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Conserved domains on  [gi|1622909128|ref|XP_014985469|]
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golgin subfamily B member 1 isoform X4 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1903-2775 1.85e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 1.85e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1903 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1972
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1973 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2045
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2046 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD---------DTQSEAARVLADNLK------------LK 2104
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEeleaeleelESRLEELEEQLETLRskvaqlelqiasLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2105 KELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2184
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2185 TVAQLAAFTKSMSSLQDDRDRV------IDEAKKWERKFSDAIQTKEEEIRLKE--ENCSVLKDQLRQMSIHMEELKINI 2256
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLegfsegVKALLKNQSGLSGILGVLSELISVDEgyEAAIEAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2257 SRLEHDKQIWESKAqTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQL---TDLSNSLEKC 2333
Cdd:TIGR02168  560 KAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2334 KeqKENLEGIIRQQEADIQNSKFSYEQletdlQASRELTSRLHEEINMKE-QKMISLLSGKEEAIQVAIAELRQQHDkei 2412
Cdd:TIGR02168  639 K--KLRPGYRIVTLDGDLVRPGGVITG-----GSAKTNSSILERRREIEElEEKIEELEEKIAELEKALAELRKELE--- 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2413 kELENLLSQEeeenivleeenkkavdktnqlmetlnaikkeniqqKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsv 2492
Cdd:TIGR02168  709 -ELEEELEQL-----------------------------------RKELEELSRQISALRKDLARLEAEVEQLEER---- 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2493 ILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleaqlqqnKELKNKYA 2572
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAA 820

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2573 KLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyhaqLKVKEEELQRLSALLSS 2652
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALAL 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2653 SQKRITELEEELvcvqKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKEN 2728
Cdd:TIGR02168  892 LRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDE 967

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909128 2729 KDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2775
Cdd:TIGR02168  968 EEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1304-2089 4.13e-19

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 95.52  E-value: 4.13e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1304 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGL-EIESLKTASHEAEVRAESLQQKLESSQLQ 1382
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1383 iaglehLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1459
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1460 QVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARDTIEHLTKSLADVESH 1528
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1529 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEG-------LTEDKEKLVKEIESLKSSKIA 1601
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqLGSVGERYATAIEVAAGNRLN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1602 ----ESSEWQEKHKELQKEYEILLQSYENVsNEAERIQHVVEAVRQEKQELYGklrsteANKKETEKQLQEAEKEMEEMK 1677
Cdd:TIGR02169  551 nvvvEDDAVAKEAIELLKRRKAGRATFLPL-NKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1678 EKMRKFAKSKQQ--KILELEEENDRLRAEVHPAGGTAKECMETLLSsnASMKEEVERVKMEYETLSKKFQSLMSEKDSLS 1755
Cdd:TIGR02169  624 LVVEDIEAARRLmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFS--RSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1756 EEVQDLKHQLESnvsKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSlsmstrpacsesvpsensanpavsedvSSHD 1835
Cdd:TIGR02169  702 NRLDELSQELSD---ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS---------------------------SLEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1836 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAllSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE 1915
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1916 TAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1995
Cdd:TIGR02169  830 YLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1996 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR-------------YQEKISALERTVKALEFVQTESQKDLEITK 2062
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelsledVQAELQRVEEEIRALEPVNMLAIQEYEEVL 985

                          810       820
                   ....*....|....*....|....*..
gi 1622909128 2063 ENLAQAVEHRKKAQAELASFKVLLDDT 2089
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 760-1648 2.27e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.27e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  760 VVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLsieakskdvkievlQNELDDVQLQFSEQSTLIRSLQ 839
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL--------------REELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  840 SQLQNKESEvlegaervrhisskveelsqaLSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQL 919
Cdd:TIGR02168  260 AELQELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  920 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAglisKEELQHEFDLLKKENEQRKRKLQA 999
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1000 ALINRKELLQRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIR 1079
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1080 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASdgdsvALVKETVVISPPGTDSGEH 1159
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK-----ALLKNQSGLSGILGVLSEL 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1160 WKPElEEKILALEKekeQLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIG 1232
Cdd:TIGR02168  529 ISVD-EGYEAAIEA---ALGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1233 DQLRQLQIQVRESIDGKLPSpdqqewCSPTPGLEEplfkATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQ 1308
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLGG------VLVVDDLDN----ALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILE 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1309 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEH 1388
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1389 lrelqpELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHderiKQLQVELCEMKQ 1468
Cdd:TIGR02168  755 ------ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL----TLLNEEAANLRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1469 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEhltkslADVESHVsaqnKEKDRVLGRLALLQE 1548
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE------SELEALL----NERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1549 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEssewqekhkELQKEYEILLQSYENVS 1628
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIE 964

                          890       900
                   ....*....|....*....|
gi 1622909128 1629 NEAERIQHVVEAVRQEKQEL 1648
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 215-1035 1.83e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.83e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  215 EQAAQVVREKDARFETQVRLHE-DELLQLVTqaDVETEMQQKLRVLQRK---------LEEHEESLVGRAQVVDLlqQEL 284
Cdd:TIGR02168  162 EEAAGISKYKERRKETERKLERtRENLDRLE--DILNELERQLKSLERQaekaerykeLKAELRELELALLVLRL--EEL 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  285 TAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQAELESR 364
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  365 YSALE---QKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKllqdKDEQAVQSAQTIEQLEDQLQQKSKEISQFLN 441
Cdd:TIGR02168  318 LEELEaqlEELESKLDELAEELAELEEKLEELKEELESLEAELEE----LEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  442 RLPLQQHETasqtcfpdVYNEGTQAVTEENIASLQKRVVELENE--KGALLLSSIELEELKAENEKLSSQitLLEAQNRI 519
Cdd:TIGR02168  394 QIASLNNEI--------ERLEARLERLEDRRERLQQEIEELLKKleEAELKELQAELEELEEELEELQEE--LERLEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  520 GEADREVSEISIVDDANKRSSSTEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEGDH---EVLD 596
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEaaiEAAL 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  597 QKEMKQMEGEGIAPIKMEV-FLEDTGQ---NFPLMPNEESSLPAVEKEQASTEHQNRTSEEISLNDAGVELKSTKQDCDK 672
Cdd:TIGR02168  544 GGRLQAVVVENLNAAKKAIaFLKQNELgrvTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLG 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  673 SLSAVPDIgqchqDELERLKSQILELELNFHKAQEIY-------------EKNLDEKAKEISNLNQLIEEFKKNADNNSS 739
Cdd:TIGR02168  624 GVLVVDDL-----DNALELAKKLRPGYRIVTLDGDLVrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  740 AFTALSEERDQLLAQVKEL-SVVTELRAQVRQLEMNLAEAERQrrfdyesqtahHNLLTEQIHSLSIEAKSKDVKIEVLQ 818
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLrKELEELSRQISALRKDLARLEAE-----------VEQLEERIAQLSKELTELEAEIEELE 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  819 NELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTI 898
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  899 EEKDQQVTEISFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSpagliskeE 978
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEELSEELRELESKRS--------E 912

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128  979 LQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESE 1035
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2447-3190 1.20e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 1.20e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2447 LNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSV---ILEKDQLIQEAAAENNKLKEEIRGLRSHMDD 2523
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELeeeIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2524 LNSENAKLDAELIQYREDLNQVISIKDSQQKQL------LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQE 2597
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2598 EKRDLSKEIESLKVSVSQLTRQVTALQEE-----------------GTLGIYHAQLKVKEEELQRLSALLSSSQKRITEL 2660
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2661 EEELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMV 2724
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2725 TKENKDLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSM 2795
Cdd:TIGR02168  554 NLNAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2796 DLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpats 2875
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEEL----------------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2876 LAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQL 2955
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2956 RMEKSSWEIHERRMKEQYLMAisDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRN 3035
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 3036 QLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNI 3115
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRR 915

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128 3116 DvapgapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSLAEEQIRRLE 3190
Cdd:TIGR02168  916 E-------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1903-2775 1.85e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 1.85e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1903 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1972
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1973 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2045
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2046 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD---------DTQSEAARVLADNLK------------LK 2104
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEeleaeleelESRLEELEEQLETLRskvaqlelqiasLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2105 KELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2184
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2185 TVAQLAAFTKSMSSLQDDRDRV------IDEAKKWERKFSDAIQTKEEEIRLKE--ENCSVLKDQLRQMSIHMEELKINI 2256
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLegfsegVKALLKNQSGLSGILGVLSELISVDEgyEAAIEAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2257 SRLEHDKQIWESKAqTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQL---TDLSNSLEKC 2333
Cdd:TIGR02168  560 KAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2334 KeqKENLEGIIRQQEADIQNSKFSYEQletdlQASRELTSRLHEEINMKE-QKMISLLSGKEEAIQVAIAELRQQHDkei 2412
Cdd:TIGR02168  639 K--KLRPGYRIVTLDGDLVRPGGVITG-----GSAKTNSSILERRREIEElEEKIEELEEKIAELEKALAELRKELE--- 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2413 kELENLLSQEeeenivleeenkkavdktnqlmetlnaikkeniqqKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsv 2492
Cdd:TIGR02168  709 -ELEEELEQL-----------------------------------RKELEELSRQISALRKDLARLEAEVEQLEER---- 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2493 ILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleaqlqqnKELKNKYA 2572
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAA 820

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2573 KLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyhaqLKVKEEELQRLSALLSS 2652
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALAL 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2653 SQKRITELEEELvcvqKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKEN 2728
Cdd:TIGR02168  892 LRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDE 967

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909128 2729 KDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2775
Cdd:TIGR02168  968 EEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1304-2089 4.13e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.52  E-value: 4.13e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1304 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGL-EIESLKTASHEAEVRAESLQQKLESSQLQ 1382
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1383 iaglehLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1459
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1460 QVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARDTIEHLTKSLADVESH 1528
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1529 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEG-------LTEDKEKLVKEIESLKSSKIA 1601
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqLGSVGERYATAIEVAAGNRLN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1602 ----ESSEWQEKHKELQKEYEILLQSYENVsNEAERIQHVVEAVRQEKQELYGklrsteANKKETEKQLQEAEKEMEEMK 1677
Cdd:TIGR02169  551 nvvvEDDAVAKEAIELLKRRKAGRATFLPL-NKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1678 EKMRKFAKSKQQ--KILELEEENDRLRAEVHPAGGTAKECMETLLSsnASMKEEVERVKMEYETLSKKFQSLMSEKDSLS 1755
Cdd:TIGR02169  624 LVVEDIEAARRLmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFS--RSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1756 EEVQDLKHQLESnvsKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSlsmstrpacsesvpsensanpavsedvSSHD 1835
Cdd:TIGR02169  702 NRLDELSQELSD---ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS---------------------------SLEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1836 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAllSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE 1915
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1916 TAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1995
Cdd:TIGR02169  830 YLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1996 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR-------------YQEKISALERTVKALEFVQTESQKDLEITK 2062
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelsledVQAELQRVEEEIRALEPVNMLAIQEYEEVL 985

                          810       820
                   ....*....|....*....|....*..
gi 1622909128 2063 ENLAQAVEHRKKAQAELASFKVLLDDT 2089
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 760-1648 2.27e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.27e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  760 VVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLsieakskdvkievlQNELDDVQLQFSEQSTLIRSLQ 839
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL--------------REELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  840 SQLQNKESEvlegaervrhisskveelsqaLSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQL 919
Cdd:TIGR02168  260 AELQELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  920 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAglisKEELQHEFDLLKKENEQRKRKLQA 999
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1000 ALINRKELLQRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIR 1079
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1080 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASdgdsvALVKETVVISPPGTDSGEH 1159
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK-----ALLKNQSGLSGILGVLSEL 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1160 WKPElEEKILALEKekeQLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIG 1232
Cdd:TIGR02168  529 ISVD-EGYEAAIEA---ALGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1233 DQLRQLQIQVRESIDGKLPSpdqqewCSPTPGLEEplfkATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQ 1308
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLGG------VLVVDDLDN----ALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILE 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1309 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEH 1388
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1389 lrelqpELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHderiKQLQVELCEMKQ 1468
Cdd:TIGR02168  755 ------ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL----TLLNEEAANLRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1469 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEhltkslADVESHVsaqnKEKDRVLGRLALLQE 1548
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE------SELEALL----NERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1549 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEssewqekhkELQKEYEILLQSYENVS 1628
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIE 964

                          890       900
                   ....*....|....*....|
gi 1622909128 1629 NEAERIQHVVEAVRQEKQEL 1648
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1308-1855 4.22e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 4.22e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1308 QIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE 1387
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1388 H-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1466
Cdd:COG1196    316 ErLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1467 KQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALL 1546
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1547 QEERDKLitemDRSLLENQSLSGSCESLKLALEGLTED-KEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYE 1625
Cdd:COG1196    476 EAALAEL----LEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1626 NVSNEAERIqhvvEAVRQEKQELYGK-----LRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDR 1700
Cdd:COG1196    552 VVEDDEVAA----AAIEYLKAAKAGRatflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1701 LRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEK 1780
Cdd:COG1196    628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909128 1781 HDNQMNVTEEATQSIpgETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLE 1855
Cdd:COG1196    708 ELAEAEEERLEEELE--EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 215-1035 1.83e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.83e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  215 EQAAQVVREKDARFETQVRLHE-DELLQLVTqaDVETEMQQKLRVLQRK---------LEEHEESLVGRAQVVDLlqQEL 284
Cdd:TIGR02168  162 EEAAGISKYKERRKETERKLERtRENLDRLE--DILNELERQLKSLERQaekaerykeLKAELRELELALLVLRL--EEL 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  285 TAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQAELESR 364
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  365 YSALE---QKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKllqdKDEQAVQSAQTIEQLEDQLQQKSKEISQFLN 441
Cdd:TIGR02168  318 LEELEaqlEELESKLDELAEELAELEEKLEELKEELESLEAELEE----LEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  442 RLPLQQHETasqtcfpdVYNEGTQAVTEENIASLQKRVVELENE--KGALLLSSIELEELKAENEKLSSQitLLEAQNRI 519
Cdd:TIGR02168  394 QIASLNNEI--------ERLEARLERLEDRRERLQQEIEELLKKleEAELKELQAELEELEEELEELQEE--LERLEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  520 GEADREVSEISIVDDANKRSSSTEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEGDH---EVLD 596
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEaaiEAAL 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  597 QKEMKQMEGEGIAPIKMEV-FLEDTGQ---NFPLMPNEESSLPAVEKEQASTEHQNRTSEEISLNDAGVELKSTKQDCDK 672
Cdd:TIGR02168  544 GGRLQAVVVENLNAAKKAIaFLKQNELgrvTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLG 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  673 SLSAVPDIgqchqDELERLKSQILELELNFHKAQEIY-------------EKNLDEKAKEISNLNQLIEEFKKNADNNSS 739
Cdd:TIGR02168  624 GVLVVDDL-----DNALELAKKLRPGYRIVTLDGDLVrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  740 AFTALSEERDQLLAQVKEL-SVVTELRAQVRQLEMNLAEAERQrrfdyesqtahHNLLTEQIHSLSIEAKSKDVKIEVLQ 818
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLrKELEELSRQISALRKDLARLEAE-----------VEQLEERIAQLSKELTELEAEIEELE 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  819 NELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTI 898
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  899 EEKDQQVTEISFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSpagliskeE 978
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEELSEELRELESKRS--------E 912

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128  979 LQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESE 1035
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1840-2366 5.11e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 5.11e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1840 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEE 1919
Cdd:COG1196    230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1920 EKDDLE---ERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKI 1996
Cdd:COG1196    310 RRRELEerlEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1997 QGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQ 2076
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2077 AELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALRR 2152
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2153 EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKE 2232
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2233 ENC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNS 2305
Cdd:COG1196    630 ARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909128 2306 QNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQ 2366
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 760-1105 8.83e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 8.83e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  760 VVTELRAQVRQLEmnlAEAERQRRFdyesqtahhNLLTEQIHSLSIEAKSKdvKIEVLQNELDDVQLQFSEQSTLIRSLQ 839
Cdd:COG1196    194 ILGELERQLEPLE---RQAEKAERY---------RELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  840 SQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQL 919
Cdd:COG1196    260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  920 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDemspagliskEELQHEFDLLKKENEQRKRKLQA 999
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE----------ELAEELLEALRAAAELAAQLEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1000 ALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSkcQEIEISLKQTISEKEVELEHIR 1079
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL--LELLAELLEEAALLEAALAELL 483

                          330       340
                   ....*....|....*....|....*.
gi 1622909128 1080 KDLEEKMAAEEQLQALVKEMNQTLQD 1105
Cdd:COG1196    484 EELAEAAARLLLLLEAEADYEGFLEG 509
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2447-3190 1.20e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 1.20e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2447 LNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSV---ILEKDQLIQEAAAENNKLKEEIRGLRSHMDD 2523
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELeeeIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2524 LNSENAKLDAELIQYREDLNQVISIKDSQQKQL------LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQE 2597
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2598 EKRDLSKEIESLKVSVSQLTRQVTALQEE-----------------GTLGIYHAQLKVKEEELQRLSALLSSSQKRITEL 2660
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2661 EEELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMV 2724
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2725 TKENKDLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSM 2795
Cdd:TIGR02168  554 NLNAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2796 DLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpats 2875
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEEL----------------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2876 LAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQL 2955
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2956 RMEKSSWEIHERRMKEQYLMAisDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRN 3035
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 3036 QLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNI 3115
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRR 915

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128 3116 DvapgapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSLAEEQIRRLE 3190
Cdd:TIGR02168  916 E-------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1497-2090 1.31e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.40  E-value: 1.31e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1497 ALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMD---RSLLENQSLSGSCES 1573
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1574 LKLALEGLTEDKEKL---VKEIESLKSSKIAESSEWQEKHKELQ------KEYEIL---LQSYENVSNEAERIQHVVEAV 1641
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLsefYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1642 RQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskqQKILELEEENDRLRAEVhpaGGTAKECMETLLS 1721
Cdd:PRK03918   323 INGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY-----EEAKAKKEELERLKKRL---TGLTPEKLEKELE 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1722 SNASMKEEVERvkmEYETLSKKFQSLMSEKDSLSEEVQDLKHQleSNVSKQANLEATEKHdnQMNVTEEATQSIPGETED 1801
Cdd:PRK03918   395 ELEKAKEEIEE---EISKITARIGELKKEIKELKKAIEELKKA--KGKCPVCGRELTEEH--RKELLEEYTAELKRIEKE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1802 QDSLSMSTRPACSESVPSENSANPavSEDVSSHDEInnyLQQIDQLKERIAG--LEEEKQKNKEFSQTLEnernallsQI 1879
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKK--ESELIKLKEL---AEQLKELEEKLKKynLEELEKKAEEYEKLKE--------KL 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1880 STKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLESE 1959
Cdd:PRK03918   535 IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYNE 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1960 MKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKIS 2038
Cdd:PRK03918   604 YLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSRELA 676

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622909128 2039 ALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2090
Cdd:PRK03918   677 GLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 687-1133 5.51e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 5.51e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  687 ELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKElsvvtelra 766
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHK--------- 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  767 qvRQLEMNLAEAERQRRFDYESQTAhhnllteqihslsieakskdVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKE 846
Cdd:pfam15921  389 --REKELSLEKEQNKRLWDRDTGNS--------------------ITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  847 SEVL-------EGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQL 919
Cdd:pfam15921  447 ERQMaaiqgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSR 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  920 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMS--------PAGLISKEELQ----------- 980
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTqlvgqhgrTAGAMQVEKAQlekeindrrle 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  981 -HEFDLLKKENEQRKRKLQAALINRK-ELLQRVSRLEEELANLKDQSKKEIPL---SESERGEVEEDKENKEYSEKCVTS 1055
Cdd:pfam15921  606 lQEFKILKDKKDAKIRELEARVSDLElEKVKLVNAGSERLRAVKDIKQERDQLlneVKTSRNELNSLSEDYEVLKRNFRN 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1056 KCQEIEIS---LKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEIsenQVIIQKLTTSNT 1132
Cdd:pfam15921  686 KSEEMETTtnkLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI---QFLEEAMTNANK 762


                   .
gi 1622909128 1133 D 1133
Cdd:pfam15921  763 E 763
PTZ00121 PTZ00121
MAEBL; Provisional
 1905-2530 2.20e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 2.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1905 EELSRVTKLKETAEEEKDDLEER---LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE--EEKQQLVK 1979
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERnneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKkaEEKKKADE 1306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1980 EKTKVESEIRKEYLEKiqgaqKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLE 2059
Cdd:PTZ00121  1307 AKKKAEEAKKADEAKK-----KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD 1381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2060 ITK---ENLAQAVEHRKKAQAELASFKVLlddTQSEAARVLADNLKLKKELQSNKESVK--SQMKQKDEDLERRLEQAEE 2134
Cdd:PTZ00121  1382 AAKkkaEEKKKADEAKKKAEEDKKKADEL---KKAAAAKKKADEAKKKAEEKKKADEAKkkAEEAKKADEAKKKAEEAKK 1458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2135 -KHLKEKKNMQEKLDALRR---EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQD-DRDRVIDE 2209
Cdd:PTZ00121  1459 aEEAKKKAEEAKKADEAKKkaeEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaEEAKKADE 1538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2210 AKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENK 2289
Cdd:PTZ00121  1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2290 ----ELLSQLEETRHLYHNSQN----------ELAKLESELNILKDQLTdlsnslEKCKEQKENLEGIiRQQEADIQNSK 2355
Cdd:PTZ00121  1619 kikaEELKKAEEEKKKVEQLKKkeaeekkkaeELKKAEEENKIKAAEEA------KKAEEDKKKAEEA-KKAEEDEKKAA 1691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2356 FSYEQLETDLQASRELTSRLHEEINMKEQkmislLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKK 2435
Cdd:PTZ00121  1692 EALKKEAEEAKKAEELKKKEAEEKKKAEE-----LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2436 AVDKTNQLMETLNAIK----KENIQQKAQLDSFVKSMSSL-------QNDRDRIVGDYQQLEerhlsvilekDQLIQEAA 2504
Cdd:PTZ00121  1767 EKKAEEIRKEKEAVIEeeldEEDEKRRMEVDKKIKDIFDNfaniiegGKEGNLVINDSKEME----------DSAIKEVA 1836

                          650       660
                   ....*....|....*....|....*.
gi 1622909128 2505 AENNKLKEEIRGLRSHMDDLNSENAK 2530
Cdd:PTZ00121  1837 DSKNMQLEEADAFEKHKFNKNNENGE 1862
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 63-611 5.09e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 5.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128   63 ELKDIIRQKDVQLQ-QKDEALQEEKKAADNKIKKLKLHAKAKLTSLNkHIEEMKAQGGTVLLTEPQSEEQLSKHDKSSTE 141
Cdd:COG1196    217 ELKEELKELEAELLlLKLRELEAELEELEAELEELEAELEELEAELA-ELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  142 EEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEfvmMKQQLQEKEELISTLQAQLSQtQAEQAAQVV 221
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE---LEEELEEAEEELEEAEAELAE-AEEALLEAE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  222 REKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESlvgRAQVVDLLQQELTAAEQRNQILSQQLQQI 301
Cdd:COG1196    372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL---EEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  302 EAEHNTLRNTVETEREESKILLEKMELEVAERKLsfhNLQEEMRHLLEQLEQAGQAQAELESRySALEQKHKAEMEEKTS 381
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAEL---LEELAEAAARLLLLLEAEADYEGFLE-GVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  382 HILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAqtIEQLEDQ---------LQQKSKEISQFLNRLPLQQHETAS 452
Cdd:COG1196    525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA--IEYLKAAkagratflpLDKIRARAALAAALARGAIGAAVD 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  453 QTCFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRIGEADREVSEISIV 532
Cdd:COG1196    603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909128  533 DDANKRSSSTEESGQDVLENtfSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEGDHEVLDQKEMKQMEGEGIAPI 611
Cdd:COG1196    683 ELAERLAEEELELEEALLAE--EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP 759
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 914-1765 5.53e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 5.53e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  914 EKMVQLNEEKFSLGVEIKTLKEQ-LNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagLISKEELQHEFDLLKKENEQ 992
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQeLKLKEQAKKALEYYQLKEKLELEEEYLLYLDY----LKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  993 RKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKE 1072
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1073 VELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPP 1152
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1153 G-TDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1231
Cdd:pfam02463  412 ElARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLS 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1232 GDQLRQLQIQVRESIDG--KLPSPDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDA-----SALQGGT 1304
Cdd:pfam02463  492 RQKLEERSQKESKARSGlkVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEveerqKLVRALT 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1305 SVAQIKAQLKEIETEKEKLELKISSTTSELT--------KKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKL 1376
Cdd:pfam02463  572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPIlnlaqldkATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1377 ESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERI 1456
Cdd:pfam02463  652 VSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQ 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1457 KQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEK 1536
Cdd:pfam02463  732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1537 DRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKE 1616
Cdd:pfam02463  812 EEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESK 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1617 YEillqsyenvsneaeriqhvvEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEE 1696
Cdd:pfam02463  892 EE--------------------KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKE 951

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909128 1697 ENDRLRAEVHPAGGTAKEcmETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQL 1765
Cdd:pfam02463  952 ENNKEEEEERNKRLLLAK--EELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1949-2762 1.29e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 1.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1949 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2028
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2029 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2108
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2109 SNKESVKSQMKQKDEDLERRL------EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2182
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREaeeeeeEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2183 dstvaQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHD 2262
Cdd:pfam02463  412 -----ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2263 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILK--DQLTDLSNSLEKCKEQKENL 2340
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAisTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2341 EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS 2420
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2421 QEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLI 2500
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2501 QEAAAENNKLKEEIR----------GLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNK 2570
Cdd:pfam02463  727 VQEAQDKINEELKLLkqkideeeeeEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2571 YAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALL 2650
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2651 SSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKD 2730
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1622909128 2731 LTAQIQSFGRSMSSLQNSRDHANEELDELKRK 2762
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
PTZ00121 PTZ00121
MAEBL; Provisional
 704-1231 8.54e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.15  E-value: 8.54e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  704 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQ 781
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  782 RRFDYESQTAHHNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 854
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  855 RVRHISSKVEELSQA--LSQKELEIAKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 930
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  931 KTLKEqlnlLSRAEEAKKEQVEEDNEVvsglKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1010
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1011 VSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEE 1090
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1091 QLQAlvKEMNQTLQDKTNQIDLLQAEISENQviiqklttsntdasdgdsvalvketvvisppgtdsgehwKPELEEKILA 1170
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909128 1171 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1231
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 346-1126 4.02e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.81  E-value: 4.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  346 HLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQL 425
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  426 -------EDQLQQKSKEISQFlnRLPLQQHETASQ---TCFPDVYNEGTQAVTEENIAS----------LQKRVVELENE 485
Cdd:pfam15921  155 eaakclkEDMLEDSNTQIEQL--RKMMLSHEGVLQeirSILVDFEEASGKKIYEHDSMStmhfrslgsaISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  486 ----KGALLLSSIELEELKAENEKlSSQITLLEAQNRIGEADREvSEISIVDDANKRSS--STEESGQDVLENTFSQKHK 559
Cdd:pfam15921  233 isylKGRIFPVEDQLEALKSESQN-KIELLLQQHQDRIEQLISE-HEVEITGLTEKASSarSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  560 ELSVLLLEMKEAQEEIAFLKLQL-QGKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDTGQNFPLMPNEESSLPAVE 638
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRSELrEAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKRE 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  639 KEQASTEHQNR------TSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQIlelelnfhkaqeiyeKN 712
Cdd:pfam15921  391 KELSLEKEQNKrlwdrdTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI---------------QG 455

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  713 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSvvTELRAQVRQLEMNLAEAERQR-RFDYESQTA 791
Cdd:pfam15921  456 KNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLT--ASLQEKERAIEATNAEITKLRsRVDLKLQEL 533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  792 HHnLLTEQIHslsieakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS 871
Cdd:pfam15921  534 QH-LKNEGDH------------LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIN 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  872 QKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKM---VQLNEEKFSLGVEIKTLKEQLNLLSraeeakk 948
Cdd:pfam15921  601 DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLS------- 673

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  949 eqveEDNEVvsgLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELAnlkdqskke 1028
Cdd:pfam15921  674 ----EDYEV---LKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQIT--------- 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1029 iplseSERGEVEEDKENKEYSEKCVTSKCQEIEIsLKQTISEKEVELEHIRKDlEEKMAAE-EQLQALVKEMNQTLQDKT 1107
Cdd:pfam15921  738 -----AKRGQIDALQSKIQFLEEAMTNANKEKHF-LKEEKNKLSQELSTVATE-KNKMAGElEVLRSQERRLKEKVANME 810

                          810
                   ....*....|....*....
gi 1622909128 1108 NQIDLLQAEISENQVIIQK 1126
Cdd:pfam15921  811 VALDKASLQFAECQDIIQR 829
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2680-2906 9.49e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 9.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2680 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDEL 2759
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2760 KRKYDASLKELAQLKEQQGLLnrerhALLSETTFSMDLpeeNSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSK 2839
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLA-----LLLSPEDFLDAV---RRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 2840 AMASLQNERDHLWNELEKFRKSEEGKQRSAAQpatslaEVQSLKKAMSSLQNDRDRLLKELKNLQQQ 2906
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIARLEAE 235
mukB PRK04863
chromosome partition protein MukB;
2697-3020 1.94e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 1.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2697 RNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDH------------------------- 2751
Cdd:PRK04863   292 RRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQqekieryqadleeleerleeqnevv 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2752 --ANEELDELKRKYDASLKELAQLKEQ-----QGLLNRERHAL-----------LSETTFSMDLPEENSLSYLEKLNQQL 2813
Cdd:PRK04863   372 eeADEQQEENEARAEAAEEEVDELKSQladyqQALDVQQTRAIqyqqavqalerAKQLCGLPDLTADNAEDWLEEFQAKE 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2814 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQN-----ERDHLWNE-LEKFRKSEEgkQRSAAQPATSL-AEVQSLKKAM 2886
Cdd:PRK04863   452 QEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKiagevSRSEAWDVaRELLRRLRE--QRHLAEQLQQLrMRLSELEQRL 529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2887 sSLQNDRDRLLKELKNLQQQYLQINQEITELR-PLKAQLQEYQDKTKTFQIMQEELRQENLSWQHELHQLRMEKSSW-EI 2964
Cdd:PRK04863   530 -RQQQRAERLLAEFCKRLGKNLDDEDELEQLQeELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWlAA 608

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909128 2965 HER--RMKEQYLMAISDKDQQVSHLQNLIRELRS-------SSSQAQPLKVQYQRQASPETSASP 3020
Cdd:PRK04863   609 QDAlaRLREQSGEEFEDSQDVTEYMQQLLEREREltverdeLAARKQALDEEIERLSQPGGSEDP 673
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2562-3083 1.45e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 1.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2562 QQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLS-------KEIESLKVSVSQLTRQVTALQEEGTLGIYHA 2634
Cdd:pfam15921  138 QSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMlshegvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRS 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2635 QLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLhhdagIMRNETE-TAEERVAELARD 2713
Cdd:pfam15921  218 LGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQL-----ISEHEVEiTGLTEKASSARS 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2714 LVEMEQKLLMVTKENKdlTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELA------------------QLKE 2775
Cdd:pfam15921  293 QANSIQSQLEIIQEQA--RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlanseltearterdQFSQ 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2776 QQGLLNRERHALLSETTfsmdlPEENSLSYLEKLNQQLLSKDE----QLLHLSSQLEDSYNQVQ---------------S 2836
Cdd:pfam15921  371 ESGNLDDQLQKLLADLH-----KREKELSLEKEQNKRLWDRDTgnsiTIDHLRRELDDRNMEVQrleallkamksecqgQ 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2837 FSKAMASLQNERDHLWN--------------------ELEKFRKSEEGKQRSAAQPATSLAE----VQSLKKAMSSLQND 2892
Cdd:pfam15921  446 MERQMAAIQGKNESLEKvssltaqlestkemlrkvveELTAKKMTLESSERTVSDLTASLQEkeraIEATNAEITKLRSR 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2893 RDRLLKELKNLQQQYLQINQEITELRPLKAQLQEyqdKTKTFQIMQEELRQ-ENLSWQH-------ELHQLRMEKsswEI 2964
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAE---KDKVIEILRQQIENmTQLVGQHgrtagamQVEKAQLEK---EI 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2965 HERRMKEQYLMAISDKDQQVshlqnlIRELRSSSSQAQPLKVQYQRQASPETSASPDGSQ---NLIYETELLRNQLNdSL 3041
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAK------IRELEARVSDLELEKVKLVNAGSERLRAVKDIKQerdQLLNEVKTSRNELN-SL 672

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1622909128 3042 KEihQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQ 3083
Cdd:pfam15921  673 SE--DYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712
PRK11281 PRK11281
mechanosensitive channel MscK;
186-510 2.59e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.75  E-value: 2.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  186 KEFVMMKQQLQEKEELISTLQAQLSQTQAeQAAQVVREkdaRFETqvrLHEDELLQLVTQadVETEMQQklrvLQRKLEE 265
Cdd:PRK11281    80 EETEQLKQQLAQAPAKLRQAQAELEALKD-DNDEETRE---TLST---LSLRQLESRLAQ--TLDQLQN----AQNDLAE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  266 HEESLVGRAQVVDLLQQELTAAEQRnqilsqqlqqIEAEHNTLRNTVETEREESKILLEKMELEvaerkLSFHNLQEEMR 345
Cdd:PRK11281   147 YNSQLVSLQTQPERAQAALYANSQR----------LQQIRNLLKGGKVGGKALRPSQRVLLQAE-----QALLNAQNDLQ 211

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  346 HLL----EQLEQAGQAQAELESRYSALEQKHKAEMEEKTSH---ILSlQKTGQELQSACDALKDQNSKLLQDKDEQAVQS 418
Cdd:PRK11281   212 RKSlegnTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAINSkrlTLS-EKTVQEAQSQDEAARIQANPLVAQELEINLQL 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  419 AQT-IEQLE--DQLQQKSKEISQFLNRlpLQQhetasqtcfpdvynegTQAVTEENIASLQkrvvelenekGALLLSSIE 495
Cdd:PRK11281   291 SQRlLKATEklNTLTQQNLRVKNWLDR--LTQ----------------SERNIKEQISVLK----------GSLLLSRIL 342

                          330       340
                   ....*....|....*....|
gi 1622909128  496 LEELKA-----ENEKLSSQI 510
Cdd:PRK11281   343 YQQQQAlpsadLIEGLADRI 362
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2039-2208 3.46e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 42.67  E-value: 3.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2039 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2114
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2115 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2171
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1622909128 2172 DKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2208
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 155-427 6.86e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 42.51  E-value: 6.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  155 EKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKefvmmKQQL-QEKEEL---ISTLQAQLSQT-QAEQAAQVVREKDArFE 229
Cdd:NF012221  1539 ESSQQADAVSKHAKQDDAAQNALADKERAEAD-----RQRLeQEKQQQlaaISGSQSQLESTdQNALETNGQAQRDA-IL 1612

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  230 TQVRLHEDELLQLVTQADV---------ETEMQQKLRVLQRKLEEHEESLVGRAQVVdllQQELTAAEQRNqilsqqlqq 300
Cdd:NF012221  1613 EESRAVTKELTTLAQGLDAldsqatyagESGDQWRNPFAGGLLDRVQEQLDDAKKIS---GKQLADAKQRH--------- 1680

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  301 iEAEHNTLRNTVetereeskillEKMELEVAErklSFHNLQEemrhlleqLEQAG-QAQAELESRYS-ALEQKHKAEMEE 378
Cdd:NF012221  1681 -VDNQQKVKDAV-----------AKSEAGVAQ---GEQNQAN--------AEQDIdDAKADAEKRKDdALAKQNEAQQAE 1737

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1622909128  379 KTSHILSlqktgQELQSAcdalKDQNSKLLQDKDEQAVQSAQTIEQLED 427
Cdd:NF012221  1738 SDANAAA-----NDAQSR----GEQDASAAENKANQAQADAKGAKQDES 1777
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1903-2775 1.85e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 1.85e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1903 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1972
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1973 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2045
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2046 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD---------DTQSEAARVLADNLK------------LK 2104
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEeleaeleelESRLEELEEQLETLRskvaqlelqiasLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2105 KELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2184
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2185 TVAQLAAFTKSMSSLQDDRDRV------IDEAKKWERKFSDAIQTKEEEIRLKE--ENCSVLKDQLRQMSIHMEELKINI 2256
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLegfsegVKALLKNQSGLSGILGVLSELISVDEgyEAAIEAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2257 SRLEHDKQIWESKAqTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQL---TDLSNSLEKC 2333
Cdd:TIGR02168  560 KAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2334 KeqKENLEGIIRQQEADIQNSKFSYEQletdlQASRELTSRLHEEINMKE-QKMISLLSGKEEAIQVAIAELRQQHDkei 2412
Cdd:TIGR02168  639 K--KLRPGYRIVTLDGDLVRPGGVITG-----GSAKTNSSILERRREIEElEEKIEELEEKIAELEKALAELRKELE--- 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2413 kELENLLSQEeeenivleeenkkavdktnqlmetlnaikkeniqqKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsv 2492
Cdd:TIGR02168  709 -ELEEELEQL-----------------------------------RKELEELSRQISALRKDLARLEAEVEQLEER---- 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2493 ILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleaqlqqnKELKNKYA 2572
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAA 820

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2573 KLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyhaqLKVKEEELQRLSALLSS 2652
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALAL 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2653 SQKRITELEEELvcvqKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKEN 2728
Cdd:TIGR02168  892 LRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDE 967

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909128 2729 KDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2775
Cdd:TIGR02168  968 EEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1304-2089 4.13e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.52  E-value: 4.13e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1304 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGL-EIESLKTASHEAEVRAESLQQKLESSQLQ 1382
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1383 iaglehLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1459
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1460 QVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARDTIEHLTKSLADVESH 1528
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1529 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEG-------LTEDKEKLVKEIESLKSSKIA 1601
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqLGSVGERYATAIEVAAGNRLN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1602 ----ESSEWQEKHKELQKEYEILLQSYENVsNEAERIQHVVEAVRQEKQELYGklrsteANKKETEKQLQEAEKEMEEMK 1677
Cdd:TIGR02169  551 nvvvEDDAVAKEAIELLKRRKAGRATFLPL-NKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1678 EKMRKFAKSKQQ--KILELEEENDRLRAEVHPAGGTAKECMETLLSsnASMKEEVERVKMEYETLSKKFQSLMSEKDSLS 1755
Cdd:TIGR02169  624 LVVEDIEAARRLmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFS--RSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1756 EEVQDLKHQLESnvsKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSlsmstrpacsesvpsensanpavsedvSSHD 1835
Cdd:TIGR02169  702 NRLDELSQELSD---ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS---------------------------SLEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1836 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAllSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE 1915
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1916 TAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1995
Cdd:TIGR02169  830 YLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1996 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR-------------YQEKISALERTVKALEFVQTESQKDLEITK 2062
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelsledVQAELQRVEEEIRALEPVNMLAIQEYEEVL 985

                          810       820
                   ....*....|....*....|....*..
gi 1622909128 2063 ENLAQAVEHRKKAQAELASFKVLLDDT 2089
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1320-2182 9.27e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 94.35  E-value: 9.27e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1320 KEKLELKISSTTSELTkkseevfQLQDQINKQGLEIESLKTASHEAEvRAESLQQKLESSQLQIAGLEhLRELQPELDEL 1399
Cdd:TIGR02168  174 RKETERKLERTRENLD-------RLEDILNELERQLKSLERQAEKAE-RYKELKAELRELELALLVLR-LEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1400 QKLISEKEEDVSYLSGQLREKEAALTKIQTEiieqedlikalHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEEsra 1479
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLE-----------VSELEEEIEELQKELYALANEISRLEQQKQILRER--- 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1480 KQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMDR 1559
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1560 SLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESL-KSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVV 1638
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERLQQEIEELlKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1639 EAVRQEKQELYGKLRSTEANKKETEKQLQEaekemeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGgtakecmeT 1718
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQEN---------------LEGFSEGVKALLKNQSGLSGILGVLS--------E 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1719 LLSSNASMKEEVERVkmeyetLSKKFQSLMSEkdSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTE-EATQSIPG 1797
Cdd:TIGR02168  528 LISVDEGYEAAIEAA------LGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDrEILKNIEG 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1798 etedqdslsmsTRPACSESVPSENSANPAVS---EDVSSHDEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENER 1872
Cdd:TIGR02168  600 -----------FLGVAKDLVKFDPKLRKALSyllGGVLVVDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAK 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1873 NAllSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIK 1952
Cdd:TIGR02168  668 TN--SSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAE 741

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1953 NELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCI 2031
Cdd:TIGR02168  742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAA 820

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2032 RYQEKISALERTVKALEfvqtesqKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNK 2111
Cdd:TIGR02168  821 NLRERLESLERRIAATE-------RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEAL 889

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909128 2112 ESVKSQMKQKDEDLerrleqaeekhlkekKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2182
Cdd:TIGR02168  890 ALLRSELEELSEEL---------------RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 760-1648 2.27e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.27e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  760 VVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLsieakskdvkievlQNELDDVQLQFSEQSTLIRSLQ 839
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL--------------REELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  840 SQLQNKESEvlegaervrhisskveelsqaLSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQL 919
Cdd:TIGR02168  260 AELQELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  920 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAglisKEELQHEFDLLKKENEQRKRKLQA 999
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1000 ALINRKELLQRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIR 1079
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1080 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASdgdsvALVKETVVISPPGTDSGEH 1159
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK-----ALLKNQSGLSGILGVLSEL 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1160 WKPElEEKILALEKekeQLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIG 1232
Cdd:TIGR02168  529 ISVD-EGYEAAIEA---ALGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1233 DQLRQLQIQVRESIDGKLPSpdqqewCSPTPGLEEplfkATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQ 1308
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLGG------VLVVDDLDN----ALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILE 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1309 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEH 1388
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1389 lrelqpELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHderiKQLQVELCEMKQ 1468
Cdd:TIGR02168  755 ------ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL----TLLNEEAANLRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1469 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEhltkslADVESHVsaqnKEKDRVLGRLALLQE 1548
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE------SELEALL----NERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1549 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEssewqekhkELQKEYEILLQSYENVS 1628
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIE 964

                          890       900
                   ....*....|....*....|
gi 1622909128 1629 NEAERIQHVVEAVRQEKQEL 1648
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 685-1535 3.07e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 3.07e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  685 QDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV-VTE 763
Cdd:TIGR02168  192 EDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEkLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  764 LRAQVRQLEMNLAEAerQRRFdyesqtahhnllteqiHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQ 843
Cdd:TIGR02168  272 LRLEVSELEEEIEEL--QKEL----------------YALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  844 NKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEK 923
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL----NNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  924 FSLGVEIKTLKEQLN-LLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALI 1002
Cdd:TIGR02168  410 ERLEDRRERLQQEIEeLLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1003 NRKELLQRVSRLEEELANLKDQSKKEIPLSE-----SERGEVEEDKEN------KEYSEKCVTSKCQEIEI---SLKQTI 1068
Cdd:TIGR02168  490 RLDSLERLQENLEGFSEGVKALLKNQSGLSGilgvlSELISVDEGYEAaieaalGGRLQAVVVENLNAAKKaiaFLKQNE 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1069 SEKEVELE-------HIRKDLEEKMAAEEQLQALVKEmnqtLQDKTNQIDLLQAEISENQVIIQKLTTSNTDAS--DGDS 1139
Cdd:TIGR02168  570 LGRVTFLPldsikgtEIQGNDREILKNIEGFLGVAKD----LVKFDPKLRKALSYLLGGVLVVDDLDNALELAKklRPGY 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1140 VALVKETVVISPPGTDSGEHWKPELeeKILALEKEKEQLQKKLqEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQE 1219
Cdd:TIGR02168  646 RIVTLDGDLVRPGGVITGGSAKTNS--SILERRREIEELEEKI-EELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1220 QFDEQSKENENIGDQLRQLQIQVRESIDgkLPSPDQQEWCSPTPGLEEPLFKATEQhhtqpvlesnlcpdwpshsedasa 1299
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIA--QLSKELTELEAEIEELEERLEEAEEE------------------------ 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1300 lqggtsVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESS 1379
Cdd:TIGR02168  777 ------LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1380 QLQIAGLEH--------LRELQPELDELQKLISEKEEDVSY-------LSGQLREKEAALTKIQTEIIEQEDLIKALHTQ 1444
Cdd:TIGR02168  851 SEDIESLAAeieeleelIEELESELEALLNERASLEEALALlrseleeLSEELRELESKRSELRRELEELREKLAQLELR 930

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1445 L---EMQAKEHDERI-KQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARDTIE 1516
Cdd:TIGR02168  931 LeglEVRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKE 1010

                          890
                   ....*....|....*....
gi 1622909128 1517 HLTKSLADVESHVSAQNKE 1535
Cdd:TIGR02168 1011 DLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1308-2082 3.67e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 3.67e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1308 QIKAQLKEIE-----TEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQ 1382
Cdd:TIGR02168  217 ELKAELRELElallvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1383 IAGLEH-LRELQPELDELQKLISEKEEdvsylsgQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQv 1461
Cdd:TIGR02168  297 ISRLEQqKQILRERLANLERQLEELEA-------QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE- 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1462 elcEMKQKPEEIEEESRAKQQiqrklqaaliSRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNK-----EK 1536
Cdd:TIGR02168  369 ---ELESRLEELEEQLETLRS----------KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKkleeaEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1537 DRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKS-----SKIAESSEWQEKHK 1611
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqenlEGFSEGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1612 ELQKEYEILLQSYENVSNE---------AERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRK 1682
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILK 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1683 FAKSKQQKILELEEENDRLRAEVHPAGGTAKeCMETLLSSNA---SMKEEVERVKMEYETLSKKF----------QSLMS 1749
Cdd:TIGR02168  596 NIEGFLGVAKDLVKFDPKLRKALSYLLGGVL-VVDDLDNALElakKLRPGYRIVTLDGDLVRPGGvitggsaktnSSILE 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1750 EKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQM-NVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVS 1828
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELeEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1829 EDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELS 1908
Cdd:TIGR02168  755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1909 RVTKLKETAEEEKDDLEErlmnQLAELNGSIgnycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEI 1988
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSE----DIESLAAEI-------EELEELIEELESELEALLNERASLEEALALLRSELEELSEEL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1989 RKEylekiqgaqkepgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2068
Cdd:TIGR02168  904 REL--------------ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969

                          810
                   ....*....|....*
gi 1622909128 2069 VEHR-KKAQAELASF 2082
Cdd:TIGR02168  970 ARRRlKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2018-2926 4.58e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 4.58e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2018 EKQQEVKQLQKDC----IRYQEKISALERTVKALEFVQTESQkdLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEA 2093
Cdd:TIGR02168  199 ERQLKSLERQAEKaeryKELKAELRELELALLVLRLEELREE--LEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2094 ARVLADNLKLKKELQSnkesvksqMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDK 2173
Cdd:TIGR02168  277 SELEEEIEELQKELYA--------LANEISRLEQQKQILRER----LANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2174 EIQQVQENLDSTVAQLAAFTKSmssLQDDRDRVIDEAKKWERKFSDAIQTKEEEirlkeencSVLKDQLRQMSIHMEELK 2253
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAE---LEELESRLEELEEQLETLRSKVAQLELQI--------ASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2254 INISRLEHDKQIWESKAQ-TEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEK 2332
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2333 CKEQKENLEGIIRQQEADIQNSkfsyEQLETDLQASRELtsrlheeinmkeqkmISLLSGKEEAIQVAIAELRQQ----H 2408
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNQ----SGLSGILGVLSEL---------------ISVDEGYEAAIEAALGGRLQAvvveN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2409 DKEIKELENLLSQeeeenivleeenkKAVDKTNQLMETL---NAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2485
Cdd:TIGR02168  555 LNAAKKAIAFLKQ-------------NELGRVTFLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2486 eerhLSVILEKDQLiQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKqlLEAQLQQNK 2565
Cdd:TIGR02168  622 ----LGGVLVVDDL-DNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEK--IEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2566 ELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKEEELQR 2645
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE--LTELEAEIEELEERLEE 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2646 LSALLSSSQKRITELEEElVCVQKEAAKKVGEIEDKLKKELKHLHHDAGimrneteTAEERVAELARDLVEMEQKLLMVT 2725
Cdd:TIGR02168  773 AEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAA-------NLRERLESLERRIAATERRLEDLE 844

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2726 KENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRErhallsettfsmdlpeenslsy 2805
Cdd:TIGR02168  845 EQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE---------------------- 902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2806 LEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSfskamasLQNERDHLWNEL-EKFRKSEEGkqrSAAQPATSLAEVQSLKK 2884
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEG-------LEVRIDNLQERLsEEYSLTLEE---AEALENKIEDDEEEARR 972

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 1622909128 2885 AMSSLQNDRDRL-------LKELKNLQQQYLQINQEITELRPLKAQLQE 2926
Cdd:TIGR02168  973 RLKRLENKIKELgpvnlaaIEEYEELKERYDFLTAQKEDLTEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1834-2531 3.06e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 3.06e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1834 HDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKL 1913
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1914 KETAEEEKDDLEERLMNQLAELNGS---IGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1990
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELeekLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1991 EYLE-KIQGAQKEPGNKSHAKELQELLK-EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTEsqkdLEITKENLAQA 2068
Cdd:TIGR02168  398 LNNEiERLEARLERLEDRRERLQQEIEElLKKLEEAELKELQAELEELEEELEELQEELERLEEA----LEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2069 VEHRKKAQAELASFKVLLDDTQSEAARVL-----ADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK----E 2139
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEgfsegVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavvvE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2140 KKNMQEK-LDALRREKVH----LEETI---GEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSL------QDDRDR 2205
Cdd:TIGR02168  554 NLNAAKKaIAFLKQNELGrvtfLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2206 VIDEAKKW-----------------------ERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLE-- 2260
Cdd:TIGR02168  634 ALELAKKLrpgyrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEee 713

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2261 ---------------HDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTD 2325
Cdd:TIGR02168  714 leqlrkeleelsrqiSALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2326 LSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLlsgkeeaiQVAIAELR 2405
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL--------AAEIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2406 QQHDKEIKELENLLSQEEEENIVLEEENKKAvdktNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2485
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSEL----EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909128 2486 EERhlsvILEKDQLIQEAAAEN-NKLKEEIRGLRSHMDDLNSENAKL 2531
Cdd:TIGR02168  942 QER----LSEEYSLTLEEAEALeNKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2211-2944 3.39e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 3.39e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2211 KKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDkqiwESKAQTEVQLQQKVCDTLQGENKE 2290
Cdd:TIGR02168  203 KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEE----LEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2291 LLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRE 2370
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2371 LtsrlHEEINMKEQKMISLLSGKEEAIQV---AIAELRQQ---HDKEIKELENLLSQEEEENIVLEEENKKAVDKT---- 2440
Cdd:TIGR02168  359 E----LEELEAELEELESRLEELEEQLETlrsKVAQLELQiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLeeae 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2441 -NQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERH---------LSVILEKDQLIQEAAAENNKL 2510
Cdd:TIGR02168  435 lKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlqarldsLERLQENLEGFSEGVKALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2511 KEEIRGLRSHMDDLNSENAKLDAEL-IQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQ 2589
Cdd:TIGR02168  515 QSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2590 RSSNALQEEKRDLSKEIESLKVSVS--------------------QLTRQVTALQEEGTLgIYHAQLKVKEEELQRLSAL 2649
Cdd:TIGR02168  595 KNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldnalelakKLRPGYRIVTLDGDL-VRPGGVITGGSAKTNSSIL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2650 lsSSQKRITELEEELvcvqkeaaKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENK 2729
Cdd:TIGR02168  674 --ERRREIEELEEKI--------EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2730 DLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSEttfsmdlpeenslsyLEKL 2809
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA---------------LDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2810 NQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQrsaAQPATSLAEVQSLKKAMSSL 2889
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE---ELIEELESELEALLNERASL 885

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909128 2890 QNDRDRLLKELKNLQQQYLQINQEITELRplkAQLQEYQDKTKTFQIMQEELRQE 2944
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELR---RELEELREKLAQLELRLEGLEVR 937
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1308-1855 4.22e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 4.22e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1308 QIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE 1387
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1388 H-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1466
Cdd:COG1196    316 ErLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1467 KQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALL 1546
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1547 QEERDKLitemDRSLLENQSLSGSCESLKLALEGLTED-KEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYE 1625
Cdd:COG1196    476 EAALAEL----LEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1626 NVSNEAERIqhvvEAVRQEKQELYGK-----LRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDR 1700
Cdd:COG1196    552 VVEDDEVAA----AAIEYLKAAKAGRatflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1701 LRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEK 1780
Cdd:COG1196    628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909128 1781 HDNQMNVTEEATQSIpgETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLE 1855
Cdd:COG1196    708 ELAEAEEERLEEELE--EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 921-1761 4.66e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 4.66e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  921 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLkQNYDEmspagliSKEELQHEFDLLKKENEQRKRKLQAA 1000
Cdd:TIGR02168  222 LRELELALLVLRLEELREELEELQEELKEAEEELEELTAEL-QELEE-------KLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1001 LINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEiSLKQTISEKEVELEHIRK 1080
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE-SLEAELEELEAELEELES 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1081 DLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvisppGTDSGEHw 1160
Cdd:TIGR02168  373 RLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL------QAELEEL- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1161 KPELEEKILALEKEKEQLqKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLqEQFDEQSKENENIGDQLRQLQI 1240
Cdd:TIGR02168  446 EEELEELQEELERLEEAL-EELREELEEAEQALDAAERELAQLQARLDSLERLQENL-EGFSEGVKALLKNQSGLSGILG 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1241 QVRESIdgklpspdqqewcSPTPGLEEPLFKATEQHhTQPVLESNLCPDWPSHSEDASALQGGTSVAQIK----AQLKEI 1316
Cdd:TIGR02168  524 VLSELI-------------SVDEGYEAAIEAALGGR-LQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDsikgTEIQGN 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1317 ETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASH-----EAEVRAESLQQKLESSQLQIAGLEHLRE 1391
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALElakklRPGYRIVTLDGDLVRPGGVITGGSAKTN 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1392 LQP-----ELDELQKLISEKEEdvsylsgQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELcem 1466
Cdd:TIGR02168  670 SSIlerrrEIEELEEKIEELEE-------KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE--- 739

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1467 kqkpEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALL 1546
Cdd:TIGR02168  740 ----AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1547 QEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLksskiaessewQEKHKELQKEYEILLqsyen 1626
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL-----------EELIEELESELEALL----- 879

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1627 vsNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskQQKILELEEendRLRAEVH 1706
Cdd:TIGR02168  880 --NERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL----EVRIDNLQE---RLSEEYS 950

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909128 1707 PAGGTAKECMETLLSSNASMKEEVERVKM--------------EYETLSKKFQSLMSEKDSLSEEVQDL 1761
Cdd:TIGR02168  951 LTLEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaaieEYEELKERYDFLTAQKEDLTEAKETL 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2121-2958 1.48e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.87  E-value: 1.48e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2121 KDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTV----AQLAAFTK 2194
Cdd:TIGR02168  153 KPEERRAIFEEAAgiSKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAelreLELALLVL 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2195 SMSSLQDDRDRVIDEAKKWERKFSDA---IQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQ 2271
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELtaeLQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2272 TEVQLQQKVCDTLQgenkELLSQLEETrhlyhnsQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADI 2351
Cdd:TIGR02168  313 NLERQLEELEAQLE----ELESKLDEL-------AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2352 QNSKFSYEQLETDLQASRELTSRLHEEINMKEQKmisllsgKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENivlee 2431
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDR-------RERLQQEIEELLKKLEEAELKELQAELEELEEEL----- 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2432 enKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsvilekdqlIQEAAAENNKLK 2511
Cdd:TIGR02168  450 --EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG------------FSEGVKALLKNQ 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2512 EEIRGLRSHMDDLNSENAKLDAEL-IQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQR 2590
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2591 SSNALQEEKRDLSKEIESLKVSVS--------------------QLTRQVTALQEEGTLgIYHAQLKVKEEELQRLSALl 2650
Cdd:TIGR02168  596 NIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldnalelakKLRPGYRIVTLDGDL-VRPGGVITGGSAKTNSSIL- 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2651 sSSQKRITELEEELvcvqkeaaKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKD 2730
Cdd:TIGR02168  674 -ERRREIEELEEKI--------EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2731 LTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSE-TTFSMDLPEENS-----LS 2804
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAlDELRAELTLLNEeaanlRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2805 YLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFrksEEGKQRSAAQPATSLAEVQSLKK 2884
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL---LNERASLEEALALLRSELEELSE 901

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909128 2885 AMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQE-----YQDKTKTFQIMQEELRQENLSWQHELHQLRME 2958
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseeYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 215-1035 1.83e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.83e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  215 EQAAQVVREKDARFETQVRLHE-DELLQLVTqaDVETEMQQKLRVLQRK---------LEEHEESLVGRAQVVDLlqQEL 284
Cdd:TIGR02168  162 EEAAGISKYKERRKETERKLERtRENLDRLE--DILNELERQLKSLERQaekaerykeLKAELRELELALLVLRL--EEL 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  285 TAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQAELESR 364
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  365 YSALE---QKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKllqdKDEQAVQSAQTIEQLEDQLQQKSKEISQFLN 441
Cdd:TIGR02168  318 LEELEaqlEELESKLDELAEELAELEEKLEELKEELESLEAELEE----LEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  442 RLPLQQHETasqtcfpdVYNEGTQAVTEENIASLQKRVVELENE--KGALLLSSIELEELKAENEKLSSQitLLEAQNRI 519
Cdd:TIGR02168  394 QIASLNNEI--------ERLEARLERLEDRRERLQQEIEELLKKleEAELKELQAELEELEEELEELQEE--LERLEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  520 GEADREVSEISIVDDANKRSSSTEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEGDH---EVLD 596
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEaaiEAAL 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  597 QKEMKQMEGEGIAPIKMEV-FLEDTGQ---NFPLMPNEESSLPAVEKEQASTEHQNRTSEEISLNDAGVELKSTKQDCDK 672
Cdd:TIGR02168  544 GGRLQAVVVENLNAAKKAIaFLKQNELgrvTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLG 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  673 SLSAVPDIgqchqDELERLKSQILELELNFHKAQEIY-------------EKNLDEKAKEISNLNQLIEEFKKNADNNSS 739
Cdd:TIGR02168  624 GVLVVDDL-----DNALELAKKLRPGYRIVTLDGDLVrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  740 AFTALSEERDQLLAQVKEL-SVVTELRAQVRQLEMNLAEAERQrrfdyesqtahHNLLTEQIHSLSIEAKSKDVKIEVLQ 818
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLrKELEELSRQISALRKDLARLEAE-----------VEQLEERIAQLSKELTELEAEIEELE 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  819 NELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTI 898
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  899 EEKDQQVTEISFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSpagliskeE 978
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEELSEELRELESKRS--------E 912

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128  979 LQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESE 1035
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1344-1928 1.85e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.37  E-value: 1.85e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1344 LQDQINKQgleIESLKTashEAEV--RAESLQQKLESSQLQIAGLeHLRELQPELDELQKLISEKEEDVSYLSGQLREKE 1421
Cdd:COG1196    194 ILGELERQ---LEPLER---QAEKaeRYRELKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1422 AALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKEN 1501
Cdd:COG1196    267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1502 KSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMdrsllenqslsgscESLKLALEGL 1581
Cdd:COG1196    347 EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL--------------EELEEAEEAL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1582 TEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKE 1661
Cdd:COG1196    413 LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1662 TEKQLQEAEKEMEEMKEKMRKFAKSKQQKILEL----------------EEENDRLRAEVHPAGGTAKECMETLLSSNAS 1725
Cdd:COG1196    493 LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvavligveaayeaaleAALAAALQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1726 MKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEAT--EKHDNQMNVTEEATQSIPGETEDQD 1803
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtlVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1804 SLSMSTRPACSESVPSENSANPAVSEDVSShdeinnylQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKD 1883
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELE--------ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1622909128 1884 GELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERL 1928
Cdd:COG1196    725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 193-1021 2.28e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.10  E-value: 2.28e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  193 QQLQEKEELISTLQAQLSQTQAEQAaqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVG 272
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  273 RAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAErklsfhnLQEEMRHLLEQLE 352
Cdd:TIGR02168  289 ELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE-------LKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  353 QAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQsacdalkdQNSKLLQDKDEQAVQSAQTIEQLEDQLQ-Q 431
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE--------RLEARLERLEDRRERLQQEIEELLKKLEeA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  432 KSKEISQFLNRLPLQQHETasQTCFPDVYNEGTQAvtEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQI- 510
Cdd:TIGR02168  434 ELKELQAELEELEEELEEL--QEELERLEEALEEL--REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVk 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  511 TLLEAQNRIGEADREVSEISIVDDANKRSSST--EESGQDVLENTFSQKHKELSVLLlemKEAQEEIAFLKLQLQGKRAE 588
Cdd:TIGR02168  510 ALLKNQSGLSGILGVLSELISVDEGYEAAIEAalGGRLQAVVVENLNAAKKAIAFLK---QNELGRVTFLPLDSIKGTEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  589 EGDHEVLdQKEMKQMEGEGIAPIKMEVFLEDTGQNFplmpneESSLPAVEKEQASTEHQNRTSEEISLNDAGVELKS--- 665
Cdd:TIGR02168  587 QGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRpgg 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  666 --TKQDCDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTA 743
Cdd:TIGR02168  660 viTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELEQLRKELEELSRQISA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  744 LSEERDQLLAQVKELSvvtelrAQVRQLEMNLAEAERQRrfdyesqtahhNLLTEQIHSLSIEAKSKDVKIEVLQNELDD 823
Cdd:TIGR02168  731 LRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  824 VQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQ 903
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELES 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  904 QVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspaglisKEELQ 980
Cdd:TIGR02168  874 ELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL-------QERLS 946

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 1622909128  981 HEFDLLKKENEQRKRKLQAALinrKELLQRVSRLEEELANL 1021
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDE---EEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1840-2366 5.11e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 5.11e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1840 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEE 1919
Cdd:COG1196    230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1920 EKDDLE---ERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKI 1996
Cdd:COG1196    310 RRRELEerlEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1997 QGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQ 2076
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2077 AELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALRR 2152
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2153 EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKE 2232
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2233 ENC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNS 2305
Cdd:COG1196    630 ARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909128 2306 QNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQ 2366
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 811-1596 3.86e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.87  E-value: 3.86e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  811 DVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEvLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEkkRD 890
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLKEKEALERQKEAIE--RQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  891 VETLQQTIEEKDQQVTEISFSMTEKMVQLNE-----------EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVS 959
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEElnkkikdlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  960 GLKQNYDEMspagLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSK---KEIPLSESER 1036
Cdd:TIGR02169  326 KLEAEIDKL----LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKdyrEKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1037 GEVEEDKENKEYSEKCVTSKCQEIEI---SLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLL 1113
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAaiaGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1114 QAEISENQVIIQKL----TTSNTDASDGDSVALVKETVVISPPGTDSgehwkpEL----EEKILALEK-----------E 1174
Cdd:TIGR02169  482 EKELSKLQRELAEAeaqaRASEERVRGGRAVEEVLKASIQGVHGTVA------QLgsvgERYATAIEVaagnrlnnvvvE 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1175 KEQLQKKLQEALTSRKA------ILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKE--NENIGDQLrqlqiqVRESI 1246
Cdd:TIGR02169  556 DDAVAKEAIELLKRRKAgratflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafKYVFGDTL------VVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1247 DGKLPSPDQQEWCSPTPGLEEPLFKATEQHHTQPVLESN---LCPDWPSHSEDASALQGGTSVAQIK------------A 1311
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFsrsEPAELQRLRERLEGLKRELSSLQSElrrienrldelsQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1312 QLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHlRE 1391
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA-RL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1392 LQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQ---LEMQAKEHDERIKQLQVELCEMKQ 1468
Cdd:TIGR02169  789 SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQridLKEQIKSIEKEIENLNGKKEELEE 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1469 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGR------ 1542
Cdd:TIGR02169  869 ELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipe 948

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909128 1543 ----LALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLK 1596
Cdd:TIGR02169  949 eelsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1572-2396 7.17e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 7.17e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1572 ESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQE---KHKELQKEYEILLQSYENVSNEAERIQhvveavrQEKQEL 1648
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRLE-------QQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1649 YGKLRSTEANKKETEKQLQEAekemeemkekmrkfakskQQKILELEEENDRLRAEVhpagGTAKECMETLLSSNASMKE 1728
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEEL------------------ESKLDELAEELAELEEKL----EELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1729 EVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEA------TEKHDNQMNVTEEATQSIPGETEDQ 1802
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDrrerlqQEIEELLKKLEEAELKELQAELEEL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1803 DSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAL------L 1876
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvL 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1877 SQISTKDGELKLLQEEV--------------SKMNLLNQQIQEELSRVTKLKETAEEEkDDLEERLMNQLAELNGSIGnY 1942
Cdd:TIGR02168  526 SELISVDEGYEAAIEAAlggrlqavvvenlnAAKKAIAFLKQNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG-V 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1943 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHA---------KELQ 2013
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2014 ELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASfkvlLDDTQSEA 2093
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTEL 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2094 ARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDK 2173
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2174 EIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWerkfSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELK 2253
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERASLEEALALLRSELEELSEELRELESKRSELR 914

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2254 INISRL-EHDKQIWESKAQTEVQLQQkvcdTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSN---- 2328
Cdd:TIGR02168  915 RELEELrEKLAQLELRLEGLEVRIDN----LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnla 990

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909128 2329 SLEKCKEQKENLEgIIRQQEADIQNSKFSYEQLETDLqaSRELTSRLHE---EINMKEQKMISLLSGKEEA 2396
Cdd:TIGR02168  991 AIEEYEELKERYD-FLTAQKEDLTEAKETLEEAIEEI--DREARERFKDtfdQVNENFQRVFPKLFGGGEA 1058
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1167-1990 7.42e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 7.42e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1167 KILALEKEKEQLQKKLQEALTSRKAILKKAQEKErhlrEELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREsI 1246
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI-L 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1247 DGKLPSPDQQEwcsptpgleEPLFKATEQHHTQPVLESNLCPDWPSHSEDASAlqggtSVAQIKAQLKEIETEKEKLELK 1326
Cdd:TIGR02168  308 RERLANLERQL---------EELEAQLEELESKLDELAEELAELEEKLEELKE-----ELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1327 ISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEhLRELQPELDELQKLISEK 1406
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE-LKELQAELEELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1407 EEDVSYLSGQLREKEAALTKIQTEIieqedlikalhTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEEsrAKQQIQRK 1486
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQAL-----------DAAERELAQLQARLDSLERLQENLEGFSEGVKAL--LKNQSGLS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1487 LQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKdrvLGRLAL--LQEERDKLITEMDRSLLEN 1564
Cdd:TIGR02168  520 GILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNE---LGRVTFlpLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1565 QslsgscESLKLALEGLTEDKEKLVKEIESLKS-SKIAES-SEWQEKHKELQKEYEI------LLQSYENVSNEAERIQH 1636
Cdd:TIGR02168  597 I------EGFLGVAKDLVKFDPKLRKALSYLLGgVLVVDDlDNALELAKKLRPGYRIvtldgdLVRPGGVITGGSAKTNS 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1637 VVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAK---SKQQKILELEEENDRLRAEVhpagGTAK 1713
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKeleELSRQISALRKDLARLEAEV----EQLE 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1714 ECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEA--TEKHDNQMNVTEEA 1791
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAelTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1792 TQSIPGETEDQDSLSMSTRPACSESVPSEnSANPAVSEDVSSHDEINnylQQIDQLKERIAGLEEEKQKNKEFSQTLENE 1871
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIE-SLAAEIEELEELIEELE---SELEALLNERASLEEALALLRSELEELSEE 902

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1872 RNALLSQISTKDGELKLLQEEVSKMNL----LNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVT 1947
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELrlegLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1622909128 1948 DAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1990
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1967-2788 1.31e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.87  E-value: 1.31e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1967 VSELEEEKQQLVKEKTKVESEIRKEYL---EKIQGAQKEPGNKSHAKELQELLKEKQQ-EVKQLQKDCIRYQEKISALER 2042
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLiidEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2043 TVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAsfkvllDDTQSEAARVLADNLKLKKELQSNKESVKSQmKQKD 2122
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK------DLGEEEQLRVKEKIGELEAEIASLERSIAEK-EREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2123 EDLERRLEQAEE---KHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAF------- 2192
Cdd:TIGR02169  318 EDAEERLAKLEAeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYreklekl 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2193 TKSMSSLQDDRDRVIDEAKKWE-----------------RKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKIN 2255
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSeeladlnaaiagieakiNELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2256 ISRLEhDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESE-------------------- 2315
Cdd:TIGR02169  478 YDRVE-KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaagnrlnnvvved 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2316 -----------------------LNILKDQLTDLSNSLEK-CKEQKENLEGIIRQQEadiqnSKFSYEQLETDLQASREL 2371
Cdd:TIGR02169  557 davakeaiellkrrkagratflpLNKMRDERRDLSILSEDgVIGFAVDLVEFDPKYE-----PAFKYVFGDTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2372 TSRLHEEINM---------KEQKMI--SLLSGKEEAIQVAIAELRQQHDKEIKELENLLsqeeeenivleeenkkavdkt 2440
Cdd:TIGR02169  632 ARRLMGKYRMvtlegelfeKSGAMTggSRAPRGGILFSRSEPAELQRLRERLEGLKREL--------------------- 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2441 NQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsvilekdqlIQEAAAENNKLKEEIRGLRSH 2520
Cdd:TIGR02169  691 SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER-----------LEELEEDLSSLEQEIENVKSE 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2521 MDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKElknkyakleeKLKESEEANEDLQRSSNALQEEKR 2600
Cdd:TIGR02169  760 LKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEE----------EVSRIEARLREIEQKLNRLTLEKE 829

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2601 DLSKEIESLKVSVSQLTRQVTALQEE-----GTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELvcvqKEAAKKV 2675
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEienlnGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL----RELERKI 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2676 GEIEDKLKKELKHLhhdaGIMRNETETAEERVAELARDLVEMEQKLLMVTKEnKDLTAQIQSFGRSMSSLQNSRDHANEE 2755
Cdd:TIGR02169  906 EELEAQIEKKRKRL----SELKAKLEALEEELSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRALEPVNMLAIQE 980

                          890       900       910
                   ....*....|....*....|....*....|...
gi 1622909128 2756 LDELKRKYDaslkelaQLKEQQGLLNRERHALL 2788
Cdd:TIGR02169  981 YEEVLKRLD-------ELKEKRAKLEEERKAIL 1006
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1589-2416 5.45e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.94  E-value: 5.45e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1589 VKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVS---NEAERIQHVVEAVRQ-EKQELYGKLRSTEANKKETEK 1664
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRrerEKAERYQALLKEKREyEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1665 QLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKF 1744
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1745 QSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKhdnqmnvteeatqsipgetEDQDSLSMSTRPACSESVpsenSAN 1824
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYA-------------------ELKEELEDLRAELEEVDK----EFA 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1825 PAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQ 1904
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLA 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1905 EELSRVTKLKETAEEEKDDLEERLMN---QLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEk 1981
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKlqrELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATA- 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1982 tkveseirkeyLEKIQGAQKEP---GNKSHAKELQELLKEKQ---------QEVKQLQKDcIRYQEKISALERTVKALEF 2049
Cdd:TIGR02169  541 -----------IEVAAGNRLNNvvvEDDAVAKEAIELLKRRKagratflplNKMRDERRD-LSILSEDGVIGFAVDLVEF 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2050 VQTESQKDLEITKENLaqAVEHRKKAQAELASFK-VLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLErR 2128
Cdd:TIGR02169  609 DPKYEPAFKYVFGDTL--VVEDIEAARRLMGKYRmVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLE-G 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2129 LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQvtlnkkdKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2208
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE-------KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2209 EAKKWERKFSDaIQTKEEEIRLKEENC--SVLKDQLRQMSIHMEELKINISRLE----HDKQIWESKAQTEVQLQQKVcD 2282
Cdd:TIGR02169  759 ELKELEARIEE-LEEDLHKLEEALNDLeaRLSHSRIPEIQAELSKLEEEVSRIEarlrEIEQKLNRLTLEKEYLEKEI-Q 836

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2283 TLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLE 2362
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909128 2363 TDLQASRELTSRLHEEINMKEQKMISLLS-GKEEAIQVAIAELRQQHDKEIKELE 2416
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGEDEEiPEEELSLEDVQAELQRVEEEIRALE 971
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 760-1105 8.83e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 8.83e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  760 VVTELRAQVRQLEmnlAEAERQRRFdyesqtahhNLLTEQIHSLSIEAKSKdvKIEVLQNELDDVQLQFSEQSTLIRSLQ 839
Cdd:COG1196    194 ILGELERQLEPLE---RQAEKAERY---------RELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  840 SQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQL 919
Cdd:COG1196    260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  920 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDemspagliskEELQHEFDLLKKENEQRKRKLQA 999
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE----------ELAEELLEALRAAAELAAQLEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1000 ALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSkcQEIEISLKQTISEKEVELEHIR 1079
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL--LELLAELLEEAALLEAALAELL 483

                          330       340
                   ....*....|....*....|....*.
gi 1622909128 1080 KDLEEKMAAEEQLQALVKEMNQTLQD 1105
Cdd:COG1196    484 EELAEAAARLLLLLEAEADYEGFLEG 509
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2009-2609 8.91e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 8.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2009 AKELQELLKEKQQEVKQLQKDciRYQEKISALERTVKALEfvqtesqkdleitkENLAQAVEHRKKAQAELASFKVLLDD 2088
Cdd:COG1196    215 YRELKEELKELEAELLLLKLR--ELEAELEELEAELEELE--------------AELEELEAELAELEAELEELRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2089 TQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV 2166
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERleELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2167 TLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRvideakkwerkfsdaIQTKEEEIRLKEENCSVLKDQLRQMS 2246
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2247 IHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDL 2326
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2327 SNSLE--KCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEInmkEQKMISLLSGKEEAiQVAIAEL 2404
Cdd:COG1196    504 EGFLEgvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEV---AAAAIEYLKAAKAG-RATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2405 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLnaikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQ 2484
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL----LGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2485 LEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDsQQKQLLEAQLQQN 2564
Cdd:COG1196    656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL-EEEALEEQLEAER 734

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1622909128 2565 KELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESL 2609
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1454-2336 1.07e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.17  E-value: 1.07e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1454 ERIKQLQVELCEMKQKPEEIEEEsRAKQQIQRKLQAALISRK--EALKENKSLQEELSLARDTIEHLTKSLADVESHVSA 1531
Cdd:TIGR02169  184 ENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEgyELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1532 QNKEKDRVLGRLALLQEERDKLITEMDRSLLEN-QSLSGSCESLKLALEGLTEDKEKLVKEIESLKSskiaESSEWQEKH 1610
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSIAEKERELEDAEERLAKLEA----EIDKLLAEI 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1611 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQK 1690
Cdd:TIGR02169  339 EELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRL 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1691 ILELEEENDRLRAevhpaggtAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVS 1770
Cdd:TIGR02169  419 SEELADLNAAIAG--------IEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1771 KQANLEATEKHDNQMNVTEEATQSIPGETED------QDSLSMSTRPACSESVPSENSANPAVSEDVSShdeinnylqqi 1844
Cdd:TIGR02169  491 ELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvAQLGSVGERYATAIEVAAGNRLNNVVVEDDAV----------- 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1845 dqLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLqeevskMNLLNQQIQEELSRVTKLKETAEEEKDDL 1924
Cdd:TIGR02169  560 --AKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1925 EERLMNQ--LAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRkeyleKIQGAQKE 2002
Cdd:TIGR02169  632 ARRLMGKyrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELR-----RIENRLDE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2003 PgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASF 2082
Cdd:TIGR02169  707 L--SQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2083 KVLLDDTQSEAARVLADnlKLKKELQSNkESVKSQMKQKDEDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIG 2162
Cdd:TIGR02169  785 EARLSHSRIPEIQAELS--KLEEEVSRI-EARLREIEQKLNRLTLEKEYLE----KEIQELQEQRIDLKEQIKSIEKEIE 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2163 EIQVTLNKKDKEIQQVQenldstvAQLAAFTKSMSSLQDDRDRVIDEAKKWERKfsdaIQTKEEEIRLKEENCSVLKDQL 2242
Cdd:TIGR02169  858 NLNGKKEELEEELEELE-------AALRDLESRLGDLKKERDELEAQLRELERK----IEELEAQIEKKRKRLSELKAKL 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2243 RQMSIHMEELKINISRLEHDKQIWES--KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESElnilK 2320
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPEEELSleDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEE----R 1002

                          890
                   ....*....|....*.
gi 1622909128 2321 DQLTDLSNSLEKCKEQ 2336
Cdd:TIGR02169 1003 KAILERIEEYEKKKRE 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2447-3190 1.20e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 1.20e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2447 LNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSV---ILEKDQLIQEAAAENNKLKEEIRGLRSHMDD 2523
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELeeeIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2524 LNSENAKLDAELIQYREDLNQVISIKDSQQKQL------LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQE 2597
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2598 EKRDLSKEIESLKVSVSQLTRQVTALQEE-----------------GTLGIYHAQLKVKEEELQRLSALLSSSQKRITEL 2660
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2661 EEELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMV 2724
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2725 TKENKDLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSM 2795
Cdd:TIGR02168  554 NLNAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2796 DLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpats 2875
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEEL----------------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2876 LAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQL 2955
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2956 RMEKSSWEIHERRMKEQYLMAisDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRN 3035
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 3036 QLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNI 3115
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRR 915

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128 3116 DvapgapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSLAEEQIRRLE 3190
Cdd:TIGR02168  916 E-------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1497-2090 1.31e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.40  E-value: 1.31e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1497 ALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMD---RSLLENQSLSGSCES 1573
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1574 LKLALEGLTEDKEKL---VKEIESLKSSKIAESSEWQEKHKELQ------KEYEIL---LQSYENVSNEAERIQHVVEAV 1641
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLsefYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1642 RQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskqQKILELEEENDRLRAEVhpaGGTAKECMETLLS 1721
Cdd:PRK03918   323 INGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY-----EEAKAKKEELERLKKRL---TGLTPEKLEKELE 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1722 SNASMKEEVERvkmEYETLSKKFQSLMSEKDSLSEEVQDLKHQleSNVSKQANLEATEKHdnQMNVTEEATQSIPGETED 1801
Cdd:PRK03918   395 ELEKAKEEIEE---EISKITARIGELKKEIKELKKAIEELKKA--KGKCPVCGRELTEEH--RKELLEEYTAELKRIEKE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1802 QDSLSMSTRPACSESVPSENSANPavSEDVSSHDEInnyLQQIDQLKERIAG--LEEEKQKNKEFSQTLEnernallsQI 1879
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKK--ESELIKLKEL---AEQLKELEEKLKKynLEELEKKAEEYEKLKE--------KL 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1880 STKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLESE 1959
Cdd:PRK03918   535 IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYNE 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1960 MKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKIS 2038
Cdd:PRK03918   604 YLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSRELA 676

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622909128 2039 ALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2090
Cdd:PRK03918   677 GLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 758-1489 1.37e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.79  E-value: 1.37e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  758 LSVVTELRAQVRQLEMNLAEAERQ------RRFDYESQTAHHNLLTEQIhSLSIEAKSKDVKIEVlQNELDDVQLQFSEQ 831
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEEleklteEISELEKRLEEIEQLLEEL-NKKIKDLGEEEQLRV-KEKIGELEAEIASL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  832 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEisfs 911
Cdd:TIGR02169  307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE---- 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  912 MTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQnydemspagliSKEELQHEFDLLKKENE 991
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA-----------KINELEEEKEDKALEIK 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  992 QRKRKLQAALINRKELLQRVSRLEEELANLKD---QSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTI 1068
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKelsKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1069 SEKEvelehiRKDLEEKMAAEEQLQALVKEMNQTLQ-------------------DKTNQIDLLQAEISENQVIIQKLTT 1129
Cdd:TIGR02169  532 SVGE------RYATAIEVAAGNRLNNVVVEDDAVAKeaiellkrrkagratflplNKMRDERRDLSILSEDGVIGFAVDL 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1130 SNTDASDGDSVALV-KETVVIS-----------------------PPGT--------DSGEHWKPELEEKILALEKEKEQ 1177
Cdd:TIGR02169  606 VEFDPKYEPAFKYVfGDTLVVEdieaarrlmgkyrmvtlegelfeKSGAmtggsrapRGGILFSRSEPAELQRLRERLEG 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1178 LQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKlpsPDQQE 1257
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK---SELKE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1258 WCSPTPGLEEPLFKATEQhhtqpvlesnlcpdwpshSEDASALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKK 1337
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEA------------------LNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRL 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1338 SEEVFQLQDqinkqglEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE-HLRELQPELDELQKLISEKEEDVSYLSGQ 1416
Cdd:TIGR02169  825 TLEKEYLEK-------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQ 897

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622909128 1417 LREKEAALTKIQTEIIEQEDLIKALHTQLEMQAkehdERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQA 1489
Cdd:TIGR02169  898 LRELERKIEELEAQIEKKRKRLSELKAKLEALE----EELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 685-1239 2.14e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 2.14e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  685 QDELERLKSQILELElnfhKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKelsvvtEL 764
Cdd:COG1196    238 EAELEELEAELEELE----AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------RL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  765 RAQVRQLEMNLAEAERQRrfdyESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN 844
Cdd:COG1196    308 EERRRELEERLEELEEEL----AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  845 KESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKF 924
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  925 SLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEF-------------DLLKKENE 991
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrglagavavligVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  992 QRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEK 1071
Cdd:COG1196    540 LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1072 EVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKEtvvisp 1151
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL------ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1152 pgtdsgehwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1231
Cdd:COG1196    694 -----------ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762


                   ....*...
gi 1622909128 1232 GDQLRQLQ 1239
Cdd:COG1196    763 EELERELE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2222-2773 2.24e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 2.24e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2222 QTKEEEIRLKEENCSVLKDQLRQMSIhmEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2301
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2302 YHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2381
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2382 KEQKMISLLSgKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQL 2461
Cdd:COG1196    370 AEAELAEAEE-ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2462 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAEN------------------NKLKEEIRGLRSHMDD 2523
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLllleaeadyegflegvkaALLLAGLRGLAGAVAV 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2524 LNSENAKLDAELIQYREDLNQVISIKDSQQ-KQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDL 2602
Cdd:COG1196    529 LIGVEAAYEAALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2603 SKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKL 2682
Cdd:COG1196    609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2683 KKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRK 2762
Cdd:COG1196    689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768

                          570
                   ....*....|.
gi 1622909128 2763 YDASLKELAQL 2773
Cdd:COG1196    769 LERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2053-2664 3.78e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 3.78e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2053 ESQKDLEITKENLAQA----VEHRK-----KAQAELAsfkvllddtqsEAARVLADNLKLKK-ELQSNKESVKSQMKQKD 2122
Cdd:COG1196    176 EAERKLEATEENLERLedilGELERqleplERQAEKA-----------ERYRELKEELKELEaELLLLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2123 EDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAftksmssLQDD 2202
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE-------LEER 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2203 RDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2282
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2283 TLQgENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLE 2362
Cdd:COG1196    398 LAA-QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2363 TDLQASRELTSRLHEEINMKEQkMISLLSGKEEA------------IQVAIAELRQQHDKEIKELENLLSQEEEENIVLE 2430
Cdd:COG1196    477 AALAELLEELAEAAARLLLLLE-AEADYEGFLEGvkaalllaglrgLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2431 EENKKAV---DKTNQLM----ETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEA 2503
Cdd:COG1196    556 DEVAAAAieyLKAAKAGratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2504 AAENNKLKEEIRGLRSHMDDLNSENAKldaeliqyredlnqvISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEE 2583
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSL---------------TGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2584 ANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRlsallSSSQKRITELEEE 2663
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-----EELERELERLERE 775


                   .
gi 1622909128 2664 L 2664
Cdd:COG1196    776 I 776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2172-2943 4.23e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 4.23e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2172 DKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERkfSDAIQTKEEEIRLKEencsvLKDQLRQMSIHMEE 2251
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYE-----LLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2252 LKINISRLEhdkqiwESKAQTEVQLQQKVCDTlqGENKELLSQLEEtrHLYHNSQNELAKLESELNILKDQLTDLSNSLE 2331
Cdd:TIGR02169  242 IERQLASLE------EELEKLTEEISELEKRL--EEIEQLLEELNK--KIKDLGEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2332 KCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSgKEEAIQVAIAELRQQHDKE 2411
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA-ELEEVDKEFAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2412 IKELENL-----------------LSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQND 2474
Cdd:TIGR02169  391 REKLEKLkreinelkreldrlqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2475 RDRIVGDYQQLEERhlsvILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENA---KLDAELIQYRED---------- 2541
Cdd:TIGR02169  471 LYDLKEEYDRVEKE----LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaag 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2542 --LNQVISIKDSQQKQLLEAQLQQNK----------------------------------ELKNKYAKLEEKLKESEEAN 2585
Cdd:TIGR02169  547 nrLNNVVVEDDAVAKEAIELLKRRKAgratflplnkmrderrdlsilsedgvigfavdlvEFDPKYEPAFKYVFGDTLVV 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2586 EDLQrSSNALQEEKRDLSKEIESLKVS-------VSQLTRQVTALQEEGTLgiyhAQLKVKEEELQRLSALLSSSQKRIT 2658
Cdd:TIGR02169  627 EDIE-AARRLMGKYRMVTLEGELFEKSgamtggsRAPRGGILFSRSEPAEL----QRLRERLEGLKRELSSLQSELRRIE 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2659 ELEEELVCVQKEAAKKVGEIEDklkkelkhlhhDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSF 2738
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEK-----------EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2739 GRSMSSLQnsrdhanEELDELKRKYDASlkelaQLKEQQGLlnrerhallsettfsmdlpeenslsyLEKLNQQLLSKDE 2818
Cdd:TIGR02169  771 EEDLHKLE-------EALNDLEARLSHS-----RIPEIQAE--------------------------LSKLEEEVSRIEA 812

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2819 QLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQ----SLKKAMSSLQNDRD 2894
Cdd:TIGR02169  813 RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEaalrDLESRLGDLKKERD 892

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1622909128 2895 RLLKELKNLQQQYLQINQEITELRPLKAQLQEyqdktkTFQIMQEELRQ 2943
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKKRKRLSELKA------KLEALEEELSE 935
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1386-2297 4.41e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 4.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1386 LEHLRELQPELDELQKLISEKEEDVSYLSGQlREKEAALTKIQTEIIEQEDLIKALhtqlemQAKEHDERIKQLQVELCE 1465
Cdd:TIGR02169  176 LEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLK------EKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1466 MKQKPEEIEEEsraKQQIQRKLQAALISRKEALKENKSLQEELSLA-RDTIEHLTKSLADVESHVSAQNKEKDRVLGRLA 1544
Cdd:TIGR02169  249 LEEELEKLTEE---ISELEKRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1545 LLQEERDKLITEMdrsllenqslsgsceslklalegltedkEKLVKEIESLKSSKIAesseWQEKHKELQKEYEILLQSY 1624
Cdd:TIGR02169  326 KLEAEIDKLLAEI----------------------------EELEREIEEERKRRDK----LTEEYAELKEELEDLRAEL 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1625 ENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANkketEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1704
Cdd:TIGR02169  374 EEVDKEFAETRDELKDYREKLEKLKREINELKRE----LDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1705 VhpaggtakECMETLLSSNASMKEEVERvkmEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKhdnq 1784
Cdd:TIGR02169  450 I--------KKQEWKLEQLAADLSKYEQ---ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEE---- 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1785 mnVTEEATQSIPGETEDQDSLSMSTRPACsESVPSENSANPAVSEDVSShdeinnylqqidqlKERIAGLEEEKQKNKEF 1864
Cdd:TIGR02169  515 --VLKASIQGVHGTVAQLGSVGERYATAI-EVAAGNRLNNVVVEDDAVA--------------KEAIELLKRRKAGRATF 577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1865 SQTLENERNALLSQISTKDGELKLLqeevskMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQ--LAELNGSIGNY 1942
Cdd:TIGR02169  578 LPLNKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKyrMVTLEGELFEK 651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1943 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEylekiqgaqkepgnKSHAKELQELLKEKQQE 2022
Cdd:TIGR02169  652 SGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI--------------ENRLDELSQELSDASRK 717

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2023 VKQLQKDciryqekISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASfkvllddtqseaarvladnlk 2102
Cdd:TIGR02169  718 IGEIEKE-------IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEE--------------------- 769

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2103 lkkelqsnKESVKSQMKQKDEDLERRLEQaeekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2182
Cdd:TIGR02169  770 --------LEEDLHKLEEALNDLEARLSH------SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI 835

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2183 DSTVAQLAAFTKSMSSLQDDrdrvIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHD 2262
Cdd:TIGR02169  836 QELQEQRIDLKEQIKSIEKE----IENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1622909128 2263 KQIWESK-AQTEVQLQqkvcdTLQGENKELLSQLEE 2297
Cdd:TIGR02169  912 IEKKRKRlSELKAKLE-----ALEEELSEIEDPKGE 942
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1306-1779 4.99e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 4.99e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1306 VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAG 1385
Cdd:COG1196    283 LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1386 LEH-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELC 1464
Cdd:COG1196    363 AEEaLLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1465 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSA-----QNKEKDRV 1539
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkaalLLAGLRGL 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1540 LGRLALLQEERDKLITEmDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEI 1619
Cdd:COG1196    523 AGAVAVLIGVEAAYEAA-LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1620 LLQSYENVsnEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEEND 1699
Cdd:COG1196    602 DLVASDLR--EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1700 RLRAEVhpaggtakecmETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATE 1779
Cdd:COG1196    680 ELEELA-----------ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 687-1133 5.51e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 5.51e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  687 ELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKElsvvtelra 766
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHK--------- 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  767 qvRQLEMNLAEAERQRRFDYESQTAhhnllteqihslsieakskdVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKE 846
Cdd:pfam15921  389 --REKELSLEKEQNKRLWDRDTGNS--------------------ITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  847 SEVL-------EGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQL 919
Cdd:pfam15921  447 ERQMaaiqgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSR 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  920 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMS--------PAGLISKEELQ----------- 980
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTqlvgqhgrTAGAMQVEKAQlekeindrrle 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  981 -HEFDLLKKENEQRKRKLQAALINRK-ELLQRVSRLEEELANLKDQSKKEIPL---SESERGEVEEDKENKEYSEKCVTS 1055
Cdd:pfam15921  606 lQEFKILKDKKDAKIRELEARVSDLElEKVKLVNAGSERLRAVKDIKQERDQLlneVKTSRNELNSLSEDYEVLKRNFRN 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1056 KCQEIEIS---LKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEIsenQVIIQKLTTSNT 1132
Cdd:pfam15921  686 KSEEMETTtnkLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI---QFLEEAMTNANK 762


                   .
gi 1622909128 1133 D 1133
Cdd:pfam15921  763 E 763
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1991-2860 5.58e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.47  E-value: 5.58e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1991 EYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKD---CIRYQEKISALErtvkalEFVQTESQKDLEITKENLA 2066
Cdd:TIGR02169  167 EFDRKKEKALEELEEvEENIERLDLIIDEKRQQLERLRRErekAERYQALLKEKR------EYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2067 QAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKhLKEKKNMQEK 2146
Cdd:TIGR02169  241 AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERS-IAEKERELED 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2147 LDALRREkvhLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEE 2226
Cdd:TIGR02169  320 AEERLAK---LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2227 EIRLKEE---NCSVLKDQLRQMSIHMEELKINISRLEhdKQIWESKAQTEvqlqqkvcdTLQGENKELLSQLEETRHLYH 2303
Cdd:TIGR02169  397 LKREINElkrELDRLQEELQRLSEELADLNAAIAGIE--AKINELEEEKE---------DKALEIKKQEWKLEQLAADLS 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2304 NSQNELAKLESELNILKDQLTDLSNSLEKCKEQKenlegiiRQQEADIQNSKFSYEQLETDLQASRELTSRLheeINMKE 2383
Cdd:TIGR02169  466 KYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA-------RASEERVRGGRAVEEVLKASIQGVHGTVAQL---GSVGE 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2384 QKMISL---LSGKEEAIQV--------AIAELRQQHD--------KEIKELENLLSQEEEENIVLEEENKKAVDKTNQ-- 2442
Cdd:TIGR02169  536 RYATAIevaAGNRLNNVVVeddavakeAIELLKRRKAgratflplNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEpa 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2443 ---------LMETLNAIKKENIQQKA---QLDSFVKS--MSSLQNDRDRIVGDYQQLEERHLSVILEKDQLiqeaAAENN 2508
Cdd:TIGR02169  616 fkyvfgdtlVVEDIEAARRLMGKYRMvtlEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGL----KRELS 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2509 KLKEEIRGLRSHMDdlnsenakldaELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLeeklkeseeanEDL 2588
Cdd:TIGR02169  692 SLQSELRRIENRLD-----------ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL-----------SSL 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2589 QRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQ 2668
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEAR----LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLT 825

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2669 KEAakkvgEIEDKLKKELKHLHHDAGIMRNETETAEE----RVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSS 2744
Cdd:TIGR02169  826 LEK-----EYLEKEIQELQEQRIDLKEQIKSIEKEIEnlngKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2745 LQNsrdhaneELDELKRKYDASLKELAQLKEQQGLLNRERHALlsETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLS 2824
Cdd:TIGR02169  901 LER-------KIEELEAQIEKKRKRLSELKAKLEALEEELSEI--EDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALE 971

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|...
gi 1622909128 2825 S-------QLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRK 2860
Cdd:TIGR02169  972 PvnmlaiqEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2365-3189 9.85e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 9.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2365 LQASRELTSRLHEEINMKEQKMISLLSG-------KEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAV 2437
Cdd:TIGR02168  205 LERQAEKAERYKELKAELRELELALLVLrleelreELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIE 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2438 DKTNQLMETLNAIKKENiQQKAQLDsfvKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQL---IQEAAAENNKLKEEI 2514
Cdd:TIGR02168  285 ELQKELYALANEISRLE-QQKQILR---ERLANLERQLEELEAQLEELESKLDELAEELAELeekLEELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2515 RGLRSHMDDLNSENAKLDAELIQYREDLNQVisikdSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDlQRSSNA 2594
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSKVAQL-----ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK-KLEEAE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2595 LQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyHAQLKVKEEELQRLSALLSSSQKRITELEEelvcvQKEAAKK 2674
Cdd:TIGR02168  435 LKELQAELEELEEELEELQEELERLEEALEEL------REELEEAEQALDAAERELAQLQARLDSLER-----LQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2675 VGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQ---SFGRSMSSLQNSRDH 2751
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLkqnELGRVTFLPLDSIKG 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2752 A-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLSS 2825
Cdd:TIGR02168  584 TeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGG 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2826 QLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpatsLAEVQSLKKAMSSLQNDRDRLLKELKNLQQ 2905
Cdd:TIGR02168  660 VI---TGGSAKTNSSILERRREIEELEEKIEEL-----------------EEKIAELEKALAELRKELEELEEELEQLRK 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2906 QYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAisDKDQQVS 2985
Cdd:TIGR02168  720 ELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA--QIEQLKE 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2986 HLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEK 3065
Cdd:TIGR02168  797 ELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 3066 NTLSIQLcdtsqslrenqqhygdllnhcAVLEKQVQELQavskekgplnidvapgapqekngvhrksdpEELREPQQSFS 3145
Cdd:TIGR02168  869 EELESEL---------------------EALLNERASLE------------------------------EALALLRSELE 897

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1622909128 3146 EAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSLAEEQIRRL 3189
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1417-1936 1.03e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 64.68  E-value: 1.03e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1417 LREKEAALTKIQTEI--IEQEDLIKALHTqLEMQAKEHDERIKQLQVE---LCEMKQKPEEIEEESRAKQQIQRKLQAAL 1491
Cdd:PRK02224   182 LSDQRGSLDQLKAQIeeKEEKDLHERLNG-LESELAELDEEIERYEEQreqARETRDEADEVLEEHEERREELETLEAEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1492 ----ISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSL 1567
Cdd:PRK02224   261 edlrETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1568 SGSCESLK---LALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQE 1644
Cdd:PRK02224   341 NEEAESLRedaDDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1645 KQELYGKLRSTEANKKETEKQLQEAEKEMEE----------MKEKMRKFAKSKQQKILELEEENDRLRAEVhpaggtake 1714
Cdd:PRK02224   421 RDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEV--------- 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1715 cmetllssnASMKEEVERVKMEYETlSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANL-EATEKHDNQMNVTEEATQ 1793
Cdd:PRK02224   492 ---------EEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRETIEEKRERAEELrERAAELEAEAEEKREAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1794 SIPGETEDqdslSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEekqknkefsqtLENERN 1873
Cdd:PRK02224   562 EAEEEAEE----AREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAE-----------LNDERR 626

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909128 1874 ALLSQISTKDGEL--KLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER---LMNQLAELN 1936
Cdd:PRK02224   627 ERLAEKRERKRELeaEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELE 694
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1070-1926 1.04e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 1.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1070 EKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDAsDGDSVALVKEtvvi 1149
Cdd:TIGR02168  222 LRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL-QKELYALANE---- 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1150 sppgtdsgehwKPELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENE 1229
Cdd:TIGR02168  297 -----------ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1230 NIGDQLRQLQIQVREsidgklpspDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsEDASALQGGTSVAQI 1309
Cdd:TIGR02168  362 ELEAELEELESRLEE---------LEEQLETLRSKVAQLELQIASLNNEIERLEARL--------ERLEDRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1310 KAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQlqiAGLEHL 1389
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE---RLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1390 RELQPELDELQKLISEKEEDVSYLSGQLR---EKEAALtkiqtEIIEQEDLIKALHTQLE--MQAKEHDERIKQLQVELC 1464
Cdd:TIGR02168  502 EGFSEGVKALLKNQSGLSGILGVLSELISvdeGYEAAI-----EAALGGRLQAVVVENLNaaKKAIAFLKQNELGRVTFL 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1465 EMKQKPEeieeesrakQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKD-RVLGRL 1543
Cdd:TIGR02168  577 PLDSIKG---------TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKlRPGYRI 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1544 ALLQEE---RDKLIT----EMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKE 1616
Cdd:TIGR02168  648 VTLDGDlvrPGGVITggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1617 YEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEE 1696
Cdd:TIGR02168  728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1697 ENDRLRAevhpaggtakecmetLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLE 1776
Cdd:TIGR02168  808 LRAELTL---------------LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1777 -ATEKHDNQMNVTEEATQSIpgeTEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAgle 1855
Cdd:TIGR02168  873 sELEALLNERASLEEALALL---RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS--- 946

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909128 1856 EEKQKNKEFSQTLENERNALLSQIstkDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEE 1926
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2483-3054 1.57e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 1.57e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2483 QQLEERHLSVILEKDQLIQEAAAEnnkLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQvisikdsqQKQLLEAQLQ 2562
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEE---LEAELEELEAELEELEAELAELEAELEELRLELEE--------LELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2563 QNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKEEE 2642
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE--LEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2643 LQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDkLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLL 2722
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2723 MVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQgllnRERHALLSETTFSMDLPEENS 2802
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE----ADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2803 LSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSL 2882
Cdd:COG1196    522 LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2883 KKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTK------TFQIMQEELRQENLSWQHELHQLR 2956
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLegeggsAGGSLTGGSRRELLAALLEAEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2957 MEKSSWEIHERRMKEQYLMAISDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASPETSASPDGSQNLIYETELLRNQ 3036
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                          570
                   ....*....|....*...
gi 1622909128 3037 LNDSLKEIHQKELRIQQL 3054
Cdd:COG1196    762 LEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 48-927 2.00e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.92  E-value: 2.00e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128   48 EDVQERLAYAEQLVVELKDIIRQKDVQLqqkdEALQEEKKAADNKIKKLKLHAKAKLTSLNKHIEEMKAQGGTVLLTEPQ 127
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQL----KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  128 SEEQLSKHDKSSTEEEMEVEKIKHKLQEKEEQIstlqaqltqaqAEQAAQFDKSSTEMKEFVMMKQQLQEKEELISTLQA 207
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEI-----------EELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  208 QLSQTQAEQAAQvvREKDARFETQVRLHEDELLQLVTQADVE-TEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTA 286
Cdd:TIGR02168  320 ELEAQLEELESK--LDELAEELAELEEKLEELKEELESLEAElEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  287 AEQRNQILSQQLQQIEAEHNTLRNTVETEREE-SKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQAELESRY 365
Cdd:TIGR02168  398 LNNEIERLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  366 SALEQKHKAEMEEKTShILSLQKTGQELQSACDALKDQNSKLLQD------------KDEQAVQSA--QTIEQLEDQLQQ 431
Cdd:TIGR02168  478 DAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGIlgvlselisvdeGYEAAIEAAlgGRLQAVVVENLN 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  432 KSKEISQFlnrlpLQQHETASQTCFPdvynegtqaVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQI- 510
Cdd:TIGR02168  557 AAKKAIAF-----LKQNELGRVTFLP---------LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLl 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  511 -------TLLEAQNRIGEADREVSEISIVDD-ANKRSSSTEESGQDVLeNTFSQKhKELSVLLLEMKEAQEEIAFLKLQL 582
Cdd:TIGR02168  623 ggvlvvdDLDNALELAKKLRPGYRIVTLDGDlVRPGGVITGGSAKTNS-SILERR-REIEELEEKIEELEEKIAELEKAL 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  583 QgkRAEEGDHEVLDQKEMKQMEGEGIapikmevfledtgqnfplmpNEESSLPAVEKEQASTEHQNRTSEEISLndagve 662
Cdd:TIGR02168  701 A--ELRKELEELEEELEQLRKELEEL--------------------SRQISALRKDLARLEAEVEQLEERIAQL------ 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  663 lkstkqdcdkslsavpdigqchQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNSSAFT 742
Cdd:TIGR02168  753 ----------------------SKELTELEAEIEELEERLEEAEE----ELAEAEAEIEELEAQIEQLKEELKALREALD 806

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  743 ALSEERDQLLAQvkelsvVTELRAQVRQLEMNLAEAERQRRfDYESQTAHhnlLTEQIHSLSIEAKSKDVKIEVLQNELD 822
Cdd:TIGR02168  807 ELRAELTLLNEE------AANLRERLESLERRIAATERRLE-DLEEQIEE---LSEDIESLAAEIEELEELIEELESELE 876

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  823 DVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKR----DVETLQQTI 898
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLTLEEA 956

                          890       900
                   ....*....|....*....|....*....
gi 1622909128  899 EEKDQQVTEISFSMTEKMVQLNEEKFSLG 927
Cdd:TIGR02168  957 EALENKIEDDEEEARRRLKRLENKIKELG 985
PTZ00121 PTZ00121
MAEBL; Provisional
 1905-2530 2.20e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 2.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1905 EELSRVTKLKETAEEEKDDLEER---LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE--EEKQQLVK 1979
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERnneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKkaEEKKKADE 1306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1980 EKTKVESEIRKEYLEKiqgaqKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLE 2059
Cdd:PTZ00121  1307 AKKKAEEAKKADEAKK-----KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD 1381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2060 ITK---ENLAQAVEHRKKAQAELASFKVLlddTQSEAARVLADNLKLKKELQSNKESVK--SQMKQKDEDLERRLEQAEE 2134
Cdd:PTZ00121  1382 AAKkkaEEKKKADEAKKKAEEDKKKADEL---KKAAAAKKKADEAKKKAEEKKKADEAKkkAEEAKKADEAKKKAEEAKK 1458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2135 -KHLKEKKNMQEKLDALRR---EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQD-DRDRVIDE 2209
Cdd:PTZ00121  1459 aEEAKKKAEEAKKADEAKKkaeEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaEEAKKADE 1538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2210 AKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENK 2289
Cdd:PTZ00121  1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2290 ----ELLSQLEETRHLYHNSQN----------ELAKLESELNILKDQLTdlsnslEKCKEQKENLEGIiRQQEADIQNSK 2355
Cdd:PTZ00121  1619 kikaEELKKAEEEKKKVEQLKKkeaeekkkaeELKKAEEENKIKAAEEA------KKAEEDKKKAEEA-KKAEEDEKKAA 1691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2356 FSYEQLETDLQASRELTSRLHEEINMKEQkmislLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKK 2435
Cdd:PTZ00121  1692 EALKKEAEEAKKAEELKKKEAEEKKKAEE-----LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2436 AVDKTNQLMETLNAIK----KENIQQKAQLDSFVKSMSSL-------QNDRDRIVGDYQQLEerhlsvilekDQLIQEAA 2504
Cdd:PTZ00121  1767 EKKAEEIRKEKEAVIEeeldEEDEKRRMEVDKKIKDIFDNfaniiegGKEGNLVINDSKEME----------DSAIKEVA 1836

                          650       660
                   ....*....|....*....|....*.
gi 1622909128 2505 AENNKLKEEIRGLRSHMDDLNSENAK 2530
Cdd:PTZ00121  1837 DSKNMQLEEADAFEKHKFNKNNENGE 1862
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1844-2626 2.99e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 2.99e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1844 IDQLKERIAGLEEEKQKNKEFSQTLE-----------NERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTK 1912
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKekreyegyellKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1913 LKETAEEEKDDLEERLMNQLaelngsignycqdvtdaQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEy 1992
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1993 lekiqgaqkepgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKENLAQAVEHR 2072
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD-------KEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2073 KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKsQMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRR 2152
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWK----LEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2153 EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRV---IDEAKKWERKFSDAIQT------ 2223
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVaagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2224 -----------KEEEIRLKEENCS--------VLKDQLRQMSIHMEE--LKINISRLEHDKQ-------------IWESK 2269
Cdd:TIGR02169  550 nnvvveddavaKEAIELLKRRKAGratflplnKMRDERRDLSILSEDgvIGFAVDLVEFDPKyepafkyvfgdtlVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2270 AQTEVQLQQKVCDTLQGENKE----LLSQLEETRHLYHNSQNELAKLESelniLKDQLTDLSNSLEKCKEQKENLEGIIR 2345
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEksgaMTGGSRAPRGGILFSRSEPAELQR----LRERLEGLKRELSSLQSELRRIENRLD 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2346 QQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKmislLSGKEEAIQVAIAELrQQHDKEIKELEnllsqeeee 2425
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED----LSSLEQEIENVKSEL-KELEARIEELE--------- 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2426 nivleeenkkavDKTNQLMETLNAIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQL---IQE 2502
Cdd:TIGR02169  772 ------------EDLHKLEEALNDLEARLSHS--RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2503 AAAENNKLKEEIRGLRSHMDDLNSENAKLDAELiqyredlnqvisikdsqqkqlleaqlqqnKELKNKYAKLEEKLKESE 2582
Cdd:TIGR02169  838 LQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL-----------------------------EELEAALRDLESRLGDLK 888

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1622909128 2583 EANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEE 2626
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1842-2048 3.56e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 61.70  E-value: 3.56e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1842 QQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEK 1921
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1922 DDLEERLMNQLAEL--NGSIGNY-----CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEiRKEYLE 1994
Cdd:COG4942    100 EAQKEELAELLRALyrLGRQPPLalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE-RAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622909128 1995 KIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALE 2048
Cdd:COG4942    179 LLAELEEE------RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1835-2609 3.56e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 3.56e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1835 DEINNYLQQIDQLKERIAGLEEEKQKN-KEFSQTLENERNALLSQISTKDGELKLLQEEVSKmnlLNQQIQEELSRVTKL 1913
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAK---LEAEIDKLLAEIEEL 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1914 KETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYL 1993
Cdd:TIGR02169  342 EREIEEERKRRDK-LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1994 EKIQGAQKEPGNKSHAKELQELLKEKQQEVK-------QLQKDCIRYQEKISALERTVKALEFVQTESQKDLEItKENLA 2066
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEEEKEDKALEIKkqewkleQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE-AEAQA 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2067 QAVEHRkkaQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ----KDEDL---------ERRLEQAE 2133
Cdd:TIGR02169  500 RASEER---VRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvvEDDAVakeaiellkRRKAGRAT 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2134 EKHLKEKKNMQEKLDALRREKVHleetigEIQVTLNKKDKEIQQVqenldstVAQLAAFTKSMSSLQDDRDRVID----- 2208
Cdd:TIGR02169  577 FLPLNKMRDERRDLSILSEDGVI------GFAVDLVEFDPKYEPA-------FKYVFGDTLVVEDIEAARRLMGKyrmvt 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2209 -EAKKWERkfSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWES---KAQTEVQLQQKVCDTL 2284
Cdd:TIGR02169  644 lEGELFEK--SGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENrldELSQELSDASRKIGEI 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2285 QGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFsyEQLETD 2364
Cdd:TIGR02169  722 EKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRI--PEIQAE 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2365 LQASRELTSRLHEEINMKEQKMISLLSGKEEAiqvaiaelrqqhDKEIKELENLLsqeeEENIVLEEENKKAVDKTNQLM 2444
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYL------------EKEIQELQEQR----IDLKEQIKSIEKEIENLNGKK 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2445 ETLNAIKKENIQQKAQLDsfvKSMSSLQNDRDRIVGDYQQLEERhlsvilekdqlIQEAAAENNKLKEEIRGLRSHMDDL 2524
Cdd:TIGR02169  864 EELEEELEELEAALRDLE---SRLGDLKKERDELEAQLRELERK-----------IEELEAQIEKKRKRLSELKAKLEAL 929

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2525 NSENAKLDAELIQYREDLNQVISIKDSQQK-QLLEAQLQQNKELKNKyakLEEKLKESEEANEDLQRSSNALQEEKRDLS 2603
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIPEEELSLEDVQAElQRVEEEIRALEPVNML---AIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006


                   ....*.
gi 1622909128 2604 KEIESL 2609
Cdd:TIGR02169 1007 ERIEEY 1012
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 63-611 5.09e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 5.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128   63 ELKDIIRQKDVQLQ-QKDEALQEEKKAADNKIKKLKLHAKAKLTSLNkHIEEMKAQGGTVLLTEPQSEEQLSKHDKSSTE 141
Cdd:COG1196    217 ELKEELKELEAELLlLKLRELEAELEELEAELEELEAELEELEAELA-ELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  142 EEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEfvmMKQQLQEKEELISTLQAQLSQtQAEQAAQVV 221
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE---LEEELEEAEEELEEAEAELAE-AEEALLEAE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  222 REKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESlvgRAQVVDLLQQELTAAEQRNQILSQQLQQI 301
Cdd:COG1196    372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL---EEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  302 EAEHNTLRNTVETEREESKILLEKMELEVAERKLsfhNLQEEMRHLLEQLEQAGQAQAELESRySALEQKHKAEMEEKTS 381
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAEL---LEELAEAAARLLLLLEAEADYEGFLE-GVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  382 HILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAqtIEQLEDQ---------LQQKSKEISQFLNRLPLQQHETAS 452
Cdd:COG1196    525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA--IEYLKAAkagratflpLDKIRARAALAAALARGAIGAAVD 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  453 QTCFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRIGEADREVSEISIV 532
Cdd:COG1196    603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909128  533 DDANKRSSSTEESGQDVLENtfSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEGDHEVLDQKEMKQMEGEGIAPI 611
Cdd:COG1196    683 ELAERLAEEELELEEALLAE--EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP 759
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 914-1765 5.53e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 5.53e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  914 EKMVQLNEEKFSLGVEIKTLKEQ-LNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagLISKEELQHEFDLLKKENEQ 992
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQeLKLKEQAKKALEYYQLKEKLELEEEYLLYLDY----LKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  993 RKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKE 1072
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1073 VELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPP 1152
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1153 G-TDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1231
Cdd:pfam02463  412 ElARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLS 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1232 GDQLRQLQIQVRESIDG--KLPSPDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDA-----SALQGGT 1304
Cdd:pfam02463  492 RQKLEERSQKESKARSGlkVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEveerqKLVRALT 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1305 SVAQIKAQLKEIETEKEKLELKISSTTSELT--------KKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKL 1376
Cdd:pfam02463  572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPIlnlaqldkATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1377 ESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERI 1456
Cdd:pfam02463  652 VSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQ 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1457 KQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEK 1536
Cdd:pfam02463  732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1537 DRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKE 1616
Cdd:pfam02463  812 EEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESK 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1617 YEillqsyenvsneaeriqhvvEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEE 1696
Cdd:pfam02463  892 EE--------------------KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKE 951

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909128 1697 ENDRLRAEVHPAGGTAKEcmETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQL 1765
Cdd:pfam02463  952 ENNKEEEEERNKRLLLAK--EELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 929-1529 6.96e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 6.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  929 EIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSpaglISKEELQHEFDLLKKENEQRKRKLQAALINRKELL 1008
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELE----LELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1009 QRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEysekcvtskcQEIEISLKQTISEKEVELEHIRKDLEEKMAA 1088
Cdd:COG1196    316 ERLEELEEELAELEEELEEL----EEELEELEEELEEAE----------EELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1089 EEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKEtvvisppgtdsgehwkpELEEKI 1168
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE-----------------EEEEAL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1169 LALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1248
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1249 klpspdqqewcsptPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASalqggtsvAQIKAQLKEIETEKEKLELKIS 1328
Cdd:COG1196    525 --------------AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAA--------AAIEYLKAAKAGRATFLPLDKI 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1329 STTSELTKKSEEVFQLQDQINKQGLEIEslktASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEE 1408
Cdd:COG1196    583 RARAALAAALARGAIGAAVDLVASDLRE----ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1409 DVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelcemkqkpEEIEEESRAKQQIQRKLQ 1488
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA----------EAEEERLEEELEEEALEE 728

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1622909128 1489 AALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHV 1529
Cdd:COG1196    729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2304-2775 8.24e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.57  E-value: 8.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2304 NSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE--EINM 2381
Cdd:TIGR04523  149 KKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISElkKQNN 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2382 KEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQL 2461
Cdd:TIGR04523  229 QLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDW 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2462 DSFVKSmsSLQNDRDRIVGDYQQLEERHLSVilekdqliqeaaaenNKLKEEIRGLRSHMDDLNSENAKLDAELiqyRED 2541
Cdd:TIGR04523  309 NKELKS--ELKNQEKKLEEIQNQISQNNKII---------------SQLNEQISQLKKELTNSESENSEKQREL---EEK 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2542 LNQVISIKDSQQKQLleaqlQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVT 2621
Cdd:TIGR04523  369 QNEIEKLKKENQSYK-----QEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIK 443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2622 ALQEEGTlgiyhaqlkVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETE 2701
Cdd:TIGR04523  444 DLTNQDS---------VKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK-EKELKKLNEEKKELEEKVK 513

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128 2702 TAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQS--FGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2775
Cdd:TIGR04523  514 DLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQE 589
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1163-1761 1.13e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1163 ELEEKILALEKEKEQLQKKLQEALTSrkaiLKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQV 1242
Cdd:COG1196    271 ELRLELEELELELEEAQAEEYELLAE----LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1243 REsidgklpspdqqewcsptpglEEPLFKATEQHHTQpvlesnlcpdwpshsEDASALQGGTSVAQIKAQLKEIETEKEK 1322
Cdd:COG1196    347 EE---------------------AEEELEEAEAELAE---------------AEEALLEAEAELAEAEEELEELAEELLE 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1323 LELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAglEHLRELQPELDELQKL 1402
Cdd:COG1196    391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA--ELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1403 ISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAK-- 1480
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAal 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1481 QQIQRKLQAALISRKEALKENKslqeelsLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRS 1560
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAK-------AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1561 LLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEyeillqsyenvsnEAERIQHVVEA 1640
Cdd:COG1196    622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA-------------EAELEELAERL 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1641 VRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKEcmETLL 1720
Cdd:COG1196    689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL--EELE 766

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1622909128 1721 SSNASMKEEVER---VKM----EYETLSKKFQSLMSEKDSLSEEVQDL 1761
Cdd:COG1196    767 RELERLEREIEAlgpVNLlaieEYEELEERYDFLSEQREDLEEARETL 814
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1837-2341 2.77e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.08  E-value: 2.77e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1837 INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNallsQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKET 1916
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEE----LIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1917 AEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQqlVKEKTKVESEIRKEYLEKI 1996
Cdd:PRK03918   233 LEELKEEIEE-LEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKE--KAEEYIKLSEFYEEYLDEL 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1997 QGAQKEPGN-KSHAKELQELLKE---KQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHR 2072
Cdd:PRK03918   310 REIEKRLSRlEEEINGIEERIKEleeKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2073 KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQmKQKDEDLERRLEQAEEKHL------------KEK 2140
Cdd:PRK03918   390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA-KGKCPVCGRELTEEHRKELleeytaelkrieKEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2141 KNMQEKLDALRREKVHLE----------------ETIGEIQVTLNKKDKE-IQQVQENLDSTVAQLAAFTKSMSSLQDDR 2203
Cdd:PRK03918   469 KEIEEKERKLRKELRELEkvlkkeseliklkelaEQLKELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLKGEIKSLKKEL 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2204 DRvIDEAKKWERKFSDAIQTKEEEI-----RLKEENCSVLKD------QLRQMSIHMEELKINISRLEHDKQIWES---- 2268
Cdd:PRK03918   549 EK-LEELKKKLAELEKKLDELEEELaellkELEELGFESVEEleerlkELEPFYNEYLELKDAEKELEREEKELKKleee 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2269 --KAQTEVQLQQKVCDTLQGENKELLSQLEETRH-----LYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLE 2341
Cdd:PRK03918   628 ldKAFEELAETEKRLEELRKELEELEKKYSEEEYeelreEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 557-1247 2.84e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 2.84e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  557 KHKELSVLLLEMKEAQEEIAFLKLQLqgKRAEEGDHEVLDQKEMKQMEGEGIapikmevfledtgqnfplmpneESSLPA 636
Cdd:TIGR02168  223 RELELALLVLRLEELREELEELQEEL--KEAEEELEELTAELQELEEKLEEL----------------------RLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  637 VEKEQAS-TEHQNRTSEEISlndagvELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYE----- 710
Cdd:TIGR02168  279 LEEEIEElQKELYALANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEelkee 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  711 -----KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV--------VTELRAQVRQLEMNLAE 777
Cdd:TIGR02168  353 lesleAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEArlerledrRERLQQEIEELLKKLEE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  778 AERQR-RFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKES------EVL 850
Cdd:TIGR02168  433 AELKElQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGfsegvkALL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  851 EGAERVRHISSKVEELSQALSQKELEIAK-----MDQLLLEKKRDVETLQQTIEEKDQ-QVTEISFSMTEKMVQLNEEKF 924
Cdd:TIGR02168  513 KNQSGLSGILGVLSELISVDEGYEAAIEAalggrLQAVVVENLNAAKKAIAFLKQNELgRVTFLPLDSIKGTEIQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  925 SLGVEIKTLKEQLNLLSRAEEAKK------------EQVEEDNEVVSGLKQNY-------DEMSPAGLISKEELQHEFDL 985
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvDDLDNALELAKKLRPGYrivtldgDLVRPGGVITGGSAKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  986 LK-----KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEI 1060
Cdd:TIGR02168  673 LErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1061 EISLKQTISEKEVELEHIRKDLEEKMAAE---EQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTtsNTDASDG 1137
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR--ERLESLE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1138 DSVALVKETVVISPPGTDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAI---LKKAQEKERHLREELKQQKDDY 1214
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLeeaLALLRSELEELSEELRELESKR 910

                          730       740       750
                   ....*....|....*....|....*....|...
gi 1622909128 1215 NRLQEQFDEQSKENENIGDQLRQLQIQVRESID 1247
Cdd:TIGR02168  911 SELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1889-2495 4.38e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.31  E-value: 4.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1889 LQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLmnqlaelngsignycQDVTDAQIKNELLESEMKNLKKCVS 1968
Cdd:PRK03918   167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVL---------------REINEISSELPELREELEKLEKEVK 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1969 ELEEEKQ---QLVKEKTKVESEIRKEYlEKIQGAQKEPGNKshaKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2045
Cdd:PRK03918   232 ELEELKEeieELEKELESLEGSKRKLE-EKIRELEERIEEL---KKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLD 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2046 ALEFVQTESQKdLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLK--KELQSNKESVKSQMKQKD- 2122
Cdd:PRK03918   308 ELREIEKRLSR-LEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEeaKAKKEELERLKKRLTGLTp 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2123 EDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLN--KKDKEIQQVQENL---DSTVAQLAAFTKSMS 2197
Cdd:PRK03918   387 EKLEKELEELE----KAKEEIEEEISKITARIGELKKEIKELKKAIEelKKAKGKCPVCGRElteEHRKELLEEYTAELK 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2198 SLQDDRDRVIDEAKKWERKFsdaiqTKEEEIRLKEENCSVLKDQLRQMSIHMEELK-INISRLEhdkqiwesKAQTEVQL 2276
Cdd:PRK03918   463 RIEKELKEIEEKERKLRKEL-----RELEKVLKKESELIKLKELAEQLKELEEKLKkYNLEELE--------KKAEEYEK 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2277 QQKVCDTLQGENKELLSQLEETRHLyhnsQNELAKLESELNILKDQLTDLSNSLEKCK-EQKENLEGIIRQQEaDIQNSK 2355
Cdd:PRK03918   530 LKEKLIKLKGEIKSLKKELEKLEEL----KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELE-PFYNEY 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2356 FSYEQLETDLQASRELTSRLHEEINMKEqKMISLLSGKEEAIQVAIAELRQQHDKE----IKELENLLSQEEEENIVLEE 2431
Cdd:PRK03918   605 LELKDAEKELEREEKELKKLEEELDKAF-EELAETEKRLEELRKELEELEKKYSEEeyeeLREEYLELSRELAGLRAELE 683

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622909128 2432 ENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILE 2495
Cdd:PRK03918   684 ELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1317-1980 4.77e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 58.88  E-value: 4.77e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1317 ETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGL-EHLRELQPE 1395
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1396 LDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEhderIKQLQVELCEMKQKPEEIEE 1475
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQ----KEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1476 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLIT 1555
Cdd:TIGR04523  188 NIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1556 EMDRSLLEnqslsgsCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSewQEKHKELQKEYEILLQSYENVSNEAERIQ 1635
Cdd:TIGR04523  268 QLSEKQKE-------LEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWN--KELKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1636 HVVEAVRQEKQELYGKlrstEANKKETEKQLQEaekemeemkekmrkfaksKQQKILELEEENDRLraevhpaggtaKEC 1715
Cdd:TIGR04523  339 QLNEQISQLKKELTNS----ESENSEKQRELEE------------------KQNEIEKLKKENQSY-----------KQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1716 METLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLeaTEKHDNQMNVTEEATQSI 1795
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL--TNQDSVKELIIKNLDNTR 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1796 PGETEDQDSLSMSTRPAcsesvpsENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAL 1875
Cdd:TIGR04523  464 ESLETQLKVLSRSINKI-------KQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEK 536

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1876 LSQISTKDGELKLLQEEVSKMNL------LNQQIQEELSRVTKLKETAEEEKDDLEER------LMNQLAELNGSIGNYC 1943
Cdd:TIGR04523  537 ESKISDLEDELNKDDFELKKENLekeideKNKEIEELKQTQKSLKKKQEEKQELIDQKekekkdLIKEIEEKEKKISSLE 616

                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 1622909128 1944 QDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKE 1980
Cdd:TIGR04523  617 KELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1307-1780 4.93e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.31  E-value: 4.93e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1307 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVfqlqDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGL 1386
Cdd:PRK03918   189 ENIEELIKEKEKELEEVLREINEISSELPELREEL----EKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIREL 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1387 E-HLRELQPELDELQKL------ISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQL 1459
Cdd:PRK03918   265 EeRIEELKKEIEELEEKvkelkeLKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK-ELEEKEERLEEL 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1460 QVELCEMKQKPEEIEEESRAKQQIQRKLqaaliSRKEALKENkslqeelsLARDTIEHLTKSLADVESHVSAQNKEKDRV 1539
Cdd:PRK03918   344 KKKLKELEKRLEELEERHELYEEAKAKK-----EELERLKKR--------LTGLTPEKLEKELEELEKAKEEIEEEISKI 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1540 LGRLALLQEErdklITEMDRSLLENQSLSGSCESLKlalEGLTEDKEKLVKEIESLKSSKIA-ESSEWQEKHKELQKEye 1618
Cdd:PRK03918   411 TARIGELKKE----IKELKKAIEELKKAKGKCPVCG---RELTEEHRKELLEEYTAELKRIEkELKEIEEKERKLRKE-- 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1619 ilLQSYENVSNEAERIQHVVEAVRQEKqELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEEN 1698
Cdd:PRK03918   482 --LRELEKVLKKESELIKLKELAEQLK-ELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKL 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1699 DRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEAT 1778
Cdd:PRK03918   559 AELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAET 638


                   ..
gi 1622909128 1779 EK 1780
Cdd:PRK03918   639 EK 640
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1736-2495 9.95e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.16  E-value: 9.95e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1736 EYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQ--MNVTEEATQSIPGETEDQDSLSMSTRPAC 1813
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkiKDLGEEEQLRVKEKIGELEAEIASLERSI 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1814 SESVPSENSANPAVSEDVSshdEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEV 1893
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEA---EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1894 S----KMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSE 1969
Cdd:TIGR02169  388 KdyreKLEKLKREINELKRELDRLQEELQRLSEELAD-LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1970 LEEEKQQLVKEKTKVESEIRK---EYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK-ISALERT-- 2043
Cdd:TIGR02169  467 YEQELYDLKEEYDRVEKELSKlqrELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyATAIEVAag 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2044 --------------VKALEFVQTE---------------SQKDLEITKEN-----LAQAVEHRKKAQAelaSFKVLLDDT 2089
Cdd:TIGR02169  547 nrlnnvvveddavaKEAIELLKRRkagratflplnkmrdERRDLSILSEDgvigfAVDLVEFDPKYEP---AFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2090 qseaarVLADNLKLKKELQSNKESV--------KSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETI 2161
Cdd:TIGR02169  624 ------LVVEDIEAARRLMGKYRMVtlegelfeKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2162 GEIQvtlnkkdKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQ 2241
Cdd:TIGR02169  698 RRIE-------NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2242 lrQMSIHMEELKINisrlehdkQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKD 2321
Cdd:TIGR02169  771 --EEDLHKLEEALN--------DLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2322 QLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKM--ISLLSGKEEAIQV 2399
Cdd:TIGR02169  841 QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIeeLEAQIEKKRKRLS 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2400 AIAELRQQHDKEIKELENLLSQEEEENIVLEEENK--KAVDKTNQLMETLNAIKKENIQQ----KAQLDSFVKSMSSLQN 2473
Cdd:TIGR02169  921 ELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDvqAELQRVEEEIRALEPVNMLAIQEyeevLKRLDELKEKRAKLEE 1000

                          810       820
                   ....*....|....*....|..
gi 1622909128 2474 DRDRIVGDYQQLEERHLSVILE 2495
Cdd:TIGR02169 1001 ERKAILERIEEYEKKKREVFME 1022
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1304-1937 1.28e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 1.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1304 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEvfQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQI 1383
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQD--RIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQA 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1384 AGLEHLRELQpeldelqklISEKEEDVSYLSGQLREKEAALtkiqteiieqEDLIKALHTQLEMQakehderikqlQVEL 1463
Cdd:pfam15921  309 RNQNSMYMRQ---------LSDLESTVSQLRSELREAKRMY----------EDKIEELEKQLVLA-----------NSEL 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1464 CEMKQKPEEIEEESRAKQQIQRKLQAALISRKEAL----KENKSLQEELSLARDTIEHLTKSLADveshvsaQNKEKDRV 1539
Cdd:pfam15921  359 TEARTERDQFSQESGNLDDQLQKLLADLHKREKELslekEQNKRLWDRDTGNSITIDHLRRELDD-------RNMEVQRL 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1540 LgrlALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIA-ESSE---------WQEK 1609
Cdd:pfam15921  432 E---ALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTlESSErtvsdltasLQEK 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1610 HK----------ELQKEYEILLQSYENVSNEAERIQH-----------------VVEAVRQEKQ---ELYGKLRSTEANK 1659
Cdd:pfam15921  509 ERaieatnaeitKLRSRVDLKLQELQHLKNEGDHLRNvqtecealklqmaekdkVIEILRQQIEnmtQLVGQHGRTAGAM 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1660 KETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEvhpaggtakecMETLLSSNASMKEEVERVKMEYET 1739
Cdd:pfam15921  589 QVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELE-----------KVKLVNAGSERLRAVKDIKQERDQ 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1740 LSKKFQSLMSEKDSLSEEVQDLKHQLESNVskqanlEATEKHDNQMNVTEEATQSipgETEDQDSLSMSTrpacsesvps 1819
Cdd:pfam15921  658 LLNEVKTSRNELNSLSEDYEVLKRNFRNKS------EEMETTTNKLKMQLKSAQS---ELEQTRNTLKSM---------- 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1820 ENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEE--------------EKQKNKEFSQTLENERNALLSQISTKDGE 1885
Cdd:pfam15921  719 EGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEamtnankekhflkeEKNKLSQELSTVATEKNKMAGELEVLRSQ 798

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622909128 1886 LKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNG 1937
Cdd:pfam15921  799 ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1949-2762 1.29e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 1.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1949 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2028
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2029 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2108
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2109 SNKESVKSQMKQKDEDLERRL------EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2182
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREaeeeeeEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2183 dstvaQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHD 2262
Cdd:pfam02463  412 -----ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2263 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILK--DQLTDLSNSLEKCKEQKENL 2340
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAisTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2341 EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS 2420
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2421 QEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLI 2500
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2501 QEAAAENNKLKEEIR----------GLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNK 2570
Cdd:pfam02463  727 VQEAQDKINEELKLLkqkideeeeeEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2571 YAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALL 2650
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2651 SSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKD 2730
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1622909128 2731 LTAQIQSFGRSMSSLQNSRDHANEELDELKRK 2762
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1305-1780 1.65e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.38  E-value: 1.65e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1305 SVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINkqglEIESLKTASHEAEVRAESLQQKLESSQLQIA 1384
Cdd:PRK03918   239 EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK----ELKELKEKAEEYIKLSEFYEEYLDELREIEK 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1385 GLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDlIKALHTQLE-MQAKEHDERIKQLQVEL 1463
Cdd:PRK03918   315 RLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEE-AKAKKEELErLKKRLTGLTPEKLEKEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1464 CEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTI--EHLTKSLADVESHVSAQNKEKDRVLG 1541
Cdd:PRK03918   394 EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELteEHRKELLEEYTAELKRIEKELKEIEE 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1542 RLALLQEERDKLITEM--DRSLLENQSLSGSCESLKLALEGLT-EDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYE 1618
Cdd:PRK03918   474 KERKLRKELRELEKVLkkESELIKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1619 IllqsyenvSNEAERIQHVVEAVRQEKQELYGKLRSTE-ANKKETEKQLQEAEKEMEE--MKEKMRKFAKSKQQKILELE 1695
Cdd:PRK03918   554 L--------KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPFYNEylELKDAEKELEREEKELKKLE 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1696 EENDRLRAEVHPAGGTAKECMETLLSSNAS--------MKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLES 1767
Cdd:PRK03918   626 EELDKAFEELAETEKRLEELRKELEELEKKyseeeyeeLREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705

                          490
                   ....*....|...
gi 1622909128 1768 NVSKQANLEATEK 1780
Cdd:PRK03918   706 REKAKKELEKLEK 718
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 945-1761 1.75e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  945 EAKKEQVEEDNEVVsglKQNYDEMSpaglISKEELQHEFDLLKKENEQRKRKLqaALINRKELLQRVSRLEEELANLKDQ 1024
Cdd:TIGR02169  169 DRKKEKALEELEEV---EENIERLD----LIIDEKRQQLERLRREREKAERYQ--ALLKEKREYEGYELLKEKEALERQK 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1025 SKKEIPLSESERgEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQ 1104
Cdd:TIGR02169  240 EAIERQLASLEE-ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1105 DKTNQIDLLQAEISENQVIIQklttsntdasdgdsvalvketvvisppgtdsgehwkpELEEKILALEKEKEQLQKKLQE 1184
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIE-------------------------------------ELEREIEEERKRRDKLTEEYAE 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1185 ALTSRKAILKKAQEKE---RHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREsIDGKLPSPDQQewcsp 1261
Cdd:TIGR02169  362 LKEELEDLRAELEEVDkefAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD-LNAAIAGIEAK----- 435

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1262 TPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQggTSVAQIKAQLKEIETEKEKLE--LKISSTTSELTKKSE 1339
Cdd:TIGR02169  436 INELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK--EEYDRVEKELSKLQRELAEAEaqARASEERVRGGRAVE 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1340 EVF------------QLQDQINKQGLEIES-----LKTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKL 1402
Cdd:TIGR02169  514 EVLkasiqgvhgtvaQLGSVGERYATAIEVaagnrLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSIL 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1403 ISEKEEDVSY----------------------------------------LSGQLREKEAALTKIQTEIIEQEDLIKALH 1442
Cdd:TIGR02169  594 SEDGVIGFAVdlvefdpkyepafkyvfgdtlvvedieaarrlmgkyrmvtLEGELFEKSGAMTGGSRAPRGGILFSRSEP 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1443 TQLEMQAkehdERIKQLQVELCEMKQKPEEIEEESRAKQQ----IQRKLQAALISRKEALKENKSLQEELSLARDTIEHL 1518
Cdd:TIGR02169  674 AELQRLR----ERLEGLKRELSSLQSELRRIENRLDELSQelsdASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1519 TKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLEN------------QSLSGSCESLKLALEGLTEDKE 1586
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelskleeevSRIEARLREIEQKLNRLTLEKE 829

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1587 KLVKEIESLKSSKIaessEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQL 1666
Cdd:TIGR02169  830 YLEKEIQELQEQRI----DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1667 QEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTA------------KECMETLLSSNASMKEEVERVK 1734
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELsledvqaelqrvEEEIRALEPVNMLAIQEYEEVL 985

                          890       900
                   ....*....|....*....|....*..
gi 1622909128 1735 MEYETLSKKFQSLMSEKDSLSEEVQDL 1761
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 47-528 1.81e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.81e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128   47 QEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEEKKAADNKIKKLKLHAKAKLTSLNKHIEEMKAQGGTVLLTEp 126
Cdd:COG1196    332 LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE- 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  127 QSEEQLSKHDKSSTEEEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMKQQLQEKEELISTLQ 206
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  207 AQLSQTQAEQAAQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKL----------------RVLQRKLEEHEESL 270
Cdd:COG1196    491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALeaalaaalqnivveddEVAAAAIEYLKAAK 570

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  271 VGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEkmELEVAERKLSFHNLQEEMRHLLEQ 350
Cdd:COG1196    571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLG--RTLVAARLEAALRRAVTLAGRLRE 648

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  351 LEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQLEDQLQ 430
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  431 QKSKEISQFLNRLPLQQHETASQTCFPDVYNEGTQAVtEENIASLQKRVVELenekGALLLSSI-ELEELKAENEKLSSQ 509
Cdd:COG1196    729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL-ERELERLEREIEAL----GPVNLLAIeEYEELEERYDFLSEQ 803

                          490       500
                   ....*....|....*....|....
gi 1622909128  510 I-TLLEA----QNRIGEADREVSE 528
Cdd:COG1196    804 ReDLEEAretlEEAIEEIDRETRE 827
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1389-1605 2.06e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 2.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1389 LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1468
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1469 KPEEIEEESRAKQQIQRKLQAALI----SRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLA 1544
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909128 1545 LLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSE 1605
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1435-2180 2.43e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.05  E-value: 2.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1435 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1511
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKfylRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1512 RDT-IEHLTKSLADVESHVSaqnkekdRVLGRLALLQEERDKLITEMDR-SLLENQSLSGSCESLKLALEgltedkeklv 1589
Cdd:pfam15921  168 SNTqIEQLRKMMLSHEGVLQ-------EIRSILVDFEEASGKKIYEHDSmSTMHFRSLGSAISKILRELD---------- 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1590 KEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYEnvsneaERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQea 1669
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLE-- 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1670 ekemeEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLms 1749
Cdd:pfam15921  303 -----IIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNL-- 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1750 eKDSLSEEVQDL-KHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVS 1828
Cdd:pfam15921  376 -DDQLQKLLADLhKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1829 EDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKM----NLLNQQIQ 1904
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLrsrvDLKLQELQ 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1905 EELSRVTKLKETAEE---------EKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQ 1975
Cdd:pfam15921  535 HLKNEGDHLRNVQTEcealklqmaEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKD 614

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1976 QLVKEKTKVESEIRKEYLEKIQ----GAQKEPGNKSHAKELQELLKE---KQQEVKQLQKDC----IRYQEKISALERTV 2044
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKlvnaGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTT 694

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2045 KALEFVQTESQKDLEITKENL-------AQAVEHRKKAQAELASFKVLLDDTQSEaarvladnLKLKKELQSNKESVKSQ 2117
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLksmegsdGHAMKVAMGMQKQITAKRGQIDALQSK--------IQFLEEAMTNANKEKHF 766

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622909128 2118 MKQKDEDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQE 2180
Cdd:pfam15921  767 LKEEKNKLSQELSTVA----TEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1299-1545 2.68e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 2.68e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1299 ALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLES 1378
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1379 SQLQIAglehlrELQPELDELQKLISE------KEEDVSYLSGQLREKEAA--------LTKIQTEIIEQEDLIKALHTQ 1444
Cdd:COG4942     88 LEKEIA------ELRAELEAQKEELAEllralyRLGRQPPLALLLSPEDFLdavrrlqyLKYLAPARREQAEELRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1445 LEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELslaRDTIEHLTKSLAD 1524
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL---EALIARLEAEAAA 238

                          250       260
                   ....*....|....*....|.
gi 1622909128 1525 VESHVSAQNKEKDRvlGRLAL 1545
Cdd:COG4942    239 AAERTPAAGFAALK--GKLPW 257
PTZ00121 PTZ00121
MAEBL; Provisional
 1307-1871 4.25e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.30  E-value: 4.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1307 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTAshEAEVRAESLQQKLESSQLQIAGL 1386
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE--EAKKKADAAKKKAEEKKKADEAK 1397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1387 EHLRELQPELDELQKLISEKE--EDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelc 1464
Cdd:PTZ00121  1398 KKAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD---- 1473

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1465 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQ----EELSLARDTIEHLTKSLADvESHVSAQNKEKDRVL 1540
Cdd:PTZ00121  1474 EAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEakkaEEAKKADEAKKAEEAKKAD-EAKKAEEKKKADELK 1552

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1541 GRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEIL 1620
Cdd:PTZ00121  1553 KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK 1632

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1621 LQSYENVSNEAERIQHvVEAVRQEKQElyGKLRSTEANKKETE-----KQLQEAEKEMEEMKEKMRKFA--KSKQQKILE 1693
Cdd:PTZ00121  1633 KKVEQLKKKEAEEKKK-AEELKKAEEE--NKIKAAEEAKKAEEdkkkaEEAKKAEEDEKKAAEALKKEAeeAKKAEELKK 1709

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1694 LEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEyETLSKKFQSLMSEKDSLSEEVQDLKHQL------ES 1767
Cdd:PTZ00121  1710 KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVieeeldEE 1788

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1768 NVSKQANLEATEK--HDNQMNVTEEATQSIP-----GETEDQDS--LSMSTRPACSESVPSENSANPAVSEDVSSHDEIN 1838
Cdd:PTZ00121  1789 DEKRRMEVDKKIKdiFDNFANIIEGGKEGNLvindsKEMEDSAIkeVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEA 1868

                          570       580       590
                   ....*....|....*....|....*....|...
gi 1622909128 1839 NYLQQIDQLKERIAGLEEEKQKNKEFSQTLENE 1871
Cdd:PTZ00121  1869 DFNKEKDLKEDDEEEIEEADEIEKIDKDDIERE 1901
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1582-2159 4.41e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.84  E-value: 4.41e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1582 TEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIqhvvEAVRQEKQELYGKLRSTEANKKE 1661
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI----EELEKELESLEGSKRKLEEKIRE 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1662 TEKQLQEAEKEMEEMKEKMR----------------KFAKSKQQKILELEEENDRLRAEVhpaggtakECMETLLSSNAS 1725
Cdd:PRK03918   264 LEERIEELKKEIEELEEKVKelkelkekaeeyiklsEFYEEYLDELREIEKRLSRLEEEI--------NGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1726 MKEEVERVKMEYETLSKKFQSLmSEKDSLSEEVQDLKHQLESNVSKQANL---EATEKHDNQMNVTEEATQSIPGETEDQ 1802
Cdd:PRK03918   336 KEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELERLKKRLTGLtpeKLEKELEELEKAKEEIEEEISKITARI 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1803 DSLS--MSTRPACSESVPSENSANPAVSEDVSSHDE---INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLS 1877
Cdd:PRK03918   415 GELKkeIKELKKAIEELKKAKGKCPVCGRELTEEHRkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1878 QISTKD--GELKLLQEEVSKMNLlnqqiqEELSRVTKLKETAEEEKDDLEERLMNQLAELNgsignycqdvtdaqiKNEL 1955
Cdd:PRK03918   495 LIKLKElaEQLKELEEKLKKYNL------EELEKKAEEYEKLKEKLIKLKGEIKSLKKELE---------------KLEE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1956 LESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIqgaqkepgnkshaKELQELLKEkQQEVKQLQKDCIRYQE 2035
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL-------------KELEPFYNE-YLELKDAEKELEREEK 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2036 KISALERTVKALEFVQTESQKDLEITKENLAQAveHRKKAQAELASFKVLLDDTQSEAARVLADnlklKKELQSNKESVK 2115
Cdd:PRK03918   620 ELKKLEEELDKAFEELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAE----LEELEKRREEIK 693

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1622909128 2116 SQMKQKDEDLERRLEQAEEKHLKEK--KNMQEKLDALRREKVHLEE 2159
Cdd:PRK03918   694 KTLEKLKEELEEREKAKKELEKLEKalERVEELREKVKKYKALLKE 739
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 548-1427 5.12e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.83  E-value: 5.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  548 DVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQgkrAEEGDHEVLdQKEMKQMEgegiapikmevfledtgqnfplm 627
Cdd:TIGR02168  228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQ---ELEEKLEEL-RLEVSELE----------------------- 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  628 pneesslpavEKEQASTEHQNRTSEEISlndagvELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQE 707
Cdd:TIGR02168  281 ----------EEIEELQKELYALANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  708 IYE---KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV-VTELRAQVRQLEmnlaeaERQRR 783
Cdd:TIGR02168  345 KLEelkEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNeIERLEARLERLE------DRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  784 FDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKV 863
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  864 EELSQAlsQKELEIAKMDQLLLEKKRDVetLQQTIEEkdqqvteisfsmtekmvqlnEEKFSLGVEIkTLKEQLN-LLSR 942
Cdd:TIGR02168  499 ENLEGF--SEGVKALLKNQSGLSGILGV--LSELISV--------------------DEGYEAAIEA-ALGGRLQaVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  943 AEEAKKEQVEEDNEVVSG------LKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINrkeLLQRVsRLEE 1016
Cdd:TIGR02168  554 NLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSY---LLGGV-LVVD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1017 ELANLKDQSKKEIPLSE---------SERGEVEEDKENKEYSekcVTSKCQEIEIsLKQTISEKEVELEHIRKDLEEKMA 1087
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRivtldgdlvRPGGVITGGSAKTNSS---ILERRREIEE-LEEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1088 AEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVisppgtdsgEHWKPELEEK 1167
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL---------EERLEEAEEE 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1168 ILALEKEKEQLQ---KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRE 1244
Cdd:TIGR02168  777 LAEAEAEIEELEaqiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1245 SIdgklpspdqqewcsptpgleeplfkateqhhtqpvlesnlcpdwpshsedASALQGGTSVAQIKAQLKEIETEKEKLE 1324
Cdd:TIGR02168  857 LA--------------------------------------------------AEIEELEELIEELESELEALLNERASLE 886

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1325 LKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGlehlrELQPELDELQKLIS 1404
Cdd:TIGR02168  887 EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE-----EYSLTLEEAEALEN 961

                          890       900
                   ....*....|....*....|...
gi 1622909128 1405 EKEEDVSYLSGQLREKEAALTKI 1427
Cdd:TIGR02168  962 KIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1070-1669 5.20e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 5.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1070 EKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvi 1149
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA--- 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1150 sppgtdsgehwkpELEEKILALEKEKEQLQKKLQEALTSRKAIlkkaQEKERHLREELKQQKDDYNRLQEQFDEQSKENE 1229
Cdd:COG1196    299 -------------RLEQDIARLEERRRELEERLEELEEELAEL----EEELEELEEELEELEEELEEAEEELEEAEAELA 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1230 NIGDQLRQLQIQVREsidgklpspDQQEWcsptpgleeplfkateqhhtqpvlesnlcpdwpsHSEDASALQGGTSVAQI 1309
Cdd:COG1196    362 EAEEALLEAEAELAE---------AEEEL----------------------------------EELAEELLEALRAAAEL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1310 KAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE-H 1388
Cdd:COG1196    399 AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEaA 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1389 LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEdLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1468
Cdd:COG1196    479 LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA-VAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1469 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRV-------LG 1541
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVaarleaaLR 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1542 RLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILL 1621
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1622909128 1622 QSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1669
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1354-1805 5.30e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.82  E-value: 5.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1354 EIESLKTASHEAEVRAESLQQKLESSQLQiagLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEI-- 1431
Cdd:PRK02224   221 EIERYEEQREQARETRDEADEVLEEHEER---REELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERdd 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1432 -IEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ--------------KPEEIEEESRAKQQIQRKLQAALISRKE 1496
Cdd:PRK02224   298 lLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVaaqahneeaeslreDADDLEERAEELREEAAELESELEEARE 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1497 ALKENKS----LQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRL----ALLQEERDKLitEMDRSLLE----- 1563
Cdd:PRK02224   378 AVEDRREeieeLEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREaeleATLRTARERV--EEAEALLEagkcp 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1564 --NQSLSGSceSLKLALEGLTEDKEKLVKEIESLKS--SKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVE 1639
Cdd:PRK02224   456 ecGQPVEGS--PHVETIEEDRERVEELEAELEDLEEevEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1640 AVRQEKQELYGKLRSTEANKKETEKQLQEAekemEEMKEKMRKFAKSKQQKILELEEENDRLRAevhpaggtakecMETL 1719
Cdd:PRK02224   534 EKRERAEELRERAAELEAEAEEKREAAAEA----EEEAEEAREEVAELNSKLAELKERIESLER------------IRTL 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1720 LSSNASMKEEVERVKMEYETLSKKFQslmSEKDSLSEEvQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGET 1799
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELND---ERRERLAEK-RERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673


                   ....*.
gi 1622909128 1800 EDQDSL 1805
Cdd:PRK02224   674 EERDDL 679
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1166-1872 5.46e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.84  E-value: 5.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1166 EKILALEKEKEQ-----LQKKLQEALTSRKAILKKAQEKERHLREelkqqkddynrLQEQFDEQSKENENIGDQLRQLQI 1240
Cdd:TIGR02169  211 ERYQALLKEKREyegyeLLKEKEALERQKEAIERQLASLEEELEK-----------LTEEISELEKRLEEIEQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1241 QVRESIDGklpspdqqEWCSPTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsEDASAlqggtSVAQIKAQLKEIETEK 1320
Cdd:TIGR02169  280 KIKDLGEE--------EQLRVKEKIGELEAEIASLERSIAEKEREL--------EDAEE-----RLAKLEAEIDKLLAEI 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1321 EKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQlqiaglEHLRELQPELDELQ 1400
Cdd:TIGR02169  339 EELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK------REINELKRELDRLQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1401 KLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQlqvELCEMKQKPEEIEEESRAK 1480
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE-QLAADLSKYEQ---ELYDLKEEYDRVEKELSKL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1481 QQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESH------------------------VSAQNKEK 1536
Cdd:TIGR02169  489 QRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaagnrlnnvvveddavaKEAIELLK 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1537 DRVLGRLALL------QEERDKLITEMD---------------------------------------------------- 1558
Cdd:TIGR02169  569 RRKAGRATFLplnkmrDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgdtlvvedieaarrlmgkyrmvtlegel 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1559 --------------RSLLENQ-SLSGSCESLKLALEGLTEDKEKLVKE---IESLKSSKIAESSEWQEKHKELQKEYEIL 1620
Cdd:TIGR02169  649 feksgamtggsrapRGGILFSrSEPAELQRLRERLEGLKRELSSLQSElrrIENRLDELSQELSDASRKIGEIEKEIEQL 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1621 LQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQL-QEAEKEMEEMKEKMRKFAKSKQQKILELEEEND 1699
Cdd:TIGR02169  729 EQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLhKLEEALNDLEARLSHSRIPEIQAELSKLEEEVS 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1700 RLRA----------EVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQS--------------LMSEKDSLS 1755
Cdd:TIGR02169  809 RIEArlreieqklnRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEleeeleeleaalrdLESRLGDLK 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1756 EEVQDLKHQLESNVSKQANLEAT----EKHDNQMNVTEEATQSIPGETEDQDSlSMSTRPACSESVPSENSANPAVSEDV 1831
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQiekkRKRLSELKAKLEALEEELSEIEDPKG-EDEEIPEEELSLEDVQAELQRVEEEI 967

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1622909128 1832 SSHDEINN--------YLQQIDQLKERIAGLEEEKQKNKEFSQTLENER 1872
Cdd:TIGR02169  968 RALEPVNMlaiqeyeeVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1885-2738 5.51e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 5.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1885 ELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELN---GSIGNYCQDVTDAQIKNELLESEMK 1961
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYllyLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1962 NLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALE 2041
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2042 RTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQK 2121
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLEL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2122 DEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTvaqlaaftkSMSSLQD 2201
Cdd:pfam02463  414 ARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKET---------QLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2202 DRDRVIDEAKKWERKFSdaiQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVC 2281
Cdd:pfam02463  485 QLELLLSRQKLEERSQK---ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2282 DTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQL 2361
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2362 ETDLQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTN 2441
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2442 QLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIvGDYQQLEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHM 2521
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLK-KEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2522 DDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRD 2601
Cdd:pfam02463  801 EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2602 LSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDK 2681
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE 960

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 2682 LKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSF 2738
Cdd:pfam02463  961 RNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1430-2028 6.44e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.46  E-value: 6.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1430 EIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELS 1509
Cdd:PRK03918   183 KFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIR 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1510 LARDTIEHLTKSLADVEshvsaqnkEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLtedkEKLV 1589
Cdd:PRK03918   263 ELEERIEELKKEIEELE--------EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI----EERI 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1590 KEIESLKSskiaESSEWQEKHKELQKEYEILLQSYEnvsnEAERIQHVVEAVRQEKQELYGKlrsteaNKKETEKQLQEA 1669
Cdd:PRK03918   331 KELEEKEE----RLEELKKKLKELEKRLEELEERHE----LYEEAKAKKEELERLKKRLTGL------TPEKLEKELEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1670 EKEMEEMKEKMRKFakskQQKILELEEENDRLRAEVHPAGGTAKECMetlLSSNASMKEEVERVKMEYETLSKKFQSLMS 1749
Cdd:PRK03918   397 EKAKEEIEEEISKI----TARIGELKKEIKELKKAIEELKKAKGKCP---VCGRELTEEHRKELLEEYTAELKRIEKELK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1750 EKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSanpAVSE 1829
Cdd:PRK03918   470 EIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIK---SLKK 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1830 DVSSHDEINNYLQqidQLKERIAGLEEEKqknKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSR 1909
Cdd:PRK03918   547 ELEKLEELKKKLA---ELEKKLDELEEEL---AELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1910 VTKLKETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNelLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR 1989
Cdd:PRK03918   621 LKKLEEELDKAFEELAE-TEKRLEELRKELEELEKKYSEEEYEE--LREEYLELSRELAGLRAELEELEKRREEIKKTLE 697

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1622909128 1990 --KEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2028
Cdd:PRK03918   698 klKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLK 738
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1381-1656 6.52e-07

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 55.32  E-value: 6.52e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1381 LQIAGLEhlRELQPELDELQKL----ISEKEEDVSYLsgQLREKEAALTKIQTEIIEQEDLIKALHT----QLEMQAKEH 1452
Cdd:PRK05771     9 VLIVTLK--SYKDEVLEALHELgvvhIEDLKEELSNE--RLRKLRSLLTKLSEALDKLRSYLPKLNPlreeKKKVSVKSL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1453 DERIKQLQVELcemkqkpEEIEEESRAKQQIQRKLQA---ALISRKEALKENKSLQEELSLARDT-----------IEHL 1518
Cdd:PRK05771    85 EELIKDVEEEL-------EKIEKEIKELEEEISELENeikELEQEIERLEPWGNFDLDLSLLLGFkyvsvfvgtvpEDKL 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1519 TKSLADVESHVS---AQNKEKDRVLgrLALLQEERDKLITEMDRSLLENQSLSGScESLKLALEGLTEDKEKLVKEIESL 1595
Cdd:PRK05771   158 EELKLESDVENVeyiSTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE-GTPSELIREIKEELEEIEKERESL 234

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909128 1596 KsSKIAESSEwqekhkelqKEYEILLQSYENVSNEAERiqhvveavrqekQELYGKLRSTE 1656
Cdd:PRK05771   235 L-EELKELAK---------KYLEELLALYEYLEIELER------------AEALSKFLKTD 273
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 921-1582 6.86e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 55.36  E-value: 6.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  921 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEfDLLKKENEQRKRKLQAA 1000
Cdd:TIGR00618  187 AKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQK-REAQEEQLKKQQLLKQL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1001 LINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRK 1080
Cdd:TIGR00618  266 RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRR 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1081 DLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPPGTDSGEHW 1160
Cdd:TIGR00618  346 LLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQ 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1161 KPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDdynrlQEQFDEQSKENENIGDQLRQLQI 1240
Cdd:TIGR00618  426 LAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-----KEQIHLQETRKKAVVLARLLELQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1241 QVRESIDGKLPSPDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNlcpdwpshSEDASALQGGTSVAQIKAQLKEIETEK 1320
Cdd:TIGR00618  501 EEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE--------DVYHQLTSERKQRASLKEQMQEIQQSF 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1321 EKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAE----------SLQQKLESSQLQIAGLEHLR 1390
Cdd:TIGR00618  573 SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpeqdlqdvrlHLQQCSQELALKLTALHALQ 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1391 ELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDL--IKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1468
Cdd:TIGR00618  653 LTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLaqCQTLLRELETHIEEYDREFNEIENASSSLGS 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1469 kpeEIEEESRAKQQIQRKLQAaliSRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQE 1548
Cdd:TIGR00618  733 ---DLAAREDALNQSLKELMH---QARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1622909128 1549 E-RDKLITEMDRSLLENQSLSGSCESLKLALEGLT 1582
Cdd:TIGR00618  807 EiGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKS 841
PTZ00121 PTZ00121
MAEBL; Provisional
 704-1231 8.54e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.15  E-value: 8.54e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  704 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQ 781
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  782 RRFDYESQTAHHNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 854
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  855 RVRHISSKVEELSQA--LSQKELEIAKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 930
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  931 KTLKEqlnlLSRAEEAKKEQVEEDNEVvsglKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1010
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1011 VSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEE 1090
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1091 QLQAlvKEMNQTLQDKTNQIDLLQAEISENQviiqklttsntdasdgdsvalvketvvisppgtdsgehwKPELEEKILA 1170
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909128 1171 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1231
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2586-2790 1.04e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 1.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2586 EDLQRSSNALQ--EEKRDLSKEIESLKVSVSQLTRQVTALQEEG-TLGIYHAQLKVK---------EEELQRLSALLSSS 2653
Cdd:COG4913    235 DDLERAHEALEdaREQIELLEPIRELAERYAAARERLAELEYLRaALRLWFAQRRLElleaeleelRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2654 QKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLmvtKENKDLTA 2733
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFA---ALRAEAAA 391

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 2734 QIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSE 2790
Cdd:COG4913    392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDA 448
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1307-2544 1.34e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 54.67  E-value: 1.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1307 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQIN---KQGLEIES----LKTASHEAEVRAESLQQKLESS 1379
Cdd:TIGR01612  540 KEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIKdlfDKYLEIDDeiiyINKLKLELKEKIKNISDKNEYI 619

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1380 QLQIAGLEHLRELQPELDELQKLISEKeedvsyLSGQLREKEAALTKIQTEIIE-QEDLIKALHTQLEMQAKEHDERIKQ 1458
Cdd:TIGR01612  620 KKAIDLKKIIENNNAYIDELAKISPYQ------VPEHLKNKDKIYSTIKSELSKiYEDDIDALYNELSSIVKENAIDNTE 693

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1459 LQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKE------ALKENKSLQEELSLARD-TIEHLTKSLADVESHVSA 1531
Cdd:TIGR01612  694 DKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKnelldiIVEIKKHIHGEINKDLNkILEDFKNKEKELSNKIND 773

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1532 QNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKS------SKIAESSE 1605
Cdd:TIGR01612  774 YAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFmkddflNKVDKFIN 853

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1606 WQEKHKE-LQKEYEILLQSYENVSNEaeriqhvveaVRQEKQELY-GKLRSTEANKKETEKQLQEAEKEMEEMKEKMR-- 1681
Cdd:TIGR01612  854 FENNCKEkIDSEHEQFAELTNKIKAE----------ISDDKLNDYeKKFNDSKSLINEINKSIEEEYQNINTLKKVDEyi 923

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1682 KFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMetllSSNASMKEEVERVKMEYET-LSKKFQSL-MSEKDSLSEEVQ 1759
Cdd:TIGR01612  924 KICENTKESIEKFHNKQNILKEILNKNIDTIKESN----LIEKSYKDKFDNTLIDKINeLDKAFKDAsLNDYEAKNNELI 999

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1760 DLKHQLESNVSKqaNLEATEKHdnQMNVTEEATQSIPGETEDqdslsmstrpacsesvpsensANPAVSE-DVSSHDEIN 1838
Cdd:TIGR01612 1000 KYFNDLKANLGK--NKENMLYH--QFDEKEKATNDIEQKIED---------------------ANKNIPNiEIAIHTSIY 1054

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1839 NYLQQIDQL-KERIAGLEEEKQKNKEFSQTLENERNALLSQIS----TKDGELKlLQEEVSK----MNLLNQQIQEELSR 1909
Cdd:TIGR01612 1055 NIIDEIEKEiGKNIELLNKEILEEAEINITNFNEIKEKLKHYNfddfGKEENIK-YADEINKikddIKNLDQKIDHHIKA 1133

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1910 VTKLKETAEEEKDDLEERLmnqlaelngsigNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK------QQLVKEKTK 1983
Cdd:TIGR01612 1134 LEEIKKKSENYIDEIKAQI------------NDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKniydeiKKLLNEIAE 1201

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1984 VESEirKEYLEKIQGAqkepgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK-ISALERTVKALEFVQTESQKDLEITK 2062
Cdd:TIGR01612 1202 IEKD--KTSLEEVKGI-----NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAyIEDLDEIKEKSPEIENEMGIEMDIKA 1274

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2063 ENLAQAVEHRKKAQAELASFK--VLLDDTQSEAARVLADNLK------LKKELQSNkesvKSQMKQKDEDLERRLEQ-AE 2133
Cdd:TIGR01612 1275 EMETFNISHDDDKDHHIISKKhdENISDIREKSLKIIEDFSEesdindIKKELQKN----LLDAQKHNSDINLYLNEiAN 1350

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2134 EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDstvaqLAAFTKSMSSLQDDRDrvIDEAKKW 2213
Cdd:TIGR01612 1351 IYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDIN-----LEECKSKIESTLDDKD--IDECIKK 1423

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2214 ERKFSDAIQTKEEEI-----RLKEENCSVLK-----DQLRQMSIHMEELKINISRLEHDKQIWESKAQTEvqlQQKVCDT 2283
Cdd:TIGR01612 1424 IKELKNHILSEESNIdtyfkNADENNENVLLlfkniEMADNKSQHILKIKKDNATNDHDFNINELKEHID---KSKGCKD 1500

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2284 LQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEA------DIQNSKFS 2357
Cdd:TIGR01612 1501 EADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKseqkikEIKKEKFR 1580

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2358 YEQLETDLQASRELTSRLHEEINMKEQKMISllsgkeeaiqvaIAELRQQHDKEIKELENLLSQEEEENIVLEEEN-KKA 2436
Cdd:TIGR01612 1581 IEDDAAKNDKSNKAAIDIQLSLENFENKFLK------------ISDIKKKINDCLKETESIEKKISSFSIDSQDTElKEN 1648

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2437 VDKTNQLMETLNAIK--KENIQ-QKAQLDSFVKSMSSLQNDRDRIVGDYQqleerhlSVILEKdqlIQEAAAEN-NKLKE 2512
Cdd:TIGR01612 1649 GDNLNSLQEFLESLKdqKKNIEdKKKELDELDSEIEKIEIDVDQHKKNYE-------IGIIEK---IKEIAIANkEEIES 1718

                         1290      1300      1310
                   ....*....|....*....|....*....|..
gi 1622909128 2513 EIRGLRSHMDDLNSENAKLDAELIQYREDLNQ 2544
Cdd:TIGR01612 1719 IKELIEPTIENLISSFNTNDLEGIDPNEKLEE 1750
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 991-1654 1.49e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.49e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  991 EQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKeiplsesergeveedkenkeysekcvtskcqeieisLKQTISE 1070
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEE------------------------------------LEAELAE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1071 KEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvis 1150
Cdd:COG1196    265 LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE---- 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1151 ppgtdsgehwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENEN 1230
Cdd:COG1196    341 ------------ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1231 IGDQLRQLQIQVRESIdgklpspdqqewcsptpgleeplfkateqhhtqpvlesnlcpdwpshSEDASALQGGTSVAQIK 1310
Cdd:COG1196    409 EEALLERLERLEEELE-----------------------------------------------ELEEALAELEEEEEEEE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1311 AQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKtASHEAEVRAESLQQKLESSQLQIAGLEHLR 1390
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA-ARLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1391 ELQPELDELQKLISEKEEDV-SYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1469
Cdd:COG1196    521 GLAGAVAVLIGVEAAYEAALeAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAA 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1470 PEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEE 1549
Cdd:COG1196    601 VDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1550 RDKLITEMDRSLLENQslsgscESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSN 1629
Cdd:COG1196    681 LEELAERLAEEELELE------EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754

                          650       660
                   ....*....|....*....|....*
gi 1622909128 1630 EAERIQhVVEAVRQEKQELYGKLRS 1654
Cdd:COG1196    755 ELPEPP-DLEELERELERLEREIEA 778
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1074-1634 1.63e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.30  E-value: 1.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1074 ELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTtsntdaSDGDSVALVKETVVISPPG 1153
Cdd:PRK03918   173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLE------KEVKELEELKEEIEELEKE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1154 TDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAI--LKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1231
Cdd:PRK03918   247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELkeLKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1232 GDQLRQLQIQVRESidgklpspdqQEWCSPTPGLEEPLFKATEQHHTQPVLESNLcpdwpSHSEDASALQGGTSVAQIKA 1311
Cdd:PRK03918   327 EERIKELEEKEERL----------EELKKKLKELEKRLEELEERHELYEEAKAKK-----EELERLKKRLTGLTPEKLEK 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1312 QLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINkqglEIESLK----------TASHEAEVRAESLQQKLESSQL 1381
Cdd:PRK03918   392 ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIE----ELKKAKgkcpvcgrelTEEHRKELLEEYTAELKRIEKE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1382 QIAGLEHLRELQPELDELQKLISEKEEDVSY--LSGQLREKEAALTKIQTEIIEQE----DLIKALHTQLEMQ---AKEH 1452
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKKESELIKLkeLAEQLKELEEKLKKYNLEELEKKaeeyEKLKEKLIKLKGEiksLKKE 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1453 DERIKQLQVELCEMKQKPEEIEEE-SRAKQQIQRKLQAALISRKEALKENKSLQE---ELSLARDTIEHLTKSLADVESH 1528
Cdd:PRK03918   548 LEKLEELKKKLAELEKKLDELEEElAELLKELEELGFESVEELEERLKELEPFYNeylELKDAEKELEREEKELKKLEEE 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1529 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSllENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSkIAESSEWQE 1608
Cdd:PRK03918   628 LDKAFEELAETEKRLEELRKELEELEKKYSEE--EYEELREEYLELSRELAGLRAELEELEKRREEIKKT-LEKLKEELE 704

                          570       580
                   ....*....|....*....|....*.
gi 1622909128 1609 KHKELQKEYEILLQSYENVSNEAERI 1634
Cdd:PRK03918   705 EREKAKKELEKLEKALERVEELREKV 730
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1713-2342 2.59e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.58  E-value: 2.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1713 KECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSL-------SEEVQDLKHQLESNV-----SKQANLEATEK 1780
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMadirrreSQSQEDLRNQLQNTVheleaAKCLKEDMLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1781 HDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSShdEINNYLQQIDQ----LKERIAGLEE 1856
Cdd:pfam15921  168 SNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGS--AISKILRELDTeisyLKGRIFPVED 245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1857 EKQKNKEFSQT-----LENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELsrvtklkETAEEEKDDLEERLMNQ 1931
Cdd:pfam15921  246 QLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQL-------EIIQEQARNQNSMYMRQ 318

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1932 LAELNGSIGNYCQDVTDA----QIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKS 2007
Cdd:pfam15921  319 LSDLESTVSQLRSELREAkrmyEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKE 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2008 HAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALefvQTESQKDLEitkeNLAQAVEHRKKAQAELASFKVLLD 2087
Cdd:pfam15921  399 QNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAM---KSECQGQME----RQMAAIQGKNESLEKVSSLTAQLE 471

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2088 DTQsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLE--QAEEKHLKEKKNMQ-EKLDALRREKVHLEETIGE- 2163
Cdd:pfam15921  472 STK-EMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEatNAEITKLRSRVDLKlQELQHLKNEGDHLRNVQTEc 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2164 --IQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVideakkwERKFSDA-IQTKEEEIRLKEENCSVLKD 2240
Cdd:pfam15921  551 eaLKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQL-------EKEINDRrLELQEFKILKDKKDAKIREL 623

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2241 QLRQMSIHMEELKINISRLEHDKQIWESKaqtevQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILK 2320
Cdd:pfam15921  624 EARVSDLELEKVKLVNAGSERLRAVKDIK-----QERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLK 698

                          650       660
                   ....*....|....*....|..
gi 1622909128 2321 DQLTDLSNSLEKCKEQKENLEG 2342
Cdd:pfam15921  699 MQLKSAQSELEQTRNTLKSMEG 720
PTZ00121 PTZ00121
MAEBL; Provisional
 1981-2687 2.72e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.61  E-value: 2.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1981 KTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKdcIRYQEKISALERTVKALEFVQTESQKDLE- 2059
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEE--ARKAEDARKAEEARKAEDAKRVEIARKAEd 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2060 ITKENLAQAVEHRKKAQAELASFKV--------LLDDTQSEAARvLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ 2131
Cdd:PTZ00121  1163 ARKAEEARKAEDAKKAEAARKAEEVrkaeelrkAEDARKAEAAR-KAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2132 AeeKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQD--DRDRVIDE 2209
Cdd:PTZ00121  1242 A--KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADE 1319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2210 AKK---WERKFSDAIQTKEEEIRLKEEnCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQG 2286
Cdd:PTZ00121  1320 AKKkaeEAKKKADAAKKKAEEAKKAAE-AAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKK 1398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2287 ENKELLSQLEETRHLYHNSQN-ELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEAdiqnSKFSYEQLETDL 2365
Cdd:PTZ00121  1399 KAEEDKKKADELKKAAAAKKKaDEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEA----KKKAEEAKKADE 1474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2366 QASRELTSRLHEEINMK---EQKMISLLSGKEEAIQVAiAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQ 2442
Cdd:PTZ00121  1475 AKKKAEEAKKADEAKKKaeeAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2443 LMETLNAIKKENIQQKaqldsfvKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMD 2522
Cdd:PTZ00121  1554 AEELKKAEEKKKAEEA-------KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELK 1626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2523 DLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQlqqnkELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDL 2602
Cdd:PTZ00121  1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA-----EEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA 1701

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2603 SKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKL 2682
Cdd:PTZ00121  1702 KKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI 1781


                   ....*
gi 1622909128 2683 KKELK 2687
Cdd:PTZ00121  1782 EEELD 1786
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2240-2857 2.86e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 2.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2240 DQLRQMSIHMEELKINISRLEHDKQIWES--KAQTEVQLQQKVCDTLQGENKELLSQLEETRHlyHNSQNELAKLESELN 2317
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLRAALRLWFAQRRLELLEAEL--EELRAELARLEAELE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2318 ILKDQLTDLSNSLEKCKEQKENLEGIIRQQ-EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMisllsgkeEA 2396
Cdd:COG4913    313 RLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEF--------AA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2397 IQVAIAELRQQHDKEIKELENLLSQEEEENivleeenKKAVDKTNQLMETLNAIKkeniQQKAQLDSFVKSM-----SSL 2471
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAAL-------RDLRRELRELEAEIASLE----RRKSNIPARLLALrdalaEAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2472 QNDRD--RIVGDYQQLEERH---------------LSVILEKDQLIQEAAA-ENNKLKEEIRGLRSHMDDLNSENAKLDA 2533
Cdd:COG4913    454 GLDEAelPFVGELIEVRPEEerwrgaiervlggfaLTLLVPPEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDP 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2534 EliqyreDLNQVISIKDSQQKQLLEAQLQQNKELknkyakleeklkeseeanedlqrssnalqeekrdlskeiesLKV-S 2612
Cdd:COG4913    534 D------SLAGKLDFKPHPFRAWLEAELGRRFDY-----------------------------------------VCVdS 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2613 VSQLTRQVTALQEEGTL-GIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKkVGEIEDKLKKELKHLH- 2690
Cdd:COG4913    567 PEELRRHPRAITRAGQVkGNGTRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAE-AEERLEALEAELDALQe 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2691 -HDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAqiqsfgrsmsslqnsrdhANEELDELKRKYDASLKE 2769
Cdd:COG4913    646 rREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA------------------LEEQLEELEAELEELEEE 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2770 LAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYLEKLNQQLlskDEQLLHLssQLEDSYNQV-QSFSKAMASLQNER 2848
Cdd:COG4913    708 LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL---EERFAAA--LGDAVERELrENLEERIDALRARL 782


                   ....*....
gi 1622909128 2849 DHLWNELEK 2857
Cdd:COG4913    783 NRAEEELER 791
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
676-1113 2.95e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 2.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  676 AVPDIGQCHQDELERLKSQILELE-LNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLlaq 754
Cdd:PRK02224   177 GVERVLSDQRGSLDQLKAQIEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREEL--- 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  755 vkelsvvTELRAQVRQLEMNLAEAERQRR-FDYESQTAHHNLLT--EQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQ 831
Cdd:PRK02224   254 -------ETLEAEIEDLRETIAETEREREeLAEEVRDLRERLEEleEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  832 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQV------ 905
Cdd:PRK02224   327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFgdapvd 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  906 ----TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK----EQVEEDNEVVSGLKQNYDEmspaglisKE 977
Cdd:PRK02224   407 lgnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVETIEEDRER--------VE 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  978 ELQHEFDLLKKENEQRKRKLQAAlINRKELLQRVSRLEEELANLKDqskkeipLSESERGEVEEDKENKEysekcvtskc 1057
Cdd:PRK02224   479 ELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEE-------LIAERRETIEEKRERAE---------- 540

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128 1058 qeieiSLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLL 1113
Cdd:PRK02224   541 -----ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL 591
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1312-1462 3.07e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 51.08  E-value: 3.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1312 QLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHLRE 1391
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE 90

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622909128 1392 ---LQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1462
Cdd:COG1579     91 yeaLQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2307-2927 3.09e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.10  E-value: 3.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2307 NELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLEtdlQASRELTSRLheeinMKEQKM 2386
Cdd:TIGR04523   26 NIANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILE---QQIKDLNDKL-----KKNKDK 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2387 ISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMET---LNAIKKENIQQKAQLDS 2463
Cdd:TIGR04523   98 INKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLnnkYNDLKKQKEELENELNL 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2464 FVKSMSSLQNDRDRIVGDYQQLEERhLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLN 2543
Cdd:TIGR04523  178 LEKEKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLN 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2544 QVISIKDSQQKQLLEAQL---QQNKELKNKYAKLEEKLKE-SEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQ 2619
Cdd:TIGR04523  257 QLKDEQNKIKKQLSEKQKeleQNNKKIKELEKQLNQLKSEiSDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKI 336

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2620 VTALQEegtlgiyhaQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIED------KLKKELKHLHHDA 2693
Cdd:TIGR04523  337 ISQLNE---------QISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNlesqinDLESKIQNQEKLN 407

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2694 GIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQL 2773
Cdd:TIGR04523  408 QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQK 487

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2774 KEQQGLLNRERHALLSETTFSmdlpeENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQS------FSKAMASLQNE 2847
Cdd:TIGR04523  488 QKELKSKEKELKKLNEEKKEL-----EEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDelnkddFELKKENLEKE 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2848 RDHLWNELEKFR---KSEEGKQRSAAQPATSL-AEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQ 2923
Cdd:TIGR04523  563 IDEKNKEIEELKqtqKSLKKKQEEKQELIDQKeKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNK 642


                   ....
gi 1622909128 2924 LQEY 2927
Cdd:TIGR04523  643 LKQE 646
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2491-2907 3.20e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 3.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2491 SVILEKD--QLIQEAAAENNKLKEEIRGLrshmDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleAQLQQNKELK 2568
Cdd:TIGR02169  137 NVVLQGDvtDFISMSPVERRKIIDEIAGV----AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQL--ERLRREREKA 210

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2569 NKYakleeklkeseeanedlqrssNALQEEKRD-----LSKEIESLKVSVSQLTRQVTALqeegtlgiyhaqlkvkEEEL 2643
Cdd:TIGR02169  211 ERY---------------------QALLKEKREyegyeLLKEKEALERQKEAIERQLASL----------------EEEL 253

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2644 QRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHhdagimrNETETAEERVAELARDLVEMEQKLLM 2723
Cdd:TIGR02169  254 EKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELE-------AEIASLERSIAEKERELEDAEERLAK 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2724 VTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTfsmDLPEEnsl 2803
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE---KLKRE--- 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2804 syLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKfrksEEGKQRSAAqpatslAEVQSLK 2883
Cdd:TIGR02169  401 --INELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK----QEWKLEQLA------ADLSKYE 468

                          410       420
                   ....*....|....*....|....
gi 1622909128 2884 KAMSSLQNDRDRLLKELKNLQQQY 2907
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQREL 492
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2594-3192 3.38e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 3.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2594 ALQEEKRDLSK-----EIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQ 2668
Cdd:TIGR02168  217 ELKAELRELELallvlRLEELREELEELQEELKEAEEE--LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2669 KEAAKKVGEIEdKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNS 2748
Cdd:TIGR02168  295 NEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2749 RDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSEttfsmdlpeenslsyLEKLNQQLLSKDEQLLhlSSQLE 2828
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDR---------------RERLQQEIEELLKKLE--EAELK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2829 DSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYL 2908
Cdd:TIGR02168  437 ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQS 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2909 QINQ------EITELRP---------LKAQLQEYQDKTKTFQIM-QEELRQENLSWQH--ELHQLRMEKSSWEIHERRMK 2970
Cdd:TIGR02168  517 GLSGilgvlsELISVDEgyeaaieaaLGGRLQAVVVENLNAAKKaIAFLKQNELGRVTflPLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2971 -EQYLMAISDKDQQVSHLQNLIRELRSSSS------QAQPLKVQYQRQASPET----SASPDGSQN----------LIYE 3029
Cdd:TIGR02168  597 iEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvddldNALELAKKLRPGYRIVTldgdLVRPGGVITggsaktnssiLERR 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 3030 TEL--LRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAVS 3107
Cdd:TIGR02168  677 REIeeLEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 3108 KEKgpLNIDVAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERD----------------- 3170
Cdd:TIGR02168  757 TEL--EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlrerleslerria 834

                          650       660
                   ....*....|....*....|....*.
gi 1622909128 3171 ----QRVAAENALSLAEEQIRRLEHS 3192
Cdd:TIGR02168  835 aterRLEDLEEQIEELSEDIESLAAE 860
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 473-1247 3.52e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 3.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  473 ASLQKRVVELENEKGAL--LLSSIELEELKAENEKLSSQITLLEAQNRIGEADREVSEISIvDDANKRSSSTEESgQDVL 550
Cdd:TIGR02168  209 AEKAERYKELKAELRELelALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL-EELRLEVSELEEE-IEEL 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  551 ENTFSQKHKELSVLLLEMKEAQEEIAFLK---LQLQGKRAEEGDHEVLDQKEMKQMEGEgiapikmevfLEDTGQNFPLM 627
Cdd:TIGR02168  287 QKELYALANEISRLEQQKQILRERLANLErqlEELEAQLEELESKLDELAEELAELEEK----------LEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  628 PNEESSLPAVEKEQASTEHQNRTsEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQ- 706
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEl 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  707 EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQRRFDY 786
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  787 ESQTAHHNLLTEQIH-----SLSIEA----KSKDVKIEVLQNELDDVQLQfsEQSTLIRSL--------QSQLQNKESEV 849
Cdd:TIGR02168  516 SGLSGILGVLSELISvdegyEAAIEAalggRLQAVVVENLNAAKKAIAFL--KQNELGRVTflpldsikGTEIQGNDREI 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  850 LEGAERVRHISSKVEELSQALSqkeleiaKMDQLLLEKKRDVETLQQTIEE------------KDQQVTEISFSMTEKMV 917
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFDPKLR-------KALSYLLGGVLVVDDLDNALELakklrpgyrivtLDGDLVRPGGVITGGSA 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  918 QLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEdnevVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKL 997
Cdd:TIGR02168  667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAE----LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  998 QAalinrkeLLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEiSLKQTISEKEVELEH 1077
Cdd:TIGR02168  743 EQ-------LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK-ALREALDELRAELTL 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1078 IRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISppGTDSG 1157
Cdd:TIGR02168  815 LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEE--ALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1158 EHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQ 1237
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972

                          810
                   ....*....|
gi 1622909128 1238 LQIQVRESID 1247
Cdd:TIGR02168  973 RLKRLENKIK 982
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2128-2771 3.68e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 3.68e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2128 RLEQAEEKHLKEKKNMQEKLDALRRE---KVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRD 2204
Cdd:PRK03918   159 DYENAYKNLGEVIKEIKRRIERLEKFikrTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2205 RvIDEAKKWERKFSDAIQTKEEEIRLKEEncsvlkdQLRQMSIHMEELKINISRLEHDKQIWEskaqtevqlqqkvcdtl 2284
Cdd:PRK03918   239 E-IEELEKELESLEGSKRKLEEKIRELEE-------RIEELKKEIEELEEKVKELKELKEKAE----------------- 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2285 qgENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEAdIQNSKFSYEQLETD 2364
Cdd:PRK03918   294 --EYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE-LEERHELYEEAKAK 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2365 LQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENIVLeeenKKAVDKTNQLM 2444
Cdd:PRK03918   371 KEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITA----RIGELKKEIKELKKAIEEL----KKAKGKCPVCG 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2445 ETLNAIKKENIqqkaqLDSFVKSMSSLQNDRDRIVGDYQQLEERhlSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2524
Cdd:PRK03918   443 RELTEEHRKEL-----LEEYTAELKRIEKELKEIEEKERKLRKE--LRELEKVLKKESELIKLKELAEQLKELEEKLKKY 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2525 NSENAKLDAEliQYREDLNQVISIKDSQQKqlLEAQLQQNKELKNKYAKleeklkeseeanedLQRSSNALQEEKRDLSK 2604
Cdd:PRK03918   516 NLEELEKKAE--EYEKLKEKLIKLKGEIKS--LKKELEKLEELKKKLAE--------------LEKKLDELEEELAELLK 577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2605 EIESLKV-SVSQLTRQVTALQEegtlgIYHAQLKVK--EEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIED- 2680
Cdd:PRK03918   578 ELEELGFeSVEELEERLKELEP-----FYNEYLELKdaEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEEl 652

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2681 ----------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLlmvtKENKDLTAQIQSFGRSMSSLqnsrd 2750
Cdd:PRK03918   653 ekkyseeeyeELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERV----- 723

                          650       660
                   ....*....|....*....|.
gi 1622909128 2751 hanEELDELKRKYDASLKELA 2771
Cdd:PRK03918   724 ---EELREKVKKYKALLKERA 741
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1310-1776 3.88e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 3.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1310 KAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHL 1389
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1390 -----------RELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQ 1458
Cdd:TIGR04523  203 lsnlkkkiqknKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1459 LQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENksLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDR 1538
Cdd:TIGR04523  283 IKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEE--IQNQISQNNKIISQLNEQISQLKKELTNSESENSE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1539 VLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLAL--------------EGLTEDKEKLVKEIESLKSSKIAESS 1604
Cdd:TIGR04523  361 KQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIqnqeklnqqkdeqiKKLQQEKELLEKEIERLKETIIKNNS 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1605 EWQE----------KHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEME 1674
Cdd:TIGR04523  441 EIKDltnqdsvkelIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1675 EMKEKMRKFAKSKQQKILELEEENDRLRAEvhpAGGTAKECMETLLSSNasmKEEVERVKMEYETLSKKFQSLMSEKDSL 1754
Cdd:TIGR04523  521 SLKEKIEKLESEKKEKESKISDLEDELNKD---DFELKKENLEKEIDEK---NKEIEELKQTQKSLKKKQEEKQELIDQK 594

                          490       500
                   ....*....|....*....|..
gi 1622909128 1755 SEEVQDLKHQLESNVSKQANLE 1776
Cdd:TIGR04523  595 EKEKKDLIKEIEEKEKKISSLE 616
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 346-1126 4.02e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.81  E-value: 4.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  346 HLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQL 425
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  426 -------EDQLQQKSKEISQFlnRLPLQQHETASQ---TCFPDVYNEGTQAVTEENIAS----------LQKRVVELENE 485
Cdd:pfam15921  155 eaakclkEDMLEDSNTQIEQL--RKMMLSHEGVLQeirSILVDFEEASGKKIYEHDSMStmhfrslgsaISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  486 ----KGALLLSSIELEELKAENEKlSSQITLLEAQNRIGEADREvSEISIVDDANKRSS--STEESGQDVLENTFSQKHK 559
Cdd:pfam15921  233 isylKGRIFPVEDQLEALKSESQN-KIELLLQQHQDRIEQLISE-HEVEITGLTEKASSarSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  560 ELSVLLLEMKEAQEEIAFLKLQL-QGKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDTGQNFPLMPNEESSLPAVE 638
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRSELrEAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKRE 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  639 KEQASTEHQNR------TSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQIlelelnfhkaqeiyeKN 712
Cdd:pfam15921  391 KELSLEKEQNKrlwdrdTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI---------------QG 455

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  713 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSvvTELRAQVRQLEMNLAEAERQR-RFDYESQTA 791
Cdd:pfam15921  456 KNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLT--ASLQEKERAIEATNAEITKLRsRVDLKLQEL 533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  792 HHnLLTEQIHslsieakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS 871
Cdd:pfam15921  534 QH-LKNEGDH------------LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIN 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  872 QKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKM---VQLNEEKFSLGVEIKTLKEQLNLLSraeeakk 948
Cdd:pfam15921  601 DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLS------- 673

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  949 eqveEDNEVvsgLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELAnlkdqskke 1028
Cdd:pfam15921  674 ----EDYEV---LKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQIT--------- 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1029 iplseSERGEVEEDKENKEYSEKCVTSKCQEIEIsLKQTISEKEVELEHIRKDlEEKMAAE-EQLQALVKEMNQTLQDKT 1107
Cdd:pfam15921  738 -----AKRGQIDALQSKIQFLEEAMTNANKEKHF-LKEEKNKLSQELSTVATE-KNKMAGElEVLRSQERRLKEKVANME 810

                          810
                   ....*....|....*....
gi 1622909128 1108 NQIDLLQAEISENQVIIQK 1126
Cdd:pfam15921  811 VALDKASLQFAECQDIIQR 829
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1470-1712 5.39e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 5.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1470 PEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEE 1549
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1550 RDKLITEMDRsLLENQSLSGSCESLKLALEGltEDKEKLVKEIESLKSSkiaessewQEKHKELQKEYEILLQSYENVSN 1629
Cdd:COG4942     99 LEAQKEELAE-LLRALYRLGRQPPLALLLSP--EDFLDAVRRLQYLKYL--------APARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1630 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAG 1709
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247


                   ...
gi 1622909128 1710 GTA 1712
Cdd:COG4942    248 FAA 250
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1418-2912 5.54e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 52.75  E-value: 5.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1418 REKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAAL--ISRK 1495
Cdd:TIGR01612  540 KEIEAGLKESYELAKNWKKLIHEIKKELE----EENEDSIHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIknISDK 615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1496 -EALKENKSLQEELSLARDTIEHLTK-SLADVESHVSAQNKEKDRVLGRLA-LLQEERDKLITEMDRSLLENQSLSgsce 1572
Cdd:TIGR01612  616 nEYIKKAIDLKKIIENNNAYIDELAKiSPYQVPEHLKNKDKIYSTIKSELSkIYEDDIDALYNELSSIVKENAIDN---- 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1573 slklaleglTEDKEKLvkeiESLKSSKIAESSEWQEKHKELQKEYeilLQSYENVSNEAERIqhVVEAVRQEKQELYGKL 1652
Cdd:TIGR01612  692 ---------TEDKAKL----DDLKSKIDKEYDKIQNMETATVELH---LSNIENKKNELLDI--IVEIKKHIHGEINKDL 753

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1653 RSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskQQKILELEEE-NDRlraevhpaggtakecmetllSSNASMKEEve 1731
Cdd:TIGR01612  754 NKILEDFKNKEKELSNKINDYAKEKDELNKY----KSKISEIKNHyNDQ--------------------INIDNIKDE-- 807

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1732 RVKMEYETLSKKFQSLMSEKDSLSE---EVQDLKHQLESNVSKQANLEAT--EKHDNQMNVTEEATQSIPGETEDQDSLS 1806
Cdd:TIGR01612  808 DAKQNYDKSKEYIKTISIKEDEIFKiinEMKFMKDDFLNKVDKFINFENNckEKIDSEHEQFAELTNKIKAEISDDKLND 887

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1807 MSTRPACSESVPSE-NSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKE---------------------- 1863
Cdd:TIGR01612  888 YEKKFNDSKSLINEiNKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEilnknidtikesnlieksykdk 967

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1864 FSQTLENERNAL--------LSQISTKDGEL----KLLQEEV--SKMNLLNQQIQEELSRVTKLketaEEEKDDLEERLM 1929
Cdd:TIGR01612  968 FDNTLIDKINELdkafkdasLNDYEAKNNELikyfNDLKANLgkNKENMLYHQFDEKEKATNDI----EQKIEDANKNIP 1043

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1930 NQLAELNGSIGNYCQDVTDAQIKN-ELLESE-MKNLKKCVSELEEEKQQL----VKEKTKVESEIRKEYLEKIQGAQKEP 2003
Cdd:TIGR01612 1044 NIEIAIHTSIYNIIDEIEKEIGKNiELLNKEiLEEAEINITNFNEIKEKLkhynFDDFGKEENIKYADEINKIKDDIKNL 1123

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2004 GNK--SHAKELQELLKEKQQEVKQLQKdciryqeKISALERTVKALefVQTESQKDLEITKENLAQAVEHRKKAQAELas 2081
Cdd:TIGR01612 1124 DQKidHHIKALEEIKKKSENYIDEIKA-------QINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEI-- 1192

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2082 fKVLLddtqSEAARVLADNLKLKK----ELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKV 2155
Cdd:TIGR01612 1193 -KKLL----NEIAEIEKDKTSLEEvkgiNLSYGKNLGKLFLEKIDEEKKKseHMIKAMEAYIEDLDEIKEKSPEIENEMG 1267

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2156 HLEETIGEIQV--TLNKKDKEIQQVQENLDSTVAQLAafTKSMSSLQDD-RDRVIDEAKKWERKFSDAIQTKEEEIRLKE 2232
Cdd:TIGR01612 1268 IEMDIKAEMETfnISHDDDKDHHIISKKHDENISDIR--EKSLKIIEDFsEESDINDIKKELQKNLLDAQKHNSDINLYL 1345

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2233 ENCSVLkdqlrqmsihmeelkINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyhNSQNELAKL 2312
Cdd:TIGR01612 1346 NEIANI---------------YNILKLNKIKKIID-------------------EVKEYTKEIEENNK---NIKDELDKS 1388

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2313 ESELNILKDQLtdlsnSLEKCKEQKE------NLEGIIrQQEADIQNSKFSYE-QLETDLQASRELT---SRLHEEINMK 2382
Cdd:TIGR01612 1389 EKLIKKIKDDI-----NLEECKSKIEstlddkDIDECI-KKIKELKNHILSEEsNIDTYFKNADENNenvLLLFKNIEMA 1462

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2383 EQKMISLLSGKEEaiqvaiaELRQQHDKEIKELENLLSQEEEENIVLEEeNKKAVDKTNQLMETLNAIKKENIQQKAQLd 2462
Cdd:TIGR01612 1463 DNKSQHILKIKKD-------NATNDHDFNINELKEHIDKSKGCKDEADK-NAKAIEKNKELFEQYKKDVTELLNKYSAL- 1533

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2463 SFVKSMSSLQNDRDRIVGDYQQLE----------ERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLD 2532
Cdd:TIGR01612 1534 AIKNKFAKTKKDSEIIIKEIKDAHkkfileaeksEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKIS 1613

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2533 AELIQYREDLNQVISIK--------DSQQKQLLEAQLQQN------KELKNKYAKLEEKLKESEEANEDLQRSSNALQEE 2598
Cdd:TIGR01612 1614 DIKKKINDCLKETESIEkkissfsiDSQDTELKENGDNLNslqeflESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQH 1693

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2599 KRDLS---------------KEIESLKVSVSQLTRQVTA---------LQEEGTLGIYHAQLKVKEEELQRLSALLSS-- 2652
Cdd:TIGR01612 1694 KKNYEigiiekikeiaiankEEIESIKELIEPTIENLISsfntndlegIDPNEKLEEYNTEIGDIYEEFIELYNIIAGcl 1773

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2653 ---SQKRIT--ELEEELVCVQKEAAKKVgEIEDKLKKELKHLhhdagimrnetetaeeRVAELARDLVEMEQKLLMV--- 2724
Cdd:TIGR01612 1774 etvSKEPITydEIKNTRINAQNEFLKII-EIEKKSKSYLDDI----------------EAKEFDRIINHFKKKLDHVndk 1836

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2725 -TKENKDLTAQIQSFGRSMSSLQNSRDHaNEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENS- 2802
Cdd:TIGR01612 1837 fTKEYSKINEGFDDISKSIENVKNSTDE-NLLFDILNKTKDAYAGIIGKKYYSYKDEAEKIFINISKLANSINIQIQNNs 1915

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2803 -LSYLEKLNQQLLSkdeqllHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSA---------AQP 2872
Cdd:TIGR01612 1916 gIDLFDNINIAILS------SLDSEKEDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQdtlniifenQQL 1989

                         1610      1620      1630      1640
                   ....*....|....*....|....*....|....*....|
gi 1622909128 2873 ATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQ 2912
Cdd:TIGR01612 1990 YEKIQASNELKDTLSDLKYKKEKILNDVKLLLHKFDELNK 2029
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1310-1514 6.11e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 6.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1310 KAQLKEIETEKEKLELKISsttsELTKKSEEVFQLQDQINKQGLEIESLKTAShEAEVRAESLQQKLESSQLQiagLEHL 1389
Cdd:COG4913    609 RAKLAALEAELAELEEELA----EAEERLEALEAELDALQERREALQRLAEYS-WDEIDVASAEREIAELEAE---LERL 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1390 RELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEmKQK 1469
Cdd:COG4913    681 DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE----AAEDLARLELRALLE-ERF 755

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1622909128 1470 PEEIEEESRakQQIQRKLQAaliSRKEALKENKSLQEELSLARDT 1514
Cdd:COG4913    756 AAALGDAVE--RELRENLEE---RIDALRARLNRAEEELERAMRA 795
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1578-2184 6.85e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.94  E-value: 6.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1578 LEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1657
Cdd:TIGR04523  129 LEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKK 208

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1658 nKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDrlraevhpaggTAKECMETLLSSNASMKEEVERVKMEY 1737
Cdd:TIGR04523  209 -KIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS-----------NTQTQLNQLKDEQNKIKKQLSEKQKEL 276

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1738 ETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMStrpacsesv 1817
Cdd:TIGR04523  277 EQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQL--------- 347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1818 psENSANPAVSEDVSSHDEINNYLQQIDQLKEriagleeEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMN 1897
Cdd:TIGR04523  348 --KKELTNSESENSEKQRELEEKQNEIEKLKK-------ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQ 418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1898 LLNQQIQEELSRVTKLKETAEEEKDDLEerlmNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKkcvSELEEEKQQL 1977
Cdd:TIGR04523  419 QEKELLEKEIERLKETIIKNNSEIKDLT----NQDSVKELIIKNLDNTRESLETQLKVLSRSINKIK---QNLEQKQKEL 491

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1978 VKEktkvESEIRKEYLEKIQGAQKepgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFvqtesqkd 2057
Cdd:TIGR04523  492 KSK----EKELKKLNEEKKELEEK-------VKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF-------- 552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2058 lEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLErRLEQAEEKHL 2137
Cdd:TIGR04523  553 -ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELE-KAKKENEKLS 630

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909128 2138 KEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2184
Cdd:TIGR04523  631 SIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1731-2346 7.06e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 7.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1731 ERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEAteKHDNQMNVTEEATQSIPGETEDQDSLSMSTR 1810
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEA--ELEELRLELEELELELEEAQAEEYELLAELA 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1811 PACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQ 1890
Cdd:COG1196    299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1891 EEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELngsignycQDVTDAQIKNELLESEMKNLKKCVSEL 1970
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL--------EELEEALAELEEEEEEEEEALEEAAEE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1971 EEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISA--LERTVKALE 2048
Cdd:COG1196    451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrgLAGAVAVLI 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2049 FVQTESQKDLEITKENLAQAVeHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKsqmkqkdEDLERR 2128
Cdd:COG1196    531 GVEAAYEAALEAALAAALQNI-VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA-------IGAAVD 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2129 LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2208
Cdd:COG1196    603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2209 EAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGEN 2288
Cdd:COG1196    683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909128 2289 KELLSQLEETRhlyhnsqNELAKLES-------ELNILKDQLTDLSNSLEKCKEQKENLEGIIRQ 2346
Cdd:COG1196    763 EELERELERLE-------REIEALGPvnllaieEYEELEERYDFLSEQREDLEEARETLEEAIEE 820
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
987-1518 8.85e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 8.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  987 KKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDqskkEIPLSESERGEVEEDKEN-----KEYSEKCVTSKCQEIE 1061
Cdd:PRK02224   184 DQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDE----EIERYEEQREQARETRDEadevlEEHEERREELETLEAE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1062 IS-LKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTL-------QDKTNQIDLLQAEISENQviiQKLTTSNTD 1133
Cdd:PRK02224   260 IEdLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAglddadaEAVEARREELEDRDEELR---DRLEECRVA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1134 ASDGDSVAlvketvvisppgtDSGEHWKPELEEKILALEKEKEQLQKKLQ---EALTSRKAILKKAQEKERHLREELKQQ 1210
Cdd:PRK02224   337 AQAHNEEA-------------ESLREDADDLEERAEELREEAAELESELEearEAVEDRREEIEELEEEIEELRERFGDA 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1211 KDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESID-----------GKLPSPDQQEWCSP-TPGLEEPLFKATEqhht 1278
Cdd:PRK02224   404 PVDLGNAEDFLEELREERDELREREAELEATLRTARErveeaealleaGKCPECGQPVEGSPhVETIEEDRERVEE---- 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1279 qpvLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESL 1358
Cdd:PRK02224   480 ---LEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1359 KTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVsylsGQLREKEAALTKIQTEIIEQEDLI 1438
Cdd:PRK02224   557 REAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEI----ERLREKREALAELNDERRERLAEK 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1439 KALHTQLEmqAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHL 1518
Cdd:PRK02224   633 RERKRELE--AEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEAL 710
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2344-3103 9.66e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 9.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2344 IRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEqKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS--- 2420
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREYEGYELLKEKEALERQKEAIERQLAsle 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2421 QEEEENIVLEEENKKAVDKTNQLMETLNA-IKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsvilEKDQL 2499
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKkIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE-------DAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2500 IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNqvisikdsqqkqLLEAQLQQ----NKELKNKYAKLE 2575
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELE------------DLRAELEEvdkeFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2576 EKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYhaQLKVKEEELQRLSALLSSSQK 2655
Cdd:TIGR02169  392 EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAL--EIKKQEWKLEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2656 RITELEEELVCVQKEAAKKVGEIeDKLKKELKHLHHDAGIMRNETETAEER---VAELARDLVEMEQKLLmvtkenkdLT 2732
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQREL-AEAEAQARASEERVRGGRAVEEVLKASiqgVHGTVAQLGSVGERYA--------TA 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2733 AQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPE-----ENSLSY-- 2805
Cdd:TIGR02169  541 IEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEfdpkyEPAFKYvf 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2806 -----LEKL--------NQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQrsaaqp 2872
Cdd:TIGR02169  621 gdtlvVEDIeaarrlmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ------ 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2873 atslAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEIT----ELRPLKAQLQEYQDKTKTFQIMQEELRQENLSW 2948
Cdd:TIGR02169  695 ----SELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEklkeRLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2949 QHELHQLRMEKSSWEIHERRMKEQYLMAISDK-DQQVSHLQNLIRELRSSSSQAQPLKVQYQrqaspetsaspDGSQNLI 3027
Cdd:TIGR02169  771 EEDLHKLEEALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTLEKEYLE-----------KEIQELQ 839

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128 3028 YETELLRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQEL 3103
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1304-2225 1.03e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 51.71  E-value: 1.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1304 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLE-------IESLKTASHEAEVRAESLQQKL 1376
Cdd:pfam01576  103 QHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKErklleerISEFTSNLAEEEEKAKSLSKLK 182

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1377 ESSQLQIAGLE-HLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE- 1454
Cdd:pfam01576  183 NKHEAMISDLEeRLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNa 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1455 --RIKQLQVELCEMkQKPEEIEEESRAKQQIQRKlqaALISRKEALKenKSLQEELSLARDTIEHLTKSLADVESHVSAQ 1532
Cdd:pfam01576  263 lkKIRELEAQISEL-QEDLESERAARNKAEKQRR---DLGEELEALK--TELEDTLDTTAAQQELRSKREQEVTELKKAL 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1533 NKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEgltEDKEKLVKEIESLKSSKI----------AE 1602
Cdd:pfam01576  337 EEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALE---SENAELQAELRTLQQAKQdsehkrkkleGQ 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1603 SSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRK 1682
Cdd:pfam01576  414 LQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQ 493

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1683 FAKSKQQKILELEEEND-RLRAEVHPAGGTAK------------ECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMS 1749
Cdd:pfam01576  494 LEDERNSLQEQLEEEEEaKRNVERQLSTLQAQlsdmkkkleedaGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEK 573

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1750 EKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQ--------DSLSMSTRPACSES----- 1816
Cdd:pfam01576  574 TKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRaeaearekETRALSLARALEEAleake 653

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1817 -VPSENSANPAVSED-VSSHDEINNYL-----------QQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQIStKD 1883
Cdd:pfam01576  654 eLERTNKQLRAEMEDlVSSKDDVGKNVhelerskraleQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFE-RD 732

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1884 GELKLLQEEVSKMNLLNQ--QIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSigNYCQDVTDAQIKNelLESEMK 1961
Cdd:pfam01576  733 LQARDEQGEEKRRQLVKQvrELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAA--NKGREEAVKQLKK--LQAQMK 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1962 NLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALE 2041
Cdd:pfam01576  809 DLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLE 888

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2042 RTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQK 2121
Cdd:pfam01576  889 ARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSS 968

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2122 DEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeIQVTLNKKDKEiqQVQENLDSTVAQLAAFTKSMSSLQD 2201
Cdd:pfam01576  969 IAALEAKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVL--LQVEDERRHAD--QYKDQAEKGNSRMKQLKRQLEEAEE 1044

                          970       980
                   ....*....|....*....|....
gi 1622909128 2202 DRDRVIDEAKKWERKFSDAIQTKE 2225
Cdd:pfam01576 1045 EASRANAARRKLQRELDDATESNE 1068
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
704-909 1.03e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.56  E-value: 1.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  704 KAQEIYEKNLDEKAKEISNLNQLIEEFKKNADnnssaFTALSEERDQLLAQVkelsvvTELRAQVRQLEMNLAEAERQRR 783
Cdd:COG3206    175 KALEFLEEQLPELRKELEEAEAALEEFRQKNG-----LVDLSEEAKLLLQQL------SELESQLAEARAELAEAEARLA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  784 FDYESQTAHHNLLTEQIHSLSIEAKSKdvKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRH----- 858
Cdd:COG3206    244 ALRAQLGSGPDALPELLQSPVIQQLRA--QLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILAsleae 321

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128  859 ---ISSKVEELSQALSQKELEIAKMDQL---LLEKKRDVETLQQTIEEKDQQVTEIS 909
Cdd:COG3206    322 leaLQAREASLQAQLAQLEARLAELPELeaeLRRLEREVEVARELYESLLQRLEEAR 378
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1727-2375 1.10e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.66  E-value: 1.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1727 KEEVERVKMEYE-----------------------------TLSKKFQSLMSEKDSL-------SEEVQDLKHQLESNV- 1769
Cdd:pfam15921   73 KEHIERVLEEYShqvkdlqrrlnesnelhekqkfylrqsviDLQTKLQEMQMERDAMadirrreSQSQEDLRNQLQNTVh 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1770 ----SKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSShdEINNYLQQID 1845
Cdd:pfam15921  153 eleaAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGS--AISKILRELD 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1846 Q----LKERIAGLEEEKQKNKEFSQT-----LENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELsrvtklkET 1916
Cdd:pfam15921  231 TeisyLKGRIFPVEDQLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQL-------EI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1917 AEEEKDDLEERLMNQLAELNGSIGNYCQDVTDA----QIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1992
Cdd:pfam15921  304 IQEQARNQNSMYMRQLSDLESTVSQLRSELREAkrmyEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLL 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1993 -----------LEKIQGAQ---KEPGNKSHAKELQELLKEKQQEV-------KQLQKDCI-RYQEKISALERTVKALEFV 2050
Cdd:pfam15921  384 adlhkrekelsLEKEQNKRlwdRDTGNSITIDHLRRELDDRNMEVqrleallKAMKSECQgQMERQMAAIQGKNESLEKV 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2051 QTESQKdLEITKENLAQAVEHRKKAQAELASFKVLLDD--------------TQSEAARVLAD-NLKLK----------- 2104
Cdd:pfam15921  464 SSLTAQ-LESTKEMLRKVVEELTAKKMTLESSERTVSDltaslqekeraieaTNAEITKLRSRvDLKLQelqhlknegdh 542

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2105 -KELQSNKESVKSQMKQKDEDLErRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK----KDKEIQQVQ 2179
Cdd:pfam15921  543 lRNVQTECEALKLQMAEKDKVIE-ILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilKDKKDAKIR 621

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2180 EnLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHME--------E 2251
Cdd:pfam15921  622 E-LEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMEtttnklkmQ 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2252 LKINISRLEHDKQIWESKA-------------QTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNI 2318
Cdd:pfam15921  701 LKSAQSELEQTRNTLKSMEgsdghamkvamgmQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELST 780

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 2319 LKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRL 2375
Cdd:pfam15921  781 VATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRL 837
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1308-2155 1.21e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.59  E-value: 1.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1308 QIKAQLKEIETEKEKLELKiSSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLES----SQLQI 1383
Cdd:TIGR00606  225 QITSKEAQLESSREIVKSY-ENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1384 AGLEHLR------------ELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1451
Cdd:TIGR00606  304 NDLYHNHqrtvrekerelvDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1452 HDERIKQLQVELCEMKQkpEEIEEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLARDTIEHLTKSLADVESHVSA 1531
Cdd:TIGR00606  384 RGPFSERQIKNFHTLVI--ERQEDEAKTAAQLCADLQSKERLKQEQADE---IRDEKKGLGRTIELKKEILEKKQEELKF 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1532 QNKEKDRVLGrlallqeerdklitEMDRSLLENQSLSGSCESLKLALE-GLTEDKEKLVKEIESLKSSKIAESSEWQEKH 1610
Cdd:TIGR00606  459 VIKELQQLEG--------------SSDRILELDQELRKAERELSKAEKnSLTETLKKEVKSLQNEKADLDRKLRKLDQEM 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1611 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLrSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQk 1690
Cdd:TIGR00606  525 EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLL-GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELAS- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1691 ileLEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEV--ERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESN 1768
Cdd:TIGR00606  603 ---LEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESdlERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSC 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1769 VSKQANLEATEKHDNQM-NVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQL 1847
Cdd:TIGR00606  680 CPVCQRVFQTEAELQEFiSDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1848 KERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQE-ELSRVTKLKETAEEEKDDLEE 1926
Cdd:TIGR00606  760 IQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGsDLDRTVQQVNQEKQEKQHELD 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1927 RLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNK 2006
Cdd:TIGR00606  840 TVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLE 919

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2007 SHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKEN--------LAQAVEHRKKAQAE 2078
Cdd:TIGR00606  920 KDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETelntvnaqLEECEKHQEKINED 999

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2079 LASFKVLLdDTQSEAARVLADNLKLKK---ELQSNKESVKSQMKQKDEDLERRLEQAEEKhlkekknMQEKLDALRREKV 2155
Cdd:TIGR00606 1000 MRLMRQDI-DTQKIQERWLQDNLTLRKrenELKEVEEELKQHLKEMGQMQVLQMKQEHQK-------LEENIDLIKRNHV 1071
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1309-1704 1.35e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.17  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1309 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKtaSHEAEVRAESLQQKLESSQlqiaglEH 1388
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN--NQKEQDWNKELKSELKNQE------KK 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1389 LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQVELCEMKQ 1468
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNLESQINDLES 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1469 KPEEIEEESrakQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQE 1548
Cdd:TIGR04523  399 KIQNQEKLN---QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1549 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKEL-QKEYEILLQSYENV 1627
Cdd:TIGR04523  476 SINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIsDLEDELNKDDFELK 555

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 1628 SNEaeriqhvVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1704
Cdd:TIGR04523  556 KEN-------LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKE 625
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2112-2819 1.41e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 1.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2112 ESVKSQMKQKDEDLERRLEQAEEKHLKEK--------------KNMQEKLDAL----RREKVHLEETIGEIQVTLNKKDK 2173
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEKQKfylrqsvidlqtklQEMQMERDAMadirRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2174 EIQQVQENLDSTVAQLAAFTKSMSS----LQDDRDRVIDEAKKWERKFSDAIQTKEEEIRlkeENCSVLKDQLRQMSIHM 2249
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLShegvLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---SLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2250 EELKINISRLEHDKQIWESKAQTEVQL----QQKVCDTLQGENKELLSQLEETRHlyhNSQNELAKLESELNILKDQLTD 2325
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNKIELllqqHQDRIEQLISEHEVEITGLTEKAS---SARSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2326 lSNSLEKCkeQKENLEGIIRQQEADIQNSKFSYEQLETDLQ-----ASRELTSRLHEEINMKE---------QKMISLLS 2391
Cdd:pfam15921  311 -QNSMYMR--QLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlANSELTEARTERDQFSQesgnlddqlQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2392 GKEEAIQ-----------------VAIAELRQQHDK---EIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIK 2451
Cdd:pfam15921  388 KREKELSlekeqnkrlwdrdtgnsITIDHLRRELDDrnmEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLT 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2452 KENIQQKAQLDSFVKSMSSLQ---NDRDRIVGDYQqleerhlSVILEKDQLIQEAAAENNKLK-------EEIRGLRSHM 2521
Cdd:pfam15921  468 AQLESTKEMLRKVVEELTAKKmtlESSERTVSDLT-------ASLQEKERAIEATNAEITKLRsrvdlklQELQHLKNEG 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2522 DDLNSENAKLDAELIQYREDlNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSnaLQEEKRD 2601
Cdd:pfam15921  541 DHLRNVQTECEALKLQMAEK-DKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFK--ILKDKKD 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2602 lsKEIESLKVSVSQLTRQVTALQEEGTLGIyHAQLKVKEEELQRLSALlSSSQKRITELEEELVCVQKEAAKKVGEIE-- 2679
Cdd:pfam15921  618 --AKIRELEARVSDLELEKVKLVNAGSERL-RAVKDIKQERDQLLNEV-KTSRNELNSLSEDYEVLKRNFRNKSEEMEtt 693

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2680 -DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDE 2758
Cdd:pfam15921  694 tNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNK 773

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622909128 2759 LKRKYDASLKELAQLKEQQGLLnRERHALLSETTFSMDLP-EENSLSYLEklNQQLLSKDEQ 2819
Cdd:pfam15921  774 LSQELSTVATEKNKMAGELEVL-RSQERRLKEKVANMEVAlDKASLQFAE--CQDIIQRQEQ 832
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 975-1777 1.50e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  975 SKEELQHEFDLLKKENEQRKRKLQAaliNRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVT 1054
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISE---LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKE 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1055 SKCQEIEISLKQTISE---KEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQI-------DLLQAEISENQVII 1124
Cdd:TIGR02169  315 RELEDAEERLAKLEAEidkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELeevdkefAETRDELKDYREKL 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1125 QKLTtSNTDASDGDSVALVKETVVISPPGTDSGEHWKpELEEKILALEKEKEQLQKKLQEA---LTSRKAILKKAQEKER 1201
Cdd:TIGR02169  395 EKLK-REINELKRELDRLQEELQRLSEELADLNAAIA-GIEAKINELEEEKEDKALEIKKQewkLEQLAADLSKYEQELY 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1202 HLREELKQQKDDYNRLQEQFDEQSKenenigdqlrQLQIQVRESIDGKLPSPDQQEWCSPTPGLEEPLFKATEQHhtQPV 1281
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAEA----------QARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERY--ATA 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1282 LES-------NLCPDWPSHSEDASAL----QGGTS----VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQlqd 1346
Cdd:TIGR02169  541 IEVaagnrlnNVVVEDDAVAKEAIELlkrrKAGRAtflpLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFK--- 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1347 QINKQGLEIESLKTA-SHEAEVRAESLQQKL-ESSQLQIAGleHLRELQPELDELQKlisekEEDVSYLSGQLREKEAAL 1424
Cdd:TIGR02169  618 YVFGDTLVVEDIEAArRLMGKYRMVTLEGELfEKSGAMTGG--SRAPRGGILFSRSE-----PAELQRLRERLEGLKREL 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1425 TKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALisrkealKENKSL 1504
Cdd:TIGR02169  691 SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK-------SELKEL 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1505 QEELSLARDTIEHLTKSLADVESHvsaqnkekdrvlgrlaLLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTED 1584
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALNDLEAR----------------LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1585 KEKLVKEIESLKSSKIaessEWQEKHKELQKEyeillqsyenvsneaeriqhvVEAVRQEKQELYGKLRSTEANKKETEK 1664
Cdd:TIGR02169  828 KEYLEKEIQELQEQRI----DLKEQIKSIEKE---------------------IENLNGKKEELEEELEELEAALRDLES 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1665 QLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLrAEVHPAGGTAKECMETLLSSNASMKEEVERVkMEYETLSKKF 1744
Cdd:TIGR02169  883 RLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL-SELKAKLEALEEELSEIEDPKGEDEEIPEEE-LSLEDVQAEL 960

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1622909128 1745 QSLMSEKDSLS-------EEVQDLKHQLESNVSKQANLEA 1777
Cdd:TIGR02169  961 QRVEEEIRALEpvnmlaiQEYEEVLKRLDELKEKRAKLEE 1000
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1294-2047 1.51e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.13  E-value: 1.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1294 SEDASALQGGTSVAQIKAQLKEIETEKEKL---ELKISSTTSELTKKSEEVFQLQDQINKQGLEIESL--KTASHEAEVR 1368
Cdd:pfam02463  216 KEKLELEEEYLLYLDYLKLNEERIDLLQELlrdEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLqeEELKLLAKEE 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1369 AESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQ 1448
Cdd:pfam02463  296 EELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEEL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1449 AKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESH 1528
Cdd:pfam02463  376 LAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEK 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1529 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQE 1608
Cdd:pfam02463  456 QELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLG 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1609 KHKELQKEYEILLQSYEN--VSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKS 1686
Cdd:pfam02463  536 VAVENYKVAISTAVIVEVsaTADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEA 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1687 KQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLE 1766
Cdd:pfam02463  616 DEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEIL 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1767 SNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQ 1846
Cdd:pfam02463  696 RRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKE 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1847 LKERIAGLEEEKQ--KNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDL 1924
Cdd:pfam02463  776 LAEEREKTEKLKVeeEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEE 855

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1925 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPG 2004
Cdd:pfam02463  856 LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE 935

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 1622909128 2005 NKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKAL 2047
Cdd:pfam02463  936 EPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLM 978
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1309-1920 1.85e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1309 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAEslqqklessqlqiagleh 1388
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKE------------------ 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1389 lrELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALhTQLEMQAKEHDERIKQLQVELCEMKQ 1468
Cdd:TIGR04523  170 --ELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQI-SELKKQNNQLKDNIEKKQQEINEKTT 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1469 KPEEIEEesrakqqiqrKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQ- 1547
Cdd:TIGR04523  247 EISNTQT----------QLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSEl 316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1548 EERDKLITEMDRSLLENQSLSGSceslklaLEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENV 1627
Cdd:TIGR04523  317 KNQEKKLEEIQNQISQNNKIISQ-------LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNL 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1628 SNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEvhp 1707
Cdd:TIGR04523  390 ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESL--- 466

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1708 aggtaKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNV 1787
Cdd:TIGR04523  467 -----ETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIS 541

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1788 TEEATQSIPGETEDQDSLSmstrpacsesvpsensanpavsedvsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1867
Cdd:TIGR04523  542 DLEDELNKDDFELKKENLE----------------------------KEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQ 593

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622909128 1868 LENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEE 1920
Cdd:TIGR04523  594 KEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQE 646
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1353-1991 1.85e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.67  E-value: 1.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1353 LEIESLktasheaEVRAESLQQKLESSQLQIAGLEHLRE-LQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEI 1431
Cdd:PRK01156   159 LEINSL-------ERNYDKLKDVIDMLRAEISNIDYLEEkLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAM 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1432 IEQEDLIKALH---------TQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENK 1502
Cdd:PRK01156   232 DDYNNLKSALNelssledmkNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKK 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1503 SLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRvlgrlallQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLT 1582
Cdd:PRK01156   312 QILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSR--------YDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYS 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1583 EDKEKLVKEIESLKSSKIAESSewqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELygklrstEANKKET 1662
Cdd:PRK01156   384 KNIERMSAFISEILKIQEIDPD-------AIKKELNEINVKLQDISSKVSSLNQRIRALRENLDEL-------SRNMEML 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1663 EKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNasmKEEVERVKMEYETLSK 1742
Cdd:PRK01156   450 NGQSVCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLE---SEEINKSINEYNKIES 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1743 KFQSLMSEKDSLSE-EVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSEN 1821
Cdd:PRK01156   527 ARADLEDIKIKINElKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEI 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1822 SANpavSEDVSSHDEinNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQ 1901
Cdd:PRK01156   607 EIG---FPDDKSYID--KSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIED 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1902 QIQEELSRVTKLKeTAEEEKDDLEERLMNQLAELNGSIGNycqdvtdaqiKNELLESeMKNLKKCVSELEEEKQQLvkEK 1981
Cdd:PRK01156   682 NLKKSRKALDDAK-ANRARLESTIEILRTRINELSDRIND----------INETLES-MKKIKKAIGDLKRLREAF--DK 747

                          650
                   ....*....|
gi 1622909128 1982 TKVESEIRKE 1991
Cdd:PRK01156   748 SGVPAMIRKS 757
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1572-2165 2.06e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 2.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1572 ESLKLALEGLTEDKEKLVKEIESLKsskiAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGK 1651
Cdd:COG1196    228 ELLLLKLRELEAELEELEAELEELE----AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQD 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1652 LRSTEANKKETEKQLQEAekemeemkekmrkfakskQQKILELEEENDRLRAEvhpaggtakecMETLLSSNASMKEEVE 1731
Cdd:COG1196    304 IARLEERRRELEERLEEL------------------EEELAELEEELEELEEE-----------LEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1732 RVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIpgETEDQDSLSMSTRP 1811
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER--LEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1812 ACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELK--LL 1889
Cdd:COG1196    433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvKA 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1890 QEEVSKMNLLNQQIQEELSRVtklketaEEEKDDLEERLMNQLAELNgsignycqdVTDAQIKNELLESEMKNLKKCVSE 1969
Cdd:COG1196    513 ALLLAGLRGLAGAVAVLIGVE-------AAYEAALEAALAAALQNIV---------VEDDEVAAAAIEYLKAAKAGRATF 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1970 LEEEKQQlvKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEF 2049
Cdd:COG1196    577 LPLDKIR--ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2050 VQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRL 2129
Cdd:COG1196    655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1622909128 2130 EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQ 2165
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1306-1774 2.11e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 2.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1306 VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAG 1385
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1386 LEHLRELQPELDELQKLISEKEEdvsylsgqLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAK----EHDERIKQLQV 1461
Cdd:COG4717    128 LPLYQELEALEAELAELPERLEE--------LEERLEELRELEEELEELEAELAELQEELEELLEqlslATEEELQDLAE 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1462 ELCEMKQKPEEIEEESRAKQQIQRKLQAA---LISRKEALKENKSLQEELSLAR----------------DTIEHLTKSL 1522
Cdd:COG4717    200 ELEELQQRLAELEEELEEAQEELEELEEEleqLENELEAAALEERLKEARLLLLiaaallallglggsllSLILTIAGVL 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1523 ADVESHVSAQNKEKDRvlgRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAE 1602
Cdd:COG4717    280 FLVLGLLALLFLLLAR---EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREA 356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1603 SSEWQE-KHKELQKEYEILLQSYeNVSNEAERIQHVVEAvrQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMR 1681
Cdd:COG4717    357 EELEEElQLEELEQEIAALLAEA-GVEDEEELRAALEQA--EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE 433

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1682 kfAKSKQQKILELEEENDRLRAEVhpagGTAKECMETLLSSN--ASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQ 1759
Cdd:COG4717    434 --LEELEEELEELEEELEELREEL----AELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLEEARE 507

                          490
                   ....*....|....*
gi 1622909128 1760 DLKHQLESNVSKQAN 1774
Cdd:COG4717    508 EYREERLPPVLERAS 522
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2584-2790 2.19e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 2.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2584 ANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEE 2663
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR--IAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2664 LVCVQKEAAKKVGEI-----EDKLK-----KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTA 2733
Cdd:COG4942     99 LEAQKEELAELLRALyrlgrQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 2734 QIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSE 2790
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1166-1395 2.70e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1166 EKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1245
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAEL----EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE- 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1246 IDGKLpspDQQEwcsptpGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTS------VAQIKAQLKEIETE 1319
Cdd:COG4942     95 LRAEL---EAQK------EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAparreqAEELRADLAELAAL 165

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128 1320 KEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPE 1395
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 318-1042 2.96e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 2.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  318 ESKILLEKMELEVAERKLSfhNLQEEMRHLLEQLEQAGQAQAELEsRYSAL-EQKHKAEMEEKTSHILSLQKTGQELQSA 396
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIE--RLDLIIDEKRQQLERLRREREKAE-RYQALlKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  397 CDALKDQnsklLQDKDEQAVQSAQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQTCFPDVYNEGTQAVTEENIASLQ 476
Cdd:TIGR02169  246 LASLEEE----LEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  477 KRVVELENEKGALLL----SSIELEELKAENEKLSSQITllEAQNRIGEADREVSEISIVDDANKRSSSTEESGQDVLEN 552
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAeieeLEREIEEERKRRDKLTEEYA--ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKR 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  553 TFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAE--EGDHEVLD-QKEMKQMEGEGIAPIKMevfLEDTGQNFPLMPN 629
Cdd:TIGR02169  400 EINELKRELDRLQEELQRLSEELADLNAAIAGIEAKinELEEEKEDkALEIKKQEWKLEQLAAD---LSKYEQELYDLKE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  630 E----ESSLPAVEKEQASTEHQNRTSEEISLNDAGVE--LKSTKQDCDKSLSAVPDIGQCHQDELE-----RLKSQILEL 698
Cdd:TIGR02169  477 EydrvEKELSKLQRELAEAEAQARASEERVRGGRAVEevLKASIQGVHGTVAQLGSVGERYATAIEvaagnRLNNVVVED 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  699 ELNFHKAQE---------------------------IYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQL 751
Cdd:TIGR02169  557 DAVAKEAIEllkrrkagratflplnkmrderrdlsiLSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLM 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  752 -----------------------LAQVKELSVVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLteqiHSLSIEAK 808
Cdd:TIGR02169  637 gkyrmvtlegelfeksgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRL----DELSQELS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  809 SKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKK 888
Cdd:TIGR02169  713 DASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  889 rdVETLQQTIEEKDQQVTEISFSMTEKMVQLNE---EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNY 965
Cdd:TIGR02169  793 --IPEIQAELSKLEEEVSRIEARLREIEQKLNRltlEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  966 DEMSPA--GLISK-EELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEED 1042
Cdd:TIGR02169  871 EELEAAlrDLESRlGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE 950
PTZ00121 PTZ00121
MAEBL; Provisional
 942-1612 3.89e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 3.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  942 RAEEAKKEQVEEDNEVVSGLK--QNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELA 1019
Cdd:PTZ00121  1183 KAEEVRKAEELRKAEDARKAEaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARM 1262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1020 NLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEE-QLQALVKE 1098
Cdd:PTZ00121  1263 AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAaKKKAEEAK 1342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1099 MNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNtDASDGDSVALVKETVVISPPGTDSGEHWKPELEE--KILALEKEKE 1176
Cdd:PTZ00121  1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE-AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElkKAAAAKKKAD 1421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1177 QLQKKLQEAltsRKAILKKAQEKERHLREELKQQKDDYNRLQEQfdEQSKENENIGDQLRQLQIQVRESIDGKLPSPDQQ 1256
Cdd:PTZ00121  1422 EAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEA--KKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK 1496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1257 EWCSPTPGLEEPLFKATEQHHTQPvlesnlcpdwpshsedasalqggtsvAQIKAQLKEIETEKEKLELKisstTSELTK 1336
Cdd:PTZ00121  1497 KKADEAKKAAEAKKKADEAKKAEE--------------------------AKKADEAKKAEEAKKADEAK----KAEEKK 1546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1337 KSEEVFQLQDQinKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQ 1416
Cdd:PTZ00121  1547 KADELKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE 1624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1417 LREKEAALTKI-QTEIIEQEDLIKAlhTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRK 1495
Cdd:PTZ00121  1625 LKKAEEEKKKVeQLKKKEAEEKKKA--EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1496 EALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVlgrLALLQEERDKLITEMDRSLLENQSLSGSCESLK 1575
Cdd:PTZ00121  1703 KAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA---EEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA 1779

                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 1622909128 1576 LALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKE 1612
Cdd:PTZ00121  1780 VIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1297-1705 5.20e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 5.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1297 ASALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLE-IESLKTASHEAEVRAESLQQK 1375
Cdd:COG4913    281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDrLEQLEREIERLERELEERERR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1376 LESSQLQIAGLEH-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE 1454
Cdd:COG4913    361 RARLEALLAALGLpLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPA 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1455 RIKQLQVELCE---------------MKQKPEE------IE-------------------------------------EE 1476
Cdd:COG4913    441 RLLALRDALAEalgldeaelpfvgelIEVRPEEerwrgaIErvlggfaltllvppehyaaalrwvnrlhlrgrlvyerVR 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1477 SRAKQQIQRKLQAALISRKEALKENKS---LQEELSLARD-----------------TIEHLTKSLADVESHVSAQNKEK 1536
Cdd:COG4913    521 TGLPDPERPRLDPDSLAGKLDFKPHPFrawLEAELGRRFDyvcvdspeelrrhpraiTRAGQVKGNGTRHEKDDRRRIRS 600

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1537 DRVLG-----RLALLQEERDKL---ITEMDRSLLENQSLSGSCESLKLALEGLTE------DKEKLVKEIESLKS--SKI 1600
Cdd:COG4913    601 RYVLGfdnraKLAALEAELAELeeeLAEAEERLEALEAELDALQERREALQRLAEyswdeiDVASAEREIAELEAelERL 680

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1601 AESSEW----QEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEM 1676
Cdd:COG4913    681 DASSDDlaalEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG 760

                          490       500
                   ....*....|....*....|....*....
gi 1622909128 1677 KEKMRKFAKSKQQKILELEEENDRLRAEV 1705
Cdd:COG4913    761 DAVERELRENLEERIDALRARLNRAEEEL 789
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2219-2983 7.15e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.89  E-value: 7.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2219 DAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEET 2298
Cdd:TIGR00606  224 DQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2299 RHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEgiIRQQEADIQNSKFSYEQLETDLQAsreLTSRLHEE 2378
Cdd:TIGR00606  304 NDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELL--VEQGRLQLQADRHQEHIRARDSLI---QSLATRLE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2379 INMKEQKMISllsgkEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQK 2458
Cdd:TIGR00606  379 LDGFERGPFS-----ERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2459 AQLDSFVKSMSSLQNDRDRIVGDYQQL--EERHLSvILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE-- 2534
Cdd:TIGR00606  454 EELKFVIKELQQLEGSSDRILELDQELrkAERELS-KAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtt 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2535 -------LIQYREDLNQVISIKDSQQKQLLEAQL---QQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSK 2604
Cdd:TIGR00606  533 trtqmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINN 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2605 EIESLKVSVSQLTRQV----TALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKeAAKKVGEIED 2680
Cdd:TIGR00606  613 ELESKEEQLSSYEDKLfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCP-VCQRVFQTEA 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2681 KLKKELKHLHHDAGIMRNETETAEERVAELARD------LVEMEQKLL-MVTKENKDLTAQIQSFGRSMSSLQNSRDHAN 2753
Cdd:TIGR00606  692 ELQEFISDLQSKLRLAPDKLKSTESELKKKEKRrdemlgLAPGRQSIIdLKEKEIPELRNKLQKVNRDIQRLKNDIEEQE 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2754 EELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQ 2833
Cdd:TIGR00606  772 TLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKL 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2834 VQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ-INQ 2912
Cdd:TIGR00606  852 IQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEElISS 931

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909128 2913 EITELRPLKAQLQEYQDKTKT--------FQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQ 2983
Cdd:TIGR00606  932 KETSNKKAQDKVNDIKEKVKNihgymkdiENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ 1010
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1831-2046 8.26e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 8.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1831 VSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEvskMNLLNQQIQEELSRV 1910
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE---LAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1911 TKLKETAEEEKDDLEERL------------------------------MNQLAE-LNGSIGNYCQDVTDAQIKNELLESE 1959
Cdd:COG4942     93 AELRAELEAQKEELAELLralyrlgrqpplalllspedfldavrrlqyLKYLAPaRREQAEELRADLAELAALRAELEAE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1960 MKNLKKCVSELEEEKQQLVKEKTKVESEIrkeylekiqgaqkepgnkshaKELQELLKEKQQEVKQLQKDCIRYQEKISA 2039
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLL---------------------ARLEKELAELAAELAELQQEAEELEALIAR 231


                   ....*..
gi 1622909128 2040 LERTVKA 2046
Cdd:COG4942    232 LEAEAAA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2680-2906 9.49e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 9.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2680 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDEL 2759
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2760 KRKYDASLKELAQLKEQQGLLnrerhALLSETTFSMDLpeeNSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSK 2839
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLA-----LLLSPEDFLDAV---RRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 2840 AMASLQNERDHLWNELEKFRKSEEGKQRSAAQpatslaEVQSLKKAMSSLQNDRDRLLKELKNLQQQ 2906
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIARLEAE 235
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2010-2191 9.83e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 9.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2010 KELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELA--------- 2080
Cdd:COG4942     37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAellralyrl 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2081 ----SFKVLLD-DTQSEAARVLADNLKLKKELQSNKESVKSQmKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKV 2155
Cdd:COG4942    117 grqpPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRAD-LAELAALRAELEAERAELEALLAELEEERAALEALKA 195

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1622909128 2156 HLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAA 2191
Cdd:COG4942    196 ERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2445-2663 1.13e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2445 ETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsvILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2524
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR----IAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2525 NSENAKLDAELIQY---------REDLNQVISIKDSQQ--------KQLLEAQLQQNKELKNKYAKLEEKLKESEEANED 2587
Cdd:COG4942     96 RAELEAQKEELAELlralyrlgrQPPLALLLSPEDFLDavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128 2588 LQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQeegtlgiyhAQLKVKEEELQRLSALLSSSQKRITELEEE 2663
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELA---------AELAELQQEAEELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
702-1216 1.13e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 1.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  702 FHKAQeiyeknldeKAKEISNLNQLIEEF-------KKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEmn 774
Cdd:COG4913    197 LHKTQ---------SFKPIGDLDDFVREYmleepdtFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYA-- 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  775 lAEAERQRRFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAE 854
Cdd:COG4913    266 -AARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  855 R--------VRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSL 926
Cdd:COG4913    345 ReierlereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELREL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  927 GVEIKTLKE-QLNLLSRAEEAKKE-------------------QVEEDNE------------------------------ 956
Cdd:COG4913    425 EAEIASLERrKSNIPARLLALRDAlaealgldeaelpfvgeliEVRPEEErwrgaiervlggfaltllvppehyaaalrw 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  957 -------------VVSGLKQNYDEMS--PAGLISK-------------EELQHEFDLLKKENEQRKRKLQAAL------- 1001
Cdd:COG4913    505 vnrlhlrgrlvyeRVRTGLPDPERPRldPDSLAGKldfkphpfrawleAELGRRFDYVCVDSPEELRRHPRAItragqvk 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1002 -------------INRKELL-----QRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEI- 1062
Cdd:COG4913    585 gngtrhekddrrrIRSRYVLgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVa 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1063 SLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQT---LQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDS 1139
Cdd:COG4913    665 SAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELeeeLDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR 744

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 1140 VALVketvvisppgtdsgehwkPELEEKILALEKEKeqLQKKLQEALTSRkaiLKKAQEKERHLREELKQQKDDYNR 1216
Cdd:COG4913    745 LELR------------------ALLEERFAAALGDA--VERELRENLEER---IDALRARLNRAEEELERAMRAFNR 798
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2698-2926 1.21e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2698 NETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQ 2777
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2778 gllnRERHALLSETtfsmdlpeensLSYLEKLNQQllsKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEK 2857
Cdd:COG4942    100 ----EAQKEELAEL-----------LRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE 161

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622909128 2858 FRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKEL----KNLQQQYLQINQEITELRPLKAQLQE 2926
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLekelAELAAELAELQQEAEELEALIARLEA 234
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 710-907 1.23e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  710 EKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKelsvvtELRAQVRQLEMNLAEAERQRRFDYESQ 789
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR------ALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  790 TAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQA 869
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1622909128  870 LSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTE 907
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 829-1125 1.31e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.61  E-value: 1.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  829 SEQSTLIRSLQSQ--LQNKESEVLEGAERVRHISSKVEELSQALS--QKELEIAKMDQLLLE--KKRDVETLQQTIEEKD 902
Cdd:PRK05771    16 SYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDklRSYLPKLNPLREEKKkvSVKSLEELIKDVEEEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  903 QQVTEISFSMTEKMVQLNEEKFSLGVEIKTLK--EQLNLlsraeEAKKEQveeDNEVVSGLkqnydemspAGLISKEELQ 980
Cdd:PRK05771    96 EKIEKEIKELEEEISELENEIKELEQEIERLEpwGNFDL-----DLSLLL---GFKYVSVF---------VGTVPEDKLE 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  981 HEFDLLKKENE----QRKRKLQAALINRKELLQRVsrlEEELANLkDQSKKEIPlsesERGEVEEdkenkEYSEkcvtsk 1056
Cdd:PRK05771   159 ELKLESDVENVeyisTDKGYVYVVVVVLKELSDEV---EEELKKL-GFERLELE----EEGTPSE-----LIRE------ 219

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909128 1057 cqeieisLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQidLLQAEISENQVIIQ 1125
Cdd:PRK05771   220 -------IKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELERAEA--LSKFLKTDKTFAIE 279
46 PHA02562
endonuclease subunit; Provisional
 1835-1995 1.39e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.70  E-value: 1.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1835 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKL-------------LQEEVSKMNLLNQ 1901
Cdd:PHA02562   227 EEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMyekggvcptctqqISEGPDRITKIKD 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1902 QIQEELSRVTKLKETAEEEKDDLEERLMNQ--LAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVK 1979
Cdd:PHA02562   307 KLKELQHSLEKLDTAIDELEEIMDEFNEQSkkLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386

                          170
                   ....*....|....*.
gi 1622909128 1980 EKTKVESEIRKEYLEK 1995
Cdd:PHA02562   387 ELDKIVKTKSELVKEK 402
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1578-1990 1.42e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1578 LEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEillqSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1657
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEE----EYAELQEELEELEEELEELEAELEELREELEKLEK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1658 NKKETEKQLQEAEKEMEEMKEKMR-KFAKSKQQKILELEEENDRLRAEVHPAggtAKECMETLLSSNASMKEEVERVKME 1736
Cdd:COG4717    124 LLQLLPLYQELEALEAELAELPERlEELEERLEELRELEEELEELEAELAEL---QEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1737 YETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPA---- 1812
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAgvlf 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1813 --------CSESVPSENSANPAVSEDVSSHDEINNYLQQI--DQLKERIAGLEEEKQKNKEFSQTLEnERNALLSQISTK 1882
Cdd:COG4717    281 lvlgllalLFLLLAREKASLGKEAEELQALPALEELEEEEleELLAALGLPPDLSPEELLELLDRIE-ELQELLREAEEL 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1883 DGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER--LMNQLAELNGSIGNYCQDVTDAQIKNELLESEM 1960
Cdd:COG4717    360 EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELeeLEEQLEELLGELEELLEALDEEELEEELEELEE 439

                          410       420       430
                   ....*....|....*....|....*....|
gi 1622909128 1961 KnlkkcVSELEEEKQQLVKEKTKVESEIRK 1990
Cdd:COG4717    440 E-----LEELEEELEELREELAELEAELEQ 464
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1391-2323 1.47e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.86  E-value: 1.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1391 ELQPELDELQKlISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKP 1470
Cdd:pfam01576    6 EMQAKEEELQK-VKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1471 EEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLAD----VESHVSAQNKEKDRVLGRLAll 1546
Cdd:pfam01576   85 EEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEdillLEDQNSKLSKERKLLEERIS-- 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1547 qeERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYEN 1626
Cdd:pfam01576  163 --EFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAK 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1627 VSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEEND------R 1700
Cdd:pfam01576  241 KEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDttaaqqE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1701 LRAEVHPAGGTAKECMETLLSSN---------------ASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQL 1765
Cdd:pfam01576  321 LRSKREQEVTELKKALEEETRSHeaqlqemrqkhtqalEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAK 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1766 ESNVSKQANLEA-----TEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNY 1840
Cdd:pfam01576  401 QDSEHKRKKLEGqlqelQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEE 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1841 LQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETA--- 1917
Cdd:pfam01576  481 TRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALtqq 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1918 EEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQ 1997
Cdd:pfam01576  561 LEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALS 640

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1998 GAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQA 2077
Cdd:pfam01576  641 LARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV 720

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2078 ELASFKVLLD------DTQSE--------AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQA---EEKHLKEK 2140
Cdd:pfam01576  721 NMQALKAQFErdlqarDEQGEekrrqlvkQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAAnkgREEAVKQL 800

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2141 KNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKW------- 2213
Cdd:pfam01576  801 KKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGasgksal 880

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2214 ---ERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQtevqlqqkvcdTLQGENKE 2290
Cdd:pfam01576  881 qdeKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQ-----------QLERQNKE 949

                          970       980       990
                   ....*....|....*....|....*....|....
gi 1622909128 2291 LLSQLEETRHLYHNSQ-NELAKLESELNILKDQL 2323
Cdd:pfam01576  950 LKAKLQEMEGTVKSKFkSSIAALEAKIAQLEEQL 983
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 194-958 1.49e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.76  E-value: 1.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  194 QLQEKEELISTLQAQLSQTQAEQAaQVVREKDARFETQVRLhEDELLQLVTQADVETEMQQklRVLQRKLEEHEESLVGR 273
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELE-KLTEEISELEKRLEEI-EQLLEELNKKIKDLGEEEQ--LRVKEKIGELEAEIASL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  274 AQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQE----------- 342
Cdd:TIGR02169  307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEvdkefaetrde 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  343 --------------------EMRHLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKD 402
Cdd:TIGR02169  387 lkdyrekleklkreinelkrELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  403 QNSKLLQDKdeqavqsaQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQTCFPDVYNEGTQAV---TEENIASLQKRV 479
Cdd:TIGR02169  467 YEQELYDLK--------EEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  480 VELENEKGALLLSSIELEELKAE------NEKLSSQITLLEAqNRIGEADREVSEISivddankrssstEESGQDVLEN- 552
Cdd:TIGR02169  539 TAIEVAAGNRLNNVVVEDDAVAKeaiellKRRKAGRATFLPL-NKMRDERRDLSILS------------EDGVIGFAVDl 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  553 -TFSQKHKELSVLLLEMKEAQEEIaflklqlqgkraeEGDHEVLDQKEMKQMEGEGIAP---IKMEVFLEDTGQNFPLMP 628
Cdd:TIGR02169  606 vEFDPKYEPAFKYVFGDTLVVEDI-------------EAARRLMGKYRMVTLEGELFEKsgaMTGGSRAPRGGILFSRSE 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  629 NEESSLPAVEKEQASTEHQNRTSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEI 708
Cdd:TIGR02169  673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  709 YEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKElsvvtELRAQVRQLEMNLAEAERQRrfdyes 788
Cdd:TIGR02169  753 IENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS-----KLEEEVSRIEARLREIEQKL------ 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  789 qtahhNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQ 868
Cdd:TIGR02169  822 -----NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  869 ALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEkMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK 948
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE-DEEIPEEELSLEDVQAELQRVEEEIRALEPVNM 975

                          810
                   ....*....|
gi 1622909128  949 EQVEEDNEVV 958
Cdd:TIGR02169  976 LAIQEYEEVL 985
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2302-2907 1.53e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 1.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2302 YHNSQNELAKLESELNILKDqltdlsnSLEKCKEQKENLEGIIRQQEAdiqnskfsyeqletdlqasrELTSRLHEeinm 2381
Cdd:PRK03918   160 YENAYKNLGEVIKEIKRRIE-------RLEKFIKRTENIEELIKEKEK--------------------ELEEVLRE---- 208

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2382 keqkmISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKEniqqKAQL 2461
Cdd:PRK03918   209 -----INEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKE----IEEL 278

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2462 DSFVKSMSSLQNDRDRivgdYQQLEERHLSVILEKDQLIQEAAaennKLKEEIRGLRSHMDDLNSENAKLDAELIQYRED 2541
Cdd:PRK03918   279 EEKVKELKELKEKAEE----YIKLSEFYEEYLDELREIEKRLS----RLEEEINGIEERIKELEEKEERLEELKKKLKEL 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2542 LNQVISIKDSQQK-QLLEAQLQQNKELKNKYAKL-----EEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQ 2615
Cdd:PRK03918   351 EKRLEELEERHELyEEAKAKKEELERLKKRLTGLtpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2616 LT----------RQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEEL-----VCVQKEAAKKVGEIED 2680
Cdd:PRK03918   431 LKkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLkkeseLIKLKELAEQLKELEE 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2681 KLKK-----------ELKHLHHDAGIMRNETETAE---ERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSmsslq 2746
Cdd:PRK03918   511 KLKKynleelekkaeEYEKLKEKLIKLKGEIKSLKkelEKLEELKKKLAELEKKLDELEEELAELLKELEELGFE----- 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2747 nSRDHANEELDELKRKYDASLKELAQLKEQQGLLNR-ERHALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHlss 2825
Cdd:PRK03918   586 -SVEELEERLKELEPFYNEYLELKDAEKELEREEKElKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY--- 661

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2826 qlEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRlLKELKNLQQ 2905
Cdd:PRK03918   662 --EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREK-VKKYKALLK 738


                   ..
gi 1622909128 2906 QY 2907
Cdd:PRK03918   739 ER 740
PTZ00121 PTZ00121
MAEBL; Provisional
 861-1245 1.59e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.83  E-value: 1.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  861 SKVEELSQALSQKELEIAKMDQlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlneekfslgvEIKTLKEQLNLL 940
Cdd:PTZ00121  1366 AEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAKK------------KADEAKKKAEEK 1430

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  941 SRAEEAKKeQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAalinrKELLQRVSRLEEELAN 1020
Cdd:PTZ00121  1431 KKADEAKK-KAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA-----KKKAEEAKKKADEAKK 1504

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1021 LKDQSKKEIPLSESERG-EVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEM 1099
Cdd:PTZ00121  1505 AAEAKKKADEAKKAEEAkKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAE 1584

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1100 NQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKEtvvisppgtdsgEHWKPELEEKILALEKEKEQLQ 1179
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE------------EKKKVEQLKKKEAEEKKKAEEL 1652

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128 1180 KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1245
Cdd:PTZ00121  1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA 1718
PTZ00121 PTZ00121
MAEBL; Provisional
 704-1244 1.69e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.83  E-value: 1.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  704 KAQEIYEKNLDEKAKEISNLNQLIEEFKK----NADNNSSAFTALSEERDQLLAQVKELSVVTELRA--QVRQLEMNLAE 777
Cdd:PTZ00121  1231 KAEEAKKDAEEAKKAEEERNNEEIRKFEEarmaHFARRQAAIKAEEARKADELKKAEEKKKADEAKKaeEKKKADEAKKK 1310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  778 AERQRRFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEG-AERV 856
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKkAEEK 1390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  857 R---HISSKVEEL---SQALSQKELEIAKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGV 928
Cdd:PTZ00121  1391 KkadEAKKKAEEDkkkADELKKAAAAKKKADEAKkkAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  929 EIKTLKEQLNLLSRAEEAKKeQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKrklqAALINRKELL 1008
Cdd:PTZ00121  1471 KADEAKKKAEEAKKADEAKK-KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK----ADEAKKAEEK 1545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1009 QRVSRLEEELANLKDQSKKEIplsESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAA 1088
Cdd:PTZ00121  1546 KKADELKKAEELKKAEEKKKA---EEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1089 E-----EQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvispPGTDSGEHWKPE 1163
Cdd:PTZ00121  1623 EelkkaEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE-----DEKKAAEALKKE 1697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1164 LEEKilaleKEKEQLQKKLQEALTSRKAiLKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVR 1243
Cdd:PTZ00121  1698 AEEA-----KKAEELKKKEAEEKKKAEE-LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771


                   .
gi 1622909128 1244 E 1244
Cdd:PTZ00121  1772 E 1772
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1846-2177 1.75e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.43  E-value: 1.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1846 QLKERIAGLEEEKQKNKEFSQTLENERNALLSQIST-KDGELKLLQEEVSKMNLLNQQIQEELSRVTKlketaEEEKDDL 1924
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKaRQAEMDRQAAIYAEQERMAMERERELERIRQ-----EERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1925 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepg 2004
Cdd:pfam17380  363 ERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARK-VKILEEERQRKIQQQKVEMEQIRAEQEEARQ------- 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2005 nkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALErtvkalefvqtesQKDLEITKENLAQAVEHRKKAQAELASFKV 2084
Cdd:pfam17380  435 -----REVRRLEEERAREMERVRLEEQERQQQVERLR-------------QQEEERKRKKLELEKEKRDRKRAEEQRRKI 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2085 LLDDTQSEAARVLADNLK---LKKELQSNKESVKSQMKQKDEDLERRleqaEEKHLKEKKNMQEKLDALRREKVHLEETI 2161
Cdd:pfam17380  497 LEKELEERKQAMIEEERKrklLEKEMEERQKAIYEEERRREAEEERR----KQQEMEERRRIQEQMRKATEERSRLEAME 572

                          330
                   ....*....|....*.
gi 1622909128 2162 GEIQVTLNKKDKEIQQ 2177
Cdd:pfam17380  573 REREMMRQIVESEKAR 588
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1080-1521 1.83e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1080 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPPGTDsgeh 1159
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLE---- 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1160 wkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1239
Cdd:COG4717    150 ---ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1240 IQVRESIDGKLPSPDQQ--EWCSPTPGLEEPLFKATEQHHTQPVLESNLCP----------------DWPSHSEDASALQ 1301
Cdd:COG4717    227 EELEQLENELEAAALEErlKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlflvlgllallflllAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1302 GGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESsql 1381
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVED--- 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1382 qiagLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEdlikalHTQLEMQAKEHDERIKQLQV 1461
Cdd:COG4717    384 ----EEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE------LEELEEELEELEEELEELRE 453

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1462 ELCEMKQKPEEIEEESRAkQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKS 1521
Cdd:COG4717    454 ELAELEAELEQLEEDGEL-AELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
mukB PRK04863
chromosome partition protein MukB;
2697-3020 1.94e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 1.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2697 RNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDH------------------------- 2751
Cdd:PRK04863   292 RRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQqekieryqadleeleerleeqnevv 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2752 --ANEELDELKRKYDASLKELAQLKEQ-----QGLLNRERHAL-----------LSETTFSMDLPEENSLSYLEKLNQQL 2813
Cdd:PRK04863   372 eeADEQQEENEARAEAAEEEVDELKSQladyqQALDVQQTRAIqyqqavqalerAKQLCGLPDLTADNAEDWLEEFQAKE 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2814 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQN-----ERDHLWNE-LEKFRKSEEgkQRSAAQPATSL-AEVQSLKKAM 2886
Cdd:PRK04863   452 QEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKiagevSRSEAWDVaRELLRRLRE--QRHLAEQLQQLrMRLSELEQRL 529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2887 sSLQNDRDRLLKELKNLQQQYLQINQEITELR-PLKAQLQEYQDKTKTFQIMQEELRQENLSWQHELHQLRMEKSSW-EI 2964
Cdd:PRK04863   530 -RQQQRAERLLAEFCKRLGKNLDDEDELEQLQeELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWlAA 608

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909128 2965 HER--RMKEQYLMAISDKDQQVSHLQNLIRELRS-------SSSQAQPLKVQYQRQASPETSASP 3020
Cdd:PRK04863   609 QDAlaRLREQSGEEFEDSQDVTEYMQQLLEREREltverdeLAARKQALDEEIERLSQPGGSEDP 673
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2109-2787 2.43e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.14  E-value: 2.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2109 SNKESVKSQMKQKDEDLERRLEqaEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQ 2188
Cdd:pfam12128  207 EDDGVVPPKSRLNRQQVEHWIR--DIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQET 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2189 LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEEncsvlkDQLRQMSIHMEELKINISRLEhdkqiwes 2268
Cdd:pfam12128  285 SAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALED------QHGAFLDADIETAAADQEQLP-------- 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2269 KAQTEVQLQQKVCDTLQGENKELlSQLEETRHLYHNSQN--ELAKLESELNILKDQLTDLsnsLEKCKEQKENLEGIIRQ 2346
Cdd:pfam12128  351 SWQSELENLEERLKALTGKHQDV-TAKYNRRRSKIKEQNnrDIAGIKDKLAKIREARDRQ---LAVAEDDLQALESELRE 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2347 QeADIQNSKFSYEQLETDLQASrELTSRLHEEINMKEQKMisllsgKEEAIQVAIAELRQQHDKEIKELENLLSQEEEEN 2426
Cdd:pfam12128  427 Q-LEAGKLEFNEEEYRLKSRLG-ELKLRLNQATATPELLL------QLENFDERIERAREEQEAANAEVERLQSELRQAR 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2427 IVLEEENKKAVDKTNQLMETLNAIkkeniqQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAE 2506
Cdd:pfam12128  499 KRRDQASEALRQASRRLEERQSAL------DELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2507 NNKLKEEIRGLRSHMDDLN-SENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEAN 2585
Cdd:pfam12128  573 SVGGELNLYGVKLDLKRIDvPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNAR 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2586 EDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKE-------EELQRLSALLSSSQKRIT 2658
Cdd:pfam12128  653 LDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEqkreartEKQAYWQVVEGALDAQLA 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2659 ELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDagimrnetetaEERVAELARDLVEMEQKLLMVTKENKDLTaQIQSF 2738
Cdd:pfam12128  733 LLKAAIAARRSGAKAELKALETWYKRDLASLGVD-----------PDVIAKLKREIRTLERKIERIAVRRQEVL-RYFDW 800

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622909128 2739 GRSMSSLQnsRDHANEELDELKRKYDASLKELAQLKEQQGL----LNRERHAL 2787
Cdd:pfam12128  801 YQETWLQR--RPRLATQLSNIERAISELQQQLARLIADTKLrrakLEMERKAS 851
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 711-1248 2.66e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.94  E-value: 2.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  711 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELsvvtelRAQVRQLEMNLAEAERQRRFDYESQT 790
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDL------KKQKEELENELNLLEKEKLNIQKNID 190

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  791 AHHNLLTEQIHSLSIeAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQAL 870
Cdd:TIGR04523  191 KIKNKLLKLELLLSN-LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  871 SQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKF---------------SLGVEIKTLKE 935
Cdd:TIGR04523  270 SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLeeiqnqisqnnkiisQLNEQISQLKK 349

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  936 QLNLLSRAEEAKKEQVEEDNEVVSGLK---QNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS 1012
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKkenQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1013 RLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEiSLKQTISEKEVELEHIRKDLEEKMAAEEQL 1092
Cdd:TIGR04523  430 RLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSIN-KIKQNLEQKQKELKSKEKELKKLNEEKKEL 508

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1093 QALVKEMNQTLQDKTNQIDLLQAEISE-NQVIIQKLTTSNTDASDGDSVALVKEtvvisppgTDSGEHWKPELEEKILAL 1171
Cdd:TIGR04523  509 EEKVKDLTKKISSLKEKIEKLESEKKEkESKISDLEDELNKDDFELKKENLEKE--------IDEKNKEIEELKQTQKSL 580

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 1172 EKEKEQLQKKLQEALTSRKAILKKAQEKERhLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1248
Cdd:TIGR04523  581 KKKQEEKQELIDQKEKEKKDLIKEIEEKEK-KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1942-2626 2.96e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.65  E-value: 2.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1942 YCQDVTDAQIK----NELLESEMKNLKKCVSELEEEKQQLVKEKTKVeSEIRKEYLEKIQGAQKEPGNKSH----AKELQ 2013
Cdd:pfam15921   83 YSHQVKDLQRRlnesNELHEKQKFYLRQSVIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHeleaAKCLK 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2014 E-LLKEKQQEVKQLQKDCIRYQEKISALERTVkaLEFVQTESQKdleITKENLAQAVEHRKKAQAelasFKVLLDDTQSE 2092
Cdd:pfam15921  162 EdMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL--VDFEEASGKK---IYEHDSMSTMHFRSLGSA----ISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2093 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2172
Cdd:pfam15921  233 ISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQN 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2173 KEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDeaKKWERKFSDAIQTKEEEIRLKEENCSvLKDQLRQM--SIHME 2250
Cdd:pfam15921  313 SMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELE--KQLVLANSELTEARTERDQFSQESGN-LDDQLQKLlaDLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2251 ELKINISRlEHDKQIWESKAQTEVQLQ-------------QKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESeln 2317
Cdd:pfam15921  390 EKELSLEK-EQNKRLWDRDTGNSITIDhlrrelddrnmevQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSS--- 465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2318 iLKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKE--- 2394
Cdd:pfam15921  466 -LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDhlr 544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2395 ------EAIQVAIAE-------LRQQhdkeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQL 2461
Cdd:pfam15921  545 nvqtecEALKLQMAEkdkvieiLRQQ----IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKI 620

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2462 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQE---AAAENNKLKEEI----RGLRSHMDDLNSENAKLDAE 2534
Cdd:pfam15921  621 RELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTTNKLKMQ 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2535 LIQYREDLNQV------ISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIES 2608
Cdd:pfam15921  701 LKSAQSELEQTrntlksMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELST 780

                          730
                   ....*....|....*...
gi 1622909128 2609 LKVSVSQLTRQVTALQEE 2626
Cdd:pfam15921  781 VATEKNKMAGELEVLRSQ 798
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 1901-2462 3.05e-04

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 46.75  E-value: 3.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1901 QQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSElEEEKQQLVKE 1980
Cdd:PTZ00440   479 EKDSMDSKEKKESSDSNYQEKVDELLQIINSIKEKNNIVNNNFKNIEDYYITIEGLKNEIEGLIELIKY-YLQSIETLIK 557

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1981 KTKVESEIRKEYLEKIQGAQkepGNKSHAKELQELLKEKQ---QEVKQLQKDCIRYQEKISALERTVKAL--EFVQTESQ 2055
Cdd:PTZ00440   558 DEKLKRSMKNDIKNKIKYIE---ENVDHIKDIISLNDEIDniiQQIEELINEALFNKEKFINEKNDLQEKvkYILNKFYK 634

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2056 KDLEITKENLAQAVEHRKKAQAELAS---FKVLLDDTQSEAARVL---ADNL-----KLKKELQSNKESVKSQMKQKDED 2124
Cdd:PTZ00440   635 GDLQELLDELSHFLDDHKYLYHEAKSkedLQTLLNTSKNEYEKLEfmkSDNIdniikNLKKELQNLLSLKENIIKKQLNN 714

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2125 LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLE---ETIGEIQ----VTLNKKDKEI-------QQVQENLDSTVAQLA 2190
Cdd:PTZ00440   715 IEQDISNSLNQYTIKYNDLKSSIEEYKEEEEKLEvykHQIINRKnefiLHLYENDKDLpdgkntyEEFLQYKDTILNKEN 794

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2191 AFTKSMSSLQDDRDRVIDEAKKWE-----------------RKFSDAIQTKEEEIRLKE------ENCSVLKDQLRQMSI 2247
Cdd:PTZ00440   795 KISNDINILKENKKNNQDLLNSYNiliqkleahtekndeelKQLLQKFPTEDENLNLKElekefnENNQIVDNIIKDIEN 874

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2248 H------MEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESEL-NILK 2320
Cdd:PTZ00440   875 MnkniniIKTLNIAINRSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDNIIQKNEKLNLLNNLNKEKEKIEKQLsDTKI 954

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2321 DQL-TDLSNSLEKCKEQKENLEGI-------IRQQEADIQNSKFSYEQLETDLQAsreLTSRLHEEINMKEQKMISLLSG 2392
Cdd:PTZ00440   955 NNLkMQIEKTLEYYDKSKENINGNdgthlekLDKEKDEWEHFKSEIDKLNVNYNI---LNKKIDDLIKKQHDDIIELIDK 1031

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2393 KEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLD 2462
Cdd:PTZ00440  1032 LIKEKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEALLKKIDENKNKLI 1101
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2678-2936 3.11e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.46  E-value: 3.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2678 IEDKLKKELKHLHhDAGIMRNE---TETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGR-SMSSLQNSRDHAN 2753
Cdd:PRK05771    14 LKSYKDEVLEALH-ELGVVHIEdlkEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKvSVKSLEELIKDVE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2754 EELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYL---------EKLNQQLLSKDEQLLHLS 2824
Cdd:PRK05771    93 EELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGNFDLDLSLLLGFKYVsvfvgtvpeDKLEELKLESDVENVEYI 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2825 SQLEDSYNQVQSFSKAMASLQNE--RDHlwnELEKFRKSEEGkqrsaaqpaTSLAEVQSLKKAMSSLQNDRDRLLKELKN 2902
Cdd:PRK05771   173 STDKGYVYVVVVVLKELSDEVEEelKKL---GFERLELEEEG---------TPSELIREIKEELEEIEKERESLLEELKE 240

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1622909128 2903 LQQQYLQINQEITELRPLKAQLQEYQDKT----KTFQI 2936
Cdd:PRK05771   241 LAKKYLEELLALYEYLEIELERAEALSKFlktdKTFAI 278
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 795-1026 3.28e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  795 LLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE 874
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  875 LEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEI----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAE 944
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  945 EAKKEQVEEDNEVVSGLKQNYDEMspaglisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQ 1024
Cdd:COG4942    170 EAERAELEALLAELEEERAALEAL-------KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242


                   ..
gi 1622909128 1025 SK 1026
Cdd:COG4942    243 TP 244
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1768-2174 3.46e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.43  E-value: 3.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1768 NVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPAC-SESVPSENSANPAVSEDVSSHDEINNYLQQIDQ 1846
Cdd:PLN02939    41 GFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELpQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1847 LKERIAGLEEEkqknkEFSQTLEN-ERNALLsqistkdgelkllqeevskMNLLNQQIQEELSRVTKLKETAEEEKDDLE 1925
Cdd:PLN02939   121 DGEQLSDFQLE-----DLVGMIQNaEKNILL-------------------LNQARLQALEDLEKILTEKEALQGKINILE 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1926 ERLMNQLAELNGSignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEkiqgaqkepgn 2005
Cdd:PLN02939   177 MRLSETDARIKLA--------AQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENML----------- 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2006 kshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDL----EITKENLAQAVEhrkkaqaelaS 2081
Cdd:PLN02939   238 ---LKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVsklsPLQYDCWWEKVE----------N 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2082 FKVLLDDTQSE---AARVLADNLKLKKELQSNKESVKSQMKQKD-----EDLERRLEQAEEKHLKEKKNMQEKLDAlrre 2153
Cdd:PLN02939   305 LQDLLDRATNQvekAALVLDQNQDLRDKVDKLEASLKEANVSKFssykvELLQQKLKLLEERLQASDHEIHSYIQL---- 380

                          410       420
                   ....*....|....*....|.
gi 1622909128 2154 kvhLEETIGEIQVTLNKKDKE 2174
Cdd:PLN02939   381 ---YQESIKEFQDTLSKLKEE 398
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 662-1238 3.95e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 46.58  E-value: 3.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  662 ELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAqeIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAF 741
Cdd:TIGR01612 1119 DIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLL 1196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  742 TALSE-ERDQL-LAQVKELSVVTELRAQVRQLEmNLAEAERQRRFDYESQTAHHNLLTE------QIHSLSIEAKSKDVK 813
Cdd:TIGR01612 1197 NEIAEiEKDKTsLEEVKGINLSYGKNLGKLFLE-KIDEEKKKSEHMIKAMEAYIEDLDEikekspEIENEMGIEMDIKAE 1275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  814 IEVLQNELDDVQLQFSEQSTLIRSLqSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVET 893
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNI 1354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  894 LQ-QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLlsraeEAKKEQVEE--DNEVVSGLKQNYDEMSP 970
Cdd:TIGR01612 1355 LKlNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINL-----EECKSKIEStlDDKDIDECIKKIKELKN 1429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  971 AGLISKEELQHEFDLLKKENEQrkrklqaALINRKELLQRVSRLEEELANLKDQSKKEIPLSesergeVEEDKENKEYSE 1050
Cdd:TIGR01612 1430 HILSEESNIDTYFKNADENNEN-------VLLLFKNIEMADNKSQHILKIKKDNATNDHDFN------INELKEHIDKSK 1496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1051 KCVTskcqEIEISLKQTISEKEVeLEHIRKDLEEKMAAEEQLqALVKEMNQTLQDKTNQID---------LLQAEISE-- 1119
Cdd:TIGR01612 1497 GCKD----EADKNAKAIEKNKEL-FEQYKKDVTELLNKYSAL-AIKNKFAKTKKDSEIIIKeikdahkkfILEAEKSEqk 1570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1120 -NQVIIQKLTTSNTDASDGDS-VALVKETVVISPpgtdsgehwkpeLEEKILALEkekeQLQKKLQEALTSRKAILKKAQ 1197
Cdd:TIGR01612 1571 iKEIKKEKFRIEDDAAKNDKSnKAAIDIQLSLEN------------FENKFLKIS----DIKKKINDCLKETESIEKKIS 1634

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1622909128 1198 EKERHLRE-ELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1238
Cdd:TIGR01612 1635 SFSIDSQDtELKENGDNLNSLQEFLESLKDQKKNIEDKKKEL 1676
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1902-2535 3.99e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.37  E-value: 3.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1902 QIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcvSELEEEKQQLVKEK 1981
Cdd:pfam12128  273 LIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLP 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1982 TkVESEIrkEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQL----QKDCIRYQEKISALERTVKALEFVQTESQKD 2057
Cdd:pfam12128  351 S-WQSEL--ENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIagikDKLAKIREARDRQLAVAEDDLQALESELREQ 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2058 LEITKENLAQAVEHRKKAQAELasfKVLLDDTQSEaarvladnlklkKELQSNKESVKSQMKQKDEDLERR---LEQAEE 2134
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGEL---KLRLNQATAT------------PELLLQLENFDERIERAREEQEAAnaeVERLQS 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2135 KHLKEKKNMQEKLDALRREKVHLEETIGeiqvtlnkkdkEIQQVQENLDSTVAQLAAFTKSMSSL-QDDRDRVIDEAKKW 2213
Cdd:pfam12128  493 ELRQARKRRDQASEALRQASRRLEERQS-----------ALDELELQLFPQAGTLLHFLRKEAPDwEQSIGKVISPELLH 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2214 ErkfSDAIQTKEEEIRLKEENCSVLKDQLRQMSI-----HMEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGEN 2288
Cdd:pfam12128  562 R---TDLDPEVWDGSVGGELNLYGVKLDLKRIDVpewaaSEEELRERLDKAEEALQ----SAREKQAAAEEQLVQANGEL 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2289 KELLSQLEETRHLYHNSQNELAKLESELNILKDQLTD-LSNSLEKCKEQKENLEGIIRQQEADIQNSkfsyeqletdLQA 2367
Cdd:pfam12128  635 EKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKaLAERKDSANERLNSLEAQLKQLDKKHQAW----------LEE 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2368 SRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETL 2447
Cdd:pfam12128  705 QKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2448 NAIKKeNIQQKAQLDSFVKSMSSLQNDRDRIvgdyqQLEERHLSVILEKDQL---IQEAAAENNKLKEEIRGLRSHMDDL 2524
Cdd:pfam12128  785 ERIAV-RRQEVLRYFDWYQETWLQRRPRLAT-----QLSNIERAISELQQQLarlIADTKLRRAKLEMERKASEKQQVRL 858

                          650
                   ....*....|.
gi 1622909128 2525 NSENAKLDAEL 2535
Cdd:pfam12128  859 SENLRGLRCEM 869
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1989-2182 4.20e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 4.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1989 RKEYLEKIQGaQKEPGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERTVKALEFVQTESQKDLEITK--ENLA 2066
Cdd:COG4717     54 EADELFKPQG-RKPELNLKELKELEEELKEAEEKEEEYAEL----QEELEELEEELEELEAELEELREELEKLEklLQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2067 QAVEHRKKAQAELASFKVLLDDTQSEAARVladnlklkKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEK 2146
Cdd:COG4717    129 PLYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1622909128 2147 LDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2182
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENEL 236
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2268-2477 4.21e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2268 SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQ 2347
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2348 EADIQ-NSKFSYEQL----ETDLQASRELtsRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQE 2422
Cdd:COG4942    110 LRALYrLGRQPPLALllspEDFLDAVRRL--QYLKYLAPARREQAEELRADLAELAALRAELEAER-AELEALLAELEEE 186

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909128 2423 EEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDR 2477
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PRK12704 PRK12704
phosphodiesterase; Provisional
 2071-2233 5.30e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.54  E-value: 5.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2071 HRKKAQAELASFKVLLDDTQsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERR--LEQAEEKHLKEKKNMQEKLD 2148
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2149 ALRREKVHLEETIGEiqvtLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDD--RDRVIDEAKKwERKFSDAIQTKEE 2226
Cdd:PRK12704   104 LLEKREEELEKKEKE----LEQKQQELEKKEEELEELIEEQLQELERISGLTAEeaKEILLEKVEE-EARHEAAVLIKEI 178


                   ....*..
gi 1622909128 2227 EIRLKEE 2233
Cdd:PRK12704   179 EEEAKEE 185
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
193-381 5.94e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 5.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  193 QQLQEKEELISTLQAQLSQ-TQAEQAAQVVREKDARFETQVRLheDELLQLVTQadvetemQQKLRVLQRKLEEHEESLV 271
Cdd:COG4913    235 DDLERAHEALEDAREQIELlEPIRELAERYAAARERLAELEYL--RAALRLWFA-------QRRLELLEAELEELRAELA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  272 GRAQVVDLLQQELTAAEQR----------NQILSQQLQQIEAEHNTL-RNTVETEREESKILLEKMELEVAERKLSFHNL 340
Cdd:COG4913    306 RLEAELERLEARLDALREEldeleaqirgNGGDRLEQLEREIERLEReLEERERRRARLEALLAALGLPLPASAEEFAAL 385

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1622909128  341 QEEMRHLLEQLEQ----AGQAQAELESRYSALEQKHKAEMEEKTS 381
Cdd:COG4913    386 RAEAAALLEALEEeleaLEEALAEAEAALRDLRRELRELEAEIAS 430
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 239-453 6.61e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  239 LLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLR---NTVETE 315
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  316 REESKILLEKMELEVAER---------------KLSFHNLQEEMR--HLLEQLEQAGQAQAE-LESRYSALEQKhKAEME 377
Cdd:COG4942     92 IAELRAELEAQKEELAELlralyrlgrqpplalLLSPEDFLDAVRrlQYLKYLAPARREQAEeLRADLAELAAL-RAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128  378 EKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQ 453
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1305-1505 6.62e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 6.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1305 SVAQIKAQLKEIETEKEKLELKISS--TTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQ 1382
Cdd:COG3206    176 ALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1383 IAGLEHLRELQPELDELQKLISEKEEdvsyLSGQLREKEAALTKIQTEIIEQEDLIKA----LHTQLEMQAKEHDERIKQ 1458
Cdd:COG3206    256 LPELLQSPVIQQLRAQLAELEAELAE----LSARYTPNHPDVIALRAQIAALRAQLQQeaqrILASLEAELEALQAREAS 331

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622909128 1459 LQVELCEMKQKPEEIEEESRAKQQIQRKLQAA------LISRKEALKENKSLQ 1505
Cdd:COG3206    332 LQAQLAQLEARLAELPELEAELRRLEREVEVArelyesLLQRLEEARLAEALT 384
46 PHA02562
endonuclease subunit; Provisional
 2540-2776 6.98e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.39  E-value: 6.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2540 EDL--NQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRD----LSKEIESLKVSV 2613
Cdd:PHA02562   157 EDLldISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKTIKAEI 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2614 SQLTRQVTALQEEGtlGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVC------------VQKEAAKKVGEIEDK 2681
Cdd:PHA02562   237 EELTDELLNLVMDI--EDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCptctqqisegpdRITKIKDKLKELQHS 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2682 LKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQsfgrsmsSLQNSRDHANEELDELKR 2761
Cdd:PHA02562   315 LEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEELAKLQD 386

                          250
                   ....*....|....*
gi 1622909128 2762 KYDASLKELAQLKEQ 2776
Cdd:PHA02562   387 ELDKIVKTKSELVKE 401
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2517-2719 8.04e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 8.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2517 LRSHMDDLNSENAKLDAELIQYREDLNQvisikdsqqkqlLEAQLQQNKElKNKYAKLEEKLKESEEANEDLQRSSNALQ 2596
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKELEE------------AEAALEEFRQ-KNGLVDLSEEAKLLLQQLSELESQLAEAR 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2597 EEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVG 2676
Cdd:COG3206    233 AELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1622909128 2677 EIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQ 2719
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2461-3064 8.05e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 8.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2461 LDSFVKSM----SSLQNDRDRIVGDYQQLEERHLSVILEKDQL-----IQEAAAENNKLKEEIRGLRSHMDDLNSENAKL 2531
Cdd:COG4913    209 LDDFVREYmleePDTFEAADALVEHFDDLERAHEALEDAREQIellepIRELAERYAAARERLAELEYLRAALRLWFAQR 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2532 DAELIQYREDLNQvisikdsQQKQLLEAQLQQNKELKNKyAKLEEKLKESEEANEDLQRSsNALQEEKRDLSKEIESLKV 2611
Cdd:COG4913    289 RLELLEAELEELR-------AELARLEAELERLEARLDA-LREELDELEAQIRGNGGDRL-EQLEREIERLERELEERER 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2612 SVSQLTRQVTALQEE--GTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDkLKKELKHL 2689
Cdd:COG4913    360 RRARLEALLAALGLPlpASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS-LERRKSNI 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2690 HHDAGIMRNETETA----EER---VAEL---------------------ARDLVEMEQKLLMVTK--ENKDLTAQIQSFG 2739
Cdd:COG4913    439 PARLLALRDALAEAlgldEAElpfVGELievrpeeerwrgaiervlggfALTLLVPPEHYAAALRwvNRLHLRGRLVYER 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2740 --RSMSSLQNSRDHAN---EELD------------ELKRKYD----ASLKELAQLKE---QQGLL--NRERHALlsettf 2793
Cdd:COG4913    519 vrTGLPDPERPRLDPDslaGKLDfkphpfrawleaELGRRFDyvcvDSPEELRRHPRaitRAGQVkgNGTRHEK------ 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2794 sMDLPEENSLSYLEKLN-QQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQnERDHLWNELEKFRKSE---------- 2862
Cdd:COG4913    593 -DDRRRIRSRYVLGFDNrAKLAALEAELAELEEELAEAEERLEALEAELDALQ-ERREALQRLAEYSWDEidvasaerei 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2863 EGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRplkAQLQEYQDKTKTFQIMQEELR 2942
Cdd:COG4913    671 AELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAE---EELDELQDRLEAAEDLARLEL 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2943 QENLswQHELHQLRMEKssweiHERRMKEQYLMAISDKDQQVSHLQNLIRELRSsssqaqplkvQYQRQASPETSASPDG 3022
Cdd:COG4913    748 RALL--EERFAAALGDA-----VERELRENLEERIDALRARLNRAEEELERAMR----------AFNREWPAETADLDAD 810

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 1622909128 3023 SQNLIYETELLRNQLNDSLKEIHQK--ELRIQQLNSKFSQLLEE 3064
Cdd:COG4913    811 LESLPEYLALLDRLEEDGLPEYEERfkELLNENSIEFVADLLSK 854
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1373-1736 8.24e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.28  E-value: 8.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1373 QQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYL---SGQLREKEAALTKIQTEIIEQEDLiKALHTQLEMQA 1449
Cdd:PLN02939    39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSlrtVMELPQKSTSSDDDHNRASMQRDE-AIAAIDNEQQT 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1450 KEHD-ERIKQLQVE-LCEMKQKPEE-IEEESRAKQQIQRKLQAALiSRKEAL-KENKSLQEELSLARDTIEHLTKSLADV 1525
Cdd:PLN02939   118 NSKDgEQLSDFQLEdLVGMIQNAEKnILLLNQARLQALEDLEKIL-TEKEALqGKINILEMRLSETDARIKLAAQEKIHV 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1526 ESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKE---KLVKEIESLKSS---- 1598
Cdd:PLN02939   197 EILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEErvfKLEKERSLLDASlrel 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1599 --KIAESSEWQEKHKELQkeYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETekqlqeaekem 1673
Cdd:PLN02939   277 esKFIVAQEDVSKLSPLQ--YDCWWEKVENLQDLLDRATNQVEkaaLVLDQNQDLRDKVDKLEASLKEA----------- 343

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 1674 eemkeKMRKFAKSK----QQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKME 1736
Cdd:PLN02939   344 -----NVSKFSSYKvellQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEESKKRSLE 405
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2819-3091 8.45e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 8.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2819 QLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKS--EEGKQRSAAQpatslAEVQSLKKAMSSLQNDRDRL 2896
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLEleELELELEEAQ-----AEEYELLAELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2897 LKELKNLQQQYLQINQEITELRP----LKAQLQEYQDKTKTFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQ 2972
Cdd:COG1196    308 EERRRELEERLEELEEELAELEEeleeLEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2973 YLMAISDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASPETSASPdgsqnliyETELLRNQLNDSLKEIHQKELRIQ 3052
Cdd:COG1196    388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE--------EEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1622909128 3053 QLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLN 3091
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2287-2507 8.87e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 8.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2287 ENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQ 2366
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2367 ASRE-LTSRLHEEINMKEQKMISLLSGKEEAIQVA-----IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2440
Cdd:COG4942    101 AQKEeLAELLRALYRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 2441 NQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAEN 2507
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1312-1989 9.39e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.04  E-value: 9.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1312 QLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQInkQGLEIESLKTASHEAEVRAE----SLQQKLESSQLQIAGLE 1387
Cdd:TIGR00606  427 QADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKEL--QQLEGSSDRILELDQELRKAerelSKAEKNSLTETLKKEVK 504

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1388 HLRELQPELDELQKLISEKEEDVSYLSGQLREKEAaLTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMK 1467
Cdd:TIGR00606  505 SLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEM-LTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKS 583

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1468 QKPEEIEEESRakqQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSlADVESHVSAQNKEKDRVLGRLALLQ 1547
Cdd:TIGR00606  584 KEINQTRDRLA---KLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEIEKSSKQRAMLA 659

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1548 EERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEdkekLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENV 1627
Cdd:TIGR00606  660 GATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQE----FISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGR 735

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1628 SNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLqEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHP 1707
Cdd:TIGR00606  736 QSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL-GTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAK 814

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1708 AGGTakecmeTLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLES----NVSKQANLEATEKHDN 1783
Cdd:TIGR00606  815 LQGS------DLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNElkseKLQIGTNLQRRQQFEE 888

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1784 QMNVTEEATQSIPGETED-QDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1862
Cdd:TIGR00606  889 QLVELSTEVQSLIREIKDaKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGK 968

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1863 E-FSQTLENERNALLSQISTKDGELKLLQEEVSKM--NLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGsi 1939
Cdd:TIGR00606  969 DdYLKQKETELNTVNAQLEECEKHQEKINEDMRLMrqDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQ-- 1046

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1940 gnycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR 1989
Cdd:TIGR00606 1047 ----MQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELR 1092
PRK12704 PRK12704
phosphodiesterase; Provisional
 1659-1802 9.71e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.77  E-value: 9.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1659 KKETEKQLQEAEKEMEEMKEKMRKFAKS-KQQKILELEEENDRLRAEVHpaggtaKEcmetLLSSNASMKEEVERVKMEY 1737
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAiKKEALLEAKEEIHKLRNEFE------KE----LRERRNELQKLEKRLLQKE 95

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909128 1738 ETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQ-----MNVT-EEATQSIPGETEDQ 1802
Cdd:PRK12704    96 ENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQeleriSGLTaEEAKEILLEKVEEE 166
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 685-1017 1.10e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 1.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  685 QDELERLKSQILELELNFHKAQ---EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKEL-SV 760
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSqelSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELeAR 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  761 VTELRAQVRQLEMNLAEAERQRRFDYESQtahhnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 840
Cdd:TIGR02169  767 IEELEEDLHKLEEALNDLEARLSHSRIPE------IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  841 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 920
Cdd:TIGR02169  841 QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  921 EekfsLGVEIKTLKEQLNLLSRAEEAKKEQVEED---NEVVSGLKQNYDEMSPAGLISKEELQhEFDLLKKENEQRKRKL 997
Cdd:TIGR02169  921 E----LKAKLEALEEELSEIEDPKGEDEEIPEEElslEDVQAELQRVEEEIRALEPVNMLAIQ-EYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|
gi 1622909128  998 QAALINRKELLQRVSRLEEE 1017
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKK 1015
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1831-2068 1.12e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 1.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1831 VSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKmnlLNQQIQEelsRV 1910
Cdd:COG3883     12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAE---AEAEIEE---RR 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1911 TKLKETAEEEKddLEERLMNQLAELNGSignycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEirk 1990
Cdd:COG3883     86 EELGERARALY--RSGGSVSYLDVLLGS-----ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAK--- 155

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909128 1991 eyLEKIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2068
Cdd:COG3883    156 --LAELEALKAE--LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2168-2368 1.18e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2168 LNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKfsdaIQTKEEEIRLKEENCSVLKDQLRQMSI 2247
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAE----IDKLQAEIAEAEAEIEERREELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2248 HMEELKINISRLEhdkQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLS 2327
Cdd:COG3883     94 ALYRSGGSVSYLD---VLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1622909128 2328 NSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQAS 2368
Cdd:COG3883    171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAA 211
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1905-2567 1.19e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1905 EELSRVTKLKETAEEEKDDLE---------ERLMNQLAELNgsignYCQDVTD---AQIKNELLESEMKNLKKCVSELEE 1972
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEpirelaeryAAARERLAELE-----YLRAALRlwfAQRRLELLEAELEELRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1973 EKQQLVKEKTKVESEIR--KEYLEKIQGAQKEpgnkshakELQELLKEKQQEVKQLQKDCIRYQEKISALERTV----KA 2046
Cdd:COG4913    310 ELERLEARLDALREELDelEAQIRGNGGDRLE--------QLEREIERLERELEERERRRARLEALLAALGLPLpasaEE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2047 LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDL- 2125
Cdd:COG4913    382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELp 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2126 -----------ERRLEQAEEKHLKEKK-NM---QEKLDALRR--EKVHLEETIGEIQVTLNKKDKEIQQVQEN-----LD 2183
Cdd:COG4913    462 fvgelievrpeEERWRGAIERVLGGFAlTLlvpPEHYAAALRwvNRLHLRGRLVYERVRTGLPDPERPRLDPDslagkLD 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2184 S-----------------------TVAQLAAFTKSMSSL----QDDRDRVIDEAKKWERK----FS--DAIQTKEEEIRL 2230
Cdd:COG4913    542 FkphpfrawleaelgrrfdyvcvdSPEELRRHPRAITRAgqvkGNGTRHEKDDRRRIRSRyvlgFDnrAKLAALEAELAE 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2231 KEENCSVLKDQLRQMSIHMEELKINISRLEH-DKQIWESKAQTEVQLQqkvcdtlqgenkelLSQLEETRHLYHNSQNEL 2309
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRlAEYSWDEIDVASAERE--------------IAELEAELERLDASSDDL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2310 AKLESELNILKDQLTDLsnslekcKEQKENLEGIIRQQEADIqnskfsyEQLETDLQASREltsRLHEEINMKEQKMISL 2389
Cdd:COG4913    688 AALEEQLEELEAELEEL-------EEELDELKGEIGRLEKEL-------EQAEEELDELQD---RLEAAEDLARLELRAL 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2390 LSGK--EEAIQVAIAELRQQHDKEIKELENLLSQeeeenivleeenkkavdKTNQLMETLNAIKKENIQQKAQLDSFVKS 2467
Cdd:COG4913    751 LEERfaAALGDAVERELRENLEERIDALRARLNR-----------------AEEELERAMRAFNREWPAETADLDADLES 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2468 MSSLQNDRDRIVGD-----YQQLEErhlsviLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSE--------------- 2527
Cdd:COG4913    814 LPEYLALLDRLEEDglpeyEERFKE------LLNENSIEFVADLLSKLRRAIREIKERIDPLNDSlkripfgpgrylrle 887

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1622909128 2528 -NAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKEL 2567
Cdd:COG4913    888 aRPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRL 928
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1307-1507 1.26e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1307 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEvfQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSqlqiaGL 1386
Cdd:COG4913    265 AAARERLAELEYLRAALRLWFAQRRLELLEAELE--ELRAELARLEAELERLEARLDALREELDELEAQIRGN-----GG 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1387 EHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1466
Cdd:COG4913    338 DRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1622909128 1467 KQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEE 1507
Cdd:COG4913    418 RRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEA 458
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 2594-2918 1.27e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2594 ALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVcVQKEAAK 2673
Cdd:COG3096    789 ELRAERDELAEQYAKASFDVQKLQRLHQAFSQFVGGHLAVAFAPDPEAELAALRQRRSELERELAQHRAQEQ-QLRQQLD 867

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2674 KVGEIEDKLKKELKHLHHDAgimrneTETAEERVAELARDLVEMEQKLLMVTKENKDLT------AQIQSFGRSMSSLQN 2747
Cdd:COG3096    868 QLKEQLQLLNKLLPQANLLA------DETLADRLEELREELDAAQEAQAFIQQHGKALAqleplvAVLQSDPEQFEQLQA 941

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2748 SRDHANEELDELKRKYDAsLKELAQlkeqqgllnrERHALLSETTFSMdLPEENSLSylEKLNQQLLSKDEQLLHLSSQL 2827
Cdd:COG3096    942 DYLQAKEQQRRLKQQIFA-LSEVVQ----------RRPHFSYEDAVGL-LGENSDLN--EKLRARLEQAEEARREAREQL 1007

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2828 EDSYNQVQSFSKAMASLQNERDHLWNELEKFRK--SEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLK------- 2898
Cdd:COG3096   1008 RQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQelEELGVQADAEAEERARIRRDELHEELSQNRSRRSQLEKqltrcea 1087

                          330       340
                   ....*....|....*....|
gi 1622909128 2899 ELKNLQQQYLQINQEITELR 2918
Cdd:COG3096   1088 EMDSLQKRLRKAERDYKQER 1107
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2285-2918 1.29e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.51  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2285 QGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLegiiRQQEADIQNSKFSYEQLETD 2364
Cdd:PRK01156   137 QGEMDSLISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKL----KSSNLELENIKKQIADDEKS 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2365 LQASRELTSRLHEEINMKEQKMISL------LSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVD 2438
Cdd:PRK01156   213 HSITLKEIERLSIEYNNAMDDYNNLksalneLSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYK 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2439 KTNQLMETLNAIKkeniqqkaQLDSFVKSMSSLQNDrdrivgdyqqleerhlsviLEKDQLIQEAAAENNKLKEEIRGLR 2518
Cdd:PRK01156   293 NRNYINDYFKYKN--------DIENKKQILSNIDAE-------------------INKYHAIIKKLSVLQKDYNDYIKKK 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2519 SHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQkqlleaqlQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEE 2598
Cdd:PRK01156   346 SRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIE--------EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVK 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2599 KRDLSKEIESLKVSVSQLTRqvtalqeegtlgiyhaqlkvKEEELQRLSALLSSSQKRI---TELEEELVcvqKEAAKKV 2675
Cdd:PRK01156   418 LQDISSKVSSLNQRIRALRE--------------------NLDELSRNMEMLNGQSVCPvcgTTLGEEKS---NHIINHY 474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2676 GEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEmeqKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANE- 2754
Cdd:PRK01156   475 NEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEIN---KSINEYNKIESARADLEDIKIKINELKDKHDKYEEi 551

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2755 -------ELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLSSQL 2827
Cdd:PRK01156   552 knrykslKLEDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2828 EDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQY 2907
Cdd:PRK01156   632 NNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRI 711

                          650
                   ....*....|.
gi 1622909128 2908 LQINQEITELR 2918
Cdd:PRK01156   712 NELSDRINDIN 722
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2562-3083 1.45e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 1.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2562 QQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLS-------KEIESLKVSVSQLTRQVTALQEEGTLGIYHA 2634
Cdd:pfam15921  138 QSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMlshegvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRS 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2635 QLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLhhdagIMRNETE-TAEERVAELARD 2713
Cdd:pfam15921  218 LGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQL-----ISEHEVEiTGLTEKASSARS 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2714 LVEMEQKLLMVTKENKdlTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELA------------------QLKE 2775
Cdd:pfam15921  293 QANSIQSQLEIIQEQA--RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlanseltearterdQFSQ 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2776 QQGLLNRERHALLSETTfsmdlPEENSLSYLEKLNQQLLSKDE----QLLHLSSQLEDSYNQVQ---------------S 2836
Cdd:pfam15921  371 ESGNLDDQLQKLLADLH-----KREKELSLEKEQNKRLWDRDTgnsiTIDHLRRELDDRNMEVQrleallkamksecqgQ 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2837 FSKAMASLQNERDHLWN--------------------ELEKFRKSEEGKQRSAAQPATSLAE----VQSLKKAMSSLQND 2892
Cdd:pfam15921  446 MERQMAAIQGKNESLEKvssltaqlestkemlrkvveELTAKKMTLESSERTVSDLTASLQEkeraIEATNAEITKLRSR 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2893 RDRLLKELKNLQQQYLQINQEITELRPLKAQLQEyqdKTKTFQIMQEELRQ-ENLSWQH-------ELHQLRMEKsswEI 2964
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAE---KDKVIEILRQQIENmTQLVGQHgrtagamQVEKAQLEK---EI 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2965 HERRMKEQYLMAISDKDQQVshlqnlIRELRSSSSQAQPLKVQYQRQASPETSASPDGSQ---NLIYETELLRNQLNdSL 3041
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAK------IRELEARVSDLELEKVKLVNAGSERLRAVKDIKQerdQLLNEVKTSRNELN-SL 672

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1622909128 3042 KEihQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQ 3083
Cdd:pfam15921  673 SE--DYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2009-2533 1.84e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 1.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2009 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERtvkalefvqtesqkdleiTKENLAQAVEHRKKAQAELASFKVLLDD 2088
Cdd:PRK02224   201 EKDLHERLNGLESELAELDEEIERYEEQREQARE------------------TRDEADEVLEEHEERREELETLEAEIED 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2089 TQSEAARVladnlklKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK--EKKNMQEKLDALRREKVHLEETIGEIQV 2166
Cdd:PRK02224   263 LRETIAET-------EREREELAEEVRDLRERLEELEEERDDLLAEAGLDdaDAEAVEARREELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2167 TLNKKDKEIQQVQENldstVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMS 2246
Cdd:PRK02224   336 AAQAHNEEAESLRED----ADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2247 IHMEELKINISRLEhdkqiwESKAQTEVQLQQkVCDTLQgENKELLSQ---------LEETRHL--YHNSQNELAKLESE 2315
Cdd:PRK02224   412 DFLEELREERDELR------EREAELEATLRT-ARERVE-EAEALLEAgkcpecgqpVEGSPHVetIEEDRERVEELEAE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2316 LNILKDQLTDLSNSL-------------EKCKEQKENLEGIIRQQEADIQNSKFSYEQ-------LETDLQASRELTSRL 2375
Cdd:PRK02224   484 LEDLEEEVEEVEERLeraedlveaedriERLEERREDLEELIAERRETIEEKRERAEElreraaeLEAEAEEKREAAAEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2376 HEEINmKEQKMISLLSGKEEAIQVAIAELRQqhdkeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLnaikKENI 2455
Cdd:PRK02224   564 EEEAE-EAREEVAELNSKLAELKERIESLER-----IRTLLAAIADAEDEIERLREKREALAELNDERRERL----AEKR 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2456 QQKAQLDSFVKS--MSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAENNKLkEEIRGLRSHMDDLNSENAKLDA 2533
Cdd:PRK02224   634 ERKRELEAEFDEarIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL-EELEELRERREALENRVEALEA 712
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2395-2622 1.90e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2395 EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKaVDKTNQLMETLNAIKKENIQQKAQLDsfvKSMSSLQND 2474
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR-IRALEQELAALEAELAELEKEIAELR---AELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2475 RDRIVGDYQQLEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdaeliqyrEDLNQVISIKDSQQK 2554
Cdd:COG4942    106 LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909128 2555 QLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTA 2622
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2287-2664 1.95e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2287 ENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFS--YEQLETD 2364
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPerLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2365 LQASREL---TSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDkEIKELENLLSQEEEENIVLEEENKKAVDKTN 2441
Cdd:COG4717    155 LEELRELeeeLEELEAELAELQEELEELLEQLSLATEEELQDLAEELE-ELQQRLAELEEELEEAQEELEELEEELEQLE 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2442 QLMETLNAIKKEN---------------IQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAE 2506
Cdd:COG4717    234 NELEAAALEERLKearlllliaaallalLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2507 NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKElknkyakleEKLKESEEANE 2586
Cdd:COG4717    314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA---------ALLAEAGVEDE 384

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909128 2587 DLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEEL 2664
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAEL 462
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 977-1627 1.99e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.06  E-value: 1.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  977 EELQHEFDLLKKENEQRKRklqaalinrkellqrvsrLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSK 1056
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLES------------------AELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQ 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1057 CQEIEISLKQTISEKEVELEHIRKDLEekmAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTT------- 1129
Cdd:pfam12128  299 WKEKRDELNGELSAADAAVAKDRSELE---ALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGkhqdvta 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1130 ------SNTDASDGDSVALVKETVVISPPGTDSG------------EHWKPELEEKILALEKEKEQLQKKLQEAltsrKA 1191
Cdd:pfam12128  376 kynrrrSKIKEQNNRDIAGIKDKLAKIREARDRQlavaeddlqaleSELREQLEAGKLEFNEEEYRLKSRLGEL----KL 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1192 ILKKAQEKErHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQiQVRESIDGKLPSPDQ--QEWCSPTPGLEEPL 1269
Cdd:pfam12128  452 RLNQATATP-ELLLQLENFDERIERAREEQEAANAEVERLQSELRQAR-KRRDQASEALRQASRrlEERQSALDELELQL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1270 FKateQHHTQPVLESNLCPDWPSH-----------------SEDASALQGGTSVAQIKAQLK------------EIETEK 1320
Cdd:pfam12128  530 FP---QAGTLLHFLRKEAPDWEQSigkvispellhrtdldpEVWDGSVGGELNLYGVKLDLKridvpewaaseeELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1321 EKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESL--QQKLESSQLQIAGLEHLRELQPELDE 1398
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLfdEKQSEKDKKNKALAERKDSANERLNS 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1399 L---QKLISEKEEDVS-YLSGQLRE----KEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERI-KQLQVELCEMKQK 1469
Cdd:pfam12128  687 LeaqLKQLDKKHQAWLeEQKEQKREarteKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALeTWYKRDLASLGVD 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1470 PEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDtieHLTKSLADVESHVSaqnkekdRVLGRLALLQEE 1549
Cdd:pfam12128  767 PDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRP---RLATQLSNIERAIS-------ELQQQLARLIAD 836

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1550 ----RDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKL-VKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSY 1624
Cdd:pfam12128  837 tklrRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDAnSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHF 916


                   ...
gi 1622909128 1625 ENV 1627
Cdd:pfam12128  917 KNV 919
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2704-2928 1.99e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2704 EERVAELARDLVEMEQKLLMVTKENK--DLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQqglln 2781
Cdd:COG3206    181 EEQLPELRKELEEAEAALEEFRQKNGlvDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA----- 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2782 rerhallsettfsmdLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDhlwnelekfrks 2861
Cdd:COG3206    256 ---------------LPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQ------------ 308

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 2862 eegkqrsaaqpatslaevQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQ 2928
Cdd:COG3206    309 ------------------QEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2016-2227 2.06e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 2.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2016 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAAR 2095
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2096 VLADNLKLKKELQS-------NKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTL 2168
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909128 2169 NKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEE 2227
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2736-2943 2.50e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2736 QSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLnrerhallsettfsmDLPEENSLsylekLNQQLLS 2815
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLV---------------DLSEEAKL-----LLQQLSE 223

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2816 KDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWN--ELEKFRKSEEGKQRSAAQPATSLAE----VQSLKKAMSSL 2889
Cdd:COG3206    224 LESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARYTPnhpdVIALRAQIAAL 303

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909128 2890 QNDRDRLLKE-LKNLQQQYLQINQEITELRplkAQLQEYQDKTKTFQIMQEELRQ 2943
Cdd:COG3206    304 RAQLQQEAQRiLASLEAELEALQAREASLQ---AQLAQLEARLAELPELEAELRR 355
PRK11281 PRK11281
mechanosensitive channel MscK;
186-510 2.59e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.75  E-value: 2.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  186 KEFVMMKQQLQEKEELISTLQAQLSQTQAeQAAQVVREkdaRFETqvrLHEDELLQLVTQadVETEMQQklrvLQRKLEE 265
Cdd:PRK11281    80 EETEQLKQQLAQAPAKLRQAQAELEALKD-DNDEETRE---TLST---LSLRQLESRLAQ--TLDQLQN----AQNDLAE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  266 HEESLVGRAQVVDLLQQELTAAEQRnqilsqqlqqIEAEHNTLRNTVETEREESKILLEKMELEvaerkLSFHNLQEEMR 345
Cdd:PRK11281   147 YNSQLVSLQTQPERAQAALYANSQR----------LQQIRNLLKGGKVGGKALRPSQRVLLQAE-----QALLNAQNDLQ 211

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  346 HLL----EQLEQAGQAQAELESRYSALEQKHKAEMEEKTSH---ILSlQKTGQELQSACDALKDQNSKLLQDKDEQAVQS 418
Cdd:PRK11281   212 RKSlegnTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAINSkrlTLS-EKTVQEAQSQDEAARIQANPLVAQELEINLQL 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  419 AQT-IEQLE--DQLQQKSKEISQFLNRlpLQQhetasqtcfpdvynegTQAVTEENIASLQkrvvelenekGALLLSSIE 495
Cdd:PRK11281   291 SQRlLKATEklNTLTQQNLRVKNWLDR--LTQ----------------SERNIKEQISVLK----------GSLLLSRIL 342

                          330       340
                   ....*....|....*....|
gi 1622909128  496 LEELKA-----ENEKLSSQI 510
Cdd:PRK11281   343 YQQQQAlpsadLIEGLADRI 362
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 684-1119 2.71e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.77  E-value: 2.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  684 HQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSVVTE 763
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  764 LRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQL- 842
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLl 494

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  843 ----QNKESEVLEGAERVRHISSKVEELSQALS---------QKELEIAKMDQLLLEKKRDVETLQQTIEE-KDQQVTEI 908
Cdd:COG1196    495 llleAEADYEGFLEGVKAALLLAGLRGLAGAVAvligveaayEAALEAALAAALQNIVVEDDEVAAAAIEYlKAAKAGRA 574

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  909 SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspaGLISKEELQHEFDLLKK 988
Cdd:COG1196    575 TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA---ALRRAVTLAGRLREVTL 651

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  989 ENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKcvtsKCQEIEISLKQTI 1068
Cdd:COG1196    652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE----ERLEEELEEEALE 727

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622909128 1069 SEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISE 1119
Cdd:COG1196    728 EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2138-2332 2.75e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2138 KEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKF 2217
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2218 SDAI-------QTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESK---AQTEVQLQQKVCDTLQGE 2287
Cdd:COG4942    107 AELLralyrlgRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALraeLEAERAELEALLAELEEE 186

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1622909128 2288 NKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEK 2332
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 687-1244 2.87e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 2.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  687 ELERLKSQILELELNFHKAQE---IYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV-VT 762
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEErlaKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKeFA 381

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  763 ELRAQVRQLEMNLAEAERQRrfdYESQTAHHNL------LTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 836
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREI---NELKRELDRLqeelqrLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  837 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVE-----------TLQQTIEEKDQQV 905
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEvlkasiqgvhgTVAQLGSVGERYA 538

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  906 TEISFSMTEKMVQLNEEKFSLGVE-IKTLKEQ---------LNLLSRAE-------------------------EAKKEQ 950
Cdd:TIGR02169  539 TAIEVAAGNRLNNVVVEDDAVAKEaIELLKRRkagratflpLNKMRDERrdlsilsedgvigfavdlvefdpkyEPAFKY 618

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  951 VEEDNEVVSGLKQNYDEMSPAGLISKEElqhefDLLKKENEQR--KRKLQAALINRKELLQRVSRLEEELANLKDQskKE 1028
Cdd:TIGR02169  619 VFGDTLVVEDIEAARRLMGKYRMVTLEG-----ELFEKSGAMTggSRAPRGGILFSRSEPAELQRLRERLEGLKRE--LS 691

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1029 IPLSESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTN 1108
Cdd:TIGR02169  692 SLQSELRRIENRLDELSQELSD-------------ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1109 QIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPPGTDSGEHWKP---ELEEKILALEKEKEQLQKKLQE- 1184
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEArlrEIEQKLNRLTLEKEYLEKEIQEl 838

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909128 1185 -----ALTSRKAILKKAQE----KERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRE 1244
Cdd:TIGR02169  839 qeqriDLKEQIKSIEKEIEnlngKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE 907
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1465-2191 3.25e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.29  E-value: 3.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1465 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLArdtieHLTKSLADVESHVSAQNKEKDRVLGRL- 1543
Cdd:pfam12128  215 KSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLS-----HLHFGYKSDETLIASRQEERQETSAELn 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1544 ALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKE-IESLKSSKIAESSeWQEKHKELQKEYEILLQ 1622
Cdd:pfam12128  290 QLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDAdIETAAADQEQLPS-WQSELENLEERLKALTG 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1623 SYENVSNEAERIQHVVeaVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKfakSKQQKILELEEENDRLR 1702
Cdd:pfam12128  369 KHQDVTAKYNRRRSKI--KEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELRE---QLEAGKLEFNEEEYRLK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1703 AEVHPAGG--TAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEK---DSLSEEvQDLKHQLES---NVSKQAN 1774
Cdd:pfam12128  444 SRLGELKLrlNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELrqaRKRRDQ-ASEALRQASrrlEERQSAL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1775 LEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPAC-SESVPSENSANPAVSEDVSS------HDEINNYLQQIDQL 1847
Cdd:pfam12128  523 DELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHrTDLDPEVWDGSVGGELNLYGvkldlkRIDVPEWAASEEEL 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1848 KERIAGLEEEKQKNKEFSQTLEnernallSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTklketaeEEKDDLEER 1927
Cdd:pfam12128  603 RERLDKAEEALQSAREKQAAAE-------EQLVQANGELEKASREETFARTALKNARLDLRRLF-------DEKQSEKDK 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1928 LMNQLAELNGSIGNYCQDVtDAQIKneLLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgAQKEPGNKS 2007
Cdd:pfam12128  669 KNKALAERKDSANERLNSL-EAQLK--QLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLK-AAIAARRSG 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2008 HAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD 2087
Cdd:pfam12128  745 AKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAIS 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2088 DTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER-RLEQAEEKHLKEKKNMQEkldaLRREKVHLEETIGEIQV 2166
Cdd:pfam12128  825 ELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGlRCEMSKLATLKEDANSEQ----AQGSIGERLAQLEDLKL 900

                          730       740
                   ....*....|....*....|....*
gi 1622909128 2167 TLNKKDKEIQQVQENLDSTVAQLAA 2191
Cdd:pfam12128  901 KRDYLSESVKKYVEHFKNVIADHSG 925
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2746-3001 3.30e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2746 QNSRDHANEELDELKRKYDASLKELAQLKEQQgllnrerhallsettfsmdlpeenslsylEKLNQQLLSKDEQLLHLSS 2825
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEE-----------------------------KALLKQLAALERRIAALAR 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2826 QLEDSYNQVQSFSKAMASLQNERDHLWNELEKfRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRD-RLLKEL-KNL 2903
Cdd:COG4942     70 RIRALEQELAALEAELAELEKEIAELRAELEA-QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRlQYLKYLaPAR 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2904 QQQYLQINQEITELRPLKAQLQEYQDKtktfqimQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQ 2983
Cdd:COG4942    149 REQAEELRADLAELAALRAELEAERAE-------LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221

                          250
                   ....*....|....*...
gi 1622909128 2984 VSHLQNLIRELRSSSSQA 3001
Cdd:COG4942    222 AEELEALIARLEAEAAAA 239
PRK09039 PRK09039
peptidoglycan -binding protein;
2695-2830 3.34e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.65  E-value: 3.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2695 IMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIqsfgrsmSSLQNSRDHANEELDELKRKYDASLKELAQLK 2774
Cdd:PRK09039    43 FLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSV-------ANLRASLSAAEAERSRLQALLAELAGAGAAAE 115

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128 2775 EQQGLLNRErhaLLSETTFSmdlpeENSLSYLEKLNQQLLSKDEQLLHLSSQLEDS 2830
Cdd:PRK09039   116 GRAGELAQE---LDSEKQVS-----ARALAQVELLNQQIAALRRQLAALEAALDAS 163
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1304-1497 3.45e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 3.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1304 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLES--SQL 1381
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEraRAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1382 QIAG------------------LEHLRELQPELDELQKLISEKEEDVsylsGQLREKEAALTKIQTEIIEQEDLIKALHT 1443
Cdd:COG3883     96 YRSGgsvsyldvllgsesfsdfLDRLSALSKIADADADLLEELKADK----AELEAKKAELEAKLAELEALKAELEAAKA 171

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622909128 1444 QLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEA 1497
Cdd:COG3883    172 ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2039-2208 3.46e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 42.67  E-value: 3.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2039 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2114
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2115 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2171
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1622909128 2172 DKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2208
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2319-3185 3.70e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 3.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2319 LKDQLTDLSNSLEKCKE---QKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKEE 2395
Cdd:TIGR00606  222 IRDQITSKEAQLESSREivkSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2396 AIQvaiaELRQQHDKEIKELENLLSQEeeenivleeenKKAVDKTNQLMETLNAIKKENIQQKAQLdsfvksmsSLQNDR 2475
Cdd:TIGR00606  302 QLN----DLYHNHQRTVREKERELVDC-----------QRELEKLNKERRLLNQEKTELLVEQGRL--------QLQADR 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2476 DRIVGDYQQLEERHLSVILEKDQLIQEAAAENnKLKEEIRGLRSHMDDLNSENAKLDAELiQYREDLNQVISIKDSQQKQ 2555
Cdd:TIGR00606  359 HQEHIRARDSLIQSLATRLELDGFERGPFSER-QIKNFHTLVIERQEDEAKTAAQLCADL-QSKERLKQEQADEIRDEKK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2556 LLEAQLQQNKEL----KNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESlkVSVSQLTRQVTALQEEG---- 2627
Cdd:TIGR00606  437 GLGRTIELKKEIlekkQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKN--SLTETLKKEVKSLQNEKadld 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2628 -TLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIED-KLKKELKHLHHDagiMRNETETAEE 2705
Cdd:TIGR00606  515 rKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfPNKKQLEDWLHS---KSKEINQTRD 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2706 RVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHaNEELDELKRKYDASLKELAQLKEQQGLLNRERH 2785
Cdd:TIGR00606  592 RLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE-ESDLERLKEEIEKSSKQRAMLAGATAVYSQFIT 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2786 ALLSETTFSMDL------PEENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR 2859
Cdd:TIGR00606  671 QLTDENQSCCPVcqrvfqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELR 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2860 KSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEyQDKTKTFQimqe 2939
Cdd:TIGR00606  751 NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQG-SDLDRTVQ---- 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2940 ELRQENLSWQHELhqlrmEKSSWEIHERRMkeqylmAISDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQAspetsas 3019
Cdd:TIGR00606  826 QVNQEKQEKQHEL-----DTVVSKIELNRK------LIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFE------- 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 3020 pDGSQNLIYETELLRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQhygDLLNHCAVLEKQ 3099
Cdd:TIGR00606  888 -EQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVK---NIHGYMKDIENK 963

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 3100 VQELQAVSKEKGPLNIDVApGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLC-----NTRQEVNELRKLLEEERDQRVA 3174
Cdd:TIGR00606  964 IQDGKDDYLKQKETELNTV-NAQLEECEKHQEKINEDMRLMRQDIDTQKIQERwlqdnLTLRKRENELKEVEEELKQHLK 1042

                          890
                   ....*....|.
gi 1622909128 3175 AENALSLAEEQ 3185
Cdd:TIGR00606 1043 EMGQMQVLQMK 1053
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1163-1239 3.84e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 3.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1163 ELEEKILALEKEKEQLQKKLQEALTSRKAILKK----AQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1238
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDelaeLEEELEALKARWEAEKELIEEIQELKEELEQRYGKIPELEKEL 494


                   .
gi 1622909128 1239 Q 1239
Cdd:COG0542    495 A 495
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1453-1705 4.22e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 4.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1453 DERIKQLQ----VELCEMKQK--PEEIEEESRAkqqiQRKLQAALISRKEALKENKSLQEELSLAR-----DTIEHLTKS 1521
Cdd:PRK05771    19 DEVLEALHelgvVHIEDLKEElsNERLRKLRSL----LTKLSEALDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1522 LADVESHVSAQNKEKDRvlgrlalLQEERDKLITEMDR-SLLENQSLS----GSCESLKLALEGLTEDKEKLVKEIESLK 1596
Cdd:PRK05771    95 LEKIEKEIKELEEEISE-------LENEIKELEQEIERlEPWGNFDLDlsllLGFKYVSVFVGTVPEDKLEELKLESDVE 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1597 SSKIAESSEwqEK-------HKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELygklrsteankketekqlQEA 1669
Cdd:PRK05771   168 NVEYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL------------------EEI 227

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1622909128 1670 EKEMEEMKEKMRKFAKSKQQKILELEE--ENDRLRAEV 1705
Cdd:PRK05771   228 EKERESLLEELKELAKKYLEELLALYEylEIELERAEA 265
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1916-2147 4.29e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 4.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1916 TAEEEKDDLEERLMN----QLAELNGSIGNYcqdvtdaqiKNELLESEMKNLKKCVSELEEEKQqlvKEKTKVESEIRKE 1991
Cdd:PRK05771    13 TLKSYKDEVLEALHElgvvHIEDLKEELSNE---------RLRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1992 YLEKIQGAQKEPGNKShakELQELLKEKQQEVKQLQKDCIRYQEKISALE---------------RTVKA---------- 2046
Cdd:PRK05771    81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELENEIKELEQEIERLEpwgnfdldlslllgfKYVSVfvgtvpedkl 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2047 LEFVQTESQKDLEITKEN-------LAQAVEHRKKAQAELASFKVLLDDTQSE--AARVLADNLKLKKELQSNKESVKSQ 2117
Cdd:PRK05771   158 EELKLESDVENVEYISTDkgyvyvvVVVLKELSDEVEEELKKLGFERLELEEEgtPSELIREIKEELEEIEKERESLLEE 237

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1622909128 2118 MKQKDEDLERRLEQAEEK--HLKEKKNMQEKL 2147
Cdd:PRK05771   238 LKELAKKYLEELLALYEYleIELERAEALSKF 269
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1842-1995 4.35e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 4.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1842 QQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE------ 1915
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1916 ---TAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1992
Cdd:COG1579     97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                   ...
gi 1622909128 1993 LEK 1995
Cdd:COG1579    177 LAL 179
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1317-1514 4.44e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 4.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1317 ETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAglehlrELQPEL 1396
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIE------ERREEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1397 DELQKLISEKEEDVSYLS-----------------------------GQLREKEAALTKIQTEIIEQEDLIKALHTQLEM 1447
Cdd:COG3883     89 GERARALYRSGGSVSYLDvllgsesfsdfldrlsalskiadadadllEELKADKAELEAKKAELEAKLAELEALKAELEA 168

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 1448 QAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDT 1514
Cdd:COG3883    169 AKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1370-1599 5.10e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 5.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1370 ESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALtkIQTEIIEQEDLIKALHTQLEmqa 1449
Cdd:COG4913    238 ERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELE--- 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1450 kEHDERIKQLQVELCEMKQKPEEIeeESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHV 1529
Cdd:COG4913    313 -RLEARLDALREELDELEAQIRGN--GGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1530 SAQnkeKDRVLGRLALLQEERDKLITemdrsllenqslsgsceslklALEGLTEDKEKLVKEIESLKSSK 1599
Cdd:COG4913    390 AAL---LEALEEELEALEEALAEAEA---------------------ALRDLRRELRELEAEIASLERRK 435
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1306-1556 5.19e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 5.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1306 VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAG 1385
Cdd:COG4372     47 LEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQD 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1386 LEHLR-ELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIieQEDLIKALHTQLEMQAKEHDERIKQLQVELC 1464
Cdd:COG4372    127 LEQQRkQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL--QALSEAEAEQALDELLKEANRNAEKEEELAE 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1465 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLA 1544
Cdd:COG4372    205 AEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALE 284

                          250
                   ....*....|..
gi 1622909128 1545 LLQEERDKLITE 1556
Cdd:COG4372    285 LEALEEAALELK 296
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1308-1669 5.46e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.70  E-value: 5.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1308 QIKAQLKEIETE-----KEKLELKISSTTSELTKKSEEVFQLQDQ-------INKQGLEIESLKTASHEAEVRAESLQQK 1375
Cdd:TIGR04523  285 ELEKQLNQLKSEisdlnNQKEQDWNKELKSELKNQEKKLEEIQNQisqnnkiISQLNEQISQLKKELTNSESENSEKQRE 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1376 LESSQLQIAGLEhlRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQT------EIIEQEDLIKALHTQLEMQA 1449
Cdd:TIGR04523  365 LEEKQNEIEKLK--KENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKlqqekeLLEKEIERLKETIIKNNSEI 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1450 KEHDERIKQLQVELCEMKQKPEEIEEE----SRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADV 1525
Cdd:TIGR04523  443 KDLTNQDSVKELIIKNLDNTRESLETQlkvlSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSL 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1526 ESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKL-----ALEGLTEDKEKLVKEIESLKSSKI 1600
Cdd:TIGR04523  523 KEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELkqtqkSLKKKQEEKQELIDQKEKEKKDLI 602

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909128 1601 AESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1669
Cdd:TIGR04523  603 KEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKES 671
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 833-1047 5.65e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 5.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  833 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM 912
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  913 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagliskEELQHEFDLLKKENE 991
Cdd:COG3883     96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAEL--------EAKLAELEALKAELE 167

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128  992 QRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKE 1047
Cdd:COG3883    168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 253-1086 5.78e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.65  E-value: 5.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  253 QQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAE 332
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  333 RKLSFHNLQEEMRHLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKD 412
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  413 EQAVQSAQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQTCFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLS 492
Cdd:pfam02463  336 EIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  493 SIELEELKAENEKLSSQITLLEAQNRIGEADREVSEISIVDDAnkrsssTEESGQDVLENTFSQKHKELSVLLLEMKEAQ 572
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQEL------KLLKDELELKKSEDLLKETQLVKLQEQLELL 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  573 EEIAFLK--LQLQGKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDTGQNFPLMPNEESSLPAVEKEQASTEHQNRT 650
Cdd:pfam02463  490 LSRQKLEerSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRA 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  651 SEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEF 730
Cdd:pfam02463  570 LTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLR 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  731 KKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLSIEAKS- 809
Cdd:pfam02463  650 KGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQe 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  810 KDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKR 889
Cdd:pfam02463  730 AQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEE 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  890 DVETLQQT------------IEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEV 957
Cdd:pfam02463  810 LKEEAELLeeeqllieqeekIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELE 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  958 VSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE-LANLKDQSKKEIPLSESER 1036
Cdd:pfam02463  890 SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEkEENNKEEEEERNKRLLLAK 969

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1037 GEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKM 1086
Cdd:pfam02463  970 EELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRL 1019
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2502-2971 5.82e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 5.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2502 EAAAEN-NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQL--LEAQLQQNKELKNKYAKLEEKL 2578
Cdd:PRK03918   161 ENAYKNlGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELpeLREELEKLEKEVKELEELKEEI 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2579 KESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQE-----------EGTLGIYHAQLKVKEEELQRLS 2647
Cdd:PRK03918   241 EELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKElkekaeeyiklSEFYEEYLDELREIEKRLSRLE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2648 ALLSSSQKRITELE------EELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKL 2721
Cdd:PRK03918   321 EEINGIEERIKELEekeerlEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2722 LMVTKENKDLTAQIQSFGRSMSSLQNS---------------RDHANEELDELKRKYDASLKELAqlKEQQGLLNRERHA 2786
Cdd:PRK03918   401 EEIEEEISKITARIGELKKEIKELKKAieelkkakgkcpvcgRELTEEHRKELLEEYTAELKRIE--KELKEIEEKERKL 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2787 LLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQL-LHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFrksEEGK 2865
Cdd:PRK03918   479 RKELRELEKVLKKESELIKLKELAEQLKELEEKLkKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL---EELK 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2866 QRSAAqpatslaevqsLKKAMSSLQNDRDRLLKELKNLQQQYL-QINQEITELRPLKAQLQEYQDKTKTFQIMQEELRQE 2944
Cdd:PRK03918   556 KKLAE-----------LEKKLDELEEELAELLKELEELGFESVeELEERLKELEPFYNEYLELKDAEKELEREEKELKKL 624

                          490       500
                   ....*....|....*....|....*..
gi 1622909128 2945 NLSWQHELHQLRMEKSSWEIHERRMKE 2971
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEE 651
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 855-1431 6.20e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 6.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  855 RVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTE---KMVQLNEEKFSLGVEIK 931
Cdd:TIGR04523   34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKnkdKINKLNSDLSKINSEIK 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  932 TLKEQLNL----LSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAGLI------SKEELQHEFDLLKKENEQRK------- 994
Cdd:TIGR04523  114 NDKEQKNKleveLNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKyndlkkQKEELENELNLLEKEKLNIQknidkik 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  995 ---RKLQAALINRKELLQRVSRLEEELANLKDQS---KKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIeislKQTI 1068
Cdd:TIGR04523  194 nklLKLELLLSNLKKKIQKNKSLESQISELKKQNnqlKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI----KKQL 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1069 SEKEVELEHIRKDLEEKMAAEEQLQA------------LVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTtsntdasd 1136
Cdd:TIGR04523  270 SEKQKELEQNNKKIKELEKQLNQLKSeisdlnnqkeqdWNKELKSELKNQEKKLEEIQNQISQNNKIISQLN-------- 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1137 gDSVALVKETVVISppgTDSGEHWKPELEEKILALEKEKEQLQKKLQE--ALTSRKAIL----KKAQEKERHLREELKQQ 1210
Cdd:TIGR04523  342 -EQISQLKKELTNS---ESENSEKQRELEEKQNEIEKLKKENQSYKQEikNLESQINDLeskiQNQEKLNQQKDEQIKKL 417

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1211 KDDYNRLQEQFDEQSKENENIGDQLRQL--QIQVRESIDGKLPSPDQQewcsptpgLEEPLFKATEQHHTQPVLESNLCP 1288
Cdd:TIGR04523  418 QQEKELLEKEIERLKETIIKNNSEIKDLtnQDSVKELIIKNLDNTRES--------LETQLKVLSRSINKIKQNLEQKQK 489

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1289 DWPSHSEDASALQGGTSvaQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINK--QGLEIESLKTASHEAE 1366
Cdd:TIGR04523  490 ELKSKEKELKKLNEEKK--ELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKN 567

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909128 1367 VRAESLQQ---KLESSQLQIAglEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEI 1431
Cdd:TIGR04523  568 KEIEELKQtqkSLKKKQEEKQ--ELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSII 633
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 2165-2569 6.24e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.35  E-value: 6.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2165 QVTLNKKDKEIQQVQEnLDSTVAQLAAFTKSMSSLQDDRdRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVlkDQLRQ 2244
Cdd:PRK10929    34 QAKAAKTPAQAEIVEA-LQSALNWLEERKGSLERAKQYQ-QVIDNFPKLSAELRQQLNNERDEPRSVPPNMST--DALEQ 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2245 msihmEELKINISRLEHDKQiweskAQTEVQLQQKVCDTL------QGENKELLSQLEETRHLYHN-----SQNELAKLE 2313
Cdd:PRK10929   110 -----EILQVSSQLLEKSRQ-----AQQEQDRAREISDSLsqlpqqQTEARRQLNEIERRLQTLGTpntplAQAQLTALQ 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2314 SELNILKDQLtdlsNSLEKCKEQKENLEGIIRQQeadIQNSKFSYEQLETDLQAsreltsrLHEEINMKEQKMISLLSGK 2393
Cdd:PRK10929   180 AESAALKALV----DELELAQLSANNRQELARLR---SELAKKRSQQLDAYLQA-------LRNQLNSQRQREAERALES 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2394 EEAIQVAIAELRQQHDKEIK---ELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKkeniQQKAQLDSfvksmss 2470
Cdd:PRK10929   246 TELLAEQSGDLPKSIVAQFKinrELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTLR----EQSQWLGV------- 314

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2471 lqndrDRIVGDYQQLEERHLSVILEKDQLIQEAAaennklkeEIRGLRSHMDDLNSENAKLDaeliQYREDLNQVISikd 2550
Cdd:PRK10929   315 -----SNALGEALRAQVARLPEMPKPQQLDTEMA--------QLRVQRLRYEDLLNKQPQLR----QIRQADGQPLT--- 374

                          410
                   ....*....|....*....
gi 1622909128 2551 SQQKQLLEAQLQQNKELKN 2569
Cdd:PRK10929   375 AEQNRILDAQLRTQRELLN 393
mukB PRK04863
chromosome partition protein MukB;
2701-3003 6.45e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.64  E-value: 6.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2701 ETAEERVAELARDLVEMEQKllmvtkenkdlTAQIQSFGRSMSSLQ---NSRDHANEELDELKRKYDASLKELAQLKEQQ 2777
Cdd:PRK04863   890 ETLADRVEEIREQLDEAEEA-----------KRFVQQHGNALAQLEpivSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQA 958

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2778 GLLN--RERHALLSETTFSMDLPEENSLSylEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNEL 2855
Cdd:PRK04863   959 FALTevVQRRAHFSYEDAAEMLAKNSDLN--EKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQML 1036

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2856 ekfrksEEGKQRSAAQ--PATSLAEVQslkkamssLQNDRDRLLKELKNLQQQYLQINQEIT----ELRPLKAQLQEYQd 2929
Cdd:PRK04863  1037 ------QELKQELQDLgvPADSGAEER--------ARARRDELHARLSANRSRRNQLEKQLTfceaEMDNLTKKLRKLE- 1101

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2930 ktKTFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERR---MKEQYLMAISDKDQ-----QVSHLQNLIRELRSSSSQA 3001
Cdd:PRK04863  1102 --RDYHEMREQVVNAKAGWCAVLRLVKDNGVERRLHRRElayLSADELRSMSDKALgalrlAVADNEHLRDVLRLSEDPK 1179


                   ..
gi 1622909128 3002 QP 3003
Cdd:PRK04863  1180 RP 1181
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 155-427 6.86e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 42.51  E-value: 6.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  155 EKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKefvmmKQQL-QEKEEL---ISTLQAQLSQT-QAEQAAQVVREKDArFE 229
Cdd:NF012221  1539 ESSQQADAVSKHAKQDDAAQNALADKERAEAD-----RQRLeQEKQQQlaaISGSQSQLESTdQNALETNGQAQRDA-IL 1612

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  230 TQVRLHEDELLQLVTQADV---------ETEMQQKLRVLQRKLEEHEESLVGRAQVVdllQQELTAAEQRNqilsqqlqq 300
Cdd:NF012221  1613 EESRAVTKELTTLAQGLDAldsqatyagESGDQWRNPFAGGLLDRVQEQLDDAKKIS---GKQLADAKQRH--------- 1680

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  301 iEAEHNTLRNTVetereeskillEKMELEVAErklSFHNLQEemrhlleqLEQAG-QAQAELESRYS-ALEQKHKAEMEE 378
Cdd:NF012221  1681 -VDNQQKVKDAV-----------AKSEAGVAQ---GEQNQAN--------AEQDIdDAKADAEKRKDdALAKQNEAQQAE 1737

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1622909128  379 KTSHILSlqktgQELQSAcdalKDQNSKLLQDKDEQAVQSAQTIEQLED 427
Cdd:NF012221  1738 SDANAAA-----NDAQSR----GEQDASAAENKANQAQADAKGAKQDES 1777
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2473-2759 6.90e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 6.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2473 NDRDRIVGDY-------QQLEErhlsvileKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdAELIQYREDLNQV 2545
Cdd:COG4913    593 DDRRRIRSRYvlgfdnrAKLAA--------LEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV 663

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2546 isikDSQQKQL--LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTAL 2623
Cdd:COG4913    664 ----ASAEREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 2624 QEEGTLGiYHAQLkvkeeELQRLSALLSSSQKRITE-LEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETET 2702
Cdd:COG4913    740 EDLARLE-LRALL-----EERFAAALGDAVERELREnLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLES 813

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622909128 2703 AEERVAELAR----DLVEMEQKLL-MVTKENKDLTAQIQsfgrsmSSLQNSRDHANEELDEL 2759
Cdd:COG4913    814 LPEYLALLDRleedGLPEYEERFKeLLNENSIEFVADLL------SKLRRAIREIKERIDPL 869
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 892-1599 7.26e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.41  E-value: 7.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  892 ETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEA----KKEQVEEDNEVVSGLKQNYDE 967
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAmadiRRRESQSQEDLRNQLQNTVHE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  968 MSPAGLISKeelqhefDLLKKENEQRKrKLQAALINRKELLQRVSRLeeeLANLKDQSKKEIplsesergeVEEDKENke 1047
Cdd:pfam15921  154 LEAAKCLKE-------DMLEDSNTQIE-QLRKMMLSHEGVLQEIRSI---LVDFEEASGKKI---------YEHDSMS-- 211

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1048 ysekcvTSKCQEIEISLKQTISEKEVELEHIRKDLeekMAAEEQLQALVKEMNQTLQDKTNQ-IDLLQAEISENQVIIQK 1126
Cdd:pfam15921  212 ------TMHFRSLGSAISKILRELDTEISYLKGRI---FPVEDQLEALKSESQNKIELLLQQhQDRIEQLISEHEVEITG 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1127 LTTSNTDASDgDSVALVKETVVISPPGTDSGEHWKPELEEkilaLEKEKEQLQKKLQEAltsrkaiLKKAQEKERHLREE 1206
Cdd:pfam15921  283 LTEKASSARS-QANSIQSQLEIIQEQARNQNSMYMRQLSD----LESTVSQLRSELREA-------KRMYEDKIEELEKQ 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1207 LKQQKDDYNRLQEQFDEQSKENENIGDQLRQL--QIQVRESIDGKLPSPDQQEWCSPTPGleeplfKATEQHHTQPVLES 1284
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESGNLDDQLQKLlaDLHKREKELSLEKEQNKRLWDRDTGN------SITIDHLRRELDDR 424

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1285 NLcpdWPSHSEDASALQGGTSVAQIKAQLKEIETEKEKLElKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHE 1364
Cdd:pfam15921  425 NM---EVQRLEALLKAMKSECQGQMERQMAAIQGKNESLE-KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSD 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1365 AEVRAESLQQKLESSQLQIAGLEHLRELQpeLDELQKLISEKEEdvsylsgqlrekeaaLTKIQTEIieqedlikalhTQ 1444
Cdd:pfam15921  501 LTASLQEKERAIEATNAEITKLRSRVDLK--LQELQHLKNEGDH---------------LRNVQTEC-----------EA 552

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1445 LEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEElslARDTIEHLTKSLAD 1524
Cdd:pfam15921  553 LKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDK---KDAKIRELEARVSD 629

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909128 1525 VE-SHVSAQNKEKDRvLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIE-SLKSSK 1599
Cdd:pfam15921  630 LElEKVKLVNAGSER-LRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKmQLKSAQ 705
46 PHA02562
endonuclease subunit; Provisional
 662-903 7.44e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 7.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  662 ELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILElelNFHKAQEIYEKNLdEKAK----EISNLNQLIEEFKKNADNN 737
Cdd:PHA02562   178 ELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGE---NIARKQNKYDELV-EEAKtikaEIEELTDELLNLVMDIEDP 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  738 SSAFTALSEERDQLLAQVKELSVVTELraqvrqlemnlaeaerqrrfdYESQ----TAHHNLLTEQIHSLSIEAKSKDV- 812
Cdd:PHA02562   254 SAALNKLNTAAAKIKSKIEQFQKVIKM---------------------YEKGgvcpTCTQQISEGPDRITKIKDKLKELq 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  813 ----KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQlllEKK 888
Cdd:PHA02562   313 hsleKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD---ELD 389

                          250
                   ....*....|....*
gi 1622909128  889 RDVETLQQTIEEKDQ 903
Cdd:PHA02562   390 KIVKTKSELVKEKYH 404
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 1310-1616 7.85e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 42.15  E-value: 7.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1310 KAQLKEIETEKEKLELKISSTTSELTKKSEEVfqLQDQINKQGLEIESLKTASheaeVRAESLQQKLESSQLQIAGL--- 1386
Cdd:PLN03229   428 KTPVRELEGEVEKLKEQILKAKESSSKPSELA--LNEMIEKLKKEIDLEYTEA----VIAMGLQERLENLREEFSKAnsq 501

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1387 EHLreLQPEL-DELQKLISEKEEDVS----YLSgqLREKEAALTKIQTEIIEQEDLIKALHTQLEMqakehDERIKQLqV 1461
Cdd:PLN03229   502 DQL--MHPVLmEKIEKLKDEFNKRLSrapnYLS--LKYKLDMLNEFSRAKALSEKKSKAEKLKAEI-----NKKFKEV-M 571

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1462 ELCEMKQKPEEIEEESrAKQQIQRKLQAALISRKEALKENKSLQEEL-----SLARDTIEHLTKSLADVESHVSAQNKEK 1536
Cdd:PLN03229   572 DRPEIKEKMEALKAEV-ASSGASSGDELDDDLKEKVEKMKKEIELELagvlkSMGLEVIGVTKKNKDTAEQTPPPNLQEK 650

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1537 drvlgrLALLQEERDKLITEMDRSllenQSLSGSCESLKL--ALEGLTEDKEkLVKEIESLKSS---KIAE---SSEWQE 1608
Cdd:PLN03229   651 ------IESLNEEINKKIERVIRS----SDLKSKIELLKLevAKASKTPDVT-EKEKIEALEQQikqKIAEalnSSELKE 719


                   ....*...
gi 1622909128 1609 KHKELQKE 1616
Cdd:PLN03229   720 KFEELEAE 727
PLN02939 PLN02939
transferase, transferring glycosyl groups
 628-995 9.04e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 41.81  E-value: 9.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  628 PNEESSLPAVEKEQASTEHQNRTSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDeleRLKSQILELelNFHKAQE 707
Cdd:PLN02939    40 RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHN---RASMQRDEA--IAAIDNE 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  708 IYEKNLDEKakEISNLNqlIEEFKKNADNNSSAFTALSEERDQLLAQV-KELSVVTELRAQVRQLEMNLAEAERQRRFDY 786
Cdd:PLN02939   115 QQTNSKDGE--QLSDFQ--LEDLVGMIQNAEKNILLLNQARLQALEDLeKILTEKEALQGKINILEMRLSETDARIKLAA 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  787 ESQtAHHNLLTEQI----HSLSIEAKSKDVKIEVLQNELDDVQlqfsEQSTLIRSLQSQLQNKESEVLEGAERV------ 856
Cdd:PLN02939   191 QEK-IHVEILEEQLeklrNELLIRGATEGLCVHSLSKELDVLK----EENMLLKDDIQFLKAELIEVAETEERVfkleke 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  857 -RHISSKVEELSQALSQKELEIAKMDQLLLEKKRD-VETLQQTIEEKDQQVTEISFSMT-----EKMVQLNEEKFSLGVE 929
Cdd:PLN02939   266 rSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEkVENLQDLLDRATNQVEKAALVLDqnqdlRDKVDKLEASLKEANV 345

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909128  930 IKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEmspagliSKEELQHEFDLLKKENEQRKR 995
Cdd:PLN02939   346 SKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQE-------SIKEFQDTLSKLKEESKKRSL 404
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1058-1248 9.22e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 9.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1058 QEIEISLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDG 1137
Cdd:COG4942     40 EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQ 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128 1138 DSVALV--KETVVISPPGTDSGEHWKPELEEKILALEKEKEQLQkKLQEALTSRKAILKKAQEKERHLREELKQQKDDYN 1215
Cdd:COG4942    120 PPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA-ALRAELEAERAELEALLAELEEERAALEALKAERQ 198

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1622909128 1216 RLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1248
Cdd:COG4942    199 KLLARLEKELAELAAELAELQQEAEELEALIAR 231
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
496-1023 9.90e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.56  E-value: 9.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  496 LEELKAENEKLSSQiTLLEAQNRIGEADREV-SEISIVDDANKRSSSTEESGQDVLEnTFSQKHKELSVLLLEMKEAQEE 574
Cdd:PRK02224   189 LDQLKAQIEEKEEK-DLHERLNGLESELAELdEEIERYEEQREQARETRDEADEVLE-EHEERREELETLEAEIEDLRET 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  575 IAFLKlqlqgKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDtgqnfplmpneeSSLPAVEKEQASTEHQNRTSEEi 654
Cdd:PRK02224   267 IAETE-----REREELAEEVRDLRERLEELEEERDDLLAEAGLDD------------ADAEAVEARREELEDRDEELRD- 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  655 SLNDAGVELKSTKQDCDKSLSAVPDigqcHQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNA 734
Cdd:PRK02224   329 RLEECRVAAQAHNEEAESLREDADD----LEERAEELREEAAELESELEEARE----AVEDRREEIEELEEEIEELRERF 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  735 DNNSSAFTALSEERDQLLAQVKEL-SVVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHnlLTEQIHSLSIEakSKDVK 813
Cdd:PRK02224   401 GDAPVDLGNAEDFLEELREERDELrEREAELEATLRTARERVEEAEALLEAGKCPECGQP--VEGSPHVETIE--EDRER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  814 IEVLQNELDDVQLQFS------EQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEK 887
Cdd:PRK02224   477 VEELEAELEDLEEEVEeveerlERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909128  888 KRDVETLQQTIEEKDQQVTEISFSMTE---------KMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVV 958
Cdd:PRK02224   557 REAAAEAEEEAEEAREEVAELNSKLAElkeriesleRIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERK 636

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909128  959 SGLKQNYDEMspagliSKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKD 1023
Cdd:PRK02224   637 RELEAEFDEA------RIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEE 695
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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