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Conserved domains on  [gi|967503439|ref|XP_014981955|]
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probable RNA polymerase II nuclear localization protein SLC7A6OS [Macaca mulatta]

Protein Classification

Iwr1 domain-containing protein( domain architecture ID 10554160)

Iwr1 domain-containing protein such as yeast RNA polymerase II nuclear localization protein Iwr1 which binds RNAP II and regulates nuclear import

Gene Ontology:  GO:0006606|GO:0005634|GO:0005737
PubMed:  21504834|21695216

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Iwr1 pfam08574
Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it ...
 194-257 1.93e-04

Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it interacts with with most of the polymerase II subunits. Deletion of this protein results in hypersensitivity to the K1 killer toxin.


:

Pssm-ID: 430085  Cd Length: 72  Bit Score: 39.17  E-value: 1.93e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 967503439  194 DDYVYDIYYLETATPGWIENILS-------VQPYSQEWELVNEDQEPEDIYDDEDD-ENSENNWRNEYPEEE 257
Cdd:pfam08574   1 DDYVYDVYVRVLEEENEADVPPAnvgvlviDEEDDDLLLFYGDDDDSDEDWDEDDEdSNAENYYRNDYPDEE 72
 
Name Accession Description Interval E-value
Iwr1 pfam08574
Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it ...
 194-257 1.93e-04

Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it interacts with with most of the polymerase II subunits. Deletion of this protein results in hypersensitivity to the K1 killer toxin.


Pssm-ID: 430085  Cd Length: 72  Bit Score: 39.17  E-value: 1.93e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 967503439  194 DDYVYDIYYLETATPGWIENILS-------VQPYSQEWELVNEDQEPEDIYDDEDD-ENSENNWRNEYPEEE 257
Cdd:pfam08574   1 DDYVYDVYVRVLEEENEADVPPAnvgvlviDEEDDDLLLFYGDDDDSDEDWDEDDEdSNAENYYRNDYPDEE 72
 
Name Accession Description Interval E-value
Iwr1 pfam08574
Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it ...
 194-257 1.93e-04

Transcription factor Iwr1; Iwr1 is involved in transcription from polymerase II promoters; it interacts with with most of the polymerase II subunits. Deletion of this protein results in hypersensitivity to the K1 killer toxin.


Pssm-ID: 430085  Cd Length: 72  Bit Score: 39.17  E-value: 1.93e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 967503439  194 DDYVYDIYYLETATPGWIENILS-------VQPYSQEWELVNEDQEPEDIYDDEDD-ENSENNWRNEYPEEE 257
Cdd:pfam08574   1 DDYVYDVYVRVLEEENEADVPPAnvgvlviDEEDDDLLLFYGDDDDSDEDWDEDDEdSNAENYYRNDYPDEE 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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