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Conserved domains on  [gi|1622909132|ref|XP_014985471|]
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golgin subfamily B member 1 isoform X6 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1870-2742 2.79e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.28  E-value: 2.79e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1870 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1939
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1940 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2012
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2013 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD---------DTQSEAARVLADNLK------------LK 2071
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEeleaeleelESRLEELEEQLETLRskvaqlelqiasLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2072 KELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2151
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2152 TVAQLAAFTKSMSSLQDDRDRV------IDEAKKWERKFSDAIQTKEEEIRLKE--ENCSVLKDQLRQMSIHMEELKINI 2223
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLegfsegVKALLKNQSGLSGILGVLSELISVDEgyEAAIEAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2224 SRLEHDKQIWESKAqTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQL---TDLSNSLEKC 2300
Cdd:TIGR02168  560 KAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2301 KeqKENLEGIIRQQEADIQNSKFSYEQletdlQASRELTSRLHEEINMKEqkmislLSGKEEAIQVAIAELRQQHDKEIK 2380
Cdd:TIGR02168  639 K--KLRPGYRIVTLDGDLVRPGGVITG-----GSAKTNSSILERRREIEE------LEEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2381 ELENLLSQEEeenivleeenkkavdktnqlmetlnaikkeniQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsvI 2460
Cdd:TIGR02168  706 ELEELEEELE--------------------------------QLRKELEELSRQISALRKDLARLEAEVEQLEER----I 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2461 LEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleaqlqqnKELKNKYAK 2540
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAAN 821

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2541 LEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyhaqLKVKEEELQRLSALLSSS 2620
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALL 892

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2621 QKRITELEEELvcvqKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENK 2696
Cdd:TIGR02168  893 RSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEE 968

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*.
gi 1622909132 2697 DLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2742
Cdd:TIGR02168  969 EARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1271-2056 6.61e-19

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 95.13  E-value: 6.61e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1271 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGL-EIESLKTASHEAEVRAESLQQKLESSQLQ 1349
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1350 iaglehLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1426
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1427 QVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARDTIEHLTKSLADVESH 1495
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1496 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEG-------LTEDKEKLVKEIESLKSSKIA 1568
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqLGSVGERYATAIEVAAGNRLN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1569 ----ESSEWQEKHKELQKEYEILLQSYENVsNEAERIQHVVEAVRQEKQELYGklrsteANKKETEKQLQEAEKEMEEMK 1644
Cdd:TIGR02169  551 nvvvEDDAVAKEAIELLKRRKAGRATFLPL-NKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1645 EKMRKFAKSKQQ--KILELEEENDRLRAEVHPAGGTAKECMETLLSsnASMKEEVERVKMEYETLSKKFQSLMSEKDSLS 1722
Cdd:TIGR02169  624 LVVEDIEAARRLmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFS--RSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1723 EEVQDLKHQLESnvsKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSlsmstrpacsesvpsensanpavsedvSSHD 1802
Cdd:TIGR02169  702 NRLDELSQELSD---ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS---------------------------SLEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1803 EINNYLQQIDQLKERIAGLEEEKQKNKEfsQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE 1882
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEE--ALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1883 TAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1962
Cdd:TIGR02169  830 YLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1963 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR-------------YQEKISALERTVKALEFVQTESQKDLEITK 2029
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelsledVQAELQRVEEEIRALEPVNMLAIQEYEEVL 985

                          810       820
                   ....*....|....*....|....*..
gi 1622909132 2030 ENLAQAVEHRKKAQAELASFKVLLDDT 2056
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 727-1615 3.51e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 3.51e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  727 VVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLsieakskdvkievlQNELDDVQLQFSEQSTLIRSLQ 806
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL--------------REELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  807 SQLQNKESEvlegaervrhisskveelsqaLSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQL 886
Cdd:TIGR02168  260 AELQELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  887 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAglisKEELQHEFDLLKKENEQRKRKLQA 966
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  967 ALINRKELLQRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIR 1046
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1047 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASdgdsvALVKETVVISPPGTDSGEH 1126
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK-----ALLKNQSGLSGILGVLSEL 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1127 WKPElEEKILALEKEkeqLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIG 1199
Cdd:TIGR02168  529 ISVD-EGYEAAIEAA---LGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1200 DQLRQLQIQVRESIDGKLPSpdqqewCSPTPGLEEplfkATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQ 1275
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLGG------VLVVDDLDN----ALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILE 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1276 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEH 1355
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1356 lrelqpELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHderiKQLQVELCEMKQ 1435
Cdd:TIGR02168  755 ------ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL----TLLNEEAANLRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1436 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEhltkslADVESHVsaqnKEKDRVLGRLALLQE 1515
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE------SELEALL----NERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1516 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEssewqekhkELQKEYEILLQSYENVS 1595
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIE 964

                          890       900
                   ....*....|....*....|
gi 1622909132 1596 NEAERIQHVVEAVRQEKQEL 1615
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 154-988 1.76e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.02  E-value: 1.76e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  154 QQLQEKEELISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 233
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  234 EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKME---LEVAERKLSFHNLQEE 310
Cdd:TIGR02168  283 IEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEeklEELKEELESLEAELEE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  311 MRHLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQ-TI 389
Cdd:TIGR02168  363 LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQaEL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  390 EQLEDQLQQKSKEISQFLNRLPLQQHEtasqtcfpdvynegtqavteenIASLQKRVVELENEKGALLLSSIELEELKAE 469
Cdd:TIGR02168  443 EELEEELEELQEELERLEEALEELREE----------------------LEEAEQALDAAERELAQLQARLDSLERLQEN 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  470 NEKLSSQI-TLLEAQNRIGEADREVSEISIVDDANKRSSST--EESGQDVLENTFSQKHKELSVLLlemKEAQEEIAFLK 546
Cdd:TIGR02168  501 LEGFSEGVkALLKNQSGLSGILGVLSELISVDEGYEAAIEAalGGRLQAVVVENLNAAKKAIAFLK---QNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  547 LQLQGKRAEEGDHEVLdQKEMKQMEGEGIAPIKMEVFLEDTGQNFplmpneESSLPAVEKEQASTEHQNRTSEEISLNDA 626
Cdd:TIGR02168  578 LDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  627 GVELKS-----TKQDCDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNA 701
Cdd:TIGR02168  651 DGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  702 DNNSSAFTALSEERDQLLAQVKELSvvtelrAQVRQLEMNLAEAERQRrfdyesqtahhNLLTEQIHSLSIEAKSKDVKI 781
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  782 EVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETL 861
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  862 QQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspa 938
Cdd:TIGR02168  865 EELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--- 941

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622909132  939 glisKEELQHEFDLLKKENEQRKRKLQAALinrKELLQRVSRLEEELANL 988
Cdd:TIGR02168  942 ----QERLSEEYSLTLEEAEALENKIEDDE---EEARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2414-3157 1.54e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.39  E-value: 1.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2414 LNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSV---ILEKDQLIQEAAAENNKLKEEIRGLRSHMDD 2490
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELeeeIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2491 LNSENAKLDAELIQYREDLNQVISIKDSQQKQL------LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQE 2564
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2565 EKRDLSKEIESLKVSVSQLTRQVTALQEE-----------------GTLGIYHAQLKVKEEELQRLSALLSSSQKRITEL 2627
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2628 EEELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMV 2691
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2692 TKENKDLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSM 2762
Cdd:TIGR02168  554 NLNAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2763 DLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpats 2842
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEEL----------------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2843 LAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQL 2922
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2923 RMEKSSWEIHERRMKEQYLMAisDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRN 3002
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 3003 QLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNI 3082
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRR 915

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132 3083 DvapgapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSLAEEQIRRLE 3157
Cdd:TIGR02168  916 E-------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 8-258 2.02e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 2.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132    8 QEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEEKKAADNKIKKLKLHAKakltSLNKHIEEMKAQGGTVLLTEP 87
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA----RLEERRRELEERLEELEEELA 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132   88 QSEEQLSKHDKSSTEEEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMKQQLQEKEELISTLQ 167
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  168 AQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEEslvGRAQVVDLL 247
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL---LEAALAELL 483

                          250
                   ....*....|.
gi 1622909132  248 QQELTAAEQRN 258
Cdd:COG1196    484 EELAEAAARLL 494
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1870-2742 2.79e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.28  E-value: 2.79e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1870 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1939
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1940 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2012
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2013 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD---------DTQSEAARVLADNLK------------LK 2071
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEeleaeleelESRLEELEEQLETLRskvaqlelqiasLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2072 KELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2151
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2152 TVAQLAAFTKSMSSLQDDRDRV------IDEAKKWERKFSDAIQTKEEEIRLKE--ENCSVLKDQLRQMSIHMEELKINI 2223
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLegfsegVKALLKNQSGLSGILGVLSELISVDEgyEAAIEAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2224 SRLEHDKQIWESKAqTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQL---TDLSNSLEKC 2300
Cdd:TIGR02168  560 KAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2301 KeqKENLEGIIRQQEADIQNSKFSYEQletdlQASRELTSRLHEEINMKEqkmislLSGKEEAIQVAIAELRQQHDKEIK 2380
Cdd:TIGR02168  639 K--KLRPGYRIVTLDGDLVRPGGVITG-----GSAKTNSSILERRREIEE------LEEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2381 ELENLLSQEEeenivleeenkkavdktnqlmetlnaikkeniQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsvI 2460
Cdd:TIGR02168  706 ELEELEEELE--------------------------------QLRKELEELSRQISALRKDLARLEAEVEQLEER----I 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2461 LEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleaqlqqnKELKNKYAK 2540
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAAN 821

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2541 LEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyhaqLKVKEEELQRLSALLSSS 2620
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALL 892

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2621 QKRITELEEELvcvqKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENK 2696
Cdd:TIGR02168  893 RSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEE 968

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*.
gi 1622909132 2697 DLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2742
Cdd:TIGR02168  969 EARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1271-2056 6.61e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.13  E-value: 6.61e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1271 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGL-EIESLKTASHEAEVRAESLQQKLESSQLQ 1349
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1350 iaglehLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1426
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1427 QVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARDTIEHLTKSLADVESH 1495
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1496 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEG-------LTEDKEKLVKEIESLKSSKIA 1568
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqLGSVGERYATAIEVAAGNRLN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1569 ----ESSEWQEKHKELQKEYEILLQSYENVsNEAERIQHVVEAVRQEKQELYGklrsteANKKETEKQLQEAEKEMEEMK 1644
Cdd:TIGR02169  551 nvvvEDDAVAKEAIELLKRRKAGRATFLPL-NKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1645 EKMRKFAKSKQQ--KILELEEENDRLRAEVHPAGGTAKECMETLLSsnASMKEEVERVKMEYETLSKKFQSLMSEKDSLS 1722
Cdd:TIGR02169  624 LVVEDIEAARRLmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFS--RSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1723 EEVQDLKHQLESnvsKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSlsmstrpacsesvpsensanpavsedvSSHD 1802
Cdd:TIGR02169  702 NRLDELSQELSD---ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS---------------------------SLEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1803 EINNYLQQIDQLKERIAGLEEEKQKNKEfsQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE 1882
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEE--ALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1883 TAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1962
Cdd:TIGR02169  830 YLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1963 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR-------------YQEKISALERTVKALEFVQTESQKDLEITK 2029
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelsledVQAELQRVEEEIRALEPVNMLAIQEYEEVL 985

                          810       820
                   ....*....|....*....|....*..
gi 1622909132 2030 ENLAQAVEHRKKAQAELASFKVLLDDT 2056
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 727-1615 3.51e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 3.51e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  727 VVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLsieakskdvkievlQNELDDVQLQFSEQSTLIRSLQ 806
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL--------------REELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  807 SQLQNKESEvlegaervrhisskveelsqaLSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQL 886
Cdd:TIGR02168  260 AELQELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  887 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAglisKEELQHEFDLLKKENEQRKRKLQA 966
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  967 ALINRKELLQRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIR 1046
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1047 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASdgdsvALVKETVVISPPGTDSGEH 1126
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK-----ALLKNQSGLSGILGVLSEL 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1127 WKPElEEKILALEKEkeqLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIG 1199
Cdd:TIGR02168  529 ISVD-EGYEAAIEAA---LGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1200 DQLRQLQIQVRESIDGKLPSpdqqewCSPTPGLEEplfkATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQ 1275
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLGG------VLVVDDLDN----ALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILE 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1276 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEH 1355
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1356 lrelqpELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHderiKQLQVELCEMKQ 1435
Cdd:TIGR02168  755 ------ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL----TLLNEEAANLRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1436 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEhltkslADVESHVsaqnKEKDRVLGRLALLQE 1515
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE------SELEALL----NERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1516 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEssewqekhkELQKEYEILLQSYENVS 1595
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIE 964

                          890       900
                   ....*....|....*....|
gi 1622909132 1596 NEAERIQHVVEAVRQEKQEL 1615
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1275-1822 4.85e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 4.85e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1275 QIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE 1354
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1355 H-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1433
Cdd:COG1196    316 ErLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1434 KQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALL 1513
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1514 QEERDKLitemDRSLLENQSLSGSCESLKLALEGLTED-KEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYE 1592
Cdd:COG1196    476 EAALAEL----LEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1593 NVSNEAERIqhvvEAVRQEKQELYGK-----LRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDR 1667
Cdd:COG1196    552 VVEDDEVAA----AAIEYLKAAKAGRatflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1668 LRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEK 1747
Cdd:COG1196    628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909132 1748 HDNQMNVTEEATQSIpgETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLE 1822
Cdd:COG1196    708 ELAEAEEERLEEELE--EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1807-2333 5.32e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 5.32e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1807 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEE 1886
Cdd:COG1196    230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1887 EKDDLE---ERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKI 1963
Cdd:COG1196    310 RRRELEerlEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1964 QGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQ 2043
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2044 AELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALRR 2119
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2120 EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKE 2199
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2200 ENC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNS 2272
Cdd:COG1196    630 ARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909132 2273 QNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQ 2333
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 154-988 1.76e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.02  E-value: 1.76e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  154 QQLQEKEELISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 233
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  234 EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKME---LEVAERKLSFHNLQEE 310
Cdd:TIGR02168  283 IEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEeklEELKEELESLEAELEE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  311 MRHLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQ-TI 389
Cdd:TIGR02168  363 LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQaEL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  390 EQLEDQLQQKSKEISQFLNRLPLQQHEtasqtcfpdvynegtqavteenIASLQKRVVELENEKGALLLSSIELEELKAE 469
Cdd:TIGR02168  443 EELEEELEELQEELERLEEALEELREE----------------------LEEAEQALDAAERELAQLQARLDSLERLQEN 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  470 NEKLSSQI-TLLEAQNRIGEADREVSEISIVDDANKRSSST--EESGQDVLENTFSQKHKELSVLLlemKEAQEEIAFLK 546
Cdd:TIGR02168  501 LEGFSEGVkALLKNQSGLSGILGVLSELISVDEGYEAAIEAalGGRLQAVVVENLNAAKKAIAFLK---QNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  547 LQLQGKRAEEGDHEVLdQKEMKQMEGEGIAPIKMEVFLEDTGQNFplmpneESSLPAVEKEQASTEHQNRTSEEISLNDA 626
Cdd:TIGR02168  578 LDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  627 GVELKS-----TKQDCDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNA 701
Cdd:TIGR02168  651 DGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  702 DNNSSAFTALSEERDQLLAQVKELSvvtelrAQVRQLEMNLAEAERQRrfdyesqtahhNLLTEQIHSLSIEAKSKDVKI 781
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  782 EVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETL 861
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  862 QQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspa 938
Cdd:TIGR02168  865 EELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--- 941

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622909132  939 glisKEELQHEFDLLKKENEQRKRKLQAALinrKELLQRVSRLEEELANL 988
Cdd:TIGR02168  942 ----QERLSEEYSLTLEEAEALENKIEDDE---EEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 727-1062 1.04e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 1.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  727 VVTELRAQVRQLEmnlAEAERQRRFdyesqtahhNLLTEQIHSLSIEAKSKdvKIEVLQNELDDVQLQFSEQSTLIRSLQ 806
Cdd:COG1196    194 ILGELERQLEPLE---RQAEKAERY---------RELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  807 SQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQL 886
Cdd:COG1196    260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  887 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDemspagliskEELQHEFDLLKKENEQRKRkLQA 966
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE----------ELAEELLEALRAAAELAAQ-LEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  967 ALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSekcvtskcQEIEISLKQTISEKEVELEHIR 1046
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL--------EEEEEALLELLAELLEEAALLE 476

                          330
                   ....*....|....*.
gi 1622909132 1047 KDLEEKMAAEEQLQAL 1062
Cdd:COG1196    477 AALAELLEELAEAAAR 492
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2414-3157 1.54e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.39  E-value: 1.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2414 LNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSV---ILEKDQLIQEAAAENNKLKEEIRGLRSHMDD 2490
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELeeeIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2491 LNSENAKLDAELIQYREDLNQVISIKDSQQKQL------LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQE 2564
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2565 EKRDLSKEIESLKVSVSQLTRQVTALQEE-----------------GTLGIYHAQLKVKEEELQRLSALLSSSQKRITEL 2627
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2628 EEELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMV 2691
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2692 TKENKDLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSM 2762
Cdd:TIGR02168  554 NLNAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2763 DLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpats 2842
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEEL----------------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2843 LAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQL 2922
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2923 RMEKSSWEIHERRMKEQYLMAisDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRN 3002
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 3003 QLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNI 3082
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRR 915

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132 3083 DvapgapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSLAEEQIRRLE 3157
Cdd:TIGR02168  916 E-------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1464-2057 2.10e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.01  E-value: 2.10e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1464 ALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMD---RSLLENQSLSGSCES 1540
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1541 LKLALEGLTEDKEKL---VKEIESLKSSKIAESSEWQEKHKELQ------KEYEIL---LQSYENVSNEAERIQHVVEAV 1608
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLsefYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1609 RQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskqQKILELEEENDRLRAEVhpaGGTAKECMETLLS 1688
Cdd:PRK03918   323 INGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY-----EEAKAKKEELERLKKRL---TGLTPEKLEKELE 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1689 SNASMKEEVERvkmEYETLSKKFQSLMSEKDSLSEEVQDLKHQleSNVSKQANLEATEKHdnQMNVTEEATQSIPGETED 1768
Cdd:PRK03918   395 ELEKAKEEIEE---EISKITARIGELKKEIKELKKAIEELKKA--KGKCPVCGRELTEEH--RKELLEEYTAELKRIEKE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1769 QDSLSMSTRPACSESVPSENSANPavSEDVSSHDEInnyLQQIDQLKERIAG--LEEEKQKNKEFSQTLEnernallsQI 1846
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKK--ESELIKLKEL---AEQLKELEEKLKKynLEELEKKAEEYEKLKE--------KL 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1847 STKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLESE 1926
Cdd:PRK03918   535 IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYNE 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1927 MKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKIS 2005
Cdd:PRK03918   604 YLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSRELA 676

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622909132 2006 ALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2057
Cdd:PRK03918   677 GLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 654-1100 7.83e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.14  E-value: 7.83e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  654 ELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKElsvvtelra 733
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHK--------- 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  734 qvRQLEMNLAEAERQRRFDYESQTAhhnllteqihslsieakskdVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKE 813
Cdd:pfam15921  389 --REKELSLEKEQNKRLWDRDTGNS--------------------ITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  814 SEVL-------EGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQL 886
Cdd:pfam15921  447 ERQMaaiqgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSR 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  887 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMS--------PAGLISKEELQ----------- 947
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTqlvgqhgrTAGAMQVEKAQlekeindrrle 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  948 -HEFDLLKKENEQRKRKLQAALINRK-ELLQRVSRLEEELANLKDQSKKEIPL---SESERGEVEEDKENKEYSEKCVTS 1022
Cdd:pfam15921  606 lQEFKILKDKKDAKIRELEARVSDLElEKVKLVNAGSERLRAVKDIKQERDQLlneVKTSRNELNSLSEDYEVLKRNFRN 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1023 KCQEIEIS---LKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEIsenQVIIQKLTTSNT 1099
Cdd:pfam15921  686 KSEEMETTtnkLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI---QFLEEAMTNANK 762


                   .
gi 1622909132 1100 D 1100
Cdd:pfam15921  763 E 763
PTZ00121 PTZ00121
MAEBL; Provisional
 1872-2497 2.39e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.62  E-value: 2.39e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1872 EELSRVTKLKETAEEEKDDLEER---LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE--EEKQQLVK 1946
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERnneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKkaEEKKKADE 1306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1947 EKTKVESEIRKEYLEKiqgaqKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLE 2026
Cdd:PTZ00121  1307 AKKKAEEAKKADEAKK-----KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD 1381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2027 ITK---ENLAQAVEHRKKAQAELASFKVLlddTQSEAARVLADNLKLKKELQSNKESVK--SQMKQKDEDLERRLEQAEE 2101
Cdd:PTZ00121  1382 AAKkkaEEKKKADEAKKKAEEDKKKADEL---KKAAAAKKKADEAKKKAEEKKKADEAKkkAEEAKKADEAKKKAEEAKK 1458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2102 -KHLKEKKNMQEKLDALRR---EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQD-DRDRVIDE 2176
Cdd:PTZ00121  1459 aEEAKKKAEEAKKADEAKKkaeEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaEEAKKADE 1538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2177 AKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENK 2256
Cdd:PTZ00121  1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2257 ----ELLSQLEETRHLYHNSQN----------ELAKLESELNILKDQLTdlsnslEKCKEQKENLEGIiRQQEADIQNSK 2322
Cdd:PTZ00121  1619 kikaEELKKAEEEKKKVEQLKKkeaeekkkaeELKKAEEENKIKAAEEA------KKAEEDKKKAEEA-KKAEEDEKKAA 1691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2323 FSYEQLETDLQASRELTSRLHEEINMKEQkmislLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKK 2402
Cdd:PTZ00121  1692 EALKKEAEEAKKAEELKKKEAEEKKKAEE-----LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2403 AVDKTNQLMETLNAIK----KENIQQKAQLDSFVKSMSSL-------QNDRDRIVGDYQQLEerhlsvilekDQLIQEAA 2471
Cdd:PTZ00121  1767 EKKAEEIRKEKEAVIEeeldEEDEKRRMEVDKKIKDIFDNfaniiegGKEGNLVINDSKEME----------DSAIKEVA 1836

                          650       660
                   ....*....|....*....|....*.
gi 1622909132 2472 AENNKLKEEIRGLRSHMDDLNSENAK 2497
Cdd:PTZ00121  1837 DSKNMQLEEADAFEKHKFNKNNENGE 1862
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 24-578 5.67e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 5.67e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132   24 ELKDIIRQKDVQLQ-QKDEALQEEKKAADNKIKKLKLHAKakltSLNKHIEEMKAQGGTVLLTEPQSEEQLSKHDKSSTE 102
Cdd:COG1196    217 ELKEELKELEAELLlLKLRELEAELEELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  103 EEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEmkefvmmKQQLQEKEELISTLQAQLSQTQAEQAAQLS 182
Cdd:COG1196    293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL-------EEELEELEEELEEAEEELEEAEAELAEAEE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  183 SMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESlvgRAQVVDLLQQELTAAEQRNQILS 262
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL---EEELEELEEALAELEEEEEEEEE 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  263 QQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLsfhNLQEEMRHLLEQLEQAGQAQAELESRySALEQKHKAE 342
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL---LEELAEAAARLLLLLEAEADYEGFLE-GVKAALLLAG 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  343 MEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAqtIEQLEDQ---------LQQKSKEISQFLNRLPLQ 413
Cdd:COG1196    519 LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA--IEYLKAAkagratflpLDKIRARAALAAALARGA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  414 QHETASQTCFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRIGEADREV 493
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  494 SEISIVDDANKRSSSTEESGQDVLENtfSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEGDHEVLDQKEMKQMEGE 573
Cdd:COG1196    677 AEAELEELAERLAEEELELEEALLAE--EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754


                   ....*
gi 1622909132  574 GIAPI 578
Cdd:COG1196    755 ELPEP 759
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 881-1732 1.07e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.53  E-value: 1.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  881 EKMVQLNEEKFSLGVEIKTLKEQ-LNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagLISKEELQHEFDLLKKENEQ 959
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQeLKLKEQAKKALEYYQLKEKLELEEEYLLYLDY----LKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  960 RKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKE 1039
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1040 VELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPP 1119
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1120 G-TDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1198
Cdd:pfam02463  412 ElARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLS 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1199 GDQLRQLQIQVRESIDG--KLPSPDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDA-----SALQGGT 1271
Cdd:pfam02463  492 RQKLEERSQKESKARSGlkVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEveerqKLVRALT 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1272 SVAQIKAQLKEIETEKEKLELKISSTTSELT--------KKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKL 1343
Cdd:pfam02463  572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPIlnlaqldkATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1344 ESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERI 1423
Cdd:pfam02463  652 VSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQ 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1424 KQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEK 1503
Cdd:pfam02463  732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1504 DRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKE 1583
Cdd:pfam02463  812 EEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESK 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1584 YEillqsyenvsneaeriqhvvEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEE 1663
Cdd:pfam02463  892 EE--------------------KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKE 951

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909132 1664 ENDRLRAEVHPAGGTAKEcmETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQL 1732
Cdd:pfam02463  952 ENNKEEEEERNKRLLLAK--EELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1916-2729 2.21e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.90  E-value: 2.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1916 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 1995
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1996 DCIRYQEKISALERTVKalefvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2075
Cdd:pfam02463  259 EIEKEEEKLAQVLKENK-------EEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2076 SNKESVKSQMKQKDEDLERRL------EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2149
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREaeeeeeEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2150 dstvaQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHD 2229
Cdd:pfam02463  412 -----ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2230 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILK--DQLTDLSNSLEKCKEQKENL 2307
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAisTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2308 EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS 2387
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2388 QEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLI 2467
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2468 QEAAAENNKLKEEIR----------GLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNK 2537
Cdd:pfam02463  727 VQEAQDKINEELKLLkqkideeeeeEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2538 YAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALL 2617
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2618 SSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKD 2697
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1622909132 2698 LTAQIQSFGRSMSSLQNSRDHANEELDELKRK 2729
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
PTZ00121 PTZ00121
MAEBL; Provisional
 671-1198 8.88e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.15  E-value: 8.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  671 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQ 748
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  749 RRFDYESQTAHHNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 821
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  822 RVRHISSKVEELSQA--LSQKELEIAKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 897
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  898 KTLKEqlnlLSRAEEAKKEQVEEDNEVvsglKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 977
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  978 VSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEE 1057
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1058 QLQAlvKEMNQTLQDKTNQIDLLQAEISENQviiqklttsntdasdgdsvalvketvvisppgtdsgehwKPELEEKILA 1137
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909132 1138 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1198
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 313-1093 6.16e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.43  E-value: 6.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  313 HLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQL 392
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  393 -------EDQLQQKSKEISQFlnRLPLQQHETASQ---TCFPDVYNEGTQAVTEENIAS----------LQKRVVELENE 452
Cdd:pfam15921  155 eaakclkEDMLEDSNTQIEQL--RKMMLSHEGVLQeirSILVDFEEASGKKIYEHDSMStmhfrslgsaISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  453 ----KGALLLSSIELEELKAENEKlSSQITLLEAQNRIGEADREvSEISIVDDANKRSS--STEESGQDVLENTFSQKHK 526
Cdd:pfam15921  233 isylKGRIFPVEDQLEALKSESQN-KIELLLQQHQDRIEQLISE-HEVEITGLTEKASSarSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  527 ELSVLLLEMKEAQEEIAFLKLQL-QGKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDTGQNFPLMPNEESSLPAVE 605
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRSELrEAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKRE 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  606 KEQASTEHQNR------TSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQIlelelnfhkaqeiyeKN 679
Cdd:pfam15921  391 KELSLEKEQNKrlwdrdTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI---------------QG 455

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  680 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSvvTELRAQVRQLEMNLAEAERQR-RFDYESQTA 758
Cdd:pfam15921  456 KNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLT--ASLQEKERAIEATNAEITKLRsRVDLKLQEL 533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  759 HHnLLTEQIHslsieakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS 838
Cdd:pfam15921  534 QH-LKNEGDH------------LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIN 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  839 QKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKM---VQLNEEKFSLGVEIKTLKEQLNLLSraeeakk 915
Cdd:pfam15921  601 DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLS------- 673

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  916 eqveEDNEVvsgLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELAnlkdqskke 995
Cdd:pfam15921  674 ----EDYEV---LKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQIT--------- 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  996 iplseSERGEVEEDKENKEYSEKCVTSKCQEIEIsLKQTISEKEVELEHIRKDlEEKMAAE-EQLQALVKEMNQTLQDKT 1074
Cdd:pfam15921  738 -----AKRGQIDALQSKIQFLEEAMTNANKEKHF-LKEEKNKLSQELSTVATE-KNKMAGElEVLRSQERRLKEKVANME 810

                          810
                   ....*....|....*....
gi 1622909132 1075 NQIDLLQAEISENQVIIQK 1093
Cdd:pfam15921  811 VALDKASLQFAECQDIIQR 829
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 8-258 2.02e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 2.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132    8 QEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEEKKAADNKIKKLKLHAKakltSLNKHIEEMKAQGGTVLLTEP 87
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA----RLEERRRELEERLEELEEELA 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132   88 QSEEQLSKHDKSSTEEEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMKQQLQEKEELISTLQ 167
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  168 AQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEEslvGRAQVVDLL 247
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL---LEAALAELL 483

                          250
                   ....*....|.
gi 1622909132  248 QQELTAAEQRN 258
Cdd:COG1196    484 EELAEAAARLL 494
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2647-2873 1.14e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2647 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDEL 2726
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2727 KRKYDASLKELAQLKEQQGLLnrerhALLSETTFsmdLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSK 2806
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLA-----LLLSPEDF---LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 2807 AMASLQNERDHLWNELEKFRKSEEGKQRSAAQpatslaEVQSLKKAMSSLQNDRDRLLKELKNLQQQ 2873
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIARLEAE 235
mukB PRK04863
chromosome partition protein MukB;
2664-2987 2.23e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 2.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2664 RNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDH------------------------- 2718
Cdd:PRK04863   292 RRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQqekieryqadleeleerleeqnevv 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2719 --ANEELDELKRKYDASLKELAQLKEQ-----QGLLNRERHAL-----------LSETTFSMDLPEENSLSYLEKLNQQL 2780
Cdd:PRK04863   372 eeADEQQEENEARAEAAEEEVDELKSQladyqQALDVQQTRAIqyqqavqalerAKQLCGLPDLTADNAEDWLEEFQAKE 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2781 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQN-----ERDHLWNE-LEKFRKSEEgkQRSAAQPATSL-AEVQSLKKAM 2853
Cdd:PRK04863   452 QEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKiagevSRSEAWDVaRELLRRLRE--QRHLAEQLQQLrMRLSELEQRL 529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2854 sSLQNDRDRLLKELKNLQQQYLQINQEITELR-PLKAQLQEYQDKTKTFQIMQEELRQENLSWQHELHQLRMEKSSW-EI 2931
Cdd:PRK04863   530 -RQQQRAERLLAEFCKRLGKNLDDEDELEQLQeELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWlAA 608

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909132 2932 HER--RMKEQYLMAISDKDQQVSHLQNLIRELRS-------SSSQAQPLKVQYQRQASPETSASP 2987
Cdd:PRK04863   609 QDAlaRLREQSGEEFEDSQDVTEYMQQLLEREREltverdeLAARKQALDEEIERLSQPGGSEDP 673
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2529-3050 2.01e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.95  E-value: 2.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2529 QQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLS-------KEIESLKVSVSQLTRQVTALQEEGTLGIYHA 2601
Cdd:pfam15921  138 QSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMlshegvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRS 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2602 QLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLhhdagIMRNETE-TAEERVAELARD 2680
Cdd:pfam15921  218 LGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQL-----ISEHEVEiTGLTEKASSARS 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2681 LVEMEQKLLMVTKENKdlTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELA------------------QLKE 2742
Cdd:pfam15921  293 QANSIQSQLEIIQEQA--RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlanseltearterdQFSQ 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2743 QQGLLNRERHALLSETTfsmdlPEENSLSYLEKLNQQLLSKDE----QLLHLSSQLEDSYNQVQ---------------S 2803
Cdd:pfam15921  371 ESGNLDDQLQKLLADLH-----KREKELSLEKEQNKRLWDRDTgnsiTIDHLRRELDDRNMEVQrleallkamksecqgQ 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2804 FSKAMASLQNERDHLWN--------------------ELEKFRKSEEGKQRSAAQPATSLAE----VQSLKKAMSSLQND 2859
Cdd:pfam15921  446 MERQMAAIQGKNESLEKvssltaqlestkemlrkvveELTAKKMTLESSERTVSDLTASLQEkeraIEATNAEITKLRSR 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2860 RDRLLKELKNLQQQYLQINQEITELRPLKAQLQEyqdKTKTFQIMQEELRQ-ENLSWQH-------ELHQLRMEKsswEI 2931
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAE---KDKVIEILRQQIENmTQLVGQHgrtagamQVEKAQLEK---EI 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2932 HERRMKEQYLMAISDKDQQVshlqnlIRELRSSSSQAQPLKVQYQRQASPETSASPDGSQ---NLIYETELLRNQLNdSL 3008
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAK------IRELEARVSDLELEKVKLVNAGSERLRAVKDIKQerdQLLNEVKTSRNELN-SL 672

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1622909132 3009 KEihQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQ 3050
Cdd:pfam15921  673 SE--DYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2006-2175 3.80e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 42.29  E-value: 3.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2006 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2081
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2082 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2138
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1622909132 2139 DKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2175
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
463-990 9.96e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.56  E-value: 9.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  463 LEELKAENEKLSSQiTLLEAQNRIGEADREV-SEISIVDDANKRSSSTEESGQDVLEnTFSQKHKELSVLLLEMKEAQEE 541
Cdd:PRK02224   189 LDQLKAQIEEKEEK-DLHERLNGLESELAELdEEIERYEEQREQARETRDEADEVLE-EHEERREELETLEAEIEDLRET 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  542 IAFLKlqlqgKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDtgqnfplmpneeSSLPAVEKEQASTEHQNRTSEEi 621
Cdd:PRK02224   267 IAETE-----REREELAEEVRDLRERLEELEEERDDLLAEAGLDD------------ADAEAVEARREELEDRDEELRD- 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  622 SLNDAGVELKSTKQDCDKSLSAVPDigqcHQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNA 701
Cdd:PRK02224   329 RLEECRVAAQAHNEEAESLREDADD----LEERAEELREEAAELESELEEARE----AVEDRREEIEELEEEIEELRERF 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  702 DNNSSAFTALSEERDQLLAQVKEL-SVVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHnlLTEQIHSLSIEakSKDVK 780
Cdd:PRK02224   401 GDAPVDLGNAEDFLEELREERDELrEREAELEATLRTARERVEEAEALLEAGKCPECGQP--VEGSPHVETIE--EDRER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  781 IEVLQNELDDVQLQFS------EQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEK 854
Cdd:PRK02224   477 VEELEAELEDLEEEVEeveerlERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  855 KRDVETLQQTIEEKDQQVTEISFSMTE---------KMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVV 925
Cdd:PRK02224   557 REAAAEAEEEAEEAREEVAELNSKLAElkeriesleRIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERK 636

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909132  926 SGLKQNYDEMspagliSKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKD 990
Cdd:PRK02224   637 RELEAEFDEA------RIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEE 695
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1870-2742 2.79e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.28  E-value: 2.79e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1870 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1939
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1940 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2012
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2013 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD---------DTQSEAARVLADNLK------------LK 2071
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEeleaeleelESRLEELEEQLETLRskvaqlelqiasLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2072 KELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2151
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2152 TVAQLAAFTKSMSSLQDDRDRV------IDEAKKWERKFSDAIQTKEEEIRLKE--ENCSVLKDQLRQMSIHMEELKINI 2223
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLegfsegVKALLKNQSGLSGILGVLSELISVDEgyEAAIEAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2224 SRLEHDKQIWESKAqTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQL---TDLSNSLEKC 2300
Cdd:TIGR02168  560 KAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2301 KeqKENLEGIIRQQEADIQNSKFSYEQletdlQASRELTSRLHEEINMKEqkmislLSGKEEAIQVAIAELRQQHDKEIK 2380
Cdd:TIGR02168  639 K--KLRPGYRIVTLDGDLVRPGGVITG-----GSAKTNSSILERRREIEE------LEEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2381 ELENLLSQEEeenivleeenkkavdktnqlmetlnaikkeniQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsvI 2460
Cdd:TIGR02168  706 ELEELEEELE--------------------------------QLRKELEELSRQISALRKDLARLEAEVEQLEER----I 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2461 LEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleaqlqqnKELKNKYAK 2540
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAAN 821

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2541 LEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyhaqLKVKEEELQRLSALLSSS 2620
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALL 892

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2621 QKRITELEEELvcvqKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENK 2696
Cdd:TIGR02168  893 RSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEE 968

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*.
gi 1622909132 2697 DLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2742
Cdd:TIGR02168  969 EARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1271-2056 6.61e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.13  E-value: 6.61e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1271 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGL-EIESLKTASHEAEVRAESLQQKLESSQLQ 1349
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1350 iaglehLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1426
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1427 QVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARDTIEHLTKSLADVESH 1495
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1496 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEG-------LTEDKEKLVKEIESLKSSKIA 1568
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqLGSVGERYATAIEVAAGNRLN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1569 ----ESSEWQEKHKELQKEYEILLQSYENVsNEAERIQHVVEAVRQEKQELYGklrsteANKKETEKQLQEAEKEMEEMK 1644
Cdd:TIGR02169  551 nvvvEDDAVAKEAIELLKRRKAGRATFLPL-NKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1645 EKMRKFAKSKQQ--KILELEEENDRLRAEVHPAGGTAKECMETLLSsnASMKEEVERVKMEYETLSKKFQSLMSEKDSLS 1722
Cdd:TIGR02169  624 LVVEDIEAARRLmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFS--RSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1723 EEVQDLKHQLESnvsKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSlsmstrpacsesvpsensanpavsedvSSHD 1802
Cdd:TIGR02169  702 NRLDELSQELSD---ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS---------------------------SLEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1803 EINNYLQQIDQLKERIAGLEEEKQKNKEfsQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE 1882
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEE--ALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1883 TAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1962
Cdd:TIGR02169  830 YLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1963 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR-------------YQEKISALERTVKALEFVQTESQKDLEITK 2029
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelsledVQAELQRVEEEIRALEPVNMLAIQEYEEVL 985

                          810       820
                   ....*....|....*....|....*..
gi 1622909132 2030 ENLAQAVEHRKKAQAELASFKVLLDDT 2056
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1287-2149 1.41e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.97  E-value: 1.41e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1287 KEKLELKISSTTSELTkkseevfQLQDQINKQGLEIESLKTASHEAEvRAESLQQKLESSQLQIAGLEhLRELQPELDEL 1366
Cdd:TIGR02168  174 RKETERKLERTRENLD-------RLEDILNELERQLKSLERQAEKAE-RYKELKAELRELELALLVLR-LEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1367 QKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIEEE 1443
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1444 SRAKQQIQRKLQAALISRKEALKEnksLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERdklite 1523
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEE---LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI------ 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1524 mdrsllenQSLSGSCESLKLALEGLTEDKEKLVKEIESL-KSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQ 1602
Cdd:TIGR02168  396 --------ASLNNEIERLEARLERLEDRRERLQQEIEELlKKLEEAELKELQAELEELEEELEELQEELERLEEALEELR 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1603 HVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaekemeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGgtakec 1682
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQARLDSLERLQEN---------------LEGFSEGVKALLKNQSGLSGILGVLS------ 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1683 meTLLSSNASMKEEVERVkmeyetLSKKFQSLMSEkdSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTE-EATQS 1761
Cdd:TIGR02168  527 --ELISVDEGYEAAIEAA------LGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDrEILKN 596

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1762 IPGetedqdslsmsTRPACSESVPSENSANPAVS---EDVSSHDEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLE 1836
Cdd:TIGR02168  597 IEG-----------FLGVAKDLVKFDPKLRKALSyllGGVLVVDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGG 664

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1837 NERNAllSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDA 1916
Cdd:TIGR02168  665 SAKTN--SSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARL 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1917 QIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQK 1995
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNE 817

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1996 DCIRYQEKISALERTVKALEfvqtesqKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQ 2075
Cdd:TIGR02168  818 EAANLRERLESLERRIAATE-------RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLE 886

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622909132 2076 SNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2149
Cdd:TIGR02168  887 EALALLRSELEELSEEL---------------RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 727-1615 3.51e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 3.51e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  727 VVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLsieakskdvkievlQNELDDVQLQFSEQSTLIRSLQ 806
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL--------------REELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  807 SQLQNKESEvlegaervrhisskveelsqaLSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQL 886
Cdd:TIGR02168  260 AELQELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  887 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAglisKEELQHEFDLLKKENEQRKRKLQA 966
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  967 ALINRKELLQRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIR 1046
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1047 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASdgdsvALVKETVVISPPGTDSGEH 1126
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK-----ALLKNQSGLSGILGVLSEL 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1127 WKPElEEKILALEKEkeqLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIG 1199
Cdd:TIGR02168  529 ISVD-EGYEAAIEAA---LGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1200 DQLRQLQIQVRESIDGKLPSpdqqewCSPTPGLEEplfkATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQ 1275
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLGG------VLVVDDLDN----ALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILE 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1276 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEH 1355
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1356 lrelqpELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHderiKQLQVELCEMKQ 1435
Cdd:TIGR02168  755 ------ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL----TLLNEEAANLRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1436 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEhltkslADVESHVsaqnKEKDRVLGRLALLQE 1515
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE------SELEALL----NERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1516 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEssewqekhkELQKEYEILLQSYENVS 1595
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIE 964

                          890       900
                   ....*....|....*....|
gi 1622909132 1596 NEAERIQHVVEAVRQEKQEL 1615
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 652-1502 4.52e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 4.52e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  652 QDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV-VTE 730
Cdd:TIGR02168  192 EDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEkLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  731 LRAQVRQLEMNLAEAerQRRFdyesqtahhnllteqiHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQ 810
Cdd:TIGR02168  272 LRLEVSELEEEIEEL--QKEL----------------YALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  811 NKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEK 890
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL----NNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  891 FSLGVEIKTLKEQLN-LLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALI 969
Cdd:TIGR02168  410 ERLEDRRERLQQEIEeLLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  970 NRKELLQRVSRLEEELANLKDQSKKEIPLSE-----SERGEVEEDKEN------KEYSEKCVTSKCQEIEI---SLKQTI 1035
Cdd:TIGR02168  490 RLDSLERLQENLEGFSEGVKALLKNQSGLSGilgvlSELISVDEGYEAaieaalGGRLQAVVVENLNAAKKaiaFLKQNE 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1036 SEKEVELE-------HIRKDLEEKMAAEEQLQALVKEmnqtLQDKTNQIDLLQAEISENQVIIQKLTTSNTDAS--DGDS 1106
Cdd:TIGR02168  570 LGRVTFLPldsikgtEIQGNDREILKNIEGFLGVAKD----LVKFDPKLRKALSYLLGGVLVVDDLDNALELAKklRPGY 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1107 VALVKETVVISPPGTDSGEHWKPELeeKILALEKEKEQLQKKLqEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQE 1186
Cdd:TIGR02168  646 RIVTLDGDLVRPGGVITGGSAKTNS--SILERRREIEELEEKI-EELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1187 QFDEQSKENENIGDQLRQLQIQVRESIDgkLPSPDQQEWCSPTPGLEEPLFKATEQhhtqpvlesnlcpdwpshsedasa 1266
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIA--QLSKELTELEAEIEELEERLEEAEEE------------------------ 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1267 lqggtsVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESS 1346
Cdd:TIGR02168  777 ------LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1347 QLQIAGLEH--------LRELQPELDELQKLISEKEEDVSY-------LSGQLREKEAALTKIQTEIIEQEDLIKALHTQ 1411
Cdd:TIGR02168  851 SEDIESLAAeieeleelIEELESELEALLNERASLEEALALlrseleeLSEELRELESKRSELRRELEELREKLAQLELR 930

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1412 L---EMQAKEHDERI-KQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARDTIE 1483
Cdd:TIGR02168  931 LeglEVRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKE 1010

                          890
                   ....*....|....*....
gi 1622909132 1484 HLTKSLADVESHVSAQNKE 1502
Cdd:TIGR02168 1011 DLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1275-2049 5.35e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 5.35e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1275 QIKAQLKEIE-----TEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQ 1349
Cdd:TIGR02168  217 ELKAELRELElallvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1350 IAGLEH-LRELQPELDELQKLISEKEEdvsylsgQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQv 1428
Cdd:TIGR02168  297 ISRLEQqKQILRERLANLERQLEELEA-------QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE- 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1429 elcEMKQKPEEIEEESRAKQQiqrklqaaliSRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNK-----EK 1503
Cdd:TIGR02168  369 ---ELESRLEELEEQLETLRS----------KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKkleeaEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1504 DRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKS-----SKIAESSEWQEKHK 1578
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqenlEGFSEGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1579 ELQKEYEILLQSYENVSNE---------AERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRK 1649
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILK 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1650 FAKSKQQKILELEEENDRLRAEVHPAGGTAKeCMETLLSSNA---SMKEEVERVKMEYETLSKKF----------QSLMS 1716
Cdd:TIGR02168  596 NIEGFLGVAKDLVKFDPKLRKALSYLLGGVL-VVDDLDNALElakKLRPGYRIVTLDGDLVRPGGvitggsaktnSSILE 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1717 EKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQM-NVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVS 1795
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELeEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1796 EDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELS 1875
Cdd:TIGR02168  755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1876 RVTKLKETAEEEKDDLEErlmnQLAELNGSIgnycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEI 1955
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSE----DIESLAAEI-------EELEELIEELESELEALLNERASLEEALALLRSELEELSEEL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1956 RKEylekiqgaqkepgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2035
Cdd:TIGR02168  904 REL--------------ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969

                          810
                   ....*....|....*
gi 1622909132 2036 VEHR-KKAQAELASF 2049
Cdd:TIGR02168  970 ARRRlKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1976-2893 7.14e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 7.14e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1976 AKELQELLKEKQQEVKQLQKdCIRYQEKISALERTVKALEFVQTESQkdLEITKENLAQAVEHRKKAQAELASFKVLLDD 2055
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAER-YKELKAELRELELALLVLRLEELREE--LEELQEELKEAEEELEELTAELQELEEKLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2056 TQSEAARVLADNLKLKKELQSnkesvksqMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRREKVHLEETIGEIQVTL 2135
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYA--------LANEISRLEQQKQILRER----LANLERQLEELEAQLEELESKLDELAEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2136 NKKDKEIQQVQENLDSTVAQLAAFTKSmssLQDDRDRVIDEAKKWERKFSDAIQTKEEEirlkeencSVLKDQLRQMSIH 2215
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELEELEAE---LEELESRLEELEEQLETLRSKVAQLELQI--------ASLNNEIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2216 MEELKINISRLEHDKQIWESKAQ-TEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLS 2294
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2295 NSLEKCKEQKENLEGIIRQQEADIQNSkfsyEQLETDLQASRELtsrlheeinmkeqkmISLLSGKEEAIQVAIAELRQQ 2374
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKNQ----SGLSGILGVLSEL---------------ISVDEGYEAAIEAALGGRLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2375 ----HDKEIKELENLLSQeeeenivleeenkKAVDKTNQLMETL---NAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVG 2447
Cdd:TIGR02168  550 vvveNLNAAKKAIAFLKQ-------------NELGRVTFLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRK 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2448 DYQQLeerhLSVILEKDQLiQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKqlLEAQ 2527
Cdd:TIGR02168  617 ALSYL----LGGVLVVDDL-DNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEK--IEEL 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2528 LQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKE 2607
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE--LTELEAEIEELE 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2608 EELQRLSALLSSSQKRITELEEElVCVQKEAAKKVGEIEDKLKKELKHLHHDAGimrneteTAEERVAELARDLVEMEQK 2687
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAA-------NLRERLESLERRIAATERR 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2688 LLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRErhallsettfsmdlpee 2767
Cdd:TIGR02168  840 LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE----------------- 902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2768 nslsyLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSfskamasLQNERDHLWNEL-EKFRKSEEGkqrSAAQPATSLAEV 2846
Cdd:TIGR02168  903 -----LRELESKRSELRRELEELREKLAQLELRLEG-------LEVRIDNLQERLsEEYSLTLEE---AEALENKIEDDE 967

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622909132 2847 QSLKKAMSSLQNDRDRL-------LKELKNLQQQYLQINQEITELRPLKAQLQE 2893
Cdd:TIGR02168  968 EEARRRLKRLENKIKELgpvnlaaIEEYEELKERYDFLTAQKEDLTEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1801-2498 4.61e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 4.61e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1801 HDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKL 1880
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1881 KETAEEEKDDLEERLMNQLAELNGS---IGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1957
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELeekLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1958 EYLE-KIQGAQKEPGNKSHAKELQELLK-EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTEsqkdLEITKENLAQA 2035
Cdd:TIGR02168  398 LNNEiERLEARLERLEDRRERLQQEIEElLKKLEEAELKELQAELEELEEELEELQEELERLEEA----LEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2036 VEHRKKAQAELASFKVLLDDTQSEAARVL-----ADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK----E 2106
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEgfsegVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavvvE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2107 KKNMQEK-LDALRREKVH----LEETI---GEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSL------QDDRDR 2172
Cdd:TIGR02168  554 NLNAAKKaIAFLKQNELGrvtfLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2173 VIDEAKKW-----------------------ERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLE-- 2227
Cdd:TIGR02168  634 ALELAKKLrpgyrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEee 713

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2228 ---------------HDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTD 2292
Cdd:TIGR02168  714 leqlrkeleelsrqiSALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2293 LSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLlsgkeeaiQVAIAELR 2372
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL--------AAEIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2373 QQHDKEIKELENLLSQEEEENIVLEEENKKAvdktNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2452
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSEL----EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909132 2453 EERhlsvILEKDQLIQEAAAEN-NKLKEEIRGLRSHMDDLNSENAKL 2498
Cdd:TIGR02168  942 QER----LSEEYSLTLEEAEALeNKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2178-2911 4.69e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 4.69e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2178 KKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDkqiwESKAQTEVQLQQKVCDTLQGENKE 2257
Cdd:TIGR02168  203 KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEE----LEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2258 LLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRE 2337
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2338 LtsrlHEEINMKEQKMISLLSGKEEAIQV---AIAELRQQ---HDKEIKELENLLSQEEEENIVLEEENKKAVDKT---- 2407
Cdd:TIGR02168  359 E----LEELEAELEELESRLEELEEQLETlrsKVAQLELQiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLeeae 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2408 -NQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERH---------LSVILEKDQLIQEAAAENNKL 2477
Cdd:TIGR02168  435 lKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlqarldsLERLQENLEGFSEGVKALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2478 KEEIRGLRSHMDDLNSENAKLDAEL-IQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQ 2556
Cdd:TIGR02168  515 QSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2557 RSSNALQEEKRDLSKEIESLKVSVS--------------------QLTRQVTALQEEGTLgIYHAQLKVKEEELQRLSAL 2616
Cdd:TIGR02168  595 KNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldnalelakKLRPGYRIVTLDGDL-VRPGGVITGGSAKTNSSIL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2617 lsSSQKRITELEEELvcvqkeaaKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENK 2696
Cdd:TIGR02168  674 --ERRREIEELEEKI--------EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2697 DLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSEttfsmdlpeenslsyLEKL 2776
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA---------------LDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2777 NQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQrsaAQPATSLAEVQSLKKAMSSL 2856
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE---ELIEELESELEALLNERASL 885

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909132 2857 QNDRDRLLKELKNLQQQYLQINQEITELRplkAQLQEYQDKTKTFQIMQEELRQE 2911
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELR---RELEELREKLAQLELRLEGLEVR 937
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1275-1822 4.85e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 4.85e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1275 QIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE 1354
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1355 H-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1433
Cdd:COG1196    316 ErLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1434 KQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALL 1513
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1514 QEERDKLitemDRSLLENQSLSGSCESLKLALEGLTED-KEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYE 1592
Cdd:COG1196    476 EAALAEL----LEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1593 NVSNEAERIqhvvEAVRQEKQELYGK-----LRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDR 1667
Cdd:COG1196    552 VVEDDEVAA----AAIEYLKAAKAGRatflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1668 LRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEK 1747
Cdd:COG1196    628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909132 1748 HDNQMNVTEEATQSIpgETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLE 1822
Cdd:COG1196    708 ELAEAEEERLEEELE--EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 888-1728 8.05e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 8.05e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  888 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLkQNYDEmspagliSKEELQHEFDLLKKENEQRKRKLQAA 967
Cdd:TIGR02168  222 LRELELALLVLRLEELREELEELQEELKEAEEELEELTAEL-QELEE-------KLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  968 LINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEiSLKQTISEKEVELEHIRK 1047
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE-SLEAELEELEAELEELES 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1048 DLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvisppGTDSGEHw 1127
Cdd:TIGR02168  373 RLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL------QAELEEL- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1128 KPELEEKILALEKEKEQLqKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLqEQFDEQSKENENIGDQLRQLQI 1207
Cdd:TIGR02168  446 EEELEELQEELERLEEAL-EELREELEEAEQALDAAERELAQLQARLDSLERLQENL-EGFSEGVKALLKNQSGLSGILG 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1208 QVRESIdgklpspdqqewcSPTPGLEEPLFKATEQHhTQPVLESNLCPDWPSHSEDASALQGGTSVAQIK----AQLKEI 1283
Cdd:TIGR02168  524 VLSELI-------------SVDEGYEAAIEAALGGR-LQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDsikgTEIQGN 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1284 ETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASH-----EAEVRAESLQQKLESSQLQIAGLEHLRE 1358
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALElakklRPGYRIVTLDGDLVRPGGVITGGSAKTN 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1359 LQP-----ELDELQKLISEKEEdvsylsgQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELcem 1433
Cdd:TIGR02168  670 SSIlerrrEIEELEEKIEELEE-------KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE--- 739

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1434 kqkpEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALL 1513
Cdd:TIGR02168  740 ----AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1514 QEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLksskiaessewQEKHKELQKEYEILLqsyen 1593
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL-----------EELIEELESELEALL----- 879

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1594 vsNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskQQKILELEEendRLRAEVH 1673
Cdd:TIGR02168  880 --NERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL----EVRIDNLQE---RLSEEYS 950

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909132 1674 PAGGTAKECMETLLSSNASMKEEVERVKM--------------EYETLSKKFQSLMSEKDSLSEEVQDL 1728
Cdd:TIGR02168  951 LTLEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaaieEYEELKERYDFLTAQKEDLTEAKETL 1019
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1311-1895 2.08e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 2.08e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1311 LQDQINKQgleIESLKTashEAEV--RAESLQQKLESSQLQIAGLeHLRELQPELDELQKLISEKEEDVSYLSGQLREKE 1388
Cdd:COG1196    194 ILGELERQ---LEPLER---QAEKaeRYRELKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1389 AALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKEN 1468
Cdd:COG1196    267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1469 KSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMdrsllenqslsgscESLKLALEGL 1548
Cdd:COG1196    347 EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL--------------EELEEAEEAL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1549 TEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKE 1628
Cdd:COG1196    413 LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1629 TEKQLQEAEKEMEEMKEKMRKFAKSKQQKILEL----------------EEENDRLRAEVHPAGGTAKECMETLLSSNAS 1692
Cdd:COG1196    493 LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvavligveaayeaaleAALAAALQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1693 MKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEAT--EKHDNQMNVTEEATQSIPGETEDQD 1770
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtlVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1771 SLSMSTRPACSESVPSENSANPAVSEDVSShdeinnylQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKD 1850
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELE--------ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1622909132 1851 GELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERL 1895
Cdd:COG1196    725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2088-2925 2.39e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.10  E-value: 2.39e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2088 KDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTV----AQLAAFTK 2161
Cdd:TIGR02168  153 KPEERRAIFEEAAgiSKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAelreLELALLVL 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2162 SMSSLQDDRDRVIDEAKKWERKFSDA---IQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQ 2238
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELtaeLQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2239 TEVQLQQKVCDTLQgenkELLSQLEETrhlyhnsQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADI 2318
Cdd:TIGR02168  313 NLERQLEELEAQLE----ELESKLDEL-------AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2319 QNSKFSYEQLETDLQASRELTSRLHEEINMKEQKmisllsgKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENivlee 2398
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDR-------RERLQQEIEELLKKLEEAELKELQAELEELEEEL----- 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2399 enKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsvilekdqlIQEAAAENNKLK 2478
Cdd:TIGR02168  450 --EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG------------FSEGVKALLKNQ 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2479 EEIRGLRSHMDDLNSENAKLDAEL-IQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQR 2557
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2558 SSNALQEEKRDLSKEIESLKVSVS--------------------QLTRQVTALQEEGTLgIYHAQLKVKEEELQRLSALl 2617
Cdd:TIGR02168  596 NIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldnalelakKLRPGYRIVTLDGDL-VRPGGVITGGSAKTNSSIL- 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2618 sSSQKRITELEEELvcvqkeaaKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKD 2697
Cdd:TIGR02168  674 -ERRREIEELEEKI--------EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2698 LTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSE-TTFSMDLPEENS-----LS 2771
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAlDELRAELTLLNEeaanlRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2772 YLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFrksEEGKQRSAAQPATSLAEVQSLKK 2851
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL---LNERASLEEALALLRSELEELSE 901

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909132 2852 AMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQE-----YQDKTKTFQIMQEELRQENLSWQHELHQLRME 2925
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseeYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1807-2333 5.32e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 5.32e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1807 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEE 1886
Cdd:COG1196    230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1887 EKDDLE---ERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKI 1963
Cdd:COG1196    310 RRRELEerlEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1964 QGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQ 2043
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2044 AELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALRR 2119
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2120 EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKE 2199
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2200 ENC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNS 2272
Cdd:COG1196    630 ARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909132 2273 QNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQ 2333
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 154-988 1.76e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.02  E-value: 1.76e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  154 QQLQEKEELISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 233
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  234 EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKME---LEVAERKLSFHNLQEE 310
Cdd:TIGR02168  283 IEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEeklEELKEELESLEAELEE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  311 MRHLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQ-TI 389
Cdd:TIGR02168  363 LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQaEL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  390 EQLEDQLQQKSKEISQFLNRLPLQQHEtasqtcfpdvynegtqavteenIASLQKRVVELENEKGALLLSSIELEELKAE 469
Cdd:TIGR02168  443 EELEEELEELQEELERLEEALEELREE----------------------LEEAEQALDAAERELAQLQARLDSLERLQEN 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  470 NEKLSSQI-TLLEAQNRIGEADREVSEISIVDDANKRSSST--EESGQDVLENTFSQKHKELSVLLlemKEAQEEIAFLK 546
Cdd:TIGR02168  501 LEGFSEGVkALLKNQSGLSGILGVLSELISVDEGYEAAIEAalGGRLQAVVVENLNAAKKAIAFLK---QNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  547 LQLQGKRAEEGDHEVLdQKEMKQMEGEGIAPIKMEVFLEDTGQNFplmpneESSLPAVEKEQASTEHQNRTSEEISLNDA 626
Cdd:TIGR02168  578 LDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  627 GVELKS-----TKQDCDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNA 701
Cdd:TIGR02168  651 DGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  702 DNNSSAFTALSEERDQLLAQVKELSvvtelrAQVRQLEMNLAEAERQRrfdyesqtahhNLLTEQIHSLSIEAKSKDVKI 781
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  782 EVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETL 861
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  862 QQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspa 938
Cdd:TIGR02168  865 EELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--- 941

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622909132  939 glisKEELQHEFDLLKKENEQRKRKLQAALinrKELLQRVSRLEEELANL 988
Cdd:TIGR02168  942 ----QERLSEEYSLTLEEAEALENKIEDDE---EEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 291-1002 2.56e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 2.56e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  291 EKMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQAELESRYSALEQKHkaemEEKTSHILSLQKTGQELQSACDALKdq 370
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL----EELRLEVSELEEEIEELQKELYALA-- 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  371 nsKLLQDKDEQAVQSAQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQtcfpdvynEGTQAVTEENIASLQKRVVELE 450
Cdd:TIGR02168  295 --NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL--------EEKLEELKEELESLEAELEELE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  451 NEKGALLLSSIELEE-----------LKAENEKLSSQITLLEAQ-NRI-GEADREVSEISIVDDANKRSSSTEESGQ-DV 516
Cdd:TIGR02168  365 AELEELESRLEELEEqletlrskvaqLELQIASLNNEIERLEARlERLeDRRERLQQEIEELLKKLEEAELKELQAElEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  517 LENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAE------------------EGDHEVLDQKEMKQMEGEGIAP- 577
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERElaqlqarldslerlqenlEGFSEGVKALLKNQSGLSGILGv 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  578 ------------IKMEVFLEDTGQNfPLMPNEESSLPAVE---------------KEQASTEHQNRTSEEISLNDAGVEL 630
Cdd:TIGR02168  525 lselisvdegyeAAIEAALGGRLQA-VVVENLNAAKKAIAflkqnelgrvtflplDSIKGTEIQGNDREILKNIEGFLGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  631 KSTKQDCDKSLSAV--PDIGQCH----QDELERLKSQILELELNFHKAQEIY-------------EKNLDEKAKEISNLN 691
Cdd:TIGR02168  604 AKDLVKFDPKLRKAlsYLLGGVLvvddLDNALELAKKLRPGYRIVTLDGDLVrpggvitggsaktNSSILERRREIEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  692 QLIEEFKKNADNNSSAFTALSEERDQLLAQVKEL-SVVTELRAQVRQLEMNLAEAERQrrfdyesqtahHNLLTEQIHSL 770
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLrKELEELSRQISALRKDLARLEAE-----------VEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  771 SIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQL 850
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  851 LLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQ 930
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEELSEELRE 905

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622909132  931 NYDEMSpagliskeELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESE 1002
Cdd:TIGR02168  906 LESKRS--------ELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 778-1563 5.58e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.49  E-value: 5.58e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  778 DVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEvLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEkkRD 857
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLKEKEALERQKEAIE--RQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  858 VETLQQTIEEKDQQVTEISFSMTEKMVQLNE-----------EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVS 926
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEElnkkikdlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  927 GLKQNYDEMspagLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSK---KEIPLSESER 1003
Cdd:TIGR02169  326 KLEAEIDKL----LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKdyrEKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1004 GEVEEDKENKEYSEKCVTSKCQEIEI---SLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLL 1080
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAaiaGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1081 QAEISENQVIIQKL----TTSNTDASDGDSVALVKETVVISPPGTDSgehwkpEL----EEKILALEK-----------E 1141
Cdd:TIGR02169  482 EKELSKLQRELAEAeaqaRASEERVRGGRAVEEVLKASIQGVHGTVA------QLgsvgERYATAIEVaagnrlnnvvvE 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1142 KEQLQKKLQEALTSRKA------ILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKE--NENIGDQL--------RQL 1205
Cdd:TIGR02169  556 DDAVAKEAIELLKRRKAgratflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafKYVFGDTLvvedieaaRRL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1206 QIQVRE-SIDGKLPSPDQqewcSPTPGLEEPLFKATEQHHTQPVLESnLCPDWPSHSEDASALQGGTS-----VAQIKAQ 1279
Cdd:TIGR02169  636 MGKYRMvTLEGELFEKSG----AMTGGSRAPRGGILFSRSEPAELQR-LRERLEGLKRELSSLQSELRrienrLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1280 LKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHlREL 1359
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA-RLS 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1360 QPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQ---LEMQAKEHDERIKQLQVELCEMKQK 1436
Cdd:TIGR02169  790 HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQridLKEQIKSIEKEIENLNGKKEELEEE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1437 PEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGR------- 1509
Cdd:TIGR02169  870 LEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipee 949

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 1510 ---LALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLK 1563
Cdd:TIGR02169  950 elsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1134-1957 1.16e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 1.16e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1134 KILALEKEKEQLQKKLQEALTSRKAILKKAQEKErhlrEELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREsI 1213
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI-L 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1214 DGKLPSPDQQEwcsptpgleEPLFKATEQHHTQPVLESNLCPDWPSHSEDASAlqggtSVAQIKAQLKEIETEKEKLELK 1293
Cdd:TIGR02168  308 RERLANLERQL---------EELEAQLEELESKLDELAEELAELEEKLEELKE-----ELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1294 ISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEhLRELQPELDELQKLISEK 1373
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE-LKELQAELEELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1374 EEDVSYLSGQLREKEAALTKIQTEIieqedlikalhTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEEsrAKQQIQRK 1453
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQAL-----------DAAERELAQLQARLDSLERLQENLEGFSEGVKAL--LKNQSGLS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1454 LQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKdrvLGRLAL--LQEERDKLITEMDRSLLEN 1531
Cdd:TIGR02168  520 GILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNE---LGRVTFlpLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1532 QslsgscESLKLALEGLTEDKEKLVKEIESLKS-SKIAES-SEWQEKHKELQKEYEI------LLQSYENVSNEAERIQH 1603
Cdd:TIGR02168  597 I------EGFLGVAKDLVKFDPKLRKALSYLLGgVLVVDDlDNALELAKKLRPGYRIvtldgdLVRPGGVITGGSAKTNS 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1604 VVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAK---SKQQKILELEEENDRLRAEVhpagGTAK 1680
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKeleELSRQISALRKDLARLEAEV----EQLE 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1681 ECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEA--TEKHDNQMNVTEEA 1758
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAelTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1759 TQSIPGETEDQDSLSMSTRPACSESVPSEnSANPAVSEDVSSHDEINnylQQIDQLKERIAGLEEEKQKNKEFSQTLENE 1838
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIE-SLAAEIEELEELIEELE---SELEALLNERASLEEALALLRSELEELSEE 902

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1839 RNALLSQISTKDGELKLLQEEVSKMNL----LNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVT 1914
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELrlegLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1622909132 1915 DAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1957
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1539-2363 1.27e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 1.27e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1539 ESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQE---KHKELQKEYEILLQSYENVSNEAERIQhvveavrQEKQEL 1615
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRLE-------QQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1616 YGKLRSTEANKKETEKQLQEAekemeemkekmrkfakskQQKILELEEENDRLRAEVhpagGTAKECMETLLSSNASMKE 1695
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEEL------------------ESKLDELAEELAELEEKL----EELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1696 EVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEA------TEKHDNQMNVTEEATQSIPGETEDQ 1769
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDrrerlqQEIEELLKKLEEAELKELQAELEEL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1770 DSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAL------L 1843
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvL 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1844 SQISTKDGELKLLQEEV--------------SKMNLLNQQIQEELSRVTKLKETAEEEkDDLEERLMNQLAELNGSIGnY 1909
Cdd:TIGR02168  526 SELISVDEGYEAAIEAAlggrlqavvvenlnAAKKAIAFLKQNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG-V 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1910 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHA---------KELQ 1980
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1981 ELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASfkvlLDDTQSEA 2060
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTEL 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2061 ARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDK 2140
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2141 EIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWerkfSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELK 2220
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERASLEEALALLRSELEELSEELRELESKRSELR 914

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2221 INISRL-EHDKQIWESKAQTEVQLQQkvcdTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSN---- 2295
Cdd:TIGR02168  915 RELEELrEKLAQLELRLEGLEVRIDN----LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnla 990

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909132 2296 SLEKCKEQKENLEgIIRQQEADIQNSKFSYEQLETDLqaSRELTSRLHE---EINMKEQKMISLLSGKEEA 2363
Cdd:TIGR02168  991 AIEEYEELKERYD-FLTAQKEDLTEAKETLEEAIEEI--DREARERFKDtfdQVNENFQRVFPKLFGGGEA 1058
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1934-2755 2.04e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 2.04e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1934 VSELEEEKQQLVKEKTKVESEIRKEYL---EKIQGAQKEPGNKSHAKELQELLKEKQQ-EVKQLQKDCIRYQEKISALER 2009
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLiidEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2010 TVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAsfkvllDDTQSEAARVLADNLKLKKELQSNKESVKSQmKQKD 2089
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK------DLGEEEQLRVKEKIGELEAEIASLERSIAEK-EREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2090 EDLERRLEQAEE---KHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAF------- 2159
Cdd:TIGR02169  318 EDAEERLAKLEAeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYreklekl 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2160 TKSMSSLQDDRDRVIDEAKKWE-----------------RKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKIN 2222
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSeeladlnaaiagieakiNELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2223 ISRLEhDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESE-------------------- 2282
Cdd:TIGR02169  478 YDRVE-KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaagnrlnnvvved 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2283 -----------------------LNILKDQLTDLSNSLEK-CKEQKENLEGIIRQQEadiqnSKFSYEQLETDLQASREL 2338
Cdd:TIGR02169  557 davakeaiellkrrkagratflpLNKMRDERRDLSILSEDgVIGFAVDLVEFDPKYE-----PAFKYVFGDTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2339 TSRLHEEINM---------KEQKMI--SLLSGKEEAIQVAIAELRQQHDKEIKELENLLsqeeeenivleeenkkavdkt 2407
Cdd:TIGR02169  632 ARRLMGKYRMvtlegelfeKSGAMTggSRAPRGGILFSRSEPAELQRLRERLEGLKREL--------------------- 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2408 NQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsvilekdqlIQEAAAENNKLKEEIRGLRSH 2487
Cdd:TIGR02169  691 SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER-----------LEELEEDLSSLEQEIENVKSE 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2488 MDDLNSENAKLDAELIQYREDLNQvisikdsqqkqlLEAQL--QQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEE 2565
Cdd:TIGR02169  760 LKELEARIEELEEDLHKLEEALND------------LEARLshSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE 827

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2566 KRDLSKEIESLKVSVSQLTRQVTALQEE-----GTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELvcvqKEAAK 2640
Cdd:TIGR02169  828 KEYLEKEIQELQEQRIDLKEQIKSIEKEienlnGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL----RELER 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2641 KVGEIEDKLKKELKHLhhdaGIMRNETETAEERVAELARDLVEMEQKLLMVTKEnKDLTAQIQSFGRSMSSLQNSRDHAN 2720
Cdd:TIGR02169  904 KIEELEAQIEKKRKRL----SELKAKLEALEEELSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRALEPVNMLAI 978

                          890       900       910
                   ....*....|....*....|....*....|....*
gi 1622909132 2721 EELDELKRKYDaslkelaQLKEQQGLLNRERHALL 2755
Cdd:TIGR02169  979 QEYEEVLKRLD-------ELKEKRAKLEEERKAIL 1006
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1556-2383 7.30e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.56  E-value: 7.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1556 VKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVS---NEAERIQHVVEAVRQ-EKQELYGKLRSTEANKKETEK 1631
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRrerEKAERYQALLKEKREyEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1632 QLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKF 1711
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1712 QSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKhdnqmnvteeatqsipgetEDQDSLSMSTRPACSESVpsenSAN 1791
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYA-------------------ELKEELEDLRAELEEVDK----EFA 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1792 PAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQ 1871
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLA 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1872 EELSRVTKLKETAEEEKDDLEERLMN---QLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEk 1948
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKlqrELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATA- 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1949 tkveseirkeyLEKIQGAQKEP---GNKSHAKELQELLKEKQ---------QEVKQLQKDcIRYQEKISALERTVKALEF 2016
Cdd:TIGR02169  541 -----------IEVAAGNRLNNvvvEDDAVAKEAIELLKRRKagratflplNKMRDERRD-LSILSEDGVIGFAVDLVEF 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2017 VQTESQKDLEITKENLaqAVEHRKKAQAELASFK-VLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLErR 2095
Cdd:TIGR02169  609 DPKYEPAFKYVFGDTL--VVEDIEAARRLMGKYRmVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLE-G 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2096 LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQvtlnkkdKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2175
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE-------KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2176 EAKKWERKFSDaIQTKEEEIRLKEENC--SVLKDQLRQMSIHMEELKINISRLE----HDKQIWESKAQTEVQLQQKVcD 2249
Cdd:TIGR02169  759 ELKELEARIEE-LEEDLHKLEEALNDLeaRLSHSRIPEIQAELSKLEEEVSRIEarlrEIEQKLNRLTLEKEYLEKEI-Q 836

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2250 TLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLE 2329
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909132 2330 TDLQASRELTSRLHEEINMKEQKMISLLS-GKEEAIQVAIAELRQQHDKEIKELE 2383
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGEDEEiPEEELSLEDVQAELQRVEEEIRALE 971
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 727-1062 1.04e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 1.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  727 VVTELRAQVRQLEmnlAEAERQRRFdyesqtahhNLLTEQIHSLSIEAKSKdvKIEVLQNELDDVQLQFSEQSTLIRSLQ 806
Cdd:COG1196    194 ILGELERQLEPLE---RQAEKAERY---------RELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  807 SQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQL 886
Cdd:COG1196    260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  887 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDemspagliskEELQHEFDLLKKENEQRKRkLQA 966
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE----------ELAEELLEALRAAAELAAQ-LEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  967 ALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSekcvtskcQEIEISLKQTISEKEVELEHIR 1046
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL--------EEEEEALLELLAELLEEAALLE 476

                          330
                   ....*....|....*.
gi 1622909132 1047 KDLEEKMAAEEQLQAL 1062
Cdd:COG1196    477 AALAELLEELAEAAAR 492
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1976-2576 1.20e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 1.20e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1976 AKELQELLKEKQQEVKQLQKDciRYQEKISALERTVKALEfvqtesqkdleitkENLAQAVEHRKKAQAELASFKVLLDD 2055
Cdd:COG1196    215 YRELKEELKELEAELLLLKLR--ELEAELEELEAELEELE--------------AELEELEAELAELEAELEELRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2056 TQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV 2133
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERleELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2134 TLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRvideakkwerkfsdaIQTKEEEIRLKEENCSVLKDQLRQMS 2213
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2214 IHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDL 2293
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2294 SNSLE--KCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEInmkEQKMISLLSGKEEAiQVAIAEL 2371
Cdd:COG1196    504 EGFLEgvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEV---AAAAIEYLKAAKAG-RATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2372 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLnaikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQ 2451
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL----LGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2452 LEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDsQQKQLLEAQLQQN 2531
Cdd:COG1196    656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL-EEEALEEQLEAER 734

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1622909132 2532 KELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESL 2576
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2414-3157 1.54e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.39  E-value: 1.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2414 LNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSV---ILEKDQLIQEAAAENNKLKEEIRGLRSHMDD 2490
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELeeeIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2491 LNSENAKLDAELIQYREDLNQVISIKDSQQKQL------LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQE 2564
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2565 EKRDLSKEIESLKVSVSQLTRQVTALQEE-----------------GTLGIYHAQLKVKEEELQRLSALLSSSQKRITEL 2627
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2628 EEELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMV 2691
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2692 TKENKDLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSM 2762
Cdd:TIGR02168  554 NLNAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2763 DLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpats 2842
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEEL----------------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2843 LAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQL 2922
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2923 RMEKSSWEIHERRMKEQYLMAisDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRN 3002
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 3003 QLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNI 3082
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRR 915

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132 3083 DvapgapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSLAEEQIRRLE 3157
Cdd:TIGR02168  916 E-------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1421-2303 1.63e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.40  E-value: 1.63e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1421 ERIKQLQVELCEMKQKPEEIEEEsRAKQQIQRKLQAALISRK--EALKENKSLQEELSLARDTIEHLTKSLADVESHVSA 1498
Cdd:TIGR02169  184 ENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEgyELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1499 QNKEKDRVLGRLALLQEERDKLITEMDRSLLEN-QSLSGSCESLKLALEGLTEDKEKLVKEIESLKSskiaESSEWQEKH 1577
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSIAEKERELEDAEERLAKLEA----EIDKLLAEI 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1578 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQK 1657
Cdd:TIGR02169  339 EELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRL 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1658 ILELEEENDRLRAevhpaggtAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVS 1737
Cdd:TIGR02169  419 SEELADLNAAIAG--------IEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1738 KQANLEATEKHDNQMNVTEEATQSIPGETED------QDSLSMSTRPACSESVPSENSANPAVSEDVSShdeinnylqqi 1811
Cdd:TIGR02169  491 ELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvAQLGSVGERYATAIEVAAGNRLNNVVVEDDAV----------- 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1812 dqLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLqeevskMNLLNQQIQEELSRVTKLKETAEEEKDDL 1891
Cdd:TIGR02169  560 --AKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1892 EERLMNQ--LAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRkeyleKIQGAQKE 1969
Cdd:TIGR02169  632 ARRLMGKyrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELR-----RIENRLDE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1970 PgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASF 2049
Cdd:TIGR02169  707 L--SQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2050 KVLLDDTQSEAARVLADnlKLKKELQSNkESVKSQMKQKDEDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIG 2129
Cdd:TIGR02169  785 EARLSHSRIPEIQAELS--KLEEEVSRI-EARLREIEQKLNRLTLEKEYLE----KEIQELQEQRIDLKEQIKSIEKEIE 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2130 EIQVTLNKKDKEIQQVQenldstvAQLAAFTKSMSSLQDDRDRVIDEAKKWERKfsdaIQTKEEEIRLKEENCSVLKDQL 2209
Cdd:TIGR02169  858 NLNGKKEELEEELEELE-------AALRDLESRLGDLKKERDELEAQLRELERK----IEELEAQIEKKRKRLSELKAKL 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2210 RQMSIHMEELKINISRLEHDKQIWES--KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESElnilK 2287
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPEEELSleDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEE----R 1002

                          890
                   ....*....|....*.
gi 1622909132 2288 DQLTDLSNSLEKCKEQ 2303
Cdd:TIGR02169 1003 KAILERIEEYEKKKRE 1018
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1464-2057 2.10e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.01  E-value: 2.10e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1464 ALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMD---RSLLENQSLSGSCES 1540
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1541 LKLALEGLTEDKEKL---VKEIESLKSSKIAESSEWQEKHKELQ------KEYEIL---LQSYENVSNEAERIQHVVEAV 1608
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLsefYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1609 RQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskqQKILELEEENDRLRAEVhpaGGTAKECMETLLS 1688
Cdd:PRK03918   323 INGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY-----EEAKAKKEELERLKKRL---TGLTPEKLEKELE 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1689 SNASMKEEVERvkmEYETLSKKFQSLMSEKDSLSEEVQDLKHQleSNVSKQANLEATEKHdnQMNVTEEATQSIPGETED 1768
Cdd:PRK03918   395 ELEKAKEEIEE---EISKITARIGELKKEIKELKKAIEELKKA--KGKCPVCGRELTEEH--RKELLEEYTAELKRIEKE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1769 QDSLSMSTRPACSESVPSENSANPavSEDVSSHDEInnyLQQIDQLKERIAG--LEEEKQKNKEFSQTLEnernallsQI 1846
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKK--ESELIKLKEL---AEQLKELEEKLKKynLEELEKKAEEYEKLKE--------KL 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1847 STKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLESE 1926
Cdd:PRK03918   535 IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYNE 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1927 MKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKIS 2005
Cdd:PRK03918   604 YLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSRELA 676

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622909132 2006 ALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2057
Cdd:PRK03918   677 GLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 725-1456 2.13e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 2.13e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  725 LSVVTELRAQVRQLEMNLAEAERQ------RRFDYESQTAHHNLLTEQIhSLSIEAKSKDVKIEVlQNELDDVQLQFSEQ 798
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEEleklteEISELEKRLEEIEQLLEEL-NKKIKDLGEEEQLRV-KEKIGELEAEIASL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  799 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEisfs 878
Cdd:TIGR02169  307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE---- 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  879 MTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQnydemspagliSKEELQHEFDLLKKENE 958
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA-----------KINELEEEKEDKALEIK 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  959 QRKRKLQAALINRKELLQRVSRLEEELANLKD---QSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTI 1035
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKelsKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1036 SEKEvelehiRKDLEEKMAAEEQLQALVKEMNQTLQ-------------------DKTNQIDLLQAEISENQVIIQKLTT 1096
Cdd:TIGR02169  532 SVGE------RYATAIEVAAGNRLNNVVVEDDAVAKeaiellkrrkagratflplNKMRDERRDLSILSEDGVIGFAVDL 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1097 SNTDASDGDSVALV-KETVVIS-----------------------PPGT--------DSGEHWKPELEEKILALEKEKEQ 1144
Cdd:TIGR02169  606 VEFDPKYEPAFKYVfGDTLVVEdieaarrlmgkyrmvtlegelfeKSGAmtggsrapRGGILFSRSEPAELQRLRERLEG 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1145 LQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKlpsPDQQE 1224
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK---SELKE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1225 WCSPTPGLEEPLFKATEQhhtqpvlesnlcpdwpshSEDASALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKK 1304
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEA------------------LNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRL 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1305 SEEVFQLQDqinkqglEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE-HLRELQPELDELQKLISEKEEDVSYLSGQ 1383
Cdd:TIGR02169  825 TLEKEYLEK-------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQ 897

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622909132 1384 LREKEAALTKIQTEIIEQEDLIKALHTQLEMQAkehdERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQA 1456
Cdd:TIGR02169  898 LRELERKIEELEAQIEKKRKRLSELKAKLEALE----EELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2189-2740 2.49e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 2.49e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2189 QTKEEEIRLKEENCSVLKDQLRQMSIhmEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2268
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2269 YHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2348
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2349 KEQKMISLLSgKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQL 2428
Cdd:COG1196    370 AEAELAEAEE-ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2429 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAEN------------------NKLKEEIRGLRSHMDD 2490
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLllleaeadyegflegvkaALLLAGLRGLAGAVAV 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2491 LNSENAKLDAELIQYREDLNQVISIKDSQQ-KQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDL 2569
Cdd:COG1196    529 LIGVEAAYEAALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2570 SKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKL 2649
Cdd:COG1196    609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2650 KKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRK 2729
Cdd:COG1196    689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768

                          570
                   ....*....|.
gi 1622909132 2730 YDASLKELAQL 2740
Cdd:COG1196    769 LERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 652-1206 2.64e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 2.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  652 QDELERLKSQILELElnfhKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKelsvvtEL 731
Cdd:COG1196    238 EAELEELEAELEELE----AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------RL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  732 RAQVRQLEMNLAEAERQRrfdyESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN 811
Cdd:COG1196    308 EERRRELEERLEELEEEL----AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  812 KESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKF 891
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  892 SLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEF-------------DLLKKENE 958
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrglagavavligVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  959 QRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEK 1038
Cdd:COG1196    540 LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1039 EVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKEtvvisp 1118
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL------ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1119 pgtdsgehwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1198
Cdd:COG1196    694 -----------ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762


                   ....*...
gi 1622909132 1199 GDQLRQLQ 1206
Cdd:COG1196    763 EELERELE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2020-2631 4.61e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 4.61e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2020 ESQKDLEITKENLAQA----VEHRK-----KAQAELAsfkvllddtqsEAARVLADNLKLKK-ELQSNKESVKSQMKQKD 2089
Cdd:COG1196    176 EAERKLEATEENLERLedilGELERqleplERQAEKA-----------ERYRELKEELKELEaELLLLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2090 EDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAftksmssLQDD 2169
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE-------LEER 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2170 RDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2249
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2250 TLQgENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLE 2329
Cdd:COG1196    398 LAA-QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2330 TDLQASRELTSRLHEEINMKEQkMISLLSGKEEA------------IQVAIAELRQQHDKEIKELENLLSQEEEENIVLE 2397
Cdd:COG1196    477 AALAELLEELAEAAARLLLLLE-AEADYEGFLEGvkaalllaglrgLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2398 EENKKAV---DKTNQLM----ETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEA 2470
Cdd:COG1196    556 DEVAAAAieyLKAAKAGratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2471 AAENNKLKEEIRGLRSHMDDLNSENAKldaeliqyredlnqvISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEE 2550
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSL---------------TGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2551 ANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRlsallSSSQKRITELEEE 2630
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-----EELERELERLERE 775


                   .
gi 1622909132 2631 L 2631
Cdd:COG1196    776 I 776
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1273-1746 5.84e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 5.84e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1273 VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAG 1352
Cdd:COG1196    283 LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1353 LEH-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELC 1431
Cdd:COG1196    363 AEEaLLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1432 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSA-----QNKEKDRV 1506
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkaalLLAGLRGL 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1507 LGRLALLQEERDKLITEmDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEI 1586
Cdd:COG1196    523 AGAVAVLIGVEAAYEAA-LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1587 LLQSYENVsnEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEEND 1666
Cdd:COG1196    602 DLVASDLR--EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1667 RLRAEVhpaggtakecmETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATE 1746
Cdd:COG1196    680 ELEELA-----------ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2139-2910 6.59e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.47  E-value: 6.59e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2139 DKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERkfSDAIQTKEEEIRLKEencsvLKDQLRQMSIHMEE 2218
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYE-----LLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2219 LKINISRLEhdkqiwESKAQTEVQLQQKVCDTlqGENKELLSQLEEtrHLYHNSQNELAKLESELNILKDQLTDLSNSLE 2298
Cdd:TIGR02169  242 IERQLASLE------EELEKLTEEISELEKRL--EEIEQLLEELNK--KIKDLGEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2299 KCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSgKEEAIQVAIAELRQQHDKE 2378
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA-ELEEVDKEFAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2379 IKELENL-----------------LSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQND 2441
Cdd:TIGR02169  391 REKLEKLkreinelkreldrlqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2442 RDRIVGDYQQLEERhlsvILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENA---KLDAELIQYRED---------- 2508
Cdd:TIGR02169  471 LYDLKEEYDRVEKE----LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaag 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2509 --LNQVISIKDSQQKQLLEAQLQQNK----------------------------------ELKNKYAKLEEKLKESEEAN 2552
Cdd:TIGR02169  547 nrLNNVVVEDDAVAKEAIELLKRRKAgratflplnkmrderrdlsilsedgvigfavdlvEFDPKYEPAFKYVFGDTLVV 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2553 EDLQrSSNALQEEKRDLSKEIESLKVS-------VSQLTRQVTALQEEGTLgiyhAQLKVKEEELQRLSALLSSSQKRIT 2625
Cdd:TIGR02169  627 EDIE-AARRLMGKYRMVTLEGELFEKSgamtggsRAPRGGILFSRSEPAEL----QRLRERLEGLKRELSSLQSELRRIE 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2626 ELEEELVCVQKEAAKKVGEIEDklkkelkhlhhDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSF 2705
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEK-----------EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2706 GRSMSSLQnsrdhanEELDELKRKYDASlkelaQLKEQQGLlnrerhallsettfsmdlpeenslsyLEKLNQQLLSKDE 2785
Cdd:TIGR02169  771 EEDLHKLE-------EALNDLEARLSHS-----RIPEIQAE--------------------------LSKLEEEVSRIEA 812

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2786 QLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQ----SLKKAMSSLQNDRD 2861
Cdd:TIGR02169  813 RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEaalrDLESRLGDLKKERD 892

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1622909132 2862 RLLKELKNLQQQYLQINQEITELRPLKAQLQEyqdktkTFQIMQEELRQ 2910
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKKRKRLSELKA------KLEALEEELSE 935
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1353-2264 7.29e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 7.29e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1353 LEHLRELQPELDELQKLISEKEEDVSYLSGQlREKEAALTKIQTEIIEQEDLIKALhtqlemQAKEHDERIKQLQVELCE 1432
Cdd:TIGR02169  176 LEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLK------EKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1433 MKQKPEEIEEEsraKQQIQRKLQAALISRKEALKENKSLQEELSLA-RDTIEHLTKSLADVESHVSAQNKEKDRVLGRLA 1511
Cdd:TIGR02169  249 LEEELEKLTEE---ISELEKRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1512 LLQEERDKLITEMdrsllenqslsgsceslklalegltedkEKLVKEIESLKSSKIAesseWQEKHKELQKEYEILLQSY 1591
Cdd:TIGR02169  326 KLEAEIDKLLAEI----------------------------EELEREIEEERKRRDK----LTEEYAELKEELEDLRAEL 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1592 ENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANkketEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1671
Cdd:TIGR02169  374 EEVDKEFAETRDELKDYREKLEKLKREINELKRE----LDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1672 VhpaggtakECMETLLSSNASMKEEVERvkmEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKhdnq 1751
Cdd:TIGR02169  450 I--------KKQEWKLEQLAADLSKYEQ---ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEE---- 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1752 mnVTEEATQSIPGETEDQDSLSMSTRPACsESVPSENSANPAVSEDVSShdeinnylqqidqlKERIAGLEEEKQKNKEF 1831
Cdd:TIGR02169  515 --VLKASIQGVHGTVAQLGSVGERYATAI-EVAAGNRLNNVVVEDDAVA--------------KEAIELLKRRKAGRATF 577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1832 SQTLENERNALLSQISTKDGELKLLqeevskMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQ--LAELNGSIGNY 1909
Cdd:TIGR02169  578 LPLNKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKyrMVTLEGELFEK 651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1910 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEylekiqgaqkepgnKSHAKELQELLKEKQQE 1989
Cdd:TIGR02169  652 SGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI--------------ENRLDELSQELSDASRK 717

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1990 VKQLQKDciryqekISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASfkvllddtqseaarvladnlk 2069
Cdd:TIGR02169  718 IGEIEKE-------IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEE--------------------- 769

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2070 lkkelqsnKESVKSQMKQKDEDLERRLEQaeekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2149
Cdd:TIGR02169  770 --------LEEDLHKLEEALNDLEARLSH------SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI 835

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2150 DSTVAQLAAFTKSMSSLQDDrdrvIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHD 2229
Cdd:TIGR02169  836 QELQEQRIDLKEQIKSIEKE----IENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1622909132 2230 KQIWESK-AQTEVQLQqkvcdTLQGENKELLSQLEE 2264
Cdd:TIGR02169  912 IEKKRKRlSELKAKLE-----ALEEELSEIEDPKGE 942
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 654-1100 7.83e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.14  E-value: 7.83e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  654 ELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKElsvvtelra 733
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHK--------- 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  734 qvRQLEMNLAEAERQRRFDYESQTAhhnllteqihslsieakskdVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKE 813
Cdd:pfam15921  389 --REKELSLEKEQNKRLWDRDTGNS--------------------ITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  814 SEVL-------EGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQL 886
Cdd:pfam15921  447 ERQMaaiqgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSR 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  887 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMS--------PAGLISKEELQ----------- 947
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTqlvgqhgrTAGAMQVEKAQlekeindrrle 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  948 -HEFDLLKKENEQRKRKLQAALINRK-ELLQRVSRLEEELANLKDQSKKEIPL---SESERGEVEEDKENKEYSEKCVTS 1022
Cdd:pfam15921  606 lQEFKILKDKKDAKIRELEARVSDLElEKVKLVNAGSERLRAVKDIKQERDQLlneVKTSRNELNSLSEDYEVLKRNFRN 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1023 KCQEIEIS---LKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEIsenQVIIQKLTTSNT 1099
Cdd:pfam15921  686 KSEEMETTtnkLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI---QFLEEAMTNANK 762


                   .
gi 1622909132 1100 D 1100
Cdd:pfam15921  763 E 763
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1958-2827 8.27e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 8.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1958 EYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKD---CIRYQEKISALErtvkalEFVQTESQKDLEITKENLA 2033
Cdd:TIGR02169  167 EFDRKKEKALEELEEvEENIERLDLIIDEKRQQLERLRRErekAERYQALLKEKR------EYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2034 QAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKhLKEKKNMQEK 2113
Cdd:TIGR02169  241 AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERS-IAEKERELED 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2114 LDALRREkvhLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEE 2193
Cdd:TIGR02169  320 AEERLAK---LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2194 EIRLKEE---NCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAqtevqlqqkvcDTLQGENKELLSQLEETRHLYH 2270
Cdd:TIGR02169  397 LKREINElkrELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEK-----------EDKALEIKKQEWKLEQLAADLS 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2271 NSQNELAKLESELNILKDQLTDLSNSLEKCKEQKenlegiiRQQEADIQNSKFSYEQLETDLQASRELTSRLheeINMKE 2350
Cdd:TIGR02169  466 KYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA-------RASEERVRGGRAVEEVLKASIQGVHGTVAQL---GSVGE 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2351 QKMISL---LSGKEEAIQV--------AIAELRQQHD--------KEIKELENLLSQEEEENIVLEEENKKAVDKTNQ-- 2409
Cdd:TIGR02169  536 RYATAIevaAGNRLNNVVVeddavakeAIELLKRRKAgratflplNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEpa 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2410 ---------LMETLNAIKKENIQQKA---QLDSFVKS--MSSLQNDRDRIVGDYQQLEERHLSVILEKDQLiqeaAAENN 2475
Cdd:TIGR02169  616 fkyvfgdtlVVEDIEAARRLMGKYRMvtlEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGL----KRELS 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2476 KLKEEIRGLRSHMDdlnsenakldaELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLeeklkeseeanEDL 2555
Cdd:TIGR02169  692 SLQSELRRIENRLD-----------ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL-----------SSL 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2556 QRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQ 2635
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEAR----LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLT 825

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2636 KEAakkvgEIEDKLKKELKHLHHDAGIMRNETETAEE----RVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSS 2711
Cdd:TIGR02169  826 LEK-----EYLEKEIQELQEQRIDLKEQIKSIEKEIEnlngKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2712 LQNsrdhaneELDELKRKYDASLKELAQLKEQQGLLNRERHALlsETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLS 2791
Cdd:TIGR02169  901 LER-------KIEELEAQIEKKRKRLSELKAKLEALEEELSEI--EDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALE 971

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|...
gi 1622909132 2792 S-------QLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRK 2827
Cdd:TIGR02169  972 PvnmlaiqEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1384-1903 1.13e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 64.29  E-value: 1.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1384 LREKEAALTKIQTEI--IEQEDLIKALHTqLEMQAKEHDERIKQLQVE---LCEMKQKPEEIEEESRAKQQIQRKLQAAL 1458
Cdd:PRK02224   182 LSDQRGSLDQLKAQIeeKEEKDLHERLNG-LESELAELDEEIERYEEQreqARETRDEADEVLEEHEERREELETLEAEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1459 ----ISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSL 1534
Cdd:PRK02224   261 edlrETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1535 SGSCESLK---LALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQE 1611
Cdd:PRK02224   341 NEEAESLRedaDDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1612 KQELYGKLRSTEANKKETEKQLQEAEKEMEE----------MKEKMRKFAKSKQQKILELEEENDRLRAEVhpaggtake 1681
Cdd:PRK02224   421 RDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEV--------- 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1682 cmetllssnASMKEEVERVKMEYETlSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANL-EATEKHDNQMNVTEEATQ 1760
Cdd:PRK02224   492 ---------EEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRETIEEKRERAEELrERAAELEAEAEEKREAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1761 SIPGETEDqdslSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEekqknkefsqtLENERN 1840
Cdd:PRK02224   562 EAEEEAEE----AREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAE-----------LNDERR 626

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909132 1841 ALLSQISTKDGEL--KLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER---LMNQLAELN 1903
Cdd:PRK02224   627 ERLAEKRERKRELeaEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELE 694
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 9-894 1.17e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 1.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132    9 EDVQERLAYAEQLVVELKDIIRQKDVQLqqkdEALQEEKKAADNKIKKLKLHAKAKLTSLNKHIEEMKAQGGTVLLTEPQ 88
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQL----KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132   89 SEEQLSKHDKSSTEEEMEVEKIKHKLQEKEEQIstlqaqltqaqAEQAAQFDKSSTEMKEFVMMKQQLQEKEELISTLQA 168
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEI-----------EELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  169 QLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHeeslvgRAQVVDLLQ 248
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL------RSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  249 QELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQAEL 328
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  329 ESRYSALEQKHKAEMEEKTShILSLQKTGQELQSACDALKDQNSKLLQD------------KDEQAVQSA--QTIEQLED 394
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGIlgvlselisvdeGYEAAIEAAlgGRLQAVVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  395 QLQQKSKEISQFlnrlpLQQHETASQTCFPdvynegtqaVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLS 474
Cdd:TIGR02168  553 ENLNAAKKAIAF-----LKQNELGRVTFLP---------LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAL 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  475 SQI--------TLLEAQNRIGEADREVSEISIVDD-ANKRSSSTEESGQDVLeNTFSQKhKELSVLLLEMKEAQEEIAFL 545
Cdd:TIGR02168  619 SYLlggvlvvdDLDNALELAKKLRPGYRIVTLDGDlVRPGGVITGGSAKTNS-SILERR-REIEELEEKIEELEEKIAEL 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  546 KLQLQgkRAEEGDHEVLDQKEMKQMEGEGIapikmevfledtgqnfplmpNEESSLPAVEKEQASTEHQNRTSEEISLnd 625
Cdd:TIGR02168  697 EKALA--ELRKELEELEEELEQLRKELEEL--------------------SRQISALRKDLARLEAEVEQLEERIAQL-- 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  626 agvelkstkqdcdkslsavpdigqchQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNS 705
Cdd:TIGR02168  753 --------------------------SKELTELEAEIEELEERLEEAEE----ELAEAEAEIEELEAQIEQLKEELKALR 802

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  706 SAFTALSEERDQLLAQvkelsvVTELRAQVRQLEMNLAEAERQRRfDYESQTAHhnlLTEQIHSLSIEAKSKDVKIEVLQ 785
Cdd:TIGR02168  803 EALDELRAELTLLNEE------AANLRERLESLERRIAATERRLE-DLEEQIEE---LSEDIESLAAEIEELEELIEELE 872

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  786 NELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKR----DVETL 861
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLT 952

                          890       900       910
                   ....*....|....*....|....*....|...
gi 1622909132  862 QQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLG 894
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRLENKIKELG 985
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2332-3156 1.47e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 1.47e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2332 LQASRELTSRLHEEINMKEQKMISLLSG-------KEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAV 2404
Cdd:TIGR02168  205 LERQAEKAERYKELKAELRELELALLVLrleelreELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIE 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2405 DKTNQLMETLNAIKKENiQQKAQLDsfvKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQL---IQEAAAENNKLKEEI 2481
Cdd:TIGR02168  285 ELQKELYALANEISRLE-QQKQILR---ERLANLERQLEELEAQLEELESKLDELAEELAELeekLEELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2482 RGLRSHMDDLNSENAKLDAELIQYREDLNQVisikdSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDlQRSSNA 2561
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSKVAQL-----ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK-KLEEAE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2562 LQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyHAQLKVKEEELQRLSALLSSSQKRITELEEelvcvQKEAAKK 2641
Cdd:TIGR02168  435 LKELQAELEELEEELEELQEELERLEEALEEL------REELEEAEQALDAAERELAQLQARLDSLER-----LQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2642 VGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQ---SFGRSMSSLQNSRDH 2718
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLkqnELGRVTFLPLDSIKG 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2719 A-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLSS 2792
Cdd:TIGR02168  584 TeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGG 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2793 QLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpatsLAEVQSLKKAMSSLQNDRDRLLKELKNLQQ 2872
Cdd:TIGR02168  660 VI---TGGSAKTNSSILERRREIEELEEKIEEL-----------------EEKIAELEKALAELRKELEELEEELEQLRK 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2873 QYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAisDKDQQVS 2952
Cdd:TIGR02168  720 ELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA--QIEQLKE 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2953 HLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEK 3032
Cdd:TIGR02168  797 ELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 3033 NTLSIQLcdtsqslrenqqhygdllnhcAVLEKQVQELQavskekgplnidvapgapqekngvhrksdpEELREPQQSFS 3112
Cdd:TIGR02168  869 EELESEL---------------------EALLNERASLE------------------------------EALALLRSELE 897

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1622909132 3113 EAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSLAEEQIRRL 3156
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1037-1893 1.51e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 1.51e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1037 EKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDAsDGDSVALVKEtvvi 1116
Cdd:TIGR02168  222 LRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL-QKELYALANE---- 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1117 sppgtdsgehwKPELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENE 1196
Cdd:TIGR02168  297 -----------ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1197 NIGDQLRQLQIQVREsidgklpspDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsEDASALQGGTSVAQI 1276
Cdd:TIGR02168  362 ELEAELEELESRLEE---------LEEQLETLRSKVAQLELQIASLNNEIERLEARL--------ERLEDRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1277 KAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQlqiAGLEHL 1356
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE---RLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1357 RELQPELDELQKLISEKEEDVSYLSGQLR---EKEAALtkiqtEIIEQEDLIKALHTQLE--MQAKEHDERIKQLQVELC 1431
Cdd:TIGR02168  502 EGFSEGVKALLKNQSGLSGILGVLSELISvdeGYEAAI-----EAALGGRLQAVVVENLNaaKKAIAFLKQNELGRVTFL 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1432 EMKQKPEeieeesrakQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKD-RVLGRL 1510
Cdd:TIGR02168  577 PLDSIKG---------TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKlRPGYRI 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1511 ALLQEE---RDKLIT----EMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKE 1583
Cdd:TIGR02168  648 VTLDGDlvrPGGVITggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1584 YEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEE 1663
Cdd:TIGR02168  728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1664 ENDRLRAevhpaggtakecmetLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLE 1743
Cdd:TIGR02168  808 LRAELTL---------------LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1744 -ATEKHDNQMNVTEEATQSIpgeTEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAgle 1822
Cdd:TIGR02168  873 sELEALLNERASLEEALALL---RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS--- 946

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909132 1823 EEKQKNKEFSQTLENERNALLSQIstkDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEE 1893
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2450-3021 1.91e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 1.91e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2450 QQLEERHLSVILEKDQLIQEAAAEnnkLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQvisikdsqQKQLLEAQLQ 2529
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEE---LEAELEELEAELEELEAELAELEAELEELRLELEE--------LELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2530 QNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKEEE 2609
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE--LEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2610 LQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDkLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLL 2689
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2690 MVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQgllnRERHALLSETTFSMDLPEENS 2769
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE----ADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2770 LSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSL 2849
Cdd:COG1196    522 LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2850 KKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTK------TFQIMQEELRQENLSWQHELHQLR 2923
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLegeggsAGGSLTGGSRRELLAALLEAEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2924 MEKSSWEIHERRMKEQYLMAISDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASPETSASPDGSQNLIYETELLRNQ 3003
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                          570
                   ....*....|....*...
gi 1622909132 3004 LNDSLKEIHQKELRIQQL 3021
Cdd:COG1196    762 LEELERELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 1872-2497 2.39e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.62  E-value: 2.39e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1872 EELSRVTKLKETAEEEKDDLEER---LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE--EEKQQLVK 1946
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERnneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKkaEEKKKADE 1306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1947 EKTKVESEIRKEYLEKiqgaqKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLE 2026
Cdd:PTZ00121  1307 AKKKAEEAKKADEAKK-----KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD 1381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2027 ITK---ENLAQAVEHRKKAQAELASFKVLlddTQSEAARVLADNLKLKKELQSNKESVK--SQMKQKDEDLERRLEQAEE 2101
Cdd:PTZ00121  1382 AAKkkaEEKKKADEAKKKAEEDKKKADEL---KKAAAAKKKADEAKKKAEEKKKADEAKkkAEEAKKADEAKKKAEEAKK 1458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2102 -KHLKEKKNMQEKLDALRR---EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQD-DRDRVIDE 2176
Cdd:PTZ00121  1459 aEEAKKKAEEAKKADEAKKkaeEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaEEAKKADE 1538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2177 AKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENK 2256
Cdd:PTZ00121  1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2257 ----ELLSQLEETRHLYHNSQN----------ELAKLESELNILKDQLTdlsnslEKCKEQKENLEGIiRQQEADIQNSK 2322
Cdd:PTZ00121  1619 kikaEELKKAEEEKKKVEQLKKkeaeekkkaeELKKAEEENKIKAAEEA------KKAEEDKKKAEEA-KKAEEDEKKAA 1691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2323 FSYEQLETDLQASRELTSRLHEEINMKEQkmislLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKK 2402
Cdd:PTZ00121  1692 EALKKEAEEAKKAEELKKKEAEEKKKAEE-----LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2403 AVDKTNQLMETLNAIK----KENIQQKAQLDSFVKSMSSL-------QNDRDRIVGDYQQLEerhlsvilekDQLIQEAA 2471
Cdd:PTZ00121  1767 EKKAEEIRKEKEAVIEeeldEEDEKRRMEVDKKIKDIFDNfaniiegGKEGNLVINDSKEME----------DSAIKEVA 1836

                          650       660
                   ....*....|....*....|....*.
gi 1622909132 2472 AENNKLKEEIRGLRSHMDDLNSENAK 2497
Cdd:PTZ00121  1837 DSKNMQLEEADAFEKHKFNKNNENGE 1862
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1811-2593 4.46e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 4.46e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1811 IDQLKERIAGLEEEKQKNKEFSQTLE-----------NERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTK 1879
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKekreyegyellKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1880 LKETAEEEKDDLEERLMNQLaelngsignycqdvtdaQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEy 1959
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1960 lekiqgaqkepgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKENLAQAVEHR 2039
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD-------KEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2040 KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKsQMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRR 2119
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWK----LEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2120 EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRV---IDEAKKWERKFSDAIQT------ 2190
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVaagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2191 -----------KEEEIRLKEENCS--------VLKDQLRQMSIHMEE--LKINISRLEHDKQ-------------IWESK 2236
Cdd:TIGR02169  550 nnvvveddavaKEAIELLKRRKAGratflplnKMRDERRDLSILSEDgvIGFAVDLVEFDPKyepafkyvfgdtlVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2237 AQTEVQLQQKVCDTLQGENKE----LLSQLEETRHLYHNSQNELAKLESelniLKDQLTDLSNSLEKCKEQKENLEGIIR 2312
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEksgaMTGGSRAPRGGILFSRSEPAELQR----LRERLEGLKRELSSLQSELRRIENRLD 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2313 QQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKmislLSGKEEAIQVAIAELrQQHDKEIKELEnllsqeeee 2392
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED----LSSLEQEIENVKSEL-KELEARIEELE--------- 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2393 nivleeenkkavDKTNQLMETLNAIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQL---IQE 2469
Cdd:TIGR02169  772 ------------EDLHKLEEALNDLEARLSHS--RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2470 AAAENNKLKEEIRGLRSHMDDLNSENAKLDAELiqyredlnqvisikdsqqkqlleaqlqqnKELKNKYAKLEEKLKESE 2549
Cdd:TIGR02169  838 LQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL-----------------------------EELEAALRDLESRLGDLK 888

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1622909132 2550 EANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEE 2593
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1809-2015 4.51e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 61.32  E-value: 4.51e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1809 QQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEK 1888
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1889 DDLEERLMNQLAEL--NGSIGNY-----CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEiRKEYLE 1961
Cdd:COG4942    100 EAQKEELAELLRALyrLGRQPPLalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE-RAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622909132 1962 KIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALE 2015
Cdd:COG4942    179 LLAELEEE------RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1802-2576 5.42e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 5.42e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1802 DEINNYLQQIDQLKERIAGLEEEKQKN-KEFSQTLENERNALLSQISTKDGELKLLQEEVSKmnlLNQQIQEELSRVTKL 1880
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAK---LEAEIDKLLAEIEEL 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1881 KETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYL 1960
Cdd:TIGR02169  342 EREIEEERKRRDK-LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1961 EKIQGAQKEPGNKSHAKELQELLKEKQQEVK-------QLQKDCIRYQEKISALERTVKALEFVQTESQKDLEItKENLA 2033
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEEEKEDKALEIKkqewkleQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE-AEAQA 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2034 QAVEHRkkaQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ----KDEDL---------ERRLEQAE 2100
Cdd:TIGR02169  500 RASEER---VRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvvEDDAVakeaiellkRRKAGRAT 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2101 EKHLKEKKNMQEKLDALRREKVHleetigEIQVTLNKKDKEIQQVqenldstVAQLAAFTKSMSSLQDDRDRVID----- 2175
Cdd:TIGR02169  577 FLPLNKMRDERRDLSILSEDGVI------GFAVDLVEFDPKYEPA-------FKYVFGDTLVVEDIEAARRLMGKyrmvt 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2176 -EAKKWERkfSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWES---KAQTEVQLQQKVCDTL 2251
Cdd:TIGR02169  644 lEGELFEK--SGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENrldELSQELSDASRKIGEI 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2252 QGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFsyEQLETD 2331
Cdd:TIGR02169  722 EKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRI--PEIQAE 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2332 LQASRELTSRLHEEINMKEQKMISLLSGKEEAiqvaiaelrqqhDKEIKELENLLsqeeEENIVLEEENKKAVDKTNQLM 2411
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYL------------EKEIQELQEQR----IDLKEQIKSIEKEIENLNGKK 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2412 ETLNAIKKENIQQKAQLDsfvKSMSSLQNDRDRIVGDYQQLEERhlsvilekdqlIQEAAAENNKLKEEIRGLRSHMDDL 2491
Cdd:TIGR02169  864 EELEEELEELEAALRDLE---SRLGDLKKERDELEAQLRELERK-----------IEELEAQIEKKRKRLSELKAKLEAL 929

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2492 NSENAKLDAELIQYREDLNQVISIKDSQQK-QLLEAQLQQNKELKNKyakLEEKLKESEEANEDLQRSSNALQEEKRDLS 2570
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIPEEELSLEDVQAElQRVEEEIRALEPVNML---AIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006


                   ....*.
gi 1622909132 2571 KEIESL 2576
Cdd:TIGR02169 1007 ERIEEY 1012
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 24-578 5.67e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 5.67e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132   24 ELKDIIRQKDVQLQ-QKDEALQEEKKAADNKIKKLKLHAKakltSLNKHIEEMKAQGGTVLLTEPQSEEQLSKHDKSSTE 102
Cdd:COG1196    217 ELKEELKELEAELLlLKLRELEAELEELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  103 EEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEmkefvmmKQQLQEKEELISTLQAQLSQTQAEQAAQLS 182
Cdd:COG1196    293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL-------EEELEELEEELEEAEEELEEAEAELAEAEE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  183 SMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESlvgRAQVVDLLQQELTAAEQRNQILS 262
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL---EEELEELEEALAELEEEEEEEEE 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  263 QQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLsfhNLQEEMRHLLEQLEQAGQAQAELESRySALEQKHKAE 342
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL---LEELAEAAARLLLLLEAEADYEGFLE-GVKAALLLAG 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  343 MEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAqtIEQLEDQ---------LQQKSKEISQFLNRLPLQ 413
Cdd:COG1196    519 LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA--IEYLKAAkagratflpLDKIRARAALAAALARGA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  414 QHETASQTCFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRIGEADREV 493
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  494 SEISIVDDANKRSSSTEESGQDVLENtfSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEGDHEVLDQKEMKQMEGE 573
Cdd:COG1196    677 AEAELEELAERLAEEELELEEALLAE--EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754


                   ....*
gi 1622909132  574 GIAPI 578
Cdd:COG1196    755 ELPEP 759
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 896-1496 7.62e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 7.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  896 EIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSpaglISKEELQHEFDLLKKENEQRKRKLQAALINRKELL 975
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELE----LELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  976 QRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEysekcvtskcQEIEISLKQTISEKEVELEHIRKDLEEKMAA 1055
Cdd:COG1196    316 ERLEELEEELAELEEELEEL----EEELEELEEELEEAE----------EELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1056 EEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKEtvvisppgtdsgehwkpELEEKI 1135
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE-----------------EEEEAL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1136 LALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1215
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1216 klpspdqqewcsptPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASalqggtsvAQIKAQLKEIETEKEKLELKIS 1295
Cdd:COG1196    525 --------------AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAA--------AAIEYLKAAKAGRATFLPLDKI 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1296 STTSELTKKSEEVFQLQDQINKQGLEIEslktASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEE 1375
Cdd:COG1196    583 RARAALAAALARGAIGAAVDLVASDLRE----ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1376 DVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelcemkqkpEEIEEESRAKQQIQRKLQ 1455
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA----------EAEEERLEEELEEEALEE 728

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1622909132 1456 AALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHV 1496
Cdd:COG1196    729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 881-1732 1.07e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.53  E-value: 1.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  881 EKMVQLNEEKFSLGVEIKTLKEQ-LNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagLISKEELQHEFDLLKKENEQ 959
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQeLKLKEQAKKALEYYQLKEKLELEEEYLLYLDY----LKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  960 RKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKE 1039
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1040 VELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPP 1119
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1120 G-TDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1198
Cdd:pfam02463  412 ElARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLS 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1199 GDQLRQLQIQVRESIDG--KLPSPDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDA-----SALQGGT 1271
Cdd:pfam02463  492 RQKLEERSQKESKARSGlkVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEveerqKLVRALT 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1272 SVAQIKAQLKEIETEKEKLELKISSTTSELT--------KKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKL 1343
Cdd:pfam02463  572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPIlnlaqldkATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1344 ESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERI 1423
Cdd:pfam02463  652 VSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQ 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1424 KQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEK 1503
Cdd:pfam02463  732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1504 DRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKE 1583
Cdd:pfam02463  812 EEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESK 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1584 YEillqsyenvsneaeriqhvvEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEE 1663
Cdd:pfam02463  892 EE--------------------KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKE 951

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909132 1664 ENDRLRAEVHPAGGTAKEcmETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQL 1732
Cdd:pfam02463  952 ENNKEEEEERNKRLLLAK--EELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1130-1728 1.34e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.34e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1130 ELEEKILALEKEKEQLQKKLQEALTSrkaiLKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQV 1209
Cdd:COG1196    271 ELRLELEELELELEEAQAEEYELLAE----LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1210 REsidgklpspdqqewcsptpglEEPLFKATEQHHTQpvlesnlcpdwpshsEDASALQGGTSVAQIKAQLKEIETEKEK 1289
Cdd:COG1196    347 EE---------------------AEEELEEAEAELAE---------------AEEALLEAEAELAEAEEELEELAEELLE 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1290 LELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAglEHLRELQPELDELQKL 1369
Cdd:COG1196    391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA--ELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1370 ISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAK-- 1447
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAal 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1448 QQIQRKLQAALISRKEALKENKslqeelsLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRS 1527
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAK-------AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1528 LLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEyeillqsyenvsnEAERIQHVVEA 1607
Cdd:COG1196    622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA-------------EAELEELAERL 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1608 VRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKEcmETLL 1687
Cdd:COG1196    689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL--EELE 766

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1622909132 1688 SSNASMKEEVER---VKM----EYETLSKKFQSLMSEKDSLSEEVQDL 1728
Cdd:COG1196    767 RELERLEREIEAlgpVNLlaieEYEELEERYDFLSEQREDLEEARETL 814
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2271-2742 1.55e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.80  E-value: 1.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2271 NSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE--EINM 2348
Cdd:TIGR04523  149 KKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISElkKQNN 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2349 KEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQL 2428
Cdd:TIGR04523  229 QLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDW 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2429 DSFVKSmsSLQNDRDRIVGDYQQLEERHLSVilekdqliqeaaaenNKLKEEIRGLRSHMDDLNSENAKLDAELiqyRED 2508
Cdd:TIGR04523  309 NKELKS--ELKNQEKKLEEIQNQISQNNKII---------------SQLNEQISQLKKELTNSESENSEKQREL---EEK 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2509 LNQVISIKDSQQKQLleaqlQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVT 2588
Cdd:TIGR04523  369 QNEIEKLKKENQSYK-----QEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIK 443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2589 ALQEEGTlgiyhaqlkVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETE 2668
Cdd:TIGR04523  444 DLTNQDS---------VKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK-EKELKKLNEEKKELEEKVK 513

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132 2669 TAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQS--FGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2742
Cdd:TIGR04523  514 DLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQE 589
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 524-1214 4.04e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 4.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  524 KHKELSVLLLEMKEAQEEIAFLKLQLqgKRAEEGDHEVLDQKEMKQMEGEGIapikmevfledtgqnfplmpneESSLPA 603
Cdd:TIGR02168  223 RELELALLVLRLEELREELEELQEEL--KEAEEELEELTAELQELEEKLEEL----------------------RLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  604 VEKEQAS-TEHQNRTSEEISlndagvELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYE----- 677
Cdd:TIGR02168  279 LEEEIEElQKELYALANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEelkee 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  678 -----KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV--------VTELRAQVRQLEMNLAE 744
Cdd:TIGR02168  353 lesleAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEArlerledrRERLQQEIEELLKKLEE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  745 AERQR-RFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKES------EVL 817
Cdd:TIGR02168  433 AELKElQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGfsegvkALL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  818 EGAERVRHISSKVEELSQALSQKELEIAK-----MDQLLLEKKRDVETLQQTIEEKDQ-QVTEISFSMTEKMVQLNEEKF 891
Cdd:TIGR02168  513 KNQSGLSGILGVLSELISVDEGYEAAIEAalggrLQAVVVENLNAAKKAIAFLKQNELgRVTFLPLDSIKGTEIQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  892 SLGVEIKTLKEQLNLLSRAEEAKK------------EQVEEDNEVVSGLKQNY-------DEMSPAGLISKEELQHEFDL 952
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvDDLDNALELAKKLRPGYrivtldgDLVRPGGVITGGSAKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  953 LK-----KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEI 1027
Cdd:TIGR02168  673 LErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1028 EISLKQTISEKEVELEHIRKDLEEKMAAE---EQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTtsNTDASDG 1104
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR--ERLESLE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1105 DSVALVKETVVISPPGTDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAI---LKKAQEKERHLREELKQQKDDY 1181
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLeeaLALLRSELEELSEELRELESKR 910

                          730       740       750
                   ....*....|....*....|....*....|...
gi 1622909132 1182 NRLQEQFDEQSKENENIGDQLRQLQIQVRESID 1214
Cdd:TIGR02168  911 SELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1804-2308 4.60e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.31  E-value: 4.60e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1804 INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNallsQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKET 1883
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEE----LIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1884 AEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQqlVKEKTKVESEIRKEYLEKI 1963
Cdd:PRK03918   233 LEELKEEIEE-LEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKE--KAEEYIKLSEFYEEYLDEL 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1964 QGAQKEPGN-KSHAKELQELLKE---KQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHR 2039
Cdd:PRK03918   310 REIEKRLSRlEEEINGIEERIKEleeKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2040 KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQmKQKDEDLERRLEQAEEKHL------------KEK 2107
Cdd:PRK03918   390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA-KGKCPVCGRELTEEHRKELleeytaelkrieKEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2108 KNMQEKLDALRREKVHLE----------------ETIGEIQVTLNKKDKE-IQQVQENLDSTVAQLAAFTKSMSSLQDDR 2170
Cdd:PRK03918   469 KEIEEKERKLRKELRELEkvlkkeseliklkelaEQLKELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLKGEIKSLKKEL 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2171 DRvIDEAKKWERKFSDAIQTKEEEI-----RLKEENCSVLKD------QLRQMSIHMEELKINISRLEHDKQIWES---- 2235
Cdd:PRK03918   549 EK-LEELKKKLAELEKKLDELEEELaellkELEELGFESVEEleerlkELEPFYNEYLELKDAEKELEREEKELKKleee 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2236 --KAQTEVQLQQKVCDTLQGENKELLSQLEETRH-----LYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLE 2308
Cdd:PRK03918   628 ldKAFEELAETEKRLEELRKELEELEKKYSEEEYeelreEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1856-2462 6.50e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.54  E-value: 6.50e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1856 LQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLmnqlaelngsignycQDVTDAQIKNELLESEMKNLKKCVS 1935
Cdd:PRK03918   167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVL---------------REINEISSELPELREELEKLEKEVK 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1936 ELEEEKQ---QLVKEKTKVESEIRKEYlEKIQGAQKEPGNKshaKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2012
Cdd:PRK03918   232 ELEELKEeieELEKELESLEGSKRKLE-EKIRELEERIEEL---KKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLD 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2013 ALEFVQTESQKdLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLK--KELQSNKESVKSQMKQKD- 2089
Cdd:PRK03918   308 ELREIEKRLSR-LEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEeaKAKKEELERLKKRLTGLTp 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2090 EDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLN--KKDKEIQQVQENL---DSTVAQLAAFTKSMS 2164
Cdd:PRK03918   387 EKLEKELEELE----KAKEEIEEEISKITARIGELKKEIKELKKAIEelKKAKGKCPVCGRElteEHRKELLEEYTAELK 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2165 SLQDDRDRVIDEAKKWERKFsdaiqTKEEEIRLKEENCSVLKDQLRQMSIHMEELK-INISRLEhdkqiwesKAQTEVQL 2243
Cdd:PRK03918   463 RIEKELKEIEEKERKLRKEL-----RELEKVLKKESELIKLKELAEQLKELEEKLKkYNLEELE--------KKAEEYEK 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2244 QQKVCDTLQGENKELLSQLEETRHLyhnsQNELAKLESELNILKDQLTDLSNSLEKCK-EQKENLEGIIRQQEaDIQNSK 2322
Cdd:PRK03918   530 LKEKLIKLKGEIKSLKKELEKLEEL----KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELE-PFYNEY 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2323 FSYEQLETDLQASRELTSRLHEEINMKEqKMISLLSGKEEAIQVAIAELRQQHDKE----IKELENLLSQEEEENIVLEE 2398
Cdd:PRK03918   605 LELKDAEKELEREEKELKKLEEELDKAF-EELAETEKRLEELRKELEELEKKYSEEeyeeLREEYLELSRELAGLRAELE 683

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622909132 2399 ENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILE 2462
Cdd:PRK03918   684 ELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1274-1747 7.44e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.54  E-value: 7.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1274 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVfqlqDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGL 1353
Cdd:PRK03918   189 ENIEELIKEKEKELEEVLREINEISSELPELREEL----EKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIREL 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1354 E-HLRELQPELDELQKL------ISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQL 1426
Cdd:PRK03918   265 EeRIEELKKEIEELEEKvkelkeLKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK-ELEEKEERLEEL 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1427 QVELCEMKQKPEEIEEESRAKQQIQRKLqaaliSRKEALKENkslqeelsLARDTIEHLTKSLADVESHVSAQNKEKDRV 1506
Cdd:PRK03918   344 KKKLKELEKRLEELEERHELYEEAKAKK-----EELERLKKR--------LTGLTPEKLEKELEELEKAKEEIEEEISKI 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1507 LGRLALLQEErdklITEMDRSLLENQSLSGSCESLKlalEGLTEDKEKLVKEIESLKSSKIA-ESSEWQEKHKELQKEye 1585
Cdd:PRK03918   411 TARIGELKKE----IKELKKAIEELKKAKGKCPVCG---RELTEEHRKELLEEYTAELKRIEkELKEIEEKERKLRKE-- 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1586 ilLQSYENVSNEAERIQHVVEAVRQEKqELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEEN 1665
Cdd:PRK03918   482 --LRELEKVLKKESELIKLKELAEQLK-ELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKL 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1666 DRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEAT 1745
Cdd:PRK03918   559 AELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAET 638


                   ..
gi 1622909132 1746 EK 1747
Cdd:PRK03918   639 EK 640
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1284-1947 9.45e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 58.11  E-value: 9.45e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1284 ETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGL-EHLRELQPE 1362
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1363 LDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEhderIKQLQVELCEMKQKPEEIEE 1442
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQ----KEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1443 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLIT 1522
Cdd:TIGR04523  188 NIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1523 EMDRSLLEnqslsgsCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSewQEKHKELQKEYEILLQSYENVSNEAERIQ 1602
Cdd:TIGR04523  268 QLSEKQKE-------LEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWN--KELKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1603 HVVEAVRQEKQELYGKlrstEANKKETEKQLQEaekemeemkekmrkfaksKQQKILELEEENDRLraevhpaggtaKEC 1682
Cdd:TIGR04523  339 QLNEQISQLKKELTNS----ESENSEKQRELEE------------------KQNEIEKLKKENQSY-----------KQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1683 METLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLeaTEKHDNQMNVTEEATQSI 1762
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL--TNQDSVKELIIKNLDNTR 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1763 PGETEDQDSLSMSTRPAcsesvpsENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAL 1842
Cdd:TIGR04523  464 ESLETQLKVLSRSINKI-------KQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEK 536

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1843 LSQISTKDGELKLLQEEVSKMNL------LNQQIQEELSRVTKLKETAEEEKDDLEER------LMNQLAELNGSIGNYC 1910
Cdd:TIGR04523  537 ESKISDLEDELNKDDFELKKENLekeideKNKEIEELKQTQKSLKKKQEEKQELIDQKekekkdLIKEIEEKEKKISSLE 616

                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 1622909132 1911 QDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKE 1947
Cdd:TIGR04523  617 KELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1703-2462 1.39e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.77  E-value: 1.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1703 EYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQ--MNVTEEATQSIPGETEDQDSLSMSTRPAC 1780
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkiKDLGEEEQLRVKEKIGELEAEIASLERSI 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1781 SESVPSENSANPAVSEDVSshdEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEV 1860
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEA---EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1861 S----KMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSE 1936
Cdd:TIGR02169  388 KdyreKLEKLKREINELKRELDRLQEELQRLSEELAD-LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1937 LEEEKQQLVKEKTKVESEIRK---EYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK-ISALERT-- 2010
Cdd:TIGR02169  467 YEQELYDLKEEYDRVEKELSKlqrELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyATAIEVAag 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2011 --------------VKALEFVQTE---------------SQKDLEITKEN-----LAQAVEHRKKAQAelaSFKVLLDDT 2056
Cdd:TIGR02169  547 nrlnnvvveddavaKEAIELLKRRkagratflplnkmrdERRDLSILSEDgvigfAVDLVEFDPKYEP---AFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2057 qseaarVLADNLKLKKELQSNKESV--------KSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETI 2128
Cdd:TIGR02169  624 ------LVVEDIEAARRLMGKYRMVtlegelfeKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2129 GEIQvtlnkkdKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQ 2208
Cdd:TIGR02169  698 RRIE-------NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2209 lrQMSIHMEELKINisrlehdkQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKD 2288
Cdd:TIGR02169  771 --EEDLHKLEEALN--------DLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2289 QLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKM--ISLLSGKEEAIQV 2366
Cdd:TIGR02169  841 QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIeeLEAQIEKKRKRLS 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2367 AIAELRQQHDKEIKELENLLSQEEEENIVLEEENK--KAVDKTNQLMETLNAIKKENIQQ----KAQLDSFVKSMSSLQN 2440
Cdd:TIGR02169  921 ELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDvqAELQRVEEEIRALEPVNMLAIQEyeevLKRLDELKEKRAKLEE 1000

                          810       820
                   ....*....|....*....|..
gi 1622909132 2441 DRDRIVGDYQQLEERHLSVILE 2462
Cdd:TIGR02169 1001 ERKAILERIEEYEKKKREVFME 1022
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1272-1747 2.00e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.00  E-value: 2.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1272 SVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINkqglEIESLKTASHEAEVRAESLQQKLESSQLQIA 1351
Cdd:PRK03918   239 EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK----ELKELKEKAEEYIKLSEFYEEYLDELREIEK 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1352 GLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDlIKALHTQLE-MQAKEHDERIKQLQVEL 1430
Cdd:PRK03918   315 RLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEE-AKAKKEELErLKKRLTGLTPEKLEKEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1431 CEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTI--EHLTKSLADVESHVSAQNKEKDRVLG 1508
Cdd:PRK03918   394 EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELteEHRKELLEEYTAELKRIEKELKEIEE 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1509 RLALLQEERDKLITEM--DRSLLENQSLSGSCESLKLALEGLT-EDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYE 1585
Cdd:PRK03918   474 KERKLRKELRELEKVLkkESELIKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1586 IllqsyenvSNEAERIQHVVEAVRQEKQELYGKLRSTE-ANKKETEKQLQEAEKEMEE--MKEKMRKFAKSKQQKILELE 1662
Cdd:PRK03918   554 L--------KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPFYNEylELKDAEKELEREEKELKKLE 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1663 EENDRLRAEVHPAGGTAKECMETLLSSNAS--------MKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLES 1734
Cdd:PRK03918   626 EELDKAFEELAETEKRLEELRKELEELEKKyseeeyeeLREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705

                          490
                   ....*....|...
gi 1622909132 1735 NVSKQANLEATEK 1747
Cdd:PRK03918   706 REKAKKELEKLEK 718
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1271-1904 2.10e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.05  E-value: 2.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1271 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEvfQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQI 1350
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQD--RIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQA 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1351 AGLEHLRELQpeldelqklISEKEEDVSYLSGQLREKEAALtkiqteiieqEDLIKALHTQLEMQakehderikqlQVEL 1430
Cdd:pfam15921  309 RNQNSMYMRQ---------LSDLESTVSQLRSELREAKRMY----------EDKIEELEKQLVLA-----------NSEL 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1431 CEMKQKPEEIEEESRAKQQIQRKLQAALISRKEAL----KENKSLQEELSLARDTIEHLTKSLADveshvsaQNKEKDRV 1506
Cdd:pfam15921  359 TEARTERDQFSQESGNLDDQLQKLLADLHKREKELslekEQNKRLWDRDTGNSITIDHLRRELDD-------RNMEVQRL 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1507 LgrlALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIA-ESSE---------WQEK 1576
Cdd:pfam15921  432 E---ALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTlESSErtvsdltasLQEK 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1577 HK----------ELQKEYEILLQSYENVSNEAERIQH-----------------VVEAVRQEKQ---ELYGKLRSTEANK 1626
Cdd:pfam15921  509 ERaieatnaeitKLRSRVDLKLQELQHLKNEGDHLRNvqtecealklqmaekdkVIEILRQQIEnmtQLVGQHGRTAGAM 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1627 KETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEvhpaggtakecMETLLSSNASMKEEVERVKMEYET 1706
Cdd:pfam15921  589 QVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELE-----------KVKLVNAGSERLRAVKDIKQERDQ 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1707 LSKKFQSLMSEKDSLSEEVQDLKHQLESNVskqanlEATEKHDNQMNVTEEATQSipgETEDQDSLSMSTrpacsesvps 1786
Cdd:pfam15921  658 LLNEVKTSRNELNSLSEDYEVLKRNFRNKS------EEMETTTNKLKMQLKSAQS---ELEQTRNTLKSM---------- 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1787 ENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEE--------------EKQKNKEFSQTLENERNALLSQISTKDGE 1852
Cdd:pfam15921  719 EGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEamtnankekhflkeEKNKLSQELSTVATEKNKMAGELEVLRSQ 798

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622909132 1853 LKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNG 1904
Cdd:pfam15921  799 ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1916-2729 2.21e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.90  E-value: 2.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1916 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 1995
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1996 DCIRYQEKISALERTVKalefvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2075
Cdd:pfam02463  259 EIEKEEEKLAQVLKENK-------EEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2076 SNKESVKSQMKQKDEDLERRL------EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2149
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREaeeeeeEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2150 dstvaQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHD 2229
Cdd:pfam02463  412 -----ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2230 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILK--DQLTDLSNSLEKCKEQKENL 2307
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAisTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2308 EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS 2387
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2388 QEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLI 2467
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2468 QEAAAENNKLKEEIR----------GLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNK 2537
Cdd:pfam02463  727 VQEAQDKINEELKLLkqkideeeeeEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2538 YAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALL 2617
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2618 SSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKD 2697
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1622909132 2698 LTAQIQSFGRSMSSLQNSRDHANEELDELKRK 2729
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1356-1572 2.39e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 2.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1356 LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1435
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1436 KPEEIEEESRAKQQIQRKLQAALI----SRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLA 1511
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909132 1512 LLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSE 1572
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 912-1728 2.53e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.00  E-value: 2.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  912 EAKKEQVEEDNEVVsglKQNYDEMSpaglISKEELQHEFDLLKKENEQRKRKLqaALINRKELLQRVSRLEEELANLKDQ 991
Cdd:TIGR02169  169 DRKKEKALEELEEV---EENIERLD----LIIDEKRQQLERLRREREKAERYQ--ALLKEKREYEGYELLKEKEALERQK 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  992 SKKEIPLSESERgEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQ 1071
Cdd:TIGR02169  240 EAIERQLASLEE-ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1072 DKTNQIDLLQAEISENQVIIQklttsntdasdgdsvalvketvvisppgtdsgehwkpELEEKILALEKEKEQLQKKLQE 1151
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIE-------------------------------------ELEREIEEERKRRDKLTEEYAE 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1152 ALTSRKAILKKAQEKE---RHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREsIDGKLPSPDQQewcsp 1228
Cdd:TIGR02169  362 LKEELEDLRAELEEVDkefAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD-LNAAIAGIEAK----- 435

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1229 TPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQggTSVAQIKAQLKEIETEKEKLE--LKISSTTSELTKKSE 1306
Cdd:TIGR02169  436 INELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK--EEYDRVEKELSKLQRELAEAEaqARASEERVRGGRAVE 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1307 EVF------------QLQDQINKQGLEIES-----LKTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKL 1369
Cdd:TIGR02169  514 EVLkasiqgvhgtvaQLGSVGERYATAIEVaagnrLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSIL 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1370 ISEKEEDVSY----------------------------------------LSGQLREKEAALTKIQTEIIEQEDLIKALH 1409
Cdd:TIGR02169  594 SEDGVIGFAVdlvefdpkyepafkyvfgdtlvvedieaarrlmgkyrmvtLEGELFEKSGAMTGGSRAPRGGILFSRSEP 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1410 TQLEMQAkehdERIKQLQVELCEMKQKPEEIEEESRAKQQ----IQRKLQAALISRKEALKENKSLQEELSLARDTIEHL 1485
Cdd:TIGR02169  674 AELQRLR----ERLEGLKRELSSLQSELRRIENRLDELSQelsdASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1486 TKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLEN------------QSLSGSCESLKLALEGLTEDKE 1553
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelskleeevSRIEARLREIEQKLNRLTLEKE 829

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1554 KLVKEIESLKSSKIaessEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQL 1633
Cdd:TIGR02169  830 YLEKEIQELQEQRI----DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1634 QEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTA------------KECMETLLSSNASMKEEVERVK 1701
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELsledvqaelqrvEEEIRALEPVNMLAIQEYEEVL 985

                          890       900
                   ....*....|....*....|....*..
gi 1622909132 1702 MEYETLSKKFQSLMSEKDSLSEEVQDL 1728
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1402-2147 3.42e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.28  E-value: 3.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1402 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1478
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKfylRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1479 RDT-IEHLTKSLADVESHVSaqnkekdRVLGRLALLQEERDKLITEMDR-SLLENQSLSGSCESLKLALEgltedkeklv 1556
Cdd:pfam15921  168 SNTqIEQLRKMMLSHEGVLQ-------EIRSILVDFEEASGKKIYEHDSmSTMHFRSLGSAISKILRELD---------- 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1557 KEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYEnvsneaERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQea 1636
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLE-- 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1637 ekemeEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLms 1716
Cdd:pfam15921  303 -----IIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNL-- 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1717 eKDSLSEEVQDL-KHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVS 1795
Cdd:pfam15921  376 -DDQLQKLLADLhKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1796 EDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKM----NLLNQQIQ 1871
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLrsrvDLKLQELQ 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1872 EELSRVTKLKETAEE---------EKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQ 1942
Cdd:pfam15921  535 HLKNEGDHLRNVQTEcealklqmaEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKD 614

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1943 QLVKEKTKVESEIRKEYLEKIQ----GAQKEPGNKSHAKELQELLKE---KQQEVKQLQKDC----IRYQEKISALERTV 2011
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKlvnaGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTT 694

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2012 KALEFVQTESQKDLEITKENL-------AQAVEHRKKAQAELASFKVLLDDTQSEaarvladnLKLKKELQSNKESVKSQ 2084
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLksmegsdGHAMKVAMGMQKQITAKRGQIDALQSK--------IQFLEEAMTNANKEKHF 766

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622909132 2085 MKQKDEDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQE 2147
Cdd:pfam15921  767 LKEEKNKLSQELSTVA----TEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1266-1512 3.48e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 3.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1266 ALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLES 1345
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1346 SQLQIAglehlrELQPELDELQKLISE------KEEDVSYLSGQLREKEAA--------LTKIQTEIIEQEDLIKALHTQ 1411
Cdd:COG4942     88 LEKEIA------ELRAELEAQKEELAEllralyRLGRQPPLALLLSPEDFLdavrrlqyLKYLAPARREQAEELRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1412 LEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELslaRDTIEHLTKSLAD 1491
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL---EALIARLEAEAAA 238

                          250       260
                   ....*....|....*....|.
gi 1622909132 1492 VESHVSAQNKEKDRvlGRLAL 1512
Cdd:COG4942    239 AAERTPAAGFAALK--GKLPW 257
PTZ00121 PTZ00121
MAEBL; Provisional
 1274-1837 4.62e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.30  E-value: 4.62e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1274 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTAshEAEVRAESLQQKLESSQLQIAGL 1353
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE--EAKKKADAAKKKAEEKKKADEAK 1397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1354 EHLRELQPELDELQKLISEKE--EDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelc 1431
Cdd:PTZ00121  1398 KKAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD---- 1473

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1432 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQ----EELSLARDTIEHLTKSLADvESHVSAQNKEKDRVL 1507
Cdd:PTZ00121  1474 EAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEakkaEEAKKADEAKKAEEAKKAD-EAKKAEEKKKADELK 1552

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1508 GRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEIL 1587
Cdd:PTZ00121  1553 KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK 1632

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1588 LQSYENVSNEAERIQHvVEAVRQEKQElyGKLRSTEANKKETE-----KQLQEAEKEMEEMKEKMRKFA--KSKQQKILE 1660
Cdd:PTZ00121  1633 KKVEQLKKKEAEEKKK-AEELKKAEEE--NKIKAAEEAKKAEEdkkkaEEAKKAEEDEKKAAEALKKEAeeAKKAEELKK 1709

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1661 LEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEyETLSKKFQSLMSEKDSLSEEVQDLKHQLESNvskqa 1740
Cdd:PTZ00121  1710 KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE----- 1783

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1741 nlEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAG 1820
Cdd:PTZ00121  1784 --ELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENG 1861

                          570
                   ....*....|....*..
gi 1622909132 1821 leEEKQKNKEFSQTLEN 1837
Cdd:PTZ00121  1862 --EDGNKEADFNKEKDL 1876
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1037-1636 5.99e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 5.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1037 EKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvi 1116
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA--- 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1117 sppgtdsgehwkpELEEKILALEKEKEQLQKKLQEALTSRKAIlkkaQEKERHLREELKQQKDDYNRLQEQFDEQSKENE 1196
Cdd:COG1196    299 -------------RLEQDIARLEERRRELEERLEELEEELAEL----EEELEELEEELEELEEELEEAEEELEEAEAELA 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1197 NIGDQLRQLQIQVREsidgklpspDQQEWcsptpgleeplfkateqhhtqpvlesnlcpdwpsHSEDASALQGGTSVAQI 1276
Cdd:COG1196    362 EAEEALLEAEAELAE---------AEEEL----------------------------------EELAEELLEALRAAAEL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1277 KAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE-H 1355
Cdd:COG1196    399 AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEaA 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1356 LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEdLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1435
Cdd:COG1196    479 LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA-VAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1436 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRV-------LG 1508
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVaarleaaLR 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1509 RLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILL 1588
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1622909132 1589 QSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1636
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1321-1772 6.01e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 6.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1321 EIESLKTASHEAEVRAESLQQKLESSQLQiagLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEI-- 1398
Cdd:PRK02224   221 EIERYEEQREQARETRDEADEVLEEHEER---REELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERdd 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1399 -IEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ--------------KPEEIEEESRAKQQIQRKLQAALISRKE 1463
Cdd:PRK02224   298 lLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVaaqahneeaeslreDADDLEERAEELREEAAELESELEEARE 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1464 ALKENKS----LQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRL----ALLQEERDKLitEMDRSLLE----- 1530
Cdd:PRK02224   378 AVEDRREeieeLEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREaeleATLRTARERV--EEAEALLEagkcp 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1531 --NQSLSGSceSLKLALEGLTEDKEKLVKEIESLKS--SKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVE 1606
Cdd:PRK02224   456 ecGQPVEGS--PHVETIEEDRERVEELEAELEDLEEevEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1607 AVRQEKQELYGKLRSTEANKKETEKQLQEAekemEEMKEKMRKFAKSKQQKILELEEENDRLRAevhpaggtakecMETL 1686
Cdd:PRK02224   534 EKRERAEELRERAAELEAEAEEKREAAAEA----EEEAEEAREEVAELNSKLAELKERIESLER------------IRTL 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1687 LSSNASMKEEVERVKMEYETLSKKFQslmSEKDSLSEEvQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGET 1766
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELND---ERRERLAEK-RERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673


                   ....*.
gi 1622909132 1767 EDQDSL 1772
Cdd:PRK02224   674 EERDDL 679
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1549-2126 6.43e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.46  E-value: 6.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1549 TEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIqhvvEAVRQEKQELYGKLRSTEANKKE 1628
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI----EELEKELESLEGSKRKLEEKIRE 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1629 TEKQLQEAEKEMEEMKEKMR----------------KFAKSKQQKILELEEENDRLRAEVhpaggtakECMETLLSSNAS 1692
Cdd:PRK03918   264 LEERIEELKKEIEELEEKVKelkelkekaeeyiklsEFYEEYLDELREIEKRLSRLEEEI--------NGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1693 MKEEVERVKMEYETLSKKFQSLmSEKDSLSEEVQDLKHQLESNVSKQANL---EATEKHDNQMNVTEEATQSIPGETEDQ 1769
Cdd:PRK03918   336 KEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELERLKKRLTGLtpeKLEKELEELEKAKEEIEEEISKITARI 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1770 DSLS--MSTRPACSESVPSENSANPAVSEDVSSHDE---INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLS 1844
Cdd:PRK03918   415 GELKkeIKELKKAIEELKKAKGKCPVCGRELTEEHRkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1845 QISTKD--GELKLLQEEVSKMNLlnqqiqEELSRVTKLKETAEEEKDDLEERLMNQLAELNgsignycqdvtdaqiKNEL 1922
Cdd:PRK03918   495 LIKLKElaEQLKELEEKLKKYNL------EELEKKAEEYEKLKEKLIKLKGEIKSLKKELE---------------KLEE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1923 LESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIqgaqkepgnkshaKELQELLKEkQQEVKQLQKDCIRYQE 2002
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL-------------KELEPFYNE-YLELKDAEKELEREEK 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2003 KISALERTVKALEFVQTESQKDLEITKENLAQAveHRKKAQAELASFKVLLDDTQSEAARVLADnlklKKELQSNKESVK 2082
Cdd:PRK03918   620 ELKKLEEELDKAFEELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAE----LEELEKRREEIK 693

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1622909132 2083 SQMKQKDEDLERRLEQAEEKHLKEK--KNMQEKLDALRREKVHLEE 2126
Cdd:PRK03918   694 KTLEKLKEELEEREKAKKELEKLEKalERVEELREKVKKYKALLKE 739
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1348-1623 6.56e-07

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 55.32  E-value: 6.56e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1348 LQIAGLEhlRELQPELDELQKL----ISEKEEDVSYLsgQLREKEAALTKIQTEIIEQEDLIKALHT----QLEMQAKEH 1419
Cdd:PRK05771     9 VLIVTLK--SYKDEVLEALHELgvvhIEDLKEELSNE--RLRKLRSLLTKLSEALDKLRSYLPKLNPlreeKKKVSVKSL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1420 DERIKQLQVELcemkqkpEEIEEESRAKQQIQRKLQA---ALISRKEALKENKSLQEELSLARDT-----------IEHL 1485
Cdd:PRK05771    85 EELIKDVEEEL-------EKIEKEIKELEEEISELENeikELEQEIERLEPWGNFDLDLSLLLGFkyvsvfvgtvpEDKL 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1486 TKSLADVESHVS---AQNKEKDRVLgrLALLQEERDKLITEMDRSLLENQSLSGScESLKLALEGLTEDKEKLVKEIESL 1562
Cdd:PRK05771   158 EELKLESDVENVeyiSTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE-GTPSELIREIKEELEEIEKERESL 234

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909132 1563 KsSKIAESSEwqekhkelqKEYEILLQSYENVSNEAERiqhvveavrqekQELYGKLRSTE 1623
Cdd:PRK05771   235 L-EELKELAK---------KYLEELLALYEYLEIELER------------AEALSKFLKTD 273
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1133-1839 7.89e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 7.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1133 EKILALEKEKEQ-----LQKKLQEALTSRKAILKKAQEKERHLREelkqqkddynrLQEQFDEQSKENENIGDQLRQLQI 1207
Cdd:TIGR02169  211 ERYQALLKEKREyegyeLLKEKEALERQKEAIERQLASLEEELEK-----------LTEEISELEKRLEEIEQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1208 QVRESIDGklpspdqqEWCSPTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsEDASAlqggtSVAQIKAQLKEIETEK 1287
Cdd:TIGR02169  280 KIKDLGEE--------EQLRVKEKIGELEAEIASLERSIAEKEREL--------EDAEE-----RLAKLEAEIDKLLAEI 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1288 EKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQlqiaglEHLRELQPELDELQ 1367
Cdd:TIGR02169  339 EELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK------REINELKRELDRLQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1368 KLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQlqvELCEMKQKPEEIEEESRAK 1447
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE-QLAADLSKYEQ---ELYDLKEEYDRVEKELSKL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1448 QQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESH------------------------VSAQNKEK 1503
Cdd:TIGR02169  489 QRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaagnrlnnvvveddavaKEAIELLK 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1504 DRVLGRLALL------QEERDKLITEMD---------------------------------------------------- 1525
Cdd:TIGR02169  569 RRKAGRATFLplnkmrDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgdtlvvedieaarrlmgkyrmvtlegel 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1526 --------------RSLLENQ-SLSGSCESLKLALEGLTEDKEKLVKE---IESLKSSKIAESSEWQEKHKELQKEYEIL 1587
Cdd:TIGR02169  649 feksgamtggsrapRGGILFSrSEPAELQRLRERLEGLKRELSSLQSElrrIENRLDELSQELSDASRKIGEIEKEIEQL 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1588 LQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQL-QEAEKEMEEMKEKMRKFAKSKQQKILELEEEND 1666
Cdd:TIGR02169  729 EQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLhKLEEALNDLEARLSHSRIPEIQAELSKLEEEVS 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1667 RLRA----------EVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQS--------------LMSEKDSLS 1722
Cdd:TIGR02169  809 RIEArlreieqklnRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEleeeleeleaalrdLESRLGDLK 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1723 EEVQDLKHQLESNVSKQANLEAT----EKHDNQMNVTEEATQSIPGETEDQDSlSMSTRPACSESVPSENSANPAVSEDV 1798
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQiekkRKRLSELKAKLEALEEELSEIEDPKG-EDEEIPEEELSLEDVQAELQRVEEEI 967

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1622909132 1799 SSHDEINN--------YLQQIDQLKERIAGLEEEKQKNKEFSQTLENER 1839
Cdd:TIGR02169  968 RALEPVNMlaiqeyeeVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1397-1995 8.35e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.07  E-value: 8.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1397 EIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELS 1476
Cdd:PRK03918   183 KFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIR 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1477 LARDTIEHLTKSLADVEshvsaqnkEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLtedkEKLV 1556
Cdd:PRK03918   263 ELEERIEELKKEIEELE--------EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI----EERI 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1557 KEIESLKSskiaESSEWQEKHKELQKEYEILLQSYEnvsnEAERIQHVVEAVRQEKQELYGKlrsteaNKKETEKQLQEA 1636
Cdd:PRK03918   331 KELEEKEE----RLEELKKKLKELEKRLEELEERHE----LYEEAKAKKEELERLKKRLTGL------TPEKLEKELEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1637 EKEMEEMKEKMRKFakskQQKILELEEENDRLRAEVHPAGGTAKECMetlLSSNASMKEEVERVKMEYETLSKKFQSLMS 1716
Cdd:PRK03918   397 EKAKEEIEEEISKI----TARIGELKKEIKELKKAIEELKKAKGKCP---VCGRELTEEHRKELLEEYTAELKRIEKELK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1717 EKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSanpAVSE 1796
Cdd:PRK03918   470 EIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIK---SLKK 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1797 DVSSHDEINNYLQqidQLKERIAGLEEEKqknKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSR 1876
Cdd:PRK03918   547 ELEKLEELKKKLA---ELEKKLDELEEEL---AELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1877 VTKLKETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNelLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR 1956
Cdd:PRK03918   621 LKKLEEELDKAFEELAE-TEKRLEELRKELEELEKKYSEEEYEE--LREEYLELSRELAGLRAELEELEKRREEIKKTLE 697

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1622909132 1957 --KEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 1995
Cdd:PRK03918   698 klKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLK 738
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 515-1394 8.39e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.06  E-value: 8.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  515 DVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQgkrAEEGDHEVLdQKEMKQMEgegiapikmevfledtgqnfplm 594
Cdd:TIGR02168  228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQ---ELEEKLEEL-RLEVSELE----------------------- 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  595 pneesslpavEKEQASTEHQNRTSEEISlndagvELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQE 674
Cdd:TIGR02168  281 ----------EEIEELQKELYALANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  675 IYE---KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV-VTELRAQVRQLEmnlaeaERQRR 750
Cdd:TIGR02168  345 KLEelkEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNeIERLEARLERLE------DRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  751 FDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKV 830
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  831 EELSQAlsQKELEIAKMDQLLLEKKRDVetLQQTIEEkdqqvteisfsmtekmvqlnEEKFSLGVEIkTLKEQLN-LLSR 909
Cdd:TIGR02168  499 ENLEGF--SEGVKALLKNQSGLSGILGV--LSELISV--------------------DEGYEAAIEA-ALGGRLQaVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  910 AEEAKKEQVEEDNEVVSG------LKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINrkeLLQRVsRLEE 983
Cdd:TIGR02168  554 NLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSY---LLGGV-LVVD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  984 ELANLKDQSKKEIPLSE---------SERGEVEEDKENKEYSekcVTSKCQEIEIsLKQTISEKEVELEHIRKDLEEKMA 1054
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRivtldgdlvRPGGVITGGSAKTNSS---ILERRREIEE-LEEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1055 AEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVisppgtdsgEHWKPELEEK 1134
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL---------EERLEEAEEE 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1135 ILALEKEKEQLQ---KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRE 1211
Cdd:TIGR02168  777 LAEAEAEIEELEaqiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1212 SIdgklpspdqqewcsptpgleeplfkateqhhtqpvlesnlcpdwpshsedASALQGGTSVAQIKAQLKEIETEKEKLE 1291
Cdd:TIGR02168  857 LA--------------------------------------------------AEIEELEELIEELESELEALLNERASLE 886

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1292 LKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGlehlrELQPELDELQKLIS 1371
Cdd:TIGR02168  887 EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE-----EYSLTLEEAEALEN 961

                          890       900
                   ....*....|....*....|...
gi 1622909132 1372 EKEEDVSYLSGQLREKEAALTKI 1394
Cdd:TIGR02168  962 KIEDDEEEARRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 671-1198 8.88e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.15  E-value: 8.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  671 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQ 748
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  749 RRFDYESQTAHHNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 821
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  822 RVRHISSKVEELSQA--LSQKELEIAKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 897
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  898 KTLKEqlnlLSRAEEAKKEQVEEDNEVvsglKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 977
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  978 VSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEE 1057
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1058 QLQAlvKEMNQTLQDKTNQIDLLQAEISENQviiqklttsntdasdgdsvalvketvvisppgtdsgehwKPELEEKILA 1137
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909132 1138 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1198
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1852-2705 9.43e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.98  E-value: 9.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1852 ELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELN---GSIGNYCQDVTDAQIKNELLESEMK 1928
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYllyLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1929 NLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALE 2008
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2009 RTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQK 2088
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLEL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2089 DEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTvaqlaaftkSMSSLQD 2168
Cdd:pfam02463  414 ARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKET---------QLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2169 DRDRVIDEAKKWERKFSdaiQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVC 2248
Cdd:pfam02463  485 QLELLLSRQKLEERSQK---ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2249 DTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQL 2328
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2329 ETDLQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTN 2408
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2409 QLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIvGDYQQLEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHM 2488
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLK-KEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2489 DDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRD 2568
Cdd:pfam02463  801 EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2569 LSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDK 2648
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE 960

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 2649 LKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSF 2705
Cdd:pfam02463  961 RNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2553-2757 1.06e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 1.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2553 EDLQRSSNALQ--EEKRDLSKEIESLKVSVSQLTRQVTALQEEG-TLGIYHAQLKVK---------EEELQRLSALLSSS 2620
Cdd:COG4913    235 DDLERAHEALEdaREQIELLEPIRELAERYAAARERLAELEYLRaALRLWFAQRRLElleaeleelRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2621 QKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLmvtKENKDLTA 2700
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFA---ALRAEAAA 391

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 2701 QIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSE 2757
Cdd:COG4913    392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDA 448
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 888-1549 1.19e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.59  E-value: 1.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  888 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEfDLLKKENEQRKRKLQAA 967
Cdd:TIGR00618  187 AKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQK-REAQEEQLKKQQLLKQL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  968 LINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRK 1047
Cdd:TIGR00618  266 RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRR 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1048 DLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPPGTDSGEHW 1127
Cdd:TIGR00618  346 LLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQ 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1128 KPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDdynrlQEQFDEQSKENENIGDQLRQLQI 1207
Cdd:TIGR00618  426 LAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-----KEQIHLQETRKKAVVLARLLELQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1208 QVRESIDGKLPSPDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNlcpdwpshSEDASALQGGTSVAQIKAQLKEIETEK 1287
Cdd:TIGR00618  501 EEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE--------DVYHQLTSERKQRASLKEQMQEIQQSF 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1288 EKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAE----------SLQQKLESSQLQIAGLEHLR 1357
Cdd:TIGR00618  573 SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpeqdlqdvrlHLQQCSQELALKLTALHALQ 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1358 ELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDL--IKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1435
Cdd:TIGR00618  653 LTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLaqCQTLLRELETHIEEYDREFNEIENASSSLGS 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1436 kpeEIEEESRAKQQIQRKLQAaliSRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQE 1515
Cdd:TIGR00618  733 ---DLAAREDALNQSLKELMH---QARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1622909132 1516 E-RDKLITEMDRSLLENQSLSGSCESLKLALEGLT 1549
Cdd:TIGR00618  807 EiGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKS 841
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 245-849 1.53e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  245 DLLQQELTAAEQRNQILSQQLQQIEAEHNtlrntvETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQAG-- 322
Cdd:COG1196    223 KELEAELLLLKLRELEAELEELEAELEEL------EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLae 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  323 QAQAELESRYSALEQKH-KAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQLEDQLQQKSK 401
Cdd:COG1196    297 LARLEQDIARLEERRRElEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  402 EISQFLNRlpLQQHETASQtcfpdvynegTQAVTEENIASLQKRVVELENEKGALL--LSSIELEELKAENEKLSSQITL 479
Cdd:COG1196    377 AEEELEEL--AEELLEALR----------AAAELAAQLEELEEAEEALLERLERLEeeLEELEEALAELEEEEEEEEEAL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  480 LEAQNRIGEADREVSEISIVDDANKRSSSTEESGQDVLENTFSQKHKELSVLLLEMKEAQEEI----AFLKLQLQGKRAE 555
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLegvkAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  556 EGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDTGQNFPLMPNEESSLPAVEKEQASTEHQNRTSEEISLNDAGVELKSTKQ 635
Cdd:COG1196    525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  636 DCDKSLSAVPDIGQcHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNAdNNSSAFTALSEER 715
Cdd:COG1196    605 ASDLREADARYYVL-GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE-LLAALLEAEAELE 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  716 DQLLAQVKELSVVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQF 795
Cdd:COG1196    683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622909132  796 SEQSTLIRSLQSQLQN---------KESEVLEgaERVRHISSKVEELSQALSQKELEIAKMDQ 849
Cdd:COG1196    763 EELERELERLEREIEAlgpvnllaiEEYEELE--ERYDFLSEQREDLEEARETLEEAIEEIDR 823
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 958-1621 1.72e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  958 EQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKeiplsesergeveedkenkeysekcvtskcqeieisLKQTISE 1037
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEE------------------------------------LEAELAE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1038 KEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvis 1117
Cdd:COG1196    265 LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE---- 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1118 ppgtdsgehwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENEN 1197
Cdd:COG1196    341 ------------ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1198 IGDQLRQLQIQVRESIdgklpspdqqewcsptpgleeplfkateqhhtqpvlesnlcpdwpshSEDASALQGGTSVAQIK 1277
Cdd:COG1196    409 EEALLERLERLEEELE-----------------------------------------------ELEEALAELEEEEEEEE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1278 AQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKtASHEAEVRAESLQQKLESSQLQIAGLEHLR 1357
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA-ARLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1358 ELQPELDELQKLISEKEEDV-SYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1436
Cdd:COG1196    521 GLAGAVAVLIGVEAAYEAALeAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAA 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1437 PEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEE 1516
Cdd:COG1196    601 VDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1517 RDKLITEMDRSLLENQslsgscESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSN 1596
Cdd:COG1196    681 LEELAERLAEEELELE------EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754

                          650       660
                   ....*....|....*....|....*
gi 1622909132 1597 EAERIQhVVEAVRQEKQELYGKLRS 1621
Cdd:COG1196    755 ELPEPP-DLEELERELERLEREIEA 778
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1041-1601 2.53e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.53  E-value: 2.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1041 ELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTtsntdaSDGDSVALVKETVVISPPG 1120
Cdd:PRK03918   173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLE------KEVKELEELKEEIEELEKE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1121 TDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAI--LKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1198
Cdd:PRK03918   247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELkeLKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1199 GDQLRQLQIQVRESidgklpspdqQEWCSPTPGLEEPLFKATEQHHTQPVLESNLcpdwpSHSEDASALQGGTSVAQIKA 1278
Cdd:PRK03918   327 EERIKELEEKEERL----------EELKKKLKELEKRLEELEERHELYEEAKAKK-----EELERLKKRLTGLTPEKLEK 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1279 QLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINkqglEIESLK----------TASHEAEVRAESLQQKLESSQL 1348
Cdd:PRK03918   392 ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIE----ELKKAKgkcpvcgrelTEEHRKELLEEYTAELKRIEKE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1349 QIAGLEHLRELQPELDELQKLISEKEEDVSY--LSGQLREKEAALTKIQTEIIEQE----DLIKALHTQLEMQ---AKEH 1419
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKKESELIKLkeLAEQLKELEEKLKKYNLEELEKKaeeyEKLKEKLIKLKGEiksLKKE 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1420 DERIKQLQVELCEMKQKPEEIEEE-SRAKQQIQRKLQAALISRKEALKENKSLQE---ELSLARDTIEHLTKSLADVESH 1495
Cdd:PRK03918   548 LEKLEELKKKLAELEKKLDELEEElAELLKELEELGFESVEELEERLKELEPFYNeylELKDAEKELEREEKELKKLEEE 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1496 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSllENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSkIAESSEWQE 1575
Cdd:PRK03918   628 LDKAFEELAETEKRLEELRKELEELEKKYSEE--EYEELREEYLELSRELAGLRAELEELEKRREEIKKT-LEKLKEELE 704

                          570       580
                   ....*....|....*....|....*.
gi 1622909132 1576 KHKELQKEYEILLQSYENVSNEAERI 1601
Cdd:PRK03918   705 EREKAKKELEKLEKALERVEELREKV 730
PTZ00121 PTZ00121
MAEBL; Provisional
 1948-2654 2.95e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.61  E-value: 2.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1948 KTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKdcIRYQEKISALERTVKALEFVQTESQKDLE- 2026
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEE--ARKAEDARKAEEARKAEDAKRVEIARKAEd 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2027 ITKENLAQAVEHRKKAQAELASFKV--------LLDDTQSEAARvLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ 2098
Cdd:PTZ00121  1163 ARKAEEARKAEDAKKAEAARKAEEVrkaeelrkAEDARKAEAAR-KAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2099 AeeKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQD--DRDRVIDE 2176
Cdd:PTZ00121  1242 A--KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADE 1319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2177 AKK---WERKFSDAIQTKEEEIRLKEEnCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQG 2253
Cdd:PTZ00121  1320 AKKkaeEAKKKADAAKKKAEEAKKAAE-AAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKK 1398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2254 ENKELLSQLEETRHLYHNSQN-ELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEAdiqnSKFSYEQLETDL 2332
Cdd:PTZ00121  1399 KAEEDKKKADELKKAAAAKKKaDEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEA----KKKAEEAKKADE 1474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2333 QASRELTSRLHEEINMK---EQKMISLLSGKEEAIQVAiAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQ 2409
Cdd:PTZ00121  1475 AKKKAEEAKKADEAKKKaeeAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2410 LMETLNAIKKENIQQKaqldsfvKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMD 2489
Cdd:PTZ00121  1554 AEELKKAEEKKKAEEA-------KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELK 1626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2490 DLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQlqqnkELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDL 2569
Cdd:PTZ00121  1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA-----EEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA 1701

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2570 SKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKL 2649
Cdd:PTZ00121  1702 KKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI 1781


                   ....*
gi 1622909132 2650 KKELK 2654
Cdd:PTZ00121  1782 EEELD 1786
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1274-2511 3.07e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 53.52  E-value: 3.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1274 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQIN---KQGLEIES----LKTASHEAEVRAESLQQKLESS 1346
Cdd:TIGR01612  540 KEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIKdlfDKYLEIDDeiiyINKLKLELKEKIKNISDKNEYI 619

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1347 QLQIAGLEHLRELQPELDELQKLISEKeedvsyLSGQLREKEAALTKIQTEIIE-QEDLIKALHTQLEMQAKEHDERIKQ 1425
Cdd:TIGR01612  620 KKAIDLKKIIENNNAYIDELAKISPYQ------VPEHLKNKDKIYSTIKSELSKiYEDDIDALYNELSSIVKENAIDNTE 693

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1426 LQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKE------ALKENKSLQEELSLARD-TIEHLTKSLADVESHVSA 1498
Cdd:TIGR01612  694 DKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKnelldiIVEIKKHIHGEINKDLNkILEDFKNKEKELSNKIND 773

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1499 QNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKS------SKIAESSE 1572
Cdd:TIGR01612  774 YAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFmkddflNKVDKFIN 853

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1573 WQEKHKE-LQKEYEILLQSYENVSNEaeriqhvveaVRQEKQELY-GKLRSTEANKKETEKQLQEAEKEMEEMKEKMR-- 1648
Cdd:TIGR01612  854 FENNCKEkIDSEHEQFAELTNKIKAE----------ISDDKLNDYeKKFNDSKSLINEINKSIEEEYQNINTLKKVDEyi 923

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1649 KFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMetllSSNASMKEEVERVKMEYET-LSKKFQSL-MSEKDSLSEEVQ 1726
Cdd:TIGR01612  924 KICENTKESIEKFHNKQNILKEILNKNIDTIKESN----LIEKSYKDKFDNTLIDKINeLDKAFKDAsLNDYEAKNNELI 999

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1727 DLKHQLESNVSKqaNLEATEKHdnQMNVTEEATQSIPGETEDqdslsmstrpacsesvpsensANPAVSE-DVSSHDEIN 1805
Cdd:TIGR01612 1000 KYFNDLKANLGK--NKENMLYH--QFDEKEKATNDIEQKIED---------------------ANKNIPNiEIAIHTSIY 1054

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1806 NYLQQIDQL-KERIAGLEEEKQKNKEFSQTLENERNALLSQIS----TKDGELKlLQEEVSK----MNLLNQQIQEELSR 1876
Cdd:TIGR01612 1055 NIIDEIEKEiGKNIELLNKEILEEAEINITNFNEIKEKLKHYNfddfGKEENIK-YADEINKikddIKNLDQKIDHHIKA 1133

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1877 VTKLKETAEEEKDDLEERLmnqlaelngsigNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK------QQLVKEKTK 1950
Cdd:TIGR01612 1134 LEEIKKKSENYIDEIKAQI------------NDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKniydeiKKLLNEIAE 1201

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1951 VESEirKEYLEKIQGAqkepgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK-ISALERTVKALEFVQTESQKDLEITK 2029
Cdd:TIGR01612 1202 IEKD--KTSLEEVKGI-----NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAyIEDLDEIKEKSPEIENEMGIEMDIKA 1274

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2030 ENLAQAVEHRKKAQAELASFK--VLLDDTQSEAARVLADNLK------LKKELQSNkesvKSQMKQKDEDLERRLEQ-AE 2100
Cdd:TIGR01612 1275 EMETFNISHDDDKDHHIISKKhdENISDIREKSLKIIEDFSEesdindIKKELQKN----LLDAQKHNSDINLYLNEiAN 1350

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2101 EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDstvaqLAAFTKSMSSLQDDRDrvIDEAKKW 2180
Cdd:TIGR01612 1351 IYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDIN-----LEECKSKIESTLDDKD--IDECIKK 1423

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2181 ERKFSDAIQTKEEEI-----RLKEENCSVLK-----DQLRQMSIHMEELKINISRLEHDKQIWESKAQTEvqlQQKVCDT 2250
Cdd:TIGR01612 1424 IKELKNHILSEESNIdtyfkNADENNENVLLlfkniEMADNKSQHILKIKKDNATNDHDFNINELKEHID---KSKGCKD 1500

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2251 LQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEA------DIQNSKFS 2324
Cdd:TIGR01612 1501 EADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKseqkikEIKKEKFR 1580

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2325 YEQLETDLQASRELTSRLHEEINMKEQKMISllsgkeeaiqvaIAELRQQHDKEIKELENLLSQEEEENIVLEEEN-KKA 2403
Cdd:TIGR01612 1581 IEDDAAKNDKSNKAAIDIQLSLENFENKFLK------------ISDIKKKINDCLKETESIEKKISSFSIDSQDTElKEN 1648

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2404 VDKTNQLMETLNAIK--KENIQ-QKAQLDSFVKSMSSLQNDRDRIVGDYQqleerhlSVILEKdqlIQEAAAEN-NKLKE 2479
Cdd:TIGR01612 1649 GDNLNSLQEFLESLKdqKKNIEdKKKELDELDSEIEKIEIDVDQHKKNYE-------IGIIEK---IKEIAIANkEEIES 1718

                         1290      1300      1310
                   ....*....|....*....|....*....|..
gi 1622909132 2480 EIRGLRSHMDDLNSENAKLDAELIQYREDLNQ 2511
Cdd:TIGR01612 1719 IKELIEPTIENLISSFNTNDLEGIDPNEKLEE 1750
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2207-2824 3.13e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 3.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2207 DQLRQMSIHMEELKINISRLEHDKQIWES--KAQTEVQLQQKVCDTLQGENKELLSQLEETRHlyHNSQNELAKLESELN 2284
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLRAALRLWFAQRRLELLEAEL--EELRAELARLEAELE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2285 ILKDQLTDLSNSLEKCKEQKENLEGIIRQQ-EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMisllsgkeEA 2363
Cdd:COG4913    313 RLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEF--------AA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2364 IQVAIAELRQQHDKEIKELENLLSQEEEENivleeenKKAVDKTNQLMETLNAIKkeniQQKAQLDSFVKSM-----SSL 2438
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAAL-------RDLRRELRELEAEIASLE----RRKSNIPARLLALrdalaEAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2439 QNDRD--RIVGDYQQLEERH---------------LSVILEKDQLIQEAAA-ENNKLKEEIRGLRSHMDDLNSENAKLDA 2500
Cdd:COG4913    454 GLDEAelPFVGELIEVRPEEerwrgaiervlggfaLTLLVPPEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDP 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2501 EliqyreDLNQVISIKDSQQKQLLEAQLQQNKELknkyakleeklkeseeanedlqrssnalqeekrdlskeiesLKV-S 2579
Cdd:COG4913    534 D------SLAGKLDFKPHPFRAWLEAELGRRFDY-----------------------------------------VCVdS 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2580 VSQLTRQVTALQEEGTL-GIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKkVGEIEDKLKKELKHLH- 2657
Cdd:COG4913    567 PEELRRHPRAITRAGQVkGNGTRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAE-AEERLEALEAELDALQe 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2658 -HDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAqiqsfgrsmsslqnsrdhANEELDELKRKYDASLKE 2736
Cdd:COG4913    646 rREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA------------------LEEQLEELEAELEELEEE 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2737 LAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYLEKLNQQLlskDEQLLHLssQLEDSYNQV-QSFSKAMASLQNER 2815
Cdd:COG4913    708 LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL---EERFAAA--LGDAVERELrENLEERIDALRARL 782


                   ....*....
gi 1622909132 2816 DHLWNELEK 2824
Cdd:COG4913    783 NRAEEELER 791
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
643-1080 3.31e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 3.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  643 AVPDIGQCHQDELERLKSQILELE-LNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLlaq 721
Cdd:PRK02224   177 GVERVLSDQRGSLDQLKAQIEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREEL--- 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  722 vkelsvvTELRAQVRQLEMNLAEAERQRR-FDYESQTAHHNLLT--EQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQ 798
Cdd:PRK02224   254 -------ETLEAEIEDLRETIAETEREREeLAEEVRDLRERLEEleEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  799 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQV------ 872
Cdd:PRK02224   327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFgdapvd 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  873 ----TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK----EQVEEDNEVVSGLKQNYDEmspaglisKE 944
Cdd:PRK02224   407 lgnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVETIEEDRER--------VE 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  945 ELQHEFDLLKKENEQRKRKLQAAlINRKELLQRVSRLEEELANLKDqskkeipLSESERGEVEEDKENKEysekcvtskc 1024
Cdd:PRK02224   479 ELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEE-------LIAERRETIEEKRERAE---------- 540

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132 1025 qeieiSLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLL 1080
Cdd:PRK02224   541 -----ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL 591
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2458-2874 3.81e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 3.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2458 SVILEKD--QLIQEAAAENNKLKEEIRGLrshmDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleAQLQQNKELK 2535
Cdd:TIGR02169  137 NVVLQGDvtDFISMSPVERRKIIDEIAGV----AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQL--ERLRREREKA 210

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2536 NKYakleeklkeseeanedlqrssNALQEEKRD-----LSKEIESLKVSVSQLTRQVTALqeegtlgiyhaqlkvkEEEL 2610
Cdd:TIGR02169  211 ERY---------------------QALLKEKREyegyeLLKEKEALERQKEAIERQLASL----------------EEEL 253

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2611 QRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHhdagimrNETETAEERVAELARDLVEMEQKLLM 2690
Cdd:TIGR02169  254 EKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELE-------AEIASLERSIAEKERELEDAEERLAK 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2691 VTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTfsmDLPEEnsl 2770
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE---KLKRE--- 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2771 syLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKfrksEEGKQRSAAqpatslAEVQSLK 2850
Cdd:TIGR02169  401 --INELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK----QEWKLEQLA------ADLSKYE 468

                          410       420
                   ....*....|....*....|....
gi 1622909132 2851 KAMSSLQNDRDRLLKELKNLQQQY 2874
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQREL 492
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1279-1429 3.82e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 51.08  E-value: 3.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1279 QLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHLRE 1358
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE 90

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622909132 1359 ---LQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1429
Cdd:COG1579     91 yeaLQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1680-2309 3.88e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.81  E-value: 3.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1680 KECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSL-------SEEVQDLKHQLESNV-----SKQANLEATEK 1747
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMadirrreSQSQEDLRNQLQNTVheleaAKCLKEDMLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1748 HDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSShdEINNYLQQIDQ----LKERIAGLEE 1823
Cdd:pfam15921  168 SNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGS--AISKILRELDTeisyLKGRIFPVED 245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1824 EKQKNKEFSQT-----LENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELsrvtklkETAEEEKDDLEERLMNQ 1898
Cdd:pfam15921  246 QLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQL-------EIIQEQARNQNSMYMRQ 318

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1899 LAELNGSIGNYCQDVTDA----QIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKS 1974
Cdd:pfam15921  319 LSDLESTVSQLRSELREAkrmyEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKE 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1975 HAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALefvQTESQKDLEitkeNLAQAVEHRKKAQAELASFKVLLD 2054
Cdd:pfam15921  399 QNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAM---KSECQGQME----RQMAAIQGKNESLEKVSSLTAQLE 471

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2055 DTQsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLE--QAEEKHLKEKKNMQ-EKLDALRREKVHLEETIGE- 2130
Cdd:pfam15921  472 STK-EMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEatNAEITKLRSRVDLKlQELQHLKNEGDHLRNVQTEc 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2131 --IQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVideakkwERKFSDA-IQTKEEEIRLKEENCSVLKD 2207
Cdd:pfam15921  551 eaLKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQL-------EKEINDRrLELQEFKILKDKKDAKIREL 623

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2208 QLRQMSIHMEELKINISRLEHDKQIWESKaqtevQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILK 2287
Cdd:pfam15921  624 EARVSDLELEKVKLVNAGSERLRAVKDIK-----QERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLK 698

                          650       660
                   ....*....|....*....|..
gi 1622909132 2288 DQLTDLSNSLEKCKEQKENLEG 2309
Cdd:pfam15921  699 MQLKSAQSELEQTRNTLKSMEG 720
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2561-3159 4.30e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.75  E-value: 4.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2561 ALQEEKRDLSK-----EIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQ 2635
Cdd:TIGR02168  217 ELKAELRELELallvlRLEELREELEELQEELKEAEEE--LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2636 KEAAKKVGEIEdKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNS 2715
Cdd:TIGR02168  295 NEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2716 RDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSEttfsmdlpeenslsyLEKLNQQLLSKDEQLLhlSSQLE 2795
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDR---------------RERLQQEIEELLKKLE--EAELK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2796 DSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYL 2875
Cdd:TIGR02168  437 ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQS 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2876 QINQ------EITELRP---------LKAQLQEYQDKTKTFQIM-QEELRQENLSWQH--ELHQLRMEKSSWEIHERRMK 2937
Cdd:TIGR02168  517 GLSGilgvlsELISVDEgyeaaieaaLGGRLQAVVVENLNAAKKaIAFLKQNELGRVTflPLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2938 -EQYLMAISDKDQQVSHLQNLIRELRSSSS------QAQPLKVQYQRQASPET----SASPDGSQN----------LIYE 2996
Cdd:TIGR02168  597 iEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvddldNALELAKKLRPGYRIVTldgdLVRPGGVITggsaktnssiLERR 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2997 TEL--LRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAVS 3074
Cdd:TIGR02168  677 REIeeLEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 3075 KEKgpLNIDVAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERD----------------- 3137
Cdd:TIGR02168  757 TEL--EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlrerleslerria 834

                          650       660
                   ....*....|....*....|....*.
gi 1622909132 3138 ----QRVAAENALSLAEEQIRRLEHS 3159
Cdd:TIGR02168  835 aterRLEDLEEQIEELSEDIESLAAE 860
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 440-1214 4.80e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.75  E-value: 4.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  440 ASLQKRVVELENEKGAL--LLSSIELEELKAENEKLSSQITLLEAQNRIGEADREVSEISIvDDANKRSSSTEESgQDVL 517
Cdd:TIGR02168  209 AEKAERYKELKAELRELelALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL-EELRLEVSELEEE-IEEL 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  518 ENTFSQKHKELSVLLLEMKEAQEEIAFLK---LQLQGKRAEEGDHEVLDQKEMKQMEGEgiapikmevfLEDTGQNFPLM 594
Cdd:TIGR02168  287 QKELYALANEISRLEQQKQILRERLANLErqlEELEAQLEELESKLDELAEELAELEEK----------LEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  595 PNEESSLPAVEKEQASTEHQNRTsEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQ- 673
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEl 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  674 EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQRRFDY 753
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  754 ESQTAHHNLLTEQIH-----SLSIEA----KSKDVKIEVLQNELDDVQLQfsEQSTLIRSL--------QSQLQNKESEV 816
Cdd:TIGR02168  516 SGLSGILGVLSELISvdegyEAAIEAalggRLQAVVVENLNAAKKAIAFL--KQNELGRVTflpldsikGTEIQGNDREI 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  817 LEGAERVRHISSKVEELSQALSqkeleiaKMDQLLLEKKRDVETLQQTIEE------------KDQQVTEISFSMTEKMV 884
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFDPKLR-------KALSYLLGGVLVVDDLDNALELakklrpgyrivtLDGDLVRPGGVITGGSA 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  885 QLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEdnevVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKL 964
Cdd:TIGR02168  667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAE----LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  965 QAalinrkeLLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEiSLKQTISEKEVELEH 1044
Cdd:TIGR02168  743 EQ-------LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK-ALREALDELRAELTL 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1045 IRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISppGTDSG 1124
Cdd:TIGR02168  815 LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEE--ALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1125 EHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQ 1204
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972

                          810
                   ....*....|
gi 1622909132 1205 LQIQVRESID 1214
Cdd:TIGR02168  973 RLKRLENKIK 982
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2095-2738 5.55e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.37  E-value: 5.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2095 RLEQAEEKHLKEKKNMQEKLDALRRE---KVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRD 2171
Cdd:PRK03918   159 DYENAYKNLGEVIKEIKRRIERLEKFikrTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2172 RvIDEAKKWERKFSDAIQTKEEEIRLKEEncsvlkdQLRQMSIHMEELKINISRLEHDKQIWEskaqtevqlqqkvcdtl 2251
Cdd:PRK03918   239 E-IEELEKELESLEGSKRKLEEKIRELEE-------RIEELKKEIEELEEKVKELKELKEKAE----------------- 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2252 qgENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEAdIQNSKFSYEQLETD 2331
Cdd:PRK03918   294 --EYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE-LEERHELYEEAKAK 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2332 LQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENIVLeeenKKAVDKTNQLM 2411
Cdd:PRK03918   371 KEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITA----RIGELKKEIKELKKAIEEL----KKAKGKCPVCG 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2412 ETLNAIKKENIqqkaqLDSFVKSMSSLQNDRDRIVGDYQQLEERhlSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2491
Cdd:PRK03918   443 RELTEEHRKEL-----LEEYTAELKRIEKELKEIEEKERKLRKE--LRELEKVLKKESELIKLKELAEQLKELEEKLKKY 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2492 NSENAKLDAEliQYREDLNQVISIKDSQQKqlLEAQLQQNKELKNKYAKleeklkeseeanedLQRSSNALQEEKRDLSK 2571
Cdd:PRK03918   516 NLEELEKKAE--EYEKLKEKLIKLKGEIKS--LKKELEKLEELKKKLAE--------------LEKKLDELEEELAELLK 577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2572 EIESLKV-SVSQLTRQVTALQEegtlgIYHAQLKVK--EEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIED- 2647
Cdd:PRK03918   578 ELEELGFeSVEELEERLKELEP-----FYNEYLELKdaEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEEl 652

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2648 ----------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLlmvtKENKDLTAQIQSFGRSMSSLqnsrd 2717
Cdd:PRK03918   653 ekkyseeeyeELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERV----- 723

                          650       660
                   ....*....|....*....|.
gi 1622909132 2718 hanEELDELKRKYDASLKELA 2738
Cdd:PRK03918   724 ---EELREKVKKYKALLKERA 741
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2274-2894 5.62e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.33  E-value: 5.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2274 NELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLEtdlQASRELTSRLheeinMKEQKM 2353
Cdd:TIGR04523   26 NIANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILE---QQIKDLNDKL-----KKNKDK 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2354 ISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMET---LNAIKKENIQQKAQLDS 2430
Cdd:TIGR04523   98 INKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLnnkYNDLKKQKEELENELNL 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2431 FVKSMSSLQNDRDRIVGDYQQLEERhLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLN 2510
Cdd:TIGR04523  178 LEKEKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLN 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2511 QVISIKDSQQKQLLEAQL---QQNKELKNKYAKLEEKLKESEEAN-EDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQ 2586
Cdd:TIGR04523  257 QLKDEQNKIKKQLSEKQKeleQNNKKIKELEKQLNQLKSEISDLNnQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKI 336

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2587 VTALQEegtlgiyhaQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIED------KLKKELKHLHHDA 2660
Cdd:TIGR04523  337 ISQLNE---------QISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNlesqinDLESKIQNQEKLN 407

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2661 GIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQL 2740
Cdd:TIGR04523  408 QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQK 487

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2741 KEQQGLLNRERHALLSETTFSmdlpeENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQS------FSKAMASLQNE 2814
Cdd:TIGR04523  488 QKELKSKEKELKKLNEEKKEL-----EEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDelnkddFELKKENLEKE 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2815 RDHLWNELEKFR---KSEEGKQRSAAQPATSL-AEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQ 2890
Cdd:TIGR04523  563 IDEKNKEIEELKqtqKSLKKKQEEKQELIDQKeKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNK 642


                   ....
gi 1622909132 2891 LQEY 2894
Cdd:TIGR04523  643 LKQE 646
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1277-1743 5.67e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.33  E-value: 5.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1277 KAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHL 1356
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1357 -----------RELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQ 1425
Cdd:TIGR04523  203 lsnlkkkiqknKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1426 LQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENksLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDR 1505
Cdd:TIGR04523  283 IKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEE--IQNQISQNNKIISQLNEQISQLKKELTNSESENSE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1506 VLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLAL--------------EGLTEDKEKLVKEIESLKSSKIAESS 1571
Cdd:TIGR04523  361 KQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIqnqeklnqqkdeqiKKLQQEKELLEKEIERLKETIIKNNS 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1572 EWQE----------KHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEME 1641
Cdd:TIGR04523  441 EIKDltnqdsvkelIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1642 EMKEKMRKFAKSKQQKILELEEENDRLRAEvhpAGGTAKECMETLLSSNasmKEEVERVKMEYETLSKKFQSLMSEKDSL 1721
Cdd:TIGR04523  521 SLKEKIEKLESEKKEKESKISDLEDELNKD---DFELKKENLEKEIDEK---NKEIEELKQTQKSLKKKQEEKQELIDQK 594

                          490       500
                   ....*....|....*....|..
gi 1622909132 1722 SEEVQDLKHQLESNVSKQANLE 1743
Cdd:TIGR04523  595 EKEKKDLIKEIEEKEKKISSLE 616
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 313-1093 6.16e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.43  E-value: 6.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  313 HLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQL 392
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  393 -------EDQLQQKSKEISQFlnRLPLQQHETASQ---TCFPDVYNEGTQAVTEENIAS----------LQKRVVELENE 452
Cdd:pfam15921  155 eaakclkEDMLEDSNTQIEQL--RKMMLSHEGVLQeirSILVDFEEASGKKIYEHDSMStmhfrslgsaISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  453 ----KGALLLSSIELEELKAENEKlSSQITLLEAQNRIGEADREvSEISIVDDANKRSS--STEESGQDVLENTFSQKHK 526
Cdd:pfam15921  233 isylKGRIFPVEDQLEALKSESQN-KIELLLQQHQDRIEQLISE-HEVEITGLTEKASSarSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  527 ELSVLLLEMKEAQEEIAFLKLQL-QGKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDTGQNFPLMPNEESSLPAVE 605
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRSELrEAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKRE 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  606 KEQASTEHQNR------TSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQIlelelnfhkaqeiyeKN 679
Cdd:pfam15921  391 KELSLEKEQNKrlwdrdTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI---------------QG 455

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  680 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSvvTELRAQVRQLEMNLAEAERQR-RFDYESQTA 758
Cdd:pfam15921  456 KNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLT--ASLQEKERAIEATNAEITKLRsRVDLKLQEL 533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  759 HHnLLTEQIHslsieakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS 838
Cdd:pfam15921  534 QH-LKNEGDH------------LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIN 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  839 QKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKM---VQLNEEKFSLGVEIKTLKEQLNLLSraeeakk 915
Cdd:pfam15921  601 DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLS------- 673

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  916 eqveEDNEVvsgLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELAnlkdqskke 995
Cdd:pfam15921  674 ----EDYEV---LKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQIT--------- 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  996 iplseSERGEVEEDKENKEYSEKCVTSKCQEIEIsLKQTISEKEVELEHIRKDlEEKMAAE-EQLQALVKEMNQTLQDKT 1074
Cdd:pfam15921  738 -----AKRGQIDALQSKIQFLEEAMTNANKEKHF-LKEEKNKLSQELSTVATE-KNKMAGElEVLRSQERRLKEKVANME 810

                          810
                   ....*....|....*....
gi 1622909132 1075 NQIDLLQAEISENQVIIQK 1093
Cdd:pfam15921  811 VALDKASLQFAECQDIIQR 829
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1277-1481 6.31e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 6.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1277 KAQLKEIETEKEKLELKISsttsELTKKSEEVFQLQDQINKQGLEIESLKTAShEAEVRAESLQQKLESSQLQiagLEHL 1356
Cdd:COG4913    609 RAKLAALEAELAELEEELA----EAEERLEALEAELDALQERREALQRLAEYS-WDEIDVASAEREIAELEAE---LERL 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1357 RELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEmKQK 1436
Cdd:COG4913    681 DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE----AAEDLARLELRALLE-ERF 755

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1622909132 1437 PEEIEEESRakQQIQRKLQAaliSRKEALKENKSLQEELSLARDT 1481
Cdd:COG4913    756 AAALGDAVE--RELRENLEE---RIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1437-1679 6.46e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 6.46e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1437 PEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEE 1516
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1517 RDKLITEMDRsLLENQSLSGSCESLKLALEGltEDKEKLVKEIESLKSSkiaessewQEKHKELQKEYEILLQSYENVSN 1596
Cdd:COG4942     99 LEAQKEELAE-LLRALYRLGRQPPLALLLSP--EDFLDAVRRLQYLKYL--------APARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1597 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAG 1676
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247


                   ...
gi 1622909132 1677 GTA 1679
Cdd:COG4942    248 FAA 250
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1698-2313 8.20e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 8.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1698 ERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEAteKHDNQMNVTEEATQSIPGETEDQDSLSMSTR 1777
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEA--ELEELRLELEELELELEEAQAEEYELLAELA 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1778 PACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQ 1857
Cdd:COG1196    299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1858 EEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELngsignycQDVTDAQIKNELLESEMKNLKKCVSEL 1937
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL--------EELEEALAELEEEEEEEEEALEEAAEE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1938 EEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISA--LERTVKALE 2015
Cdd:COG1196    451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrgLAGAVAVLI 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2016 FVQTESQKDLEITKENLAQAVeHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKsqmkqkdEDLERR 2095
Cdd:COG1196    531 GVEAAYEAALEAALAAALQNI-VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA-------IGAAVD 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2096 LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2175
Cdd:COG1196    603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2176 EAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGEN 2255
Cdd:COG1196    683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909132 2256 KELLSQLEETRhlyhnsqNELAKLES-------ELNILKDQLTDLSNSLEKCKEQKENLEGIIRQ 2313
Cdd:COG1196    763 EELERELERLE-------REIEALGPvnllaieEYEELEERYDFLSEQREDLEEARETLEEAIEE 820
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 12-495 8.70e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 8.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132   12 QERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEEKKAADNKIKKLKLHAKAKLT---SLNKHIEEMKAQGGTVLLTEPQ 88
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEeleEAEAELAEAEEALLEAEAELAE 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132   89 SEEQLSKHDKSSTEEEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMKQQLQEKEELISTLQA 168
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  169 QLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQR------------------KL 230
Cdd:COG1196    457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLaglrglagavavligveaAY 536

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  231 EEHEESLVGRAQVVDLLQQELTAAEQRN-------------------QILSQQLQQIEAEHNTLRNTVETEREESKILLE 291
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEylkaakagratflpldkirARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  292 KMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQN 371
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  372 SKLLQDKDEQAVQSAQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQTcfPDVYNEGTQAVTEENIASLQKRVVELEN 451
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE--LLEEEALEELPEPPDLEELERELERLER 774

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622909132  452 EKGAL----LLSSIELEELKAENEKLSSQI-TLLEA----QNRIGEADREVSE 495
Cdd:COG1196    775 EIEALgpvnLLAIEEYEELEERYDFLSEQReDLEEAretlEEAIEEIDRETRE 827
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
954-1485 9.13e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 9.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  954 KKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDqskkEIPLSESERGEVEEDKEN-----KEYSEKCVTSKCQEIE 1028
Cdd:PRK02224   184 DQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDE----EIERYEEQREQARETRDEadevlEEHEERREELETLEAE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1029 IS-LKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTL-------QDKTNQIDLLQAEISENQviiQKLTTSNTD 1100
Cdd:PRK02224   260 IEdLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAglddadaEAVEARREELEDRDEELR---DRLEECRVA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1101 ASDGDSVAlvketvvisppgtDSGEHWKPELEEKILALEKEKEQLQKKLQ---EALTSRKAILKKAQEKERHLREELKQQ 1177
Cdd:PRK02224   337 AQAHNEEA-------------ESLREDADDLEERAEELREEAAELESELEearEAVEDRREEIEELEEEIEELRERFGDA 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1178 KDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESID-----------GKLPSPDQQEWCSP-TPGLEEPLFKATEqhht 1245
Cdd:PRK02224   404 PVDLGNAEDFLEELREERDELREREAELEATLRTARErveeaealleaGKCPECGQPVEGSPhVETIEEDRERVEE---- 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1246 qpvLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESL 1325
Cdd:PRK02224   480 ---LEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1326 KTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVsylsGQLREKEAALTKIQTEIIEQEDLI 1405
Cdd:PRK02224   557 REAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEI----ERLREKREALAELNDERRERLAEK 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1406 KALHTQLEmqAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHL 1485
Cdd:PRK02224   633 RERKRELE--AEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEAL 710
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
671-876 1.13e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.17  E-value: 1.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  671 KAQEIYEKNLDEKAKEISNLNQLIEEFKKNADnnssaFTALSEERDQLLAQVkelsvvTELRAQVRQLEMNLAEAERQRR 750
Cdd:COG3206    175 KALEFLEEQLPELRKELEEAEAALEEFRQKNG-----LVDLSEEAKLLLQQL------SELESQLAEARAELAEAEARLA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  751 FDYESQTAHHNLLTEQIHSLSIEAKSKdvKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRH----- 825
Cdd:COG3206    244 ALRAQLGSGPDALPELLQSPVIQQLRA--QLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILAsleae 321

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132  826 ---ISSKVEELSQALSQKELEIAKMDQL---LLEKKRDVETLQQTIEEKDQQVTEIS 876
Cdd:COG3206    322 leaLQAREASLQAQLAQLEARLAELPELeaeLRRLEREVEVARELYESLLQRLEEAR 378
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1545-2151 1.22e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.17  E-value: 1.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1545 LEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1624
Cdd:TIGR04523  129 LEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKK 208

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1625 nKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDrlraevhpaggTAKECMETLLSSNASMKEEVERVKMEY 1704
Cdd:TIGR04523  209 -KIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS-----------NTQTQLNQLKDEQNKIKKQLSEKQKEL 276

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1705 ETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMStrpacsesv 1784
Cdd:TIGR04523  277 EQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQL--------- 347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1785 psENSANPAVSEDVSSHDEINNYLQQIDQLKEriagleeEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMN 1864
Cdd:TIGR04523  348 --KKELTNSESENSEKQRELEEKQNEIEKLKK-------ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQ 418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1865 LLNQQIQEELSRVTKLKETAEEEKDDLEerlmNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcvseleeEKQQL 1944
Cdd:TIGR04523  419 QEKELLEKEIERLKETIIKNNSEIKDLT----NQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQ-------NLEQK 487

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1945 VKEKTKVESEIRKEYLEKIQGAQKepgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFvqtesqkd 2024
Cdd:TIGR04523  488 QKELKSKEKELKKLNEEKKELEEK-------VKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF-------- 552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2025 lEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLErRLEQAEEKHL 2104
Cdd:TIGR04523  553 -ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELE-KAKKENEKLS 630

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909132 2105 KEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2151
Cdd:TIGR04523  631 SIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2311-3070 1.28e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2311 IRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEqKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS--- 2387
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREYEGYELLKEKEALERQKEAIERQLAsle 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2388 QEEEENIVLEEENKKAVDKTNQLMETLNA-IKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsvilEKDQL 2466
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKkIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE-------DAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2467 IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNqvisikdsqqkqLLEAQLQQ----NKELKNKYAKLE 2542
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELE------------DLRAELEEvdkeFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2543 EKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYhaQLKVKEEELQRLSALLSSSQK 2622
Cdd:TIGR02169  392 EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAL--EIKKQEWKLEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2623 RITELEEELVCVQKEAAKKVGEIeDKLKKELKHLHHDAGIMRNETETAEER---VAELARDLVEMEQKLLmvtkenkdLT 2699
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQREL-AEAEAQARASEERVRGGRAVEEVLKASiqgVHGTVAQLGSVGERYA--------TA 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2700 AQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPE-----ENSLSY-- 2772
Cdd:TIGR02169  541 IEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEfdpkyEPAFKYvf 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2773 -----LEKL--------NQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQrsaaqp 2839
Cdd:TIGR02169  621 gdtlvVEDIeaarrlmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ------ 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2840 atslAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEIT----ELRPLKAQLQEYQDKTKTFQIMQEELRQENLSW 2915
Cdd:TIGR02169  695 ----SELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEklkeRLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2916 QHELHQLRMEKSSWEIHERRMKEQYLMAISDK-DQQVSHLQNLIRELRSSSSQAQPLKVQYQrqaspetsaspDGSQNLI 2994
Cdd:TIGR02169  771 EEDLHKLEEALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTLEKEYLE-----------KEIQELQ 839

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132 2995 YETELLRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQEL 3070
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1385-2879 1.45e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 51.21  E-value: 1.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1385 REKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIEEE----SRAKQQIQRKLQAaLIS 1460
Cdd:TIGR01612  540 KEIEAGLKESYELAKNWKKLIHEIKKELE----EENEDSIHLEKEIKDLFDKYLEIDDEiiyiNKLKLELKEKIKN-ISD 614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1461 RKEALKENKSLQEELSLARDTIEHLTK-SLADVESHVSAQNKEKDRVLGRLA-LLQEERDKLITEMDRSLLENQSLSgsc 1538
Cdd:TIGR01612  615 KNEYIKKAIDLKKIIENNNAYIDELAKiSPYQVPEHLKNKDKIYSTIKSELSkIYEDDIDALYNELSSIVKENAIDN--- 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1539 eslklaleglTEDKEKLvkeiESLKSSKIAESSEWQEKHKELQKEYeilLQSYENVSNEAERIqhVVEAVRQEKQELYGK 1618
Cdd:TIGR01612  692 ----------TEDKAKL----DDLKSKIDKEYDKIQNMETATVELH---LSNIENKKNELLDI--IVEIKKHIHGEINKD 752

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1619 LRSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskQQKILELEEE-NDRlraevhpaggtakecmetllSSNASMKEEv 1697
Cdd:TIGR01612  753 LNKILEDFKNKEKELSNKINDYAKEKDELNKY----KSKISEIKNHyNDQ--------------------INIDNIKDE- 807

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1698 eRVKMEYETLSKKFQSLMSEKDSLSE---EVQDLKHQLESNVSKQANLEAT--EKHDNQMNVTEEATQSIPGETEDQDSL 1772
Cdd:TIGR01612  808 -DAKQNYDKSKEYIKTISIKEDEIFKiinEMKFMKDDFLNKVDKFINFENNckEKIDSEHEQFAELTNKIKAEISDDKLN 886

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1773 SMSTRPACSESVPSE-NSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKE--------------------- 1830
Cdd:TIGR01612  887 DYEKKFNDSKSLINEiNKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEilnknidtikesnlieksykd 966

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1831 -FSQTLENERNAL--------LSQISTKDGEL----KLLQEEV--SKMNLLNQQIQEELSRVTKLketaEEEKDDLEERL 1895
Cdd:TIGR01612  967 kFDNTLIDKINELdkafkdasLNDYEAKNNELikyfNDLKANLgkNKENMLYHQFDEKEKATNDI----EQKIEDANKNI 1042

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1896 MNQLAELNGSIGNYCQDVTDAQIKN-ELLESE-MKNLKKCVSELEEEKQQL----VKEKTKVESEIRKEYLEKIQGAQKE 1969
Cdd:TIGR01612 1043 PNIEIAIHTSIYNIIDEIEKEIGKNiELLNKEiLEEAEINITNFNEIKEKLkhynFDDFGKEENIKYADEINKIKDDIKN 1122

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1970 PGNK--SHAKELQELLKEKQQEVKQLQKdciryqeKISALERTVKALefVQTESQKDLEITKENLAQAVEHRKKAQAELa 2047
Cdd:TIGR01612 1123 LDQKidHHIKALEEIKKKSENYIDEIKA-------QINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEI- 1192

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2048 sfKVLLddtqSEAARVLADNLKLKK----ELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREK 2121
Cdd:TIGR01612 1193 --KKLL----NEIAEIEKDKTSLEEvkgiNLSYGKNLGKLFLEKIDEEKKKseHMIKAMEAYIEDLDEIKEKSPEIENEM 1266

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2122 VHLEETIGEIQV--TLNKKDKEIQQVQENLDSTVAQLAafTKSMSSLQDD-RDRVIDEAKKWERKFSDAIQTKEEEIRLK 2198
Cdd:TIGR01612 1267 GIEMDIKAEMETfnISHDDDKDHHIISKKHDENISDIR--EKSLKIIEDFsEESDINDIKKELQKNLLDAQKHNSDINLY 1344

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2199 EENCSVLkdqlrqmsihmeelkINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyhNSQNELAK 2278
Cdd:TIGR01612 1345 LNEIANI---------------YNILKLNKIKKIID-------------------EVKEYTKEIEENNK---NIKDELDK 1387

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2279 LESELNILKDQLtdlsnSLEKCKEQKE------NLEGIIrQQEADIQNSKFSYE-QLETDLQASRELT---SRLHEEINM 2348
Cdd:TIGR01612 1388 SEKLIKKIKDDI-----NLEECKSKIEstlddkDIDECI-KKIKELKNHILSEEsNIDTYFKNADENNenvLLLFKNIEM 1461

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2349 KEQKMISLLSGKEEaiqvaiaELRQQHDKEIKELENLLSQEEEENIVLEEeNKKAVDKTNQLMETLNAIKKENIQQKAQL 2428
Cdd:TIGR01612 1462 ADNKSQHILKIKKD-------NATNDHDFNINELKEHIDKSKGCKDEADK-NAKAIEKNKELFEQYKKDVTELLNKYSAL 1533

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2429 dSFVKSMSSLQNDRDRIVGDYQQLE----------ERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKL 2498
Cdd:TIGR01612 1534 -AIKNKFAKTKKDSEIIIKEIKDAHkkfileaeksEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKI 1612

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2499 DAELIQYREDLNQVISIK--------DSQQKQLLEAQLQQN------KELKNKYAKLEEKLKESEEANEDLQRSSNALQE 2564
Cdd:TIGR01612 1613 SDIKKKINDCLKETESIEkkissfsiDSQDTELKENGDNLNslqeflESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQ 1692

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2565 EKRDLS---------------KEIESLKVSVSQLTRQVTA---------LQEEGTLGIYHAQLKVKEEELQRLSALLSS- 2619
Cdd:TIGR01612 1693 HKKNYEigiiekikeiaiankEEIESIKELIEPTIENLISsfntndlegIDPNEKLEEYNTEIGDIYEEFIELYNIIAGc 1772

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2620 ----SQKRIT--ELEEELVCVQKEAAKKVgEIEDKLKKELKHLhhdagimrnetetaeeRVAELARDLVEMEQKLLMV-- 2691
Cdd:TIGR01612 1773 letvSKEPITydEIKNTRINAQNEFLKII-EIEKKSKSYLDDI----------------EAKEFDRIINHFKKKLDHVnd 1835

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2692 --TKENKDLTAQIQSFGRSMSSLQNSRDHaNEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENS 2769
Cdd:TIGR01612 1836 kfTKEYSKINEGFDDISKSIENVKNSTDE-NLLFDILNKTKDAYAGIIGKKYYSYKDEAEKIFINISKLANSINIQIQNN 1914

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2770 --LSYLEKLNQQLLSkdeqllHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSA---------AQ 2838
Cdd:TIGR01612 1915 sgIDLFDNINIAILS------SLDSEKEDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQdtlniifenQQ 1988

                         1610      1620      1630      1640
                   ....*....|....*....|....*....|....*....|.
gi 1622909132 2839 PATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQ 2879
Cdd:TIGR01612 1989 LYEKIQASNELKDTLSDLKYKKEKILNDVKLLLHKFDELNK 2029
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1275-2122 1.55e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.20  E-value: 1.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1275 QIKAQLKEIETEKEKLELKiSSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLES----SQLQI 1350
Cdd:TIGR00606  225 QITSKEAQLESSREIVKSY-ENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1351 AGLEH-----LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTK-------IQTEIIEQEDLIKALHTQLEMQAKE 1418
Cdd:TIGR00606  304 NDLYHnhqrtVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRlqlqadrHQEHIRARDSLIQSLATRLELDGFE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1419 HDERIKQLQVELCEMKQkpEEIEEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLARDTIEHLTKSLADVESHVSA 1498
Cdd:TIGR00606  384 RGPFSERQIKNFHTLVI--ERQEDEAKTAAQLCADLQSKERLKQEQADE---IRDEKKGLGRTIELKKEILEKKQEELKF 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1499 QNKEKDRVLGrlallqeerdklitEMDRSLLENQSLSGSCESLKLALE-GLTEDKEKLVKEIESLKSSKIAESSEWQEKH 1577
Cdd:TIGR00606  459 VIKELQQLEG--------------SSDRILELDQELRKAERELSKAEKnSLTETLKKEVKSLQNEKADLDRKLRKLDQEM 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1578 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLrSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQk 1657
Cdd:TIGR00606  525 EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLL-GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELAS- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1658 ileLEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEV--ERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESN 1735
Cdd:TIGR00606  603 ---LEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESdlERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSC 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1736 VSKQANLEATEKHDNQM-NVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQL 1814
Cdd:TIGR00606  680 CPVCQRVFQTEAELQEFiSDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1815 KERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQE-ELSRVTKLKETAEEEKDDLEE 1893
Cdd:TIGR00606  760 IQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGsDLDRTVQQVNQEKQEKQHELD 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1894 RLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNK 1973
Cdd:TIGR00606  840 TVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLE 919

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1974 SHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKEN--------LAQAVEHRKKAQAE 2045
Cdd:TIGR00606  920 KDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETelntvnaqLEECEKHQEKINED 999

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2046 LASFKVLLdDTQSEAARVLADNLKLKK---ELQSNKESVKSQMKQKDEDLERRLEQAEEKhlkekknMQEKLDALRREKV 2122
Cdd:TIGR00606 1000 MRLMRQDI-DTQKIQERWLQDNLTLRKrenELKEVEEELKQHLKEMGQMQVLQMKQEHQK-------LEENIDLIKRNHV 1071
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1694-2342 1.94e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.50  E-value: 1.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1694 KEEVERVKMEYE-----------------------------TLSKKFQSLMSEKDSL-------SEEVQDLKHQLESNV- 1736
Cdd:pfam15921   73 KEHIERVLEEYShqvkdlqrrlnesnelhekqkfylrqsviDLQTKLQEMQMERDAMadirrreSQSQEDLRNQLQNTVh 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1737 ----SKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSShdEINNYLQQID 1812
Cdd:pfam15921  153 eleaAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGS--AISKILRELD 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1813 Q----LKERIAGLEEEKQKNKEFSQT-----LENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELsrvtklkET 1883
Cdd:pfam15921  231 TeisyLKGRIFPVEDQLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQL-------EI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1884 AEEEKDDLEERLMNQLAELNGSIGNYCQDVTDA----QIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1959
Cdd:pfam15921  304 IQEQARNQNSMYMRQLSDLESTVSQLRSELREAkrmyEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLL 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1960 -----------LEKIQGAQ---KEPGNKSHAKELQELLKEKQQEV-------KQLQKDCI-RYQEKISALERTVKALEFV 2017
Cdd:pfam15921  384 adlhkrekelsLEKEQNKRlwdRDTGNSITIDHLRRELDDRNMEVqrleallKAMKSECQgQMERQMAAIQGKNESLEKV 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2018 QTESQKdLEITKENLAQAVEHRKKAQAELASFKVLLDD--------------TQSEAARVLAD-NLKLK----------- 2071
Cdd:pfam15921  464 SSLTAQ-LESTKEMLRKVVEELTAKKMTLESSERTVSDltaslqekeraieaTNAEITKLRSRvDLKLQelqhlknegdh 542

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2072 -KELQSNKESVKSQMKQKDEDLErRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK----KDKEIQQVQ 2146
Cdd:pfam15921  543 lRNVQTECEALKLQMAEKDKVIE-ILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilKDKKDAKIR 621

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2147 EnLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHME--------E 2218
Cdd:pfam15921  622 E-LEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMEtttnklkmQ 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2219 LKINISRLEHDKQIWESKA-------------QTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNI 2285
Cdd:pfam15921  701 LKSAQSELEQTRNTLKSMEgsdghamkvamgmQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELST 780

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 2286 LKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRL 2342
Cdd:pfam15921  781 VATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRL 837
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1261-2014 1.94e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.74  E-value: 1.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1261 SEDASALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLK-----TASHEAEVR 1335
Cdd:pfam02463  216 KEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKklqeeELKLLAKEE 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1336 AESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQ 1415
Cdd:pfam02463  296 EELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEEL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1416 AKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESH 1495
Cdd:pfam02463  376 LAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEK 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1496 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQE 1575
Cdd:pfam02463  456 QELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLG 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1576 KHKELQKEYEILLQSYEN--VSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKS 1653
Cdd:pfam02463  536 VAVENYKVAISTAVIVEVsaTADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEA 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1654 KQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLE 1733
Cdd:pfam02463  616 DEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEIL 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1734 SNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQ 1813
Cdd:pfam02463  696 RRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKE 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1814 LKERIAGLEEEKQ--KNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDL 1891
Cdd:pfam02463  776 LAEEREKTEKLKVeeEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEE 855

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1892 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPG 1971
Cdd:pfam02463  856 LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE 935

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 1622909132 1972 NKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKAL 2014
Cdd:pfam02463  936 EPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLM 978
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1271-2192 1.98e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.56  E-value: 1.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1271 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLE-------IESLKTASHEAEVRAESLQQKL 1343
Cdd:pfam01576  103 QHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKErklleerISEFTSNLAEEEEKAKSLSKLK 182

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1344 ESSQLQIAGLE-HLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE- 1421
Cdd:pfam01576  183 NKHEAMISDLEeRLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNa 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1422 --RIKQLQVELCEMkQKPEEIEEESRAKQQIQRKlqaALISRKEALKenKSLQEELSLARDTIEHLTKSLADVESHVSAQ 1499
Cdd:pfam01576  263 lkKIRELEAQISEL-QEDLESERAARNKAEKQRR---DLGEELEALK--TELEDTLDTTAAQQELRSKREQEVTELKKAL 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1500 NKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEgltEDKEKLVKEIESLKSSKI----------AE 1569
Cdd:pfam01576  337 EEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALE---SENAELQAELRTLQQAKQdsehkrkkleGQ 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1570 SSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRK 1649
Cdd:pfam01576  414 LQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQ 493

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1650 FAKSKQQKILELEEEND-RLRAEVHPAGGTAK------------ECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMS 1716
Cdd:pfam01576  494 LEDERNSLQEQLEEEEEaKRNVERQLSTLQAQlsdmkkkleedaGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEK 573

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1717 EKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQ--------DSLSMSTRPACSES----- 1783
Cdd:pfam01576  574 TKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRaeaearekETRALSLARALEEAleake 653

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1784 -VPSENSANPAVSED-VSSHDEINNYL-----------QQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQIStKD 1850
Cdd:pfam01576  654 eLERTNKQLRAEMEDlVSSKDDVGKNVhelerskraleQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFE-RD 732

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1851 GELKLLQEEVSKMNLLNQ--QIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSigNYCQDVTDAQIKNelLESEMK 1928
Cdd:pfam01576  733 LQARDEQGEEKRRQLVKQvrELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAA--NKGREEAVKQLKK--LQAQMK 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1929 NLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALE 2008
Cdd:pfam01576  809 DLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLE 888

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2009 RTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQK 2088
Cdd:pfam01576  889 ARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSS 968

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2089 DEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeIQVTLNKKDKEiqQVQENLDSTVAQLAAFTKSMSSLQD 2168
Cdd:pfam01576  969 IAALEAKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVL--LQVEDERRHAD--QYKDQAEKGNSRMKQLKRQLEEAEE 1044

                          970       980
                   ....*....|....*....|....
gi 1622909132 2169 DRDRVIDEAKKWERKFSDAIQTKE 2192
Cdd:pfam01576 1045 EASRANAARRKLQRELDDATESNE 1068
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 8-258 2.02e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 2.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132    8 QEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEEKKAADNKIKKLKLHAKakltSLNKHIEEMKAQGGTVLLTEP 87
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA----RLEERRRELEERLEELEEELA 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132   88 QSEEQLSKHDKSSTEEEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMKQQLQEKEELISTLQ 167
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  168 AQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEEslvGRAQVVDLL 247
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL---LEAALAELL 483

                          250
                   ....*....|.
gi 1622909132  248 QQELTAAEQRN 258
Cdd:COG1196    484 EELAEAAARLL 494
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1320-1958 2.11e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.67  E-value: 2.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1320 LEIESLktasheaEVRAESLQQKLESSQLQIAGLEHLRE-LQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEI 1398
Cdd:PRK01156   159 LEINSL-------ERNYDKLKDVIDMLRAEISNIDYLEEkLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAM 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1399 IEQEDLIKALH---------TQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENK 1469
Cdd:PRK01156   232 DDYNNLKSALNelssledmkNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKK 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1470 SLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRvlgrlallQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLT 1549
Cdd:PRK01156   312 QILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSR--------YDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYS 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1550 EDKEKLVKEIESLKSSKIAESSewqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELygklrstEANKKET 1629
Cdd:PRK01156   384 KNIERMSAFISEILKIQEIDPD-------AIKKELNEINVKLQDISSKVSSLNQRIRALRENLDEL-------SRNMEML 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1630 EKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNasmKEEVERVKMEYETLSK 1709
Cdd:PRK01156   450 NGQSVCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLE---SEEINKSINEYNKIES 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1710 KFQSLMSEKDSLSE-EVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSEN 1788
Cdd:PRK01156   527 ARADLEDIKIKINElKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEI 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1789 SANpavSEDVSSHDEinNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQ 1868
Cdd:PRK01156   607 EIG---FPDDKSYID--KSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIED 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1869 QIQEELSRVTKLKeTAEEEKDDLEERLMNQLAELNGSIGNycqdvtdaqiKNELLESeMKNLKKCVSELEEEKQQLvkEK 1948
Cdd:PRK01156   682 NLKKSRKALDDAK-ANRARLESTIEILRTRINELSDRIND----------INETLES-MKKIKKAIGDLKRLREAF--DK 747

                          650
                   ....*....|
gi 1622909132 1949 TKVESEIRKE 1958
Cdd:PRK01156   748 SGVPAMIRKS 757
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1276-1671 2.13e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 2.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1276 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKtaSHEAEVRAESLQQKLESSQlqiaglEH 1355
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN--NQKEQDWNKELKSELKNQE------KK 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1356 LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQVELCEMKQ 1435
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNLESQINDLES 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1436 KPEEIEEESrakQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQE 1515
Cdd:TIGR04523  399 KIQNQEKLN---QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1516 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKEL-QKEYEILLQSYENV 1594
Cdd:TIGR04523  476 SINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIsDLEDELNKDDFELK 555

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 1595 SNEaeriqhvVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1671
Cdd:TIGR04523  556 KEN-------LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKE 625
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2079-2786 2.22e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.50  E-value: 2.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2079 ESVKSQMKQKDEDLERRLEQAEEKHLKEK--------------KNMQEKLDAL----RREKVHLEETIGEIQVTLNKKDK 2140
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEKQKfylrqsvidlqtklQEMQMERDAMadirRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2141 EIQQVQENLDSTVAQLAAFTKSMSS----LQDDRDRVIDEAKKWERKFSDAIQTKEEEIRlkeENCSVLKDQLRQMSIHM 2216
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLShegvLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---SLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2217 EELKINISRLEHDKQIWESKAQTEVQL----QQKVCDTLQGENKELLSQLEETRHlyhNSQNELAKLESELNILKDQLTD 2292
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNKIELllqqHQDRIEQLISEHEVEITGLTEKAS---SARSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2293 lSNSLEKCkeQKENLEGIIRQQEADIQNSKFSYEQLETDLQ-----ASRELTSRLHEEINMKE---------QKMISLLS 2358
Cdd:pfam15921  311 -QNSMYMR--QLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlANSELTEARTERDQFSQesgnlddqlQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2359 GKEEAIQ-----------------VAIAELRQQHDK---EIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIK 2418
Cdd:pfam15921  388 KREKELSlekeqnkrlwdrdtgnsITIDHLRRELDDrnmEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLT 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2419 KENIQQKAQLDSFVKSMSSLQ---NDRDRIVGDYQqleerhlSVILEKDQLIQEAAAENNKLK-------EEIRGLRSHM 2488
Cdd:pfam15921  468 AQLESTKEMLRKVVEELTAKKmtlESSERTVSDLT-------ASLQEKERAIEATNAEITKLRsrvdlklQELQHLKNEG 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2489 DDLNSENAKLDAELIQYREDlNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSnaLQEEKRD 2568
Cdd:pfam15921  541 DHLRNVQTECEALKLQMAEK-DKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFK--ILKDKKD 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2569 lsKEIESLKVSVSQLTRQVTALQEEGTLGIyHAQLKVKEEELQRLSALlSSSQKRITELEEELVCVQKEAAKKVGEIE-- 2646
Cdd:pfam15921  618 --AKIRELEARVSDLELEKVKLVNAGSERL-RAVKDIKQERDQLLNEV-KTSRNELNSLSEDYEVLKRNFRNKSEEMEtt 693

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2647 -DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDE 2725
Cdd:pfam15921  694 tNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNK 773

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622909132 2726 LKRKYDASLKELAQLKEQQGLLnRERHALLSETTFSMDLP-EENSLSYLEklNQQLLSKDEQ 2786
Cdd:pfam15921  774 LSQELSTVATEKNKMAGELEVL-RSQERRLKEKVANMEVAlDKASLQFAE--CQDIIQRQEQ 832
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 942-1744 2.31e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 2.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  942 SKEELQHEFDLLKKENEQRKRKLQAaliNRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVT 1021
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISE---LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKE 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1022 SKCQEIEISLKQTISE---KEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQI-------DLLQAEISENQVII 1091
Cdd:TIGR02169  315 RELEDAEERLAKLEAEidkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELeevdkefAETRDELKDYREKL 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1092 QKLTtSNTDASDGDSVALVKETVVISPPGTDSGEHWKpELEEKILALEKEKEQLQKKLQEA---LTSRKAILKKAQEKER 1168
Cdd:TIGR02169  395 EKLK-REINELKRELDRLQEELQRLSEELADLNAAIA-GIEAKINELEEEKEDKALEIKKQewkLEQLAADLSKYEQELY 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1169 HLREELKQQKDDYNRLQEQFDEQSKenenigdqlrQLQIQVRESIDGKLPSPDQQEWCSPTPGLEEPLFKATEQHhtQPV 1248
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAEA----------QARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERY--ATA 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1249 LES-------NLCPDWPSHSEDASAL----QGGTS----VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQlqd 1313
Cdd:TIGR02169  541 IEVaagnrlnNVVVEDDAVAKEAIELlkrrKAGRAtflpLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFK--- 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1314 QINKQGLEIESLKTA-SHEAEVRAESLQQKL-ESSQLQIAGleHLRELQPELDELQKlisekEEDVSYLSGQLREKEAAL 1391
Cdd:TIGR02169  618 YVFGDTLVVEDIEAArRLMGKYRMVTLEGELfEKSGAMTGG--SRAPRGGILFSRSE-----PAELQRLRERLEGLKREL 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1392 TKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALisrkealKENKSL 1471
Cdd:TIGR02169  691 SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK-------SELKEL 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1472 QEELSLARDTIEHLTKSLADVESHvsaqnkekdrvlgrlaLLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTED 1551
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALNDLEAR----------------LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1552 KEKLVKEIESLKSSKIaessEWQEKHKELQKEyeillqsyenvsneaeriqhvVEAVRQEKQELYGKLRSTEANKKETEK 1631
Cdd:TIGR02169  828 KEYLEKEIQELQEQRI----DLKEQIKSIEKE---------------------IENLNGKKEELEEELEELEAALRDLES 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1632 QLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLrAEVHPAGGTAKECMETLLSSNASMKEEVERVkMEYETLSKKF 1711
Cdd:TIGR02169  883 RLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL-SELKAKLEALEEELSEIEDPKGEDEEIPEEE-LSLEDVQAEL 960

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1622909132 1712 QSLMSEKDSLS-------EEVQDLKHQLESNVSKQANLEA 1744
Cdd:TIGR02169  961 QRVEEEIRALEpvnmlaiQEYEEVLKRLDELKEKRAKLEE 1000
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1539-2132 2.58e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.32  E-value: 2.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1539 ESLKLALEGLTEDKEKLVKEIESLKsskiAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGK 1618
Cdd:COG1196    228 ELLLLKLRELEAELEELEAELEELE----AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQD 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1619 LRSTEANKKETEKQLQEAekemeemkekmrkfakskQQKILELEEENDRLRAEvhpaggtakecMETLLSSNASMKEEVE 1698
Cdd:COG1196    304 IARLEERRRELEERLEEL------------------EEELAELEEELEELEEE-----------LEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1699 RVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIpgETEDQDSLSMSTRP 1778
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER--LEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1779 ACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELK--LL 1856
Cdd:COG1196    433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvKA 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1857 QEEVSKMNLLNQQIQEELSRVtklketaEEEKDDLEERLMNQLAELNgsignycqdVTDAQIKNELLESEMKNLKKCVSE 1936
Cdd:COG1196    513 ALLLAGLRGLAGAVAVLIGVE-------AAYEAALEAALAAALQNIV---------VEDDEVAAAAIEYLKAAKAGRATF 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1937 LEEEKQQlvKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEF 2016
Cdd:COG1196    577 LPLDKIR--ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2017 VQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRL 2096
Cdd:COG1196    655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1622909132 2097 EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQ 2132
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2551-2757 2.62e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2551 ANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEE 2630
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR--IAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2631 LVCVQKEAAKKVGEI-----EDKLK-----KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTA 2700
Cdd:COG4942     99 LEAQKEELAELLRALyrlgrQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 2701 QIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSE 2757
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1273-1741 3.19e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.77  E-value: 3.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1273 VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAG 1352
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1353 LEHLRELQPELDELQKLISEKEEdvsylsgqLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAK----EHDERIKQLQV 1428
Cdd:COG4717    128 LPLYQELEALEAELAELPERLEE--------LEERLEELRELEEELEELEAELAELQEELEELLEqlslATEEELQDLAE 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1429 ELCEMKQKPEEIEEESRAKQQIQRKLQAA---LISRKEALKENKSLQEELSLAR----------------DTIEHLTKSL 1489
Cdd:COG4717    200 ELEELQQRLAELEEELEEAQEELEELEEEleqLENELEAAALEERLKEARLLLLiaaallallglggsllSLILTIAGVL 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1490 ADVESHVSAQNKEKDRvlgRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAE 1569
Cdd:COG4717    280 FLVLGLLALLFLLLAR---EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREA 356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1570 SSEWQE-KHKELQKEYEILLQSYeNVSNEAERIQHVVEAvrQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMR 1648
Cdd:COG4717    357 EELEEElQLEELEQEIAALLAEA-GVEDEEELRAALEQA--EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE 433

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1649 kfAKSKQQKILELEEENDRLRAEVhpagGTAKECMETLLSSN--ASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQ 1726
Cdd:COG4717    434 --LEELEEELEELEEELEELREEL----AELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLEEARE 507

                          490
                   ....*....|....*
gi 1622909132 1727 DLKHQLESNVSKQAN 1741
Cdd:COG4717    508 EYREERLPPVLERAS 522
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1133-1362 3.31e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 3.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1133 EKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1212
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAEL----EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE- 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1213 IDGKLpspDQQEwcsptpGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTS------VAQIKAQLKEIETE 1286
Cdd:COG4942     95 LRAEL---EAQK------EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAparreqAEELRADLAELAAL 165

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132 1287 KEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPE 1362
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1276-1887 3.36e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.63  E-value: 3.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1276 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAEslqqklessqlqiagleh 1355
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKE------------------ 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1356 lrELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALhTQLEMQAKEHDERIKQLQVELCEMKQ 1435
Cdd:TIGR04523  170 --ELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQI-SELKKQNNQLKDNIEKKQQEINEKTT 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1436 KPEEIEEesrakqqiqrKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQ- 1514
Cdd:TIGR04523  247 EISNTQT----------QLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSEl 316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1515 EERDKLITEMDRSLLENQSlsgsceslklALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQ---KEYEILLQSY 1591
Cdd:TIGR04523  317 KNQEKKLEEIQNQISQNNK----------IISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEklkKENQSYKQEI 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1592 ENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1671
Cdd:TIGR04523  387 KNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESL 466

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1672 vhpaggtaKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQ 1751
Cdd:TIGR04523  467 --------ETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKES 538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1752 MNVTEEATQSIPGETEDQDSLSmstrpacsesvpsensanpavsedvsshDEINNYLQQIDQLKERIAGLEEEKQKNKEF 1831
Cdd:TIGR04523  539 KISDLEDELNKDDFELKKENLE----------------------------KEIDEKNKEIEELKQTQKSLKKKQEEKQEL 590

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132 1832 SQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEE 1887
Cdd:TIGR04523  591 IDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQE 646
PTZ00121 PTZ00121
MAEBL; Provisional
 909-1579 4.37e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 4.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  909 RAEEAKKEQVEEDNEVVSGLK--QNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELA 986
Cdd:PTZ00121  1183 KAEEVRKAEELRKAEDARKAEaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARM 1262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  987 NLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEE-QLQALVKE 1065
Cdd:PTZ00121  1263 AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAaKKKAEEAK 1342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1066 MNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNtDASDGDSVALVKETVVISPPGTDSGEHWKPELEE--KILALEKEKE 1143
Cdd:PTZ00121  1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE-AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElkKAAAAKKKAD 1421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1144 QLQKKLQEAltsRKAILKKAQEKERHLREELKQQKDDYNRLQEQfdEQSKENENIGDQLRQLQIQVRESIDGKLPSPDQQ 1223
Cdd:PTZ00121  1422 EAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEA--KKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK 1496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1224 EWCSPTPGLEEPLFKATEQHHTQPvlesnlcpdwpshsedasalqggtsvAQIKAQLKEIETEKEKLELKisstTSELTK 1303
Cdd:PTZ00121  1497 KKADEAKKAAEAKKKADEAKKAEE--------------------------AKKADEAKKAEEAKKADEAK----KAEEKK 1546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1304 KSEEVFQLQDQinKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQ 1383
Cdd:PTZ00121  1547 KADELKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE 1624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1384 LREKEAALTKI-QTEIIEQEDLIKAlhTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRK 1462
Cdd:PTZ00121  1625 LKKAEEEKKKVeQLKKKEAEEKKKA--EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1463 EALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVlgrLALLQEERDKLITEMDRSLLENQSLSGSCESLK 1542
Cdd:PTZ00121  1703 KAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA---EEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA 1779

                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 1622909132 1543 LALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKE 1579
Cdd:PTZ00121  1780 VIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1264-1672 5.23e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 5.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1264 ASALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLE-IESLKTASHEAEVRAESLQQK 1342
Cdd:COG4913    281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDrLEQLEREIERLERELEERERR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1343 LESSQLQIAGLEH-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE 1421
Cdd:COG4913    361 RARLEALLAALGLpLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPA 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1422 RIKQLQVELCE---------------MKQKPEE------IE-------------------------------------EE 1443
Cdd:COG4913    441 RLLALRDALAEalgldeaelpfvgelIEVRPEEerwrgaIErvlggfaltllvppehyaaalrwvnrlhlrgrlvyerVR 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1444 SRAKQQIQRKLQAALISRKEALKENKS---LQEELSLARD-----------------TIEHLTKSLADVESHVSAQNKEK 1503
Cdd:COG4913    521 TGLPDPERPRLDPDSLAGKLDFKPHPFrawLEAELGRRFDyvcvdspeelrrhpraiTRAGQVKGNGTRHEKDDRRRIRS 600

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1504 DRVLG-----RLALLQEERDKL---ITEMDRSLLENQSLSGSCESLKLALEGLTE------DKEKLVKEIESLKS--SKI 1567
Cdd:COG4913    601 RYVLGfdnraKLAALEAELAELeeeLAEAEERLEALEAELDALQERREALQRLAEyswdeiDVASAEREIAELEAelERL 680

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1568 AESSEW----QEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEM 1643
Cdd:COG4913    681 DASSDDlaalEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG 760

                          490       500
                   ....*....|....*....|....*....
gi 1622909132 1644 KEKMRKFAKSKQQKILELEEENDRLRAEV 1672
Cdd:COG4913    761 DAVERELRENLEERIDALRARLNRAEEEL 789
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 8-496 8.49e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.39  E-value: 8.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132    8 QEDVQERLAYAEQLVVELKDIiRQKDVQLQQKDEALQEEKKAADNKIKKLKLHAKAKLTSLNKHIEEMKAQggtvlltep 87
Cdd:COG1196    308 EERRRELEERLEELEEELAEL-EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA--------- 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132   88 qsEEQLSKHDKSSTEEEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMKQQLQEKEELISTLQ 167
Cdd:COG1196    378 --EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  168 AQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGR-AQVVDL 246
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVlIGVEAA 535

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  247 LQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQA 326
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARY 615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  327 ELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQLEDQLQQKSKEISQF 406
Cdd:COG1196    616 YVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELEL 695

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  407 LNRLPLQQHETASQTcfpdvyNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRI 486
Cdd:COG1196    696 EEALLAEEEEERELA------EAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769

                          490
                   ....*....|
gi 1622909132  487 GEADREVSEI 496
Cdd:COG1196    770 ERLEREIEAL 779
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2186-2950 9.50e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.50  E-value: 9.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2186 DAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEET 2265
Cdd:TIGR00606  224 DQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2266 RHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEgiIRQQEADIQNSKFSYEQLETDLQAsreLTSRLHEE 2345
Cdd:TIGR00606  304 NDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELL--VEQGRLQLQADRHQEHIRARDSLI---QSLATRLE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2346 INMKEQKMISllsgkEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQK 2425
Cdd:TIGR00606  379 LDGFERGPFS-----ERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2426 AQLDSFVKSMSSLQNDRDRIVGDYQQL--EERHLSvILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE-- 2501
Cdd:TIGR00606  454 EELKFVIKELQQLEGSSDRILELDQELrkAERELS-KAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtt 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2502 -------LIQYREDLNQVISIKDSQQKQLLEAQL---QQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSK 2571
Cdd:TIGR00606  533 trtqmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINN 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2572 EIESLKVSVSQLTRQV----TALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKeAAKKVGEIED 2647
Cdd:TIGR00606  613 ELESKEEQLSSYEDKLfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCP-VCQRVFQTEA 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2648 KLKKELKHLHHDAGIMRNETETAEERVAELARD------LVEMEQKLL-MVTKENKDLTAQIQSFGRSMSSLQNSRDHAN 2720
Cdd:TIGR00606  692 ELQEFISDLQSKLRLAPDKLKSTESELKKKEKRrdemlgLAPGRQSIIdLKEKEIPELRNKLQKVNRDIQRLKNDIEEQE 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2721 EELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQ 2800
Cdd:TIGR00606  772 TLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKL 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2801 VQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ-INQ 2879
Cdd:TIGR00606  852 IQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEElISS 931

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909132 2880 EITELRPLKAQLQEYQDKTKT--------FQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQ 2950
Cdd:TIGR00606  932 KETSNKKAQDKVNDIKEKVKNihgymkdiENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ 1010
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 165-925 1.02e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.14  E-value: 1.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  165 TLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLhEDELLQLVTQADVETEMQQklRVLQRKLEEHEESLVGRAQVV 244
Cdd:TIGR02169  234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEI-EQLLEELNKKIKDLGEEEQ--LRVKEKIGELEAEIASLERSI 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  245 DLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQE--------------- 309
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEvdkefaetrdelkdy 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  310 ----------------EMRHLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSK 373
Cdd:TIGR02169  391 rekleklkreinelkrELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  374 LLQDKdeqavqsaQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQTCFPDVYNEGTQAV---TEENIASLQKRVVELE 450
Cdd:TIGR02169  471 LYDLK--------EEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIE 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  451 NEKGALLLSSIELEELKAE------NEKLSSQITLLEAqNRIGEADREVSEISivddankrssstEESGQDVLEN--TFS 522
Cdd:TIGR02169  543 VAAGNRLNNVVVEDDAVAKeaiellKRRKAGRATFLPL-NKMRDERRDLSILS------------EDGVIGFAVDlvEFD 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  523 QKHKELSVLLLEMKEAQEEIaflklqlqgkraeEGDHEVLDQKEMKQMEGEGIAP---IKMEVFLEDTGQNFPLMPNEES 599
Cdd:TIGR02169  610 PKYEPAFKYVFGDTLVVEDI-------------EAARRLMGKYRMVTLEGELFEKsgaMTGGSRAPRGGILFSRSEPAEL 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  600 SLPAVEKEQASTEHQNRTSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKN 679
Cdd:TIGR02169  677 QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  680 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKElsvvtELRAQVRQLEMNLAEAERQRrfdyesqtah 759
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS-----KLEEEVSRIEARLREIEQKL---------- 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  760 hNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQ 839
Cdd:TIGR02169  822 -NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE 900

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  840 KELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEkMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVE 919
Cdd:TIGR02169  901 LERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE-DEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQ 979


                   ....*.
gi 1622909132  920 EDNEVV 925
Cdd:TIGR02169  980 EYEEVL 985
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1798-2013 1.02e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1798 VSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEvskMNLLNQQIQEELSRV 1877
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE---LAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1878 TKLKETAEEEKDDLEERL------------------------------MNQLAE-LNGSIGNYCQDVTDAQIKNELLESE 1926
Cdd:COG4942     93 AELRAELEAQKEELAELLralyrlgrqpplalllspedfldavrrlqyLKYLAPaRREQAEELRADLAELAALRAELEAE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1927 MKNLKKCVSELEEEKQQLVKEKTKVESEIrkeylekiqgaqkepgnkshaKELQELLKEKQQEVKQLQKDCIRYQEKISA 2006
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLL---------------------ARLEKELAELAAELAELQQEAEELEALIAR 231


                   ....*..
gi 1622909132 2007 LERTVKA 2013
Cdd:COG4942    232 LEAEAAA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1977-2158 1.06e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1977 KELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELA--------- 2047
Cdd:COG4942     37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAellralyrl 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2048 ----SFKVLLD-DTQSEAARVLADNLKLKKELQSNKESVKSQmKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKV 2122
Cdd:COG4942    117 grqpPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRAD-LAELAALRAELEAERAELEALLAELEEERAALEALKA 195

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1622909132 2123 HLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAA 2158
Cdd:COG4942    196 ERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2647-2873 1.14e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2647 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDEL 2726
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2727 KRKYDASLKELAQLKEQQGLLnrerhALLSETTFsmdLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSK 2806
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLA-----LLLSPEDF---LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 2807 AMASLQNERDHLWNELEKFRKSEEGKQRSAAQpatslaEVQSLKKAMSSLQNDRDRLLKELKNLQQQ 2873
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIARLEAE 235
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
669-1183 1.28e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  669 FHKAQeiyeknldeKAKEISNLNQLIEEF-------KKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEmn 741
Cdd:COG4913    197 LHKTQ---------SFKPIGDLDDFVREYmleepdtFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYA-- 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  742 lAEAERQRRFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAE 821
Cdd:COG4913    266 -AARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  822 R--------VRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSL 893
Cdd:COG4913    345 ReierlereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELREL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  894 GVEIKTLKE-QLNLLSRAEEAKKE-------------------QVEEDNE------------------------------ 923
Cdd:COG4913    425 EAEIASLERrKSNIPARLLALRDAlaealgldeaelpfvgeliEVRPEEErwrgaiervlggfaltllvppehyaaalrw 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  924 -------------VVSGLKQNYDEMS--PAGLISK-------------EELQHEFDLLKKENEQRKRKLQAAL------- 968
Cdd:COG4913    505 vnrlhlrgrlvyeRVRTGLPDPERPRldPDSLAGKldfkphpfrawleAELGRRFDYVCVDSPEELRRHPRAItragqvk 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  969 -------------INRKELL-----QRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEI- 1029
Cdd:COG4913    585 gngtrhekddrrrIRSRYVLgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVa 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1030 SLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQT---LQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDS 1106
Cdd:COG4913    665 SAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELeeeLDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR 744

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 1107 VALVketvvisppgtdsgehwkPELEEKILALEKEKeqLQKKLQEALTSRkaiLKKAQEKERHLREELKQQKDDYNR 1183
Cdd:COG4913    745 LELR------------------ALLEERFAAALGDA--VERELRENLEER---IDALRARLNRAEEELERAMRAFNR 798
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 677-874 1.34e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  677 EKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKelsvvtELRAQVRQLEMNLAEAERQRRFDYESQ 756
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR------ALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  757 TAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQA 836
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1622909132  837 LSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTE 874
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 796-1092 1.36e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.61  E-value: 1.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  796 SEQSTLIRSLQSQ--LQNKESEVLEGAERVRHISSKVEELSQALS--QKELEIAKMDQLLLE--KKRDVETLQQTIEEKD 869
Cdd:PRK05771    16 SYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDklRSYLPKLNPLREEKKkvSVKSLEELIKDVEEEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  870 QQVTEISFSMTEKMVQLNEEKFSLGVEIKTLK--EQLNLlsraeEAKKEQveeDNEVVSGLkqnydemspAGLISKEELQ 947
Cdd:PRK05771    96 EKIEKEIKELEEEISELENEIKELEQEIERLEpwGNFDL-----DLSLLL---GFKYVSVF---------VGTVPEDKLE 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  948 HEFDLLKKENE----QRKRKLQAALINRKELLQRVsrlEEELANLkDQSKKEIPlsesERGEVEEdkenkEYSEkcvtsk 1023
Cdd:PRK05771   159 ELKLESDVENVeyisTDKGYVYVVVVVLKELSDEV---EEELKKL-GFERLELE----EEGTPSE-----LIRE------ 219

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909132 1024 cqeieisLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQidLLQAEISENQVIIQ 1092
Cdd:PRK05771   220 -------IKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELERAEA--LSKFLKTDKTFAIE 279
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2412-2630 1.36e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2412 ETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsvILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2491
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR----IAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2492 NSENAKLDAELIQY---------REDLNQVISIKDSQQ--------KQLLEAQLQQNKELKNKYAKLEEKLKESEEANED 2554
Cdd:COG4942     96 RAELEAQKEELAELlralyrlgrQPPLALLLSPEDFLDavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132 2555 LQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQeegtlgiyhAQLKVKEEELQRLSALLSSSQKRITELEEE 2630
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELA---------AELAELQQEAEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2665-2893 1.42e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2665 NETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQ 2744
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2745 gllnRERHALLSETtfsmdlpeensLSYLEKLNQQllsKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEK 2824
Cdd:COG4942    100 ----EAQKEELAEL-----------LRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE 161

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622909132 2825 FRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKEL----KNLQQQYLQINQEITELRPLKAQLQE 2893
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLekelAELAAELAELQQEAEELEALIARLEA 234
46 PHA02562
endonuclease subunit; Provisional
 1802-1962 1.45e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.32  E-value: 1.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1802 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKL-------------LQEEVSKMNLLNQ 1868
Cdd:PHA02562   227 EEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMyekggvcptctqqISEGPDRITKIKD 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1869 QIQEELSRVTKLKETAEEEKDDLEERLMNQ--LAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVK 1946
Cdd:PHA02562   307 KLKELQHSLEKLDTAIDELEEIMDEFNEQSkkLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386

                          170
                   ....*....|....*.
gi 1622909132 1947 EKTKVESEIRKEYLEK 1962
Cdd:PHA02562   387 ELDKIVKTKSELVKEK 402
PTZ00121 PTZ00121
MAEBL; Provisional
 828-1212 1.58e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.83  E-value: 1.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  828 SKVEELSQALSQKELEIAKMDQlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlneekfslgvEIKTLKEQLNLL 907
Cdd:PTZ00121  1366 AEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAKK------------KADEAKKKAEEK 1430

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  908 SRAEEAKKeQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAalinrKELLQRVSRLEEELAN 987
Cdd:PTZ00121  1431 KKADEAKK-KAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA-----KKKAEEAKKKADEAKK 1504

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  988 LKDQSKKEIPLSESERG-EVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEM 1066
Cdd:PTZ00121  1505 AAEAKKKADEAKKAEEAkKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAE 1584

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1067 NQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKEtvvisppgtdsgEHWKPELEEKILALEKEKEQLQ 1146
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE------------EKKKVEQLKKKEAEEKKKAEEL 1652

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132 1147 KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1212
Cdd:PTZ00121  1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA 1718
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1545-1957 1.81e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1545 LEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEillqSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1624
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEE----EYAELQEELEELEEELEELEAELEELREELEKLEK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1625 NKKETEKQLQEAEKEMEEMKEKMR-KFAKSKQQKILELEEENDRLRAEVHPAggtAKECMETLLSSNASMKEEVERVKME 1703
Cdd:COG4717    124 LLQLLPLYQELEALEAELAELPERlEELEERLEELRELEEELEELEAELAEL---QEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1704 YETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPA---- 1779
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAgvlf 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1780 --------CSESVPSENSANPAVSEDVSSHDEINNYLQQI--DQLKERIAGLEEEKQKNKEFSQTLEnERNALLSQISTK 1849
Cdd:COG4717    281 lvlgllalLFLLLAREKASLGKEAEELQALPALEELEEEEleELLAALGLPPDLSPEELLELLDRIE-ELQELLREAEEL 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1850 DGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER--LMNQLAELNGSIGNYCQDVTDAQIKNELLESEM 1927
Cdd:COG4717    360 EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELeeLEEQLEELLGELEELLEALDEEELEEELEELEE 439

                          410       420       430
                   ....*....|....*....|....*....|
gi 1622909132 1928 KnlkkcVSELEEEKQQLVKEKTKVESEIRK 1957
Cdd:COG4717    440 E-----LEELEEELEELREELAELEAELEQ 464
PTZ00121 PTZ00121
MAEBL; Provisional
 671-1211 1.95e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 1.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  671 KAQEIYEKNLDEKAKEISNLNQLIEEFKK----NADNNSSAFTALSEERDQLLAQVKELSVVTELRA--QVRQLEMNLAE 744
Cdd:PTZ00121  1231 KAEEAKKDAEEAKKAEEERNNEEIRKFEEarmaHFARRQAAIKAEEARKADELKKAEEKKKADEAKKaeEKKKADEAKKK 1310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  745 AERQRRFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEG-AERV 823
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKkAEEK 1390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  824 R---HISSKVEEL---SQALSQKELEIAKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGV 895
Cdd:PTZ00121  1391 KkadEAKKKAEEDkkkADELKKAAAAKKKADEAKkkAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  896 EIKTLKEQLNLLSRAEEAKKeQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKrklqAALINRKELL 975
Cdd:PTZ00121  1471 KADEAKKKAEEAKKADEAKK-KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK----ADEAKKAEEK 1545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  976 QRVSRLEEELANLKDQSKKEIplsESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAA 1055
Cdd:PTZ00121  1546 KKADELKKAEELKKAEEKKKA---EEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1056 E-----EQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvispPGTDSGEHWKPE 1130
Cdd:PTZ00121  1623 EelkkaEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE-----DEKKAAEALKKE 1697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1131 LEEKilaleKEKEQLQKKLQEALTSRKAiLKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVR 1210
Cdd:PTZ00121  1698 AEEA-----KKAEELKKKEAEEKKKAEE-LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771


                   .
gi 1622909132 1211 E 1211
Cdd:PTZ00121  1772 E 1772
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1047-1488 2.20e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 2.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1047 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPPGTDsgeh 1126
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLE---- 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1127 wkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1206
Cdd:COG4717    150 ---ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1207 IQVRESIDGKLPSPDQQ--EWCSPTPGLEEPLFKATEQHHTQPVLESNLCP----------------DWPSHSEDASALQ 1268
Cdd:COG4717    227 EELEQLENELEAAALEErlKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlflvlgllallflllAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1269 GGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESsql 1348
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVED--- 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1349 qiagLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEdlikalHTQLEMQAKEHDERIKQLQV 1428
Cdd:COG4717    384 ----EEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE------LEELEEELEELEEELEELRE 453

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1429 ELCEMKQKPEEIEEESRAkQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKS 1488
Cdd:COG4717    454 ELAELEAELEQLEEDGEL-AELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1358-2290 2.22e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.09  E-value: 2.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1358 ELQPELDELQKlISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKP 1437
Cdd:pfam01576    6 EMQAKEEELQK-VKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1438 EEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLAD----VESHVSAQNKEKDRVLGRLAll 1513
Cdd:pfam01576   85 EEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEdillLEDQNSKLSKERKLLEERIS-- 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1514 qeERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYEN 1593
Cdd:pfam01576  163 --EFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAK 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1594 VSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEEND------R 1667
Cdd:pfam01576  241 KEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDttaaqqE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1668 LRAEVHPAGGTAKECMETLLSSN---------------ASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQL 1732
Cdd:pfam01576  321 LRSKREQEVTELKKALEEETRSHeaqlqemrqkhtqalEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAK 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1733 ESNVSKQANLEA-----TEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNY 1807
Cdd:pfam01576  401 QDSEHKRKKLEGqlqelQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEE 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1808 LQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETA--- 1884
Cdd:pfam01576  481 TRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALtqq 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1885 EEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQ 1964
Cdd:pfam01576  561 LEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALS 640

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1965 GAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQA 2044
Cdd:pfam01576  641 LARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV 720

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2045 ELASFKVLLD------DTQSE--------AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQA---EEKHLKEK 2107
Cdd:pfam01576  721 NMQALKAQFErdlqarDEQGEekrrqlvkQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAAnkgREEAVKQL 800

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2108 KNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKW------- 2180
Cdd:pfam01576  801 KKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGasgksal 880

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2181 ---ERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQtevqlqqkvcdTLQGENKE 2257
Cdd:pfam01576  881 qdeKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQ-----------QLERQNKE 949

                          970       980       990
                   ....*....|....*....|....*....|....
gi 1622909132 2258 LLSQLEETRHLYHNSQ-NELAKLESELNILKDQL 2290
Cdd:pfam01576  950 LKAKLQEMEGTVKSKFkSSIAALEAKIAQLEEQL 983
mukB PRK04863
chromosome partition protein MukB;
2664-2987 2.23e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 2.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2664 RNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDH------------------------- 2718
Cdd:PRK04863   292 RRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQqekieryqadleeleerleeqnevv 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2719 --ANEELDELKRKYDASLKELAQLKEQ-----QGLLNRERHAL-----------LSETTFSMDLPEENSLSYLEKLNQQL 2780
Cdd:PRK04863   372 eeADEQQEENEARAEAAEEEVDELKSQladyqQALDVQQTRAIqyqqavqalerAKQLCGLPDLTADNAEDWLEEFQAKE 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2781 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQN-----ERDHLWNE-LEKFRKSEEgkQRSAAQPATSL-AEVQSLKKAM 2853
Cdd:PRK04863   452 QEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKiagevSRSEAWDVaRELLRRLRE--QRHLAEQLQQLrMRLSELEQRL 529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2854 sSLQNDRDRLLKELKNLQQQYLQINQEITELR-PLKAQLQEYQDKTKTFQIMQEELRQENLSWQHELHQLRMEKSSW-EI 2931
Cdd:PRK04863   530 -RQQQRAERLLAEFCKRLGKNLDDEDELEQLQeELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWlAA 608

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909132 2932 HER--RMKEQYLMAISDKDQQVSHLQNLIRELRS-------SSSQAQPLKVQYQRQASPETSASP 2987
Cdd:PRK04863   609 QDAlaRLREQSGEEFEDSQDVTEYMQQLLEREREltverdeLAARKQALDEEIERLSQPGGSEDP 673
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1813-2144 2.24e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.04  E-value: 2.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1813 QLKERIAGLEEEKQKNKEFSQTLENERNALLSQIST-KDGELKLLQEEVSKMNLLNQQIQEELSRVTKlketaEEEKDDL 1891
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKaRQAEMDRQAAIYAEQERMAMERERELERIRQ-----EERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1892 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepg 1971
Cdd:pfam17380  363 ERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARK-VKILEEERQRKIQQQKVEMEQIRAEQEEARQ------- 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1972 nkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALErtvkalefvqtesQKDLEITKENLAQAVEHRKKAQAELASFKV 2051
Cdd:pfam17380  435 -----REVRRLEEERAREMERVRLEEQERQQQVERLR-------------QQEEERKRKKLELEKEKRDRKRAEEQRRKI 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2052 LLDDTQSEAARVLADNLK---LKKELQSNKESVKSQMKQKDEDLERRleqaEEKHLKEKKNMQEKLDALRREKVHLEETI 2128
Cdd:pfam17380  497 LEKELEERKQAMIEEERKrklLEKEMEERQKAIYEEERRREAEEERR----KQQEMEERRRIQEQMRKATEERSRLEAME 572

                          330
                   ....*....|....*.
gi 1622909132 2129 GEIQVTLNKKDKEIQQ 2144
Cdd:pfam17380  573 REREMMRQIVESEKAR 588
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2269-2874 2.32e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.98  E-value: 2.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2269 YHNSQNELAKLESELNILKDqltdlsnSLEKCKEQKENLEGIIRQQEAdiqnskfsyeqletdlqasrELTSRLHEeinm 2348
Cdd:PRK03918   160 YENAYKNLGEVIKEIKRRIE-------RLEKFIKRTENIEELIKEKEK--------------------ELEEVLRE---- 208

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2349 keqkmISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKEniqqKAQL 2428
Cdd:PRK03918   209 -----INEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKE----IEEL 278

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2429 DSFVKSMSSLQNDRDRivgdYQQLEERHLSVILEKDQLIQEAAaennKLKEEIRGLRSHMDDLNSENAKLDAELIQYRED 2508
Cdd:PRK03918   279 EEKVKELKELKEKAEE----YIKLSEFYEEYLDELREIEKRLS----RLEEEINGIEERIKELEEKEERLEELKKKLKEL 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2509 LNQVISIKDSQQK-QLLEAQLQQNKELKNKYAKL-----EEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQ 2582
Cdd:PRK03918   351 EKRLEELEERHELyEEAKAKKEELERLKKRLTGLtpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2583 LT----------RQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEEL-----VCVQKEAAKKVGEIED 2647
Cdd:PRK03918   431 LKkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLkkeseLIKLKELAEQLKELEE 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2648 KLKK-----------ELKHLHHDAGIMRNETETAE---ERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSmsslq 2713
Cdd:PRK03918   511 KLKKynleelekkaeEYEKLKEKLIKLKGEIKSLKkelEKLEELKKKLAELEKKLDELEEELAELLKELEELGFE----- 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2714 nSRDHANEELDELKRKYDASLKELAQLKEQQGLLNR-ERHALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHlss 2792
Cdd:PRK03918   586 -SVEELEERLKELEPFYNEYLELKDAEKELEREEKElKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY--- 661

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2793 qlEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRlLKELKNLQQ 2872
Cdd:PRK03918   662 --EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREK-VKKYKALLK 738


                   ..
gi 1622909132 2873 QY 2874
Cdd:PRK03918   739 ER 740
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2076-2754 2.34e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.14  E-value: 2.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2076 SNKESVKSQMKQKDEDLERRLEqaEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQ 2155
Cdd:pfam12128  207 EDDGVVPPKSRLNRQQVEHWIR--DIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQET 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2156 LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEEncsvlkDQLRQMSIHMEELKINISRLEhdkqiwes 2235
Cdd:pfam12128  285 SAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALED------QHGAFLDADIETAAADQEQLP-------- 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2236 KAQTEVQLQQKVCDTLQGENKELlSQLEETRHLYHNSQN--ELAKLESELNILKDQLTDLsnsLEKCKEQKENLEGIIRQ 2313
Cdd:pfam12128  351 SWQSELENLEERLKALTGKHQDV-TAKYNRRRSKIKEQNnrDIAGIKDKLAKIREARDRQ---LAVAEDDLQALESELRE 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2314 QeADIQNSKFSYEQLETDLQASrELTSRLHEEINMKEQKMisllsgKEEAIQVAIAELRQQHDKEIKELENLLSQEEEEN 2393
Cdd:pfam12128  427 Q-LEAGKLEFNEEEYRLKSRLG-ELKLRLNQATATPELLL------QLENFDERIERAREEQEAANAEVERLQSELRQAR 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2394 IVLEEENKKAVDKTNQLMETLNAIkkeniqQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAE 2473
Cdd:pfam12128  499 KRRDQASEALRQASRRLEERQSAL------DELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2474 NNKLKEEIRGLRSHMDDLN-SENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEAN 2552
Cdd:pfam12128  573 SVGGELNLYGVKLDLKRIDvPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNAR 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2553 EDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKE-------EELQRLSALLSSSQKRIT 2625
Cdd:pfam12128  653 LDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEqkreartEKQAYWQVVEGALDAQLA 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2626 ELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDagimrnetetaEERVAELARDLVEMEQKLLMVTKENKDLTaQIQSF 2705
Cdd:pfam12128  733 LLKAAIAARRSGAKAELKALETWYKRDLASLGVD-----------PDVIAKLKREIRTLERKIERIAVRRQEVL-RYFDW 800

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622909132 2706 GRSMSSLQnsRDHANEELDELKRKYDASLKELAQLKEQQGL----LNRERHAL 2754
Cdd:pfam12128  801 YQETWLQR--RPRLATQLSNIERAISELQQQLARLIADTKLrrakLEMERKAS 851
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2645-2903 3.11e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.46  E-value: 3.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2645 IEDKLKKELKHLHhDAGIMRNE---TETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGR-SMSSLQNSRDHAN 2720
Cdd:PRK05771    14 LKSYKDEVLEALH-ELGVVHIEdlkEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKvSVKSLEELIKDVE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2721 EELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYL---------EKLNQQLLSKDEQLLHLS 2791
Cdd:PRK05771    93 EELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGNFDLDLSLLLGFKYVsvfvgtvpeDKLEELKLESDVENVEYI 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2792 SQLEDSYNQVQSFSKAMASLQNE--RDHlwnELEKFRKSEEGkqrsaaqpaTSLAEVQSLKKAMSSLQNDRDRLLKELKN 2869
Cdd:PRK05771   173 STDKGYVYVVVVVLKELSDEVEEelKKL---GFERLELEEEG---------TPSELIREIKEELEEIEKERESLLEELKE 240

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1622909132 2870 LQQQYLQINQEITELRPLKAQLQEYQDKT----KTFQI 2903
Cdd:PRK05771   241 LAKKYLEELLALYEYLEIELERAEALSKFlktdKTFAI 278
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1735-2141 3.42e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.43  E-value: 3.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1735 NVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPAC-SESVPSENSANPAVSEDVSSHDEINNYLQQIDQ 1813
Cdd:PLN02939    41 GFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELpQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1814 LKERIAGLEEEkqknkEFSQTLEN-ERNALLsqistkdgelkllqeevskMNLLNQQIQEELSRVTKLKETAEEEKDDLE 1892
Cdd:PLN02939   121 DGEQLSDFQLE-----DLVGMIQNaEKNILL-------------------LNQARLQALEDLEKILTEKEALQGKINILE 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1893 ERLMNQLAELNGSignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEkiqgaqkepgn 1972
Cdd:PLN02939   177 MRLSETDARIKLA--------AQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENML----------- 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1973 kshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDL----EITKENLAQAVEhrkkaqaelaS 2048
Cdd:PLN02939   238 ---LKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVsklsPLQYDCWWEKVE----------N 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2049 FKVLLDDTQSE---AARVLADNLKLKKELQSNKESVKSQMKQKD-----EDLERRLEQAEEKHLKEKKNMQEKLDAlrre 2120
Cdd:PLN02939   305 LQDLLDRATNQvekAALVLDQNQDLRDKVDKLEASLKEANVSKFssykvELLQQKLKLLEERLQASDHEIHSYIQL---- 380

                          410       420
                   ....*....|....*....|.
gi 1622909132 2121 kvhLEETIGEIQVTLNKKDKE 2141
Cdd:PLN02939   381 ---YQESIKEFQDTLSKLKEE 398
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 762-993 4.10e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  762 LLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE 841
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  842 LEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEI----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAE 911
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  912 EAKKEQVEEDNEVVSGLKQNYDEMspaglisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQ 991
Cdd:COG4942    170 EAERAELEALLAELEEERAALEAL-------KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242


                   ..
gi 1622909132  992 SK 993
Cdd:COG4942    243 TP 244
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 1868-2429 4.26e-04

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 46.36  E-value: 4.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1868 QQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSElEEEKQQLVKE 1947
Cdd:PTZ00440   479 EKDSMDSKEKKESSDSNYQEKVDELLQIINSIKEKNNIVNNNFKNIEDYYITIEGLKNEIEGLIELIKY-YLQSIETLIK 557

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1948 KTKVESEIRKEYLEKIQGAQkepGNKSHAKELQELLKEKQ---QEVKQLQKDCIRYQEKISALERTVKAL--EFVQTESQ 2022
Cdd:PTZ00440   558 DEKLKRSMKNDIKNKIKYIE---ENVDHIKDIISLNDEIDniiQQIEELINEALFNKEKFINEKNDLQEKvkYILNKFYK 634

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2023 KDLEITKENLAQAVEHRKKAQAELAS---FKVLLDDTQSEAARVL---ADNL-----KLKKELQSNKESVKSQMKQKDED 2091
Cdd:PTZ00440   635 GDLQELLDELSHFLDDHKYLYHEAKSkedLQTLLNTSKNEYEKLEfmkSDNIdniikNLKKELQNLLSLKENIIKKQLNN 714

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2092 LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLE---ETIGEIQ----VTLNKKDKEI-------QQVQENLDSTVAQLA 2157
Cdd:PTZ00440   715 IEQDISNSLNQYTIKYNDLKSSIEEYKEEEEKLEvykHQIINRKnefiLHLYENDKDLpdgkntyEEFLQYKDTILNKEN 794

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2158 AFTKSMSSLQDDRDRVIDEAKKWE-----------------RKFSDAIQTKEEEIRLKE------ENCSVLKDQLRQMSI 2214
Cdd:PTZ00440   795 KISNDINILKENKKNNQDLLNSYNiliqkleahtekndeelKQLLQKFPTEDENLNLKElekefnENNQIVDNIIKDIEN 874

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2215 H------MEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESEL-NILK 2287
Cdd:PTZ00440   875 MnkniniIKTLNIAINRSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDNIIQKNEKLNLLNNLNKEKEKIEKQLsDTKI 954

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2288 DQL-TDLSNSLEKCKEQKENLEGI-------IRQQEADIQNSKFSYEQLETDLQAsreLTSRLHEEINMKEQKMISLLSG 2359
Cdd:PTZ00440   955 NNLkMQIEKTLEYYDKSKENINGNdgthlekLDKEKDEWEHFKSEIDKLNVNYNI---LNKKIDDLIKKQHDDIIELIDK 1031

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2360 KEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLD 2429
Cdd:PTZ00440  1032 LIKEKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEALLKKIDENKNKLI 1101
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1869-2502 4.44e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.37  E-value: 4.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1869 QIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcvSELEEEKQQLVKEK 1948
Cdd:pfam12128  273 LIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLP 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1949 TkVESEIrkEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQL----QKDCIRYQEKISALERTVKALEFVQTESQKD 2024
Cdd:pfam12128  351 S-WQSEL--ENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIagikDKLAKIREARDRQLAVAEDDLQALESELREQ 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2025 LEITKENLAQAVEHRKKAQAELasfKVLLDDTQSEaarvladnlklkKELQSNKESVKSQMKQKDEDLERR---LEQAEE 2101
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGEL---KLRLNQATAT------------PELLLQLENFDERIERAREEQEAAnaeVERLQS 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2102 KHLKEKKNMQEKLDALRREKVHLEETIGeiqvtlnkkdkEIQQVQENLDSTVAQLAAFTKSMSSL-QDDRDRVIDEAKKW 2180
Cdd:pfam12128  493 ELRQARKRRDQASEALRQASRRLEERQS-----------ALDELELQLFPQAGTLLHFLRKEAPDwEQSIGKVISPELLH 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2181 ErkfSDAIQTKEEEIRLKEENCSVLKDQLRQMSI-----HMEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGEN 2255
Cdd:pfam12128  562 R---TDLDPEVWDGSVGGELNLYGVKLDLKRIDVpewaaSEEELRERLDKAEEALQ----SAREKQAAAEEQLVQANGEL 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2256 KELLSQLEETRHLYHNSQNELAKLESELNILKDQLTD-LSNSLEKCKEQKENLEGIIRQQEADIQNSkfsyeqletdLQA 2334
Cdd:pfam12128  635 EKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKaLAERKDSANERLNSLEAQLKQLDKKHQAW----------LEE 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2335 SRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETL 2414
Cdd:pfam12128  705 QKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2415 NAIKKeNIQQKAQLDSFVKSMSSLQNDRDRIvgdyqQLEERHLSVILEKDQL---IQEAAAENNKLKEEIRGLRSHMDDL 2491
Cdd:pfam12128  785 ERIAV-RRQEVLRYFDWYQETWLQRRPRLAT-----QLSNIERAISELQQQLarlIADTKLRRAKLEMERKASEKQQVRL 858

                          650
                   ....*....|.
gi 1622909132 2492 NSENAKLDAEL 2502
Cdd:pfam12128  859 SENLRGLRCEM 869
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 678-1215 4.60e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.17  E-value: 4.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  678 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELsvvtelRAQVRQLEMNLAEAERQRRFDYESQT 757
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDL------KKQKEELENELNLLEKEKLNIQKNID 190

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  758 AHHNLLTEQIHSLSIeAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQAL 837
Cdd:TIGR04523  191 KIKNKLLKLELLLSN-LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  838 SQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKF---------------SLGVEIKTLKE 902
Cdd:TIGR04523  270 SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLeeiqnqisqnnkiisQLNEQISQLKK 349

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  903 QLNLLSRAEEAKKEQVEEDNEVVSGLK---QNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS 979
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKkenQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  980 RLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEiSLKQTISEKEVELEHIRKDLEEKMAAEEQL 1059
Cdd:TIGR04523  430 RLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSIN-KIKQNLEQKQKELKSKEKELKKLNEEKKEL 508

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1060 QALVKEMNQTLQDKTNQIDLLQAEISE-NQVIIQKLTTSNTDASDGDSVALVKEtvvisppgTDSGEHWKPELEEKILAL 1138
Cdd:TIGR04523  509 EEKVKDLTKKISSLKEKIEKLESEKKEkESKISDLEDELNKDDFELKKENLEKE--------IDEKNKEIEELKQTQKSL 580

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 1139 EKEKEQLQKKLQEALTSRKAILKKAQEKERhLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1215
Cdd:TIGR04523  581 KKKQEEKQELIDQKEKEKKDLIKEIEEKEK-KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1909-2593 4.69e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.26  E-value: 4.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1909 YCQDVTDAQIK----NELLESEMKNLKKCVSELEEEKQQLVKEKTKVeSEIRKEYLEKIQGAQKEPGNKSH----AKELQ 1980
Cdd:pfam15921   83 YSHQVKDLQRRlnesNELHEKQKFYLRQSVIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHeleaAKCLK 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1981 E-LLKEKQQEVKQLQKDCIRYQEKISALERTVkaLEFVQTESQKdleITKENLAQAVEHRKKAQAelasFKVLLDDTQSE 2059
Cdd:pfam15921  162 EdMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL--VDFEEASGKK---IYEHDSMSTMHFRSLGSA----ISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2060 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2139
Cdd:pfam15921  233 ISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQN 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2140 KEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDeaKKWERKFSDAIQTKEEEIRLKEENCSvLKDQLRQM--SIHME 2217
Cdd:pfam15921  313 SMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELE--KQLVLANSELTEARTERDQFSQESGN-LDDQLQKLlaDLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2218 ELKINISRlEHDKQIWESKAQTEVQLQ-------------QKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESeln 2284
Cdd:pfam15921  390 EKELSLEK-EQNKRLWDRDTGNSITIDhlrrelddrnmevQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSS--- 465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2285 iLKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKE--- 2361
Cdd:pfam15921  466 -LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDhlr 544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2362 ------EAIQVAIAE-------LRQQhdkeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQL 2428
Cdd:pfam15921  545 nvqtecEALKLQMAEkdkvieiLRQQ----IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKI 620

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2429 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQE---AAAENNKLKEEI----RGLRSHMDDLNSENAKLDAE 2501
Cdd:pfam15921  621 RELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTTNKLKMQ 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2502 LIQYREDLNQVISIKDSQQK---QLLEAQLQQNKELKNKYAKLEEKLKESEEANEDL---QRSSNALQEEKRDLSKEIES 2575
Cdd:pfam15921  701 LKSAQSELEQTRNTLKSMEGsdgHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMtnaNKEKHFLKEEKNKLSQELST 780

                          730
                   ....*....|....*...
gi 1622909132 2576 LKVSVSQLTRQVTALQEE 2593
Cdd:pfam15921  781 VATEKNKMAGELEVLRSQ 798
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2235-2444 4.91e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2235 SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQ 2314
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2315 EADIQ-NSKFSYEQL----ETDLQASRELtsRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQE 2389
Cdd:COG4942    110 LRALYrLGRQPPLALllspEDFLDAVRRL--QYLKYLAPARREQAEELRADLAELAALRAELEAER-AELEALLAELEEE 186

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909132 2390 EEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDR 2444
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1956-2149 5.27e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 5.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1956 RKEYLEKIQGaQKEPGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERTVKALEFVQTESQKDLEITK--ENLA 2033
Cdd:COG4717     54 EADELFKPQG-RKPELNLKELKELEEELKEAEEKEEEYAEL----QEELEELEEELEELEAELEELREELEKLEklLQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2034 QAVEHRKKAQAELASFKVLLDDTQSEAARVladnlklkKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEK 2113
Cdd:COG4717    129 PLYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1622909132 2114 LDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2149
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENEL 236
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 629-1205 5.61e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 46.20  E-value: 5.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  629 ELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAqeIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAF 708
Cdd:TIGR01612 1119 DIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLL 1196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  709 TALSE-ERDQL-LAQVKELSVVTELRAQVRQLEmNLAEAERQRRFDYESQTAHHNLLTE------QIHSLSIEAKSKDVK 780
Cdd:TIGR01612 1197 NEIAEiEKDKTsLEEVKGINLSYGKNLGKLFLE-KIDEEKKKSEHMIKAMEAYIEDLDEikekspEIENEMGIEMDIKAE 1275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  781 IEVLQNELDDVQLQFSEQSTLIRSLqSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVET 860
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNI 1354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  861 LQ-QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLlsraeEAKKEQVEE--DNEVVSGLKQNYDEMSP 937
Cdd:TIGR01612 1355 LKlNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINL-----EECKSKIEStlDDKDIDECIKKIKELKN 1429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  938 AGLISKEELQHEFDLLKKENEQrkrklqaALINRKELLQRVSRLEEELANLKDQSKKEIPLSesergeVEEDKENKEYSE 1017
Cdd:TIGR01612 1430 HILSEESNIDTYFKNADENNEN-------VLLLFKNIEMADNKSQHILKIKKDNATNDHDFN------INELKEHIDKSK 1496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1018 KCVTskcqEIEISLKQTISEKEVeLEHIRKDLEEKMAAEEQLqALVKEMNQTLQDKTNQID---------LLQAEISE-- 1086
Cdd:TIGR01612 1497 GCKD----EADKNAKAIEKNKEL-FEQYKKDVTELLNKYSAL-AIKNKFAKTKKDSEIIIKeikdahkkfILEAEKSEqk 1570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1087 -NQVIIQKLTTSNTDASDGDS-VALVKETVVISPpgtdsgehwkpeLEEKILALEkekeQLQKKLQEALTSRKAILKKAQ 1164
Cdd:TIGR01612 1571 iKEIKKEKFRIEDDAAKNDKSnKAAIDIQLSLEN------------FENKFLKIS----DIKKKINDCLKETESIEKKIS 1634

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1622909132 1165 EKERHLRE-ELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1205
Cdd:TIGR01612 1635 SFSIDSQDtELKENGDNLNSLQEFLESLKDQKKNIEDKKKEL 1676
PRK12704 PRK12704
phosphodiesterase; Provisional
 2038-2200 5.91e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.54  E-value: 5.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2038 HRKKAQAELASFKVLLDDTQsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERR--LEQAEEKHLKEKKNMQEKLD 2115
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2116 ALRREKVHLEETIGEiqvtLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDD--RDRVIDEAKKwERKFSDAIQTKEE 2193
Cdd:PRK12704   104 LLEKREEELEKKEKE----LEQKQQELEKKEEELEELIEEQLQELERISGLTAEeaKEILLEKVEE-EARHEAAVLIKEI 178


                   ....*..
gi 1622909132 2194 EIRLKEE 2200
Cdd:PRK12704   179 EEEAKEE 185
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1272-1472 6.72e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 6.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1272 SVAQIKAQLKEIETEKEKLELKISS--TTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQ 1349
Cdd:COG3206    176 ALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1350 IAGLEHLRELQPELDELQKLISEKEEdvsyLSGQLREKEAALTKIQTEIIEQEDLIKA----LHTQLEMQAKEHDERIKQ 1425
Cdd:COG3206    256 LPELLQSPVIQQLRAQLAELEAELAE----LSARYTPNHPDVIALRAQIAALRAQLQQeaqrILASLEAELEALQAREAS 331

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622909132 1426 LQVELCEMKQKPEEIEEESRAKQQIQRKLQAA------LISRKEALKENKSLQ 1472
Cdd:COG3206    332 LQAQLAQLEARLAELPELEAELRRLEREVEVArelyesLLQRLEEARLAEALT 384
46 PHA02562
endonuclease subunit; Provisional
 2507-2743 7.65e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.01  E-value: 7.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2507 EDL--NQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRD----LSKEIESLKVSV 2580
Cdd:PHA02562   157 EDLldISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKTIKAEI 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2581 SQLTRQVTALQEEGtlGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVC------------VQKEAAKKVGEIEDK 2648
Cdd:PHA02562   237 EELTDELLNLVMDI--EDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCptctqqisegpdRITKIKDKLKELQHS 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2649 LKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQsfgrsmsSLQNSRDHANEELDELKR 2728
Cdd:PHA02562   315 LEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEELAKLQD 386

                          250
                   ....*....|....*
gi 1622909132 2729 KYDASLKELAQLKEQ 2743
Cdd:PHA02562   387 ELDKIVKTKSELVKE 401
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 206-420 8.26e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 8.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  206 LLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLR---NTVETE 282
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  283 REESKILLEKMELEVAER---------------KLSFHNLQEEMR--HLLEQLEQAGQAQAE-LESRYSALEQKhKAEME 344
Cdd:COG4942     92 IAELRAELEAQKEELAELlralyrlgrqpplalLLSPEDFLDAVRrlQYLKYLAPARREQAEeLRADLAELAAL-RAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132  345 EKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQ 420
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2786-3058 8.64e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 8.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2786 QLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKS--EEGKQRSAAQpatslAEVQSLKKAMSSLQNDRDRL 2863
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLEleELELELEEAQ-----AEEYELLAELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2864 LKELKNLQQQYLQINQEITELRP----LKAQLQEYQDKTKTFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQ 2939
Cdd:COG1196    308 EERRRELEERLEELEEELAELEEeleeLEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2940 YLMAISDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASPETSASPdgsqnliyETELLRNQLNDSLKEIHQKELRIQ 3019
Cdd:COG1196    388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE--------EEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1622909132 3020 QLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLN 3058
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1340-1703 8.72e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.28  E-value: 8.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1340 QQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYL---SGQLREKEAALTKIQTEIIEQEDLiKALHTQLEMQA 1416
Cdd:PLN02939    39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSlrtVMELPQKSTSSDDDHNRASMQRDE-AIAAIDNEQQT 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1417 KEHD-ERIKQLQVE-LCEMKQKPEE-IEEESRAKQQIQRKLQAALiSRKEAL-KENKSLQEELSLARDTIEHLTKSLADV 1492
Cdd:PLN02939   118 NSKDgEQLSDFQLEdLVGMIQNAEKnILLLNQARLQALEDLEKIL-TEKEALqGKINILEMRLSETDARIKLAAQEKIHV 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1493 ESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKE---KLVKEIESLKSS---- 1565
Cdd:PLN02939   197 EILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEErvfKLEKERSLLDASlrel 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1566 --KIAESSEWQEKHKELQkeYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETekqlqeaekem 1640
Cdd:PLN02939   277 esKFIVAQEDVSKLSPLQ--YDCWWEKVENLQDLLDRATNQVEkaaLVLDQNQDLRDKVDKLEASLKEA----------- 343

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 1641 eemkeKMRKFAKSK----QQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKME 1703
Cdd:PLN02939   344 -----NVSKFSSYKvellQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEESKKRSLE 405
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2484-2686 8.74e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 8.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2484 LRSHMDDLNSENAKLDAELIQYREDLNQvisikdsqqkqlLEAQLQQNKElKNKYAKLEEKLKESEEANEDLQRSSNALQ 2563
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKELEE------------AEAALEEFRQ-KNGLVDLSEEAKLLLQQLSELESQLAEAR 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2564 EEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVG 2643
Cdd:COG3206    233 AELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1622909132 2644 EIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQ 2686
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2428-3031 8.74e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 8.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2428 LDSFVKSM----SSLQNDRDRIVGDYQQLEERHLSVILEKDQL-----IQEAAAENNKLKEEIRGLRSHMDDLNSENAKL 2498
Cdd:COG4913    209 LDDFVREYmleePDTFEAADALVEHFDDLERAHEALEDAREQIellepIRELAERYAAARERLAELEYLRAALRLWFAQR 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2499 DAELIQYREDLNQvisikdsQQKQLLEAQLQQNKELKNKyAKLEEKLKESEEANEDLQRSsNALQEEKRDLSKEIESLKV 2578
Cdd:COG4913    289 RLELLEAELEELR-------AELARLEAELERLEARLDA-LREELDELEAQIRGNGGDRL-EQLEREIERLERELEERER 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2579 SVSQLTRQVTALQEE--GTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDkLKKELKHL 2656
Cdd:COG4913    360 RRARLEALLAALGLPlpASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS-LERRKSNI 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2657 HHDAGIMRNETETA----EER---VAEL---------------------ARDLVEMEQKLLMVTK--ENKDLTAQIQSFG 2706
Cdd:COG4913    439 PARLLALRDALAEAlgldEAElpfVGELievrpeeerwrgaiervlggfALTLLVPPEHYAAALRwvNRLHLRGRLVYER 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2707 --RSMSSLQNSRDHAN---EELD------------ELKRKYD----ASLKELAQLKE---QQGLL--NRERHALlsettf 2760
Cdd:COG4913    519 vrTGLPDPERPRLDPDslaGKLDfkphpfrawleaELGRRFDyvcvDSPEELRRHPRaitRAGQVkgNGTRHEK------ 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2761 sMDLPEENSLSYLEKLN-QQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQnERDHLWNELEKFRKSE---------- 2829
Cdd:COG4913    593 -DDRRRIRSRYVLGFDNrAKLAALEAELAELEEELAEAEERLEALEAELDALQ-ERREALQRLAEYSWDEidvasaerei 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2830 EGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRplkAQLQEYQDKTKTFQIMQEELR 2909
Cdd:COG4913    671 AELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAE---EELDELQDRLEAAEDLARLEL 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2910 QENLswQHELHQLRMEKssweiHERRMKEQYLMAISDKDQQVSHLQNLIRELRSsssqaqplkvQYQRQASPETSASPDG 2989
Cdd:COG4913    748 RALL--EERFAAALGDA-----VERELRENLEERIDALRARLNRAEEELERAMR----------AFNREWPAETADLDAD 810

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 1622909132 2990 SQNLIYETELLRNQLNDSLKEIHQK--ELRIQQLNSKFSQLLEE 3031
Cdd:COG4913    811 LESLPEYLALLDRLEEDGLPEYEERfkELLNENSIEFVADLLSK 854
PRK12704 PRK12704
phosphodiesterase; Provisional
 1626-1769 1.05e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.77  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1626 KKETEKQLQEAEKEMEEMKEKMRKFAKS-KQQKILELEEENDRLRAEVHpaggtaKEcmetLLSSNASMKEEVERVKMEY 1704
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAiKKEALLEAKEEIHKLRNEFE------KE----LRERRNELQKLEKRLLQKE 95

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909132 1705 ETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQ-----MNVT-EEATQSIPGETEDQ 1769
Cdd:PRK12704    96 ENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQeleriSGLTaEEAKEILLEKVEEE 166
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2254-2474 1.07e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2254 ENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQ 2333
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2334 ASRE-LTSRLHEEINMKEQKMISLLSGKEEAIQVA-----IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2407
Cdd:COG4942    101 AQKEeLAELLRALYRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 2408 NQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAEN 2474
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
172-348 1.13e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  172 QTQAEQAAQLssmqQVVREKDARFEtQVRLHEDELLQLVTQADVETEmQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 251
Cdd:COG4913    245 EDAREQIELL----EPIRELAERYA-AARERLAELEYLRAALRLWFA-QRRLELLEAELEELRAELARLEAELERLEARL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  252 TAAEQR----------NQILSQQLQQIEAEHNTL-RNTVETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQ 320
Cdd:COG4913    319 DALREEldeleaqirgNGGDRLEQLEREIERLEReLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEE 398

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1622909132  321 ----AGQAQAELESRYSALEQKHKAEMEEKTS 348
Cdd:COG4913    399 eleaLEEALAEAEAALRDLRRELRELEAEIAS 430
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1279-1956 1.18e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.04  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1279 QLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQInkQGLEIESLKTASHEAEVRAE----SLQQKLESSQLQIAGLE 1354
Cdd:TIGR00606  427 QADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKEL--QQLEGSSDRILELDQELRKAerelSKAEKNSLTETLKKEVK 504

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1355 HLRELQPELDELQKLISEKEEDVSYLSGQLREKEAaLTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMK 1434
Cdd:TIGR00606  505 SLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEM-LTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKS 583

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1435 QKPEEIEEESRakqQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSlADVESHVSAQNKEKDRVLGRLALLQ 1514
Cdd:TIGR00606  584 KEINQTRDRLA---KLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEIEKSSKQRAMLA 659

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1515 EERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEdkekLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENV 1594
Cdd:TIGR00606  660 GATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQE----FISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGR 735

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1595 SNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLqEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHP 1674
Cdd:TIGR00606  736 QSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL-GTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAK 814

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1675 AGGTakecmeTLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLES----NVSKQANLEATEKHDN 1750
Cdd:TIGR00606  815 LQGS------DLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNElkseKLQIGTNLQRRQQFEE 888

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1751 QMNVTEEATQSIPGETED-QDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1829
Cdd:TIGR00606  889 QLVELSTEVQSLIREIKDaKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGK 968

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1830 E-FSQTLENERNALLSQISTKDGELKLLQEEVSKM--NLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGsi 1906
Cdd:TIGR00606  969 DdYLKQKETELNTVNAQLEECEKHQEKINEDMRLMrqDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQ-- 1046

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1907 gnycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR 1956
Cdd:TIGR00606 1047 ----MQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELR 1092
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 652-984 1.25e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  652 QDELERLKSQILELELNFHKAQ---EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKEL-SV 727
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSqelSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELeAR 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  728 VTELRAQVRQLEMNLAEAERQRRFDYESQtahhnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 807
Cdd:TIGR02169  767 IEELEEDLHKLEEALNDLEARLSHSRIPE------IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  808 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 887
Cdd:TIGR02169  841 QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  888 EekfsLGVEIKTLKEQLNLLSRAEEAKKEQVEED---NEVVSGLKQNYDEMSPAGLISKEELQhEFDLLKKENEQRKRKL 964
Cdd:TIGR02169  921 E----LKAKLEALEEELSEIEDPKGEDEEIPEEElslEDVQAELQRVEEEIRALEPVNMLAIQ-EYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|
gi 1622909132  965 QAALINRKELLQRVSRLEEE 984
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKK 1015
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1274-1474 1.26e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1274 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEvfQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSqlqiaGL 1353
Cdd:COG4913    265 AAARERLAELEYLRAALRLWFAQRRLELLEAELE--ELRAELARLEAELERLEARLDALREELDELEAQIRGN-----GG 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1354 EHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1433
Cdd:COG4913    338 DRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1622909132 1434 KQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEE 1474
Cdd:COG4913    418 RRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEA 458
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 2561-2885 1.27e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2561 ALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVcVQKEAAK 2640
Cdd:COG3096    789 ELRAERDELAEQYAKASFDVQKLQRLHQAFSQFVGGHLAVAFAPDPEAELAALRQRRSELERELAQHRAQEQ-QLRQQLD 867

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2641 KVGEIEDKLKKELKHLHHDAgimrneTETAEERVAELARDLVEMEQKLLMVTKENKDLT------AQIQSFGRSMSSLQN 2714
Cdd:COG3096    868 QLKEQLQLLNKLLPQANLLA------DETLADRLEELREELDAAQEAQAFIQQHGKALAqleplvAVLQSDPEQFEQLQA 941

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2715 SRDHANEELDELKRKYDAsLKELAQlkeqqgllnrERHALLSETTFSMdLPEENSLSylEKLNQQLLSKDEQLLHLSSQL 2794
Cdd:COG3096    942 DYLQAKEQQRRLKQQIFA-LSEVVQ----------RRPHFSYEDAVGL-LGENSDLN--EKLRARLEQAEEARREAREQL 1007

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2795 EDSYNQVQSFSKAMASLQNERDHLWNELEKFRK--SEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLK------- 2865
Cdd:COG3096   1008 RQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQelEELGVQADAEAEERARIRRDELHEELSQNRSRRSQLEKqltrcea 1087

                          330       340
                   ....*....|....*....|
gi 1622909132 2866 ELKNLQQQYLQINQEITELR 2885
Cdd:COG3096   1088 EMDSLQKRLRKAERDYKQER 1107
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1872-2534 1.29e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1872 EELSRVTKLKETAEEEKDDLE---------ERLMNQLAELNgsignYCQDVTD---AQIKNELLESEMKNLKKCVSELEE 1939
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEpirelaeryAAARERLAELE-----YLRAALRlwfAQRRLELLEAELEELRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1940 EKQQLVKEKTKVESEIR--KEYLEKIQGAQKEpgnkshakELQELLKEKQQEVKQLQKDCIRYQEKISALERTV----KA 2013
Cdd:COG4913    310 ELERLEARLDALREELDelEAQIRGNGGDRLE--------QLEREIERLERELEERERRRARLEALLAALGLPLpasaEE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2014 LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDL- 2092
Cdd:COG4913    382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELp 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2093 -----------ERRLEQAEEKHLKEKK-NM---QEKLDALRR--EKVHLEETIGEIQVTLNKKDKEIQQVQEN-----LD 2150
Cdd:COG4913    462 fvgelievrpeEERWRGAIERVLGGFAlTLlvpPEHYAAALRwvNRLHLRGRLVYERVRTGLPDPERPRLDPDslagkLD 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2151 S-----------------------TVAQLAAFTKSMSSL----QDDRDRVIDEAKKWERK----FS--DAIQTKEEEIRL 2197
Cdd:COG4913    542 FkphpfrawleaelgrrfdyvcvdSPEELRRHPRAITRAgqvkGNGTRHEKDDRRRIRSRyvlgFDnrAKLAALEAELAE 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2198 KEENCSVLKDQLRQMSIHMEELKINISRLEH-DKQIWESKAQTEVQLQqkvcdtlqgenkelLSQLEETRHLYHNSQNEL 2276
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRlAEYSWDEIDVASAERE--------------IAELEAELERLDASSDDL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2277 AKLESELNILKDQLTDLsnslekcKEQKENLEGIIRQQEADIqnskfsyEQLETDLQASREltsRLHEEINMKEQKMISL 2356
Cdd:COG4913    688 AALEEQLEELEAELEEL-------EEELDELKGEIGRLEKEL-------EQAEEELDELQD---RLEAAEDLARLELRAL 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2357 LSGK--EEAIQVAIAELRQQHDKEIKELENLLSQeeeenivleeenkkavdKTNQLMETLNAIKKENIQQKAQLDSFVKS 2434
Cdd:COG4913    751 LEERfaAALGDAVERELRENLEERIDALRARLNR-----------------AEEELERAMRAFNREWPAETADLDADLES 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2435 MSSLQNDRDRIVGD-----YQQLEErhlsviLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSE--------------- 2494
Cdd:COG4913    814 LPEYLALLDRLEEDglpeyEERFKE------LLNENSIEFVADLLSKLRRAIREIKERIDPLNDSlkripfgpgrylrle 887

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1622909132 2495 -NAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKEL 2534
Cdd:COG4913    888 aRPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRL 928
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2135-2335 1.31e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2135 LNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKfsdaIQTKEEEIRLKEENCSVLKDQLRQMSI 2214
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAE----IDKLQAEIAEAEAEIEERREELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2215 HMEELKINISRLEhdkQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLS 2294
Cdd:COG3883     94 ALYRSGGSVSYLD---VLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1622909132 2295 NSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQAS 2335
Cdd:COG3883    171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAA 211
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1798-2035 1.39e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1798 VSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKmnlLNQQIQEelsRV 1877
Cdd:COG3883     12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAE---AEAEIEE---RR 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1878 TKLKETAEEEKddLEERLMNQLAELNGSignycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEirk 1957
Cdd:COG3883     86 EELGERARALY--RSGGSVSYLDVLLGS-----ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAK--- 155

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909132 1958 eyLEKIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2035
Cdd:COG3883    156 --LAELEALKAE--LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2252-2885 1.46e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.51  E-value: 1.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2252 QGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLegiiRQQEADIQNSKFSYEQLETD 2331
Cdd:PRK01156   137 QGEMDSLISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKL----KSSNLELENIKKQIADDEKS 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2332 LQASRELTSRLHEEINMKEQKMISL------LSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVD 2405
Cdd:PRK01156   213 HSITLKEIERLSIEYNNAMDDYNNLksalneLSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYK 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2406 KTNQLMETLNAIKkeniqqkaQLDSFVKSMSSLQNDrdrivgdyqqleerhlsviLEKDQLIQEAAAENNKLKEEIRGLR 2485
Cdd:PRK01156   293 NRNYINDYFKYKN--------DIENKKQILSNIDAE-------------------INKYHAIIKKLSVLQKDYNDYIKKK 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2486 SHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQkqlleaqlQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEE 2565
Cdd:PRK01156   346 SRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIE--------EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVK 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2566 KRDLSKEIESLKVSVSQLTRqvtalqeegtlgiyhaqlkvKEEELQRLSALLSSSQKRI---TELEEELVcvqKEAAKKV 2642
Cdd:PRK01156   418 LQDISSKVSSLNQRIRALRE--------------------NLDELSRNMEMLNGQSVCPvcgTTLGEEKS---NHIINHY 474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2643 GEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEmeqKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANE- 2721
Cdd:PRK01156   475 NEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEIN---KSINEYNKIESARADLEDIKIKINELKDKHDKYEEi 551

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2722 -------ELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLSSQL 2794
Cdd:PRK01156   552 knrykslKLEDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2795 EDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQY 2874
Cdd:PRK01156   632 NNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRI 711

                          650
                   ....*....|.
gi 1622909132 2875 LQINQEITELR 2885
Cdd:PRK01156   712 NELSDRINDIN 722
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
371-538 1.55e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  371 NSKLLQDKDEQAVQSAQTIEQLEDQLQQKSKEISQFLNRLplQQHETASQTCFPDVynegtqavteeNIASLQKRVVELE 450
Cdd:COG4913    608 NRAKLAALEAELAELEEELAEAEERLEALEAELDALQERR--EALQRLAEYSWDEI-----------DVASAEREIAELE 674

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  451 NEKGALLLSSIELEELKAENEKLSSQITllEAQNRIGEADREVSEisiVDDANKRSSSTEESGQDVLENTFSQKHKELSV 530
Cdd:COG4913    675 AELERLDASSDDLAALEEQLEELEAELE--ELEEELDELKGEIGR---LEKELEQAEEELDELQDRLEAAEDLARLELRA 749


                   ....*...
gi 1622909132  531 LLLEMKEA 538
Cdd:COG4913    750 LLEERFAA 757
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1976-2500 1.97e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.88  E-value: 1.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1976 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERtvkalefvqtesqkdleiTKENLAQAVEHRKKAQAELASFKVLLDD 2055
Cdd:PRK02224   201 EKDLHERLNGLESELAELDEEIERYEEQREQARE------------------TRDEADEVLEEHEERREELETLEAEIED 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2056 TQSEAARVladnlklKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK--EKKNMQEKLDALRREKVHLEETIGEIQV 2133
Cdd:PRK02224   263 LRETIAET-------EREREELAEEVRDLRERLEELEEERDDLLAEAGLDdaDAEAVEARREELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2134 TLNKKDKEIQQVQENldstVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMS 2213
Cdd:PRK02224   336 AAQAHNEEAESLRED----ADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2214 IHMEELKINISRLEhdkqiwESKAQTEVQLQQkVCDTLQgENKELLSQ---------LEETRHL--YHNSQNELAKLESE 2282
Cdd:PRK02224   412 DFLEELREERDELR------EREAELEATLRT-ARERVE-EAEALLEAgkcpecgqpVEGSPHVetIEEDRERVEELEAE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2283 LNILKDQLTDLSNSL-------------EKCKEQKENLEGIIRQQEADIQNSKFSYEQ-------LETDLQASRELTSRL 2342
Cdd:PRK02224   484 LEDLEEEVEEVEERLeraedlveaedriERLEERREDLEELIAERRETIEEKRERAEElreraaeLEAEAEEKREAAAEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2343 HEEINmKEQKMISLLSGKEEAIQVAIAELRQqhdkeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLnaikKENI 2422
Cdd:PRK02224   564 EEEAE-EAREEVAELNSKLAELKERIESLER-----IRTLLAAIADAEDEIERLREKREALAELNDERRERL----AEKR 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2423 QQKAQLDSFVKS--MSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAENNKLkEEIRGLRSHMDDLNSENAKLDA 2500
Cdd:PRK02224   634 ERKRELEAEFDEarIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL-EELEELRERREALENRVEALEA 712
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2529-3050 2.01e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.95  E-value: 2.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2529 QQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLS-------KEIESLKVSVSQLTRQVTALQEEGTLGIYHA 2601
Cdd:pfam15921  138 QSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMlshegvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRS 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2602 QLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLhhdagIMRNETE-TAEERVAELARD 2680
Cdd:pfam15921  218 LGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQL-----ISEHEVEiTGLTEKASSARS 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2681 LVEMEQKLLMVTKENKdlTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELA------------------QLKE 2742
Cdd:pfam15921  293 QANSIQSQLEIIQEQA--RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlanseltearterdQFSQ 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2743 QQGLLNRERHALLSETTfsmdlPEENSLSYLEKLNQQLLSKDE----QLLHLSSQLEDSYNQVQ---------------S 2803
Cdd:pfam15921  371 ESGNLDDQLQKLLADLH-----KREKELSLEKEQNKRLWDRDTgnsiTIDHLRRELDDRNMEVQrleallkamksecqgQ 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2804 FSKAMASLQNERDHLWN--------------------ELEKFRKSEEGKQRSAAQPATSLAE----VQSLKKAMSSLQND 2859
Cdd:pfam15921  446 MERQMAAIQGKNESLEKvssltaqlestkemlrkvveELTAKKMTLESSERTVSDLTASLQEkeraIEATNAEITKLRSR 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2860 RDRLLKELKNLQQQYLQINQEITELRPLKAQLQEyqdKTKTFQIMQEELRQ-ENLSWQH-------ELHQLRMEKsswEI 2931
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAE---KDKVIEILRQQIENmTQLVGQHgrtagamQVEKAQLEK---EI 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2932 HERRMKEQYLMAISDKDQQVshlqnlIRELRSSSSQAQPLKVQYQRQASPETSASPDGSQ---NLIYETELLRNQLNdSL 3008
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAK------IRELEARVSDLELEKVKLVNAGSERLRAVKDIKQerdQLLNEVKTSRNELN-SL 672

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1622909132 3009 KEihQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQ 3050
Cdd:pfam15921  673 SE--DYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2671-2895 2.09e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 2.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2671 EERVAELARDLVEMEQKLLMVTKENK--DLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQqglln 2748
Cdd:COG3206    181 EEQLPELRKELEEAEAALEEFRQKNGlvDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA----- 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2749 rerhallsettfsmdLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDhlwnelekfrks 2828
Cdd:COG3206    256 ---------------LPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQ------------ 308

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 2829 eegkqrsaaqpatslaevQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQ 2895
Cdd:COG3206    309 ------------------QEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1983-2194 2.12e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1983 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAAR 2062
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2063 VLADNLKLKKELQS-------NKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTL 2135
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909132 2136 NKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEE 2194
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2254-2631 2.33e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 2.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2254 ENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFS--YEQLETD 2331
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPerLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2332 LQASREL---TSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDkEIKELENLLSQEEEENIVLEEENKKAVDKTN 2408
Cdd:COG4717    155 LEELRELeeeLEELEAELAELQEELEELLEQLSLATEEELQDLAEELE-ELQQRLAELEEELEEAQEELEELEEELEQLE 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2409 QLMETLNAIKKEN---------------IQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAE 2473
Cdd:COG4717    234 NELEAAALEERLKearlllliaaallalLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2474 NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKElknkyakleEKLKESEEANE 2553
Cdd:COG4717    314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA---------ALLAEAGVEDE 384

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909132 2554 DLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEEL 2631
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAEL 462
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2362-2589 2.37e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2362 EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKaVDKTNQLMETLNAIKKENIQQKAQLDsfvKSMSSLQND 2441
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR-IRALEQELAALEAELAELEKEIAELR---AELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2442 RDRIVGDYQQLEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdaeliqyrEDLNQVISIKDSQQK 2521
Cdd:COG4942    106 LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909132 2522 QLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTA 2589
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 944-1594 2.54e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.67  E-value: 2.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  944 EELQHEFDLLKKENEQRKRklqaalinrkellqrvsrLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSK 1023
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLES------------------AELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQ 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1024 CQEIEISLKQTISEKEVELEHIRKDLEekmAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTT------- 1096
Cdd:pfam12128  299 WKEKRDELNGELSAADAAVAKDRSELE---ALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGkhqdvta 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1097 ------SNTDASDGDSVALVKETVVISPPGTDSG------------EHWKPELEEKILALEKEKEQLQKKLQEAltsrKA 1158
Cdd:pfam12128  376 kynrrrSKIKEQNNRDIAGIKDKLAKIREARDRQlavaeddlqaleSELREQLEAGKLEFNEEEYRLKSRLGEL----KL 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1159 ILKKAQEKErHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQiQVRESIDGKLPSPDQ--QEWCSPTPGLEEPL 1236
Cdd:pfam12128  452 RLNQATATP-ELLLQLENFDERIERAREEQEAANAEVERLQSELRQAR-KRRDQASEALRQASRrlEERQSALDELELQL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1237 FKateQHHTQPVLESNLCPDWPSH-----------------SEDASALQGGTSVAQIKAQLK------------EIETEK 1287
Cdd:pfam12128  530 FP---QAGTLLHFLRKEAPDWEQSigkvispellhrtdldpEVWDGSVGGELNLYGVKLDLKridvpewaaseeELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1288 EKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESL--QQKLESSQLQIAGLEHLRELQPELDE 1365
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLfdEKQSEKDKKNKALAERKDSANERLNS 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1366 L---QKLISEKEEDVS-YLSGQLRE----KEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERI-KQLQVELCEMKQK 1436
Cdd:pfam12128  687 LeaqLKQLDKKHQAWLeEQKEQKREarteKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALeTWYKRDLASLGVD 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1437 PEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDtieHLTKSLADVESHVSaqnkekdRVLGRLALLQEE 1516
Cdd:pfam12128  767 PDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRP---RLATQLSNIERAIS-------ELQQQLARLIAD 836

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1517 ----RDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKL-VKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSY 1591
Cdd:pfam12128  837 tklrRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDAnSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHF 916


                   ...
gi 1622909132 1592 ENV 1594
Cdd:pfam12128  917 KNV 919
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2703-2910 2.79e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2703 QSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLnrerhallsettfsmDLPEENSLsylekLNQQLLS 2782
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLV---------------DLSEEAKL-----LLQQLSE 223

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2783 KDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWN--ELEKFRKSEEGKQRSAAQPATSLAE----VQSLKKAMSSL 2856
Cdd:COG3206    224 LESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARYTPnhpdVIALRAQIAAL 303

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909132 2857 QNDRDRLLKE-LKNLQQQYLQINQEITELRplkAQLQEYQDKTKTFQIMQEELRQ 2910
Cdd:COG3206    304 RAQLQQEAQRiLASLEAELEALQAREASLQ---AQLAQLEARLAELPELEAELRR 355
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 651-1086 2.99e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 2.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  651 HQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSVVTE 730
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  731 LRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQL- 809
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLl 494

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  810 ----QNKESEVLEGAERVRHISSKVEELSQALS---------QKELEIAKMDQLLLEKKRDVETLQQTIEE-KDQQVTEI 875
Cdd:COG1196    495 llleAEADYEGFLEGVKAALLLAGLRGLAGAVAvligveaayEAALEAALAAALQNIVVEDDEVAAAAIEYlKAAKAGRA 574

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  876 SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspaGLISKEELQHEFDLLKK 955
Cdd:COG1196    575 TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA---ALRRAVTLAGRLREVTL 651

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  956 ENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKcvtsKCQEIEISLKQTI 1035
Cdd:COG1196    652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE----ERLEEELEEEALE 727

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622909132 1036 SEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISE 1086
Cdd:COG1196    728 EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2105-2299 3.00e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2105 KEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKF 2184
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2185 SDAI-------QTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESK---AQTEVQLQQKVCDTLQGE 2254
Cdd:COG4942    107 AELLralyrlgRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALraeLEAERAELEALLAELEEE 186

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1622909132 2255 NKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEK 2299
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
PRK09039 PRK09039
peptidoglycan -binding protein;
2662-2797 3.40e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.65  E-value: 3.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2662 IMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIqsfgrsmSSLQNSRDHANEELDELKRKYDASLKELAQLK 2741
Cdd:PRK09039    43 FLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSV-------ANLRASLSAAEAERSRLQALLAELAGAGAAAE 115

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132 2742 EQQGLLNRErhaLLSETTFSmdlpeENSLSYLEKLNQQLLSKDEQLLHLSSQLEDS 2797
Cdd:PRK09039   116 GRAGELAQE---LDSEKQVS-----ARALAQVELLNQQIAALRRQLAALEAALDAS 163
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1432-2158 3.58e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.29  E-value: 3.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1432 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLArdtieHLTKSLADVESHVSAQNKEKDRVLGRL- 1510
Cdd:pfam12128  215 KSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLS-----HLHFGYKSDETLIASRQEERQETSAELn 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1511 ALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKE-IESLKSSKIAESSeWQEKHKELQKEYEILLQ 1589
Cdd:pfam12128  290 QLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDAdIETAAADQEQLPS-WQSELENLEERLKALTG 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1590 SYENVSNEAERIQHVVeaVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKfakSKQQKILELEEENDRLR 1669
Cdd:pfam12128  369 KHQDVTAKYNRRRSKI--KEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELRE---QLEAGKLEFNEEEYRLK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1670 AEVHPAGG--TAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEK---DSLSEEvQDLKHQLES---NVSKQAN 1741
Cdd:pfam12128  444 SRLGELKLrlNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELrqaRKRRDQ-ASEALRQASrrlEERQSAL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1742 LEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPAC-SESVPSENSANPAVSEDVSS------HDEINNYLQQIDQL 1814
Cdd:pfam12128  523 DELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHrTDLDPEVWDGSVGGELNLYGvkldlkRIDVPEWAASEEEL 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1815 KERIAGLEEEKQKNKEFSQTLEnernallSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTklketaeEEKDDLEER 1894
Cdd:pfam12128  603 RERLDKAEEALQSAREKQAAAE-------EQLVQANGELEKASREETFARTALKNARLDLRRLF-------DEKQSEKDK 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1895 LMNQLAELNGSIGNYCQDVtDAQIKneLLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgAQKEPGNKS 1974
Cdd:pfam12128  669 KNKALAERKDSANERLNSL-EAQLK--QLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLK-AAIAARRSG 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1975 HAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD 2054
Cdd:pfam12128  745 AKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAIS 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2055 DTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER-RLEQAEEKHLKEKKNMQEkldaLRREKVHLEETIGEIQV 2133
Cdd:pfam12128  825 ELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGlRCEMSKLATLKEDANSEQ----AQGSIGERLAQLEDLKL 900

                          730       740
                   ....*....|....*....|....*
gi 1622909132 2134 TLNKKDKEIQQVQENLDSTVAQLAA 2158
Cdd:pfam12128  901 KRDYLSESVKKYVEHFKNVIADHSG 925
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1271-1464 3.76e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 3.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1271 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLES--SQL 1348
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEraRAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1349 QIAG------------------LEHLRELQPELDELQKLISEKEEDVsylsGQLREKEAALTKIQTEIIEQEDLIKALHT 1410
Cdd:COG3883     96 YRSGgsvsyldvllgsesfsdfLDRLSALSKIADADADLLEELKADK----AELEAKKAELEAKLAELEALKAELEAAKA 171

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622909132 1411 QLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEA 1464
Cdd:COG3883    172 ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1130-1206 3.80e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 3.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1130 ELEEKILALEKEKEQLQKKLQEALTSRKAILKK----AQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1205
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDelaeLEEELEALKARWEAEKELIEEIQELKEELEQRYGKIPELEKEL 494


                   .
gi 1622909132 1206 Q 1206
Cdd:COG0542    495 A 495
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2006-2175 3.80e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 42.29  E-value: 3.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2006 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2081
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2082 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2138
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1622909132 2139 DKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2175
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2713-2968 3.95e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 3.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2713 QNSRDHANEELDELKRKYDASLKELAQLKEQQgllnrerhallsettfsmdlpeenslsylEKLNQQLLSKDEQLLHLSS 2792
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEE-----------------------------KALLKQLAALERRIAALAR 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2793 QLEDSYNQVQSFSKAMASLQNERDHLWNELEKfRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRD-RLLKEL-KNL 2870
Cdd:COG4942     70 RIRALEQELAALEAELAELEKEIAELRAELEA-QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRlQYLKYLaPAR 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2871 QQQYLQINQEITELRPLKAQLQEYQDKtktfqimQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQ 2950
Cdd:COG4942    149 REQAEELRADLAELAALRAELEAERAE-------LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221

                          250
                   ....*....|....*...
gi 1622909132 2951 VSHLQNLIRELRSSSSQA 2968
Cdd:COG4942    222 AEELEALIARLEAEAAAA 239
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 654-1211 3.98e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 3.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  654 ELERLKSQILELELNFHKAQE---IYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV-VT 729
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEErlaKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKeFA 381

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  730 ELRAQVRQLEMNLAEAERQRrfdYESQTAHHNL------LTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 803
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREI---NELKRELDRLqeelqrLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  804 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVE-----------TLQQTIEEKDQQV 872
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEvlkasiqgvhgTVAQLGSVGERYA 538

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  873 TEISFSMTEKMVQLNEEKFSLGVE-IKTLKEQ---------LNLLSRAE-------------------------EAKKEQ 917
Cdd:TIGR02169  539 TAIEVAAGNRLNNVVVEDDAVAKEaIELLKRRkagratflpLNKMRDERrdlsilsedgvigfavdlvefdpkyEPAFKY 618

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  918 VEEDNEVVSGLKQNYDEMSPAGLISKEElqhefDLLKKENEQR--KRKLQAALINRKELLQRVSRLEEELANLKDQskKE 995
Cdd:TIGR02169  619 VFGDTLVVEDIEAARRLMGKYRMVTLEG-----ELFEKSGAMTggSRAPRGGILFSRSEPAELQRLRERLEGLKRE--LS 691

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  996 IPLSESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTN 1075
Cdd:TIGR02169  692 SLQSELRRIENRLDELSQELSD-------------ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1076 QIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPPGTDSGEHWKP---ELEEKILALEKEKEQLQKKLQE- 1151
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEArlrEIEQKLNRLTLEKEYLEKEIQEl 838

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909132 1152 -----ALTSRKAILKKAQE----KERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRE 1211
Cdd:TIGR02169  839 qeqriDLKEQIKSIEKEIEnlngKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE 907
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1420-1672 4.21e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 4.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1420 DERIKQLQ----VELCEMKQK--PEEIEEESRAkqqiQRKLQAALISRKEALKENKSLQEELSLAR-----DTIEHLTKS 1488
Cdd:PRK05771    19 DEVLEALHelgvVHIEDLKEElsNERLRKLRSL----LTKLSEALDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1489 LADVESHVSAQNKEKDRvlgrlalLQEERDKLITEMDR-SLLENQSLS----GSCESLKLALEGLTEDKEKLVKEIESLK 1563
Cdd:PRK05771    95 LEKIEKEIKELEEEISE-------LENEIKELEQEIERlEPWGNFDLDlsllLGFKYVSVFVGTVPEDKLEELKLESDVE 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1564 SSKIAESSEwqEK-------HKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELygklrsteankketekqlQEA 1636
Cdd:PRK05771   168 NVEYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL------------------EEI 227

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1622909132 1637 EKEMEEMKEKMRKFAKSKQQKILELEE--ENDRLRAEV 1672
Cdd:PRK05771   228 EKERESLLEELKELAKKYLEELLALYEylEIELERAEA 265
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1883-2114 4.39e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 4.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1883 TAEEEKDDLEERLMN----QLAELNGSIGNYcqdvtdaqiKNELLESEMKNLKKCVSELEEEKQqlvKEKTKVESEIRKE 1958
Cdd:PRK05771    13 TLKSYKDEVLEALHElgvvHIEDLKEELSNE---------RLRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1959 YLEKIQGAQKEPGNKShakELQELLKEKQQEVKQLQKDCIRYQEKISALE---------------RTVKA---------- 2013
Cdd:PRK05771    81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELENEIKELEQEIERLEpwgnfdldlslllgfKYVSVfvgtvpedkl 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2014 LEFVQTESQKDLEITKEN-------LAQAVEHRKKAQAELASFKVLLDDTQSE--AARVLADNLKLKKELQSNKESVKSQ 2084
Cdd:PRK05771   158 EELKLESDVENVEYISTDkgyvyvvVVVLKELSDEVEEELKKLGFERLELEEEgtPSELIREIKEELEEIEKERESLLEE 237

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1622909132 2085 MKQKDEDLERRLEQAEEK--HLKEKKNMQEKL 2114
Cdd:PRK05771   238 LKELAKKYLEELLALYEYleIELERAEALSKF 269
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1809-1962 4.84e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 4.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1809 QQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE------ 1882
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1883 ---TAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1959
Cdd:COG1579     97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                   ...
gi 1622909132 1960 LEK 1962
Cdd:COG1579    177 LAL 179
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1337-1566 5.00e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 5.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1337 ESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALtkIQTEIIEQEDLIKALHTQLEmqa 1416
Cdd:COG4913    238 ERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELE--- 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1417 kEHDERIKQLQVELCEMKQKPEEIeeESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHV 1496
Cdd:COG4913    313 -RLEARLDALREELDELEAQIRGN--GGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1497 SAQnkeKDRVLGRLALLQEERDKLITemdrsllenqslsgsceslklALEGLTEDKEKLVKEIESLKSSK 1566
Cdd:COG4913    390 AAL---LEALEEELEALEEALAEAEA---------------------ALRDLRRELRELEAEIASLERRK 435
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2286-3152 5.13e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.73  E-value: 5.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2286 LKDQLTDLSNSLEKCKE---QKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKEE 2362
Cdd:TIGR00606  222 IRDQITSKEAQLESSREivkSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2363 AIQvaiaELRQQHDKEIKELENLLSQEeeenivleeenKKAVDKTNQLMETLNAIKKENIQQKAQLdsfvksmsSLQNDR 2442
Cdd:TIGR00606  302 QLN----DLYHNHQRTVREKERELVDC-----------QRELEKLNKERRLLNQEKTELLVEQGRL--------QLQADR 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2443 DRIVGDYQQLEERHLSVILEKDQLIQEAAAENnKLKEEIRGLRSHMDDLNSENAKLDAELiQYREDLNQVISIKDSQQKQ 2522
Cdd:TIGR00606  359 HQEHIRARDSLIQSLATRLELDGFERGPFSER-QIKNFHTLVIERQEDEAKTAAQLCADL-QSKERLKQEQADEIRDEKK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2523 LLEAQLQQNKEL----KNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESlkVSVSQLTRQVTALQEEG---- 2594
Cdd:TIGR00606  437 GLGRTIELKKEIlekkQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKN--SLTETLKKEVKSLQNEKadld 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2595 -TLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIED-KLKKELKHLHHDagiMRNETETAEE 2672
Cdd:TIGR00606  515 rKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfPNKKQLEDWLHS---KSKEINQTRD 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2673 RVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHaNEELDELKRKYDASLKELAQLKEQQGLLNRERH 2752
Cdd:TIGR00606  592 RLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE-ESDLERLKEEIEKSSKQRAMLAGATAVYSQFIT 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2753 ALLSETTFSMDL------PEENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR 2826
Cdd:TIGR00606  671 QLTDENQSCCPVcqrvfqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELR 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2827 KSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEyQDKTKTFQimqe 2906
Cdd:TIGR00606  751 NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQG-SDLDRTVQ---- 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2907 ELRQENLSWQHELhqlrmEKSSWEIHERRMkeqylmAISDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQAspetsas 2986
Cdd:TIGR00606  826 QVNQEKQEKQHEL-----DTVVSKIELNRK------LIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFE------- 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2987 pDGSQNLIYETELLRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQhygDLLNHCAVLEKQ 3066
Cdd:TIGR00606  888 -EQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVK---NIHGYMKDIENK 963

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 3067 VQELQAVSKEKGPLNIDVApGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLC-----NTRQEVNELRKLLEEERDQRVA 3141
Cdd:TIGR00606  964 IQDGKDDYLKQKETELNTV-NAQLEECEKHQEKINEDMRLMRQDIDTQKIQERwlqdnLTLRKRENELKEVEEELKQHLK 1042

                          890
                   ....*....|.
gi 1622909132 3142 AENALSLAEEQ 3152
Cdd:TIGR00606 1043 EMGQMQVLQMK 1053
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1273-1523 5.13e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 5.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1273 VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAG 1352
Cdd:COG4372     47 LEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQD 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1353 LEHLR-ELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIieQEDLIKALHTQLEMQAKEHDERIKQLQVELC 1431
Cdd:COG4372    127 LEQQRkQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL--QALSEAEAEQALDELLKEANRNAEKEEELAE 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1432 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLA 1511
Cdd:COG4372    205 AEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALE 284

                          250
                   ....*....|..
gi 1622909132 1512 LLQEERDKLITE 1523
Cdd:COG4372    285 LEALEEAALELK 296
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1284-1481 5.45e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 5.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1284 ETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAglehlrELQPEL 1363
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIE------ERREEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1364 DELQKLISEKEEDVSYLS-----------------------------GQLREKEAALTKIQTEIIEQEDLIKALHTQLEM 1414
Cdd:COG3883     89 GERARALYRSGGSVSYLDvllgsesfsdfldrlsalskiadadadllEELKADKAELEAKKAELEAKLAELEALKAELEA 168

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909132 1415 QAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDT 1481
Cdd:COG3883    169 AKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 2132-2536 6.55e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.35  E-value: 6.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2132 QVTLNKKDKEIQQVQEnLDSTVAQLAAFTKSMSSLQDDRdRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVlkDQLRQ 2211
Cdd:PRK10929    34 QAKAAKTPAQAEIVEA-LQSALNWLEERKGSLERAKQYQ-QVIDNFPKLSAELRQQLNNERDEPRSVPPNMST--DALEQ 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2212 msihmEELKINISRLEHDKQiweskAQTEVQLQQKVCDTL------QGENKELLSQLEETRHLYHN-----SQNELAKLE 2280
Cdd:PRK10929   110 -----EILQVSSQLLEKSRQ-----AQQEQDRAREISDSLsqlpqqQTEARRQLNEIERRLQTLGTpntplAQAQLTALQ 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2281 SELNILKDQLtdlsNSLEKCKEQKENLEGIIRQQeadIQNSKFSYEQLETDLQAsreltsrLHEEINMKEQKMISLLSGK 2360
Cdd:PRK10929   180 AESAALKALV----DELELAQLSANNRQELARLR---SELAKKRSQQLDAYLQA-------LRNQLNSQRQREAERALES 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2361 EEAIQVAIAELRQQHDKEIK---ELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKkeniQQKAQLDSfvksmss 2437
Cdd:PRK10929   246 TELLAEQSGDLPKSIVAQFKinrELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTLR----EQSQWLGV------- 314

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2438 lqndrDRIVGDYQQLEERHLSVILEKDQLIQEAAaennklkeEIRGLRSHMDDLNSENAKLDaeliQYREDLNQVISikd 2517
Cdd:PRK10929   315 -----SNALGEALRAQVARLPEMPKPQQLDTEMA--------QLRVQRLRYEDLLNKQPQLR----QIRQADGQPLT--- 374

                          410
                   ....*....|....*....
gi 1622909132 2518 SQQKQLLEAQLQQNKELKN 2536
Cdd:PRK10929   375 AEQNRILDAQLRTQRELLN 393
mukB PRK04863
chromosome partition protein MukB;
2668-2970 6.83e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 6.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2668 ETAEERVAELARDLVEMEQKllmvtkenkdlTAQIQSFGRSMSSLQ---NSRDHANEELDELKRKYDASLKELAQLKEQQ 2744
Cdd:PRK04863   890 ETLADRVEEIREQLDEAEEA-----------KRFVQQHGNALAQLEpivSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQA 958

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2745 GLLN--RERHALLSETTFSMDLPEENSLSylEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNEL 2822
Cdd:PRK04863   959 FALTevVQRRAHFSYEDAAEMLAKNSDLN--EKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQML 1036

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2823 ekfrksEEGKQRSAAQ--PATSLAEVQslkkamssLQNDRDRLLKELKNLQQQYLQINQEIT----ELRPLKAQLQEYQd 2896
Cdd:PRK04863  1037 ------QELKQELQDLgvPADSGAEER--------ARARRDELHARLSANRSRRNQLEKQLTfceaEMDNLTKKLRKLE- 1101

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2897 ktKTFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERR---MKEQYLMAISDKDQ-----QVSHLQNLIRELRSSSSQA 2968
Cdd:PRK04863  1102 --RDYHEMREQVVNAKAGWCAVLRLVKDNGVERRLHRRElayLSADELRSMSDKALgalrlAVADNEHLRDVLRLSEDPK 1179


                   ..
gi 1622909132 2969 QP 2970
Cdd:PRK04863  1180 RP 1181
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 800-1014 6.93e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 6.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  800 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM 879
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  880 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagliskEELQHEFDLLKKENE 958
Cdd:COG3883     96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAEL--------EAKLAELEALKAELE 167

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132  959 QRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKE 1014
Cdd:COG3883    168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2469-2938 7.35e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 7.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2469 EAAAEN-NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQL--LEAQLQQNKELKNKYAKLEEKL 2545
Cdd:PRK03918   161 ENAYKNlGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELpeLREELEKLEKEVKELEELKEEI 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2546 KESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQE-----------EGTLGIYHAQLKVKEEELQRLS 2614
Cdd:PRK03918   241 EELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKElkekaeeyiklSEFYEEYLDELREIEKRLSRLE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2615 ALLSSSQKRITELE------EELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKL 2688
Cdd:PRK03918   321 EEINGIEERIKELEekeerlEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2689 LMVTKENKDLTAQIQSFGRSMSSLQNS---------------RDHANEELDELKRKYDASLKELAqlKEQQGLLNRERHA 2753
Cdd:PRK03918   401 EEIEEEISKITARIGELKKEIKELKKAieelkkakgkcpvcgRELTEEHRKELLEEYTAELKRIE--KELKEIEEKERKL 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2754 LLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQL-LHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFrksEEGK 2832
Cdd:PRK03918   479 RKELRELEKVLKKESELIKLKELAEQLKELEEKLkKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL---EELK 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2833 QRSAAqpatslaevqsLKKAMSSLQNDRDRLLKELKNLQQQYL-QINQEITELRPLKAQLQEYQDKTKTFQIMQEELRQE 2911
Cdd:PRK03918   556 KKLAE-----------LEKKLDELEEELAELLKELEELGFESVeELEERLKELEPFYNEYLELKDAEKELEREEKELKKL 624

                          490       500
                   ....*....|....*....|....*..
gi 1622909132 2912 NLSWQHELHQLRMEKSSWEIHERRMKE 2938
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEE 651
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2440-2726 7.37e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 7.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2440 NDRDRIVGDY-------QQLEErhlsvileKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdAELIQYREDLNQV 2512
Cdd:COG4913    593 DDRRRIRSRYvlgfdnrAKLAA--------LEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV 663

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2513 isikDSQQKQL--LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTAL 2590
Cdd:COG4913    664 ----ASAEREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 2591 QEEGTLGiYHAQLkvkeeELQRLSALLSSSQKRITE-LEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETET 2669
Cdd:COG4913    740 EDLARLE-LRALL-----EERFAAALGDAVERELREnLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLES 813

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622909132 2670 AEERVAELAR----DLVEMEQKLL-MVTKENKDLTAQIQsfgrsmSSLQNSRDHANEELDEL 2726
Cdd:COG4913    814 LPEYLALLDRleedGLPEYEERFKeLLNENSIEFVADLL------SKLRRAIREIKERIDPL 869
46 PHA02562
endonuclease subunit; Provisional
 629-870 8.15e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 8.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  629 ELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILElelNFHKAQEIYEKNLdEKAK----EISNLNQLIEEFKKNADNN 704
Cdd:PHA02562   178 ELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGE---NIARKQNKYDELV-EEAKtikaEIEELTDELLNLVMDIEDP 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  705 SSAFTALSEERDQLLAQVKELSVVTELraqvrqlemnlaeaerqrrfdYESQ----TAHHNLLTEQIHSLSIEAKSKDV- 779
Cdd:PHA02562   254 SAALNKLNTAAAKIKSKIEQFQKVIKM---------------------YEKGgvcpTCTQQISEGPDRITKIKDKLKELq 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  780 ----KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQlllEKK 855
Cdd:PHA02562   313 hsleKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD---ELD 389

                          250
                   ....*....|....*
gi 1622909132  856 RDVETLQQTIEEKDQ 870
Cdd:PHA02562   390 KIVKTKSELVKEKYH 404
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 1277-1583 8.38e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 41.76  E-value: 8.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1277 KAQLKEIETEKEKLELKISSTTSELTKKSEEVfqLQDQINKQGLEIESLKTASheaeVRAESLQQKLESSQLQIAGL--- 1353
Cdd:PLN03229   428 KTPVRELEGEVEKLKEQILKAKESSSKPSELA--LNEMIEKLKKEIDLEYTEA----VIAMGLQERLENLREEFSKAnsq 501

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1354 EHLreLQPEL-DELQKLISEKEEDVS----YLSgqLREKEAALTKIQTEIIEQEDLIKALHTQLEMqakehDERIKQLqV 1428
Cdd:PLN03229   502 DQL--MHPVLmEKIEKLKDEFNKRLSrapnYLS--LKYKLDMLNEFSRAKALSEKKSKAEKLKAEI-----NKKFKEV-M 571

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1429 ELCEMKQKPEEIEEESrAKQQIQRKLQAALISRKEALKENKSLQEEL-----SLARDTIEHLTKSLADVESHVSAQNKEK 1503
Cdd:PLN03229   572 DRPEIKEKMEALKAEV-ASSGASSGDELDDDLKEKVEKMKKEIELELagvlkSMGLEVIGVTKKNKDTAEQTPPPNLQEK 650

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1504 drvlgrLALLQEERDKLITEMDRSllenQSLSGSCESLKL--ALEGLTEDKEkLVKEIESLKSS---KIAE---SSEWQE 1575
Cdd:PLN03229   651 ------IESLNEEINKKIERVIRS----SDLKSKIELLKLevAKASKTPDVT-EKEKIEALEQQikqKIAEalnSSELKE 719


                   ....*...
gi 1622909132 1576 KHKELQKE 1583
Cdd:PLN03229   720 KFEELEAE 727
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 220-1053 9.01e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.88  E-value: 9.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  220 QQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAE 299
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  300 RKLSFHNLQEEMRHLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKD 379
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  380 EQAVQSAQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQTCFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLS 459
Cdd:pfam02463  336 EIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  460 SIELEELKAENEKLSSQITLLEAQNRIGEADREVSEISIVDDAnkrsssTEESGQDVLENTFSQKHKELSVLLLEMKEAQ 539
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQEL------KLLKDELELKKSEDLLKETQLVKLQEQLELL 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  540 EEIAFLK--LQLQGKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDTGQNFPLMPNEESSLPAVEKEQASTEHQNRT 617
Cdd:pfam02463  490 LSRQKLEerSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRA 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  618 SEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEF 697
Cdd:pfam02463  570 LTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLR 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  698 KKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLSIEAKS- 776
Cdd:pfam02463  650 KGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQe 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  777 KDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKR 856
Cdd:pfam02463  730 AQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEE 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  857 DVETLQQT------------IEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEV 924
Cdd:pfam02463  810 LKEEAELLeeeqllieqeekIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELE 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  925 VSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE-LANLKDQSKKEIPLSESER 1003
Cdd:pfam02463  890 SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEkEENNKEEEEERNKRLLLAK 969

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1004 GEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKM 1053
Cdd:pfam02463  970 EELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRL 1019
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1275-1636 9.22e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.93  E-value: 9.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1275 QIKAQLKEIETE-----KEKLELKISSTTSELTKKSEEVFQLQDQ-------INKQGLEIESLKTASHEAEVRAESLQQK 1342
Cdd:TIGR04523  285 ELEKQLNQLKSEisdlnNQKEQDWNKELKSELKNQEKKLEEIQNQisqnnkiISQLNEQISQLKKELTNSESENSEKQRE 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1343 LESSQLQIAGLEhlRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQT------EIIEQEDLIKALHTQLEMQA 1416
Cdd:TIGR04523  365 LEEKQNEIEKLK--KENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKlqqekeLLEKEIERLKETIIKNNSEI 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1417 KEHDERIKQLQVELCEMKQKPEEIEEE----SRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADV 1492
Cdd:TIGR04523  443 KDLTNQDSVKELIIKNLDNTRESLETQlkvlSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSL 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132 1493 ESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKL-----ALEGLTEDKEKLVKEIESLKSSKI 1567
Cdd:TIGR04523  523 KEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELkqtqkSLKKKQEEKQELIDQKEKEKKDLI 602

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909132 1568 AESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1636
Cdd:TIGR04523  603 KEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKES 671
PLN02939 PLN02939
transferase, transferring glycosyl groups
 595-962 9.33e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 41.81  E-value: 9.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  595 PNEESSLPAVEKEQASTEHQNRTSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDeleRLKSQILELelNFHKAQE 674
Cdd:PLN02939    40 RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHN---RASMQRDEA--IAAIDNE 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  675 IYEKNLDEKakEISNLNqlIEEFKKNADNNSSAFTALSEERDQLLAQV-KELSVVTELRAQVRQLEMNLAEAERQRRFDY 753
Cdd:PLN02939   115 QQTNSKDGE--QLSDFQ--LEDLVGMIQNAEKNILLLNQARLQALEDLeKILTEKEALQGKINILEMRLSETDARIKLAA 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  754 ESQtAHHNLLTEQI----HSLSIEAKSKDVKIEVLQNELDDVQlqfsEQSTLIRSLQSQLQNKESEVLEGAERV------ 823
Cdd:PLN02939   191 QEK-IHVEILEEQLeklrNELLIRGATEGLCVHSLSKELDVLK----EENMLLKDDIQFLKAELIEVAETEERVfkleke 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  824 -RHISSKVEELSQALSQKELEIAKMDQLLLEKKRD-VETLQQTIEEKDQQVTEISFSMT-----EKMVQLNEEKFSLGVE 896
Cdd:PLN02939   266 rSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEkVENLQDLLDRATNQVEKAALVLDqnqdlRDKVDKLEASLKEANV 345

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909132  897 IKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEmspagliSKEELQHEFDLLKKENEQRKR 962
Cdd:PLN02939   346 SKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQE-------SIKEFQDTLSKLKEESKKRSL 404
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
463-990 9.96e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.56  E-value: 9.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  463 LEELKAENEKLSSQiTLLEAQNRIGEADREV-SEISIVDDANKRSSSTEESGQDVLEnTFSQKHKELSVLLLEMKEAQEE 541
Cdd:PRK02224   189 LDQLKAQIEEKEEK-DLHERLNGLESELAELdEEIERYEEQREQARETRDEADEVLE-EHEERREELETLEAEIEDLRET 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  542 IAFLKlqlqgKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDtgqnfplmpneeSSLPAVEKEQASTEHQNRTSEEi 621
Cdd:PRK02224   267 IAETE-----REREELAEEVRDLRERLEELEEERDDLLAEAGLDD------------ADAEAVEARREELEDRDEELRD- 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  622 SLNDAGVELKSTKQDCDKSLSAVPDigqcHQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNA 701
Cdd:PRK02224   329 RLEECRVAAQAHNEEAESLREDADD----LEERAEELREEAAELESELEEARE----AVEDRREEIEELEEEIEELRERF 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  702 DNNSSAFTALSEERDQLLAQVKEL-SVVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHnlLTEQIHSLSIEakSKDVK 780
Cdd:PRK02224   401 GDAPVDLGNAEDFLEELREERDELrEREAELEATLRTARERVEEAEALLEAGKCPECGQP--VEGSPHVETIE--EDRER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  781 IEVLQNELDDVQLQFS------EQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEK 854
Cdd:PRK02224   477 VEELEAELEDLEEEVEeveerlERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909132  855 KRDVETLQQTIEEKDQQVTEISFSMTE---------KMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVV 925
Cdd:PRK02224   557 REAAAEAEEEAEEAREEVAELNSKLAElkeriesleRIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERK 636

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909132  926 SGLKQNYDEMspagliSKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKD 990
Cdd:PRK02224   637 RELEAEFDEA------RIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEE 695
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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