyPLFRELWRYHFATGVWHQMGTDG--YMPRELASMsLVLHGNNL 145
Cdd:PLN02153 125 PEARTFHSMASDENHVYVFGGVS-----KGGLMKTP-ERFRTIEAYNIADGKWVQLPDPGenFEKRGGAGF-AVVQGKIW 197

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 146 LVFG--GTGIPFGESN--GNDVHVCNVKYKRWALLSCRGKKPSRIYGQAMAIINGSLYVFGGTT-----GYI----YSTD 212
Cdd:PLN02153 198 VVYGfaTSILPGGKSDyeSNAVQFFDPASGKWTEVETTGAKPSARSVFAHAVVGKYIIIFGGEVwpdlkGHLgpgtLSNE 277

                        170       180
                 ....*....|....*....|....*
gi 966935648 213 LHKLDLNTREWTQLKpnnlSCDLPE 237
Cdd:PLN02153 278 GYALDTETLVWEKLG----ECGEPA 298
Kelch_4 pfam13418
Galactose oxidase, central domain;
185-228 5.51e-06

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 43.37  E-value: 5.51e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 966935648  185 RIYGQAMAIINGSLYVFGGTT--GYIYStDLHKLDLNTREWTQLKP 228
Cdd:pfam13418   2 RAYHTSTSIPDDTIYLFGGEGedGTLLS-DLWVFDLSTNEWTRLGS 46
PLN02193 PLN02193
nitrile-specifier protein
 73-256 1.29e-05

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 47.26  E-value: 1.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  73 GHRCVADNTNLYVFGGYNPDYDESGgpdnedyplfreLWRYHFATGVWHQMG--TDGYMPRELASMSlvLHGNNLLVFGG 150
Cdd:PLN02193 221 GVRMVSIGSTLYVFGGRDASRQYNG------------FYSFDTTTNEWKLLTpvEEGPTPRSFHSMA--ADEENVYVFGG 286

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 151 TGipfGESNGNDVHVCNVKYKRWALLSCRGKKPSRIYGQAMAIINGSLYVFGGTTGyIYSTDLHKLDLNTREWTQLKPNN 230
Cdd:PLN02193 287 VS---ATARLKTLDSYNIVDKKWFHCSTPGDSFSIRGGAGLEVVQGKVWVVYGFNG-CEVDDVHYYDPVQDKWTQVETFG 362

                        170       180
                 ....*....|....*....|....*.
gi 966935648 231 LScdlPEERYRHEIAHDGQRIYILGG 256
Cdd:PLN02193 363 VR---PSERSVFASAAVGKHIVIFGG 385
Kelch_6 pfam13964
Kelch motif;
239-286 1.88e-05

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 41.94  E-value: 1.88e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 966935648  239 RYRHEIAHDGQRIYILGGGTSWTAYSlNKIHAYNLETNAWEEIATKPH 286
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTNASPAL-NKLEVYNPLTKSWEELPPLPT 48
PRK14131 PRK14131
N-acetylneuraminate epimerase;
245-362 2.39e-05

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 46.16  E-value: 2.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 245 AHDGQRIYI-LG-GGTSWTAYSLNKIHAynletnAWEEIATkphekigFPAARRCHS-CVQIKNDVFICGGY-----NGE 316
Cdd:PRK14131  35 AIDNNTVYVgLGsAGTSWYKLDLNAPSK------GWTKIAA-------FPGGPREQAvAAFIDGKLYVFGGIgktnsEGS 101

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 966935648 317 VIL-GDIWKLNLQTFQWVKLPATMPEPVYFHcAAVTPAGCM-YIHGGV 362
Cdd:PRK14131 102 PQVfDDVYKYDPKTNSWQKLDTRSPVGLAGH-VAVSLHNGKaYITGGV 148
PRK14131 PRK14131
N-acetylneuraminate epimerase;
67-150 3.78e-05

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 45.39  E-value: 3.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  67 PPPARSGHRCVADNTNLYVFGGynpdydeSGGPDNEDYP-LFRELWRYHFATGVWHQMGTDGymPRELA-SMSLVLHGNN 144
Cdd:PRK14131  71 PGGPREQAVAAFIDGKLYVFGG-------IGKTNSEGSPqVFDDVYKYDPKTNSWQKLDTRS--PVGLAgHVAVSLHNGK 141


                 ....*.
gi 966935648 145 LLVFGG 150
Cdd:PRK14131 142 AYITGG 147
PHA03098 PHA03098
kelch-like protein; Provisional
 161-336 4.72e-05

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 45.53  E-value: 4.72e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 161 NDVHVCNVKYKRWallscrGKKPSRIY---GQAMAIINGSLYVFGGTTGYIYSTDLHKLDLNTREWTQLKPnnlscdLPE 237
Cdd:PHA03098 311 NSVVSYDTKTKSW------NKVPELIYprkNPGVTVFNNRIYVIGGIYNSISLNTVESWKPGESKWREEPP------LIF 378

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 238 ERYRHEIAHDGQRIYILgGGTSWTAYSLNKIHAYNLETNAWEEIATKPHEKIGfpaarrcHSCVQIKNDVFICGGY---N 314
Cdd:PHA03098 379 PRYNPCVVNVNNLIYVI-GGISKNDELLKTVECFSLNTNKWSKGSPLPISHYG-------GCAIYHDGKIYVIGGIsyiD 450

                        170       180
                 ....*....|....*....|..
gi 966935648 315 GEVILGDIWKLNLQTFQWVKLP 336
Cdd:PHA03098 451 NIKVYNIVESYNPVTNKWTELS 472
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 187-230 4.88e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 40.29  E-value: 4.88e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 966935648  187 YGQAMAIINGSLYVFGGTTGYIYSTDLHKLDLNTREWTQLKPNN 230
Cdd:pfam01344   3 SGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKLPSMP 46
Kelch smart00612
Kelch domain;
307-351 1.02e-04

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 39.46  E-value: 1.02e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 966935648   307 VFICGGYNGEVILGDIWKLNLQTFQWVKLPAtMPEPVYFHCAAVT 351
Cdd:smart00612   2 IYVVGGFDGGQRLKSVEVYDPETNKWTPLPS-MPTPRSGHGVAVI 45
PRK14131 PRK14131
N-acetylneuraminate epimerase;
183-314 1.17e-04

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 43.85  E-value: 1.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 183 PSRIYGQAMAIINGSLYVFGGTTGyiysTDLHKLDLNT--REWTQLKpnnlscDLP-EERYRHEIAHDGQRIYILGG-GT 258
Cdd:PRK14131  26 PVPFKNGTGAIDNNTVYVGLGSAG----TSWYKLDLNApsKGWTKIA------AFPgGPREQAVAAFIDGKLYVFGGiGK 95

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 259 SWTAYSL---NKIHAYNLETNAWEEIATKPhekigfPAARRCHSCVQIKND-VFICGGYN 314
Cdd:PRK14131  96 TNSEGSPqvfDDVYKYDPKTNSWQKLDTRS------PVGLAGHVAVSLHNGkAYITGGVN 149
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 236-276 2.11e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 38.70  E-value: 2.11e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 966935648  236 PEERYRHEIAHDGQRIYILGGGTSWTAYSLNKIHAYNLETN 276
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQPSDDVYVLSLPTF 41
Kelch_4 pfam13418
Galactose oxidase, central domain;
70-125 3.74e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 37.98  E-value: 3.74e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 966935648   70 ARSGHRCVA-DNTNLYVFGGYNpdydesggpdnEDYPLFRELWRYHFATGVWHQMGT 125
Cdd:pfam13418   1 PRAYHTSTSiPDDTIYLFGGEG-----------EDGTLLSDLWVFDLSTNEWTRLGS 46
Kelch_6 pfam13964
Kelch motif;
294-342 3.88e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 38.09  E-value: 3.88e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 966935648  294 ARRCHSCVQIKNDVFICGGY-NGEVILGDIWKLNLQTFQWVKLPaTMPEP 342
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYtNASPALNKLEVYNPLTKSWEELP-PLPTP 49
Kelch_4 pfam13418
Galactose oxidase, central domain;
244-286 5.77e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 37.59  E-value: 5.77e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 966935648  244 IAHDGQRIYILGGgTSWTAYSLNKIHAYNLETNAWEEIATKPH 286
Cdd:pfam13418   8 TSIPDDTIYLFGG-EGEDGTLLSDLWVFDLSTNEWTRLGSLPS 49
PHA03098 PHA03098
kelch-like protein; Provisional
 251-371 5.81e-04

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 42.06  E-value: 5.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 251 IYILGGGTSwTAYSLNKIHAYNLETNAWEEIAtkpheKIGFPaaRRCHSCVQIKNDVFICGGYNGEVILGDIWKLNLQTF 330
Cdd:PHA03098 297 IYFIGGMNK-NNLSVNSVVSYDTKTKSWNKVP-----ELIYP--RKNPGVTVFNNRIYVIGGIYNSISLNTVESWKPGES 368

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 966935648 331 QWVKLPaTMPEPVYFHCAAVTpAGCMYIHGGVVNIHENKRT 371
Cdd:PHA03098 369 KWREEP-PLIFPRYNPCVVNV-NNLIYVIGGISKNDELLKT 407
Kelch_6 pfam13964
Kelch motif;
188-226 7.43e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 37.31  E-value: 7.43e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 966935648  188 GQAMAIINGSLYVFGGTTGY-IYSTDLHKLDLNTREWTQL 226
Cdd:pfam13964   4 FHSVVSVGGYIYVFGGYTNAsPALNKLEVYNPLTKSWEEL 43
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 68-96 9.99e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 36.77  E-value: 9.99e-04
                          10        20
                  ....*....|....*....|....*....
gi 966935648   68 PPARSGHRCVADNTNLYVFGGYNPDYDES 96
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQP 29
PLN02153 PLN02153
epithiospecifier protein
 68-282 1.19e-03

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 40.74  E-value: 1.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  68 PPARS--GHRCVADNTNLYVFGGYNPDYDESggpDNEDYPLFRELWRyhFATGVWHQMGtdgymPRELASMSLVLHGNNL 145
Cdd:PLN02153  71 VPRISclGVRMVAVGTKLYIFGGRDEKREFS---DFYSYDTVKNEWT--FLTKLDEEGG-----PEARTFHSMASDENHV 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648 146 LVFGGT---GIPFGESNGNDVHVCNVKYKRWALLSCRGKKPSRIYGQAMAIINGSLYVF---------GGTTGYiYSTDL 213
Cdd:PLN02153 141 YVFGGVskgGLMKTPERFRTIEAYNIADGKWVQLPDPGENFEKRGGAGFAVVQGKIWVVygfatsilpGGKSDY-ESNAV 219

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966935648 214 HKLDLNTREWTQLKPNNLScdlPEERYRHEIAHDGQRIYILGG-------GTSWTAYSLNKIHAYNLETNAWEEIA 282
Cdd:PLN02153 220 QFFDPASGKWTEVETTGAK---PSARSVFAHAVVGKYIIIFGGevwpdlkGHLGPGTLSNEGYALDTETLVWEKLG 292
PLN02193 PLN02193
nitrile-specifier protein
 62-203 1.28e-03

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 40.71  E-value: 1.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  62 TSCHRPPPARSGHRCVADNTNLYVFGGYNPDydesggpdnedyPLFRELWRYHFATGVWHQMGT--DGYMPRELASMSlV 139
Cdd:PLN02193 260 TPVEEGPTPRSFHSMAADEENVYVFGGVSAT------------ARLKTLDSYNIVDKKWFHCSTpgDSFSIRGGAGLE-V 326

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966935648 140 LHGNNLLVFGgtgipFGESNGNDVHVCNVKYKRWALLSCRGKKPSRIYGQAMAIINGSLYVFGG 203
Cdd:PLN02193 327 VQGKVWVVYG-----FNGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASAAVGKHIVIFGG 385
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 70-125 3.46e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 35.28  E-value: 3.46e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 966935648   70 ARSGHRCVADNTNLYVFGGYNPDydesggpdnedyPLFRELWRYHFATGVWHQMGT 125
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGN------------QSLNSVEVYDPETNTWSKLPS 44
Kelch_2 pfam07646
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 187-228 5.88e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 462220 [Multi-domain]  Cd Length: 47  Bit Score: 34.62  E-value: 5.88e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 966935648  187 YGQAMAIINGSLYVFGGTTGY--IYSTDLHKLDLNTREWTQLKP 228
Cdd:pfam07646   3 YPHASSVPGGKLYVVGGSDGLgdLSSSDVLVYDPETNVWTEVPR 46
PRK14131 PRK14131
N-acetylneuraminate epimerase;
66-150 8.08e-03

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 38.07  E-value: 8.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966935648  66 RPPPARSGHRCVA-DNTNLYVFGGYN--------PDYDESGGPDN--------------EDYPLFRELWRYHFATGVWHQ 122
Cdd:PRK14131 124 RSPVGLAGHVAVSlHNGKAYITGGVNknifdgyfEDLAAAGKDKTpkdkindayfdkkpEDYFFNKEVLSYDPSTNQWKN 203

                         90       100
                 ....*....|....*....|....*...
gi 966935648 123 MGTDGYMPRelASMSLVLHGNNLLVFGG 150
Cdd:PRK14131 204 AGESPFLGT--AGSAVVIKGNKLWLING 229
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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