|
Name |
Accession |
Description |
Interval |
E-value |
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
94-776 |
0e+00 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 901.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 94 LAERASRSIHQLKCALKEGDVTIGGDAPNLSFSTSVGNEDARTAWPELQQSHAVNQLKDLLRRQADKESEVSPSRRKMSP 173
Cdd:pfam15964 16 LRERANRSIHQLKCALHESDSTISEDEQEESLSSVVQNEDSGSPWSELQHSHAVNQLKALLQQQTKKENELSPRRRKLSP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 174 LRSLEHEETNMPTMHNLVPIINDQSQYIHHLEAEVKFCKEELSGLKNKIQAVVLENESLQQELKSQRQEETLREQTLLDA 253
Cdd:pfam15964 96 SRTSEDESSSLPTVHDLVPIINDQSQYIHHLEAEVKFCKEELSEMKQRVQVVVLENEKLQQELKSQTQEETLREQTLLDS 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 254 SGNVQNSWITtGEDSGVGEAAKRPFSHDNADIGKAASAGE----QLELEKLKLTYEEKYEIQESQLKFLRKDLAEYQRTC 329
Cdd:pfam15964 176 SGNMQNSWCT-PEDSRVHQTSKRPASHNLAERLKSATTGEdekwRLELEKLKLLYEAKTEVLESQVKSLRKDLAESQKTC 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 330 EDLKEQLKHKEFLLAANTSNRVAGLCLKCAQHEAVLSQTHNNVHMQTIERLMKERDDLMSALVSVRSSLADTQQREASAY 409
Cdd:pfam15964 255 EDLKERLKHKESLVAASTSSRVGGLCLKCAQHEAVLAQTHTNVHMQTIERLTKERDDLMSALVSVRSSLAEAQQRESSAY 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 410 EQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKRAIEKDMMKKEITKERESMGSKMLILSQNIAQ 489
Cdd:pfam15964 335 EQVKQAVQMTEEANFEKTKALIQCEQLKSELERQKERLEKELASQQEKRAQEKEALRKEMKKEREELGATMLALSQNVAQ 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 490 LEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKANMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLR 569
Cdd:pfam15964 415 LEAQVEKVTREKNSLVSQLEEAQKQLASQEMDVTKVCGEMRYQLNQTKMKKDEAEKEHREYRTKTGRQLEIKDQEIEKLG 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 570 IELGESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQ 649
Cdd:pfam15964 495 LELSESKQRLEQAQQDAARAREECLKLTELLGESEHQLHLTRLEKESIQQSFSNEAKAQALQAQQREQELTQKMQQMEAQ 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 650 HDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHE 729
Cdd:pfam15964 575 HDKTVNEQYSLLTSQNTFIAKLKEECCTLAKKLEEITQKSRSEVEQLSQEKEYLQDRLEKLQKRNEELEEQCVQHGRMHE 654
|
650 660 670 680
....*....|....*....|....*....|....*....|....*..
gi 966924188 730 IMKQRLRQLDKHSQATAQQLVQLLNKQNQLLLERQSLSEEVDRLRTQ 776
Cdd:pfam15964 655 RMKQRLRQLDKHCQATAQQLVQLLSKQNQLFKERQNLTEEVQSLRSQ 701
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
436-749 |
2.83e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 73.82 E-value: 2.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 436 LRKELERQAERLEKElASQQEK-RAIEKDMMKKEItkerESMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQ 514
Cdd:COG1196 194 ILGELERQLEPLERQ-AEKAERyRELKEELKELEA----ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAE 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 515 LASREMDVTkvcgEMRYQLNKANMEKDEAEKEHREFRAKTNRDLEIK---DQEIEKLRIELGESKQHLEQEQQKAARARE 591
Cdd:COG1196 269 LEELRLELE----ELELELEEAQAEEYELLAELARLEQDIARLEERRrelEERLEELEEELAELEEELEELEEELEELEE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 592 ECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTsqntfLTKL 671
Cdd:COG1196 345 ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER-----LERL 419
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966924188 672 KEECCTLAKKLEQISQKTRSEIAQLSQEKRytydKLGKLQRRNEELEEQCVQHGRVHEIMKQRLRQLDKHSQATAQQL 749
Cdd:COG1196 420 EEELEELEEALAELEEEEEEEEEALEEAAE----EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
469-738 |
1.03e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.46 E-value: 1.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 469 ITKERESMGSKMLILSQNIAQLEAQVEKVT---KEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKANMEKDEAEK 545
Cdd:TIGR02168 661 ITGGSAKTNSSILERRREIEELEEKIEELEekiAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 546 EHREFRAKTNR----------DLEIKDQEIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTRQEKD 615
Cdd:TIGR02168 741 EVEQLEERIAQlskelteleaEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAA 820
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 616 SiQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEqyllLTSQNTFLTKLKEECCTLAKKLEQISQ---KTRSE 692
Cdd:TIGR02168 821 N-LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE----IEELEELIEELESELEALLNERASLEEalaLLRSE 895
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 966924188 693 IAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHEIMKQRLRQL 738
Cdd:TIGR02168 896 LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
312-638 |
2.82e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.19 E-value: 2.82e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 312 ESQLKFLRKD---LAEYQrtceDLKEQLKHKEFLLAANTsnrvaglcLKCAQHEAVLSQTHNNVHMQTIERLMKERDDLM 388
Cdd:COG1196 199 ERQLEPLERQaekAERYR----ELKEELKELEAELLLLK--------LRELEAELEELEAELEELEAELEELEAELAELE 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 389 SALVSVRSSLADTQQREASAyeQVKQVLQISEEANFEKTKALIQcdQLRKELERQAERLEKELAsQQEKRAIEKDMMKKE 468
Cdd:COG1196 267 AELEELRLELEELELELEEA--QAEEYELLAELARLEQDIARLE--ERRRELEERLEELEEELA-ELEEELEELEEELEE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 469 ITKERESMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDvtkvcgemRYQLNKANMEKDEAEKEHR 548
Cdd:COG1196 342 LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA--------AAELAAQLEELEEAEEALL 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 549 EFRAKTNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQ 628
Cdd:COG1196 414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493
|
330
....*....|
gi 966924188 629 ALQAQQREQE 638
Cdd:COG1196 494 LLLLEAEADY 503
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
377-657 |
1.23e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.88 E-value: 1.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 377 IERLMKERDDLMSALVSVRSSLADTQQREASAYEQVKQvlqisEEANFEKTKALIQCDQLRKELERQAERLEKELASQQE 456
Cdd:COG1196 227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAE-----LEAELEELRLELEELELELEEAQAEEYELLAELARLE 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 457 KRAIEKDMMKKEITKERESmgskmliLSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREmdvtkvcgEMRYQLNKA 536
Cdd:COG1196 302 QDIARLEERRRELEERLEE-------LEEELAELEEELEELEEELEELEEELEEAEEELEEAE--------AELAEAEEA 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 537 NMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTRQEKDS 616
Cdd:COG1196 367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 966924188 617 IQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQ 657
Cdd:COG1196 447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
410-727 |
5.80e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.69 E-value: 5.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 410 EQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELAsQQEKRAIEKDMMKKEITKERESMGSKMLILSQNIAQ 489
Cdd:TIGR02168 680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE-ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 490 LEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEM---RYQLNKANMEKDEaekEHREFRAKTNRdLEIKDQEIE 566
Cdd:TIGR02168 759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELkalREALDELRAELTL---LNEEAANLRER-LESLERRIA 834
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 567 KLRIELGESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTRQEKDSIQQsfskeakaQALQAQQREQELTQKIQQM 646
Cdd:TIGR02168 835 ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEE--------ALALLRSELEELSEELREL 906
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 647 EAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGR 726
Cdd:TIGR02168 907 ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP 986
|
.
gi 966924188 727 V 727
Cdd:TIGR02168 987 V 987
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
438-720 |
9.47e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 59.31 E-value: 9.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 438 KELERQAERLEKELASQQEKraiekdmmKKEITKERESMGSKMLILSQNIAQLEAQVEKVTKEKISAIN-QLEEIQSQLA 516
Cdd:TIGR02169 233 EALERQKEAIERQLASLEEE--------LEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKeKIGELEAEIA 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 517 SREMDVTKVCGEMR---YQLNKANMEKDEAEKEHREFRAKTNRDLEIKDQ---EIEKLRIELGESKQHLEQEQQKAARAR 590
Cdd:TIGR02169 305 SLERSIAEKERELEdaeERLAKLEAEIDKLLAEIEELEREIEEERKRRDKlteEYAELKEELEDLRAELEEVDKEFAETR 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 591 EEclrltelLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREqELTQKIQQMEAQHDKTENEqyllltsqntfLTK 670
Cdd:TIGR02169 385 DE-------LKDYREKLEKLKREINELKRELDRLQEELQRLSEELA-DLNAAIAGIEAKINELEEE-----------KED 445
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 966924188 671 LKEECCTLAKKLEQISQ---KTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQ 720
Cdd:TIGR02169 446 KALEIKKQEWKLEQLAAdlsKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
430-749 |
1.01e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.91 E-value: 1.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 430 LIQCDQLRKELERQAERLEKelasqQEKRAIEkdmmKKEITKERESMgsKMLILSQNIAQLEAQVEKVTKEKISAINQLE 509
Cdd:TIGR02168 188 LDRLEDILNELERQLKSLER-----QAEKAER----YKELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 510 EIQSQLASREMDVTkvcgEMRYQLNKANMEKDEAEKEHREFRAKTNRdleiKDQEIEKLRIELGESKQHLEQEQQKAARA 589
Cdd:TIGR02168 257 ELTAELQELEEKLE----ELRLEVSELEEEIEELQKELYALANEISR----LEQQKQILRERLANLERQLEELEAQLEEL 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 590 REECLRLTELLGESEHQLHLTRQEKDSIQQSFsKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLltsqNTFLT 669
Cdd:TIGR02168 329 ESKLDELAEELAELEEKLEELKEELESLEAEL-EELEAELEELESRLEELEEQLETLRSKVAQLELQIASL----NNEIE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 670 KLKEECCTLAKKLEQISQKTRSEIAQLS-QEKRYTYDKLGKLQRRNEELEEQCVQHGRVHEIMKQRLRQLDKHSQATAQQ 748
Cdd:TIGR02168 404 RLEARLERLEDRRERLQQEIEELLKKLEeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE 483
|
.
gi 966924188 749 L 749
Cdd:TIGR02168 484 L 484
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
375-656 |
3.38e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 3.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 375 QTIERLMKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEeanfektKALIQCDQLRKELERQAERLEkELASQ 454
Cdd:TIGR02168 698 KALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE-------QLEERIAQLSKELTELEAEIE-ELEER 769
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 455 QEKRAIEKDMMKKEITKERESMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREM------DVTKVCGE 528
Cdd:TIGR02168 770 LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAterrleDLEEQIEE 849
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 529 MRYQLNKANMEKDEAEKEHREFRAKTNRDLEIKD---QEIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGESEH 605
Cdd:TIGR02168 850 LSEDIESLAAEIEELEELIEELESELEALLNERAsleEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL 929
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 966924188 606 QLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENE 656
Cdd:TIGR02168 930 RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
483-776 |
2.04e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.56 E-value: 2.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 483 LSQNIAQLEAQVEKVTK-EKISAinQLEEIQSQLASREMDvtkvcgEMRYQLNKANMEKDEAEKEHREFRAktnrdleik 561
Cdd:COG1196 198 LERQLEPLERQAEKAERyRELKE--ELKELEAELLLLKLR------ELEAELEELEAELEELEAELEELEA--------- 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 562 dqEIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTRQEKDSIQQsfskeakaqalqaqqREQELTQ 641
Cdd:COG1196 261 --ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE---------------RLEELEE 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 642 KIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRyTYDKLGKLQRRNEELEEQC 721
Cdd:COG1196 324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE-LAEELLEALRAAAELAAQL 402
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 966924188 722 VQHGRVHEIMKQRLRQLDKHSQATAQQLVQLLNKQNQLLLERQSLSEEVDRLRTQ 776
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
140-776 |
7.35e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.14 E-value: 7.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 140 ELQQSHAVNQLKDLLRRQADKESEVSPSRRKMSPLRSLEHEETNmptmhnlvpIINDQSQYIHHLEAEVKFCKEELSGLK 219
Cdd:TIGR02168 245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK---------ELYALANEISRLEQQKQILRERLANLE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 220 NKIQAVVLENESLQQELKSQRQEETLREQTLLDASGNVQNSWITTGEDSGVGEAAKRPFSHDNADIGKAASAGEQLELEK 299
Cdd:TIGR02168 316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 300 LKLTyeekyeiqeSQLKFLRKDLAEYQRTCEDLKEQlkhKEFLLAANTSNRVAGLCLKCAQHEAVLS--QTHNNVHMQTI 377
Cdd:TIGR02168 396 ASLN---------NEIERLEARLERLEDRRERLQQE---IEELLKKLEEAELKELQAELEELEEELEelQEELERLEEAL 463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 378 ERLMKERDDLMSALVSVRS----------SLADTQQREASAYEQVKQVLQ---------------ISEEANFEKTKALIQ 432
Cdd:TIGR02168 464 EELREELEEAEQALDAAERelaqlqarldSLERLQENLEGFSEGVKALLKnqsglsgilgvlselISVDEGYEAAIEAAL 543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 433 CDQLRKELERQAERLEKELASQQEKRAIEKDMMKKEITKERESMGSKMLILSQNIAQLEAQVEKVTKEK----------- 501
Cdd:TIGR02168 544 GGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllg 623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 502 ----ISAINQLEEIQSQLASREMDVTKvcgemryqlnkanmekdEAEKEHREF-----RAKTNRDLEIKDQEIEKLRIEL 572
Cdd:TIGR02168 624 gvlvVDDLDNALELAKKLRPGYRIVTL-----------------DGDLVRPGGvitggSAKTNSSILERRREIEELEEKI 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 573 GESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQ---ELTQKIQQMEAQ 649
Cdd:TIGR02168 687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQlskELTELEAEIEEL 766
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 650 HDKTENEQYLLLTsqntfltkLKEECCTLAKKLEQIS---QKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGR 726
Cdd:TIGR02168 767 EERLEEAEEELAE--------AEAEIEELEAQIEQLKeelKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|
gi 966924188 727 VHEIMKQRLRQLDKHSQATAQQLVQLLNKQNQLLLERQSLSEEVDRLRTQ 776
Cdd:TIGR02168 839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA 888
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
375-719 |
9.15e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.76 E-value: 9.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 375 QTIERLMKERDDLMsalvsvRSSLADTQQREASAYEQVKQVlqisEEANFEKTKALIQCDQLRKELE---RQAERLEKEL 451
Cdd:TIGR02169 198 QQLERLRREREKAE------RYQALLKEKREYEGYELLKEK----EALERQKEAIERQLASLEEELEkltEEISELEKRL 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 452 ASQQEKRaiekdmmkKEITKERESMGS-KMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMR 530
Cdd:TIGR02169 268 EEIEQLL--------EELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIE 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 531 yqlnkaNMEKDEAEKehrefraktNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAARAREEclrltelLGESEHQLHLT 610
Cdd:TIGR02169 340 ------ELEREIEEE---------RKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE-------LKDYREKLEKL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 611 RQEKDSIQQSFSKeakaqalqAQQREQELTQKIQQMEAQHDKTENEqyllltsqntfLTKLKEECCTLAKKLEQISQKTR 690
Cdd:TIGR02169 398 KREINELKRELDR--------LQEELQRLSEELADLNAAIAGIEAK-----------INELEEEKEDKALEIKKQEWKLE 458
|
330 340
....*....|....*....|....*....
gi 966924188 691 SEIAQLSQEKRYTYDKLGKLQRRNEELEE 719
Cdd:TIGR02169 459 QLAADLSKYEQELYDLKEEYDRVEKELSK 487
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
405-737 |
3.05e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 51.13 E-value: 3.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 405 EASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKelasqQEKRAIEKDMMKKEITKERESMG-SKMLIL 483
Cdd:pfam02463 160 EEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKE-----QAKKALEYYQLKEKLELEEEYLLyLDYLKL 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 484 SQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKANMEKDEAEKEHREFRAKTNRDLEIKDQ 563
Cdd:pfam02463 235 NEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEE 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 564 EIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTRQE-------KDSIQQSFSKEAKAQALQAQQRE 636
Cdd:pfam02463 315 KLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLqekleqlEEELLAKKKLESERLSSAAKLKE 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 637 QELTQKIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEE 716
Cdd:pfam02463 395 EELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474
|
330 340
....*....|....*....|.
gi 966924188 717 LEEQCVQHGRVHEIMKQRLRQ 737
Cdd:pfam02463 475 KETQLVKLQEQLELLLSRQKL 495
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
395-669 |
6.32e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.06 E-value: 6.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 395 RSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEK-----RAIEKDMMKKEI 469
Cdd:TIGR02168 227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKElyalaNEISRLEQQKQI 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 470 TKERESMgskmliLSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASremdVTKVCGEMRYQLNKANMEK-------DE 542
Cdd:TIGR02168 307 LRERLAN------LERQLEELEAQLEELESKLDELAEELAELEEKLEE----LKEELESLEAELEELEAELeelesrlEE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 543 AEKEHREFRAKTNRdleiKDQEIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGESE-----HQLHLTRQEKDSI 617
Cdd:TIGR02168 377 LEEQLETLRSKVAQ----LELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelqAELEELEEELEEL 452
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 966924188 618 QQSFSkEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNTFLT 669
Cdd:TIGR02168 453 QEELE-RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
221-749 |
6.78e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.14 E-value: 6.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 221 KIQAVVLENESLQQELKSQRQEE-----TLREQTLLDASGNVQNSWITTGEDSGVGEAAKRPFSHDNADigKAASAGEQL 295
Cdd:PTZ00121 1225 KAEAVKKAEEAKKDAEEAKKAEEernneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD--EAKKAEEKK 1302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 296 ELEKLKLTYEEKYEIQEsqlkfLRKDLAEYQRTCEDLKEQLKHKEfllaanTSNRVAGLCLKCAQHEAVLSQTHNNVHMQ 375
Cdd:PTZ00121 1303 KADEAKKKAEEAKKADE-----AKKKAEEAKKKADAAKKKAEEAK------KAAEAAKAEAEAAADEAEAAEEKAEAAEK 1371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 376 TIERLMKERDDLMSALVSVRSS--LADTQQREASAYEQVKQVLQISEEANFEKTKA--LIQCDQLRKELE--RQAERL-- 447
Cdd:PTZ00121 1372 KKEEAKKKADAAKKKAEEKKKAdeAKKKAEEDKKKADELKKAAAAKKKADEAKKKAeeKKKADEAKKKAEeaKKADEAkk 1451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 448 ---EKELASQQEKRAIEK---DMMKKEITKERESMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMD 521
Cdd:PTZ00121 1452 kaeEAKKAEEAKKKAEEAkkaDEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 522 VTKVCGEMRY--------------QLNKAN-MEKDEAEKEHREFRAKTNRDLEIKDQeIEKLRIElGESKQHLEQEQQKA 586
Cdd:PTZ00121 1532 EAKKADEAKKaeekkkadelkkaeELKKAEeKKKAEEAKKAEEDKNMALRKAEEAKK-AEEARIE-EVMKLYEEEKKMKA 1609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 587 ARAREEclrltELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNT 666
Cdd:PTZ00121 1610 EEAKKA-----EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 667 FLTKLKEECCTL----AKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQ--RRNEELEEQCVQHGRVHEIMKQRLRQLDK 740
Cdd:PTZ00121 1685 EDEKKAAEALKKeaeeAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEeaKKEAEEDKKKAEEAKKDEEEKKKIAHLKK 1764
|
....*....
gi 966924188 741 HSQATAQQL 749
Cdd:PTZ00121 1765 EEEKKAEEI 1773
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
394-549 |
7.15e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 49.39 E-value: 7.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 394 VRSSLADTQQREASayEQVKQVLQISE-EANFEKTKALIQC----DQLRKELERQAERLEKELAsQQEKRAIEK----DM 464
Cdd:PRK12704 24 VRKKIAEAKIKEAE--EEAKRILEEAKkEAEAIKKEALLEAkeeiHKLRNEFEKELRERRNELQ-KLEKRLLQKeenlDR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 465 MKKEITKERESMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIqSQLAS---REMDVTKVCGEMRYQ----LNKAN 537
Cdd:PRK12704 101 KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERI-SGLTAeeaKEILLEKVEEEARHEaavlIKEIE 179
|
170
....*....|...
gi 966924188 538 ME-KDEAEKEHRE 549
Cdd:PRK12704 180 EEaKEEADKKAKE 192
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
483-774 |
8.74e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 49.67 E-value: 8.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 483 LSQNIAQLEAQVEKVTKEKisAI-NQLEEIQSQLASREMDvtkvcgEMRYQLNKANMEKDEAEKEHREfrakTNRDLEIK 561
Cdd:TIGR02168 198 LERQLKSLERQAEKAERYK--ELkAELRELELALLVLRLE------ELREELEELQEELKEAEEELEE----LTAELQEL 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 562 DQEIEKLRIELGESKQHLEQEQQkaarareECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQRE----- 636
Cdd:TIGR02168 266 EEKLEELRLEVSELEEEIEELQK-------ELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDelaee 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 637 --------QELTQKIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQkTRSEIAQLSQEKRYTYDKLG 708
Cdd:TIGR02168 339 laeleeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS-LNNEIERLEARLERLEDRRE 417
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966924188 709 KLQRRNEELEEQCV------QHGRVHEImKQRLRQLDKHSQATAQQLVQLLNKQNQLLLERQSLSEEVDRLR 774
Cdd:TIGR02168 418 RLQQEIEELLKKLEeaelkeLQAELEEL-EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
375-592 |
1.46e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 1.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 375 QTIERLMKERDDLMSALVSVRSSLADTQQREASAYEQVKQVlqisEEANFEKTKALIQCDQLRKELERQAERLEKELASQ 454
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL----ERRIAALARRIRALEQELAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 455 QEKRAIEKDMMKKEItKERESMGS----KMLILSQNIAQLEAQ---VEKVTKEKISAINQLEEIQSQLASREMDVTKVCG 527
Cdd:COG4942 96 RAELEAQKEELAELL-RALYRLGRqpplALLLSPEDFLDAVRRlqyLKYLAPARREQAEELRADLAELAALRAELEAERA 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966924188 528 EMRYQLNKANMEKDE---AEKEHREFRAKTNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAARAREE 592
Cdd:COG4942 175 ELEALLAELEEERAAleaLKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
435-649 |
2.06e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.45 E-value: 2.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 435 QLRKELERQAERLEKELASQQEKRAIEKDMmKKEITKERESMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQ 514
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKE-EKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 515 LASREMDVTKVCGEMrYQLNKANMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAARAREECL 594
Cdd:COG4942 99 LEAQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 966924188 595 RLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQA---LQAQQREQELTQKIQQMEAQ 649
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLARLEKELAELAaelAELQQEAEELEALIARLEAE 235
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
484-720 |
2.13e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.45 E-value: 2.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 484 SQNIAQLEAQVEKVTKEkisaINQLEEIQSQLASREMDVTKVCGEMRYQLNKANMEKDEAEKEhrefRAKTNRDLEIKDQ 563
Cdd:COG4942 19 ADAAAEAEAELEQLQQE----IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE----LAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 564 EIEKLRIELGESKQHLeQEQQKAARAREECLRLTELLGESEHQLHLTRQEkdsIQQSFSKEAKAQALQAQQREQELTQKI 643
Cdd:COG4942 91 EIAELRAELEAQKEEL-AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQ---YLKYLAPARREQAEELRADLAELAALR 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966924188 644 QQMEAQHDKTEnEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQ 720
Cdd:COG4942 167 AELEAERAELE-ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
401-774 |
4.14e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 47.27 E-value: 4.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 401 TQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKEL------ERQAERLEKELASQQEKRAIEKDMMK-KEITKER 473
Cdd:TIGR00618 223 VLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLkqlrarIEELRAQEAVLEETQERINRARKAAPlAAHIKAV 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 474 ESMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASrEMDVTKVCGEMRYQLNKANMEKDEAEKEHREfrak 553
Cdd:TIGR00618 303 TQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRL-LQTLHSQEIHIRDAHEVATSIREISCQQHTL---- 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 554 tNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAARAreeclrLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQ 633
Cdd:TIGR00618 378 -TQHIHTLQQQKTTLTQKLQSLCKELDILQREQATI------DTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCT 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 634 QREQELTQKIQQMEAQHDKTENEQyllLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQ--EKRYTYDKLGKLQ 711
Cdd:TIGR00618 451 AQCEKLEKIHLQESAQSLKEREQQ---LQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHpnPARQDIDNPGPLT 527
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966924188 712 RRNEELEEQCVQHGRVHEIMKQRLRQLDKHSQATAQQLVQLLNKQNQLLLERQSLSEEVDRLR 774
Cdd:TIGR00618 528 RRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQ 590
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
396-619 |
4.54e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 46.81 E-value: 4.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 396 SSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKraIEKDMMK-KEITKERE 474
Cdd:pfam07888 34 NRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREK--HEELEEKyKELSASSE 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 475 SMGSKMLILSQNIAQLEAQvekvtkekisaINQLEEIQSQLASREMDVTKVCGEMRYQLNKANMEKDEAEKEHREFRAKt 554
Cdd:pfam07888 112 ELSEEKDALLAQRAAHEAR-----------IRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAK- 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966924188 555 nrdLEIKDQEIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGES---EHQLHLTRQEKDSIQQ 619
Cdd:pfam07888 180 ---LQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAhrkEAENEALLEELRSLQE 244
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
535-773 |
8.96e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.21 E-value: 8.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 535 KANMEKDEAEKEHREFRAKtnrdLEIKDQEIEKLRIElgeskqHLEQEQQKAARAREECLRLTELLGE---SEHQLHLTR 611
Cdd:TIGR02169 174 KALEELEEVEENIERLDLI----IDEKRQQLERLRRE------REKAERYQALLKEKREYEGYELLKEkeaLERQKEAIE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 612 QEKDSIQQSFSKeAKAQALQAQQREQELTQKIQQMEAQ-HDKTENEQYLL------LTSQNTFLTKLKEECCTLAKKLEQ 684
Cdd:TIGR02169 244 RQLASLEEELEK-LTEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVkekigeLEAEIASLERSIAEKERELEDAEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 685 ISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHEIMKQRLRQLDKHSQATAQQLVQLLNKQNQLLLERQ 764
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN 402
|
....*....
gi 966924188 765 SLSEEVDRL 773
Cdd:TIGR02169 403 ELKRELDRL 411
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
293-776 |
9.17e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 46.08 E-value: 9.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 293 EQLELEKLKLTYEEKYEIQESQLKFLRKDLAEYQRTCEDLKEQLKHKEFLLAANTSNRVAglclkcAQHEAVLSQTHNNV 372
Cdd:COG1196 261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE------LEEELAELEEELEE 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 373 HMQTIERLMKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELA 452
Cdd:COG1196 335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 453 SQQEKRAIEKDMMKKEITKERESMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQ 532
Cdd:COG1196 415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 533 LnKANMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLR-----------IELGESKQHLEQEQQKAARAREECL------R 595
Cdd:COG1196 495 L-LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaayeaaleAALAAALQNIVVEDDEVAAAAIEYLkaakagR 573
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 596 LTELLGESEHQLHLTRQEKDSIQQSF----------SKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQN 665
Cdd:COG1196 574 ATFLPLDKIRARAALAAALARGAIGAavdlvasdlrEADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEG 653
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 666 T-----------FLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHEIMKQR 734
Cdd:COG1196 654 EggsaggsltggSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 966924188 735 LRQLDKHSQATAQQLVQLLNKQNQLLLERQSLSEEVDRLRTQ 776
Cdd:COG1196 734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
435-749 |
1.11e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.83 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 435 QLRKELERQAER---LEKELAS-QQEKRAIEKDMmkKEITKERESMGSKMLILSQNIAQLEAQVEKVTKEkisainqLEE 510
Cdd:TIGR02169 671 SEPAELQRLRERlegLKRELSSlQSELRRIENRL--DELSQELSDASRKIGEIEKEIEQLEQEEEKLKER-------LEE 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 511 IQSQLASREMDVTKVcgemryqlnKANMEKDEAEKEHREfraktnRDLEIKDQEIEKLRIELGESKqhLEQEQQKAARAR 590
Cdd:TIGR02169 742 LEEDLSSLEQEIENV---------KSELKELEARIEELE------EDLHKLEEALNDLEARLSHSR--IPEIQAELSKLE 804
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 591 EECLRLTELLGESEHQLHLTRQEKDSIQQSfskeakaqalqaqqrEQELTQKIQQMEAQHDKTENEQYLLltsqNTFLTK 670
Cdd:TIGR02169 805 EEVSRIEARLREIEQKLNRLTLEKEYLEKE---------------IQELQEQRIDLKEQIKSIEKEIENL----NGKKEE 865
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966924188 671 LKEECCTLAKKLEQIsqktRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCvqhgrvhEIMKQRLRQLDKHSQATAQQL 749
Cdd:TIGR02169 866 LEEELEELEAALRDL----ESRLGDLKKERDELEAQLRELERKIEELEAQI-------EKKRKRLSELKAKLEALEEEL 933
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
340-619 |
1.53e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 45.60 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 340 EFLLAANTSNRVAGLCLKcaqheavLSQTHNNV--HMQTIERLMKERDDLMSALVSVRSSLADtqqreasayeqvkQVLQ 417
Cdd:pfam12128 242 EFTKLQQEFNTLESAELR-------LSHLHFGYksDETLIASRQEERQETSAELNQLLRTLDD-------------QWKE 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 418 ISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKRAIEKDMMK------KEITKERESMGSKMLILSQNIAQLE 491
Cdd:pfam12128 302 KRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPswqselENLEERLKALTGKHQDVTAKYNRRR 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 492 AQVEKVTKEKISAIN-----QLEEIQSQLASREMDVTKVCGEMRYQLNKANMEKDEAEKEHRE-------------FRAK 553
Cdd:pfam12128 382 SKIKEQNNRDIAGIKdklakIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSrlgelklrlnqatATPE 461
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966924188 554 TNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTRQEKDSIQQ 619
Cdd:pfam12128 462 LLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELEL 527
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
563-776 |
2.65e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 2.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 563 QEIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQK 642
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 643 IQQMEAQHDKTENEQYLLLTSQNTFLTKLKeecctLAKKLEQISQKTRSEIAQLSQEKRytydklgKLQRRNEELEEQCV 722
Cdd:COG4942 107 AELLRALYRLGRQPPLALLLSPEDFLDAVR-----RLQYLKYLAPARREQAEELRADLA-------ELAALRAELEAERA 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 966924188 723 QHGRVHEIMKQRLRQLDKHSQATAQQLVQLLNKQNQLLLERQSLSEEVDRLRTQ 776
Cdd:COG4942 175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
402-720 |
2.69e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 44.63 E-value: 2.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 402 QQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELA-SQQEKRAIEKDMMKKE-----ITKERES 475
Cdd:TIGR04523 302 NQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTnSESENSEKQRELEEKQneiekLKKENQS 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 476 MGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKvcgeMRYQLNKANMEKDEAEKEHREFR---A 552
Cdd:TIGR04523 382 YKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIER----LKETIIKNNSEIKDLTNQDSVKEliiK 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 553 KTNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTRQEKDSI---QQSFSKEAKAQA 629
Cdd:TIGR04523 458 NLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLkekIEKLESEKKEKE 537
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 630 LQAQQREQELTQKIQQMEAQHDKTE----NEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYD 705
Cdd:TIGR04523 538 SKISDLEDELNKDDFELKKENLEKEidekNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEK 617
|
330
....*....|....*
gi 966924188 706 KLGKLQRRNEELEEQ 720
Cdd:TIGR04523 618 ELEKAKKENEKLSSI 632
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
201-648 |
4.58e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.77 E-value: 4.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 201 IHHLEAEVKFCKEELSGLKNKIQAVVLENESLQQELKSQRQEETLREQTLLDASGNVQNSWITTGEDSGVGEAAKrpfsh 280
Cdd:COG1196 325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA----- 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 281 dnADIGKAASAGEQLELEKLKLTyEEKYEIQESQLKFLRKDLAEYQRTCEDLKEQLKHKEFLLAANTSNRVAGLCLKCAQ 360
Cdd:COG1196 400 --AQLEELEEAEEALLERLERLE-EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 361 HEAVLSQTHNNVHMQTIERLMKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEkTKALIQCDQLRKEL 440
Cdd:COG1196 477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE-AALAAALQNIVVED 555
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 441 ERQAERLEKELASQQEKRA--IEKDMMKKEITKERESMGSKMLILSQNIAQLEAQVEKVTK-------EKISAINQLEEI 511
Cdd:COG1196 556 DEVAAAAIEYLKAAKAGRAtfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYvlgdtllGRTLVAARLEAA 635
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 512 QSQLASREMDVTKVCGEMRyQLNKANMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAARARE 591
Cdd:COG1196 636 LRRAVTLAGRLREVTLEGE-GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966924188 592 ECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQRE----------QELTQKIQQMEA 648
Cdd:COG1196 715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpdleelerelERLEREIEALGP 781
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
492-776 |
5.92e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.51 E-value: 5.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 492 AQVEKVTKEKISAINQLEEIQSQLASremdVTKVCGEMRYQLNKANMEKDEAEKehreFRAKTNrdlEIKDQEIEKLRIE 571
Cdd:TIGR02168 165 AGISKYKERRKETERKLERTRENLDR----LEDILNELERQLKSLERQAEKAER----YKELKA---ELRELELALLVLR 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 572 LGESKQHLEQEQQKAARAREECLRLTELLGESEHQLHLTR---QEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEA 648
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlevSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 649 QHDKTENEQYLLLTSQNTfLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRytydKLGKLQRRNEELEEQcvqhgrvH 728
Cdd:TIGR02168 314 LERQLEELEAQLEELESK-LDELAEELAELEEKLEELKEELESLEAELEELEA----ELEELESRLEELEEQ-------L 381
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 966924188 729 EIMKQRLRQLDKHSQATAQQLVQLLNKQNQLLLERQSLSEEVDRLRTQ 776
Cdd:TIGR02168 382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK 429
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
389-587 |
9.98e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.12 E-value: 9.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 389 SALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKRAIEKDMMKKE 468
Cdd:COG3883 16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 469 ITKERESMGSKMLILSQNIAQLEAQ---VEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKANMEKDEAEK 545
Cdd:COG3883 96 YRSGGSVSYLDVLLGSESFSDFLDRlsaLSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEA 175
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 966924188 546 EHREFRAKTNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAA 587
Cdd:COG3883 176 QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
412-718 |
1.00e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 42.74 E-value: 1.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 412 VKQVLQISEEANFEKTKAliqcdQLRKELERQAERLEKELAS---------QQEKRAIEKDMMKKEITKERESMGSKMLI 482
Cdd:PRK03918 151 VRQILGLDDYENAYKNLG-----EVIKEIKRRIERLEKFIKRtenieelikEKEKELEEVLREINEISSELPELREELEK 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 483 LSQNIAQLEAQVEKVT--KEKISAINQ----LEEIQSQLASREMDVTKVCGEMRYQLNKANMEKDEAEK--EHREFRAKT 554
Cdd:PRK03918 226 LEKEVKELEELKEEIEelEKELESLEGskrkLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyiKLSEFYEEY 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 555 NRDLEIKDQEIEKLRIELGESKQHLEQEQQKAARARE------ECLRLTELLGESEHQLHLTRQEKDSIQQSFSK----- 623
Cdd:PRK03918 306 LDELREIEKRLSRLEEEINGIEERIKELEEKEERLEElkkklkELEKRLEELEERHELYEEAKAKKEELERLKKRltglt 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 624 --EAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNTfLTKLKEECCTLAKKL-----EQISQKTRSEIAQL 696
Cdd:PRK03918 386 peKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-LKKAKGKCPVCGRELteehrKELLEEYTAELKRI 464
|
330 340
....*....|....*....|..
gi 966924188 697 SQEKRYTYDKLGKLQRRNEELE 718
Cdd:PRK03918 465 EKELKEIEEKERKLRKELRELE 486
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
312-524 |
1.00e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 1.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 312 ESQLKFLRKDLAEYQRTCEDLKEqlkhkefllaantsnrvaglclkcaQHEAVLSQTHNNVHMQTIERLMKERDDLMSAL 391
Cdd:COG3206 181 EEQLPELRKELEEAEAALEEFRQ-------------------------KNGLVDLSEEAKLLLQQLSELESQLAEARAEL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 392 VSVRSSLADTQQREASAYEQVKQVLQISEEANFEKtkaliQCDQLRKELERQAERLEKE---LASQQEKRAIEKDMMKKE 468
Cdd:COG3206 236 AEAEARLAALRAQLGSGPDALPELLQSPVIQQLRA-----QLAELEAELAELSARYTPNhpdVIALRAQIAALRAQLQQE 310
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 966924188 469 ITKERESMGSKMLILSQNIAQLEAQVEKVtKEKISAINQLEEIQSQLaSREMDVTK 524
Cdd:COG3206 311 AQRILASLEAELEALQAREASLQAQLAQL-EARLAELPELEAELRRL-EREVEVAR 364
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
459-591 |
1.04e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.54 E-value: 1.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 459 AIEKdMMKKEITKERESMGSKMLI-------LSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLAsremdvtkvcgEMRY 531
Cdd:COG2433 381 ALEE-LIEKELPEEEPEAEREKEHeerelteEEEEIRRLEEQVERLEAEVEELEAELEEKDERIE-----------RLER 448
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 532 QLNKAnmeKDEAEKEHREfraktNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAARARE 591
Cdd:COG2433 449 ELSEA---RSEERREIRK-----DREISRLDREIERLERELEEERERIEELKRKLERLKE 500
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
434-622 |
1.08e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.31 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 434 DQLRKELERQAERLEKELASQQekRAIEKDMMKKEITkereSMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQS 513
Cdd:COG3206 174 RKALEFLEEQLPELRKELEEAE--AALEEFRQKNGLV----DLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRA 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 514 QLASREMDVTKVCG-----EMRYQLNKANMEKDEAEK----EH--------------REFRAKTNRDLEIKDQEIEKLRI 570
Cdd:COG3206 248 QLGSGPDALPELLQspviqQLRAQLAELEAELAELSArytpNHpdvialraqiaalrAQLQQEAQRILASLEAELEALQA 327
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 966924188 571 ELGESKQHLEQEQQKAARAREECLRLTEL-----LGESEHQLHLTRQEKDSIQQSFS 622
Cdd:COG3206 328 REASLQAQLAQLEARLAELPELEAELRRLereveVARELYESLLQRLEEARLAEALT 384
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
201-652 |
2.11e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 41.64 E-value: 2.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 201 IHHLEAEVKFCKEELSGLKNKIQAVVLENESLQQELkSQRQEETLREQTLLDAsgnvqnswiTTGEDSGVGEAAKRPFSH 280
Cdd:pfam15921 386 LHKREKELSLEKEQNKRLWDRDTGNSITIDHLRREL-DDRNMEVQRLEALLKA---------MKSECQGQMERQMAAIQG 455
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 281 DNADIGKAASAGEQLELEK--LKLTYEEkyeiqesqLKFLRKDLAEYQRTCEDLKEQLKHKEFLLAANTSnrvaglclkc 358
Cdd:pfam15921 456 KNESLEKVSSLTAQLESTKemLRKVVEE--------LTAKKMTLESSERTVSDLTASLQEKERAIEATNA---------- 517
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 359 aqhEAVLSQTHNNVHMQTIERLMKERDDLMSAlvsvrssladtqQREASAYEqvkqvLQISEEanfektkaliqcDQLRK 438
Cdd:pfam15921 518 ---EITKLRSRVDLKLQELQHLKNEGDHLRNV------------QTECEALK-----LQMAEK------------DKVIE 565
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 439 ELERQAERLeKELASQQEKRA----IEKDMMKKEITKERESMGSKMLILSQN---IAQLEAQVEKVTKEKISAINQLEEI 511
Cdd:pfam15921 566 ILRQQIENM-TQLVGQHGRTAgamqVEKAQLEKEINDRRLELQEFKILKDKKdakIRELEARVSDLELEKVKLVNAGSER 644
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 512 QSQLASREMDVTKVCGEMRYQLNKANMEKDEAEKEHREFRAKTnrdlEIKDQEIEKLRIELGESKQHLE----------- 580
Cdd:pfam15921 645 LRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKS----EEMETTTNKLKMQLKSAQSELEqtrntlksmeg 720
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 581 ------------QEQQKAARAREECLR-----LTELLGESEHQLHLTRQEKDSIQQSFS------KEAKAQALQAQQREQ 637
Cdd:pfam15921 721 sdghamkvamgmQKQITAKRGQIDALQskiqfLEEAMTNANKEKHFLKEEKNKLSQELStvatekNKMAGELEVLRSQER 800
|
490
....*....|....*
gi 966924188 638 ELTQKIQQMEAQHDK 652
Cdd:pfam15921 801 RLKEKVANMEVALDK 815
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
546-776 |
2.43e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.46 E-value: 2.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 546 EHREFRAKTNRDLEIKDQEIEKLRI---ELGESKQHLEQEQQKAARAREeclrLTELLGESEHQLHLtrQEKDSIQQSfS 622
Cdd:COG1196 169 KYKERKEEAERKLEATEENLERLEDilgELERQLEPLERQAEKAERYRE----LKEELKELEAELLL--LKLRELEAE-L 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 623 KEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEecctLAKKLEQISQKTRSEIAQLSQEKRy 702
Cdd:COG1196 242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE----LLAELARLEQDIARLEERRRELEE- 316
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966924188 703 tydKLGKLQRRNEELEEQCVQHGRVHEIMKQRLRQLDKHSQATAQQLVQLLNKQNQLLLERQSLSEEVDRLRTQ 776
Cdd:COG1196 317 ---RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
410-549 |
2.58e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 41.35 E-value: 2.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 410 EQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKRAIEKDMMKKEITKEresmgskmlilsqnIAQ 489
Cdd:PRK00409 516 EKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQA--------------IKE 581
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 490 LEAQVEKVTKEkisAINQLEEIQSQLASREMDvtkvcgEMRYQLNKANMEKDEAEKEHRE 549
Cdd:PRK00409 582 AKKEADEIIKE---LRQLQKGGYASVKAHELI------EARKRLNKANEKKEKKKKKQKE 632
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
385-519 |
3.00e-03 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 40.42 E-value: 3.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 385 DDLMSALVSVRSSLADTQQREASAYEQVKQVLQISE-EANFEKTKAliQCDQLRKELERQAERLEKELASQQekraiekd 463
Cdd:COG1566 79 TDLQAALAQAEAQLAAAEAQLARLEAELGAEAEIAAaEAQLAAAQA--QLDLAQRELERYQALYKKGAVSQQ-------- 148
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 966924188 464 mmkkeitkERESMGSKMLILSQNIAQLEAQVEKvTKEKISAINQLEEIQSQLASRE 519
Cdd:COG1566 149 --------ELDEARAALDAAQAQLEAAQAQLAQ-AQAGLREEEELAAAQAQVAQAE 195
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
377-661 |
4.74e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 40.33 E-value: 4.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 377 IERLMKERDDLmsALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQE 456
Cdd:COG5185 255 LEKLVEQNTDL--RLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAEQELEESKR 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 457 KRAIEKDMMKKEITKERESMGSKMLILSQNIAQLEAQVEK-VTKEKISAIN-QLEEIQSQLASREMDVTKVCGEMRYQLN 534
Cdd:COG5185 333 ETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELsKSSEELDSFKdTIESTKESLDEIPQNQRGYAQEILATLE 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 535 KANMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELGESKQHLEQEQQK--AARAREECLRLTELLGESEHQLHLTRQ 612
Cdd:COG5185 413 DTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSrlEEAYDEINRSVRSKKEDLNEELTQIES 492
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 966924188 613 EKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLL 661
Cdd:COG5185 493 RVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILAL 541
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
428-592 |
5.28e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.14 E-value: 5.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 428 KALIQCDQLRKELERQAERLEKELAsQQEKRAIEKDMMKKEITKERESMGSKMLILSQNIAQLEAQVEKVTKEKisainQ 507
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELA-ALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNK-----E 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 508 LEEIQSQLASREMDVTkvcgemryQLNKANMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELGESKQHLEQEQQKAA 587
Cdd:COG1579 91 YEALQKEIESLKRRIS--------DLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELE 162
|
....*
gi 966924188 588 RAREE 592
Cdd:COG1579 163 AEREE 167
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
296-492 |
7.92e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 39.72 E-value: 7.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 296 ELEKLKLTYEEKYEIQESQLKFLRKDLAEYQRTCEDLKEQLKHKEFLLAANTSNRVAGLCLKCAQHEAVLSQTHNNV--H 373
Cdd:pfam17380 379 ELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEqeR 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 374 MQTIERLMKERDDLMSAlvsvRSSLADTQQREASAYEQVKQVLQISEEANfekTKALIQCDQLRKELERQAERLEKELAS 453
Cdd:pfam17380 459 QQQVERLRQQEEERKRK----KLELEKEKRDRKRAEEQRRKILEKELEER---KQAMIEEERKRKLLEKEMEERQKAIYE 531
|
170 180 190
....*....|....*....|....*....|....*....
gi 966924188 454 QQEKRAIEKDMMKKEITKERESMGSKMLILSQNIAQLEA 492
Cdd:pfam17380 532 EERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEA 570
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
196-724 |
8.03e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 40.03 E-value: 8.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 196 DQSQYIHHLEAEVKFCKEELSGLKNKIQAVVLENESLQQELKSQRQEETLREQTLLDASGNVQNSWittgedsgvgeaak 275
Cdd:TIGR00606 491 EKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKS-------------- 556
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 276 rpfSHDNADIGKAASAGEQLELEKLKLTYEEKYEIQESQLKFLRKDLAEYQRTCEDLKEQLKHKEFLLAAnTSNRVAGLC 355
Cdd:TIGR00606 557 ---RHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSS-YEDKLFDVC 632
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 356 lKCAQHEAVLSQTHnnvhmQTIERLMKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFE----KTKALI 431
Cdd:TIGR00606 633 -GSQDEESDLERLK-----EEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFisdlQSKLRL 706
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 432 QCDQLrKELERQAERLEK---ELASQQEKRAIEKDMMKKEITKERE---SMGSKMLILSQNIAQLEAQVEKVTKEKISAI 505
Cdd:TIGR00606 707 APDKL-KSTESELKKKEKrrdEMLGLAPGRQSIIDLKEKEIPELRNklqKVNRDIQRLKNDIEEQETLLGTIMPEEESAK 785
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 506 N-------------QLEEIQSQLASREMDVTKVCGEMRY-QLNKANMEKD----------EAEKEHREFRAKTNRDLEIK 561
Cdd:TIGR00606 786 VcltdvtimerfqmELKDVERKIAQQAAKLQGSDLDRTVqQVNQEKQEKQheldtvvskiELNRKLIQDQQEQIQHLKSK 865
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 562 DQEIEKLRIELGESKQHLEQEQQKAARAREECLRLTELLGESEHQ-------LHLTRQEKDSIQQSFSKEAKAQALQAQQ 634
Cdd:TIGR00606 866 TNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQdspletfLEKDQQEKEELISSKETSNKKAQDKVND 945
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966924188 635 REQELTQKIQQMEAQHDKTENEQYLLLTSQNTFLTKLK---EECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQ 711
Cdd:TIGR00606 946 IKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNaqlEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRK 1025
|
570
....*....|....*
gi 966924188 712 RRNE--ELEEQCVQH 724
Cdd:TIGR00606 1026 RENElkEVEEELKQH 1040
|
|
| |
