NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|966923721|ref|XP_014980597|]
View 

TIP41-like protein isoform X2 [Macaca mulatta]

Protein Classification

TIP41 family protein( domain architecture ID 10514483)

TIP41 family protein similar to Saccharomyces cerevisiae type 2A phosphatase activator TIP41 that is involved in negative regulation of the TOR signaling pathway in response to type of available nitrogen source

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TIP41 pfam04176
TIP41-like family; The TOR signalling pathway activates a cell-growth program in response to ...
 9-177 1.79e-88

TIP41-like family; The TOR signalling pathway activates a cell-growth program in response to nutrients. TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.


:

Pssm-ID: 461208  Cd Length: 168  Bit Score: 258.58  E-value: 1.79e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923721    9 FGDNVLRIQH-GSGFGIEFNATDALRCVNN-YQGMLKVACAEEWQESRTEGEHSKEVIKPYDWTYTTDYKGTLLGeslKL 86
Cdd:pfam04176   1 FGNNSLRLEHkPSGWTIEFNALDALKLVDKtGEEGLKVAYAKEWKKSREKSEGIKEVVKPYDWTYTTDYKGTLNG---GI 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923721   87 KVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIRVMPSSFFLLLRFFLRIDGVLIRMNDTRLYHEADK 166
Cdd:pfam04176  78 KVEPTEERIPIEKLKRPDPILFYDEVVLFEDELADNGISMLSVKIRVMPSCFFLLLRFFLRVDNVLFRIRDTRVYHEFGT 157

                         170
                  ....*....|.
gi 966923721  167 TYMLREYTSRE 177
Cdd:pfam04176 158 NYVIREYTGRE 168
 
Name Accession Description Interval E-value
TIP41 pfam04176
TIP41-like family; The TOR signalling pathway activates a cell-growth program in response to ...
 9-177 1.79e-88

TIP41-like family; The TOR signalling pathway activates a cell-growth program in response to nutrients. TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.


Pssm-ID: 461208  Cd Length: 168  Bit Score: 258.58  E-value: 1.79e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923721    9 FGDNVLRIQH-GSGFGIEFNATDALRCVNN-YQGMLKVACAEEWQESRTEGEHSKEVIKPYDWTYTTDYKGTLLGeslKL 86
Cdd:pfam04176   1 FGNNSLRLEHkPSGWTIEFNALDALKLVDKtGEEGLKVAYAKEWKKSREKSEGIKEVVKPYDWTYTTDYKGTLNG---GI 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923721   87 KVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIRVMPSSFFLLLRFFLRIDGVLIRMNDTRLYHEADK 166
Cdd:pfam04176  78 KVEPTEERIPIEKLKRPDPILFYDEVVLFEDELADNGISMLSVKIRVMPSCFFLLLRFFLRVDNVLFRIRDTRVYHEFGT 157

                         170
                  ....*....|.
gi 966923721  167 TYMLREYTSRE 177
Cdd:pfam04176 158 NYVIREYTGRE 168
 
Name Accession Description Interval E-value
TIP41 pfam04176
TIP41-like family; The TOR signalling pathway activates a cell-growth program in response to ...
 9-177 1.79e-88

TIP41-like family; The TOR signalling pathway activates a cell-growth program in response to nutrients. TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.


Pssm-ID: 461208  Cd Length: 168  Bit Score: 258.58  E-value: 1.79e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923721    9 FGDNVLRIQH-GSGFGIEFNATDALRCVNN-YQGMLKVACAEEWQESRTEGEHSKEVIKPYDWTYTTDYKGTLLGeslKL 86
Cdd:pfam04176   1 FGNNSLRLEHkPSGWTIEFNALDALKLVDKtGEEGLKVAYAKEWKKSREKSEGIKEVVKPYDWTYTTDYKGTLNG---GI 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923721   87 KVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIRVMPSSFFLLLRFFLRIDGVLIRMNDTRLYHEADK 166
Cdd:pfam04176  78 KVEPTEERIPIEKLKRPDPILFYDEVVLFEDELADNGISMLSVKIRVMPSCFFLLLRFFLRVDNVLFRIRDTRVYHEFGT 157

                         170
                  ....*....|.
gi 966923721  167 TYMLREYTSRE 177
Cdd:pfam04176 158 NYVIREYTGRE 168
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH