|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
760-985 |
5.14e-64 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
:
Pssm-ID: 397130 Cd Length: 203 Bit Score: 216.46 E-value: 5.14e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 760 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 839
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 840 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 919
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966928334 920 VKLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLR 985
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELR 200
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1437-1569 |
1.15e-57 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
:
Pssm-ID: 211397 Cd Length: 134 Bit Score: 195.20 E-value: 1.15e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1437 LPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIASNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC- 1515
Cdd:cd11559 1 LPLLRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLDd 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 966928334 1516 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1569
Cdd:cd11559 81 DEQLQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1241-1353 |
4.50e-37 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
:
Pssm-ID: 397128 Cd Length: 113 Bit Score: 135.48 E-value: 4.50e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1241 LEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYE 1320
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 966928334 1321 ILELAEDMEIDIPHVWLYLAELVTPILQEGGVP 1353
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| PRK07003 super family |
cl35530 |
DNA polymerase III subunit gamma/tau; |
276-562 |
1.02e-05 |
|
DNA polymerase III subunit gamma/tau;
The actual alignment was detected with superfamily member PRK07003:
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 50.23 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 276 SEPNLAVLSIPGDTMATIQMSVEE------STPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAST 349
Cdd:PRK07003 336 GELGLAPDEYAGFTMTLLRMLAFEpavtggGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAA 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 350 PLASHTVEIHEPNGMVPSEDLEPEVESSPElalPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVS--------EP 421
Cdd:PRK07003 416 AAAAATRAEAPPAAPAPPATADRGDDAADG---DAPVPAKANARASADSRCDERDAQPPADSGSASAPASdappdaafEP 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 422 EEQAKEVTASVAPATILSATPAMAPSATSPAQEEEMEEEEEEEEEGEAGEAESEKGGEELL----------------PSE 485
Cdd:PRK07003 493 APRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALdvlrnagmrvssdrgaRAA 572
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966928334 486 STPVPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVP 562
Cdd:PRK07003 573 AAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPPPWEDIPPDDYVPLSADEGFGGP 649
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
4-356 |
4.87e-03 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 4.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 4 APQSTGPPPAPSPGLPqPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPGPAAHVYPA 83
Cdd:PHA03247 2759 RPPTTAGPPAPAPPAA-PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 84 GSQVMMIPSQISYPAsqGAYYIPGqGRSTYVVPTQQYPVQPGAPGFYPG---ASPTEFGTYAGAYYPAQGVQQFPTGVAP 160
Cdd:PHA03247 2838 APPPPPGPPPPSLPL--GGSVAPG-GDVRRRPPSRSPAAKPAAPARPPVrrlARPAVSRSTESFALPPDQPERPPQPQAP 2914
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 161 APVLMNQPPQIAPKRERKtirirDPNQGGKDiteeimsgartasTPTPPQTGGGLEPQANGETPQV---AVIVRPDDRSQ 237
Cdd:PHA03247 2915 PPPQPQPQPPPPPQPQPP-----PPPPPRPQ-------------PPLAPTTDPAGAGEPSGAVPQPwlgALVPGRVAVPR 2976
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 238 GAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVL------EPGSEPNLAVLSIPGDTMATIQMSVEESTPISRETGEPY 311
Cdd:PHA03247 2977 FRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLalheetDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEALD 3056
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 966928334 312 RLSPEPT--PLAEPILEVEVTLSKPVPESEFSSSPLQASTPLASHTV 356
Cdd:PHA03247 3057 PLPPEPHdpFAHEPDPATPEAGARESPSSQFGPPPLSANAALSRRYV 3103
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
760-985 |
5.14e-64 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 216.46 E-value: 5.14e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 760 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 839
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 840 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 919
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966928334 920 VKLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLR 985
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELR 200
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1437-1569 |
1.15e-57 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
Pssm-ID: 211397 Cd Length: 134 Bit Score: 195.20 E-value: 1.15e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1437 LPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIASNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC- 1515
Cdd:cd11559 1 LPLLRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLDd 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 966928334 1516 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1569
Cdd:cd11559 81 DEQLQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
761-988 |
1.78e-53 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 186.03 E-value: 1.78e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 761 RRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlKVPttekptvtvNFRK 840
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKNLRKYILELIFEKAVEEPNFIPAYARLCALLNA-KNP---------DFGS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 841 LLLNRCQKEFEKDkdddevfekkqkemdeaataeergrlkeeLEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVV 920
Cdd:smart00543 72 LLLERLQEEFEKG-----------------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLK 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966928334 921 KLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKT---SSRIRFMLQDVLDLRGSN 988
Cdd:smart00543 123 ELLNDLtkldpprSDFSVECLLSLLPTCGKDLEREKSPKLLDEILERLQDYLLKKDKtelSSRLRFMLELLIELRKNK 200
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1241-1353 |
4.50e-37 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 135.48 E-value: 4.50e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1241 LEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYE 1320
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 966928334 1321 ILELAEDMEIDIPHVWLYLAELVTPILQEGGVP 1353
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
1241-1353 |
4.54e-36 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 132.75 E-value: 4.54e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1241 LEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYE 1320
Cdd:smart00544 1 LKKKIFLIIEEYLSSGDTDEAVHCLLELKLPEQHHEVVKVLLTCALEEKRTYREMYSVLLSRLCQANVISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 966928334 1321 ILELAEDMEIDIPHVWLYLAELVTPILQEGGVP 1353
Cdd:smart00544 81 LLEDIEDLELDIPNAWRNLAEFVARLISDGILP 113
|
|
| eIF5C |
smart00515 |
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
1508-1591 |
1.27e-26 |
|
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5;
Pssm-ID: 214705 Cd Length: 83 Bit Score: 104.68 E-value: 1.27e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1508 KLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqqGKGVALKSVTAFFKW 1587
Cdd:smart00515 2 PLLKFLAKDEEEQLELLYAIEEFCVELEKLGKLLPKILKSLYDADILEEEAILKWYEKAVSAE--GKKKVRKNAKPFVTW 79
|
....
gi 966928334 1588 LREA 1591
Cdd:smart00515 80 LQEA 83
|
|
| W2 |
pfam02020 |
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
1520-1596 |
1.53e-23 |
|
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors.
Pssm-ID: 460415 Cd Length: 76 Bit Score: 95.67 E-value: 1.53e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966928334 1520 ELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqQGKGVALKSVTAFFKWLREAEEESD 1596
Cdd:pfam02020 1 QVDLLLALQEFCAKLEELLKLLLKILKALYDLDIVEEEAILKWWEDVSSAE-KGMKKVRKQAKPFVEWLEEAEEESD 76
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
276-562 |
1.02e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 50.23 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 276 SEPNLAVLSIPGDTMATIQMSVEE------STPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAST 349
Cdd:PRK07003 336 GELGLAPDEYAGFTMTLLRMLAFEpavtggGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAA 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 350 PLASHTVEIHEPNGMVPSEDLEPEVESSPElalPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVS--------EP 421
Cdd:PRK07003 416 AAAAATRAEAPPAAPAPPATADRGDDAADG---DAPVPAKANARASADSRCDERDAQPPADSGSASAPASdappdaafEP 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 422 EEQAKEVTASVAPATILSATPAMAPSATSPAQEEEMEEEEEEEEEGEAGEAESEKGGEELL----------------PSE 485
Cdd:PRK07003 493 APRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALdvlrnagmrvssdrgaRAA 572
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966928334 486 STPVPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVP 562
Cdd:PRK07003 573 AAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPPPWEDIPPDDYVPLSADEGFGGP 649
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
140-451 |
3.36e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 41.87 E-value: 3.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 140 TYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDiTEEIMSGARTA--STPTPPQTGGGLEP 217
Cdd:pfam17823 116 AAAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAAASA-PHAASPAPRTAasSTTAASSTTAASSA 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 218 QANGETPQVAVIVRPDDRSQGAIIADRPGLpGPEHSPSESQPSSPSPTPSPSPVLEPGSepnLAVLSIPGDTMATIQMSV 297
Cdd:pfam17823 195 PTTAASSAPATLTPARGISTAATATGHPAA-GTALAAVGNSSPAAGTVTAAVGTVTPAA---LATLAAAAGTVASAAGTI 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 298 EESTPISRetgepyRLSPeptplaepilevevtlSKPVPESEFSSSPLQASTPLASHTVeihepngMVPSEDlEPEVESS 377
Cdd:pfam17823 271 NMGDPHAR------RLSP----------------AKHMPSDTMARNPAAPMGAQAQGPI-------IQVSTD-QPVHNTA 320
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966928334 378 PElalppacpsESPVPIAPTAQPeellNGAPSPPAVDLSPVSEPEEQAKEVTASVAPATILSATPAMapSATSP 451
Cdd:pfam17823 321 GE---------PTPSPSNTTLEP----NTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSMIPEV--EATSP 379
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
4-356 |
4.87e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 4.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 4 APQSTGPPPAPSPGLPqPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPGPAAHVYPA 83
Cdd:PHA03247 2759 RPPTTAGPPAPAPPAA-PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 84 GSQVMMIPSQISYPAsqGAYYIPGqGRSTYVVPTQQYPVQPGAPGFYPG---ASPTEFGTYAGAYYPAQGVQQFPTGVAP 160
Cdd:PHA03247 2838 APPPPPGPPPPSLPL--GGSVAPG-GDVRRRPPSRSPAAKPAAPARPPVrrlARPAVSRSTESFALPPDQPERPPQPQAP 2914
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 161 APVLMNQPPQIAPKRERKtirirDPNQGGKDiteeimsgartasTPTPPQTGGGLEPQANGETPQV---AVIVRPDDRSQ 237
Cdd:PHA03247 2915 PPPQPQPQPPPPPQPQPP-----PPPPPRPQ-------------PPLAPTTDPAGAGEPSGAVPQPwlgALVPGRVAVPR 2976
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 238 GAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVL------EPGSEPNLAVLSIPGDTMATIQMSVEESTPISRETGEPY 311
Cdd:PHA03247 2977 FRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLalheetDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEALD 3056
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 966928334 312 RLSPEPT--PLAEPILEVEVTLSKPVPESEFSSSPLQASTPLASHTV 356
Cdd:PHA03247 3057 PLPPEPHdpFAHEPDPATPEAGARESPSSQFGPPPLSANAALSRRYV 3103
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
760-985 |
5.14e-64 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 216.46 E-value: 5.14e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 760 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 839
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 840 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 919
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966928334 920 VKLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLR 985
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELR 200
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1437-1569 |
1.15e-57 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
Pssm-ID: 211397 Cd Length: 134 Bit Score: 195.20 E-value: 1.15e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1437 LPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIASNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC- 1515
Cdd:cd11559 1 LPLLRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLDd 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 966928334 1516 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1569
Cdd:cd11559 81 DEQLQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
761-988 |
1.78e-53 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 186.03 E-value: 1.78e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 761 RRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlKVPttekptvtvNFRK 840
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKNLRKYILELIFEKAVEEPNFIPAYARLCALLNA-KNP---------DFGS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 841 LLLNRCQKEFEKDkdddevfekkqkemdeaataeergrlkeeLEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVV 920
Cdd:smart00543 72 LLLERLQEEFEKG-----------------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLK 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966928334 921 KLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKT---SSRIRFMLQDVLDLRGSN 988
Cdd:smart00543 123 ELLNDLtkldpprSDFSVECLLSLLPTCGKDLEREKSPKLLDEILERLQDYLLKKDKtelSSRLRFMLELLIELRKNK 200
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1241-1353 |
4.50e-37 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 135.48 E-value: 4.50e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1241 LEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYE 1320
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 966928334 1321 ILELAEDMEIDIPHVWLYLAELVTPILQEGGVP 1353
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
1241-1353 |
4.54e-36 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 132.75 E-value: 4.54e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1241 LEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYE 1320
Cdd:smart00544 1 LKKKIFLIIEEYLSSGDTDEAVHCLLELKLPEQHHEVVKVLLTCALEEKRTYREMYSVLLSRLCQANVISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 966928334 1321 ILELAEDMEIDIPHVWLYLAELVTPILQEGGVP 1353
Cdd:smart00544 81 LLEDIEDLELDIPNAWRNLAEFVARLISDGILP 113
|
|
| eIF5C |
smart00515 |
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
1508-1591 |
1.27e-26 |
|
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5;
Pssm-ID: 214705 Cd Length: 83 Bit Score: 104.68 E-value: 1.27e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1508 KLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqqGKGVALKSVTAFFKW 1587
Cdd:smart00515 2 PLLKFLAKDEEEQLELLYAIEEFCVELEKLGKLLPKILKSLYDADILEEEAILKWYEKAVSAE--GKKKVRKNAKPFVTW 79
|
....
gi 966928334 1588 LREA 1591
Cdd:smart00515 80 LQEA 83
|
|
| W2 |
pfam02020 |
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
1520-1596 |
1.53e-23 |
|
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors.
Pssm-ID: 460415 Cd Length: 76 Bit Score: 95.67 E-value: 1.53e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966928334 1520 ELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqQGKGVALKSVTAFFKWLREAEEESD 1596
Cdd:pfam02020 1 QVDLLLALQEFCAKLEELLKLLLKILKALYDLDIVEEEAILKWWEDVSSAE-KGMKKVRKQAKPFVEWLEEAEEESD 76
|
|
| W2 |
cd11473 |
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of ... |
1438-1563 |
3.68e-23 |
|
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of several translation initiation factors, including the epsilon chain of eIF2b, where it has been found to catalyze the conversion of eIF2.GDP to its active eIF2.GTP form. The structure of the domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211395 Cd Length: 135 Bit Score: 96.78 E-value: 3.68e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1438 PSEELNRQLEKLLKEG-SSNQRVFDWIEANLSEQQIASNTLVRALMTAVCYSAIIFE----TPLRVDVAVLKARAKLLQK 1512
Cdd:cd11473 2 KNKKLRDSLLKELEEDkSSDVESVKAAKSKLDLDPISLEEVVKVLLTAVVNAVESADsislTQKEQLVLVLKKYGPVLRE 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 966928334 1513 YLCD-EQKELQALYALQALVVT--LEQPPNLLRMFFDALYDEDVVKEDAFYSWE 1563
Cdd:cd11473 82 LLKLiKKDQLYLLLKIEKLCLQlkLSELISLLEKILDLLYDADVLSEEAILSWF 135
|
|
| W2_eIF2B_epsilon |
cd11558 |
C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a ... |
1466-1596 |
1.34e-15 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a heteropentameric complex which functions as a guanine nucleotide exchange factor in the recycling of eIF-2 during the initiation of translation in eukaryotes. The epsilon and gamma subunits are sequence similar and both are essential in yeast. Epsilon appears to be the catalytically active subunit, with gamma enhancing its activity. The C-terminal domain of the eIF2B epsilon subunit contains bipartite motifs rich in acidic and aromatic residues, which are responsible for the interaction with eIF2. The structure of the domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211396 Cd Length: 169 Bit Score: 76.14 E-value: 1.34e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1466 NLSEQQIASNTlVRALMTAVCYSAIIFETPLRVDVAVLKARAK-LLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMF 1544
Cdd:cd11558 39 NVTDHDVRRAV-VKALLELILEVSSTSTAELLEALKKLLSKWGpLLENYVKSQDDQVELLLALEEFCLESEEGGPLFAKL 117
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 966928334 1545 FDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESD 1596
Cdd:cd11558 118 LHALYDLDILEEEAILEWWEEPDAGADEEMKKVRELVKKFIEWLEEAEEESD 169
|
|
| W2_eIF5 |
cd11561 |
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase ... |
1438-1596 |
2.04e-09 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase acceleration protein (GAP), as well as a GDP dissociation inhibitor (GDI) during translational initiation in eukaryotes. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211399 Cd Length: 157 Bit Score: 58.01 E-value: 2.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1438 PSEELNR--QLEKLLKEGSSNQRVFDwIEANLSEQQIASNTLVRALmtavcysAIIFETPLRVD-VAVLKARAKLLQKYL 1514
Cdd:cd11561 1 EEEEDERvdELGEFLKKNKDESGLSE-LKEILKEAERLDVVKDKAV-------LVLAEVLFDENiVKEIKKRKALLLKLV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1515 CDEQKELQALYALQALVVtlEQPPNLLRMF---FDALYDEDVVKEDAFYSW---ESSKDPAEQQGKGVaLKSVTAFFKWL 1588
Cdd:cd11561 73 TDEKAQKALLGGIERFCG--KHSPELLKKVpliLKALYDNDILEEEVILKWyekVSKKYVSKEKSKKV-RKAAEPFVEWL 149
|
....*...
gi 966928334 1589 REAEEESD 1596
Cdd:cd11561 150 EEAEEEEE 157
|
|
| W2_eIF5C_like |
cd11560 |
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; ... |
1434-1594 |
6.99e-08 |
|
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; eIF5C appears to be essential for the initiation of protein translation; its actual function, and specifically that of the C-terminal W2 domain, are not well understood. The Drosophila ortholog, kra (krasavietz) or exba (extra bases), may be involved in translational inhibition in neural development. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211398 [Multi-domain] Cd Length: 194 Bit Score: 54.53 E-value: 6.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1434 QRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIASN--------TLVRALMTAVCYSA---IIFETPLRVdvav 1502
Cdd:cd11560 29 YRKQASQEIKKELQQELKEMIAEEEPVKEIIAAVKEQMKKSSlpehevvgLLWTALMDAVEWSKkedQIAEQALRH---- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 1503 LKARAKLLQKYLCDEQKELQALYALQalVVTLEQPpNLLRMFFD---ALYDEDVVKEDAFYSWEssKDPAEQQGKGVALK 1579
Cdd:cd11560 105 LKKYAPLLAAFCTTARAELALLNKIQ--EYCYENM-KFMKVFQKivkLLYKADVLSEDAILKWY--KKGHSPKGKQVFLK 179
|
170
....*....|....*
gi 966928334 1580 SVTAFFKWLREAEEE 1594
Cdd:cd11560 180 QMEPFVEWLQEAEEE 194
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
276-562 |
1.02e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 50.23 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 276 SEPNLAVLSIPGDTMATIQMSVEE------STPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAST 349
Cdd:PRK07003 336 GELGLAPDEYAGFTMTLLRMLAFEpavtggGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAA 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 350 PLASHTVEIHEPNGMVPSEDLEPEVESSPElalPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVS--------EP 421
Cdd:PRK07003 416 AAAAATRAEAPPAAPAPPATADRGDDAADG---DAPVPAKANARASADSRCDERDAQPPADSGSASAPASdappdaafEP 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 422 EEQAKEVTASVAPATILSATPAMAPSATSPAQEEEMEEEEEEEEEGEAGEAESEKGGEELL----------------PSE 485
Cdd:PRK07003 493 APRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALdvlrnagmrvssdrgaRAA 572
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966928334 486 STPVPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVP 562
Cdd:PRK07003 573 AAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPPPWEDIPPDDYVPLSADEGFGGP 649
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
17-563 |
3.36e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 45.70 E-value: 3.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 17 GLPQPAFPPGQTAPVVfSTPQAT----------QMNTPSQPRQHFYPSRAQPPSSAAsrvqsaaparpgpaahvyPAGSQ 86
Cdd:PHA03247 2562 AAPDRSVPPPRPAPRP-SEPAVTsrarrpdappQSARPRAPVDDRGDPRGPAPPSPL------------------PPDTH 2622
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 87 VMMIPSqisyPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQ--FPTGVAPAPVL 164
Cdd:PHA03247 2623 APDPPP----PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRraARPTVGSLTSL 2698
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 165 MNQPPQIAPKRERktirirdPNQGGKDITEEIMSGARTASTPTPPQTGGglePQANGETPQVAVIVRPDDRSQGAIIADR 244
Cdd:PHA03247 2699 ADPPPPPPTPEPA-------PHALVSATPLPPGPAAARQASPALPAAPA---PPAVPAGPATPGGPARPARPPTTAGPPA 2768
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 245 PGLP----GPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMATIQMSVEESTPISRETGEPYRLSPEPTPL 320
Cdd:PHA03247 2769 PAPPaapaAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPP 2848
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 321 AEPiLEVEVTLSKPV----PESEFSSSPLQASTPLASHTVE--IHEPNGMVPSEDLEPEVESSPELALPPACPSESPVPI 394
Cdd:PHA03247 2849 SLP-LGGSVAPGGDVrrrpPSRSPAAKPAAPARPPVRRLARpaVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPP 2927
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 395 APTAQPE-ELLNGAPSPPAVDLSPVSEPEEQAKEV-TASVAP---ATILSATPAMAPSATSPAQEEEMEEEEEEEEEGEA 469
Cdd:PHA03247 2928 QPQPPPPpPPRPQPPLAPTTDPAGAGEPSGAVPQPwLGALVPgrvAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSW 3007
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 470 GEAESekggeelLPSESTPVPANLSQNL------EAAAATQVAVSVPKRrrkikelNKKEAVgDLLDAFKEANPAVPEVE 543
Cdd:PHA03247 3008 ASSLA-------LHEETDPPPVSLKQTLwppddtEDSDADSLFDSDSER-------SDLEAL-DPLPPEPHDPFAHEPDP 3072
|
570 580
....*....|....*....|
gi 966928334 544 NQPPAGSNPGPESEgSGVPP 563
Cdd:PHA03247 3073 ATPEAGARESPSSQ-FGPPP 3091
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
84-571 |
4.01e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 45.31 E-value: 4.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 84 GSQVMMIPSQISYPASQGAYYIPGQGRStyvvPTQQYPVQPG--APGFYPGASPTEfgtyagAYYP-----AQGVQQFPT 156
Cdd:PHA03247 2476 GAPVYRRPAEARFPFAAGAAPDPGGGGP----PDPDAPPAPSrlAPAILPDEPVGE------PVHPrmltwIRGLEELAS 2545
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 157 GVA--PAPVLMNQPPQIAPKRERKTIRIRdPNQGGKDITeeimsgARTASTPTPPQtggglepQANGETPQvavivrpDD 234
Cdd:PHA03247 2546 DDAgdPPPPLPPAAPPAAPDRSVPPPRPA-PRPSEPAVT------SRARRPDAPPQ-------SARPRAPV-------DD 2604
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 235 RSqgaiiaDRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMATIQMSVEESTPISRETGEPYRLS 314
Cdd:PHA03247 2605 RG------DPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASS 2678
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 315 P--EPTPLAEPILEVEVTLSK----PVPESEFSSSPLQASTPLASHTVEIHEPNGMVPSEDLEPEVESSPELALPPACPS 388
Cdd:PHA03247 2679 PpqRPRRRAARPTVGSLTSLAdpppPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPA 2758
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 389 ESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASVAPATilSATPAMAPSATSPAQEEEMEEEEEEEEEGE 468
Cdd:PHA03247 2759 RPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPAD--PPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 469 AGEAESEKGGEELLPSESTPVPANlsqNLEAAAATQVAVSVPKRRRKIKELN-KKEAVGDLLDAFKEAnPAVPEVENQPP 547
Cdd:PHA03247 2837 TAPPPPPGPPPPSLPLGGSVAPGG---DVRRRPPSRSPAAKPAAPARPPVRRlARPAVSRSTESFALP-PDQPERPPQPQ 2912
|
490 500
....*....|....*....|....
gi 966928334 548 AGSNPGPESEGSgVPPRPEEADET 571
Cdd:PHA03247 2913 APPPPQPQPQPP-PPPQPQPPPPP 2935
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
300-453 |
7.56e-04 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 44.26 E-value: 7.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 300 STPISR-ETGEPYRLSPEPTPLAEPILeVEVTLSKPVPESEfSSSPLQASTPLASHTVEIHEPN--GMVPSEDLEPEVES 376
Cdd:PRK10811 844 RYPVVRpQDVQVEEQREAEEVQVQPVV-AEVPVAAAVEPVV-SAPVVEAVAEVVEEPVVVAEPQpeEVVVVETTHPEVIA 921
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 377 SPELALPP-------ACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASVAPATILSATPAMAPSAT 449
Cdd:PRK10811 922 APVTEQPQvitesdvAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEV 1001
|
....
gi 966928334 450 SPAQ 453
Cdd:PRK10811 1002 APAQ 1005
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
405-571 |
9.15e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.10 E-value: 9.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 405 NGAPSPPAVDLSPVSEPEEQAKEVTASVAPATILSATPAMAPS----ATSPAQEEEMEEEEEEEEEGEAGEAESEKGGEE 480
Cdd:PRK12323 369 GGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAaaaaARAVAAAPARRSPAPEALAAARQASARGPGGAP 448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 481 LLPSESTPVPANLSQNLEAAAATQVAVSVPKRRRKIKElNKKEAVGDLLDAFKEANPAVPEVenqPPAGSNPGPESEGSG 560
Cdd:PRK12323 449 APAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPA-AAPAPADDDPPPWEELPPEFASP---APAQPDAAPAGWVAE 524
|
170
....*....|.
gi 966928334 561 VPPRPEEADET 571
Cdd:PRK12323 525 SIPDPATADPD 535
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
184-448 |
2.73e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 42.76 E-value: 2.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 184 DPNQGGKDITEEIMSGARTAS------------TPTPPQTGgglePQANGETPQVAVIVRPDDRSQGAIIADRP------ 245
Cdd:PRK10263 308 DPLLNGAPITEPVAVAAAATTatqswaapvepvTQTPPVAS----VDVPPAQPTVAWQPVPGPQTGEPVIAPAPegypqq 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 246 ---GLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMATIQMSVEESTPISRETGEPyrlsPEPTPLAE 322
Cdd:PRK10263 384 sqyAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEE----QQSTFAPQ 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 323 PILEVEVTLSKPVPESEFSSSPLQASTPLASHTV-EIHEPNGMVPSEDLEPEVESS-----PELAL---PPACPSESPVP 393
Cdd:PRK10263 460 STYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEpVVEETKPARPPLYYFEEVEEKrarerEQLAAwyqPIPEPVKEPEP 539
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 966928334 394 IAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAkevtASVAPATILSATPAMAPSA 448
Cdd:PRK10263 540 IKSSLKAPSVAAVPPVEAAAAVSPLASGVKKA----TLATGAAATVAAPVFSLAN 590
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
140-451 |
3.36e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 41.87 E-value: 3.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 140 TYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDiTEEIMSGARTA--STPTPPQTGGGLEP 217
Cdd:pfam17823 116 AAAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAAASA-PHAASPAPRTAasSTTAASSTTAASSA 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 218 QANGETPQVAVIVRPDDRSQGAIIADRPGLpGPEHSPSESQPSSPSPTPSPSPVLEPGSepnLAVLSIPGDTMATIQMSV 297
Cdd:pfam17823 195 PTTAASSAPATLTPARGISTAATATGHPAA-GTALAAVGNSSPAAGTVTAAVGTVTPAA---LATLAAAAGTVASAAGTI 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 298 EESTPISRetgepyRLSPeptplaepilevevtlSKPVPESEFSSSPLQASTPLASHTVeihepngMVPSEDlEPEVESS 377
Cdd:pfam17823 271 NMGDPHAR------RLSP----------------AKHMPSDTMARNPAAPMGAQAQGPI-------IQVSTD-QPVHNTA 320
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966928334 378 PElalppacpsESPVPIAPTAQPeellNGAPSPPAVDLSPVSEPEEQAKEVTASVAPATILSATPAMapSATSP 451
Cdd:pfam17823 321 GE---------PTPSPSNTTLEP----NTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSMIPEV--EATSP 379
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
4-356 |
4.87e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 4.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 4 APQSTGPPPAPSPGLPqPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPGPAAHVYPA 83
Cdd:PHA03247 2759 RPPTTAGPPAPAPPAA-PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 84 GSQVMMIPSQISYPAsqGAYYIPGqGRSTYVVPTQQYPVQPGAPGFYPG---ASPTEFGTYAGAYYPAQGVQQFPTGVAP 160
Cdd:PHA03247 2838 APPPPPGPPPPSLPL--GGSVAPG-GDVRRRPPSRSPAAKPAAPARPPVrrlARPAVSRSTESFALPPDQPERPPQPQAP 2914
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 161 APVLMNQPPQIAPKRERKtirirDPNQGGKDiteeimsgartasTPTPPQTGGGLEPQANGETPQV---AVIVRPDDRSQ 237
Cdd:PHA03247 2915 PPPQPQPQPPPPPQPQPP-----PPPPPRPQ-------------PPLAPTTDPAGAGEPSGAVPQPwlgALVPGRVAVPR 2976
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 238 GAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVL------EPGSEPNLAVLSIPGDTMATIQMSVEESTPISRETGEPY 311
Cdd:PHA03247 2977 FRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLalheetDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEALD 3056
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 966928334 312 RLSPEPT--PLAEPILEVEVTLSKPVPESEFSSSPLQASTPLASHTV 356
Cdd:PHA03247 3057 PLPPEPHdpFAHEPDPATPEAGARESPSSQFGPPPLSANAALSRRYV 3103
|
|
| TALPID3 |
pfam15324 |
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ... |
287-422 |
5.56e-03 |
|
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.
Pssm-ID: 434634 [Multi-domain] Cd Length: 1288 Bit Score: 41.41 E-value: 5.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 287 GDTMATIQMSVEESTPISRETGEPYRLSPEPTPLAEPilevevTLSKPVPESEfsssPLQASTPLASHTVEIHEpngMVP 366
Cdd:pfam15324 959 GDREAQREPPVAASVPGDLPTKETLLPTPVPTPQPTP------PCSPPSPLKE----PSPVKTPDSSPCVSEHD---FFP 1025
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 966928334 367 SEDLEPEVESSPELALPPA-CPSESPVPIAPTAqpeellnGAPSPP----AVDLSPVSEPE 422
Cdd:pfam15324 1026 VKEIPPEKGADTGPAVSLViTPTVTPIATPPPA-------ATPTPPlsenSIDKLKSPSPE 1079
|
|
| PHA03325 |
PHA03325 |
nuclear-egress-membrane-like protein; Provisional |
291-451 |
6.01e-03 |
|
nuclear-egress-membrane-like protein; Provisional
Pssm-ID: 223044 Cd Length: 418 Bit Score: 41.02 E-value: 6.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 291 ATIQMSVEESTPISRETG-EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQASTplashtveihepnGMVPSED 369
Cdd:PHA03325 262 FMLNSSLPTSAPKRRSRRaGAMRAAAGETADLADDDGSEHSDPEPLPASLPPPPVRRPRV-------------KHPEAGK 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966928334 370 LEPEVESSPElALPPACPSESP-VPIAPTAQPEEllnGAPSPPAVDLSPVSEPEEQAKEVTASVAPATILSATPaMAPSA 448
Cdd:PHA03325 329 EEPDGARNAE-AKEPAQPATSTsSKGSSSAQNKD---SGSTGPGSSLAAASSFLEDDDFGSPPLDLTTSLRHMP-SPSVT 403
|
...
gi 966928334 449 TSP 451
Cdd:PHA03325 404 SAP 406
|
|
| |
