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Conserved domains on  [gi|967498760|ref|XP_014979751|]
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kinesin light chain 3 isoform X3 [Macaca mulatta]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
204-411 3.44e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.54  E-value: 3.44e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEdlerssghCHPDVATMLNILALVYRDQNKYKEATELLHDALQIreqtl 283
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALE--------LDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 284 gpeHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIRekvlgadhPDVAKQLNNLALLCQNQGKFEDVERHYARALSIy 363
Cdd:COG0457   72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 967498760 364 ealggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKEDLPAPL 411
Cdd:COG0457  140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLA 180
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
21-148 2.17e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 2.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760   21 EELVRQTRQVVQGLEALRAEHRGLAGHLAEALAGQgpvtgLEMLEEKQQVVSHSLEAIELGLGEAQVLLALSAHvgALEA 100
Cdd:COG4913   312 ERLEARLDALREELDELEAQIRGNGGDRLEQLERE-----IERLERELEERERRRARLEALLAALGLPLPASAE--EFAA 384

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 967498760  101 EKQRLRSQARRLAQENVWLREELEETQRRLRASEEAVAQLEEEKRHLE 148
Cdd:COG4913   385 LRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLE 432
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
204-411 3.44e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.54  E-value: 3.44e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEdlerssghCHPDVATMLNILALVYRDQNKYKEATELLHDALQIreqtl 283
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALE--------LDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 284 gpeHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIRekvlgadhPDVAKQLNNLALLCQNQGKFEDVERHYARALSIy 363
Cdd:COG0457   72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 967498760 364 ealggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKEDLPAPL 411
Cdd:COG0457  140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLA 180
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 204-397 7.90e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 93.06  E-value: 7.90e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIREQTL 283
Cdd:NF040586 517 PRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVL 596

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 284 -GPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSI 362
Cdd:NF040586 597 gGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDTLAAALSLANDLRALGDADEARELAREVLDR 676

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 967498760 363 YEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEEL 397
Cdd:NF040586 677 YRRVLGEDHPFTLACRNNLAVLLRALGDPEEAREL 711
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 220-450 4.86e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 90.75  E-value: 4.86e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 220 QGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDAL--QIREQTLGPEHPAVAATLNNL 297
Cdd:NF040586 405 RGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLerQRRVLGLGEDHPHTLMTAGGL 484

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 298 AVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKT 377
Cdd:NF040586 485 GADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLS 564

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 378 KNNLASAYLKQNKYQQAEEL-------YKEILHKEDLPAPLGApntgtAGDTEQALRRSSSLSKIRESIRRGSEKLVSRL 450
Cdd:NF040586 565 ANNLARDLRELGRYAEALDLleealerYREVLGGPDHPDTLRA-----AKSLAVALRRAGRLEEALELAEDTYERYRRRF 639
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 219-450 1.08e-16

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 83.43  E-value: 1.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 219 GQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIREQTLGPEHPAVAATLNNLA 298
Cdd:NF040586 490 ALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLA 569

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 299 VLYGKRGRYREAEPLCQRALEIREKVL-GADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKT 377
Cdd:NF040586 570 RDLRELGRYAEALDLLEEALERYREVLgGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDTLAA 649

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 967498760 378 KNNLASAYLKQNKYQQAEELYKEILHkeDLPAPLGA--PNT-GTAGDTEQALRRSSSLSKIRESIRRGSEKLVSRL 450
Cdd:NF040586 650 ALSLANDLRALGDADEARELAREVLD--RYRRVLGEdhPFTlACRNNLAVLLRALGDPEEARELAEAALEGLRERL 723
TPR_12 pfam13424
Tetratricopeptide repeat;
247-323 6.96e-16

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 72.42  E-value: 6.96e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 967498760  247 DVATMLNILALVYRDQNKYKEATELLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREK 323
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 204-340 1.47e-15

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 79.58  E-value: 1.47e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPD-VATMLNiLALVYRDQNKYKEATELLHDALQIREQT 282
Cdd:NF040586 602 PDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARELAREVLDRYRRV 680

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 967498760 283 LGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLA 340
Cdd:NF040586 681 LGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEGLRERLGPDHPYTLAAAVNLA 738
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 245-402 7.02e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.01  E-value: 7.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760  245 HPDVATMLNILALVYRDQNKYKEATELLHDALQIreqtlgpeHPAVAATLNNLAVLYGKRGRYReAEPLCQRALEIRekv 324
Cdd:TIGR02917 766 HPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKK--------APDNAVVLNNLAWLYLELKDPR-ALEYAERALKLA--- 833

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 967498760  325 lgadhPDVAKQLNNLALLCQNQGKFEDVERHYARALSIyealggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Cdd:TIGR02917 834 -----PNIPAILDTLGWLLVEKGEADRALPLLRKAVNI--------APEAAAIRYHLALALLATGRKAEARKELDKLL 898
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
21-148 2.17e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 2.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760   21 EELVRQTRQVVQGLEALRAEHRGLAGHLAEALAGQgpvtgLEMLEEKQQVVSHSLEAIELGLGEAQVLLALSAHvgALEA 100
Cdd:COG4913   312 ERLEARLDALREELDELEAQIRGNGGDRLEQLERE-----IERLERELEERERRRARLEALLAALGLPLPASAE--EFAA 384

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 967498760  101 EKQRLRSQARRLAQENVWLREELEETQRRLRASEEAVAQLEEEKRHLE 148
Cdd:COG4913   385 LRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLE 432
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 291-323 3.80e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.81  E-value: 3.80e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 967498760   291 AATLNNLAVLYGKRGRYREAEPLCQRALEIREK 323
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 61-148 9.55e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 9.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760    61 LEMLEEKQQVVSHSLEAIELGLGEAQ--------VLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRA 132
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEeeieelqkELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE 334

                           90
                   ....*....|....*.
gi 967498760   133 SEEAVAQLEEEKRHLE 148
Cdd:TIGR02168  335 LAEELAELEEKLEELK 350
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 97-185 3.33e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 40.32  E-value: 3.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760   97 ALEAEKQRLRSQARRLAQENVWLREELEETQRRLRASEEAVAQLEEEKRHLEF-LGQLRQYDPPTETQQSESPPRRDSLA 175
Cdd:PRK11448  146 ALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAqLEQLQEKAAETSQERKQKRKEITDQA 225

                          90
                  ....*....|..
gi 967498760  176 S--LFPSEEEER 185
Cdd:PRK11448  226 AkrLELSEEETR 237
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
204-411 3.44e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.54  E-value: 3.44e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEdlerssghCHPDVATMLNILALVYRDQNKYKEATELLHDALQIreqtl 283
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALE--------LDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 284 gpeHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIRekvlgadhPDVAKQLNNLALLCQNQGKFEDVERHYARALSIy 363
Cdd:COG0457   72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 967498760 364 ealggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKEDLPAPL 411
Cdd:COG0457  140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLA 180
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 204-397 7.90e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 93.06  E-value: 7.90e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIREQTL 283
Cdd:NF040586 517 PRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVL 596

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 284 -GPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSI 362
Cdd:NF040586 597 gGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDTLAAALSLANDLRALGDADEARELAREVLDR 676

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 967498760 363 YEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEEL 397
Cdd:NF040586 677 YRRVLGEDHPFTLACRNNLAVLLRALGDPEEAREL 711
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 220-450 4.86e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 90.75  E-value: 4.86e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 220 QGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDAL--QIREQTLGPEHPAVAATLNNL 297
Cdd:NF040586 405 RGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLerQRRVLGLGEDHPHTLMTAGGL 484

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 298 AVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKT 377
Cdd:NF040586 485 GADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLS 564

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 378 KNNLASAYLKQNKYQQAEEL-------YKEILHKEDLPAPLGApntgtAGDTEQALRRSSSLSKIRESIRRGSEKLVSRL 450
Cdd:NF040586 565 ANNLARDLRELGRYAEALDLleealerYREVLGGPDHPDTLRA-----AKSLAVALRRAGRLEEALELAEDTYERYRRRF 639
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 220-411 1.64e-18

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 88.90  E-value: 1.64e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 220 QGRYEVAVPLCRQALEDlerssghcHPDVATMLNILALVYRDQNKYKEATELLHDALQIreqtlgpeHPAVAATLNNLAV 299
Cdd:COG3914   91 LGRYEEALALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDFAEAYLNLGE 154

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 300 LYGKRGRYREAEPLCQRALEIRekvlgadhPDVAKQLNNLALLCQNQGKFEDVERHYARALSIyealggphDPNVAKTKN 379
Cdd:COG3914  155 ALRRLGRLEEAIAALRRALELD--------PDNAEALNNLGNALQDLGRLEEAIAAYRRALEL--------DPDNADAHS 218

                        170       180       190
                 ....*....|....*....|....*....|..
gi 967498760 380 NLASAYLKQNKYQQAEELYKEILHKEDLPAPL 411
Cdd:COG3914  219 NLLFALRQACDWEVYDRFEELLAALARGPSEL 250
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 202-402 3.09e-17

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 84.66  E-value: 3.09e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 202 EIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSsgHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIreq 281
Cdd:COG3914   33 EAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAA--AALLLLAALLELAALLLQALGRYEEALALYRRALAL--- 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 282 tlgpeHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIrekvlgadHPDVAKQLNNLALLCQNQGKFEDVERHYARALS 361
Cdd:COG3914  108 -----NPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDFAEAYLNLGEALRRLGRLEEAIAALRRALE 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 967498760 362 IyealggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Cdd:COG3914  175 L--------DPDNAEALNNLGNALQDLGRLEEAIAAYRRAL 207
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 219-450 1.08e-16

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 83.43  E-value: 1.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 219 GQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIREQTLGPEHPAVAATLNNLA 298
Cdd:NF040586 490 ALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLA 569

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 299 VLYGKRGRYREAEPLCQRALEIREKVL-GADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKT 377
Cdd:NF040586 570 RDLRELGRYAEALDLLEEALERYREVLgGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDTLAA 649

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 967498760 378 KNNLASAYLKQNKYQQAEELYKEILHkeDLPAPLGA--PNT-GTAGDTEQALRRSSSLSKIRESIRRGSEKLVSRL 450
Cdd:NF040586 650 ALSLANDLRALGDADEARELAREVLD--RYRRVLGEdhPFTlACRNNLAVLLRALGDPEEARELAEAALEGLRERL 723
TPR_12 pfam13424
Tetratricopeptide repeat;
247-323 6.96e-16

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 72.42  E-value: 6.96e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 967498760  247 DVATMLNILALVYRDQNKYKEATELLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREK 323
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
204-400 1.30e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.58  E-value: 1.30e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDlerssghcHPDVATMLNILALVYRDQNKYKEATELLHDALQIReqtl 283
Cdd:COG0457   39 PDDAEALYNLGLAYLRLGRYEEALADYEQALEL--------DPDDAEALNNLGLALQALGRYEEALEDYDKALELD---- 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 284 gpehPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIRekvlgadhPDVAKQLNNLALLCQNQGKFEDVERHYARALSIY 363
Cdd:COG0457  107 ----PDDAEALYNLGLALLELGRYDEAIEAYERALELD--------PDDADALYNLGIALEKLGRYEEALELLEKLEAAA 174

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 967498760 364 EALGGPHDPNVAKTKNNLASAYLKQNKYQQAEELYKE 400
Cdd:COG0457  175 LAALLAAALGEAALALAAAEVLLALLLALEQALRKKL 211
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 204-340 1.47e-15

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 79.58  E-value: 1.47e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPD-VATMLNiLALVYRDQNKYKEATELLHDALQIREQT 282
Cdd:NF040586 602 PDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARELAREVLDRYRRV 680

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 967498760 283 LGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLA 340
Cdd:NF040586 681 LGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEGLRERLGPDHPYTLAAAVNLA 738
TPR_12 pfam13424
Tetratricopeptide repeat;
290-365 1.64e-15

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 71.26  E-value: 1.64e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 967498760  290 VAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEA 365
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 204-358 4.29e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.56  E-value: 4.29e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEdlerssghCHPDVATMLNILALVYRDQNKYKEATELLHDALQIReqtl 283
Cdd:COG3914  109 PDNAEALFNLGNLLLALGRLEEALAALRRALA--------LNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELD---- 176

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 967498760 284 gPEHPAVaatLNNLAVLYGKRGRYREAEPLCQRALEIrekvlgadHPDVAKQLNNLALLCQNQGKFEDVERHYAR 358
Cdd:COG3914  177 -PDNAEA---LNNLGNALQDLGRLEEAIAAYRRALEL--------DPDNADAHSNLLFALRQACDWEVYDRFEEL 239
TPR_10 pfam13374
Tetratricopeptide repeat;
290-331 7.32e-13

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 62.52  E-value: 7.32e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 967498760  290 VAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPD 331
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 217-405 4.33e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.68  E-value: 4.33e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 217 YAGQGRYEVAVPLCRQALEDlerssghcHPDVATMLNILALVYRDQNKYKEATELLHDALQIReqtlgpehPAVAATLNN 296
Cdd:COG2956   52 YRRRGEYDRAIRIHQKLLER--------DPDRAEALLELAQDYLKAGLLDRAEELLEKLLELD--------PDDAEALRL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 297 LAVLYGKRGRYREAEPLCQRALEIrekvlgadHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIyealggphDPNVAK 376
Cdd:COG2956  116 LAEIYEQEGDWEKAIEVLERLLKL--------GPENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCAR 179

                        170       180
                 ....*....|....*....|....*....
gi 967498760 377 TKNNLASAYLKQNKYQQAEELYKEILHKE 405
Cdd:COG2956  180 ALLLLAELYLEQGDYEEAIAALERALEQD 208
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 204-411 7.40e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.91  E-value: 7.40e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDlerssghcHPDVATMLNILALVYRDQNKYKEATELLHDALQIreqtl 283
Cdd:COG2956   73 PDRAEALLELAQDYLKAGLLDRAEELLEKLLEL--------DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL----- 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 284 gpeHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIrekvlgadHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIy 363
Cdd:COG2956  140 ---GPENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCARALLLLAELYLEQGDYEEAIAALERALEQ- 207

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 967498760 364 ealggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKEDLPAPL 411
Cdd:COG2956  208 -------DPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL 248
TPR_12 pfam13424
Tetratricopeptide repeat;
331-402 2.17e-11

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 59.71  E-value: 2.17e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 967498760  331 DVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERAL 72
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 205-363 1.33e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.44  E-value: 1.33e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 205 ARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDlerssghcHPDVATMLNILALVYRDQNKYKEATELLHDALQIreqtlg 284
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL------ 67

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 967498760 285 peHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEirekvLGADHPDVakqLNNLALLCQNQGKFEDVERHYARALSIY 363
Cdd:COG4783   68 --DPDEPEARLNLGLALLKAGDYDEALALLEKALK-----LDPEHPEA---YLRLARAYRALGRPDEAIAALEKALELD 136
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 254-406 1.50e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.05  E-value: 1.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 254 ILALVYRDQNKYKEATELLHDALQIreqtlgpeHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIrekvlgadHPDVA 333
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALEL--------DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER--------DPDRA 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 967498760 334 KQLNNLALLCQNQGKFEDVERHYARALSIyealggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKED 406
Cdd:COG2956   77 EALLELAQDYLKAGLLDRAEELLEKLLEL--------DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGP 141
TPR_10 pfam13374
Tetratricopeptide repeat;
248-288 1.03e-09

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 53.66  E-value: 1.03e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 967498760  248 VATMLNILALVYRDQNKYKEATELLHDALQIREQTLGPEHP 288
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHP 41
TPR_12 pfam13424
Tetratricopeptide repeat;
206-281 1.76e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 54.32  E-value: 1.76e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 967498760  206 RLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIREQ 281
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 255-405 1.81e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.97  E-value: 1.81e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 255 LALVYRDQNKYKEATELLHDALQireqtlgpEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIrekvlgadHPDVAK 334
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALE--------LDPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL--------DPDEPE 73

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 967498760 335 QLNNLALLCQNQGKFEDVERHYARALSIyealggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKE 405
Cdd:COG4783   74 ARLNLGLALLKAGDYDEALALLEKALKL--------DPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
204-365 2.96e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.71  E-value: 2.96e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEdlerssghCHPDVATMLNILALVYRDQNKYKEATELLHDALQIReqtl 283
Cdd:COG0457   73 PDDAEALNNLGLALQALGRYEEALEDYDKALE--------LDPDDAEALYNLGLALLELGRYDEAIEAYERALELD---- 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 284 gpehPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIY 363
Cdd:COG0457  141 ----PDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTL 216


                 ..
gi 967498760 364 EA 365
Cdd:COG0457  217 AA 218
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
300-405 1.04e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 52.48  E-value: 1.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 300 LYGKRGRYREAEPLCQRALEIrekvlgadHPDVAKQLNNLALLCQNQGKFEDVERhYARALSIyealggphDPNVAKTKN 379
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIA-LEKALKL--------DPNNAEALL 63

                         90       100
                 ....*....|....*....|....*.
gi 967498760 380 NLASAYLKQNKYQQAEELYKEILHKE 405
Cdd:COG3063   64 NLAELLLELGDYDEALAYLERALELD 89
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
258-366 3.73e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.94  E-value: 3.73e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 258 VYRDQNKYKEATELLHDALQIreqtlgpeHPAVAATLNNLAVLYGKRGRYREAEPLcQRALEIrekvlgadHPDVAKQLN 337
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALL 63

                         90       100
                 ....*....|....*....|....*....
gi 967498760 338 NLALLCQNQGKFEDVERHYARALSIYEAL 366
Cdd:COG3063   64 NLAELLLELGDYDEALAYLERALELDPSA 92
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 249-407 6.45e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 51.88  E-value: 6.45e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 249 ATMLNILALVYRDQNKYKEATELLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIrekvlgad 328
Cdd:COG5010   12 LYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL-------- 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 967498760 329 HPDVAKQLNNLALLCQNQGKFEDVERHYARALSIyealggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKEDL 407
Cdd:COG5010   84 DPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL--------SPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 286-402 7.86e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 7.86e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 286 EHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIRekvlgadhPDVAKQLNNLALLCQNQGKFEDVERHYARALSIyea 365
Cdd:COG4235   12 ANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAEELLERALAL--- 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 967498760 366 lggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Cdd:COG4235   81 -----DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLL 112
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
217-325 1.02e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.78  E-value: 1.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 217 YAGQGRYEVAVPLCRQALEDlerssghcHPDVATMLNILALVYRDQNKYKEATELlHDALQIreqtlgpeHPAVAATLNN 296
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALLN 64

                         90       100
                 ....*....|....*....|....*....
gi 967498760 297 LAVLYGKRGRYREAEPLCQRALEIREKVL 325
Cdd:COG3063   65 LAELLLELGDYDEALAYLERALELDPSAL 93
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
212-399 1.25e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 52.61  E-value: 1.25e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 212 NLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIReqtlgpehPAVA 291
Cdd:COG4785   36 ALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLA 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 292 ATLNNLAVLYGKRGRYREAEPLCQRALEIRekvlgadhPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPH- 370
Cdd:COG4785  108 EAYNNRGLAYLLLGDYDAALEDFDRALELD--------PDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERAl 179

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 967498760 371 ---------DPNVAKT--KNNLASAYLKQNKYQQAEELYK 399
Cdd:COG4785  180 wlylaerklDPEKALAllLEDWATAYLLQGDTEEARELFK 219
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 289-402 4.44e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.03  E-value: 4.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 289 AVAATLNNLAVLYGKRGRYREAEPLCQRALEIrekvlgadHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIyealgg 368
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL------ 67

                         90       100       110
                 ....*....|....*....|....*....|....
gi 967498760 369 phDPNVAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Cdd:COG4783   68 --DPDEPEARLNLGLALLKAGDYDEALALLEKAL 99
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 245-402 7.02e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.01  E-value: 7.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760  245 HPDVATMLNILALVYRDQNKYKEATELLHDALQIreqtlgpeHPAVAATLNNLAVLYGKRGRYReAEPLCQRALEIRekv 324
Cdd:TIGR02917 766 HPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKK--------APDNAVVLNNLAWLYLELKDPR-ALEYAERALKLA--- 833

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 967498760  325 lgadhPDVAKQLNNLALLCQNQGKFEDVERHYARALSIyealggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Cdd:TIGR02917 834 -----PNIPAILDTLGWLLVEKGEADRALPLLRKAVNI--------APEAAAIRYHLALALLATGRKAEARKELDKLL 898
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 204-362 2.71e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.26  E-value: 2.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIreqtl 283
Cdd:COG5010    9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL----- 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 967498760 284 gpeHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIrekvlgadHPDVAKQLNNLALLCQNQGKFEDVERHYARALSI 362
Cdd:COG5010   84 ---DPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL--------SPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 255-402 4.39e-06

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 48.10  E-value: 4.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760  255 LALVYRDQNKYKEATELLHDALQIReqtlgpehPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIrekvlgadHPDVAK 334
Cdd:TIGR02521  37 LALGYLEQGDLEVAKENLDKALEHD--------PDDYLAYLALALYYQQLGELEKAEDSFRRALTL--------NPNNGD 100

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 967498760  335 QLNNL-ALLCQnQGKFEDVERHYARALSiyealgGPHDPNVAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Cdd:TIGR02521 101 VLNNYgTFLCQ-QGKYEQAMQQFEQAIE------DPLYPQPARSLENAGLCALKAGDFDKAEKYLTRAL 162
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
255-403 6.32e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 47.22  E-value: 6.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 255 LALVYRDQNKYKEATELLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIRekvlgadhPDVAK 334
Cdd:COG4785   37 LAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLAE 108

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 967498760 335 QLNNLALLCQNQGKFEDVERHYARALSIyealggphDPNVAKTKNNLASAYLKQNKYQQAEELYKEILH 403
Cdd:COG4785  109 AYNNRGLAYLLLGDYDAALEDFDRALEL--------DPDYAYAYLNRGIALYYLGRYELAIADLEKALE 169
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 303-428 2.78e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.44  E-value: 2.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 303 KRGRYREAEPLCQRALEirekvLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYealggPHDPNVAKTKNNLA 382
Cdd:COG1729    5 KAGDYDEAIAAFKAFLK-----RYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRY-----PDSPKAPDALLKLG 74

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 967498760 383 SAYLKQNKYQQAEELYKEILHKedlpaplgAPNTGTAGDTEQALRR 428
Cdd:COG1729   75 LSYLELGDYDKARATLEELIKK--------YPDSEAAKEARARLAR 112
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 204-320 3.04e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.03  E-value: 3.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDlerssghcHPDVATMLNILALVYRDQNKYKEATELLHDALQireqtL 283
Cdd:COG4783   35 PDNPEAFALLGEILLQLGDLDEAIVLLHEALEL--------DPDEPEARLNLGLALLKAGDYDEALALLEKALK-----L 101

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 967498760 284 GPEHPAVaatLNNLAVLYGKRGRYREAEPLCQRALEI 320
Cdd:COG4783  102 DPEHPEA---YLRLARAYRALGRPDEAIAALEKALEL 135
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 204-320 3.23e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.46  E-value: 3.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLerssghchPDVATMLNILALVYRDQNKYKEATELLHDALQireqtL 283
Cdd:COG4235   14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAEELLERALA-----L 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 967498760 284 GPEHPAVaatLNNLAVLYGKRGRYREAEPLCQRALEI 320
Cdd:COG4235   81 DPDNPEA---LYLLGLAAFQQGDYAEAIAAWQKLLAL 114
TPR_1 pfam00515
Tetratricopeptide repeat;
291-323 9.50e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.33  E-value: 9.50e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 967498760  291 AATLNNLAVLYGKRGRYREAEPLCQRALEIREK 323
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
21-148 2.17e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 2.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760   21 EELVRQTRQVVQGLEALRAEHRGLAGHLAEALAGQgpvtgLEMLEEKQQVVSHSLEAIELGLGEAQVLLALSAHvgALEA 100
Cdd:COG4913   312 ERLEARLDALREELDELEAQIRGNGGDRLEQLERE-----IERLERELEERERRRARLEALLAALGLPLPASAE--EFAA 384

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 967498760  101 EKQRLRSQARRLAQENVWLREELEETQRRLRASEEAVAQLEEEKRHLE 148
Cdd:COG4913   385 LRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLE 432
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 204-359 3.22e-04

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 42.68  E-value: 3.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760  204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQAlEDLERSSGHCHPDVATMLnILALVYRDQNKYKEATELLHDALQIREQTL 283
Cdd:pfam17874  37 LARGLATFVLGEAYLCLGDLDAALQAMREA-EALARRADSPHVTLWALL-QQGEILRAQGRLHQALETYQQALQLARDHG 114

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 967498760  284 GPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVlgadHPDVAKQLNN-LALLCQNQGKFEDVERHYARA 359
Cdd:pfam17874 115 LQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQLGRQW----EPDAAVDAYVlLARIALAQGELEEALTLLRRA 187
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 291-323 3.80e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.81  E-value: 3.80e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 967498760   291 AATLNNLAVLYGKRGRYREAEPLCQRALEIREK 323
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_7 pfam13176
Tetratricopeptide repeat;
293-328 3.85e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 37.90  E-value: 3.85e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 967498760  293 TLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGAD 328
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 315-402 4.72e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.37  E-value: 4.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 315 QRALEIREKVlgADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIyealggphDPNVAKTKNNLASAYLKQNKYQQA 394
Cdd:COG4235    1 EAIARLRQAL--AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRL--------DPDNADALLDLAEALLAAGDTEEA 70


                 ....*...
gi 967498760 395 EELYKEIL 402
Cdd:COG4235   71 EELLERAL 78
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 21-148 5.77e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 5.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760  21 EELVRQTRQVVQGLEALRAEHRGLAGHLAEALAGqgpvtgLEMLEEKQQVVSHSLEAIELGLGEAQ-VLLALSAHVGALE 99
Cdd:COG1196  228 ELLLLKLRELEAELEELEAELEELEAELEELEAE------LAELEAELEELRLELEELELELEEAQaEEYELLAELARLE 301

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 967498760 100 AEKQRLRSQARRLAQENVWLREELEETQRRLRASEEAVAQLEEEKRHLE 148
Cdd:COG1196  302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 289-406 5.81e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.64  E-value: 5.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 289 AVAATLNNLAVLYGKRGRYREAEPLCQRALEIrekvlgadHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIyealgg 368
Cdd:COG2956    6 AAALGWYFKGLNYLLNGQPDKAIDLLEEALEL--------DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER------ 71

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 967498760 369 phDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKED 406
Cdd:COG2956   72 --DPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDP 107
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 259-384 9.48e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.82  E-value: 9.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 259 YRDQNKYKEATELLHDALQireqtLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEirekvLGADHPDVAKQLNN 338
Cdd:COG1729    3 LLKAGDYDEAIAAFKAFLK-----RYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLK-----RYPDSPKAPDALLK 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 967498760 339 LALLCQNQGKFEDVERHYARALSIYealggPHDPNVAKTKNNLASA 384
Cdd:COG1729   73 LGLSYLELGDYDKARATLEELIKKY-----PDSEAAKEARARLARL 113
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 61-148 9.55e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 9.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760    61 LEMLEEKQQVVSHSLEAIELGLGEAQ--------VLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRA 132
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEeeieelqkELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE 334

                           90
                   ....*....|....*.
gi 967498760   133 SEEAVAQLEEEKRHLE 148
Cdd:TIGR02168  335 LAEELAELEEKLEELK 350
TPR_10 pfam13374
Tetratricopeptide repeat;
332-373 1.09e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 36.71  E-value: 1.09e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 967498760  332 VAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPN 373
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 204-321 1.16e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDlerssghcHPDVATMLNILALVYRDQNKYKEATELLHDALQireqtl 283
Cdd:COG2956  175 PDCARALLLLAELYLEQGDYEEAIAALERALEQ--------DPDYLPALPRLAELYEKLGDPEEALELLRKALE------ 240

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 967498760 284 gpEHPAVAAtLNNLAVLYGKRGRYREAEPLCQRALEIR 321
Cdd:COG2956  241 --LDPSDDL-LLALADLLERKEGLEAALALLERQLRRH 275
TPR_10 pfam13374
Tetratricopeptide repeat;
207-247 1.75e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 36.33  E-value: 1.75e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 967498760  207 LRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPD 247
Cdd:pfam13374   2 ASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
34-148 1.82e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760   34 LEALRAEHRGLAGHLAEAlagQGPVTGLEMLEEKQQVVSHSLEAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLA 113
Cdd:COG4913   612 LAALEAELAELEEELAEA---EERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLA 688

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 967498760  114 QenvwLREELEETQRRLRASEEAVAQLEEEKRHLE 148
Cdd:COG4913   689 A----LEEQLEELEAELEELEEELDELKGEIGRLE 719
TPR_1 pfam00515
Tetratricopeptide repeat;
375-402 2.16e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.86  E-value: 2.16e-03
                          10        20
                  ....*....|....*....|....*...
gi 967498760  375 AKTKNNLASAYLKQNKYQQAEELYKEIL 402
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKAL 28
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
292-402 2.62e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.51  E-value: 2.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760 292 ATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIyealggphD 371
Cdd:COG4785   32 AAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALEL--------D 103

                         90       100       110
                 ....*....|....*....|....*....|.
gi 967498760 372 PNVAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Cdd:COG4785  104 PDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 216-402 2.76e-03

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 39.99  E-value: 2.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760  216 QYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIREQtlGPEHPAVAATLN 295
Cdd:pfam17874  89 ILRAQGRLHQALETYQQALQLARDHGLQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQLGRQ--WEPDAAVDAYVL 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760  296 nLAVLYGKRGRYREAEPLCQRALEI--REKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALggphdpn 373
Cdd:pfam17874 167 -LARIALAQGELEEALTLLRRAELLarQSFFHVDWLANAERVRVRLWLARGDLRAAVRWLRAAEPPSDADNHF------- 238

                         170       180
                  ....*....|....*....|....*....
gi 967498760  374 VAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Cdd:pfam17874 239 LERELRNLARVLLALGRFDDALSLLERLQ 267
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 97-185 3.33e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 40.32  E-value: 3.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760   97 ALEAEKQRLRSQARRLAQENVWLREELEETQRRLRASEEAVAQLEEEKRHLEF-LGQLRQYDPPTETQQSESPPRRDSLA 175
Cdd:PRK11448  146 ALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAqLEQLQEKAAETSQERKQKRKEITDQA 225

                          90
                  ....*....|..
gi 967498760  176 S--LFPSEEEER 185
Cdd:PRK11448  226 AkrLELSEEETR 237
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 375-402 5.47e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 5.47e-03
                           10        20
                   ....*....|....*....|....*...
gi 967498760   375 AKTKNNLASAYLKQNKYQQAEELYKEIL 402
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKAL 28
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 34-148 6.65e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.15  E-value: 6.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760  34 LEALRAEHRGLAGHLAEALAGQgpvtgLEMLEEKQQVVSHSLEAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLA 113
Cdd:COG1196  353 LEEAEAELAEAEEALLEAEAEL-----AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 967498760 114 QENVWLREELEETQRRLRASEEAVAQLEEEKRHLE 148
Cdd:COG1196  428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 21-148 7.37e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.15  E-value: 7.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967498760  21 EELVRQTRQVVQGLEALRAEHRGLAGHLAEALAGqgpvtgLEMLEEKQQVVSHSLEAIELGLGEAQVLLAlsahvgALEA 100
Cdd:COG1196  256 EELEAELAELEAELEELRLELEELELELEEAQAE------EYELLAELARLEQDIARLEERRRELEERLE------ELEE 323

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 967498760 101 EKQRLRSQARRLAQENVWLREELEETQRRLRASEEAVAQLEEEKRHLE 148
Cdd:COG1196  324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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