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Conserved domains on  [gi|1622834689|ref|XP_014978932|]
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rootletin isoform X3 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
156-332 2.64e-53

Ciliary rootlet component, centrosome cohesion;


:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 185.24  E-value: 2.64e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  156 RRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRNT-------------EHSQDLESALIRL 222
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELLLRkltleprlqrlerEHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  223 EEEQQRSASLAQVNAMLREQLDQAGLANQALSEDIRKVTSDWARSRKELEQREAAWRREEESFNAYFSNEHSRLLLLWRQ 302
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1622834689  303 VVGFRRLVSEVKMFTERDLLQLGGELARTS 332
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 530-1057 1.71e-27

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 121.97  E-value: 1.71e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  530 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLA 609
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  610 HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREAL 689
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  690 SRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAAL 769
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  770 QGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQE 849
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  850 LEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREH 929
Cdd:COG1196    542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  930 LEAE--GQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWR 1007
Cdd:COG1196    622 LLGRtlVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1008 ELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAE 1057
Cdd:COG1196    702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 818-1374 1.03e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 116.19  E-value: 1.03e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  818 LEQQLPTLRHERSRlqeqlAQLSRQLSGREQELEQARRAAQRQ--MEALERAAREKEALAKERAGLAVQLAAAEREGRTL 895
Cdd:COG1196    198 LERQLEPLERQAEK-----AERYRELKEELKELEAELLLLKLRelEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  896 SEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKAS--LDKELMAQKL 973
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEelEEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  974 VQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE---------ELLARLEAEKEELSEEIAT 1044
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEleeaeeallERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1045 LQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQL 1124
Cdd:COG1196    433 LEEEEEE-EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1125 EEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKL-----RESQEGREVQRQEAG 1199
Cdd:COG1196    512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratfLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1200 ELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEAR 1279
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1280 RELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEF 1359
Cdd:COG1196    672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                          570
                   ....*....|....*
gi 1622834689 1360 RTRERRLLGSLEEAR 1374
Cdd:COG1196    752 ALEELPEPPDLEELE 766
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1054-1857 3.41e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 3.41e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1054 LLAESEKQQALSLKESEKT----ALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD-RSTVNALTSELRDLRAQLEEAV 1128
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAerykELKAELRELELALLVLRLEELREELEELQEELKEaEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1129 AAHaqevRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEG 1208
Cdd:TIGR02168  274 LEV----SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1209 AKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRR- 1287
Cdd:TIGR02168  350 KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKk 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1288 ----QMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1363
Cdd:TIGR02168  430 leeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1364 RRLLGSLEEA--RGTEKQQLDHARGLELKLEATraeaaeLGLRLSAAEGRaqGLEAELARVEAQR-----RAAEAQLGGL 1436
Cdd:TIGR02168  510 ALLKNQSGLSgiLGVLSELISVDEGYEAAIEAA------LGGRLQAVVVE--NLNAAKKAIAFLKqnelgRVTFLPLDSI 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1437 RSALRRGLGLGRAPS------PAPRPVPGSPARDAAAGGSGDGLSSPSNLECSPGSQPPSPGPATSPAppdLDPETVR-- 1508
Cdd:TIGR02168  582 KGTEIQGNDREILKNiegflgVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVT---LDGDLVRpg 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1509 ----GALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDhatlrarQLQKAVAESEEARRSVDGRLSGVQAEMALQ 1584
Cdd:TIGR02168  659 gvitGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALA-------ELRKELEELEEELEQLRKELEELSRQISAL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1585 EESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSsaslns 1744
Cdd:TIGR02168  812 LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL------ 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1745 tqdknlhlqkaltacEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQE 1824
Cdd:TIGR02168  886 ---------------EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950

                          810       820       830
                   ....*....|....*....|....*....|....
gi 1622834689 1825 GEA-AALHMVQKLQDERRLLQERLGSLQRALAQL 1857
Cdd:TIGR02168  951 LTLeEAEALENKIEDDEEEARRRLKRLENKIKEL 984
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1768-1997 5.84e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 5.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1768 ERLDAARQALSEARkqssslgEQVQTLRgEVADLELQQVEAEGQLQQLREVLRQRQegeaaalhmVQKLQDERRLLQERL 1847
Cdd:COG4913    235 DDLERAHEALEDAR-------EQIELLE-PIRELAERYAAARERLAELEYLRAALR---------LWFAQRRLELLEAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1848 GSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLrshedtvrlsaekGRLDRTLTGAELELAEAQRQIQQL 1927
Cdd:COG4913    298 EELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRL-------------EQLEREIERLERELEERERRRARL 364

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1928 EAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHRQRVRGLEEQVSTLKGQ 1997
Cdd:COG4913    365 EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 74-445 4.36e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 4.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   74 ASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQTLRLESGELETQEPRGLVRQSVELRR-QLQEEQ 152
Cdd:COG1196    316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELlEALRAA 395

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  153 ASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRNTEHSQDLESALIRLEEEQQRSASL 232
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  233 AQVNAMLREQLDQA---------------------------------------------------GLANQALSEDIRKVT 261
Cdd:COG1196    476 EAALAELLEELAEAaarllllleaeadyegflegvkaalllaglrglagavavligveaayeaalEAALAAALQNIVVED 555

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  262 SDWARSRKELEQREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLG 341
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  342 LSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVERLQKQNLEKDQVNK 421
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715

                          410       420
                   ....*....|....*....|....
gi 1622834689  422 DLTEKLEALESLRLQEQAALETED 445
Cdd:COG1196    716 RLEEELEEEALEEQLEAEREELLE 739
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
156-332 2.64e-53

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 185.24  E-value: 2.64e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  156 RRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRNT-------------EHSQDLESALIRL 222
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELLLRkltleprlqrlerEHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  223 EEEQQRSASLAQVNAMLREQLDQAGLANQALSEDIRKVTSDWARSRKELEQREAAWRREEESFNAYFSNEHSRLLLLWRQ 302
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1622834689  303 VVGFRRLVSEVKMFTERDLLQLGGELARTS 332
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 530-1057 1.71e-27

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 121.97  E-value: 1.71e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  530 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLA 609
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  610 HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREAL 689
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  690 SRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAAL 769
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  770 QGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQE 849
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  850 LEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREH 929
Cdd:COG1196    542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  930 LEAE--GQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWR 1007
Cdd:COG1196    622 LLGRtlVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1008 ELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAE 1057
Cdd:COG1196    702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 613-1433 8.62e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 116.69  E-value: 8.62e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  613 QVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQdgarvrreLERSHRQLEQLEgkRSVLAKELVEVREALSRA 692
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKAER--------YKELKAELRELE--LALLVLRLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  693 TLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGR 772
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  773 QRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQ 852
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  853 ARRAAQRQMEALERAAREKEALAKERAglAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLE- 931
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEr 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  932 --AEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELM--AQKLVQAEREAQASLreqRAAHEEDLQRLQREKEAAWR 1007
Cdd:TIGR02168  483 elAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvLSELISVDEGYEAAI---EAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1008 elEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLL----AESEKQQALS-------LKESEKTALsE 1076
Cdd:TIGR02168  560 --KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkFDPKLRKALSyllggvlVVDDLDNAL-E 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1077 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNAL--TSELRDLRAQLEEavaahaqevrrLQEQAQDLGKQRDSCLR 1154
Cdd:TIGR02168  637 LAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerRREIEELEEKIEE-----------LEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1155 EAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERI 1234
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1235 SLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGE 1314
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1315 RAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAT 1394
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK-RSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 1622834689 1395 RAEAAELGLRlsAAEGRAQGLEAELARVEAQRRAAEAQL 1433
Cdd:TIGR02168  945 LSEEYSLTLE--EAEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 818-1374 1.03e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 116.19  E-value: 1.03e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  818 LEQQLPTLRHERSRlqeqlAQLSRQLSGREQELEQARRAAQRQ--MEALERAAREKEALAKERAGLAVQLAAAEREGRTL 895
Cdd:COG1196    198 LERQLEPLERQAEK-----AERYRELKEELKELEAELLLLKLRelEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  896 SEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKAS--LDKELMAQKL 973
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEelEEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  974 VQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE---------ELLARLEAEKEELSEEIAT 1044
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEleeaeeallERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1045 LQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQL 1124
Cdd:COG1196    433 LEEEEEE-EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1125 EEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKL-----RESQEGREVQRQEAG 1199
Cdd:COG1196    512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratfLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1200 ELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEAR 1279
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1280 RELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEF 1359
Cdd:COG1196    672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                          570
                   ....*....|....*
gi 1622834689 1360 RTRERRLLGSLEEAR 1374
Cdd:COG1196    752 ALEELPEPPDLEELE 766
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1054-1857 3.41e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 3.41e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1054 LLAESEKQQALSLKESEKT----ALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD-RSTVNALTSELRDLRAQLEEAV 1128
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAerykELKAELRELELALLVLRLEELREELEELQEELKEaEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1129 AAHaqevRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEG 1208
Cdd:TIGR02168  274 LEV----SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1209 AKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRR- 1287
Cdd:TIGR02168  350 KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKk 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1288 ----QMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1363
Cdd:TIGR02168  430 leeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1364 RRLLGSLEEA--RGTEKQQLDHARGLELKLEATraeaaeLGLRLSAAEGRaqGLEAELARVEAQR-----RAAEAQLGGL 1436
Cdd:TIGR02168  510 ALLKNQSGLSgiLGVLSELISVDEGYEAAIEAA------LGGRLQAVVVE--NLNAAKKAIAFLKqnelgRVTFLPLDSI 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1437 RSALRRGLGLGRAPS------PAPRPVPGSPARDAAAGGSGDGLSSPSNLECSPGSQPPSPGPATSPAppdLDPETVR-- 1508
Cdd:TIGR02168  582 KGTEIQGNDREILKNiegflgVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVT---LDGDLVRpg 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1509 ----GALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDhatlrarQLQKAVAESEEARRSVDGRLSGVQAEMALQ 1584
Cdd:TIGR02168  659 gvitGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALA-------ELRKELEELEEELEQLRKELEELSRQISAL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1585 EESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSsaslns 1744
Cdd:TIGR02168  812 LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL------ 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1745 tqdknlhlqkaltacEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQE 1824
Cdd:TIGR02168  886 ---------------EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950

                          810       820       830
                   ....*....|....*....|....*....|....
gi 1622834689 1825 GEA-AALHMVQKLQDERRLLQERLGSLQRALAQL 1857
Cdd:TIGR02168  951 LTLeEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 761-1441 2.53e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.52  E-value: 2.53e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  761 QLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLS 840
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  841 RQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQL 920
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  921 AQLEARREHLEAEgqalllaKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQR 1000
Cdd:TIGR02168  396 ASLNNEIERLEAR-------LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELRE 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1001 EKEAAWRELEAERAQLQSQLQREqeELLARLEAEKEELSEEIATLQQERdEGLLLAESEKQQALSLKESEKTALSEKLMG 1080
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQARL--DSLERLQENLEGFSEGVKALLKNQ-SGLSGILGVLSELISVDEGYEAAIEAALGG 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1081 TRHSLATISLEMERQKRDAQSRQEQDRSTVNALTS-------ELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCL 1153
Cdd:TIGR02168  546 RLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSikgteiqGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGV 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1154 REAEELRTQLRLL------------------------------EDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRR 1203
Cdd:TIGR02168  626 LVVDDLDNALELAkklrpgyrivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1204 SLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQ 1283
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1284 ELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKL------QEQEG 1357
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIeslaaeIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1358 EFRTRERRLLGSLEEARGTEKQQLDHARgleLKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLR 1437
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLR---SELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942


                   ....
gi 1622834689 1438 SALR 1441
Cdd:TIGR02168  943 ERLS 946
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 87-944 7.40e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 7.40e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   87 QQELSRVEDLLAQSRAERD------ELAIKYNAVSERLEQ------TLRLESGELETQEPRGLVRQSVELRRQLQEEQAS 154
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKslerqaEKAERYKELKAELRElelallVLRLEELREELEELQEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  155 YRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLL---ERSGELEQQRLRNTEHSQDLESALIRLEEE----QQ 227
Cdd:TIGR02168  265 LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQilrERLANLERQLEELEAQLEELESKLDELAEElaelEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  228 RSASLAQVNAMLREQLDQAGLANQALSEDIRKVTSDWARSRKELEQREaawrREEESFNAYFSNEHSRLlllwrqvvgfR 307
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE----LQIASLNNEIERLEARL----------E 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  308 RLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQ 387
Cdd:TIGR02168  411 RLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  388 SDLDKaDLSARVTELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRlqeqAALETEDGEGLQQTLRDLAQAVLSDSESG 467
Cdd:TIGR02168  491 LDSLE-RLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE----AAIEAALGGRLQAVVVENLNAAKKAIAFL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  468 VQLSgsertadasdgslrglSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIH-SALHKRQLQVQDMRGRYEASQ 546
Cdd:TIGR02168  566 KQNE----------------LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLvKFDPKLRKALSYLLGGVLVVD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  547 DLLGTLRKQLSDSESERRALEEQLQRLRdktdGAMQAQEDAQREVQRLRSANELlsreksnlahslqvaqqqaEELRQER 626
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRP----GGVITGGSAKTNSSILERRREI-------------------EELEEKI 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  627 EKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEV 706
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  707 AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREE 786
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  787 QERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALER 866
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  867 AAREKEALAKERAGLAVQLAA-AEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQL--------------EARREHLE 931
Cdd:TIGR02168  927 LELRLEGLEVRIDNLQERLSEeYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaieeyeelKERYDFLT 1006

                          890
                   ....*....|...
gi 1622834689  932 AEGQALLLAKETL 944
Cdd:TIGR02168 1007 AQKEDLTEAKETL 1019
PTZ00121 PTZ00121
MAEBL; Provisional
 562-1252 6.73e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 87.89  E-value: 6.73e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  562 ERRALEEQLQRLRDKTDGAMQAQEDAqREVQRLRSANELLSREKSNLAHSLQVAQQ--QAEELRQEREKLQAAQEELRRQ 639
Cdd:PTZ00121  1138 DARKAEEARKAEDAKRVEIARKAEDA-RKAEEARKAEDAKKAEAARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEE 1216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  640 RDRLEEEQE-DAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQrdmlqAEKAEVAEALTKAEAGRV 718
Cdd:PTZ00121  1217 ARKAEDAKKaEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIK-----AEEARKADELKKAEEKKK 1291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  719 --ELELSMTKLRAEEASLQ-DSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRL 795
Cdd:PTZ00121  1292 adEAKKAEEKKKADEAKKKaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK 1371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  796 EQEVARQGLEGSLRVAEQAQEVLEQQlptlrhERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALA 875
Cdd:PTZ00121  1372 KKEEAKKKADAAKKKAEEKKKADEAK------KKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKK 1445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  876 KERAGLAVQLAAAEREGRTLSEEATRL-RLEKEALEG-SLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQ 953
Cdd:PTZ00121  1446 ADEAKKKAEEAKKAEEAKKKAEEAKKAdEAKKKAEEAkKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAD 1525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  954 QIIAIQEKASLDKELMAQKLVQAEREAQAslrEQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEA 1033
Cdd:PTZ00121  1526 EAKKAEEAKKADEAKKAEEKKKADELKKA---EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE 1602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1034 EKeelseeiatlQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRhslatislEMERQKRDAQSRQEQDRSTVNAl 1113
Cdd:PTZ00121  1603 EE----------KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKK--------EAEEKKKAEELKKAEEENKIKA- 1663

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1114 tselrDLRAQLEEAVAAHAQEVRRLQEQAQdlgKQRDSCLREAEELRTQlrlledarDGLRRELLEAQRKLRESQEGREV 1193
Cdd:PTZ00121  1664 -----AEEAKKAEEDKKKAEEAKKAEEDEK---KAAEALKKEAEEAKKA--------EELKKKEAEEKKKAEELKKAEEE 1727

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834689 1194 QRQEAGELRRSLGEGAKEREALRRSNEELRaavKKAESERISLKLANEDKEQKLALLEE 1252
Cdd:PTZ00121  1728 NKIKAEEAKKEAEEDKKKAEEAKKDEEEKK---KIAHLKKEEEKKAEEIRKEKEAVIEE 1783
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1654-2011 2.64e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.37  E-value: 2.64e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1654 LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTE 1733
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1734 ALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQ 1813
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1814 QLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSH 1893
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1894 EDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDA-----QQQQHLELQQEVERLRSAQVQ 1968
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkaalLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1622834689 1969 TERTLEARERAHRQRVRGLEEQVSTLKGQLQQELRRSSAPFSP 2011
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLP 578
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 87-704 7.30e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.22  E-value: 7.30e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   87 QQELSRVEDLLAQSRAERDEL------AIKYNAVSERLEQTlrlesgeletqeprgLVRQSVELRRQLQEEQASYRRKLQ 160
Cdd:COG1196    185 EENLERLEDILGELERQLEPLerqaekAERYRELKEELKEL---------------EAELLLLKLRELEAELEELEAELE 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  161 AYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRNTEHSQDLESALIRLEEEQQRSASLAQVNAMLR 240
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  241 EQLDQAGLANQALSEDIRKVTSDWARSRKELEQREAAWRREEESFNAyfsnEHSRLLLLWRQVVGFRRLVSEVKMFTERD 320
Cdd:COG1196    330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE----AEEELEELAEELLEALRAAAELAAQLEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  321 LLQLGGELARTSRAVQEAGLGLSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVT 400
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  401 ELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLqqTLRDLAQAVLSDSESGVQLSGSERTADAS 480
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA--AYEAALEAALAAALQNIVVEDDEVAAAAI 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  481 DGSLRGLSGQRTPSPPRRSSPGRGRSPRRgpspacsdssTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSE 560
Cdd:COG1196    564 EYLKAAKAGRATFLPLDKIRARAALAAAL----------ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  561 SERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQR 640
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834689  641 DRLEEEQEDAVQdgARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 704
Cdd:COG1196    714 EERLEEELEEEA--LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
PTZ00121 PTZ00121
MAEBL; Provisional
 840-1430 2.71e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 82.50  E-value: 2.71e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  840 SRQLSGREQELEQARRAAQRQMEALERAAREKEAlaKERAGLAVQLAAAERegrtlSEEATRLRLEKEALEGSLFEVQRQ 919
Cdd:PTZ00121  1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEA--KKKAEDARKAEEARK-----AEDARKAEEARKAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  920 LAqlEARREHLEAEGQALLLAKETltgelaglrQQIIAIQEKASLDKELMAQKLVQAER-EAQASLREQRAAHEED-LQR 997
Cdd:PTZ00121  1160 AE--DARKAEEARKAEDAKKAEAA---------RKAEEVRKAEELRKAEDARKAEAARKaEEERKAEEARKAEDAKkAEA 1228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  998 LQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEglLLAESEKQQALSLKESEKTALSEK 1077
Cdd:PTZ00121  1229 VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE--LKKAEEKKKADEAKKAEEKKKADE 1306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1078 LMGtrhslatiSLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVA---AHAQEVRRLQEQAQDLGKQRDSCLR 1154
Cdd:PTZ00121  1307 AKK--------KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAeaeAAADEAEAAEEKAEAAEKKKEEAKK 1378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1155 EAEELRTQLRLLEDArDGLRRELLEAQRKLRESQEgREVQRQEAGELRRSLGEGAKEREALRRSNEELRA--AVKKAESE 1232
Cdd:PTZ00121  1379 KADAAKKKAEEKKKA-DEAKKKAEEDKKKADELKK-AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEA 1456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1233 RISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL--AELQGRL 1310
Cdd:PTZ00121  1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkAEEAKKA 1536

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1311 ALGERAEKESRRETLGLRQRLLKGEaslevmrQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELK 1390
Cdd:PTZ00121  1537 DEAKKAEEKKKADELKKAEELKKAE-------EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1622834689 1391 LEATRAEAAEL-GLRLSAAEGRAQGLEAELARVEAQRRAAE 1430
Cdd:PTZ00121  1610 EEAKKAEEAKIkAEELKKAEEEKKKVEQLKKKEAEEKKKAE 1650
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 550-1374 3.52e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 65.38  E-value: 3.52e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  550 GTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQ-------VAQQQAEEL 622
Cdd:pfam02463  142 GKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQakkaleyYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  623 RQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAE 702
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  703 KAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATV 782
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  783 AREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQME 862
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  863 ALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKE 942
Cdd:pfam02463  462 KDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  943 TLTGELAGLRQQIIAIQEKASLDKE--------LMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERA 1014
Cdd:pfam02463  542 KVAISTAVIVEVSATADEVEERQKLvraltelpLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1015 QLQSQLQREQEELLARLEAEKEELSEEIATLQQERdeglLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER 1094
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEE----GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRR 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1095 QKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLR 1174
Cdd:pfam02463  698 QLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1175 RELLEAQRKLRESQEGREVQRQEagELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEAR 1254
Cdd:pfam02463  778 EEREKTEKLKVEEEKEEKLKAQE--EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1255 TAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETlgLRQRLLKG 1334
Cdd:pfam02463  856 LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE--EAEILLKY 933

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1622834689 1335 EASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEAR 1374
Cdd:pfam02463  934 EEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973
PTZ00121 PTZ00121
MAEBL; Provisional
 1207-1995 7.28e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.23  E-value: 7.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1207 EGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARtavgkeagELRTGLQEVERSRLEARRELQELR 1286
Cdd:PTZ00121  1057 EGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAK--------KTETGKAEEARKAEEAKKKAEDAR 1128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1287 RQMKMLDSENTRLGREL--AELQGRLALGERAEKESRRETLGLRQRLLKGEAS---LEVMR-QELQVAQRKLQEQEGEFR 1360
Cdd:PTZ00121  1129 KAEEARKAEDARKAEEArkAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAArkaEEVRKaEELRKAEDARKAEAARKA 1208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1361 TRERRLlgslEEARGTEKQQLDHA--RGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGglrS 1438
Cdd:PTZ00121  1209 EEERKA----EEARKAEDAKKAEAvkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA---D 1281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1439 ALRRGLGLGRAPspaprpvpgspardaaaggsgdglsspsnlECSPGSQPPSPGPATSPAPPDLDPETVRGALQEFLQEL 1518
Cdd:PTZ00121  1282 ELKKAEEKKKAD------------------------------EAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKA 1331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1519 RSAQRERDDLRTQTSAlshQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGrlSGVQAEMALQEESVRRSERERRAT 1598
Cdd:PTZ00121  1332 DAAKKKAEEAKKAAEA---AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA--AKKKAEEKKKADEAKKKAEEDKKK 1406

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1599 LDQIATLERSLQATESELRASQEKiskMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQ 1678
Cdd:PTZ00121  1407 ADELKKAAAAKKKADEAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1679 aqalqdRVDSLQRQVADSEVKAGTLQLTVERLNGA--LAKVEESEGAlrDKVRGLTEALAQSSASLNSTQDKNLHLQKA- 1755
Cdd:PTZ00121  1484 ------KADEAKKKAEEAKKKADEAKKAAEAKKKAdeAKKAEEAKKA--DEAKKAEEAKKADEAKKAEEKKKADELKKAe 1555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1756 -LTACEHDRQVLQ-----ERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAA 1829
Cdd:PTZ00121  1556 eLKKAEEKKKAEEakkaeEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKV 1635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1830 LHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRT 1909
Cdd:PTZ00121  1636 EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK 1715

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1910 LTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHRQRVRGLEE 1989
Cdd:PTZ00121  1716 KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRME 1795


                   ....*.
gi 1622834689 1990 QVSTLK 1995
Cdd:PTZ00121  1796 VDKKIK 1801
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1768-1997 5.84e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 5.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1768 ERLDAARQALSEARkqssslgEQVQTLRgEVADLELQQVEAEGQLQQLREVLRQRQegeaaalhmVQKLQDERRLLQERL 1847
Cdd:COG4913    235 DDLERAHEALEDAR-------EQIELLE-PIRELAERYAAARERLAELEYLRAALR---------LWFAQRRLELLEAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1848 GSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLrshedtvrlsaekGRLDRTLTGAELELAEAQRQIQQL 1927
Cdd:COG4913    298 EELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRL-------------EQLEREIERLERELEERERRRARL 364

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1928 EAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHRQRVRGLEEQVSTLKGQ 1997
Cdd:COG4913    365 EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 74-445 4.36e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 4.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   74 ASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQTLRLESGELETQEPRGLVRQSVELRR-QLQEEQ 152
Cdd:COG1196    316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELlEALRAA 395

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  153 ASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRNTEHSQDLESALIRLEEEQQRSASL 232
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  233 AQVNAMLREQLDQA---------------------------------------------------GLANQALSEDIRKVT 261
Cdd:COG1196    476 EAALAELLEELAEAaarllllleaeadyegflegvkaalllaglrglagavavligveaayeaalEAALAAALQNIVVED 555

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  262 SDWARSRKELEQREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLG 341
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  342 LSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVERLQKQNLEKDQVNK 421
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715

                          410       420
                   ....*....|....*....|....
gi 1622834689  422 DLTEKLEALESLRLQEQAALETED 445
Cdd:COG1196    716 RLEEELEEEALEEQLEAEREELLE 739
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 965-1299 9.38e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.89  E-value: 9.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  965 DKELMAQKLVQAEREAQASLREQRAAHEE-DLQRLQREKEAAWRELEAERAQLQSQLQREQEellarlEAEKEELSEEIA 1043
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKmEQERLRQEKEEKAREVERRRKLEEAEKARQAE------MDRQAAIYAEQE 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1044 TLQQERDEGLLLAESEKQQalslKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDlraq 1123
Cdd:pfam17380  341 RMAMERERELERIRQEERK----RELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQ---- 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1124 leeavaahaqevRRLQEQAQDLGKQRdsclREAEELRT-QLRLLEDARDglrRELLEAQRKLRESQEGREVQRQEAGELR 1202
Cdd:pfam17380  413 ------------RKIQQQKVEMEQIR----AEQEEARQrEVRRLEEERA---REMERVRLEEQERQQQVERLRQQEEERK 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1203 RSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLAL-LEEARTAVGKEAGELRTGLQEVERSRLEARRE 1281
Cdd:pfam17380  474 RKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKeMEERQKAIYEEERRREAEEERRKQQEMEERRR 553

                          330
                   ....*....|....*...
gi 1622834689 1282 LQElrrQMKMLDSENTRL 1299
Cdd:pfam17380  554 IQE---QMRKATEERSRL 568
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 80-630 1.00e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.81  E-value: 1.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   80 QEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQTLRLESGELET--QEPRGLVRQSVELRRQLQEEQASYRR 157
Cdd:pfam15921  309 RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEarTERDQFSQESGNLDDQLQKLLADLHK 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  158 KLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLE--RSGELEQQRLRNTEHSQDLESALIR-----LEEEQQRSA 230
Cdd:pfam15921  389 REKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEvqRLEALLKAMKSECQGQMERQMAAIQgknesLEKVSSLTA 468

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  231 SLAQVNAMLREQLDQAGLANQALSEDIRKVtSDWARSRKELEqreaawrREEESFNAYFSNEHSRLLLLWRQVVGFRRLV 310
Cdd:pfam15921  469 QLESTKEMLRKVVEELTAKKMTLESSERTV-SDLTASLQEKE-------RAIEATNAEITKLRSRVDLKLQELQHLKNEG 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  311 SEVK-MFTERDLLQLggELARTSRAVQEAGLGLSTGLRLA--ESRTEAALEKQallQAQLEEQLRDKVLREKDLAQQQMQ 387
Cdd:pfam15921  541 DHLRnVQTECEALKL--QMAEKDKVIEILRQQIENMTQLVgqHGRTAGAMQVE---KAQLEKEINDRRLELQEFKILKDK 615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  388 SDLDKADLSARVTELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRLQEQAALE--TEDGEGLQQTLRDLAQAV-LSDS 464
Cdd:pfam15921  616 KDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNslSEDYEVLKRNFRNKSEEMeTTTN 695

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  465 ESGVQLSGSERTADASDGSLRGLSGqrtpspprrsspgrgrsprrgpspacSDSSTLALIHSAlhkrQLQVQDMRGRYEA 544
Cdd:pfam15921  696 KLKMQLKSAQSELEQTRNTLKSMEG--------------------------SDGHAMKVAMGM----QKQITAKRGQIDA 745

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  545 SQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNL-----AHSLQVAQQQA 619
Cdd:pfam15921  746 LQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMevaldKASLQFAECQD 825

                          570
                   ....*....|.
gi 1622834689  620 EELRQEREKLQ 630
Cdd:pfam15921  826 IIQRQEQESVR 836
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1511-1850 3.20e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 45.66  E-value: 3.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1511 LQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRR 1590
Cdd:pfam07888   47 LQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAA 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1591 SERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESrtvklelQRRSLEGELQRSRL 1670
Cdd:pfam07888  127 HEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEE-------ELRSLSKEFQELRN 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1671 GLSDREAQAQALQDRVDSL-------QRQVADSEVKAGTLQLTVERLNGALAKVE------ESEGALRDKVRG-LTEALA 1736
Cdd:pfam07888  200 SLAQRDTQVLQLQDTITTLtqklttaHRKEAENEALLEELRSLQERLNASERKVEglgeelSSMAAQRDRTQAeLHQARL 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1737 QSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLE-----------LQQ 1805
Cdd:pfam07888  280 QAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEvelgrekdcnrVQL 359

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1622834689 1806 VEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSL 1850
Cdd:pfam07888  360 SESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETV 404
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 544-859 4.02e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 45.60  E-value: 4.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  544 ASQDLLGTLRKQLSDSESERRALEEQlqrlrdktdgaMQAQEDAQRevqrlrsanelLSREKSNLAHSLQVAQQQAEELR 623
Cdd:NF012221  1539 ESSQQADAVSKHAKQDDAAQNALADK-----------ERAEADRQR-----------LEQEKQQQLAAISGSQSQLESTD 1596

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  624 QereklQAAQEELRRQRDRLEEEQEDavqdgarVRRELERSHRQLEQLEGK-----------RSVLAKELVE-VREALSR 691
Cdd:NF012221  1597 Q-----NALETNGQAQRDAILEESRA-------VTKELTTLAQGLDALDSQatyagesgdqwRNPFAGGLLDrVQEQLDD 1664

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  692 ATLQ--------RDMLQAEKAEVAEALTKAEAGRVELElsmtKLRAEeasLQDSLSKLSALNESLAQDKLDlNRLVAQLE 763
Cdd:NF012221  1665 AKKIsgkqladaKQRHVDNQQKVKDAVAKSEAGVAQGE----QNQAN---AEQDIDDAKADAEKRKDDALA-KQNEAQQA 1736

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  764 EEKA--ALQGRQRQAEQEATVAREEQERLEELRLEQEVA------RQGLEGSlRVAEQAQEVlEQQLPTLRHERSRLQEQ 835
Cdd:NF012221  1737 ESDAnaAANDAQSRGEQDASAAENKANQAQADAKGAKQDesdkpnRQGAAGS-GLSGKAYSV-EGVAEPGSHINPDSPAA 1814

                          330       340
                   ....*....|....*....|....*.
gi 1622834689  836 L-AQLSRQLSGREQE-LEQARRAAQR 859
Cdd:NF012221  1815 AdGRFSEGLTEQEQEaLEGATNAVNR 1840
PTZ00121 PTZ00121
MAEBL; Provisional
 88-766 4.45e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 4.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   88 QELSRVEDLLAQSRAERDELAiKYNAVSERLEQTLRLE-SGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQ 166
Cdd:PTZ00121  1131 EEARKAEDARKAEEARKAEDA-KRVEIARKAEDARKAEeARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAE 1209

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  167 Q-RQAQLVQRLQ-GKILQYKKRCSELEQQLLERSgelEQQRLRNTEHSQDLESAliRLEEEQQRSASLAQVNAMLREQLD 244
Cdd:PTZ00121  1210 EeRKAEEARKAEdAKKAEAVKKAEEAKKDAEEAK---KAEEERNNEEIRKFEEA--RMAHFARRQAAIKAEEARKADELK 1284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  245 QAglanqalsEDIRKvtSDWARSRKELEQREAAWRREEESfnayfsnehsrllllwRQVVGFRRLVSEVKMFTErDLLQL 324
Cdd:PTZ00121  1285 KA--------EEKKK--ADEAKKAEEKKKADEAKKKAEEA----------------KKADEAKKKAEEAKKKAD-AAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  325 GGELARTSRAVQEAGLGLSTGLRLAESRTEAALEKQALLQAQLEE-QLRDKVLREKDLAQQQMQSDLDKADLSARVTELG 403
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAaKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  404 LAVERLQKQNLEK---DQVNKDLTEKLEALESLRLQEQA---------ALETEDGEGLQQTLRDLAQAVLSDSESGVQLS 471
Cdd:PTZ00121  1418 KKADEAKKKAEEKkkaDEAKKKAEEAKKADEAKKKAEEAkkaeeakkkAEEAKKADEAKKKAEEAKKADEAKKKAEEAKK 1497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  472 GSERTADASDGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLA--LIHSALHKRQLQVQDMRGRYEASQDLL 549
Cdd:PTZ00121  1498 KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAdeLKKAEELKKAEEKKKAEEAKKAEEDKN 1577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  550 GTLRKQLSDSESERRALEEQLQRLRD-KTDGAMQAQ--EDAQREVQRLRSANELlSREKSNLAHSLQVAQQQAEELRQER 626
Cdd:PTZ00121  1578 MALRKAEEAKKAEEARIEEVMKLYEEeKKMKAEEAKkaEEAKIKAEELKKAEEE-KKKVEQLKKKEAEEKKKAEELKKAE 1656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  627 EKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREA--LSRATLQRDMLQAE-K 703
Cdd:PTZ00121  1657 EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAeeLKKAEEENKIKAEEaK 1736

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622834689  704 AEVAEALTKAEAGRVElELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 766
Cdd:PTZ00121  1737 KEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
156-332 2.64e-53

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 185.24  E-value: 2.64e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  156 RRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRNT-------------EHSQDLESALIRL 222
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELLLRkltleprlqrlerEHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  223 EEEQQRSASLAQVNAMLREQLDQAGLANQALSEDIRKVTSDWARSRKELEQREAAWRREEESFNAYFSNEHSRLLLLWRQ 302
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 1622834689  303 VVGFRRLVSEVKMFTERDLLQLGGELARTS 332
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 530-1057 1.71e-27

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 121.97  E-value: 1.71e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  530 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLA 609
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  610 HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREAL 689
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  690 SRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAAL 769
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  770 QGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQE 849
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  850 LEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREH 929
Cdd:COG1196    542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  930 LEAE--GQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWR 1007
Cdd:COG1196    622 LLGRtlVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1008 ELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAE 1057
Cdd:COG1196    702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 613-1433 8.62e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 116.69  E-value: 8.62e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  613 QVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQdgarvrreLERSHRQLEQLEgkRSVLAKELVEVREALSRA 692
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKAER--------YKELKAELRELE--LALLVLRLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  693 TLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGR 772
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  773 QRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQ 852
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  853 ARRAAQRQMEALERAAREKEALAKERAglAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLE- 931
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEr 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  932 --AEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELM--AQKLVQAEREAQASLreqRAAHEEDLQRLQREKEAAWR 1007
Cdd:TIGR02168  483 elAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvLSELISVDEGYEAAI---EAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1008 elEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLL----AESEKQQALS-------LKESEKTALsE 1076
Cdd:TIGR02168  560 --KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkFDPKLRKALSyllggvlVVDDLDNAL-E 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1077 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNAL--TSELRDLRAQLEEavaahaqevrrLQEQAQDLGKQRDSCLR 1154
Cdd:TIGR02168  637 LAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerRREIEELEEKIEE-----------LEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1155 EAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERI 1234
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1235 SLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGE 1314
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1315 RAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAT 1394
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK-RSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 1622834689 1395 RAEAAELGLRlsAAEGRAQGLEAELARVEAQRRAAEAQL 1433
Cdd:TIGR02168  945 LSEEYSLTLE--EAEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 818-1374 1.03e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 116.19  E-value: 1.03e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  818 LEQQLPTLRHERSRlqeqlAQLSRQLSGREQELEQARRAAQRQ--MEALERAAREKEALAKERAGLAVQLAAAEREGRTL 895
Cdd:COG1196    198 LERQLEPLERQAEK-----AERYRELKEELKELEAELLLLKLRelEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  896 SEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKAS--LDKELMAQKL 973
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEelEEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  974 VQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE---------ELLARLEAEKEELSEEIAT 1044
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEleeaeeallERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1045 LQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQL 1124
Cdd:COG1196    433 LEEEEEE-EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1125 EEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKL-----RESQEGREVQRQEAG 1199
Cdd:COG1196    512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratfLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1200 ELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEAR 1279
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1280 RELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEF 1359
Cdd:COG1196    672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                          570
                   ....*....|....*
gi 1622834689 1360 RTRERRLLGSLEEAR 1374
Cdd:COG1196    752 ALEELPEPPDLEELE 766
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 563-1354 2.40e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 115.15  E-value: 2.40e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  563 RRALEEQLQRLRDKTDGAMQAQE--DAQREVQRLRSANELLS--REKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRR 638
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKElkAELRELELALLVLRLEElrEELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  639 QRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRV 718
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  719 ELELSMTKLRAEeasLQDSLSKLSALNESLaqdkLDLNRLVAQLEEEKAALQGRQRQAEQ-----EATVAREEQERLEEL 793
Cdd:TIGR02168  355 SLEAELEELEAE---LEELESRLEELEEQL----ETLRSKVAQLELQIASLNNEIERLEArlerlEDRRERLQQEIEELL 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  794 RLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQAR---RAAQRQMEALERAARE 870
Cdd:TIGR02168  428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEG 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  871 KEALAKERAGL-------------------AVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLE 931
Cdd:TIGR02168  508 VKALLKNQSGLsgilgvlselisvdegyeaAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQ 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  932 AEGQALLLAKETLTGELAGLRQQIIAIQEKAS--LDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQRekeaaWREL 1009
Cdd:TIGR02168  588 GNDREILKNIEGFLGVAKDLVKFDPKLRKALSylLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPG-----GVIT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1010 EAERAQLQSQLQREQEellarleaekeelseeIATLQQERDEgLLLAESEKQQALSLKESEKTALSEKLmgtrHSLATIS 1089
Cdd:TIGR02168  663 GGSAKTNSSILERRRE----------------IEELEEKIEE-LEEKIAELEKALAELRKELEELEEEL----EQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1090 LEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAvaahAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDA 1169
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL----EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1170 RDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLAL 1249
Cdd:TIGR02168  798 LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1250 LEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLA-LGERAEKESRRETLGLR 1328
Cdd:TIGR02168  878 LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDnLQERLSEEYSLTLEEAE 957

                          810       820
                   ....*....|....*....|....*.
gi 1622834689 1329 QRLLKGEASLEVMRQELQVAQRKLQE 1354
Cdd:TIGR02168  958 ALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 530-1310 9.72e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.23  E-value: 9.72e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  530 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLA 609
Cdd:TIGR02168  222 LRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  610 HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQedavqdgARVRRELErshRQLEQLEGKRSVLAKELVEVREAL 689
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELESKLDELAEEL-------AELEEKLE---ELKEELESLEAELEELEAELEELE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  690 SRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLA-QDKLDLNRLVAQLEEEKAA 768
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEeAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  769 LQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLE---QQLPTLRHERSRLQEQLAQLSRQLSG 845
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsEGVKALLKNQSGLSGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  846 REqELEQARRAAQRQ------MEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQ 919
Cdd:TIGR02168  532 DE-GYEAAIEAALGGrlqavvVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  920 LAQLEARREHL-------EAEGQALLLAKE--------TLTGELA--------GLRQQIIAIQEKASLDKELMAQKLVQA 976
Cdd:TIGR02168  611 DPKLRKALSYLlggvlvvDDLDNALELAKKlrpgyrivTLDGDLVrpggvitgGSAKTNSSILERRREIEELEEKIEELE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  977 EREAQasLREQRAAHEEDLQRLQREKEAAWRELEAERAQLqsqlqREQEELLARLEAEKEELSEEIATLQQERDEglLLA 1056
Cdd:TIGR02168  691 EKIAE--LEKALAELRKELEELEEELEQLRKELEELSRQI-----SALRKDLARLEAEVEQLEERIAQLSKELTE--LEA 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1057 ESEKQQALSLKESEKTALSEKLMGTRhslatislemERQKRDAQSRQEQDRSTVNALTSELRDLR---AQLEEAVAAHAQ 1133
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIEEL----------EAQIEQLKEELKALREALDELRAELTLLNeeaANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1134 EVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKERE 1213
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1214 ALRRSNEELRAAVKKAESERISLKLanedkeQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLD 1293
Cdd:TIGR02168  912 ELRRELEELREKLAQLELRLEGLEV------RIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985

                          810
                   ....*....|....*..
gi 1622834689 1294 SENTRLGRELAELQGRL 1310
Cdd:TIGR02168  986 PVNLAAIEEYEELKERY 1002
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 634-1233 1.03e-24

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 113.11  E-value: 1.03e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  634 EELRRQRDRLEEEQEDAVQdGARVRRELERshRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 713
Cdd:COG1196    196 GELERQLEPLERQAEKAER-YRELKEELKE--LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  714 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEatvareeqerLEEL 793
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE----------LEEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  794 RLEQEVA---RQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAARE 870
Cdd:COG1196    343 EEELEEAeeeLEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  871 KEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAG 950
Cdd:COG1196    423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  951 LRQQIIAIQEKASLDKELMAQKLVQAEREAQAslREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELlaR 1030
Cdd:COG1196    503 YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA--AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL--P 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1031 LEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTV 1110
Cdd:COG1196    579 LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1111 NALTSELRDLRAQLEEAVAAhaqevRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEG 1190
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAE-----AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1622834689 1191 REVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESER 1233
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 546-1147 4.22e-24

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 110.80  E-value: 4.22e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  546 QDLLGTLRKQLSDSESERRALEE--QLQRLRDKTDGAMQAQEDAQREVQRlrsanELLSREKSNLAHSLQVAQQQAEELR 623
Cdd:COG1196    192 EDILGELERQLEPLERQAEKAERyrELKEELKELEAELLLLKLRELEAEL-----EELEAELEELEAELEELEAELAELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  624 QEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEK 703
Cdd:COG1196    267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  704 AEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVA 783
Cdd:COG1196    347 EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  784 REEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLsGREQELEQARRAAQRQMEA 863
Cdd:COG1196    427 EEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL-AEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  864 LERAAREKEALAKERagLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKET 943
Cdd:COG1196    506 FLEGVKAALLLAGLR--GLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  944 LTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 1023
Cdd:COG1196    584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1024 QEELLARLEAEKEelseeiATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQ 1103
Cdd:COG1196    664 GGSRRELLAALLE------AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1622834689 1104 EQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGK 1147
Cdd:COG1196    738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1054-1857 3.41e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 3.41e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1054 LLAESEKQQALSLKESEKT----ALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD-RSTVNALTSELRDLRAQLEEAV 1128
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAerykELKAELRELELALLVLRLEELREELEELQEELKEaEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1129 AAHaqevRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEG 1208
Cdd:TIGR02168  274 LEV----SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1209 AKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRR- 1287
Cdd:TIGR02168  350 KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKk 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1288 ----QMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1363
Cdd:TIGR02168  430 leeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1364 RRLLGSLEEA--RGTEKQQLDHARGLELKLEATraeaaeLGLRLSAAEGRaqGLEAELARVEAQR-----RAAEAQLGGL 1436
Cdd:TIGR02168  510 ALLKNQSGLSgiLGVLSELISVDEGYEAAIEAA------LGGRLQAVVVE--NLNAAKKAIAFLKqnelgRVTFLPLDSI 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1437 RSALRRGLGLGRAPS------PAPRPVPGSPARDAAAGGSGDGLSSPSNLECSPGSQPPSPGPATSPAppdLDPETVR-- 1508
Cdd:TIGR02168  582 KGTEIQGNDREILKNiegflgVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVT---LDGDLVRpg 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1509 ----GALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDhatlrarQLQKAVAESEEARRSVDGRLSGVQAEMALQ 1584
Cdd:TIGR02168  659 gvitGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALA-------ELRKELEELEEELEQLRKELEELSRQISAL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1585 EESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSsaslns 1744
Cdd:TIGR02168  812 LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL------ 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1745 tqdknlhlqkaltacEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQE 1824
Cdd:TIGR02168  886 ---------------EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950

                          810       820       830
                   ....*....|....*....|....*....|....
gi 1622834689 1825 GEA-AALHMVQKLQDERRLLQERLGSLQRALAQL 1857
Cdd:TIGR02168  951 LTLeEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1116-1927 1.03e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 106.68  E-value: 1.03e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1116 ELRDLRAQLEEA-VAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQ 1194
Cdd:TIGR02168  214 RYKELKAELRELeLALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1195 RQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERS 1274
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1275 RLEARRELQELRRqmkmldsentrlGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQvAQRKLQE 1354
Cdd:TIGR02168  374 LEELEEQLETLRS------------KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA-ELKELQA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1355 QEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAE---GRAQGLEAELARVEAQRRAAEA 1431
Cdd:TIGR02168  441 ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLErlqENLEGFSEGVKALLKNQSGLSG 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1432 QLGGLRSALRRGLGLGRApspaprpvpgspaRDAAAGGSGDGL---SSPSNLECSPGSQPPSPGPATSPAPPDLDPETVR 1508
Cdd:TIGR02168  521 ILGVLSELISVDEGYEAA-------------IEAALGGRLQAVvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQ 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1509 GALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARR-SVDGRLSGVQAEMALQEES 1587
Cdd:TIGR02168  588 GNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIvTLDGDLVRPGGVITGGSAK 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1588 VRRsererratldqiatlerSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQR 1667
Cdd:TIGR02168  668 TNS-----------------SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1668 SRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQD 1747
Cdd:TIGR02168  731 LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1748 KNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEA 1827
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1828 AALHMVQKLQDERRLLQERLGSLQRALAQLEAekrEVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEkgrLD 1907
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSELRRELEELRE---KLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENK---IE 964

                          810       820
                   ....*....|....*....|
gi 1622834689 1908 RTLTGAELELAEAQRQIQQL 1927
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 761-1441 2.53e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.52  E-value: 2.53e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  761 QLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLS 840
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  841 RQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQL 920
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  921 AQLEARREHLEAEgqalllaKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQR 1000
Cdd:TIGR02168  396 ASLNNEIERLEAR-------LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELRE 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1001 EKEAAWRELEAERAQLQSQLQREqeELLARLEAEKEELSEEIATLQQERdEGLLLAESEKQQALSLKESEKTALSEKLMG 1080
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQARL--DSLERLQENLEGFSEGVKALLKNQ-SGLSGILGVLSELISVDEGYEAAIEAALGG 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1081 TRHSLATISLEMERQKRDAQSRQEQDRSTVNALTS-------ELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCL 1153
Cdd:TIGR02168  546 RLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSikgteiqGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGV 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1154 REAEELRTQLRLL------------------------------EDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRR 1203
Cdd:TIGR02168  626 LVVDDLDNALELAkklrpgyrivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1204 SLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQ 1283
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1284 ELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKL------QEQEG 1357
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIeslaaeIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1358 EFRTRERRLLGSLEEARGTEKQQLDHARgleLKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLR 1437
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLR---SELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942


                   ....
gi 1622834689 1438 SALR 1441
Cdd:TIGR02168  943 ERLS 946
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1060-1618 5.41e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 104.25  E-value: 5.41e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1060 KQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHA---QEVR 1136
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArleQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1137 RLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALR 1216
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1217 RSNEELRAAVKKAESERISLKLANEDKEQKLALLEEartavgkEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSEN 1296
Cdd:COG1196    386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEE-------ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1297 TRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGT 1376
Cdd:COG1196    459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1377 EKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLeaELARVEAQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRP 1456
Cdd:COG1196    539 ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL--PLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1457 VPGSPARDAAAGGSGDGLSSPSNLECSPGSQPPSPGPATSPAPPDLDPETVRGALQEFLQELRSAQRERDDLRTQTSALS 1536
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1537 HQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESEL 1616
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776


                   ..
gi 1622834689 1617 RA 1618
Cdd:COG1196    777 EA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 992-1758 2.80e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.59  E-value: 2.80e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  992 EEDLQRLQREKEAA--WRELEAERAQLQSQLQ----REQEELLARLEAEKEELSEEIATLQQErdeglllaESEKQQALS 1065
Cdd:TIGR02168  199 ERQLKSLERQAEKAerYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTAE--------LQELEEKLE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1066 LKESEKTALSEK---LMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAvaahAQEVRRLQEQA 1142
Cdd:TIGR02168  271 ELRLEVSELEEEieeLQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL----AEELAELEEKL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1143 QDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEEL 1222
Cdd:TIGR02168  347 EELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEEL 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1223 RAAVKKAESERISLKLANEDKEQKLALLEEARtavgkeageLRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRE 1302
Cdd:TIGR02168  427 LKKLEEAELKELQAELEELEEELEELQEELER---------LEEALEELREELEEAEQALDAAERELAQLQARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1303 LAELQGrLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRK-LQEQEGEFRTRERRLLGSLEEARgtekqqL 1381
Cdd:TIGR02168  498 QENLEG-FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGrLQAVVVENLNAAKKAIAFLKQNE------L 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1382 DHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPVPGSP 1461
Cdd:TIGR02168  571 GRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1462 ARD------AAAGGSGDGLSSPSNLECSPGSQPPSPGPATSPAPPDLDP-ETVRGALQEFLQELRSAQRERDDLRTQTSA 1534
Cdd:TIGR02168  651 DGDlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKAlAELRKELEELEEELEQLRKELEELSRQISA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1535 LSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERerratldQIATLERSLQATES 1614
Cdd:TIGR02168  731 LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA-------QIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1615 ELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVA 1694
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834689 1695 DSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTA 1758
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE 947
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1179-1998 3.12e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.59  E-value: 3.12e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1179 EAQRKLRESQEGREVQRQEAGELRR---SLGEGAKEREALRRSNEELRAAvkkaesERISLKLANEDKEQKLALLEEART 1255
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERqlkSLERQAEKAERYKELKAELREL------ELALLVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1256 AVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGE 1335
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1336 ASLEVMRQELQVAQRKLQEQEGEFRtrerRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGL 1415
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELE----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1416 EAELARVEAQRRAAEAQLGGLRSALRRglglgrapspaprpvpgsPARDAAAGGSGDGLSSPSNLECSPgsqppspgpat 1495
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKLEE------------------AELKELQAELEELEEELEELQEEL----------- 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1496 spappdldpETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLqKAVAESEEARRSVDGRLS 1575
Cdd:TIGR02168  457 ---------ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV-KALLKNQSGLSGILGVLS 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1576 ---------GVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDA 1646
Cdd:TIGR02168  527 elisvdegyEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1647 SESRTVKLelqRRSLEGELQRSRLglSDREAQAQALQDRVDSLQRQVadseVKAGTLQLTVERLNGALAKVEESEGALRD 1726
Cdd:TIGR02168  607 LVKFDPKL---RKALSYLLGGVLV--VDDLDNALELAKKLRPGYRIV----TLDGDLVRPGGVITGGSAKTNSSILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1727 KVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQV 1806
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1807 EAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVE 1886
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1887 REKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRsaq 1966
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELR--- 914

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1622834689 1967 vQTERTLEARERAHRQRVRGLEEQVSTLKGQL 1998
Cdd:TIGR02168  915 -RELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 87-944 7.40e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 7.40e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   87 QQELSRVEDLLAQSRAERD------ELAIKYNAVSERLEQ------TLRLESGELETQEPRGLVRQSVELRRQLQEEQAS 154
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKslerqaEKAERYKELKAELRElelallVLRLEELREELEELQEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  155 YRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLL---ERSGELEQQRLRNTEHSQDLESALIRLEEE----QQ 227
Cdd:TIGR02168  265 LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQilrERLANLERQLEELEAQLEELESKLDELAEElaelEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  228 RSASLAQVNAMLREQLDQAGLANQALSEDIRKVTSDWARSRKELEQREaawrREEESFNAYFSNEHSRLlllwrqvvgfR 307
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE----LQIASLNNEIERLEARL----------E 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  308 RLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQ 387
Cdd:TIGR02168  411 RLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  388 SDLDKaDLSARVTELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRlqeqAALETEDGEGLQQTLRDLAQAVLSDSESG 467
Cdd:TIGR02168  491 LDSLE-RLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE----AAIEAALGGRLQAVVVENLNAAKKAIAFL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  468 VQLSgsertadasdgslrglSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIH-SALHKRQLQVQDMRGRYEASQ 546
Cdd:TIGR02168  566 KQNE----------------LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLvKFDPKLRKALSYLLGGVLVVD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  547 DLLGTLRKQLSDSESERRALEEQLQRLRdktdGAMQAQEDAQREVQRLRSANELlsreksnlahslqvaqqqaEELRQER 626
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRP----GGVITGGSAKTNSSILERRREI-------------------EELEEKI 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  627 EKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEV 706
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  707 AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREE 786
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  787 QERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALER 866
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  867 AAREKEALAKERAGLAVQLAA-AEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQL--------------EARREHLE 931
Cdd:TIGR02168  927 LELRLEGLEVRIDNLQERLSEeYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaieeyeelKERYDFLT 1006

                          890
                   ....*....|...
gi 1622834689  932 AEGQALLLAKETL 944
Cdd:TIGR02168 1007 AQKEDLTEAKETL 1019
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1093-1694 2.03e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 92.31  E-value: 2.03e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1093 ERQKRDAQS----RQEQDRSTVNALTSELRDLRAQLEEA---VAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRL 1165
Cdd:COG1196    206 ERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELeaeLEELEAELEELEAELAELEAELEELRLELEELELELEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1166 LEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQ 1245
Cdd:COG1196    286 AQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1246 KLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETL 1325
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1326 GLRQRLLKGEASLEVMRQELQVAQRKLQEQEgefrTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRL 1405
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLE----AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1406 SAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRRGLGLGRApspaprpvpgspARDAAAGgsgdglsspsnlecspg 1485
Cdd:COG1196    522 LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY------------LKAAKAG----------------- 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1486 sQPPSPGPATSPAPPDLDPETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEE 1565
Cdd:COG1196    573 -RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1566 ARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLD 1645
Cdd:COG1196    652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 1622834689 1646 ASESRTVKLELQrrsLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVA 1694
Cdd:COG1196    732 AEREELLEELLE---EEELLEEEALEELPEPPDLEELERELERLEREIE 777
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 959-1442 6.90e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.77  E-value: 6.90e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  959 QEKASLDKELMAQKLVQAERE---AQASLREQRAAHEEdLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEK 1035
Cdd:COG1196    220 EELKELEAELLLLKLRELEAEleeLEAELEELEAELEE-LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1036 EELSEEIatLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMErQKRDAQSRQEQDRSTVNALTS 1115
Cdd:COG1196    299 RLEQDIA--RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE-EAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1116 ELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQR 1195
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1196 QEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQK----LALLEEARTAVGKEAGELRTGLQEV 1271
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFlegvKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1272 ERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRqelqvaqrk 1351
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS--------- 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1352 LQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEA 1431
Cdd:COG1196    607 DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686

                          490
                   ....*....|.
gi 1622834689 1432 QLGGLRSALRR 1442
Cdd:COG1196    687 RLAEEELELEE 697
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 617-1383 1.37e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 89.74  E-value: 1.37e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  617 QQAEELRQEREKLQAAQEELRRQRDR----LEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRA 692
Cdd:TIGR02169  198 QQLERLRREREKAERYQALLKEKREYegyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  693 TLQRDML--------QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEE 764
Cdd:TIGR02169  278 NKKIKDLgeeeqlrvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  765 EKAALQGRQRQAEQEAtvareeqerleelrleqevarQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLS 844
Cdd:TIGR02169  358 EYAELKEELEDLRAEL---------------------EEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQ 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  845 GREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE 924
Cdd:TIGR02169  417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAE 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  925 ARREHLEAEGQALLLAKETLTGELAGL-----------RQQIIAIQEKAS-------LDKELMAQKLVQAEREAQAS--- 983
Cdd:TIGR02169  497 AQARASEERVRGGRAVEEVLKASIQGVhgtvaqlgsvgERYATAIEVAAGnrlnnvvVEDDAVAKEAIELLKRRKAGrat 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  984 ---LREQRAAHEE--------------DLQRLQREKEAAWRELeaeraqLQSQLQREQEELLARLeaekeELSEEIATLq 1046
Cdd:TIGR02169  577 flpLNKMRDERRDlsilsedgvigfavDLVEFDPKYEPAFKYV------FGDTLVVEDIEAARRL-----MGKYRMVTL- 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1047 qerdEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEE 1126
Cdd:TIGR02169  645 ----EGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1127 avaahaqevrrLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLG 1206
Cdd:TIGR02169  721 -----------IEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1207 EgaKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARtavgkeagelrtglqeversrlearrelQELR 1286
Cdd:TIGR02169  790 H--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI----------------------------QELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1287 RQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEfRTRERRL 1366
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ-IEKKRKR 918

                          810
                   ....*....|....*..
gi 1622834689 1367 LGSLEEARGTEKQQLDH 1383
Cdd:TIGR02169  919 LSELKAKLEALEEELSE 935
PTZ00121 PTZ00121
MAEBL; Provisional
 562-1252 6.73e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 87.89  E-value: 6.73e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  562 ERRALEEQLQRLRDKTDGAMQAQEDAqREVQRLRSANELLSREKSNLAHSLQVAQQ--QAEELRQEREKLQAAQEELRRQ 639
Cdd:PTZ00121  1138 DARKAEEARKAEDAKRVEIARKAEDA-RKAEEARKAEDAKKAEAARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEE 1216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  640 RDRLEEEQE-DAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQrdmlqAEKAEVAEALTKAEAGRV 718
Cdd:PTZ00121  1217 ARKAEDAKKaEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIK-----AEEARKADELKKAEEKKK 1291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  719 --ELELSMTKLRAEEASLQ-DSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRL 795
Cdd:PTZ00121  1292 adEAKKAEEKKKADEAKKKaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK 1371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  796 EQEVARQGLEGSLRVAEQAQEVLEQQlptlrhERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALA 875
Cdd:PTZ00121  1372 KKEEAKKKADAAKKKAEEKKKADEAK------KKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKK 1445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  876 KERAGLAVQLAAAEREGRTLSEEATRL-RLEKEALEG-SLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQ 953
Cdd:PTZ00121  1446 ADEAKKKAEEAKKAEEAKKKAEEAKKAdEAKKKAEEAkKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAD 1525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  954 QIIAIQEKASLDKELMAQKLVQAEREAQAslrEQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEA 1033
Cdd:PTZ00121  1526 EAKKAEEAKKADEAKKAEEKKKADELKKA---EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE 1602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1034 EKeelseeiatlQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRhslatislEMERQKRDAQSRQEQDRSTVNAl 1113
Cdd:PTZ00121  1603 EE----------KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKK--------EAEEKKKAEELKKAEEENKIKA- 1663

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1114 tselrDLRAQLEEAVAAHAQEVRRLQEQAQdlgKQRDSCLREAEELRTQlrlledarDGLRRELLEAQRKLRESQEGREV 1193
Cdd:PTZ00121  1664 -----AEEAKKAEEDKKKAEEAKKAEEDEK---KAAEALKKEAEEAKKA--------EELKKKEAEEKKKAEELKKAEEE 1727

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834689 1194 QRQEAGELRRSLGEGAKEREALRRSNEELRaavKKAESERISLKLANEDKEQKLALLEE 1252
Cdd:PTZ00121  1728 NKIKAEEAKKEAEEDKKKAEEAKKDEEEKK---KIAHLKKEEEKKAEEIRKEKEAVIEE 1783
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1654-2011 2.64e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.37  E-value: 2.64e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1654 LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTE 1733
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1734 ALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQ 1813
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1814 QLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSH 1893
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1894 EDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDA-----QQQQHLELQQEVERLRSAQVQ 1968
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkaalLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1622834689 1969 TERTLEARERAHRQRVRGLEEQVSTLKGQLQQELRRSSAPFSP 2011
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLP 578
PTZ00121 PTZ00121
MAEBL; Provisional
 597-1281 6.16e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.81  E-value: 6.16e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  597 ANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQ-----EELRRQRD--RLEEE---QEDAVQDGARVRRELERSHR 666
Cdd:PTZ00121  1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEdarkaEEARKAEDarKAEEArkaEDAKRVEIARKAEDARKAEE 1168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  667 QLEQLEGKRSVLAKELVEVREAlsratlqRDMLQAEKAEVAEALTKAEAGRvelelsmtklRAEEASLQDSLSKLSALNE 746
Cdd:PTZ00121  1169 ARKAEDAKKAEAARKAEEVRKA-------EELRKAEDARKAEAARKAEEER----------KAEEARKAEDAKKAEAVKK 1231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  747 SLAQDKldlnrlvaQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEgsLRVAEQAQEVLEQQlptlR 826
Cdd:PTZ00121  1232 AEEAKK--------DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE--LKKAEEKKKADEAK----K 1297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  827 HERSRLQEQL---AQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLR 903
Cdd:PTZ00121  1298 AEEKKKADEAkkkAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAK 1377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  904 LEKEALEGSLFEVQRQLaqlEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKElMAQKLVQAErEAQAS 983
Cdd:PTZ00121  1378 KKADAAKKKAEEKKKAD---EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK-KAEEAKKAD-EAKKK 1452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  984 LREQRAAhEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELL-----ARLEAEKEELSEEIATLQQERDEGLLLAES 1058
Cdd:PTZ00121  1453 AEEAKKA-EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKkkadeAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1059 EKQQALSLKESEKTALSEKLMGTRHslatISLEMERQKRDAQSRQEQDRSTVNALTSELRDL------------------ 1120
Cdd:PTZ00121  1532 EAKKADEAKKAEEKKKADELKKAEE----LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAeearieevmklyeeekkm 1607

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1121 ---RAQLEEAVAAHAQEVRRLQE---QAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQ 1194
Cdd:PTZ00121  1608 kaeEAKKAEEAKIKAEELKKAEEekkKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1195 RQEAGELRRSLGEGAKEREALRRSNEELRAA--VKKAESER-ISLKLANEDKEQKLALLEEARTAVGkEAGELRTGLQEV 1271
Cdd:PTZ00121  1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAeeLKKAEEENkIKAEEAKKEAEEDKKKAEEAKKDEE-EKKKIAHLKKEE 1766

                          730
                   ....*....|
gi 1622834689 1272 ERSRLEARRE 1281
Cdd:PTZ00121  1767 EKKAEEIRKE 1776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 521-1255 6.98e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 84.35  E-value: 6.98e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  521 LALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESER--------RALEEQLQRLRDKTDGAMQAQEDAQREVQ 592
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEqlrvkekiGELEAEIASLERSIAEKERELEDAEERLA 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  593 RLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLE 672
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELK 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  673 GKRSVLAKELVEVREALsratlqrdmlqaekAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDK 752
Cdd:TIGR02169  406 RELDRLQEELQRLSEEL--------------ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  753 LDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSL----RVAEQAQEVLEQQLPTLRHE 828
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVaqlgSVGERYATAIEVAAGNRLNN 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  829 RSRLQEQLAQLSRQLSGREQeleqARRAAQRQMEALERAAREKEALAKERA-GLAVQLAAAERE---------GRTLS-- 896
Cdd:TIGR02169  552 VVVEDDAVAKEAIELLKRRK----AGRATFLPLNKMRDERRDLSILSEDGViGFAVDLVEFDPKyepafkyvfGDTLVve 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  897 --EEATRL--RLEKEALEGSLFEVQ-------RQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASld 965
Cdd:TIGR02169  628 diEAARRLmgKYRMVTLEGELFEKSgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLD-- 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  966 kelmaqKLVQAEREAQASLREQraahEEDLQRLQREKEAAWRELEAERAQLQSqLQREQEELLARLEAEKEELSEEIATL 1045
Cdd:TIGR02169  706 ------ELSQELSDASRKIGEI----EKEIEQLEQEEEKLKERLEELEEDLSS-LEQEIENVKSELKELEARIEELEEDL 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1046 QQERDEgllLAESEKQQALSlKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLE 1125
Cdd:TIGR02169  775 HKLEEA---LNDLEARLSHS-RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK 850

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1126 EavaahaqevrrLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSL 1205
Cdd:TIGR02169  851 S-----------IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1206 GEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEART 1255
Cdd:TIGR02169  920 SELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRA 969
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 87-704 7.30e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.22  E-value: 7.30e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   87 QQELSRVEDLLAQSRAERDEL------AIKYNAVSERLEQTlrlesgeletqeprgLVRQSVELRRQLQEEQASYRRKLQ 160
Cdd:COG1196    185 EENLERLEDILGELERQLEPLerqaekAERYRELKEELKEL---------------EAELLLLKLRELEAELEELEAELE 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  161 AYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRNTEHSQDLESALIRLEEEQQRSASLAQVNAMLR 240
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  241 EQLDQAGLANQALSEDIRKVTSDWARSRKELEQREAAWRREEESFNAyfsnEHSRLLLLWRQVVGFRRLVSEVKMFTERD 320
Cdd:COG1196    330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE----AEEELEELAEELLEALRAAAELAAQLEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  321 LLQLGGELARTSRAVQEAGLGLSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVT 400
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  401 ELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLqqTLRDLAQAVLSDSESGVQLSGSERTADAS 480
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA--AYEAALEAALAAALQNIVVEDDEVAAAAI 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  481 DGSLRGLSGQRTPSPPRRSSPGRGRSPRRgpspacsdssTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSE 560
Cdd:COG1196    564 EYLKAAKAGRATFLPLDKIRARAALAAAL----------ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  561 SERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQR 640
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834689  641 DRLEEEQEDAVQdgARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 704
Cdd:COG1196    714 EERLEEELEEEA--LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 794-1441 1.57e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.18  E-value: 1.57e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  794 RLEQEVARQGLEGSLRVAEQAQEvLEQQLPTLRHERS-----RLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAA 868
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKE-LKAELRELELALLvlrleELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  869 REKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGEL 948
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  949 AGLRQQIIAIQEK--ASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEE 1026
Cdd:TIGR02168  354 ESLEAELEELEAEleELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1027 LLARLEAEKEELSEEIATLqQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQK---------R 1097
Cdd:TIGR02168  434 ELKELQAELEELEEELEEL-QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkalL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1098 DAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQ--EVRRLQEQAQDLGKQRDSCL-------------REAEELRTQ 1162
Cdd:TIGR02168  513 KNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavVVENLNAAKKAIAFLKQNELgrvtflpldsikgTEIQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1163 LRLLEDARDGLRRELLEAQRKLR--------------ESQEGREVQRQEAGELR--------------RSLGEGAKEREA 1214
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvdDLDNALELAKKLRPGYRivtldgdlvrpggvITGGSAKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1215 LRRSNE--ELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKML 1292
Cdd:TIGR02168  673 LERRREieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1293 DSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEE 1372
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834689 1373 ARGTEKQqldhARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALR 1441
Cdd:TIGR02168  833 IAATERR----LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE 897
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1179-1859 2.43e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 2.43e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1179 EAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEeLRAAVKKAESERISLKLanEDKEQKLALLEEARTAVG 1258
Cdd:COG1196    176 EAERKLEATEENLERLEDILGELERQLEPLERQAEKAERYRE-LKEELKELEAELLLLKL--RELEAELEELEAELEELE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1259 KEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASL 1338
Cdd:COG1196    253 AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEEL 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1339 EVMRQELQVAQRKLQEQEGEFRTRERRL---LGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGL 1415
Cdd:COG1196    333 EELEEELEELEEELEEAEEELEEAEAELaeaEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1416 EAELARVEAQRRAAEAQLGGLRSALRRglglgrapspaprpvpgspARDAAaggsgdglsspsnlecspgsqppspgpat 1495
Cdd:COG1196    413 LERLERLEEELEELEEALAELEEEEEE-------------------EEEAL----------------------------- 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1496 spappdldpETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLS 1575
Cdd:COG1196    445 ---------EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1576 GVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKIskmkanetklegdkRRLKEVLDASESRTVKLE 1655
Cdd:COG1196    516 LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAI--------------EYLKAAKAGRATFLPLDK 581

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1656 LQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAgtlqLTVERLNGALAKVEESEGALRDKVRGLTEAL 1735
Cdd:COG1196    582 IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT----LVAARLEAALRRAVTLAGRLREVTLEGEGGS 657

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1736 AQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQL 1815
Cdd:COG1196    658 AGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 1622834689 1816 REVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEA 1859
Cdd:COG1196    738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781
PTZ00121 PTZ00121
MAEBL; Provisional
 840-1430 2.71e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 82.50  E-value: 2.71e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  840 SRQLSGREQELEQARRAAQRQMEALERAAREKEAlaKERAGLAVQLAAAERegrtlSEEATRLRLEKEALEGSLFEVQRQ 919
Cdd:PTZ00121  1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEA--KKKAEDARKAEEARK-----AEDARKAEEARKAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  920 LAqlEARREHLEAEGQALLLAKETltgelaglrQQIIAIQEKASLDKELMAQKLVQAER-EAQASLREQRAAHEED-LQR 997
Cdd:PTZ00121  1160 AE--DARKAEEARKAEDAKKAEAA---------RKAEEVRKAEELRKAEDARKAEAARKaEEERKAEEARKAEDAKkAEA 1228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  998 LQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEglLLAESEKQQALSLKESEKTALSEK 1077
Cdd:PTZ00121  1229 VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE--LKKAEEKKKADEAKKAEEKKKADE 1306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1078 LMGtrhslatiSLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVA---AHAQEVRRLQEQAQDLGKQRDSCLR 1154
Cdd:PTZ00121  1307 AKK--------KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAeaeAAADEAEAAEEKAEAAEKKKEEAKK 1378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1155 EAEELRTQLRLLEDArDGLRRELLEAQRKLRESQEgREVQRQEAGELRRSLGEGAKEREALRRSNEELRA--AVKKAESE 1232
Cdd:PTZ00121  1379 KADAAKKKAEEKKKA-DEAKKKAEEDKKKADELKK-AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEA 1456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1233 RISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL--AELQGRL 1310
Cdd:PTZ00121  1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkAEEAKKA 1536

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1311 ALGERAEKESRRETLGLRQRLLKGEaslevmrQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELK 1390
Cdd:PTZ00121  1537 DEAKKAEEKKKADELKKAEELKKAE-------EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1622834689 1391 LEATRAEAAEL-GLRLSAAEGRAQGLEAELARVEAQRRAAE 1430
Cdd:PTZ00121  1610 EEAKKAEEAKIkAEELKKAEEEKKKVEQLKKKEAEEKKKAE 1650
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1387-1975 4.11e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.52  E-value: 4.11e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1387 LELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRRglglgrapspaprpvpgspARDAA 1466
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEE-------------------LRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1467 AggsgdglsspsNLECSPGSQPPSPGPATSpappdlDPETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAER 1546
Cdd:COG1196    277 E-----------ELELELEEAQAEEYELLA------ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1547 DHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKM 1626
Cdd:COG1196    340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1627 KANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLT 1706
Cdd:COG1196    420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1707 VERLNGALAKVEES-----------EGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQ 1775
Cdd:COG1196    500 EADYEGFLEGVKAAlllaglrglagAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1776 ALSEARKQSSSLGEQVQTLRGeVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALA 1855
Cdd:COG1196    580 DKIRARAALAAALARGAIGAA-VDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1856 QLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLE 1935
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1622834689 1936 QSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEA 1975
Cdd:COG1196    739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1505-2004 7.20e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.75  E-value: 7.20e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1505 ETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQ 1584
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1585 EESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNS 1744
Cdd:COG1196    395 AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1745 TQDKNLHLQKALTACEHDRQVLQERLDAARQALSEAR--KQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQR 1822
Cdd:COG1196    475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKaaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1823 QEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAE 1902
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1903 KGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHRQ 1982
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500
                   ....*....|....*....|..
gi 1622834689 1983 RVRGLEEQVSTLKGQLQQELRR 2004
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREE 736
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1517-2007 8.60e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.37  E-value: 8.60e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1517 ELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEEsvrrsererr 1596
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA---------- 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1597 atldQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDRE 1676
Cdd:COG1196    296 ----ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1677 AQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKAL 1756
Cdd:COG1196    372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1757 TACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQkL 1836
Cdd:COG1196    452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL-I 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1837 QDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRT---LDKVEREKLRSHEDTVRLSAEKGRLDRTLTGA 1913
Cdd:COG1196    531 GVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpLDKIRARAALAAALARGAIGAAVDLVASDLRE 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1914 ELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHRQRVRGLEEQVST 1993
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690

                          490
                   ....*....|....
gi 1622834689 1994 LKGQLQQELRRSSA 2007
Cdd:COG1196    691 EELELEEALLAEEE 704
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 79-878 3.36e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.56  E-value: 3.36e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   79 LQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQtlrLESGELETQEprgLVRQSVELRRQLQEEQASYRRK 158
Cdd:TIGR02168  286 LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE---LESKLDELAE---ELAELEEKLEELKEELESLEAE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  159 LQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRlrntEHSQDLESALIRLEEEQQRSASLAQVNAM 238
Cdd:TIGR02168  360 LEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE----ARLERLEDRRERLQQEIEELLKKLEEAEL 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  239 LREQLDQAGLanQALSEDIRKVTSDWARSRKELEQREAAWRREEESFNAYFSNEHSRLLLLwrqvvgfrrlvsevkmfte 318
Cdd:TIGR02168  436 KELQAELEEL--EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL------------------- 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  319 RDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKAdlSAR 398
Cdd:TIGR02168  495 ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNE--LGR 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  399 VTELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRlqeqaaletedgeglqqTLRDLAQAVLSDSESGVQLSGSERTAD 478
Cdd:TIGR02168  573 VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLV-----------------KFDPKLRKALSYLLGGVLVVDDLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  479 ASDGSLRGLSGQRTPSpprrsspgrGRSPRRGPSPACSDSSTlalIHSALHKRQlQVQDMRGRYEASQDLLGTLRKQLSD 558
Cdd:TIGR02168  636 ELAKKLRPGYRIVTLD---------GDLVRPGGVITGGSAKT---NSSILERRR-EIEELEEKIEELEEKIAELEKALAE 702

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  559 SESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRR 638
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  639 QRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRV 718
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  719 ELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAAL-QGRQRQAEQEATVAREEQERLEELRLEQ 797
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELrRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  798 EVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLS----------RQLSGREQELEQARRAAQRQMEALERA 867
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGpvnlaaieeyEELKERYDFLTAQKEDLTEAKETLEEA 1022

                          810
                   ....*....|.
gi 1622834689  868 AREKEALAKER 878
Cdd:TIGR02168 1023 IEEIDREARER 1033
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
547-1027 6.25e-14

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 77.77  E-value: 6.25e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  547 DLLGTLRKQLSDSESERRALEEQ---LQRLRDKTDGAMQAQEDAQREVQRLRSANELLS-------REKSNLAHSLQVAQ 616
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQreqARETRDEADEVLEEHEERREELETLEAEIEDLRetiaeteREREELAEEVRDLR 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  617 QQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQR 696
Cdd:PRK02224   286 ERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  697 DMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQA 776
Cdd:PRK02224   366 AELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEA 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  777 EQeatvareeqerlEELRLEQEVARQGLEGSLRV-----AEQAQEVLEQQLPTLRHERSRLQ---EQLAQLSRQLSGREQ 848
Cdd:PRK02224   446 EA------------LLEAGKCPECGQPVEGSPHVetieeDRERVEELEAELEDLEEEVEEVEerlERAEDLVEAEDRIER 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  849 ELEQARRAAQRQMEALERAAREKEALAKERAglavQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 928
Cdd:PRK02224   514 LEERREDLEELIAERRETIEEKRERAEELRE----RAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  929 HLEAEgQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKlvqAEREAQASLREQRAAHEEDLQRLQREKEA---- 1004
Cdd:PRK02224   590 SLERI-RTLLAAIADAEDEIERLREKREALAELNDERRERLAEK---RERKRELEAEFDEARIEEAREDKERAEEYleqv 665

                          490       500
                   ....*....|....*....|....*
gi 1622834689 1005 --AWRELEAERAQLQSQLQREQEEL 1027
Cdd:PRK02224   666 eeKLDELREERDDLQAEIGAVENEL 690
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1112-1887 7.86e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.42  E-value: 7.86e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1112 ALTSELRDLRAQLEEA---VAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLR-LLEDARDGLRRELLEAQRKLRES 1187
Cdd:TIGR02169  227 ELLKEKEALERQKEAIerqLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKdLGEEEQLRVKEKIGELEAEIASL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1188 QEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTG 1267
Cdd:TIGR02169  307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1268 LQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQV 1347
Cdd:TIGR02169  387 LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1348 AQRKLQEQEGEFRTRERRLLGSLEEARGTEKQqldhARGLELKLEATRAEAAELGLRLSAaegrAQGLEAELARVEAQRR 1427
Cdd:TIGR02169  467 YEQELYDLKEEYDRVEKELSKLQRELAEAEAQ----ARASEERVRGGRAVEEVLKASIQG----VHGTVAQLGSVGERYA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1428 AAEAQLGGLRS---------------ALRRGLGLGRAP------SPAPRPVPGSPARDAAAGGSGDGLSSPSNLE----- 1481
Cdd:TIGR02169  539 TAIEVAAGNRLnnvvveddavakeaiELLKRRKAGRATflplnkMRDERRDLSILSEDGVIGFAVDLVEFDPKYEpafky 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1482 ----------CSPGSQPPSPGPATSPAPPDLDP--------ETVRGALQEFLQELRSAQRERDDLRtqtsALSHQLAEME 1543
Cdd:TIGR02169  619 vfgdtlvvedIEAARRLMGKYRMVTLEGELFEKsgamtggsRAPRGGILFSRSEPAELQRLRERLE----GLKRELSSLQ 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1544 AERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKI 1623
Cdd:TIGR02169  695 SELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDL 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1624 SKMKANETKLEGDKRRlkEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTL 1703
Cdd:TIGR02169  775 HKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSI 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1704 QLTVERLNGALAKVEESEGALRDKVRGLTEALAqssaslnstqdknlHLQKALTACEHDRQVLQERLDAARQALSEARKQ 1783
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESRLG--------------DLKKERDELEAQLRELERKIEELEAQIEKKRKR 918

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1784 SSSLGEQVQTLRGEVADLE---LQQVEAEGQLQQLREVLRQRQEGEAA--ALHMVQKLQ-DERRLLQERLGSLQRALAQL 1857
Cdd:TIGR02169  919 LSELKAKLEALEEELSEIEdpkGEDEEIPEEELSLEDVQAELQRVEEEirALEPVNMLAiQEYEEVLKRLDELKEKRAKL 998

                          810       820       830
                   ....*....|....*....|....*....|.
gi 1622834689 1858 EAEKREV-ERSALRLEKDRVALRRTLDKVER 1887
Cdd:TIGR02169  999 EEERKAIlERIEEYEKKKREVFMEAFEAINE 1029
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1262-1929 9.69e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 9.69e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1262 GELRTGLQEVERSRLEARReLQELRRQMKMLDSEntRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVM 1341
Cdd:COG1196    196 GELERQLEPLERQAEKAER-YRELKEELKELEAE--LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1342 RQELQVAQRKLQEQegefRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELAR 1421
Cdd:COG1196    273 RLELEELELELEEA----QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1422 VEAQRRAAEAQLgglrsalrrglglgrapspaprpvpgspardaaaggsgdglsspsnlecspgsqppspgpatspappd 1501
Cdd:COG1196    349 AEEELEEAEAEL-------------------------------------------------------------------- 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1502 ldpETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEM 1581
Cdd:COG1196    361 ---AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1582 ALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASE--SRTVKLELQRR 1659
Cdd:COG1196    438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgfLEGVKAALLLA 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1660 SLEGELQRSRLGLSDREAQAQALQDR--VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQ 1737
Cdd:COG1196    518 GLRGLAGAVAVLIGVEAAYEAALEAAlaAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAI 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1738 SSASLNSTQDknlhlQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLRE 1817
Cdd:COG1196    598 GAAVDLVASD-----LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLA 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1818 VLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLdkvEREKLRSHEDTV 1897
Cdd:COG1196    673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL---LEELLEEEELLE 749

                          650       660       670
                   ....*....|....*....|....*....|..
gi 1622834689 1898 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEA 1929
Cdd:COG1196    750 EEALEELPEPPDLEELERELERLEREIEALGP 781
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1068-1865 5.65e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.25  E-value: 5.65e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1068 ESEKTALSEKLMGTRHSLATISLeMERQKRDAQSRQEQDRSTvnalTSELRDLRAQLEEA-VAAHAQEVRRLQEQAQDLG 1146
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDL-IIDEKRQQLERLRREREK----AERYQALLKEKREYeGYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1147 KQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQrqeageLRRSLGEGAKEREALRRSNEELRAAV 1226
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLR------VKEKIGELEAEIASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1227 KKAESERISLKlanEDKEQKLALLEEARTAVGKEAGELRTGLQEVErsrlEARRELQELRRQMKMLDSENTRLGRELAEL 1306
Cdd:TIGR02169  318 EDAEERLAKLE---AEIDKLLAEIEELEREIEEERKRRDKLTEEYA----ELKEELEDLRAELEEVDKEFAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1307 QGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEqegeFRTRERRLLGSLEEARGTEKQQLDHARG 1386
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE----LEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1387 LELKLEATRAEAAELGLRLSAaegraqgLEAELARVEAQRRAAEAQLGGLRSA---LRRGLG-----LGRAPSPAPRPVP 1458
Cdd:TIGR02169  467 YEQELYDLKEEYDRVEKELSK-------LQRELAEAEAQARASEERVRGGRAVeevLKASIQgvhgtVAQLGSVGERYAT 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1459 gspARDAAAGGSGDGLSSPSNL---ECSPGSQPPSPGPAT-------SPAPPDLDPETVRGA------LQEFLQELRSAQ 1522
Cdd:TIGR02169  540 ---AIEVAAGNRLNNVVVEDDAvakEAIELLKRRKAGRATflplnkmRDERRDLSILSEDGVigfavdLVEFDPKYEPAF 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1523 RE--RDDLRTQtsalshqlaEMEAERDH------ATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESvrrsere 1594
Cdd:TIGR02169  617 KYvfGDTLVVE---------DIEAARRLmgkyrmVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLR------- 680

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1595 rratlDQIATLERSLQATESELR--------------ASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRS 1660
Cdd:TIGR02169  681 -----ERLEGLKRELSSLQSELRrienrldelsqelsDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN 755

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1661 LEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKagtlqltverlngalaKVEESEGALRDKVRGLTEALAQSSA 1740
Cdd:TIGR02169  756 VKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIP----------------EIQAELSKLEEEVSRIEARLREIEQ 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1741 SLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLR 1820
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR 899

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*
gi 1622834689 1821 QRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVE 1865
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 84-672 7.39e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 7.39e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   84 QLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQT-LRLESGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAY 162
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  163 QEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRNTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQ 242
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  243 LDQAGLANQALSEDIRKVTSDWARSRKELEQREAAWRREEESFNAYFSNEHSRLLLLwrqvvgfrrlvsevkmftERDLL 322
Cdd:COG1196    395 AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE------------------AELEE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  323 QLGGELARTSRAVQEAGLGLSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTEL 402
Cdd:COG1196    457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  403 GLAVE-----RLQKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTA 477
Cdd:COG1196    537 EAALEaalaaALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  478 DASDGSLrglsgqrtpspprrsspgrgrsprrgpspacSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLS 557
Cdd:COG1196    617 VLGDTLL-------------------------------GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  558 DSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELR 637
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE 745

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1622834689  638 RQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLE 672
Cdd:COG1196    746 ELLEEEALEELPEPPDLEELERELERLEREIEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 846-1431 7.42e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 71.33  E-value: 7.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  846 REQELEQARRAaqRQMEALERAAREKEALAKERAGLAVQLAAAER--EGRTLSEEATRLRLEKEALEGSLFEVQRqLAQL 923
Cdd:PTZ00121  1189 KAEELRKAEDA--RKAEAARKAEEERKAEEARKAEDAKKAEAVKKaeEAKKDAEEAKKAEEERNNEEIRKFEEAR-MAHF 1265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  924 EARREHLEAE----GQALLLAKETLTGELAGLRQQIIAIQE---KASLDK--ELMAQKLVQAEREAQASLREQRAAHEED 994
Cdd:PTZ00121  1266 ARRQAAIKAEearkADELKKAEEKKKADEAKKAEEKKKADEakkKAEEAKkaDEAKKKAEEAKKKADAAKKKAEEAKKAA 1345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  995 LQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESE--KT 1072
Cdd:PTZ00121  1346 EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADeaKK 1425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1073 ALSEKlmgTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSC 1152
Cdd:PTZ00121  1426 KAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1153 LREAEELRT--QLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQE----AGELRRS--LGEGAKEREALRRSNEELRA 1224
Cdd:PTZ00121  1503 KKAAEAKKKadEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADelkkAEELKKAeeKKKAEEAKKAEEDKNMALRK 1582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1225 A--VKKAESERIS--LKLANEDKEQKLALL---EEARTAVG--KEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSE 1295
Cdd:PTZ00121  1583 AeeAKKAEEARIEevMKLYEEEKKMKAEEAkkaEEAKIKAEelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1296 NTRLGRELAELQGRLALGERAEKESRRetlglrqrllKGEASLEVMRQELQVAQRKLQEQEgefrtrERRllgSLEEARG 1375
Cdd:PTZ00121  1663 AAEEAKKAEEDKKKAEEAKKAEEDEKK----------AAEALKKEAEEAKKAEELKKKEAE------EKK---KAEELKK 1723

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622834689 1376 TEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEA 1431
Cdd:PTZ00121  1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA 1779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1578-1994 1.02e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.35  E-value: 1.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1578 QAEMALQEESVRRSERERRATL--DQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLE 1655
Cdd:COG1196    208 QAEKAERYRELKEELKELEAELllLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1656 LQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEAL 1735
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1736 AQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQL 1815
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1816 REVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEA-EKREVERSALRLEKDRVALRRTLDKVEREKLRSHE 1894
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAArLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1895 DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLE 1974
Cdd:COG1196    528 VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                          410       420
                   ....*....|....*....|
gi 1622834689 1975 ARERAHRQRVRGLEEQVSTL 1994
Cdd:COG1196    608 LREADARYYVLGDTLLGRTL 627
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
680-1311 1.24e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 70.33  E-value: 1.24e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  680 KELVEVREALSRATLQRDMLQAEKaEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLsklsalnesLAQDKLDLNRLV 759
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEPIR-ELAERYAAARERLAELEYLRAALRLWFAQRRLEL---------LEAELEELRAEL 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  760 AQLEEEKAALQGRQRQAEQEATVAREeqerleelrleqevARQGLEGS-LRVAEQAQEVLEQQLPTLRHERSRLQEQLAQ 838
Cdd:COG4913    305 ARLEAELERLEARLDALREELDELEA--------------QIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  839 LSRQLSGREQELEQARRAAQrqmEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQR 918
Cdd:COG4913    371 LGLPLPASAEEFAALRAEAA---ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRD 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  919 QLAQ---------------LEARREHLEAE--------GQALLLA--------------KETLTGELAGLR-QQIIAIQE 960
Cdd:COG4913    448 ALAEalgldeaelpfvgelIEVRPEEERWRgaiervlgGFALTLLvppehyaaalrwvnRLHLRGRLVYERvRTGLPDPE 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  961 KASLDKELMAQKLVQAEREAQASLREQ--------RAAHEEDLQRLQR---------EKEAAWRELEAERAQLQSQLQRE 1023
Cdd:COG4913    528 RPRLDPDSLAGKLDFKPHPFRAWLEAElgrrfdyvCVDSPEELRRHPRaitragqvkGNGTRHEKDDRRRIRSRYVLGFD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1024 QEELLARLEAEKEELSEEIATLQQERDEglllaesekqqalslkesektalseklmgtrhsLATISLEMERQKRDAQSRQ 1103
Cdd:COG4913    608 NRAKLAALEAELAELEEELAEAEERLEA---------------------------------LEAELDALQERREALQRLA 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1104 EQDRSTVN--ALTSELRDLRAQLEEAVAAHAqEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQ 1181
Cdd:COG4913    655 EYSWDEIDvaSAEREIAELEAELERLDASSD-DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1182 RKLRE-SQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISL-KLANEDKEQKLALLEEARTAVGk 1259
Cdd:COG4913    734 DRLEAaEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELeRAMRAFNREWPAETADLDADLE- 812

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622834689 1260 EAGELRTGLQEVERSRLEARRElqelrrqmKMLDSENTRLGRELAELQGRLA 1311
Cdd:COG4913    813 SLPEYLALLDRLEEDGLPEYEE--------RFKELLNENSIEFVADLLSKLR 856
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
534-1027 1.36e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 70.33  E-value: 1.36e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  534 QVQDMRGRYEASQDLLGTLRKQLsdsESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQ 613
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQI---ELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  614 VAQQQAEELRQEREKLQAAQEELRRQR--------DRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEV 685
Cdd:COG4913    306 RLEAELERLEARLDALREELDELEAQIrgnggdrlEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  686 REALSRAtlqRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQ--------DSLSKLSALNESLAQDKLDLnR 757
Cdd:COG4913    386 RAEAAAL---LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLErrksnipaRLLALRDALAEALGLDEAEL-P 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  758 LVAQL----EEEKA-------ALQGRQR----QAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEqQL 822
Cdd:COG4913    462 FVGELievrPEEERwrgaierVLGGFALtllvPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAG-KL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  823 PTLRHE-RSRLQEQLAQL-SRQLSGREQELEQARRAAQRQ-MEALERAAREK--------------------EALAKERA 879
Cdd:COG4913    541 DFKPHPfRAWLEAELGRRfDYVCVDSPEELRRHPRAITRAgQVKGNGTRHEKddrrrirsryvlgfdnraklAALEAELA 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  880 GLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLF---------EVQRQLAQLEARREHLEAEGQALLLAKE-------- 942
Cdd:COG4913    621 ELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeidvaSAEREIAELEAELERLDASSDDLAALEEqleeleae 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  943 --TLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREK--EAAWRELEAERAQLQS 1018
Cdd:COG4913    701 leELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAveRELRENLEERIDALRA 780


                   ....*....
gi 1622834689 1019 QLQREQEEL 1027
Cdd:COG4913    781 RLNRAEEEL 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
530-1012 2.03e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 69.56  E-value: 2.03e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  530 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQ--------EDAQREVQRLRSANELL 601
Cdd:COG4913    278 RAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIrgnggdrlEQLEREIERLERELEER 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  602 SREKSNLAHSLQVAQQQ----AEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSV 677
Cdd:COG4913    358 ERRRARLEALLAALGLPlpasAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  678 LAKELVEVREALSRAtlqrdmLQAEKAE---VAEALTKAEAGR-----VELELSMTKLR--AEEASLQDSLS-------- 739
Cdd:COG4913    438 IPARLLALRDALAEA------LGLDEAElpfVGELIEVRPEEErwrgaIERVLGGFALTllVPPEHYAAALRwvnrlhlr 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  740 ------KLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGL--------E 805
Cdd:COG4913    512 grlvyeRVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRFDYVCVDSPEELRRHPRAITRAGQvkgngtrhE 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  806 GSLRVAEQAQEVL----EQQLPTLRHERSRLQEQLAQLSRQLSGREQELE--QARRAAQRQMEALERAAREKEALAKERA 879
Cdd:COG4913    592 KDDRRRIRSRYVLgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDalQERREALQRLAEYSWDEIDVASAEREIA 671

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  880 GLAVQLAAAER---EGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLtGELAGLRQQII 956
Cdd:COG4913    672 ELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA-EDLARLELRAL 750

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622834689  957 AIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAE 1012
Cdd:COG4913    751 LEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETAD 806
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 564-897 7.36e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.79  E-value: 7.36e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  564 RALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRL 643
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  644 EEEQEDAVQDGARVRRELERSHRQLEQLEgkrsvlakelvevreaLSRATLQRDMLQAEKAEVAEALTKAEAGRVELELS 723
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLE----------------EALNDLEARLSHSRIPEIQAELSKLEEEVSRIEAR 813

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  724 MTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQG 803
Cdd:TIGR02169  814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  804 LEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQE----------------LEQARRAAQRQMEALE-- 865
Cdd:TIGR02169  894 LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPkgedeeipeeelsledVQAELQRVEEEIRALEpv 973

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1622834689  866 --RAAREKEALAKERAGLAVQLAAAEREGRTLSE 897
Cdd:TIGR02169  974 nmLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
809-1367 1.29e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 66.86  E-value: 1.29e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  809 RVAEQAQEVLEQ--QLPTLRHERSRLQEQLAQLS--RQLSGREQELEQARRAAQRQMEALE--RAAREKEALAKERAGLA 882
Cdd:COG4913    222 DTFEAADALVEHfdDLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRlwFAQRRLELLEAELEELR 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  883 VQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQ-RQLAQLEARREHLEAEgqalllaKETLTGELAGLRQQIIAIQEK 961
Cdd:COG4913    302 AELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERE-------LEERERRRARLEALLAALGLP 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  962 ASLDKE------LMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQlQSQLQREQEELLARLEAEK 1035
Cdd:COG4913    375 LPASAEefaalrAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR-KSNIPARLLALRDALAEAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1036 EELSEE-------IATLQQERD-----EGLLlaeseKQQALSLKESEKT--ALSEKLMGTRHSLATISLEMERQKRDAQS 1101
Cdd:COG4913    454 GLDEAElpfvgelIEVRPEEERwrgaiERVL-----GGFALTLLVPPEHyaAALRWVNRLHLRGRLVYERVRTGLPDPER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1102 RQEQDRSTVNALTSELRDLRAQLEEAVAAHAQevRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELL--- 1178
Cdd:COG4913    529 PRLDPDSLAGKLDFKPHPFRAWLEAELGRRFD--YVCVDSPEELRRHPRAITRAGQVKGNGTRHEKDDRRRIRSRYVlgf 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1179 EAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANE--DKEQKLALLEEARTA 1256
Cdd:COG4913    607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREiaELEAELERLDASSDD 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1257 VGkeagELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEA 1336
Cdd:COG4913    687 LA----ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDA 762

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1622834689 1337 SLEVMRQELQVAQRKLQEQEGEFRTRERRLL 1367
Cdd:COG4913    763 VERELRENLEERIDALRARLNRAEEELERAM 793
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1602-1937 1.43e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.63  E-value: 1.43e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1602 IATLERSLQATESELRASQEKISKmkaNETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQA 1681
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIER---LDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1682 LQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKV--------EESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQ 1753
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkikdlgEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1754 KALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMV 1833
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1834 QKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGA 1913
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          330       340
                   ....*....|....*....|....
gi 1622834689 1914 ELELAEAQRQIQQLEAQVVVLEQS 1937
Cdd:TIGR02169  482 EKELSKLQRELAEAEAQARASEER 505
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 550-1374 3.52e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 65.38  E-value: 3.52e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  550 GTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQ-------VAQQQAEEL 622
Cdd:pfam02463  142 GKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQakkaleyYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  623 RQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAE 702
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  703 KAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATV 782
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  783 AREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQME 862
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  863 ALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKE 942
Cdd:pfam02463  462 KDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  943 TLTGELAGLRQQIIAIQEKASLDKE--------LMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERA 1014
Cdd:pfam02463  542 KVAISTAVIVEVSATADEVEERQKLvraltelpLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1015 QLQSQLQREQEELLARLEAEKEELSEEIATLQQERdeglLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER 1094
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEE----GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRR 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1095 QKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLR 1174
Cdd:pfam02463  698 QLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1175 RELLEAQRKLRESQEGREVQRQEagELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEAR 1254
Cdd:pfam02463  778 EEREKTEKLKVEEEKEEKLKAQE--EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1255 TAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETlgLRQRLLKG 1334
Cdd:pfam02463  856 LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE--EAEILLKY 933

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1622834689 1335 EASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEAR 1374
Cdd:pfam02463  934 EEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 984-1719 3.66e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.47  E-value: 3.66e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  984 LREQRAaHEEDLQRLQREKE--------AAWRELEAERAQLQSQLQREQEELlARLEAEKEELSEEIATLQQERDEglll 1055
Cdd:TIGR02169  203 LRRERE-KAERYQALLKEKReyegyellKEKEALERQKEAIERQLASLEEEL-EKLTEEISELEKRLEEIEQLLEE---- 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1056 aESEKQQALSLKES-EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEavaaHAQE 1134
Cdd:TIGR02169  277 -LNKKIKDLGEEEQlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEE----ERKR 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1135 VRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGE------G 1208
Cdd:TIGR02169  352 RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADlnaaiaG 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1209 AKER-EALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRR 1287
Cdd:TIGR02169  432 IEAKiNELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRA 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1288 QMKMLDSEN-------TRLGRELAELQGRL--ALGER------AEKESRRETLGLRQRLLKGEAS------LEVMRQELQ 1346
Cdd:TIGR02169  512 VEEVLKASIqgvhgtvAQLGSVGERYATAIevAAGNRlnnvvvEDDAVAKEAIELLKRRKAGRATflplnkMRDERRDLS 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1347 VAQRK--------LQEQEGEFRTRERRLLGS--LEEARGTEKQQLDHARGLELKLEATRAEAAELG--LRLSAAEGRAQG 1414
Cdd:TIGR02169  592 ILSEDgvigfavdLVEFDPKYEPAFKYVFGDtlVVEDIEAARRLMGKYRMVTLEGELFEKSGAMTGgsRAPRGGILFSRS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1415 LEAELARVEAQRRAAEAQLGGLRSALRRGLGLgrapspaprpvpgspaRDAAAGGSGDGLSSPSNLECSPGSQPPspgpa 1494
Cdd:TIGR02169  672 EPAELQRLRERLEGLKRELSSLQSELRRIENR----------------LDELSQELSDASRKIGEIEKEIEQLEQ----- 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1495 tspappdlDPETVRGALQEFLQELRSAQRER--------------DDLRTQTSALSHQLAEMEAERDHATLR-----ARQ 1555
Cdd:TIGR02169  731 --------EEEKLKERLEELEEDLSSLEQEIenvkselkeleariEELEEDLHKLEEALNDLEARLSHSRIPeiqaeLSK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1556 LQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEG 1635
Cdd:TIGR02169  803 LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1636 DKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVAD------SEVKAGTLQLTVER 1709
Cdd:TIGR02169  883 RLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeEELSLEDVQAELQR 962

                          810
                   ....*....|
gi 1622834689 1710 LNGALAKVEE 1719
Cdd:TIGR02169  963 VEEEIRALEP 972
mukB PRK04863
chromosome partition protein MukB;
523-1308 1.65e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 63.44  E-value: 1.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  523 LIHSALHKRQlQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLS 602
Cdd:PRK04863   284 HLEEALELRR-ELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  603 ReksnLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQE-------------DAVQDGARVRRELERSHRQLE 669
Cdd:PRK04863   363 R----LEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQaldvqqtraiqyqQAVQALERAKQLCGLPDLTAD 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  670 QLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQdsLSKLSALNESLA 749
Cdd:PRK04863   439 NAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRR--LREQRHLAEQLQ 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  750 QDKLDLNRLVAQLEEEKAAlQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHER 829
Cdd:PRK04863   517 QLRMRLSELEQRLRQQQRA-ERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARI 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  830 SRL----------QEQLAQLSRQlSGREQEleqarrAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLS--- 896
Cdd:PRK04863   596 QRLaarapawlaaQDALARLREQ-SGEEFE------DSQDVTEYMQQLLERERELTVERDELAARKQALDEEIERLSqpg 668

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  897 -EEATRLRLEKEALEGSL---------------FE-----------------VQRQLAQLEARREHL------------- 930
Cdd:PRK04863   669 gSEDPRLNALAERFGGVLlseiyddvsledapyFSalygparhaivvpdlsdAAEQLAGLEDCPEDLyliegdpdsfdds 748

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  931 --EAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELmaqKLVQAEREAQASLREQRAAHEEDLQRL---------- 998
Cdd:PRK04863   749 vfSVEELEKAVVVKIADRQWRYSRFPEVPLFGRAAREKRI---EQLRAEREELAERYATLSFDVQKLQRLhqafsrfigs 825

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  999 ------QREKEAAWRELEAERAQLQSQLQREQEELLaRLEAEKEELSEEIATLQQERDE-GLLLAESEKQQALSLKESEK 1071
Cdd:PRK04863   826 hlavafEADPEAELRQLNRRRVELERALADHESQEQ-QQRSQLEQAKEGLSALNRLLPRlNLLADETLADRVEEIREQLD 904

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1072 TALSEKLMGTRHSLATISLE---------------MERQKRDAQSRQEQDRSTVNALTsELRDLRAQLeeavaAHAQEVR 1136
Cdd:PRK04863   905 EAEEAKRFVQQHGNALAQLEpivsvlqsdpeqfeqLKQDYQQAQQTQRDAKQQAFALT-EVVQRRAHF-----SYEDAAE 978

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1137 RLQEQAQdlgkqrdsclrEAEELRTQLRLLEDARDGLRRELLEAQRKLRES-------QEGREVQRQEAGELRRSLG--- 1206
Cdd:PRK04863   979 MLAKNSD-----------LNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYnqvlaslKSSYDAKRQMLQELKQELQdlg 1047

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1207 ----EGAKEREALRRsnEELRAAVKKAESERISLklanedkEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARREL 1282
Cdd:PRK04863  1048 vpadSGAEERARARR--DELHARLSANRSRRNQL-------EKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAGW 1118

                          890       900
                   ....*....|....*....|....*.
gi 1622834689 1283 QELRRQMKMLDSENTRLGRELAELQG 1308
Cdd:PRK04863  1119 CAVLRLVKDNGVERRLHRRELAYLSA 1144
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1241-1858 1.85e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.01  E-value: 1.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1241 EDKEQKLALLEEARTAvGKEAGELRTGLQEVERsrLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKES 1320
Cdd:COG4913    245 EDAREQIELLEPIREL-AERYAAARERLAELEY--LRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDAL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1321 RRETLGLRQRLLK-GEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLGSLEEARGTEKQQL--------DHARGLELKL 1391
Cdd:COG4913    322 REELDELEAQIRGnGGDRLEQLEREIERLERELEERERR-RARLEALLAALGLPLPASAEEFaalraeaaALLEALEEEL 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1392 EATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRRGLGLGRAPSP--------APRPVPGSPAR 1463
Cdd:COG4913    401 EALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELPfvgelievRPEEERWRGAI 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1464 DAAAGGSGDGLSSPSNLECSPGSQppspgpatspappdLDPETVRGALQefLQELRSAQRERDDLRTQTSALSHQL---- 1539
Cdd:COG4913    481 ERVLGGFALTLLVPPEHYAAALRW--------------VNRLHLRGRLV--YERVRTGLPDPERPRLDPDSLAGKLdfkp 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1540 --------AEMEAERDHATLRarqlqkAVAESEEARRSV--DG--RLSGVQAEMALQEESVRRSERERRATlDQIATLER 1607
Cdd:COG4913    545 hpfrawleAELGRRFDYVCVD------SPEELRRHPRAItrAGqvKGNGTRHEKDDRRRIRSRYVLGFDNR-AKLAALEA 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1608 SLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDR-----EAQAQAL 1682
Cdd:COG4913    618 ELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDdlaalEEQLEEL 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1683 QDRVDSLQRQVADSEVKAGTLQltvERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHD 1762
Cdd:COG4913    698 EAELEELEEELDELKGEIGRLE---KELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEER 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1763 RQVLQERLDAARQALSEARKQ-SSSLGEQVQTLRGEVADLE-----LQQVEAEG---QLQQLREVLRQRQEGEAAALHmv 1833
Cdd:COG4913    775 IDALRARLNRAEEELERAMRAfNREWPAETADLDADLESLPeylalLDRLEEDGlpeYEERFKELLNENSIEFVADLL-- 852

                          650       660
                   ....*....|....*....|....*
gi 1622834689 1834 QKLQDERRLLQERLGSLQRALAQLE 1858
Cdd:COG4913    853 SKLRRAIREIKERIDPLNDSLKRIP 877
PTZ00121 PTZ00121
MAEBL; Provisional
 552-1109 1.93e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.24  E-value: 1.93e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  552 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQA 631
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKK 1399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  632 AQEELRRQRDRLEEEQEDAVQDGARVRRElerSHRQLEQLEGKrsvlAKELVEVREALSRATlqrdmlQAEKAEvaEALT 711
Cdd:PTZ00121  1400 AEEDKKKADELKKAAAAKKKADEAKKKAE---EKKKADEAKKK----AEEAKKADEAKKKAE------EAKKAE--EAKK 1464

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  712 KAEAGRVELELsmtKLRAEEASLQDSLSKLSalneslAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATvareeqerle 791
Cdd:PTZ00121  1465 KAEEAKKADEA---KKKAEEAKKADEAKKKA------EEAKKKADEAKKAAEAKKKADEAKKAEEAKKAD---------- 1525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  792 elrleqevarqglegSLRVAEQAQEVLEQQlptlRHERSRLQEQLAQLSRQLSGRE-QELEQARRAAQRQMEALERAARE 870
Cdd:PTZ00121  1526 ---------------EAKKAEEAKKADEAK----KAEEKKKADELKKAEELKKAEEkKKAEEAKKAEEDKNMALRKAEEA 1586

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  871 KEAlakERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEgslfevqrqlaqlEARREHLEAEGQALLLAKETLTGELAg 950
Cdd:PTZ00121  1587 KKA---EEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE-------------ELKKAEEEKKKVEQLKKKEAEEKKKA- 1649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  951 lrQQIIAIQEKASLDKELMAQKLVQAEREAQASLR--EQRAAHEEDLQRLQREKEAA--WRELEAERAQLQSQLQREQEE 1026
Cdd:PTZ00121  1650 --EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKaeEDEKKAAEALKKEAEEAKKAeeLKKKEAEEKKKAEELKKAEEE 1727

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1027 LLARLEAEKEELSEeiatlQQERDEGLLLAESEKQQALSLKESEktalsEKLMGTRHSLATISLEMERQKRDAQSRQEQD 1106
Cdd:PTZ00121  1728 NKIKAEEAKKEAEE-----DKKKAEEAKKDEEEKKKIAHLKKEE-----EKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797


                   ...
gi 1622834689 1107 RST 1109
Cdd:PTZ00121  1798 KKI 1800
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
979-1431 2.11e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 62.75  E-value: 2.11e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  979 EAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEelLARLEAEKEELSEEIATLQQERDEgLLLAES 1058
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE--LETLEAEIEDLRETIAETEREREE-LAEEVR 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1059 EKQQALSLKESEKTALSEKLMGTRHSLATISL---EMERQKRDAQSRQEQDRSTVNALTSELRDLRaqleEAVAAHAQEV 1135
Cdd:PRK02224   283 DLRERLEELEEERDDLLAEAGLDDADAEAVEArreELEDRDEELRDRLEECRVAAQAHNEEAESLR----EDADDLEERA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1136 RRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREAL 1215
Cdd:PRK02224   359 EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1216 R---RSNEELRAA-------------------------VKKAESERISLKLANEDKEQKLALLEEARTAvGKEAGELRTG 1267
Cdd:PRK02224   439 RervEEAEALLEAgkcpecgqpvegsphvetieedrerVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEER 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1268 LQEVE------RSRLEARRE-LQELRRQMKMLDSEN-------TRLGRELAELQGRLAL--GERAEKESRRETLGLRQRL 1331
Cdd:PRK02224   518 REDLEeliaerRETIEEKRErAEELRERAAELEAEAeekreaaAEAEEEAEEAREEVAElnSKLAELKERIESLERIRTL 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1332 LKGEASLEVMRQELQVAQRKLQEQE-------GEFRTRERRLLGSLEEARGTEKQQlDHARG------LELKLEATRAEA 1398
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNderrerlAEKRERKRELEAEFDEARIEEARE-DKERAeeyleqVEEKLDELREER 676

                          490       500       510
                   ....*....|....*....|....*....|....*.
gi 1622834689 1399 AELGLRLSAAEGRAQGLEA---ELARVEAQRRAAEA 1431
Cdd:PRK02224   677 DDLQAEIGAVENELEELEElreRREALENRVEALEA 712
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
534-1031 3.31e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 62.36  E-value: 3.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  534 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQ 613
Cdd:PRK02224   238 EADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARRE 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  614 VAQQQAEELRQEREKLQAAQEELRRQRDRLEE-------EQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 686
Cdd:PRK02224   318 ELEDRDEELRDRLEECRVAAQAHNEEAESLREdaddleeRAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELR 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  687 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELElsmTKLRAEEASLQDSLSKLSA---------LNESLAQDKLDLNR 757
Cdd:PRK02224   398 ERFGDAPVDLGNAEDFLEELREERDELREREAELE---ATLRTARERVEEAEALLEAgkcpecgqpVEGSPHVETIEEDR 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  758 -LVAQLEEEKAALQGRQRQAEQEATVAREEQErleelrleqevARQGLEGSLRVAEQAQEVLEQQLPTLRHERsrlqEQL 836
Cdd:PRK02224   475 eRVEELEAELEDLEEEVEEVEERLERAEDLVE-----------AEDRIERLEERREDLEELIAERRETIEEKR----ERA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  837 AQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLS------EEATRLRLEKEALE 910
Cdd:PRK02224   540 EELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAaiadaeDEIERLREKREALA 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  911 GSLFEVQRQLAQLEARREHLEAE--GQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQ-KLVQAEREAQASLREQ 987
Cdd:PRK02224   620 ELNDERRERLAEKRERKRELEAEfdEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEiGAVENELEELEELRER 699

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1622834689  988 RAAHEEDLQRLQREKEAAwRELEAERAQLQSQLQREQEELLARL 1031
Cdd:PRK02224   700 REALENRVEALEALYDEA-EELESMYGDLRAELRQRNVETLERM 742
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1521-1987 3.93e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.24  E-value: 3.93e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1521 AQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDG-RLSGVQAEMALQEESVRRSERERRATL 1599
Cdd:COG4913    286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGdRLEQLEREIERLERELEERERRRARLE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1600 DQIATLERSLQATESELRASQEKIskmKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSD----- 1674
Cdd:COG4913    366 ALLAALGLPLPASAEEFAALRAEA---AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNiparl 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1675 ---REAQAQALQDRVDSLQ-----RQVADSEVK------------AGTLQLTVERLNGALAKVEESEGALR---DKVRGL 1731
Cdd:COG4913    443 lalRDALAEALGLDEAELPfvgelIEVRPEEERwrgaiervlggfALTLLVPPEHYAAALRWVNRLHLRGRlvyERVRTG 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1732 TEALAQSSASLNSTQDKnlhlqkaLTACEHD-----RQVLQERLDAA-----------RQALSEA--RKQSSSLGE---- 1789
Cdd:COG4913    523 LPDPERPRLDPDSLAGK-------LDFKPHPfrawlEAELGRRFDYVcvdspeelrrhPRAITRAgqVKGNGTRHEkddr 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1790 ---------------QVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEgEAAALHMVQKLQDErrllQERLGSLQRAL 1854
Cdd:COG4913    596 rrirsryvlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQE-RREALQRLAEYSWD----EIDVASAEREI 670

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1855 AQLEAEKREVERSALRLEkdrvALRRTLDKVEREKlrshedtVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVL 1934
Cdd:COG4913    671 AELEAELERLDASSDDLA----ALEEQLEELEAEL-------EELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622834689 1935 EQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHRQRVRGL 1987
Cdd:COG4913    740 EDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
810-1332 1.63e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.63e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  810 VAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQlsgREQElEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAE 889
Cdd:PRK02224   196 IEEKEEKDLHERLNGLESELAELDEEIERYEEQ---REQA-RETRDEADEVLEEHEERREELETLEAEIEDLRETIAETE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  890 REGRTLSEEATRLRLEKEALEgslfevqRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASldkelM 969
Cdd:PRK02224   272 REREELAEEVRDLRERLEELE-------EERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQ-----A 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  970 AQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLqSQLQREQEELLARLEAEKEELSEEIATLQQER 1049
Cdd:PRK02224   340 HNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEI-EELEEEIEELRERFGDAPVDLGNAEDFLEELR 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1050 DEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRdaQSRQEQDRSTVNALTSELRDLRAQLE---- 1125
Cdd:PRK02224   419 EERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPH--VETIEEDRERVEELEAELEDLEEEVEevee 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1126 -----EAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGE 1200
Cdd:PRK02224   497 rleraEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAE 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1201 LRRSLGEGAKEREALRRSnEELRAAVKKAESERISLklaNEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLE-AR 1279
Cdd:PRK02224   577 LNSKLAELKERIESLERI-RTLLAAIADAEDEIERL---REKREALAELNDERRERLAEKRERKRELEAEFDEARIEeAR 652

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834689 1280 RELQELRRQMKMLDSENTRLGRELAELQGRL-----ALGERAEKESRRETLGLRQRLL 1332
Cdd:PRK02224   653 EDKERAEEYLEQVEEKLDELREERDDLQAEIgavenELEELEELRERREALENRVEAL 710
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1505-2000 2.18e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 2.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1505 ETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAE----RDHATLRARQLQKAVAESEEARRS--------VDG 1572
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEierlEARLERLEDRRERLQQEIEELLKKleeaelkeLQA 440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1573 RLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDA------ 1646
Cdd:TIGR02168  441 ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNqsglsg 520

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1647 -----SESRTVKLELQR---RSLEGELQ-----RSRLGLSDREAQAQALQDRVDSL---QRQVADSEVKAGTLQLTVERL 1710
Cdd:TIGR02168  521 ilgvlSELISVDEGYEAaieAALGGRLQavvveNLNAAKKAIAFLKQNELGRVTFLpldSIKGTEIQGNDREILKNIEGF 600

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1711 NGALAKVEESEGALRDKVRG----------LTEALAQSSASL-----------------------NSTQDKNLHLQKALT 1757
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYllggvlvvddLDNALELAKKLRpgyrivtldgdlvrpggvitggsAKTNSSILERRREIE 680

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1758 ACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQKLQ 1837
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1838 DERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELEL 1917
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1918 AEAQRQIQQLEAQVVVLEQSHSPAQLEVDAqqqqHLELQQEVERLRSAQVQTERTLEARERAHRQRVRGLEEQVSTLKGQ 1997
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEE----LESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRE 916


                   ...
gi 1622834689 1998 LQQ 2000
Cdd:TIGR02168  917 LEE 919
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 566-1230 2.27e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 59.75  E-value: 2.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  566 LEEQLQRLRDKTDGAMQAQ-EDAQREVQRLRSANELlsrEKSNLAHSLQVAQQQAEELRQErekLQAAQEELRRQRDRLE 644
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLlQQHQDRIEQLISEHEV---EITGLTEKASSARSQANSIQSQ---LEIIQEQARNQNSMYM 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  645 EEQEDAVQDGARVRRELERSHRQLEQlegKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTK--AEAGRVELEL 722
Cdd:pfam15921  317 RQLSDLESTVSQLRSELREAKRMYED---KIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKllADLHKREKEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  723 SMTKLRAEEASLQDSLSKLSA--LNESLAQDKLDLNRLVAQLEEEKAALQGRQRQaeqeatvareeqerleelrleQEVA 800
Cdd:pfam15921  394 SLEKEQNKRLWDRDTGNSITIdhLRRELDDRNMEVQRLEALLKAMKSECQGQMER---------------------QMAA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  801 RQGLEGSLrvaeqaqevleQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAG 880
Cdd:pfam15921  453 IQGKNESL-----------EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITK 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  881 LAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQalLLAKEtltGELAGLRQQiiaiqE 960
Cdd:pfam15921  522 LRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQ--LVGQH---GRTAGAMQV-----E 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  961 KASLDKELMAQKLvqaereaqaslreqraaHEEDLQRLQREKEAAWRELEAERAQLQSQLQReqeellarleaekeelse 1040
Cdd:pfam15921  592 KAQLEKEINDRRL-----------------ELQEFKILKDKKDAKIRELEARVSDLELEKVK------------------ 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1041 eiatlqqerdegLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDL 1120
Cdd:pfam15921  637 ------------LVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSA 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1121 RAQLE---------EAVAAHAQEVrrlqeqAQDLGKQRDSCLREAEELRTQLRLLEDArdglrreLLEAQRKLRESQEGR 1191
Cdd:pfam15921  705 QSELEqtrntlksmEGSDGHAMKV------AMGMQKQITAKRGQIDALQSKIQFLEEA-------MTNANKEKHFLKEEK 771

                          650       660       670
                   ....*....|....*....|....*....|....*....
gi 1622834689 1192 EVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAE 1230
Cdd:pfam15921  772 NKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
PTZ00121 PTZ00121
MAEBL; Provisional
 960-1709 3.28e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.38  E-value: 3.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  960 EKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLqrekEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELS 1039
Cdd:PTZ00121  1104 KKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKA----EEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1040 EEIATLQQERDEGLLLAESEK--QQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSEL 1117
Cdd:PTZ00121  1180 AARKAEEVRKAEELRKAEDARkaEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1118 RDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRREllEAQRKLRESQEGREVQRQE 1197
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD--EAKKKAEEAKKKADAAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1198 AGELRRSlGEGAKEREalRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTA--VGKEAGELRTGLQEVERSR 1275
Cdd:PTZ00121  1338 AEEAKKA-AEAAKAEA--EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdeAKKKAEEDKKKADELKKAA 1414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1276 LEARR--ELQELRRQMKMLDSENTRL--GRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRK 1351
Cdd:PTZ00121  1415 AAKKKadEAKKKAEEKKKADEAKKKAeeAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEE 1494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1352 LQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELglRLSAAEGRAQgleAELARVEAQRRAAEA 1431
Cdd:PTZ00121  1495 AKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE--KKKADELKKA---EELKKAEEKKKAEEA 1569

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1432 QlgglRSALRRGLGLGRApspaprpvpgspardaaaggsgdglsspsnlecspGSQPPSPGPATSPAPPDLDPETVRGAl 1511
Cdd:PTZ00121  1570 K----KAEEDKNMALRKA-----------------------------------EEAKKAEEARIEEVMKLYEEEKKMKA- 1609

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1512 qeflQELRSAQRERDDlrtqtsalSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRS 1591
Cdd:PTZ00121  1610 ----EEAKKAEEAKIK--------AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA 1677

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1592 ERERRATLDQiatlerslQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLG 1671
Cdd:PTZ00121  1678 EEAKKAEEDE--------KKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEA 1749

                          730       740       750
                   ....*....|....*....|....*....|....*...
gi 1622834689 1672 LSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVER 1709
Cdd:PTZ00121  1750 KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDE 1787
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 528-1377 3.48e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 58.90  E-value: 3.48e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  528 LHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQE---------------DAQREVQ 592
Cdd:TIGR00606  250 LKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYhnhqrtvrekerelvDCQRELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  593 RLRSANELLSREKSNLahslqVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQeDAVQDGARVRRELERSHR-QLEQL 671
Cdd:TIGR00606  330 KLNKERRLLNQEKTEL-----LVEQGRLQLQADRHQEHIRARDSLIQSLATRLEL-DGFERGPFSERQIKNFHTlVIERQ 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  672 EGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEAL----TKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNES 747
Cdd:TIGR00606  404 EDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIelkkEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKA 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  748 LAQ-DKLDLNRLVAQLEEEKAALQGRQ----RQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQA-------- 814
Cdd:TIGR00606  484 ERElSKAEKNSLTETLKKEVKSLQNEKadldRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKsrhsdelt 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  815 --------QEVLEQQLPTLRHERSRLQEQLAQLSRQLsgreQELEQARRAAQRQMEALEraarEKEALAKERAGLAVQLA 886
Cdd:TIGR00606  564 sllgyfpnKKQLEDWLHSKSKEINQTRDRLAKLNKEL----ASLEQNKNHINNELESKE----EQLSSYEDKLFDVCGSQ 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  887 AAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQI-IAIQEKASLD 965
Cdd:TIGR00606  636 DEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLrLAPDKLKSTE 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  966 KELmaqKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQrEQEELLARLEAEKEELSEEIATL 1045
Cdd:TIGR00606  716 SEL---KKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIE-EQETLLGTIMPEEESAKVCLTDV 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1046 QQERDEGLLLAESEKQQALSLKESEK-------TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRStVNALTSELR 1118
Cdd:TIGR00606  792 TIMERFQMELKDVERKIAQQAAKLQGsdldrtvQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQH-LKSKTNELK 870

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1119 DLRAQLEEAvaahAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEA 1198
Cdd:TIGR00606  871 SEKLQIGTN----LQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDI 946

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1199 GELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKlalleeartavgKEAGELRTGLQEVERSRLEA 1278
Cdd:TIGR00606  947 KEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQE------------KINEDMRLMRQDIDTQKIQE 1014

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1279 RRELQELRRQMKmlDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQ---ELQVAQRKLQEQ 1355
Cdd:TIGR00606 1015 RWLQDNLTLRKR--ENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQkgyEKEIKHFKKELR 1092

                          890       900
                   ....*....|....*....|..
gi 1622834689 1356 EGEFRTRERRLLGSLEEARGTE 1377
Cdd:TIGR00606 1093 EPQFRDAEEKYREMMIVMRTTE 1114
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
812-1364 3.93e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.54  E-value: 3.93e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  812 EQAQEVLEQQLPTLRHERSRLQEQLA---QLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERaglavqlaaa 888
Cdd:PRK03918   161 ENAYKNLGEVIKEIKRRIERLEKFIKrteNIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV---------- 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  889 eREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQalllaketltgELAGLRQQIIAIQEKASLDKEL 968
Cdd:PRK03918   231 -KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE-----------ELEEKVKELKELKEKAEEYIKL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  969 MA--QKLVQAEREAQ---ASLREQRAAHEEDLQRLQrEKEAAWRELEAERAQLQSQLQREQE-----ELLARLEAEKEEL 1038
Cdd:PRK03918   299 SEfyEEYLDELREIEkrlSRLEEEINGIEERIKELE-EKEERLEELKKKLKELEKRLEELEErhelyEEAKAKKEELERL 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1039 SEEIATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRD-----AQSRQEQDRSTVNAL 1113
Cdd:PRK03918   378 KKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgRELTEEHRKELLEEY 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1114 TSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDscLREAEELRTQLRLLEDARDGLRRELLEaqRKLRESQEGREV 1193
Cdd:PRK03918   458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE--LIKLKELAEQLKELEEKLKKYNLEELE--KKAEEYEKLKEK 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1194 QRQEAGELrRSLGEGAKEREALRRSNEELRAAVKKAESERISLK--------LANEDKEQKLALLEEARtavgKEAGELR 1265
Cdd:PRK03918   534 LIKLKGEI-KSLKKELEKLEELKKKLAELEKKLDELEEELAELLkeleelgfESVEELEERLKELEPFY----NEYLELK 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1266 TGLQEVERSRLEARRELQELRRQMKMLDSENTRLGR---ELAELQGRLAlgERAEKESRRETLGLRQRLLKGEASLEVMR 1342
Cdd:PRK03918   609 DAEKELEREEKELKKLEEELDKAFEELAETEKRLEElrkELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEELE 686

                          570       580
                   ....*....|....*....|..
gi 1622834689 1343 QELQVAQRKLQEQEGEFRTRER 1364
Cdd:PRK03918   687 KRREEIKKTLEKLKEELEEREK 708
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 608-859 4.08e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.85  E-value: 4.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  608 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVRE 687
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  688 ALSRATLQRDMLQAEKAEVAEALTKAEagrvelELSMTKLRAEEASLQDSLSKLSALNESLAQDKldlnRLVAQLEEEKA 767
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLG------RQPPLALLLSPEDFLDAVRRLQYLKYLAPARR----EQAEELRADLA 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  768 ALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGRE 847
Cdd:COG4942    161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240

                          250
                   ....*....|..
gi 1622834689  848 QELEQARRAAQR 859
Cdd:COG4942    241 ERTPAAGFAALK 252
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1068-1430 4.17e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.51  E-value: 4.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1068 ESEKTALSEKLMGTRHSLATISLEMER---QKRDAQ----------SRQEQDRSTVNALTSELRDLRAQLEEAV---AAH 1131
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERyeeQREQARetrdeadevlEEHEERREELETLEAEIEDLRETIAETErerEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1132 AQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLREsqegrevQRQEAGELRRSLGEGAKE 1211
Cdd:PRK02224   278 AEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEE-------CRVAAQAHNEEAESLRED 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1212 REALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKM 1291
Cdd:PRK02224   351 ADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAE 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1292 LDSENTRLGRELAELQGRLA------LGERAEKESRRETLG-LRQRLLKGEASLEVMRQELQVAQRKLQEQEgEFRTRER 1364
Cdd:PRK02224   431 LEATLRTARERVEEAEALLEagkcpeCGQPVEGSPHVETIEeDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAED 509

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834689 1365 RLLGSLEEARGTEKQQLDHARGLE---LKLEATRAEAAElgLRLSAAEGRAQGLEAELARVEAQRRAAE 1430
Cdd:PRK02224   510 RIERLEERREDLEELIAERRETIEekrERAEELRERAAE--LEAEAEEKREAAAEAEEEAEEAREEVAE 576
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 559-772 5.31e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.47  E-value: 5.31e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  559 SESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRR 638
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  639 QRDRLEEEQEDAVQDGARVRR-----------ELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVA 707
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRqpplalllspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622834689  708 EALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGR 772
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
904-1442 7.13e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.00  E-value: 7.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  904 LEKEALEGSLFEVQRQLAQL-EARREHLEAEGQALLLAketltgELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQA 982
Cdd:COG4913    218 LEEPDTFEAADALVEHFDDLeRAHEALEDAREQIELLE------PIRELAERYAAARERLAELEYLRAALRLWFAQRRLE 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  983 SLREQRAAHEEDLQRLQREK---EAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEgllLAESE 1059
Cdd:COG4913    292 LLEAELEELRAELARLEAELerlEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRAR---LEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1060 KQQALSLKESEK--TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQlEEAVAAHAQEVRR 1137
Cdd:COG4913    369 AALGLPLPASAEefAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR-KSNIPARLLALRD 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1138 lqEQAQDLGKQRDSC--------LREAEE---------LRTQ-LRLLEDARDglRRELLEA--QRKLRESQEGREVQRQE 1197
Cdd:COG4913    448 --ALAEALGLDEAELpfvgelieVRPEEErwrgaiervLGGFaLTLLVPPEH--YAAALRWvnRLHLRGRLVYERVRTGL 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1198 AGELRRSLGEGA-------KEREALRRSNEEL--RAAVKKAESERislKLANEDKeqklALLEEARTAVGKEAGELRTGL 1268
Cdd:COG4913    524 PDPERPRLDPDSlagkldfKPHPFRAWLEAELgrRFDYVCVDSPE---ELRRHPR----AITRAGQVKGNGTRHEKDDRR 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1269 QEVE--------RSRLEA-RRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEK------------ESRRETLGL 1327
Cdd:COG4913    597 RIRSryvlgfdnRAKLAAlEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeidvasaeREIAELEAE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1328 RQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRlLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSA 1407
Cdd:COG4913    677 LERLDASSDDLAALEEQLEELEAELEELEEELDELKGE-IGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERF 755

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1622834689 1408 AEGRAQGLEAELAR-VEAQRRAAEAQLGGLRSALRR 1442
Cdd:COG4913    756 AAALGDAVERELREnLEERIDALRARLNRAEEELER 791
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 559-1031 7.16e-08

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 57.89  E-value: 7.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  559 SESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANElLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQ--EEL 636
Cdd:PRK10246   214 TPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDE-LQQEASRRQQALQQALAAEEKAQPQLAALSLAQpaRQL 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  637 RRQRDRLeEEQEDAVqdgARVRRELERSHRQLEQLEGKRSvlakelvEVREALSRatlQRDMLQAEKAEVAEALTKAEAG 716
Cdd:PRK10246   293 RPHWERI-QEQSAAL---AHTRQQIEEVNTRLQSTMALRA-------RIRHHAAK---QSAELQAQQQSLNTWLAEHDRF 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  717 RVeLELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN-------RLVAQLEEEKAALQGRQRQAEQEATVAREEQER 789
Cdd:PRK10246   359 RQ-WNNELAGWRAQFSQQTSDREQLRQWQQQLTHAEQKLNalpaitlTLTADEVAAALAQHAEQRPLRQRLVALHGQIVP 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  790 LEELRLEQEVARQGlegslrvAEQAQEVLEQQLPTLRHERSRLQEQLAQLSR--QLSGREQELEQARRAAQRQMEALERA 867
Cdd:PRK10246   438 QQKRLAQLQVAIQN-------VTQEQTQRNAALNEMRQRYKEKTQQLADVKTicEQEARIKDLEAQRAQLQAGQPCPLCG 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  868 AREKEALAkerAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGE 947
Cdd:PRK10246   511 STSHPAVE---AYQALEPGVNQSRLDALEKEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVCAS 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  948 LAGLR-----------------QQIIAIQEKASLDKELMAQKlvQAEREAQASLREQRAAHEEDLQRL-----QREKEAA 1005
Cdd:PRK10246   588 LNITLqpqddiqpwldaqeeheRQLRLLSQRHELQGQIAAHN--QQIIQYQQQIEQRQQQLLTALAGYaltlpQEDEEAS 665

                          490       500
                   ....*....|....*....|....*.
gi 1622834689 1006 WRELEAERAQLQSQLQREQEELLARL 1031
Cdd:PRK10246   666 WLATRQQEAQSWQQRQNELTALQNRI 691
PTZ00121 PTZ00121
MAEBL; Provisional
 1207-1995 7.28e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.23  E-value: 7.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1207 EGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARtavgkeagELRTGLQEVERSRLEARRELQELR 1286
Cdd:PTZ00121  1057 EGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAK--------KTETGKAEEARKAEEAKKKAEDAR 1128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1287 RQMKMLDSENTRLGREL--AELQGRLALGERAEKESRRETLGLRQRLLKGEAS---LEVMR-QELQVAQRKLQEQEGEFR 1360
Cdd:PTZ00121  1129 KAEEARKAEDARKAEEArkAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAArkaEEVRKaEELRKAEDARKAEAARKA 1208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1361 TRERRLlgslEEARGTEKQQLDHA--RGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGglrS 1438
Cdd:PTZ00121  1209 EEERKA----EEARKAEDAKKAEAvkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA---D 1281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1439 ALRRGLGLGRAPspaprpvpgspardaaaggsgdglsspsnlECSPGSQPPSPGPATSPAPPDLDPETVRGALQEFLQEL 1518
Cdd:PTZ00121  1282 ELKKAEEKKKAD------------------------------EAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKA 1331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1519 RSAQRERDDLRTQTSAlshQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGrlSGVQAEMALQEESVRRSERERRAT 1598
Cdd:PTZ00121  1332 DAAKKKAEEAKKAAEA---AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA--AKKKAEEKKKADEAKKKAEEDKKK 1406

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1599 LDQIATLERSLQATESELRASQEKiskMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQ 1678
Cdd:PTZ00121  1407 ADELKKAAAAKKKADEAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1679 aqalqdRVDSLQRQVADSEVKAGTLQLTVERLNGA--LAKVEESEGAlrDKVRGLTEALAQSSASLNSTQDKNLHLQKA- 1755
Cdd:PTZ00121  1484 ------KADEAKKKAEEAKKKADEAKKAAEAKKKAdeAKKAEEAKKA--DEAKKAEEAKKADEAKKAEEKKKADELKKAe 1555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1756 -LTACEHDRQVLQ-----ERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAA 1829
Cdd:PTZ00121  1556 eLKKAEEKKKAEEakkaeEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKV 1635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1830 LHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRT 1909
Cdd:PTZ00121  1636 EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK 1715

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1910 LTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHRQRVRGLEE 1989
Cdd:PTZ00121  1716 KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRME 1795


                   ....*.
gi 1622834689 1990 QVSTLK 1995
Cdd:PTZ00121  1796 VDKKIK 1801
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
700-1231 1.10e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.36  E-value: 1.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  700 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQE 779
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  780 ATVAREEQERLEELRLeqevARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEqlaqlsrqlsgreqELEQARRAAQR 859
Cdd:PRK02224   278 AEEVRDLRERLEELEE----ERDDLLAEAGLDDADAEAVEARREELEDRDEELRD--------------RLEECRVAAQA 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  860 QMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLL 939
Cdd:PRK02224   340 HNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELRE 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  940 AKETLTGELAGLRQQIIAIQEKASLDKELMA--------QKLVQAER-EAQASLREQRAAHEEDLQRLQREKEAawRELE 1010
Cdd:PRK02224   420 ERDELREREAELEATLRTARERVEEAEALLEagkcpecgQPVEGSPHvETIEEDRERVEELEAELEDLEEEVEE--VEER 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1011 AERAQLQSQLQREQEELLARLEaekeelseeiaTLQQERDEGLLLAESEKQQALSLKEsEKTALSEKLMGTRHSLATISL 1090
Cdd:PRK02224   498 LERAEDLVEAEDRIERLEERRE-----------DLEELIAERRETIEEKRERAEELRE-RAAELEAEAEEKREAAAEAEE 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1091 EMERqKRDAQSRQEQDRSTVNALTSELRDLRAQLEEaVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDAR 1170
Cdd:PRK02224   566 EAEE-AREEVAELNSKLAELKERIESLERIRTLLAA-IADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEF 643

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622834689 1171 DGLRRELLEAQR------------KLRESQEGREVQRQEAGELRRSLgegaKEREALRRSNEELRAAVKKAES 1231
Cdd:PRK02224   644 DEARIEEAREDKeraeeyleqveeKLDELREERDDLQAEIGAVENEL----EELEELRERREALENRVEALEA 712
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 552-1365 1.14e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 57.29  E-value: 1.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  552 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKL-- 629
Cdd:pfam02463  197 LQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENke 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  630 -QAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAE 708
Cdd:pfam02463  277 eEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  709 ALTKAEAGRVELELSMTKLRAEEASLQDSLSK-LSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQ 787
Cdd:pfam02463  357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSaAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEE 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  788 ERLEELRLEQEVARQGLEgSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRqmealera 867
Cdd:pfam02463  437 ESIELKQGKLTEEKEELE-KQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARS-------- 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  868 aREKEALAKERAGLAVQLAAAEREGRTLSEEATrlrLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGE 947
Cdd:pfam02463  508 -GLKVLLALIKDGVGGRIISAHGRLGDLGVAVE---NYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLL 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  948 LAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAwRELEAERAQLQSQLQREQEEL 1027
Cdd:pfam02463  584 IPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA-KAKESGLRKGVSLEEGLAEKS 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1028 LARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALSE----KLMGTRHSLATISLEMERQKRDAQSRQ 1103
Cdd:pfam02463  663 EVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEElkklKLEAEELLADRVQEAQDKINEELKLLK 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1104 EQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQD--LGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQ 1181
Cdd:pfam02463  743 QKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTekLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQL 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1182 RKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEA 1261
Cdd:pfam02463  823 LIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEL 902

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1262 GELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLAlgERAEKESRRETLGLRQRLLKGEASLEVM 1341
Cdd:pfam02463  903 EEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEE--NNKEEEEERNKRLLLAKEELGKVNLMAI 980

                          810       820
                   ....*....|....*....|....
gi 1622834689 1342 RQELQVAQRKLQEQEGEFRTRERR 1365
Cdd:pfam02463  981 EEFEEKEERYNKDELEKERLEEEK 1004
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
997-1430 1.29e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.97  E-value: 1.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  997 RLQREKEAAWRELEAERAQLQSqlqREQEELLARLEAEKEELSEEIATLQQERD---------EGLLLAESEKQQALSLK 1067
Cdd:PRK02224   180 RVLSDQRGSLDQLKAQIEEKEE---KDLHERLNGLESELAELDEEIERYEEQREqaretrdeaDEVLEEHEERREELETL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1068 ESEKTALSEKLMGTrhslatislemERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAahaqEVRRLQEQAQDLGK 1147
Cdd:PRK02224   257 EAEIEDLRETIAET-----------EREREELAEEVRDLRERLEELEEERDDLLAEAGLDDA----DAEAVEARREELED 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1148 QRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVK 1227
Cdd:PRK02224   322 RDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1228 KAESERislklanEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQ 1307
Cdd:PRK02224   402 DAPVDL-------GNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDR 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1308 GRLA--LGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRerrllgsLEEARGTEKQQLDHAR 1385
Cdd:PRK02224   475 ERVEelEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRET-------IEEKRERAEELRERAA 547

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1622834689 1386 GLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAE 1430
Cdd:PRK02224   548 ELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE 592
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 547-1323 1.85e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.50  E-value: 1.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  547 DLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQrlrSANELLSReksnlahsLQVAQQQAEELRQER 626
Cdd:COG3096    285 ERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQ---AASDHLNL--------VQTALRQQEKIERYQ 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  627 EKLQAAQEELRRQRDRLEEEQEdavqdgarvrrELERSHRQLEQLEGKRSVLAKELVEVREAL----SRATLQRDMLQA- 701
Cdd:COG3096    354 EDLEELTERLEEQEEVVEEAAE-----------QLAEAEARLEAAEEEVDSLKSQLADYQQALdvqqTRAIQYQQAVQAl 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  702 EKAEVAEALTKAEAGRVELELSMTKLRAEEA-----SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQ--- 773
Cdd:COG3096    423 EKARALCGLPDLTPENAEDYLAAFRAKEQQAteevlELEQKLSVADAARRQFEKAYELVCKIAGEVERSQAWQTAREllr 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  774 ------RQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQ--AQEVLEQQLPTLRHERSRLQEQLAQLSRQLSG 845
Cdd:COG3096    503 ryrsqqALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQldAAEELEELLAELEAQLEELEEQAAEAVEQRSE 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  846 REQELEQARrAAQRQMEALERAARE-KEALAKERAGLAVQLAAAEREGRTLSEEATRLRlekealegslfEVQRQLAQLE 924
Cdd:COG3096    583 LRQQLEQLR-ARIKELAARAPAWLAaQDALERLREQSGEALADSQEVTAAMQQLLERER-----------EATVERDELA 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  925 ARREHLEAEGQALLLA-----------KETLTGELAGLRQQIIAIQEKASLDKEL--MAQKLVQAEREAQASLREQRAAH 991
Cdd:COG3096    651 ARKQALESQIERLSQPggaedprllalAERLGGVLLSEIYDDVTLEDAPYFSALYgpARHAIVVPDLSAVKEQLAGLEDC 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  992 EEDLQRLQRE----KEAAWRELEAERAQLQSQLQRE-------QEELLARleaekEELSEEIATLQQERDEgllLAESEK 1060
Cdd:COG3096    731 PEDLYLIEGDpdsfDDSVFDAEELEDAVVVKLSDRQwrysrfpEVPLFGR-----AAREKRLEELRAERDE---LAEQYA 802

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1061 QQALSLKESEKTALS-EKLMGTRHSLATIS------LEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQL--------- 1124
Cdd:COG3096    803 KASFDVQKLQRLHQAfSQFVGGHLAVAFAPdpeaelAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLqllnkllpq 882

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1125 -----EEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLE---DARDGLRRELLEAQRKLRESQEGRE---- 1192
Cdd:COG3096    883 anllaDETLADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQsdpEQFEQLQADYLQAKEQQRRLKQQIFalse 962

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1193 -VQR------QEAGEL---RRSLGEGAKER-----EALRRSNEELRAAVKKAES---ERISLKLANEDKEQKLALLEEAR 1254
Cdd:COG3096    963 vVQRrphfsyEDAVGLlgeNSDLNEKLRARleqaeEARREAREQLRQAQAQYSQynqVLASLKSSRDAKQQTLQELEQEL 1042

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834689 1255 TAVGKEAGELRTGLQEVERSRLEArrELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRE 1323
Cdd:COG3096   1043 EELGVQADAEAEERARIRRDELHE--ELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQ 1109
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1508-2003 3.43e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 3.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1508 RGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARrsvdgrlSGVQAEMALqees 1587
Cdd:PRK02224   236 RDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER-------DDLLAEAGL---- 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1588 vrrSERERRATLDQIATLERSLQATESELRASQEKIskmkaneTKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQR 1667
Cdd:PRK02224   305 ---DDADAEAVEARREELEDRDEELRDRLEECRVAA-------QAHNEEAESLREDADDLEERAEELREEAAELESELEE 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1668 SRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSA------- 1740
Cdd:PRK02224   375 AREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAlleagkc 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1741 --------------SLNSTQDKNLHLQKALTACEHDRQVLQERLDAArQALSEARKQSSSLGEQVQTLRGEVADLELQQV 1806
Cdd:PRK02224   455 pecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEELIAERRETIE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1807 EAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEK------------D 1874
Cdd:PRK02224   534 EKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAiadaedeierlrE 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1875 RVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRtLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAqqqqHLE 1954
Cdd:PRK02224   614 KREALAELNDERRERLAEKRERKRELEAEFDEAR-IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGA----VEN 688

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1622834689 1955 LQQEVERLRSAQVQTERTLEARERAHRQrvrglEEQVSTLKGQLQQELR 2003
Cdd:PRK02224   689 ELEELEELRERREALENRVEALEALYDE-----AEELESMYGDLRAELR 732
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 825-1700 4.14e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 4.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  825 LRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAvqlaaaEREGRTLSEEATRLRL 904
Cdd:TIGR02169  228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG------EEEQLRVKEKIGELEA 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  905 EKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQ--A 982
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKefA 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  983 SLREQRAAHEEDLQRLQREKEaawrELEAERAQLQSQLQREQEELlARLEAEKEELSEEIATLQQERDEGLLLAESEKQQ 1062
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREIN----ELKRELDRLQEELQRLSEEL-ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWK 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1063 ALSLKEsEKTALSEKLMGTRHSLAtislEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQlEEAVAAHAQEVRRLQEQA 1142
Cdd:TIGR02169  457 LEQLAA-DLSKYEQELYDLKEEYD----RVEKELSKLQRELAEAEAQARASEERVRGGRAV-EEVLKASIQGVHGTVAQL 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1143 QDLGKQRDSCLREAEELRTQLRLLEDARDGLRR-ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNE 1220
Cdd:TIGR02169  531 GSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAiELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVdLVEFDP 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1221 ELRAAVKKAeserISLKLANEDKEQKLALLEEAR--TAVGK--EAGELRTGLQEVERSR----LEARRELQELRRQMKML 1292
Cdd:TIGR02169  611 KYEPAFKYV----FGDTLVVEDIEAARRLMGKYRmvTLEGElfEKSGAMTGGSRAPRGGilfsRSEPAELQRLRERLEGL 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1293 DSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEqegefrtrerrllgsLEE 1372
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS---------------LEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1373 ARGTEKQQLDHARG----LELKLEATRAEAAELGLRLSaaEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRRglglgr 1448
Cdd:TIGR02169  752 EIENVKSELKELEArieeLEEDLHKLEEALNDLEARLS--HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNR------ 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1449 apspaprpvpgspardaaaggsgdglsspsnlecspgsqppspgpatspapPDLDPETVRGALQEFLQELRSAQRERDDL 1528
Cdd:TIGR02169  824 ---------------------------------------------------LTLEKEYLEKEIQELQEQRIDLKEQIKSI 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1529 RTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERS 1608
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1609 LQATESELRASQEkISKMKANETKLEGDKRRLKEVLDASESRTVKL-----ELQRRSLEGELQRSRLglsdrEAQAQALQ 1683
Cdd:TIGR02169  933 LSEIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAiqeyeEVLKRLDELKEKRAKL-----EEERKAIL 1006

                          890
                   ....*....|....*..
gi 1622834689 1684 DRVDSLQRQVADSEVKA 1700
Cdd:TIGR02169 1007 ERIEEYEKKKREVFMEA 1023
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 528-1441 4.70e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 55.18  E-value: 4.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  528 LHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRlrdKTDGAMQAQEDAQREVQRLRSANELLSREKSN 607
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQA---ETELCAEAEEMRARLAARKQELEEILHELESR 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  608 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELE----------RSHRQLEQLEGKRSV 677
Cdd:pfam01576   84 LEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEdillledqnsKLSKERKLLEERISE 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  678 LAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSA----LNESLAQDKL 753
Cdd:pfam01576  164 FTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAqiaeLRAQLAKKEE 243

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  754 DLNRLVAQLEEE---KAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERS 830
Cdd:pfam01576  244 ELQAALARLEEEtaqKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRS 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  831 RLQEQLAQLSRQL-------SGREQELEQARRAAQRQM-EALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRL 902
Cdd:pfam01576  324 KREQEVTELKKALeeetrshEAQLQEMRQKHTQALEELtEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDS 403

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  903 RLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQ-EKASLDKELM-AQKLVQAEREA 980
Cdd:pfam01576  404 EHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSkDVSSLESQLQdTQELLQEETRQ 483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  981 QASLREQRAAHEED---LQRLQREKEAAWRELEAERAQLQSQL------------------------QREQEELLARLEA 1033
Cdd:pfam01576  484 KLNLSTRLRQLEDErnsLQEQLEEEEEAKRNVERQLSTLQAQLsdmkkkleedagtlealeegkkrlQRELEALTQQLEE 563

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1034 EKEELSEEIAT---LQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTV 1110
Cdd:pfam01576  564 KAAAYDKLEKTknrLQQELDD-LLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLA 642

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1111 NALtSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQ-------RDSCLREAEELRTQLRLLED----ARDGLRRelLE 1179
Cdd:pfam01576  643 RAL-EEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNvhelersKRALEQQVEEMKTQLEELEDelqaTEDAKLR--LE 719

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1180 AQRKLRESQEGREVQ-RQEAG-ELRRSLGEGAKEREALRrsnEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAV 1257
Cdd:pfam01576  720 VNMQALKAQFERDLQaRDEQGeEKRRQLVKQVRELEAEL---EDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEA 796

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1258 GKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEAS 1337
Cdd:pfam01576  797 VKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASG 876

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1338 LEVMRQELQVAQRKLQEQEGEfrtrerrllgsLEEARGTEKQQLDHARGLELKLEATRAEaaelglrLSAAEGRAQGLEA 1417
Cdd:pfam01576  877 KSALQDEKRRLEARIAQLEEE-----------LEEEQSNTELLNDRLRKSTLQVEQLTTE-------LAAERSTSQKSES 938

                          970       980
                   ....*....|....*....|....
gi 1622834689 1418 ELARVEAQRRAAEAQLGGLRSALR 1441
Cdd:pfam01576  939 ARQQLERQNKELKAKLQEMEGTVK 962
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1768-1997 5.84e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 5.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1768 ERLDAARQALSEARkqssslgEQVQTLRgEVADLELQQVEAEGQLQQLREVLRQRQegeaaalhmVQKLQDERRLLQERL 1847
Cdd:COG4913    235 DDLERAHEALEDAR-------EQIELLE-PIRELAERYAAARERLAELEYLRAALR---------LWFAQRRLELLEAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1848 GSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLrshedtvrlsaekGRLDRTLTGAELELAEAQRQIQQL 1927
Cdd:COG4913    298 EELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRL-------------EQLEREIERLERELEERERRRARL 364

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1928 EAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHRQRVRGLEEQVSTLKGQ 1997
Cdd:COG4913    365 EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
897-1325 7.69e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.39  E-value: 7.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  897 EEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQA 976
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  977 EREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEgLLLA 1056
Cdd:COG4717    154 RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE-LEQL 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1057 ESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRD----AQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHA 1132
Cdd:COG4717    233 ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTiagvLFLVLGLLALLFLLLAREKASLGKEAEELQALPA 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1133 QEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRR-ELLEAQRKLRESQEGREVQRQEAG----ELRRSLGE 1207
Cdd:COG4717    313 LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREaEELEEELQLEELEQEIAALLAEAGvedeEELRAALE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1208 GAKEREALRRSNEELRAAVKKAESERISLKLANEDK--EQKLALLEEARTAVGKEAGELRTGLQEVER--SRLEARRELQ 1283
Cdd:COG4717    393 QAEEYQELKEELEELEEQLEELLGELEELLEALDEEelEEELEELEEELEELEEELEELREELAELEAelEQLEEDGELA 472

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 1622834689 1284 ELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETL 1325
Cdd:COG4717    473 ELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
585-1123 7.85e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.54  E-value: 7.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  585 EDAQREVQRLRSANELLSREKSNLAHsLQVAQQQAEELRQEREKLQAAQEELRRQRD-RLEEEQEDAVQDGARVRRELER 663
Cdd:COG4913    228 DALVEHFDDLERAHEALEDAREQIEL-LEPIRELAERYAAARERLAELEYLRAALRLwFAQRRLELLEAELEELRAELAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  664 SHRQLEQLEGKRSVLAKELVEVREALSRATLQR-DMLQAEKAEVAEALTKAEAGRVELElsmTKLRAEEASLQDSLSKLS 742
Cdd:COG4913    307 LEAELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARLE---ALLAALGLPLPASAEEFA 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  743 ALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELR----LEQEVARQGLEGSLRVAEQA---- 814
Cdd:COG4913    384 ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEAElpfv 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  815 -------------QEVLEQQLPTLR--------------------HERSRLQEQLAQLSRQLSGREQELEQ--------- 852
Cdd:COG4913    464 gelievrpeeerwRGAIERVLGGFAltllvppehyaaalrwvnrlHLRGRLVYERVRTGLPDPERPRLDPDslagkldfk 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  853 ---ARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGslFEVQRQLAQLEARREH 929
Cdd:COG4913    544 phpFRAWLEAELGRRFDYVCVDSPEELRRHPRAITRAGQVKGNGTRHEKDDRRRIRSRYVLG--FDNRAKLAALEAELAE 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  930 LEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDkelmaqklvqAEREAQASLREQRAAHEEDLQRLQREKeAAWREL 1009
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRLAEYS----------WDEIDVASAEREIAELEAELERLDASS-DDLAAL 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1010 EAERAQLQSQLQrEQEELLARLEAEKEELSEEIATLQQERDEglllAESEKQQALSLKESEKTALSEKlmgtRHSLATIS 1089
Cdd:COG4913    691 EEQLEELEAELE-ELEEELDELKGEIGRLEKELEQAEEELDE----LQDRLEAAEDLARLELRALLEE----RFAAALGD 761

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1622834689 1090 LEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQ 1123
Cdd:COG4913    762 AVERELRENLEERIDALRARLNRAEEELERAMRA 795
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1118-1697 1.01e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.15  E-value: 1.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1118 RDLRAQLEEAVAAHaQEVRRLQEQAQDLGKQRDSClREAEELRTQLRLLEDARDGLRreLLEAQRKLRESQEGREVQRQE 1197
Cdd:COG4913    228 DALVEHFDDLERAH-EALEDAREQIELLEPIRELA-ERYAAARERLAELEYLRAALR--LWFAQRRLELLEAELEELRAE 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1198 AGELRRSLGEGAKEREALRRSNEELRAAVKKAESERI-SLKLANEDKEQKLALLEEARTAVGKEAGELR----TGLQEVE 1272
Cdd:COG4913    304 LARLEAELERLEARLDALREELDELEAQIRGNGGDRLeQLEREIERLERELEERERRRARLEALLAALGlplpASAEEFA 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1273 RSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLA--LGERAEKESRRETLGLRQRLLKGE--ASLEVMRQELQVA 1348
Cdd:COG4913    384 ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRelEAEIASLERRKSNIPARLLALRDAlaEALGLDEAELPFV 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1349 QRKLQEQEGE-------------FRTR-------ERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAA 1408
Cdd:COG4913    464 GELIEVRPEEerwrgaiervlggFALTllvppehYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFK 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1409 EGRAQG-LEAELAR---------VEAQRRAAEA-QLGGLRSALRRGLGLGRAPSPAPRPVPGSPARDAaaggsgdglssp 1477
Cdd:COG4913    544 PHPFRAwLEAELGRrfdyvcvdsPEELRRHPRAiTRAGQVKGNGTRHEKDDRRRIRSRYVLGFDNRAK------------ 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1478 snlecspgsqppspgpatspappdldpetvrgaLQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERdhatlRARQLQ 1557
Cdd:COG4913    612 ---------------------------------LAALEAELAELEEELAEAEERLEALEAELDALQERR-----EALQRL 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1558 KAVAESEEARRSVDGRLSGVQAEMAlqeesvrrserERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDK 1637
Cdd:COG4913    654 AEYSWDEIDVASAEREIAELEAELE-----------RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKEL 722

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834689 1638 RRLKEVLDASESR---TVKLELQRRSLEGELQRSRLGLSDREAQ-AQALQDRVDSLQRQVADSE 1697
Cdd:COG4913    723 EQAEEELDELQDRleaAEDLARLELRALLEERFAAALGDAVERElRENLEERIDALRARLNRAE 786
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1597-1821 2.29e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 2.29e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1597 ATLDQIATLERSLQATE---------SELRASQEKISKMKANETKLEGDKRRLKevLDASESRTVKLELQRRSLEGELQR 1667
Cdd:COG4913    229 ALVEHFDDLERAHEALEdareqiellEPIRELAERYAAARERLAELEYLRAALR--LWFAQRRLELLEAELEELRAELAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1668 SRLGLSDREAQAQALQDRVDSLQRQVADSEVKA-GTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQ 1746
Cdd:COG4913    307 LEAELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALR 386

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622834689 1747 DknlhlqkaltACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQ 1821
Cdd:COG4913    387 A----------EAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAE 451
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 833-1080 2.94e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 2.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  833 QEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGS 912
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  913 LFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKasldkelmAQKLVQAEREAQASLREQRAAHE 992
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA--------RREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  993 EDLQRLQREKEaawrELEAERAQLQsQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKT 1072
Cdd:COG4942    171 AERAELEALLA----ELEEERAALE-ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245


                   ....*...
gi 1622834689 1073 ALSEKLMG 1080
Cdd:COG4942    246 AGFAALKG 253
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
549-822 3.62e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 51.44  E-value: 3.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  549 LGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREK 628
Cdd:COG4372     40 LDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEE 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  629 LQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAE 708
Cdd:COG4372    120 LQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKE 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  709 ALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQE 788
Cdd:COG4372    200 EELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELE 279

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1622834689  789 RLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQL 822
Cdd:COG4372    280 IAALELEALEEAALELKLLALLLNLAALSLIGAL 313
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 74-445 4.36e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 4.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   74 ASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQTLRLESGELETQEPRGLVRQSVELRR-QLQEEQ 152
Cdd:COG1196    316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELlEALRAA 395

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  153 ASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRNTEHSQDLESALIRLEEEQQRSASL 232
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  233 AQVNAMLREQLDQA---------------------------------------------------GLANQALSEDIRKVT 261
Cdd:COG1196    476 EAALAELLEELAEAaarllllleaeadyegflegvkaalllaglrglagavavligveaayeaalEAALAAALQNIVVED 555

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  262 SDWARSRKELEQREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLG 341
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  342 LSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVERLQKQNLEKDQVNK 421
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715

                          410       420
                   ....*....|....*....|....
gi 1622834689  422 DLTEKLEALESLRLQEQAALETED 445
Cdd:COG1196    716 RLEEELEEEALEEQLEAEREELLE 739
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 535-1202 4.74e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.88  E-value: 4.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  535 VQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDG--AMQAQEDAQREVQRLRSANELLSR--------- 603
Cdd:COG3096    443 LAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEveRSQAWQTARELLRRYRSQQALAQRlqqlraqla 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  604 EKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELV 683
Cdd:COG3096    523 ELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAP 602

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  684 EVREALSRATLQRDMLQAE---KAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESlaqDKLDLNRL-- 758
Cdd:COG3096    603 AWLAAQDALERLREQSGEAladSQEVTAAMQQLLEREREATVERDELAARKQALESQIERLSQPGGA---EDPRLLALae 679

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  759 ----------------------------------VAQLEEEKAALQGRQRQAEQ----EATVAREEQERLEELRLEQEVA 800
Cdd:COG3096    680 rlggvllseiyddvtledapyfsalygparhaivVPDLSAVKEQLAGLEDCPEDlyliEGDPDSFDDSVFDAEELEDAVV 759

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  801 RQGLEGSLRVAEQAQEVL------EQQLPTLRHERSRLQEQLAQLSRqlsgreqeleqARRAAQRQMEALERAAREKEAL 874
Cdd:COG3096    760 VKLSDRQWRYSRFPEVPLfgraarEKRLEELRAERDELAEQYAKASF-----------DVQKLQRLHQAFSQFVGGHLAV 828

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  875 AKEraglavqlAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEA-EGQALLLAKETLTGELAGLRQ 953
Cdd:COG3096    829 AFA--------PDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKlLPQANLLADETLADRLEELRE 900

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  954 QIIAIQEkasldkelmAQKLVQAEREAQASLREQRAAHEEDLQRLQrEKEAAWRELEAERAQLQSQLQrEQEELLARLEA 1033
Cdd:COG3096    901 ELDAAQE---------AQAFIQQHGKALAQLEPLVAVLQSDPEQFE-QLQADYLQAKEQQRRLKQQIF-ALSEVVQRRPH 969

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1034 EKEELSEEIATLQQERDEGLllaesekQQALSLKESEKTALSEKLMGTRHSLATISLEMErqkrDAQSRQEQDRSTVNAL 1113
Cdd:COG3096    970 FSYEDAVGLLGENSDLNEKL-------RARLEQAEEARREAREQLRQAQAQYSQYNQVLA----SLKSSRDAKQQTLQEL 1038

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1114 TSELRDLRAQL-EEAVAAHAQEVRRLQEQA-------QDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEA----- 1180
Cdd:COG3096   1039 EQELEELGVQAdAEAEERARIRRDELHEELsqnrsrrSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAkagwc 1118

                          730       740
                   ....*....|....*....|....*....
gi 1622834689 1181 --QRKLRESQEGREVQR-----QEAGELR 1202
Cdd:COG3096   1119 avLRLARDNDVERRLHRrelayLSADELR 1147
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 542-1100 6.19e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 51.26  E-value: 6.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  542 YEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSReksnlahSLQVAQQQAEE 621
Cdd:pfam05483  221 HEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDE-------NLKELIEKKDH 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  622 LRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRaTLQRDMLQA 701
Cdd:pfam05483  294 LTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEE-LLRTEQQRL 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  702 EKAEVAEALTKAEAGRVELELS-MTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEA 780
Cdd:pfam05483  373 EKNEDQLKIITMELQKKSSELEeMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEI 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  781 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQ 860
Cdd:pfam05483  453 HDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERM 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  861 MEALERAARE-----------KEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREH 929
Cdd:pfam05483  533 LKQIENLEEKemnlrdelesvREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEE 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  930 LEAEGQALllaKETLTGELAGLRQQIIAIQeKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAwrel 1009
Cdd:pfam05483  613 LHQENKAL---KKKGSAENKQLNAYEIKVN-KLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIA---- 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1010 eAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALSE---KLMGTRHSLA 1086
Cdd:pfam05483  685 -DEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNikaELLSLKKQLE 763

                          570
                   ....*....|....
gi 1622834689 1087 TISLEMERQKRDAQ 1100
Cdd:pfam05483  764 IEKEEKEKLKMEAK 777
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1766-1939 7.54e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 7.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1766 LQERLDAARQALSEARKQSSSLgeQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQ- 1844
Cdd:COG4913    260 LAERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGg 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1845 ERLGSLQRALAQLEAEKREVERSALRLEKD----RVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEA 1920
Cdd:COG4913    338 DRLEQLEREIERLERELEERERRRARLEALlaalGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417

                          170
                   ....*....|....*....
gi 1622834689 1921 QRQIQQLEAQVVVLEQSHS 1939
Cdd:COG4913    418 RRELRELEAEIASLERRKS 436
mukB PRK04863
chromosome partition protein MukB;
561-1256 7.58e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 51.50  E-value: 7.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  561 SERRALEEQLQRLRdktdgamQAQEDAQREVQRLRSANELLSReksnlahslqvAQQQAEELRQEREKLQAAQEELRRQR 640
Cdd:PRK04863   506 REQRHLAEQLQQLR-------MRLSELEQRLRQQQRAERLLAE-----------FCKRLGKNLDDEDELEQLQEELEARL 567

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  641 DRLEEEQEDAVQDGARVRRELErshrQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVEL 720
Cdd:PRK04863   568 ESLSESVSEARERRMALRQQLE----QLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLEREREL 643

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  721 ELSMTKLRAEEASLQDSLSKLSALNESLAQDkldLNRL------------------------------------VAQLEE 764
Cdd:PRK04863   644 TVERDELAARKQALDEEIERLSQPGGSEDPR---LNALaerfggvllseiyddvsledapyfsalygparhaivVPDLSD 720

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  765 EKAALQGRQRQAEQ----EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVL------EQQLPTLRHERSRLQE 834
Cdd:PRK04863   721 AAEQLAGLEDCPEDlyliEGDPDSFDDSVFSVEELEKAVVVKIADRQWRYSRFPEVPLfgraarEKRIEQLRAEREELAE 800

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  835 QLAQLSRQlsgreqeleqaRRAAQRQMEALERAAREKEALAKErAGLAVQLAAAEREGRTLSEEATRLRLEkealegslf 914
Cdd:PRK04863   801 RYATLSFD-----------VQKLQRLHQAFSRFIGSHLAVAFE-ADPEAELRQLNRRRVELERALADHESQ--------- 859

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  915 eVQRQLAQLEARREHLEA----EGQALLLAKETLTGELAGLRQQIIAIQE-KASLDKElmAQKLVQAEREAqASLREQra 989
Cdd:PRK04863   860 -EQQQRSQLEQAKEGLSAlnrlLPRLNLLADETLADRVEEIREQLDEAEEaKRFVQQH--GNALAQLEPIV-SVLQSD-- 933

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  990 ahEEDLQRLQREKEAAwrelEAERAQLQSQLqREQEELLARLEAEKEELSEEIATLQQERDEGLllaesekQQALSLKES 1069
Cdd:PRK04863   934 --PEQFEQLKQDYQQA----QQTQRDAKQQA-FALTEVVQRRAHFSYEDAAEMLAKNSDLNEKL-------RQRLEQAEQ 999

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1070 EKTALSEKLMGTRHSLAtislEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAhaqevrRLQEQAQDLGKQR 1149
Cdd:PRK04863  1000 ERTRAREQLRQAQAQLA----QYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEE------RARARRDELHARL 1069

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1150 DSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRR-----SNEELRA 1224
Cdd:PRK04863  1070 SANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAGWCAVLRLVKDNGVERRLHRRelaylSADELRS 1149

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 1622834689 1225 AVKKAESeriSLKLA---NEDKEQKLALLEEARTA 1256
Cdd:PRK04863  1150 MSDKALG---ALRLAvadNEHLRDVLRLSEDPKRP 1181
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1093-1311 7.87e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 7.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1093 ERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDG 1172
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1173 LRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEE 1252
Cdd:COG4942    106 LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834689 1253 ARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLA 1311
Cdd:COG4942    186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 811-1355 8.40e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.12  E-value: 8.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  811 AEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAglavqlAAAER 890
Cdd:TIGR00618  210 TPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAV------LEETQ 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  891 EGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEgqalllaketLTGELAGLRQQIIAIQEKASLDKELMA 970
Cdd:TIGR00618  284 ERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL----------LMKRAAHVKQQSSIEEQRRLLQTLHSQ 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  971 QKLVQAEREAQASLREQRAAHEEDLQRL--QREKEAAWRELEAERAQLQSQLQREQEELLARLeaekeelseeiatlQQE 1048
Cdd:TIGR00618  354 EIHIRDAHEVATSIREISCQQHTLTQHIhtLQQQKTTLTQKLQSLCKELDILQREQATIDTRT--------------SAF 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1049 RDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAV 1128
Cdd:TIGR00618  420 RDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLEL 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1129 AAHAQEVR------------------------RLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKL 1184
Cdd:TIGR00618  500 QEEPCPLCgscihpnparqdidnpgpltrrmqRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCD 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1185 RESQEGREVQRQEAGELRRSLGEGAKEREALR-RSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGE 1263
Cdd:TIGR00618  580 NRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAcEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQER 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1264 LRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQ 1343
Cdd:TIGR00618  660 VREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARED 739

                          570
                   ....*....|..
gi 1622834689 1344 ELQVAQRKLQEQ 1355
Cdd:TIGR00618  740 ALNQSLKELMHQ 751
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
76-258 9.33e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.79  E-value: 9.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   76 LLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQTLRLESGELETQEPRGLVRQSVELRRQLQEEQASY 155
Cdd:COG3206    207 LVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARY 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  156 RRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRNTEHSQDLESALIRLEEEQQRSASLAQV 235
Cdd:COG3206    287 TPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVAREL 366

                          170       180
                   ....*....|....*....|...
gi 1622834689  236 NAMLREQLDQAGLANQALSEDIR 258
Cdd:COG3206    367 YESLLQRLEEARLAEALTVGNVR 389
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 965-1299 9.38e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.89  E-value: 9.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  965 DKELMAQKLVQAEREAQASLREQRAAHEE-DLQRLQREKEAAWRELEAERAQLQSQLQREQEellarlEAEKEELSEEIA 1043
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKmEQERLRQEKEEKAREVERRRKLEEAEKARQAE------MDRQAAIYAEQE 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1044 TLQQERDEGLLLAESEKQQalslKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDlraq 1123
Cdd:pfam17380  341 RMAMERERELERIRQEERK----RELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQ---- 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1124 leeavaahaqevRRLQEQAQDLGKQRdsclREAEELRT-QLRLLEDARDglrRELLEAQRKLRESQEGREVQRQEAGELR 1202
Cdd:pfam17380  413 ------------RKIQQQKVEMEQIR----AEQEEARQrEVRRLEEERA---REMERVRLEEQERQQQVERLRQQEEERK 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1203 RSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLAL-LEEARTAVGKEAGELRTGLQEVERSRLEARRE 1281
Cdd:pfam17380  474 RKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKeMEERQKAIYEEERRREAEEERRKQQEMEERRR 553

                          330
                   ....*....|....*...
gi 1622834689 1282 LQElrrQMKMLDSENTRL 1299
Cdd:pfam17380  554 IQE---QMRKATEERSRL 568
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
645-1290 9.81e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 9.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  645 EEQEDAVQDGARVRRELERSHRQLEQLegkrsvlakelvevreaLSRATLQRDMLQAEKAEVAEALTKAEagrvELELSM 724
Cdd:PRK03918   158 DDYENAYKNLGEVIKEIKRRIERLEKF-----------------IKRTENIEELIKEKEKELEEVLREIN----EISSEL 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  725 TKLRAEEASLQDSLSKLSALNESLAQdkldLNRLVAQLEEEKAALQGRQRQAEQEatvareeqerleelrleqevaRQGL 804
Cdd:PRK03918   217 PELREELEKLEKEVKELEELKEEIEE----LEKELESLEGSKRKLEEKIRELEER---------------------IEEL 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  805 EGSLRVAEQAQEVLE--QQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLA 882
Cdd:PRK03918   272 KKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELE 351

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  883 VQLAAAEREGRTLsEEATRL-----RLEKEALEGSLFEVQRQLAQLEARREHLEAEgqalllaKETLTGELAGLRqqiia 957
Cdd:PRK03918   352 KRLEELEERHELY-EEAKAKkeeleRLKKRLTGLTPEKLEKELEELEKAKEEIEEE-------ISKITARIGELK----- 418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  958 iQEKASLDKELMaqKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELlarleAEKEE 1037
Cdd:PRK03918   419 -KEIKELKKAIE--ELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELREL-----EKVLK 490

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1038 LSEEIATLQQERDEglLLAESEKQQALSLKESEKTAlsEKLMGTRHSLATISLEMERQKRDAQSRQEqdrstvnaLTSEL 1117
Cdd:PRK03918   491 KESELIKLKELAEQ--LKELEEKLKKYNLEELEKKA--EEYEKLKEKLIKLKGEIKSLKKELEKLEE--------LKKKL 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1118 RDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELleaqRKLRESQEGREVQRQE 1197
Cdd:PRK03918   559 AELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREE----KELKKLEEELDKAFEE 634

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1198 AGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANedKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLE 1277
Cdd:PRK03918   635 LAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAG--LRAELEELEKRREEIKKTLEKLKEELEEREKAKKE 712

                          650
                   ....*....|....*....
gi 1622834689 1278 ------ARRELQELRRQMK 1290
Cdd:PRK03918   713 leklekALERVEELREKVK 731
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
591-1029 1.09e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 1.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  591 VQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQ 670
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  671 LEgkrsvLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASL----QDSLSKLSALNE 746
Cdd:COG4717    128 LP-----LYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLslatEEELQDLAEELE 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  747 SLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVA---------------RQGLEGSLRVA 811
Cdd:COG4717    203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAallallglggsllslILTIAGVLFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  812 EQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAERE 891
Cdd:COG4717    283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  892 GRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEaegqALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQ 971
Cdd:COG4717    363 LQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKE----ELEELEEQLEELLGELEELLEALDEEELEEELEELE 438

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834689  972 KLVQAEREAQASLREQRAAHEEDLQRLQREKEAAwrELEAERAQLQSQLQREQEELLA 1029
Cdd:COG4717    439 EELEELEEELEELREELAELEAELEQLEEDGELA--ELLQELEELKAELRELAEEWAA 494
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1115-1351 1.37e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1115 SELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQ 1194
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1195 RQEAGELrrslgegakerealrrsneeLRAAVKKAESERISLKLANEDKEQ---KLALLEEARTAVGKEAGELRTGLQEV 1271
Cdd:COG4942    103 KEELAEL--------------------LRALYRLGRQPPLALLLSPEDFLDavrRLQYLKYLAPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1272 ERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRK 1351
Cdd:COG4942    163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1091-1424 1.79e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.06  E-value: 1.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1091 EMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEaVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDAR 1170
Cdd:PRK03918   190 NIEELIKEKEKELEEVLREINEISSELPELREELEK-LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERI 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1171 DGLRRELLEAQRKLRESQEGREVQRQ--EAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERislklanEDKEQKLA 1248
Cdd:PRK03918   269 EELKKEIEELEEKVKELKELKEKAEEyiKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL-------EEKEERLE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1249 LLEEARTAVGKEAGELRTGLQEVERSRL------------------EARRELQELRRQMKMLDSENTRLGRELAELQGRL 1310
Cdd:PRK03918   342 ELKKKLKELEKRLEELEERHELYEEAKAkkeelerlkkrltgltpeKLEKELEELEKAKEEIEEEISKITARIGELKKEI 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1311 ALGERA--EKESRRETLGLRQRLLKGEASLEVMRQ------ELQVAQRKLQEQEGEFRTRERRLLGSLEEARG--TEKQQ 1380
Cdd:PRK03918   422 KELKKAieELKKAKGKCPVCGRELTEEHRKELLEEytaelkRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKEL 501

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622834689 1381 LDHARGLELKLEATRAEAAE--------LGLRLSAAEGRAQGLEAELARVEA 1424
Cdd:PRK03918   502 AEQLKELEEKLKKYNLEELEkkaeeyekLKEKLIKLKGEIKSLKKELEKLEE 553
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1731-1937 2.00e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1731 LTEALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEG 1810
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1811 QLQQLREVLRQRQEGEAAALHMVQKLQDERRLL----QERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVE 1886
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622834689 1887 REKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQS 1937
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
626-1051 2.16e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 2.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  626 REKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAe 705
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ- 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  706 vaealtkaeagrvelelsmtklraeeasLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVARE 785
Cdd:COG4717    127 ----------------------------LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEE 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  786 EQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSgREQELEQARRAAQRQMEALE 865
Cdd:COG4717    179 LEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELE-AAALEERLKEARLLLLIAAA 257

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  866 RAAREKEALAKERAGLAVQLAAAEREGrTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLT 945
Cdd:COG4717    258 LLALLGLGGSLLSLILTIAGVLFLVLG-LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSP 336

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  946 GELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE 1025
Cdd:COG4717    337 EELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLG 416

                          410       420
                   ....*....|....*....|....*..
gi 1622834689 1026 ELLARLEAEKEEL-SEEIATLQQERDE 1051
Cdd:COG4717    417 ELEELLEALDEEElEEELEELEEELEE 443
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 549-1128 2.44e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.84  E-value: 2.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  549 LGTLRKQLSDSESERRALEEQLQRLRDktDGAMQAQEDAQREVQrLRSANELLSREKSNLAHSLQVAQQQAEELRQEREK 628
Cdd:pfam12128  310 LSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLPS-WQSELENLEERLKALTGKHQDVTAKYNRRRSKIKE 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  629 LQAAqeELRRQRDRLEEEQEDAVQDGARVRRELERSHRQL-EQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKaeva 707
Cdd:pfam12128  387 QNNR--DIAGIKDKLAKIREARDRQLAVAEDDLQALESELrEQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATP---- 460

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  708 EALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEA------- 780
Cdd:pfam12128  461 ELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAgtllhfl 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  781 -TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE------------------------------VLEQQLPTLRHER 829
Cdd:pfam12128  541 rKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGElnlygvkldlkridvpewaaseeelrerldKAEEALQSAREKQ 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  830 SRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALA-KERAGLAVQLAAAEREGRTLSEEATRLRLEKEA 908
Cdd:pfam12128  621 AAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKdKKNKALAERKDSANERLNSLEAQLKQLDKKHQA 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  909 LEGSLFEVQRQL--AQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQE--KASLDK----ELMAQKLVQAEREA 980
Cdd:pfam12128  701 WLEEQKEQKREArtEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETwyKRDLASlgvdPDVIAKLKREIRTL 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  981 QASLrEQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDeglllaESEK 1060
Cdd:pfam12128  781 ERKI-ERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERK------ASEK 853

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834689 1061 QQALslkesektaLSEKLMGTRHSLATISlemeRQKRDAQSRQEQ-DRSTVNALTSELRDLRAQLEEAV 1128
Cdd:pfam12128  854 QQVR---------LSENLRGLRCEMSKLA----TLKEDANSEQAQgSIGERLAQLEDLKLKRDYLSESV 909
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 875-1231 2.49e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.57  E-value: 2.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  875 AKERAGLAVQLAAAEREgrtLSEEATRLRLEKEALEgslfEVQRQLAQLEARREHLEAEGQAlllAKETLTGELAGLRQQ 954
Cdd:COG3096    277 ANERRELSERALELRRE---LFGARRQLAEEQYRLV----EMARELEELSARESDLEQDYQA---ASDHLNLVQTALRQQ 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  955 --IIAIQEK-ASLDKELMAQKLVQAER-EAQASLREQRAAHEEDLQRLQREKEAAWRELEAE--RA-QLQSQLQR--EQE 1025
Cdd:COG3096    347 ekIERYQEDlEELTERLEEQEEVVEEAaEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQqtRAiQYQQAVQAleKAR 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1026 ELLARLEAEKEELSEEIATLQ---QERDEGLLLAEsekqQALSLKESEKTALSEKLmgtrHSLATISLEMERQKRDAQSR 1102
Cdd:COG3096    427 ALCGLPDLTPENAEDYLAAFRakeQQATEEVLELE----QKLSVADAARRQFEKAY----ELVCKIAGEVERSQAWQTAR 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1103 Q--EQDRSTVnALTSELRDLRAQLEEAVAAHAQEvRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEA 1180
Cdd:COG3096    499 EllRRYRSQQ-ALAQRLQQLRAQLAELEQRLRQQ-QNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEA 576

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622834689 1181 QRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAES 1231
Cdd:COG3096    577 VEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQE 627
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 552-852 2.69e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.25  E-value: 2.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  552 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQA 631
Cdd:TIGR04523  347 LKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEK 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  632 AQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKE-------LVEVREALSRATLQRDMLQAEKA 704
Cdd:TIGR04523  427 EIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSinkikqnLEQKQKELKSKEKELKKLNEEKK 506

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  705 EVAEALTKAEAGRVELELSMTKLRAEEASLQdslSKLSALNESLAQDKLDLNRlvAQLEEEKAALQGRQRQAEQEATVAR 784
Cdd:TIGR04523  507 ELEEKVKDLTKKISSLKEKIEKLESEKKEKE---SKISDLEDELNKDDFELKK--ENLEKEIDEKNKEIEELKQTQKSLK 581

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834689  785 EEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQ 852
Cdd:TIGR04523  582 KKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQ 649
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1608-1829 2.90e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1608 SLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVD 1687
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1688 SLQRQVADSEVKAGTLQLTVERLngALAKVEESEGALR--DKVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHDRQV 1765
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLA--LLLSPEDFLDAVRrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834689 1766 LQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAA 1829
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1505-1873 3.83e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.88  E-value: 3.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1505 ETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQ 1584
Cdd:PRK02224   331 EECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNA 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1585 EESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Cdd:PRK02224   411 EDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEE 490

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1665 LQR------SRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRD---KVRGLTEAL 1735
Cdd:PRK02224   491 VEEveerleRAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREaaaEAEEEAEEA 570

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1736 AQSSASLNSTQDKN----------LHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQq 1805
Cdd:PRK02224   571 REEVAELNSKLAELkeriesleriRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIE- 649

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834689 1806 vEAEGQLQQLREVLRQRQEgeaaalhMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEK 1873
Cdd:PRK02224   650 -EAREDKERAEEYLEQVEE-------KLDELREERDDLQAEIGAVENELEELEELRERREALENRVEA 709
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 801-1030 4.04e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 4.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  801 RQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLsgreQELEQARRAAQRQMEALERAAREKEA-LAKERA 879
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI----RALEQELAALEAELAELEKEIAELRAeLEAQKE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  880 GLAVQLAAAEREGRTLSEEatrlrlekealegsLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQ 959
Cdd:COG4942    105 ELAELLRALYRLGRQPPLA--------------LLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622834689  960 EKASLDKELMAQKlvQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLAR 1030
Cdd:COG4942    171 AERAELEALLAEL--EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
830-1129 5.24e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.97  E-value: 5.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  830 SRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEAL 909
Cdd:COG4372     34 RKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEEL 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  910 EGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRA 989
Cdd:COG4372    114 QEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEAN 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  990 AHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKES 1069
Cdd:COG4372    194 RNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDT 273

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1070 EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVA 1129
Cdd:COG4372    274 EEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALA 333
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
527-653 5.48e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 5.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  527 ALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKS 606
Cdd:COG4913    665 SAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR 744

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622834689  607 NLAHSL---QVAQQQAEELRQE-REKLQAAQEELRRQRDRLEEEQEDAVQD 653
Cdd:COG4913    745 LELRALleeRFAAALGDAVERElRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1505-1997 5.87e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 5.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1505 ETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQ 1584
Cdd:TIGR02169  304 ASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAET 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1585 EESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAAD 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTV-----------ERLNGAL--------------AKVEE 1719
Cdd:TIGR02169  464 LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVrggraveevlkASIQGVHgtvaqlgsvgeryaTAIEV 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1720 SEGALRDKVRGLTEALAQSSAS--------------LNSTQDKNLHLQK---------ALTACEHDRQ------------ 1764
Cdd:TIGR02169  544 AAGNRLNNVVVEDDAVAKEAIEllkrrkagratflpLNKMRDERRDLSIlsedgvigfAVDLVEFDPKyepafkyvfgdt 623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1765 VLQERLDAARQALSEARkqssslgeqVQTLRGEVadLELQQVEAEGQLQQLREVLRQRQEGEAAAL--HMVQKLQDERRL 1842
Cdd:TIGR02169  624 LVVEDIEAARRLMGKYR---------MVTLEGEL--FEKSGAMTGGSRAPRGGILFSRSEPAELQRlrERLEGLKRELSS 692

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1843 LQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQR 1922
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEE 772

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622834689 1923 QIQQLEAQVVVLEQ--SHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAhRQRVRGLEEQVSTLKGQ 1997
Cdd:TIGR02169  773 DLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL-EKEIQELQEQRIDLKEQ 848
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1549-1788 6.29e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 6.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1549 ATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKA 1628
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1629 NETKLEGDKRRLKEVLdasESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVE 1708
Cdd:COG4942     91 EIAELRAELEAQKEEL---AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1709 RLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLG 1788
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
527-954 6.37e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 6.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  527 ALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQ------RLRSANEL 600
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAElaelpeRLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  601 LSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAK 680
Cdd:COG4717    155 LEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEN 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  681 ELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVA 760
Cdd:COG4717    235 ELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALE 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  761 QLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARqglEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLS 840
Cdd:COG4717    315 ELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLRE---AEELEEELQLEELEQEIAALLAEAGVEDEEELRAAL 391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  841 RQLSgREQELEQARRAAQRQMEALERAARE------KEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALE--GS 912
Cdd:COG4717    392 EQAE-EYQELKEELEELEEQLEELLGELEEllealdEEELEEELEELEEELEELEEELEELREELAELEAELEQLEedGE 470

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 1622834689  913 LFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQ 954
Cdd:COG4717    471 LAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 959-1298 6.38e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.20  E-value: 6.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  959 QEKASLDKEL-MAQKLVQAEREAQASLREQRAAHEEdlqrlqREKEAAWRELEAERAQLQSQlQREQEELLARLEAEKEE 1037
Cdd:pfam17380  303 QEKEEKAREVeRRRKLEEAEKARQAEMDRQAAIYAE------QERMAMERERELERIRQEER-KRELERIRQEEIAMEIS 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1038 LSEEIATLQQERdeglllaeseKQQALSLKESEKTALSEKLmgtrhslatisLEMERQKRDAQSRQEQDRstvnaltsel 1117
Cdd:pfam17380  376 RMRELERLQMER----------QQKNERVRQELEAARKVKI-----------LEEERQRKIQQQKVEMEQ---------- 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1118 rdLRAQLEEavaAHAQEVRRLQEQAQdlgKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQR-- 1195
Cdd:pfam17380  425 --IRAEQEE---ARQREVRRLEEERA---REMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRki 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1196 --QEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISlklanEDKEQKLALLEEARTAvgkeagELRTGLQEVER 1273
Cdd:pfam17380  497 leKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREA-----EEERRKQQEMEERRRI------QEQMRKATEER 565

                          330       340
                   ....*....|....*....|....*
gi 1622834689 1274 SRLEARRELQELRRQMKmlDSENTR 1298
Cdd:pfam17380  566 SRLEAMEREREMMRQIV--ESEKAR 588
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1755-1975 7.74e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 7.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1755 ALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQ 1834
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1835 KLQDERRLLQERLGSLQRALAQLEAEKR-----------EVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK 1903
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPlalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622834689 1904 GRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEA 1975
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 528-843 8.32e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.71  E-value: 8.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  528 LHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSN 607
Cdd:TIGR04523  365 LEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKD 444

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  608 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQdgarvrrELERSHRQLEQLEGKRSVLAKELVEVRE 687
Cdd:TIGR04523  445 LTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK-------ELKSKEKELKKLNEEKKELEEKVKDLTK 517

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  688 ALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTK--LRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEE 765
Cdd:TIGR04523  518 KISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKenLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKE 597

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834689  766 KAALqgRQRQAEQEATVAReeqerleelrleqevarqgLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQL 843
Cdd:TIGR04523  598 KKDL--IKEIEEKEKKISS-------------------LEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 511-750 9.96e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  511 PSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQRE 590
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  591 VQRLRSAnelLSREKSNLAHSLQVAQQQAeelRQEREKLQAAQEELRRQRDRLEEEQEDAVQDgarvRRELERSHRQLEQ 670
Cdd:COG4942     92 IAELRAE---LEAQKEELAELLRALYRLG---RQPPLALLLSPEDFLDAVRRLQYLKYLAPAR----REQAEELRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  671 LEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQ 750
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 80-630 1.00e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.81  E-value: 1.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   80 QEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQTLRLESGELET--QEPRGLVRQSVELRRQLQEEQASYRR 157
Cdd:pfam15921  309 RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEarTERDQFSQESGNLDDQLQKLLADLHK 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  158 KLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLE--RSGELEQQRLRNTEHSQDLESALIR-----LEEEQQRSA 230
Cdd:pfam15921  389 REKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEvqRLEALLKAMKSECQGQMERQMAAIQgknesLEKVSSLTA 468

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  231 SLAQVNAMLREQLDQAGLANQALSEDIRKVtSDWARSRKELEqreaawrREEESFNAYFSNEHSRLLLLWRQVVGFRRLV 310
Cdd:pfam15921  469 QLESTKEMLRKVVEELTAKKMTLESSERTV-SDLTASLQEKE-------RAIEATNAEITKLRSRVDLKLQELQHLKNEG 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  311 SEVK-MFTERDLLQLggELARTSRAVQEAGLGLSTGLRLA--ESRTEAALEKQallQAQLEEQLRDKVLREKDLAQQQMQ 387
Cdd:pfam15921  541 DHLRnVQTECEALKL--QMAEKDKVIEILRQQIENMTQLVgqHGRTAGAMQVE---KAQLEKEINDRRLELQEFKILKDK 615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  388 SDLDKADLSARVTELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRLQEQAALE--TEDGEGLQQTLRDLAQAV-LSDS 464
Cdd:pfam15921  616 KDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNslSEDYEVLKRNFRNKSEEMeTTTN 695

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  465 ESGVQLSGSERTADASDGSLRGLSGqrtpspprrsspgrgrsprrgpspacSDSSTLALIHSAlhkrQLQVQDMRGRYEA 544
Cdd:pfam15921  696 KLKMQLKSAQSELEQTRNTLKSMEG--------------------------SDGHAMKVAMGM----QKQITAKRGQIDA 745

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  545 SQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNL-----AHSLQVAQQQA 619
Cdd:pfam15921  746 LQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMevaldKASLQFAECQD 825

                          570
                   ....*....|.
gi 1622834689  620 EELRQEREKLQ 630
Cdd:pfam15921  826 IIQRQEQESVR 836
COG3899 COG3899
Predicted ATPase [General function prediction only];
834-1348 1.26e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 47.16  E-value: 1.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  834 EQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSL 913
Cdd:COG3899    729 ERALELLPPDPEEEYRLALLLELAEALYLAGRFEEAEALLERALAARALAALAALRHGNPPASARAYANLGLLLLGDYEE 808

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  914 FEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEE 993
Cdd:COG3899    809 AYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAA 888

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  994 DLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTA 1073
Cdd:COG3899    889 AAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAA 968

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1074 LSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCL 1153
Cdd:COG3899    969 AAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAA 1048

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1154 REAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESER 1233
Cdd:COG3899   1049 LAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAA 1128

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1234 ISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALG 1313
Cdd:COG3899   1129 ARAAAALLLLAAALALALAALLLLAALLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAA 1208

                          490       500       510
                   ....*....|....*....|....*....|....*
gi 1622834689 1314 ERAEKESRRETLGLRQRLLKGEASLEVMRQELQVA 1348
Cdd:COG3899   1209 LLALALLALEAAALLLLLLLAALALAAALLALRLL 1243
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
620-1075 1.60e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 46.44  E-value: 1.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  620 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVevreALSRATLQRDML 699
Cdd:COG5278     79 EPYEEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALV----RSGEGKALMDEI 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  700 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQE 779
Cdd:COG5278    155 RARLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALEL 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  780 ATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQR 859
Cdd:COG5278    235 LAALALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAA 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  860 QMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLL 939
Cdd:COG5278    315 AAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  940 AKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQ 1019
Cdd:COG5278    395 IAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAAL 474

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622834689 1020 LQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALS 1075
Cdd:COG5278    475 AALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASAEL 530
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 579-831 1.77e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  579 GAMQAQEDAQREvqrlrsanellsreksnlahsLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVR 658
Cdd:COG4942     17 AQADAAAEAEAE---------------------LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  659 RELERSHRQLEQLEGKRSVLAKELVEVREALSR--ATLQRDMLQAEKAEV--AEALTKAEAGRVELELSMTKLRAEEASL 734
Cdd:COG4942     76 QELAALEAELAELEKEIAELRAELEAQKEELAEllRALYRLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  735 QDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQA 814
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235

                          250
                   ....*....|....*..
gi 1622834689  815 QEVLEQQLPTLRHERSR 831
Cdd:COG4942    236 AAAAAERTPAAGFAALK 252
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 855-1031 1.85e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.30  E-value: 1.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  855 RAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEG 934
Cdd:COG1579      3 PEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQL 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  935 QALLLAKE--TLTGELAGLRQQIIAIQEKAsldKELMAQklVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAE 1012
Cdd:COG1579     83 GNVRNNKEyeALQKEIESLKRRISDLEDEI---LELMER--IEELEEELAELEAELAELEAELEEKKAELDEELAELEAE 157

                          170
                   ....*....|....*....
gi 1622834689 1013 RAQLQSQLQREQEELLARL 1031
Cdd:COG1579    158 LEELEAEREELAAKIPPEL 176
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 897-1023 2.35e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 46.23  E-value: 2.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  897 EEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKetltgeLAGLRQQIIAIQEKASldkELMAQklVQA 976
Cdd:COG0542    397 EAAARVRMEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFER------LAELRDELAELEEELE---ALKAR--WEA 465

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1622834689  977 EREAQASLREQRAAHEEDLQRLQrEKEAAWRELEAERAQLQSQLQRE 1023
Cdd:COG0542    466 EKELIEEIQELKEELEQRYGKIP-ELEKELAELEEELAELAPLLREE 511
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1277-1860 2.57e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1277 EARRELQELRRQMKMLdSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGE-ASLEVMRQELQVAQRKLQEQ 1355
Cdd:COG4913    239 RAHEALEDAREQIELL-EPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1356 EGEFRTRERRLLGSLEEARGTEKQQLDHA-RGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLG 1434
Cdd:COG4913    318 LDALREELDELEAQIRGNGGDRLEQLEREiERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1435 GLRSALRRglglgrapspaprpvpgspARDAAaggsgdglsspsnlecspgsqppspgpatspappdldpetvRGALQEF 1514
Cdd:COG4913    398 EELEALEE-------------------ALAEA-----------------------------------------EAALRDL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1515 LQELRSAQRERDDLRTQTSALSHQLAEMEAE-RDHATLRARQLQKA-----VAESEEA-RRSVDGRLSGVQAEMALQEes 1587
Cdd:COG4913    418 RRELRELEAEIASLERRKSNIPARLLALRDAlAEALGLDEAELPFVgelieVRPEEERwRGAIERVLGGFALTLLVPP-- 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1588 vrrsererratlDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASES---RTVKLELQRRSL--- 1661
Cdd:COG4913    496 ------------EHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHpfrAWLEAELGRRFDyvc 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1662 ---EGELQR-----SRLGLSDREAQAQALQDRVDSLQRQV--ADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGL 1731
Cdd:COG4913    564 vdsPEELRRhpraiTRAGQVKGNGTRHEKDDRRRIRSRYVlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDAL 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1732 TEALAQSSASLN---------STQDKNLHLQKALTACE---HDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVA 1799
Cdd:COG4913    644 QERREALQRLAEyswdeidvaSAEREIAELEAELERLDassDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELE 723

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622834689 1800 DLELQQVEAEGQLQQL----REVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAE 1860
Cdd:COG4913    724 QAEEELDELQDRLEAAedlaRLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEE 788
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 560-1310 2.62e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.32  E-value: 2.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  560 ESERRALEEQLQRLRDKTDGAM----QAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEE 635
Cdd:pfam01576  337 EEETRSHEAQLQEMRQKHTQALeeltEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQE 416

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  636 LRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRAtlqRDMLQAEKaevaealtkaea 715
Cdd:pfam01576  417 LQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDT---QELLQEET------------ 481

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  716 gRVELELSmTKLRAEEAslqdslsKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRL 795
Cdd:pfam01576  482 -RQKLNLS-TRLRQLED-------ERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQR 552

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  796 EQEVARQGLEGSLRVA---EQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAarekE 872
Cdd:pfam01576  553 ELEALTQQLEEKAAAYdklEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRA----E 628

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  873 ALAKERAGLAVQLAAAEREGRTLSEEATR----LRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGEL 948
Cdd:pfam01576  629 AEAREKETRALSLARALEEALEAKEELERtnkqLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL 708

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  949 -----AGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWR-ELEAERAQLQSQL-- 1020
Cdd:pfam01576  709 qatedAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKkKLELDLKELEAQIda 788

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1021 ----QREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLkESEKTALSEKLMGTRHSLATISLEMErQK 1096
Cdd:pfam01576  789 ankgREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNL-EAELLQLQEDLAASERARRQAQQERD-EL 866

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1097 RDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRE 1176
Cdd:pfam01576  867 ADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQ 946

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1177 LLEAQRKLRE-SQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEART 1255
Cdd:pfam01576  947 NKELKAKLQEmEGTVKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAE 1026

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622834689 1256 AVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRL 1310
Cdd:pfam01576 1027 KGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSKL 1081
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1511-1850 3.20e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 45.66  E-value: 3.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1511 LQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRR 1590
Cdd:pfam07888   47 LQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAA 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1591 SERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESrtvklelQRRSLEGELQRSRL 1670
Cdd:pfam07888  127 HEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEE-------ELRSLSKEFQELRN 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1671 GLSDREAQAQALQDRVDSL-------QRQVADSEVKAGTLQLTVERLNGALAKVE------ESEGALRDKVRG-LTEALA 1736
Cdd:pfam07888  200 SLAQRDTQVLQLQDTITTLtqklttaHRKEAENEALLEELRSLQERLNASERKVEglgeelSSMAAQRDRTQAeLHQARL 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1737 QSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLE-----------LQQ 1805
Cdd:pfam07888  280 QAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEvelgrekdcnrVQL 359

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1622834689 1806 VEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSL 1850
Cdd:pfam07888  360 SESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETV 404
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 521-709 3.27e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  521 LALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLR----- 595
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKeelae 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  596 ------------SANELLSREKSN--------LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGA 655
Cdd:COG4942    109 llralyrlgrqpPLALLLSPEDFLdavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA 188

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622834689  656 RVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEA 709
Cdd:COG4942    189 ALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 560-1432 3.35e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 45.94  E-value: 3.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  560 ESERRALEEQLQRLRDKtdgamqaQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQ 639
Cdd:pfam01576    4 EEEMQAKEEELQKVKER-------QQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEI 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  640 RDRLEeeqedavqdgARVRRELERShrqlEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVE 719
Cdd:pfam01576   77 LHELE----------SRLEEEEERS----QQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILL 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  720 LELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQeatvareeqerleelrleqev 799
Cdd:pfam01576  143 LEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEK--------------------- 201

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  800 ARQGLEgslrvaeQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQA----------RRAAQRQMEALERAAR 869
Cdd:pfam01576  202 GRQELE-------KAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAAlarleeetaqKNNALKKIRELEAQIS 274

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  870 E-KEALAKERAglavQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQrqlaQLEARREhleaegQALLLAKETLTGEL 948
Cdd:pfam01576  275 ElQEDLESERA----ARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQ----ELRSKRE------QEVTELKKALEEET 340

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  949 AGLRQQIIAIQEKASLDKELMAQKLVQAEReAQASLREQRAAHEEDLQRLQREK---EAAWRELEAERAQLQSQLQ---- 1021
Cdd:pfam01576  341 RSHEAQLQEMRQKHTQALEELTEQLEQAKR-NKANLEKAKQALESENAELQAELrtlQQAKQDSEHKRKKLEGQLQelqa 419

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1022 ------REQEELLARLEAEKEELSEEIATLQQERDEGLLLA-----------------ESEKQQALSLK------ESEKT 1072
Cdd:pfam01576  420 rlseseRQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSkdvsslesqlqdtqellQEETRQKLNLStrlrqlEDERN 499

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1073 ALSEKL---MGTRHSLATISLEMERQKRDAQSRQEQDRSTVNA-------LTSELRDLRAQLEEAVAAhaqeVRRLQEQA 1142
Cdd:pfam01576  500 SLQEQLeeeEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAleegkkrLQRELEALTQQLEEKAAA----YDKLEKTK 575

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1143 QDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEEL 1222
Cdd:pfam01576  576 NRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEEL 655

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1223 RAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRlgre 1302
Cdd:pfam01576  656 ERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFER---- 731

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1303 laELQGRLALGEraekeSRRETLGLRQRLLKGEASLEVMRQELQVAQRK-----LQEQEGEFRTRERRLLGSLEEARGTE 1377
Cdd:pfam01576  732 --DLQARDEQGE-----EKRRQLVKQVRELEAELEDERKQRAQAVAAKKkleldLKELEAQIDAANKGREEAVKQLKKLQ 804

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622834689 1378 KQQLDHARglelKLEATRAEAAELGLRLSAAEGRAQGLEAE-------LARVEAQRRAAEAQ 1432
Cdd:pfam01576  805 AQMKDLQR----ELEEARASRDEILAQSKESEKKLKNLEAEllqlqedLAASERARRQAQQE 862
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 527-779 3.36e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 3.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  527 ALHKRQLQVQDMRGRYEASQdlLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKS 606
Cdd:TIGR02169  773 DLHKLEEALNDLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK 850

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  607 NLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEqedavqdgarvRRELErshRQLEQLEGKRSVLAKELVEVR 686
Cdd:TIGR02169  851 SIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKE-----------RDELE---AQLRELERKIEELEAQIEKKR 916

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  687 EALSRATLQRDMLQAEKAEVaEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALN-------ESLAQDKLDLNRLV 759
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEI-EDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNmlaiqeyEEVLKRLDELKEKR 995

                          250       260
                   ....*....|....*....|
gi 1622834689  760 AQLEEEKAALQGRQRQAEQE 779
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKK 1015
mukB PRK04863
chromosome partition protein MukB;
642-1030 3.62e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 3.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  642 RLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEA-GRVEL 720
Cdd:PRK04863   276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKiERYQA 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  721 ELSMTKLRAEEAS--LQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATvAREEQERLEELRLEQE 798
Cdd:PRK04863   356 DLEELEERLEEQNevVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQ-AVQALERAKQLCGLPD 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  799 VARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQ------EQLAQLSRQLSGreqelEQARRAAQRQMEALERAAREKE 872
Cdd:PRK04863   435 LTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQaahsqfEQAYQLVRKIAG-----EVSRSEAWDVARELLRRLREQR 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  873 ALAKERAGLAVQLAAAEREGRtLSEEATRLRLEKEALEGSLF----EVQRQLAQLEARREHLEAEGQALLLAKETLTGEL 948
Cdd:PRK04863   510 HLAEQLQQLRMRLSELEQRLR-QQQRAERLLAEFCKRLGKNLddedELEQLQEELEARLESLSESVSEARERRMALRQQL 588

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  949 AGLRQQIiaiqekasldKELMAQKLV-QAEREAQASLREQRAAHEEDLQRL------QREKEAAWRELEAERAQLQSQLQ 1021
Cdd:PRK04863   589 EQLQARI----------QRLAARAPAwLAAQDALARLREQSGEEFEDSQDVteymqqLLERERELTVERDELAARKQALD 658


                   ....*....
gi 1622834689 1022 REQEELLAR 1030
Cdd:PRK04863   659 EEIERLSQP 667
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
1043-1476 3.87e-04

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 45.37  E-value: 3.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1043 ATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRA 1122
Cdd:COG5281     15 AAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALAAALAEDAAAAAAA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1123 QLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELR 1202
Cdd:COG5281     95 AEAALAALAAAALALAAAALAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAKAAAAAAAAAALAAAAAAAAAAAAAAA 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1203 RSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARREL 1282
Cdd:COG5281    175 AAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAAALAEQAALAAASAAAQALAALAAAA 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1283 QELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQE--QEGEFR 1360
Cdd:COG5281    255 AAAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAAAAAAQALRAaaQALAAL 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1361 TRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQ----RRAAEAQLGGL 1436
Cdd:COG5281    335 AQRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALAEYADSATNVaaqvAQAATSAFSGL 414

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1622834689 1437 RSALRRGLGLGRAPSPAPRPVPGSPARDAAAGGSGDGLSS 1476
Cdd:COG5281    415 TDALAGAVTTGKLLFDALASSIASIADALANAALASAADA 454
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 544-859 4.02e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 45.60  E-value: 4.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  544 ASQDLLGTLRKQLSDSESERRALEEQlqrlrdktdgaMQAQEDAQRevqrlrsanelLSREKSNLAHSLQVAQQQAEELR 623
Cdd:NF012221  1539 ESSQQADAVSKHAKQDDAAQNALADK-----------ERAEADRQR-----------LEQEKQQQLAAISGSQSQLESTD 1596

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  624 QereklQAAQEELRRQRDRLEEEQEDavqdgarVRRELERSHRQLEQLEGK-----------RSVLAKELVE-VREALSR 691
Cdd:NF012221  1597 Q-----NALETNGQAQRDAILEESRA-------VTKELTTLAQGLDALDSQatyagesgdqwRNPFAGGLLDrVQEQLDD 1664

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  692 ATLQ--------RDMLQAEKAEVAEALTKAEAGRVELElsmtKLRAEeasLQDSLSKLSALNESLAQDKLDlNRLVAQLE 763
Cdd:NF012221  1665 AKKIsgkqladaKQRHVDNQQKVKDAVAKSEAGVAQGE----QNQAN---AEQDIDDAKADAEKRKDDALA-KQNEAQQA 1736

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  764 EEKA--ALQGRQRQAEQEATVAREEQERLEELRLEQEVA------RQGLEGSlRVAEQAQEVlEQQLPTLRHERSRLQEQ 835
Cdd:NF012221  1737 ESDAnaAANDAQSRGEQDASAAENKANQAQADAKGAKQDesdkpnRQGAAGS-GLSGKAYSV-EGVAEPGSHINPDSPAA 1814

                          330       340
                   ....*....|....*....|....*.
gi 1622834689  836 L-AQLSRQLSGREQE-LEQARRAAQR 859
Cdd:NF012221  1815 AdGRFSEGLTEQEQEaLEGATNAVNR 1840
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 861-1382 4.18e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.60  E-value: 4.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  861 MEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEatrLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQallla 940
Cdd:pfam12128  268 KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDE---LNGELSAADAAVAKDRSELEALEDQHGAFLDADI----- 339

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  941 kETLTGELAGLRQQIIAIQE-KASLDKELMAQKLVQAEREAQASLREQRAAHE-EDL-QRLQREKEAAWRELEAERAQLQ 1017
Cdd:pfam12128  340 -ETAAADQEQLPSWQSELENlEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDiAGIkDKLAKIREARDRQLAVAEDDLQ 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1018 SQLQREQEELLARLEAEkeelseeiatlqQERDEGLLLAESEkqqaLSLKESEKTALSEKLMGTRHSLATISlemerqkr 1097
Cdd:pfam12128  419 ALESELREQLEAGKLEF------------NEEEYRLKSRLGE----LKLRLNQATATPELLLQLENFDERIE-------- 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1098 DAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREA----EELRTQLRLLEDARDGL 1173
Cdd:pfam12128  475 RAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAgtllHFLRKEAPDWEQSIGKV 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1174 -RRELLEAQRKLRESQEGREVQRQEAGELRRSLgeGAKEREALRRSNEELRAAVKKAESerislklANEDKEQKLALLEE 1252
Cdd:pfam12128  555 iSPELLHRTDLDPEVWDGSVGGELNLYGVKLDL--KRIDVPEWAASEEELRERLDKAEE-------ALQSAREKQAAAEE 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1253 ARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKmldSENTRLGRELAELQgRLALGERAEKESRRETLGLRQRLL 1332
Cdd:pfam12128  626 QLVQANGELEKASREETFARTALKNARLDLRRLFDEKQ---SEKDKKNKALAERK-DSANERLNSLEAQLKQLDKKHQAW 701

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1333 KgEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 1382
Cdd:pfam12128  702 L-EEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELK 750
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 583-1300 4.37e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.34  E-value: 4.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  583 AQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQedavqdgaRVRRELE 662
Cdd:TIGR00618  192 LHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL--------KKQQLLK 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  663 RSHRQLEQLEGkrsvLAKELVEVREALSRATlQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLraeeaslqdslSKLS 742
Cdd:TIGR00618  264 QLRARIEELRA----QEAVLEETQERINRAR-KAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSR-----------AKLL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  743 ALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEelrleqevarqgLEGSLRVAEQAQEVLEQQL 822
Cdd:TIGR00618  328 MKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHT------------LTQHIHTLQQQKTTLTQKL 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  823 PTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRL 902
Cdd:TIGR00618  396 QSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQL 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  903 R---------LEKEALEGS-LFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELmaqk 972
Cdd:TIGR00618  476 QtkeqihlqeTRKKAVVLArLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQL---- 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  973 lvQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEG 1052
Cdd:TIGR00618  552 --TSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1053 LLLAESEKQQALSLKESEKTALSEKLMGTR---HSLATISLEMER-QKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAV 1128
Cdd:TIGR00618  630 VRLHLQQCSQELALKLTALHALQLTLTQERvreHALSIRVLPKELlASRQLALQKMQSEKEQLTYWKEMLAQCQTLLREL 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1129 AAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQ-LRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGE 1207
Cdd:TIGR00618  710 ETHIEEYDREFNEIENASSSLGSDLAAREDALNQsLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQF 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1208 GAKEREALRRSNEELRAAVK-KAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVErsrlEARRELQELR 1286
Cdd:TIGR00618  790 FNRLREEDTHLLKTLEAEIGqEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYE----ECSKQLAQLT 865

                          730
                   ....*....|....
gi 1622834689 1287 RQMKMLDSENTRLG 1300
Cdd:TIGR00618  866 QEQAKIIQLSDKLN 879
PTZ00121 PTZ00121
MAEBL; Provisional
 88-766 4.45e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 4.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   88 QELSRVEDLLAQSRAERDELAiKYNAVSERLEQTLRLE-SGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQ 166
Cdd:PTZ00121  1131 EEARKAEDARKAEEARKAEDA-KRVEIARKAEDARKAEeARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAE 1209

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  167 Q-RQAQLVQRLQ-GKILQYKKRCSELEQQLLERSgelEQQRLRNTEHSQDLESAliRLEEEQQRSASLAQVNAMLREQLD 244
Cdd:PTZ00121  1210 EeRKAEEARKAEdAKKAEAVKKAEEAKKDAEEAK---KAEEERNNEEIRKFEEA--RMAHFARRQAAIKAEEARKADELK 1284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  245 QAglanqalsEDIRKvtSDWARSRKELEQREAAWRREEESfnayfsnehsrllllwRQVVGFRRLVSEVKMFTErDLLQL 324
Cdd:PTZ00121  1285 KA--------EEKKK--ADEAKKAEEKKKADEAKKKAEEA----------------KKADEAKKKAEEAKKKAD-AAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  325 GGELARTSRAVQEAGLGLSTGLRLAESRTEAALEKQALLQAQLEE-QLRDKVLREKDLAQQQMQSDLDKADLSARVTELG 403
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAaKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  404 LAVERLQKQNLEK---DQVNKDLTEKLEALESLRLQEQA---------ALETEDGEGLQQTLRDLAQAVLSDSESGVQLS 471
Cdd:PTZ00121  1418 KKADEAKKKAEEKkkaDEAKKKAEEAKKADEAKKKAEEAkkaeeakkkAEEAKKADEAKKKAEEAKKADEAKKKAEEAKK 1497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  472 GSERTADASDGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLA--LIHSALHKRQLQVQDMRGRYEASQDLL 549
Cdd:PTZ00121  1498 KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAdeLKKAEELKKAEEKKKAEEAKKAEEDKN 1577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  550 GTLRKQLSDSESERRALEEQLQRLRD-KTDGAMQAQ--EDAQREVQRLRSANELlSREKSNLAHSLQVAQQQAEELRQER 626
Cdd:PTZ00121  1578 MALRKAEEAKKAEEARIEEVMKLYEEeKKMKAEEAKkaEEAKIKAEELKKAEEE-KKKVEQLKKKEAEEKKKAEELKKAE 1656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  627 EKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREA--LSRATLQRDMLQAE-K 703
Cdd:PTZ00121  1657 EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAeeLKKAEEENKIKAEEaK 1736

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622834689  704 AEVAEALTKAEAGRVElELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 766
Cdd:PTZ00121  1737 KEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 566-928 4.50e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 45.27  E-value: 4.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  566 LEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEE 645
Cdd:pfam07888   36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  646 EQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMT 725
Cdd:pfam07888  116 EKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  726 KLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLE 805
Cdd:pfam07888  196 ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELH 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  806 GSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEA----LAKERAGL 881
Cdd:pfam07888  276 QARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKleveLGREKDCN 355

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1622834689  882 AVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 928
Cdd:pfam07888  356 RVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
mukB PRK04863
chromosome partition protein MukB;
886-1355 4.62e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.33  E-value: 4.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  886 AAAEREGRTLSEEATRLRLEK-------EALEGSLFEVQRQLAQLEARREHLEAEGQAlllAKETLTGELAGLRQQIIAI 958
Cdd:PRK04863   275 MRHANERRVHLEEALELRRELytsrrqlAAEQYRLVEMARELAELNEAESDLEQDYQA---ASDHLNLVQTALRQQEKIE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  959 QEKASLDkelmaqklvqaerEAQASLREQRAAHEEdLQRLQREKEAAWRELEAERAQLQSQLQREQEELlarleaekeel 1038
Cdd:PRK04863   352 RYQADLE-------------ELEERLEEQNEVVEE-ADEQQEENEARAEAAEEEVDELKSQLADYQQAL----------- 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1039 seeiaTLQQERdeglllaESEKQQALSLKESEKTALSeklmgtrhsLATISLEmerqkrDAQSRQEQDRSTVNALTSELR 1118
Cdd:PRK04863   407 -----DVQQTR-------AIQYQQAVQALERAKQLCG---------LPDLTAD------NAEDWLEEFQAKEQEATEELL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1119 DLRAQLEEAVAAHAQevrrLQEQAQDLGKQRDSCLREAEElrtqlrllEDARDGLRRelLEAQRKLRESQEGRevqRQEA 1198
Cdd:PRK04863   460 SLEQKLSVAQAAHSQ----FEQAYQLVRKIAGEVSRSEAW--------DVARELLRR--LREQRHLAEQLQQL---RMRL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1199 GELRRSLgegakereALRRSNEELRAAVKKaeseRISLKLANEDKEQKLAlleeartavgKEAGELRTGLQEVERSRLEA 1278
Cdd:PRK04863   523 SELEQRL--------RQQQRAERLLAEFCK----RLGKNLDDEDELEQLQ----------EELEARLESLSESVSEARER 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1279 RRELQELRRQMKMLDSENTRLGRELAELQGRLA-LGER--AEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQ 1355
Cdd:PRK04863   581 RMALRQQLEQLQARIQRLAARAPAWLAAQDALArLREQsgEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEE 660
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 826-1299 4.76e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 45.12  E-value: 4.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  826 RHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAERE-GRTLSEEATRLRL 904
Cdd:pfam05557    1 RAELIESKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEaEEALREQAELNRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  905 EKEALEGSLFEVQRQLAQLEARREhleaegqalllAKETLTGELAGLRQQI-IAIQEKASLDKELMAQKLVQAEREAQAS 983
Cdd:pfam05557   81 KKKYLEALNKKLNEKESQLADARE-----------VISCLKNELSELRRQIqRAELELQSTNSELEELQERLDLLKAKAS 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  984 LREQRAAHEEDLQRLQREKEAAWRELEAERAQ----------LQSQLQR--EQEELLARLEAEKEELSEEIAT--LQQER 1049
Cdd:pfam05557  150 EAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSqeqdseivknSKSELARipELEKELERLREHNKHLNENIENklLLKEE 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1050 DEGL---LLAESEKQQALSLKESEKTALSEKL-----MGTRHSLATISLEMERQKRDA-QSRQEQDRSTVNALTSELRDL 1120
Cdd:pfam05557  230 VEDLkrkLEREEKYREEAATLELEKEKLEQELqswvkLAQDTGLNLRSPEDLSRRIEQlQQREIVLKEENSSLTSSARQL 309

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1121 RAQLEEAVaahaQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREvqrqeage 1200
Cdd:pfam05557  310 EKARRELE----QELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSNYSPQ-------- 377

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1201 LRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEeaRTAVGKEAGELRTGLQEVERSRLEARR 1280
Cdd:pfam05557  378 LLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALR--QQESLADPSYSKEEVDSLRRKLETLEL 455

                          490
                   ....*....|....*....
gi 1622834689 1281 ELQELRRQMKMLDSENTRL 1299
Cdd:pfam05557  456 ERQRLREQKNELEMELERR 474
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1599-2008 4.83e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.33  E-value: 4.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1599 LDQIATLERSLQATESELRASQEKISKMKANETKLEGdkrrlkevldasesrtvklelQRRSLEGELQRSRLGLSdREAQ 1678
Cdd:COG3096    284 SERALELRRELFGARRQLAEEQYRLVEMARELEELSA---------------------RESDLEQDYQAASDHLN-LVQT 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1679 AQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTA 1758
Cdd:COG3096    342 ALRQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQA 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1759 CEHDRQVLQE---RLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQrQEGEAAALHMVQK 1835
Cdd:COG3096    422 LEKARALCGLpdlTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGE-VERSQAWQTAREL 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1836 LQDER--RLLQERLGSLQRALAQLE---AEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTL 1910
Cdd:COG3096    501 LRRYRsqQALAQRLQQLRAQLAELEqrlRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQR 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1911 TGAELELAEAQRQIQQLEAQvvvleqshSPAQLEV-DAQQQQHLELQQEVERLRSAQVQTERTLEaRERAHRQrvrgLEE 1989
Cdd:COG3096    581 SELRQQLEQLRARIKELAAR--------APAWLAAqDALERLREQSGEALADSQEVTAAMQQLLE-REREATV----ERD 647

                          410
                   ....*....|....*....
gi 1622834689 1990 QVSTLKGQLQQELRRSSAP 2008
Cdd:COG3096    648 ELAARKQALESQIERLSQP 666
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
982-1468 5.17e-04

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 44.99  E-value: 5.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  982 ASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQ 1061
Cdd:COG5281      1 AAALAAAAALAAAAAAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADAL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1062 QALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQ 1141
Cdd:COG5281     81 AAALAEDAAAAAAAAEAALAALAAAALALAAAALAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAKAAAAAAAAAALA 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1142 AQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEE 1221
Cdd:COG5281    161 AAAAAAAAAAAAAAAAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAAALAEQAALAAA 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1222 LRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGR 1301
Cdd:COG5281    241 SAAAQALAALAAAAAAAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAAAAA 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1302 ELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEE----ARGTE 1377
Cdd:COG5281    321 AQALRAAAQALAALAQRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALAEyadsATNVA 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1378 KQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPV 1457
Cdd:COG5281    401 AQVAQAATSAFSGLTDALAGAVTTGKLLFDALASSIASIADALANAALASAADALGGALAGALGGLFGGGGGAAAGAAVY 480

                          490
                   ....*....|.
gi 1622834689 1458 PGSPARDAAAG 1468
Cdd:COG5281    481 AGALGPFASGG 491
mukB PRK04863
chromosome partition protein MukB;
1543-1936 5.29e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.33  E-value: 5.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1543 EAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMalqeesvrrsererratldqiATLERSLQATESELRASQEK 1622
Cdd:PRK04863   278 ANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMAREL---------------------AELNEAESDLEQDYQAASDH 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1623 ISKMKANETKLEGDKRRLKEVLDASEsrtvKLELQRRSLEGelqrSRLGLSDREAQAQALQDRVDSLQRQVAD------- 1695
Cdd:PRK04863   337 LNLVQTALRQQEKIERYQADLEELEE----RLEEQNEVVEE----ADEQQEENEARAEAAEEEVDELKSQLADyqqaldv 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1696 SEVKAGTLQLTVERLNGA----------LAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALT-----ACE 1760
Cdd:PRK04863   409 QQTRAIQYQQAVQALERAkqlcglpdltADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQlvrkiAGE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1761 HDRQVLQerlDAARQALSEARKQsSSLGEQVQTLRGEVADLElQQVEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDER 1840
Cdd:PRK04863   489 VSRSEAW---DVARELLRRLREQ-RHLAEQLQQLRMRLSELE-QRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEEL 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1841 RLLQERLGSLQRALAQ----LEAEKREVERSALRLEKDRVALRRTLDKVERekLRSH-----EDTVRLSAEKGRLDRTLT 1911
Cdd:PRK04863   564 EARLESLSESVSEARErrmaLRQQLEQLQARIQRLAARAPAWLAAQDALAR--LREQsgeefEDSQDVTEYMQQLLERER 641

                          410       420
                   ....*....|....*....|....*
gi 1622834689 1912 GAELELAEAQRQIQQLEAQVVVLEQ 1936
Cdd:PRK04863   642 ELTVERDELAARKQALDEEIERLSQ 666
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1522-1939 5.32e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.11  E-value: 5.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1522 QRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQ 1601
Cdd:pfam15921  418 RRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT 497

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1602 IATLERSLQATESELRASQEKISKMKA---------NETKLEGDKRRLKEvldaSESRTVKLELQRRSLEGELQRSRLG- 1671
Cdd:pfam15921  498 VSDLTASLQEKERAIEATNAEITKLRSrvdlklqelQHLKNEGDHLRNVQ----TECEALKLQMAEKDKVIEILRQQIEn 573

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1672 ----LSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQD 1747
Cdd:pfam15921  574 mtqlVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQ 653

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1748 KNLHLQKALTACEHDRQVLQERLDAARQALseaRKQSsslgEQVQTLRGEvadLELQQVEAEGQLQQLREVLRQRQEGEA 1827
Cdd:pfam15921  654 ERDQLLNEVKTSRNELNSLSEDYEVLKRNF---RNKS----EEMETTTNK---LKMQLKSAQSELEQTRNTLKSMEGSDG 723

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1828 AALHMVQKLQDERR-------LLQERLGSLQRALAQLEAEKR--EVERSALRLEKDRVALRRTLDKVEREKLRSHEDtvR 1898
Cdd:pfam15921  724 HAMKVAMGMQKQITakrgqidALQSKIQFLEEAMTNANKEKHflKEEKNKLSQELSTVATEKNKMAGELEVLRSQER--R 801

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1622834689 1899 LSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHS 1939
Cdd:pfam15921  802 LKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHT 842
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 560-878 5.92e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.89  E-value: 5.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  560 ESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQ 639
Cdd:pfam07888   72 ERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETE 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  640 RDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVE 719
Cdd:pfam07888  152 LERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAE 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  720 LELSMTKLRAEEASLQDSLSKLSALNEslaqdklDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEV 799
Cdd:pfam07888  232 NEALLEELRSLQERLNASERKVEGLGE-------ELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQ 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  800 ARQGLEGSL-----RVAEQAQEVLEQQlPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEAL 874
Cdd:pfam07888  305 ERETLQQSAeadkdRIEKLSAELQRLE-ERLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQL 383


                   ....
gi 1622834689  875 AKER 878
Cdd:pfam07888  384 QAEK 387
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1597-1991 6.19e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 6.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1597 ATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDRE 1676
Cdd:PRK02224   234 ETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1677 AQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKAL 1756
Cdd:PRK02224   314 ARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEI 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1757 TACEH-------DRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVAdlELQQVEAEGQLQQLREVLRQRQEGEAAA 1829
Cdd:PRK02224   394 EELRErfgdapvDLGNAEDFLEELREERDELREREAELEATLRTARERVE--EAEALLEAGKCPECGQPVEGSPHVETIE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1830 --LHMVQKLQDERRLLQERLGSLQRALAQLEAEKrEVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLD 1907
Cdd:PRK02224   472 edRERVEELEAELEDLEEEVEEVEERLERAEDLV-EAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELE 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1908 RTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDA------QQQQHLELQQEVERLRSAQVQ-TERTLEARER-- 1978
Cdd:PRK02224   551 AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESlerirtLLAAIADAEDEIERLREKREAlAELNDERRERla 630

                          410
                   ....*....|...
gi 1622834689 1979 AHRQRVRGLEEQV 1991
Cdd:PRK02224   631 EKRERKRELEAEF 643
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 882-1108 6.53e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 6.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  882 AVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEK 961
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  962 ASLDKELMAQKLVQAEREAQASlREQRAAHEEDLQRLQReKEAAWRELEAERAQLQSQLQREQEEL---LARLEAEKEEL 1038
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQP-PLALLLSPEDFLDAVR-RLQYLKYLAPARREQAEELRADLAELaalRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1039 SEEIATLQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRS 1108
Cdd:COG4942    177 EALLAELEEERAA-LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
805-1251 6.93e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 44.51  E-value: 6.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  805 EGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAK--ERAGLA 882
Cdd:COG5278     82 EEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEirARLLLL 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  883 VQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKA 962
Cdd:COG5278    162 ALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALA 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  963 SLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEI 1042
Cdd:COG5278    242 LALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAA 321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1043 ATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRA 1122
Cdd:COG5278    322 AAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAA 401

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1123 QLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELR 1202
Cdd:COG5278    402 AAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAA 481

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 1622834689 1203 RSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLE 1251
Cdd:COG5278    482 AALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASAEL 530
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
971-1437 7.99e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.67  E-value: 7.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  971 QKLVQAEREAQASLREQRAAHEEDLQRLqREKEAAWRELEAERAQLQSQLQR--EQEELLARLEAEKEELSEEIATLQ-- 1046
Cdd:PRK03918   182 EKFIKRTENIEELIKEKEKELEEVLREI-NEISSELPELREELEKLEKEVKEleELKEEIEELEKELESLEGSKRKLEek 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1047 ----QERDEGLLLAESE-KQQALSLKESEKTA-----LSEKLMGTRHSLATISLEMERQKRDAQSRQEQ------DRSTV 1110
Cdd:PRK03918   261 irelEERIEELKKEIEElEEKVKELKELKEKAeeyikLSEFYEEYLDELREIEKRLSRLEEEINGIEERikeleeKEERL 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1111 NALTSELRDLRAQLEEAVAAHA--QEVRRLQEQAQDLGKQRDSclREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQ 1188
Cdd:PRK03918   341 EELKKKLKELEKRLEELEERHElyEEAKAKKEELERLKKRLTG--LTPEKLEKELEELEKAKEEIEEEISKITARIGELK 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1189 EGREVQRQEAGELR----------RSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVG 1258
Cdd:PRK03918   419 KEIKELKKAIEELKkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1259 KEAGE----LRTGLQEVERSRLEAR-RELQELRRQMKMLDSENTRLGREL---AELQGRLALGERAEKESRRETLGLRQR 1330
Cdd:PRK03918   499 KELAEqlkeLEEKLKKYNLEELEKKaEEYEKLKEKLIKLKGEIKSLKKELeklEELKKKLAELEKKLDELEEELAELLKE 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1331 LL----KGEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLS 1406
Cdd:PRK03918   579 LEelgfESVEELEERLKELEPFYNEYLELKDA-EKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS 657

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 1622834689 1407 AAEGRA------------QGLEAELARVEAQRRAAEAQLGGLR 1437
Cdd:PRK03918   658 EEEYEElreeylelsrelAGLRAELEELEKRREEIKKTLEKLK 700
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1116-1449 8.14e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.12  E-value: 8.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1116 ELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQR 1195
Cdd:COG4372     14 SLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1196 QEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSR 1275
Cdd:COG4372     94 AELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1276 LEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQ 1355
Cdd:COG4372    174 QALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLE 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1356 EGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGG 1435
Cdd:COG4372    254 EVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALA 333

                          330
                   ....*....|....
gi 1622834689 1436 LRSALRRGLGLGRA 1449
Cdd:COG4372    334 ILLAELADLLQLLL 347
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 816-1290 8.21e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 8.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  816 EVLEQQLPTLRHERSRLQEQLAQLSRQLSGRE------QELEQARRAAQRQMEALERA----AREKEALAKERAGLAVQL 885
Cdd:TIGR04523  169 EELENELNLLEKEKLNIQKNIDKIKNKLLKLElllsnlKKKIQKNKSLESQISELKKQnnqlKDNIEKKQQEINEKTTEI 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  886 AAAEREGRTLSEEATRLR-------LEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKetLTGELAGLRQQIIAI 958
Cdd:TIGR04523  249 SNTQTQLNQLKDEQNKIKkqlsekqKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKE--LKSELKNQEKKLEEI 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  959 QEKASLDKELMAQ---KLVQAEREAQ------ASLREQRAAHEEDLQRLQREKEAAWRE---LEAERAQLQSQLQrEQEE 1026
Cdd:TIGR04523  327 QNQISQNNKIISQlneQISQLKKELTnsesenSEKQRELEEKQNEIEKLKKENQSYKQEiknLESQINDLESKIQ-NQEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1027 LLARLEAEKEELSEEIATLQQERDEglLLAESEKQQA----LSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSR 1102
Cdd:TIGR04523  406 LNQQKDEQIKKLQQEKELLEKEIER--LKETIIKNNSeikdLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1103 QEQDRSTVNALTSELRDLRaqleeavaahaQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQR 1182
Cdd:TIGR04523  484 LEQKQKELKSKEKELKKLN-----------EEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1183 KLRESQEGREVQrqeagELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAG 1262
Cdd:TIGR04523  553 ELKKENLEKEID-----EKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENE 627

                          490       500
                   ....*....|....*....|....*...
gi 1622834689 1263 ELRTGLQEVERSRLEARRELQELRRQMK 1290
Cdd:TIGR04523  628 KLSSIIKNIKSKKNKLKQEVKQIKETIK 655
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 569-1432 8.39e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.65  E-value: 8.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  569 QLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEE--- 645
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEieh 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  646 ------EQEDAVQDGARVRRELERSHRQLEQLEGK----RSVLAKELVEVREALSRA---TLQRDMLQAEKAEVAEALTK 712
Cdd:TIGR00606  260 nlskimKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQLNDLYHNHQRTVREkerELVDCQRELEKLNKERRLLN 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  713 AEAGRVELELSMTKLRAEEASLQdSLSKLSALNESLAQDKLDLNRLVAQLEEE-----KAALQGRQRQAEQEATVAREEQ 787
Cdd:TIGR00606  340 QEKTELLVEQGRLQLQADRHQEH-IRARDSLIQSLATRLELDGFERGPFSERQiknfhTLVIERQEDEAKTAAQLCADLQ 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  788 ERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLsgreqELEQARRAAQRQMEALERA 867
Cdd:TIGR00606  419 SKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIL-----ELDQELRKAERELSKAEKN 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  868 ArEKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLA------K 941
Cdd:TIGR00606  494 S-LTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpnK 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  942 ETLTGELAGLRQQIIAIQEK-ASLDKELMAQKLVQAE-REAQASLREQRAAHEE-------------DLQRLQREKEAAW 1006
Cdd:TIGR00606  573 KQLEDWLHSKSKEINQTRDRlAKLNKELASLEQNKNHiNNELESKEEQLSSYEDklfdvcgsqdeesDLERLKEEIEKSS 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1007 RELEAERA-----------------------QLQSQLQREQEELLARLEA-------EKEELSEEIATLQQERDEGLLLA 1056
Cdd:TIGR00606  653 KQRAMLAGatavysqfitqltdenqsccpvcQRVFQTEAELQEFISDLQSklrlapdKLKSTESELKKKEKRRDEMLGLA 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1057 ESeKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALT--SELRDLRAQLEEAVAAHAQE 1134
Cdd:TIGR00606  733 PG-RQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTdvTIMERFQMELKDVERKIAQQ 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1135 VRRLqeQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEgrevQRQEAGELRRSLGEGAKEREA 1214
Cdd:TIGR00606  812 AAKL--QGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKS----KTNELKSEKLQIGTNLQRRQQ 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1215 LRRSNEELRAAVKkaeseriSLKLANEDKEQKLALLEEARTAVGKEAGELrtgLQEVERSRLEARRELQELRRQMKMLDS 1294
Cdd:TIGR00606  886 FEEQLVELSTEVQ-------SLIREIKDAKEQDSPLETFLEKDQQEKEEL---ISSKETSNKKAQDKVNDIKEKVKNIHG 955

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1295 ENTRLGRELAELQGRLALGERAEKESRRETLG-LRQRLLKGEASLEVMRQELQVA-QRKLQEQEGEFRTRERRLLGSLEE 1372
Cdd:TIGR00606  956 YMKDIENKIQDGKDDYLKQKETELNTVNAQLEeCEKHQEKINEDMRLMRQDIDTQkIQERWLQDNLTLRKRENELKEVEE 1035

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622834689 1373 ARGTEKQQLDHARGLELKLEATRAEAA--ELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQ 1432
Cdd:TIGR00606 1036 ELKQHLKEMGQMQVLQMKQEHQKLEENidLIKRNHVLALGRQKGYEKEIKHFKKELREPQFR 1097
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 959-1176 9.00e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 9.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  959 QEKASLDKELMA-QKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQsQLQREQEELLARLEAEKEE 1037
Cdd:COG4942     27 AELEQLQQEIAElEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-ELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1038 LSEEIATLQQ--ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDaqsrQEQDRSTVNALTS 1115
Cdd:COG4942    106 LAELLRALYRlgRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE----LEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622834689 1116 ELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRE 1176
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 527-873 9.90e-04

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 43.90  E-value: 9.90e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  527 ALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKS 606
Cdd:pfam19220    7 LLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  607 NLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 686
Cdd:pfam19220   87 ELVARLAKLEAALREAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATAR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  687 EALSRATLQRDMLQAEKAEVAEALTKAEAgrvelelsmtKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 766
Cdd:pfam19220  167 ERLALLEQENRRLQALSEEQAAELAELTR----------RLAELETQLDATRARLRALEGQLAAEQAERERAEAQLEEAV 236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  767 AALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLsgr 846
Cdd:pfam19220  237 EAHRAERASLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQF--- 313

                          330       340
                   ....*....|....*....|....*..
gi 1622834689  847 eQELEQARRAAQRQMEALERAAREKEA 873
Cdd:pfam19220  314 -QEMQRARAELEERAEMLTKALAAKDA 339
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 551-1070 1.10e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.24  E-value: 1.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  551 TLRKQLSDSESERRALEEQLQRLR---DKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQERE 627
Cdd:TIGR04523  163 DLKKQKEELENELNLLEKEKLNIQkniDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEIN 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  628 KLQAAQEELRRQRDRLEEEQEdavqdgaRVRRELERSHRQLEQLEGKRSVLAKELVEVREALSraTLQRDMLQAEKAEVA 707
Cdd:TIGR04523  243 EKTTEISNTQTQLNQLKDEQN-------KIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIS--DLNNQKEQDWNKELK 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  708 EALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRlvaQLEEEKAALQGRQRQAE---QEATVAR 784
Cdd:TIGR04523  314 SELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQR---ELEEKQNEIEKLKKENQsykQEIKNLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  785 EEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGRE---QELEQARRAAQRQM 861
Cdd:TIGR04523  391 SQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKEliiKNLDNTRESLETQL 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  862 EALERAAREKEAlakeraglavQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEgqalllaK 941
Cdd:TIGR04523  471 KVLSRSINKIKQ----------NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESE-------K 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  942 ETLTGELAGLRQQIIAIQE---KASLDKELMA--QKLVQAEREAQASLREQRAAhEEDLQRLQREKEAAWRELEaERAQL 1016
Cdd:TIGR04523  534 KEKESKISDLEDELNKDDFelkKENLEKEIDEknKEIEELKQTQKSLKKKQEEK-QELIDQKEKEKKDLIKEIE-EKEKK 611

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622834689 1017 QSQLQREQEELlarlEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESE 1070
Cdd:TIGR04523  612 ISSLEKELEKA----KKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKW 661
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1772-1945 1.17e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.08  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1772 AARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVL---RQRQEGEAAALHMVQKLQDERRLLQERLG 1848
Cdd:COG2433    403 HEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELseaRSEERREIRKDREISRLDREIERLERELE 482

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1849 SLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEaqrQIQQLE 1928
Cdd:COG2433    483 EERERIEELKRKLERLKELWKLEHSGELVPVKVVEKFTKEAIRRLEEEYGLKEGDVVYLRDASGAGRSTAE---LLAEAG 559

                          170
                   ....*....|....*..
gi 1622834689 1929 AQVVVLEQSHSPAQLEV 1945
Cdd:COG2433    560 PRAVIVPGELSEAADEV 576
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1078-1360 1.28e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1078 LMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLE---EAVAAHAQEVRRLQEQAQDLGKQRDSCLR 1154
Cdd:COG4372     15 LFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEqleEELEQARSELEQLEEELEELNEQLQAAQA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1155 EAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERI 1234
Cdd:COG4372     95 ELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQ 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1235 SLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGE 1314
Cdd:COG4372    175 ALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEE 254

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1622834689 1315 RAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFR 1360
Cdd:COG4372    255 VILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLAL 300
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 580-743 1.29e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  580 AMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVR- 658
Cdd:COG1579      1 AMPEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEe 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  659 --------RELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAgrvELELSMTKLRAE 730
Cdd:COG1579     81 qlgnvrnnKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKA---ELDEELAELEAE 157

                          170
                   ....*....|...
gi 1622834689  731 EASLQDSLSKLSA 743
Cdd:COG1579    158 LEELEAEREELAA 170
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 819-1229 1.37e-03

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 43.90  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  819 EQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQArrAAQRQMEALERAAREK-EALAKERAGLAVQLAAAEREGRTL-- 895
Cdd:pfam13166   95 QEKIAKLKKEIKDHEEKLDAAEANLQKLDKEKEKL--EADFLDECWKKIKRKKnSALSEALNGFKYEANFKSRLLREIek 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  896 --SEEATRLRLEK-EALEGSLFEVQRQ-LAQLEAR-REHLEAEGQALLLAKETLTGelaglrqqiIAIQEkasLDKELMA 970
Cdd:pfam13166  173 dnFNAGVLLSDEDrKAALATVFSDNKPeIAPLTFNvIDFDALEKAEILIQKVIGKS---------SAIEE---LIKNPDL 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  971 QKLVQAEREAqaslreqraaHEEDL-------QRLQREKeaaWRELEA----ERAQLQSQLQREQEELLaRLEAEKEELS 1039
Cdd:pfam13166  241 ADWVEQGLEL----------HKAHLdtcpfcgQPLPAER---KAALEAhfddEFTEFQNRLQKLIEKVE-SAISSLLAQL 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1040 EEIATLQQERDEglllAESEKQQALSLKEsektALSEKLMGTRHslatislEMERQKRDAQSRQEQDRSTvnALTSELRD 1119
Cdd:pfam13166  307 PAVSDLASLLSA----FELDVEDIESEAE----VLNSQLDGLRR-------ALEAKRKDPFKSIELDSVD--AKIESIND 369

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1120 LRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDscLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAG 1199
Cdd:pfam13166  370 LVASINELIAKHNEITDNFEEEKNKAKKKLR--LHLVEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKLREEIK 447

                          410       420       430
                   ....*....|....*....|....*....|....*..
gi 1622834689 1200 ELRRSLG-------EGAKEREALRRSNEELRAAVKKA 1229
Cdd:pfam13166  448 ELEAQLRdhkpgadEINKLLKAFGFGELELSFNEEGK 484
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1018-1346 1.49e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.95  E-value: 1.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1018 SQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQ----QALSLKESEKTALSEKLMGTRHSLATISLEME 1093
Cdd:pfam15921  223 SKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQdrieQLISEHEVEITGLTEKASSARSQANSIQSQLE 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1094 RQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGL 1173
Cdd:pfam15921  303 IIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKL 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1174 RRELLEAQRKLR-ESQEGREVQRQEAG------ELRRSLGEGAKEREALRRSNEELRAAVK-KAESERISLKLANEDKEQ 1245
Cdd:pfam15921  383 LADLHKREKELSlEKEQNKRLWDRDTGnsitidHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEK 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1246 KLAL---LEEARTAVGKEAGEL---RTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGR----ELAELQGRLALGER 1315
Cdd:pfam15921  463 VSSLtaqLESTKEMLRKVVEELtakKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSrvdlKLQELQHLKNEGDH 542

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1622834689 1316 AeKESRRETLGLRQRLLKGEASLEVMRQELQ 1346
Cdd:pfam15921  543 L-RNVQTECEALKLQMAEKDKVIEILRQQIE 572
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 884-1220 1.62e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.57  E-value: 1.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  884 QLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEgqalllaketlTGELAGLRQQ--IIAIQEK 961
Cdd:pfam17380  273 QLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAE-----------KARQAEMDRQaaIYAEQER 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  962 ASLDKELMAQKLVQAEREAQ-ASLREQRAAHE----EDLQRLQREK----EAAWRELEAERAqlqsqlQREQEELLARLE 1032
Cdd:pfam17380  342 MAMERERELERIRQEERKRElERIRQEEIAMEisrmRELERLQMERqqknERVRQELEAARK------VKILEEERQRKI 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1033 AEKEELSEEIATLQQE-RDEGLLLAESEKQQALS---LKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRS 1108
Cdd:pfam17380  416 QQQKVEMEQIRAEQEEaRQREVRRLEEERAREMErvrLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRK 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1109 TVNALTSELRdlRAQLEEavaahaQEVRRLQEQAQDlgkQRDSCLREAEElrtqlrlledardglRRELLEAQRKLRESQ 1188
Cdd:pfam17380  496 ILEKELEERK--QAMIEE------ERKRKLLEKEME---ERQKAIYEEER---------------RREAEEERRKQQEME 549

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1622834689 1189 EGREVQRQ--EAGELRRSLGEGAKEREALRRSNE 1220
Cdd:pfam17380  550 ERRRIQEQmrKATEERSRLEAMEREREMMRQIVE 583
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1267-1997 1.80e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 1.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1267 GLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQG-----------RLALGERAEKESRRETLGLRQRLLKGE 1335
Cdd:TIGR02169  164 GVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRerekaeryqalLKEKREYEGYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1336 ASLEVMRQELQVAQRKLQEQEGEFRTRERRLLgslEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGL 1415
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLE---ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1416 EAELARVEAQRRAAEAQLGGLRSALRRglglgrapspaprpvpgspardaaaggsgdglsspSNLECSPGSQPPSPGPAT 1495
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEE-----------------------------------ERKRRDKLTEEYAELKEE 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1496 SpappdldpETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEArrsvdgrls 1575
Cdd:TIGR02169  366 L--------EDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAA--------- 428

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1576 gvqaemalqeesvrrsereRRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLE 1655
Cdd:TIGR02169  429 -------------------IAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1656 LQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAK--VEESEGALRDKVRGLTE 1733
Cdd:TIGR02169  490 RELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvVVEDDAVAKEAIELLKR 569

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1734 ALA-----------QSSASLNSTQDKNLHLQKALTACEHDRQ------------VLQERLDAARQALSEAR--------- 1781
Cdd:TIGR02169  570 RKAgratflplnkmRDERRDLSILSEDGVIGFAVDLVEFDPKyepafkyvfgdtLVVEDIEAARRLMGKYRmvtlegelf 649

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1782 -KQSSSLGEQVQTLRGEVADL----ELQQVEAE-GQLQQLREVLRQRQ-EGEAAALHMVQKLQDERRLLQERLGSLQRAL 1854
Cdd:TIGR02169  650 eKSGAMTGGSRAPRGGILFSRsepaELQRLRERlEGLKRELSSLQSELrRIENRLDELSQELSDASRKIGEIEKEIEQLE 729

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1855 AQLEAEKREVERSALRL---EKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAEL-----ELAEAQRQIQQ 1926
Cdd:TIGR02169  730 QEEEKLKERLEELEEDLsslEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIpeiqaELSKLEEEVSR 809

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1927 LEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERT----------LEARERAHRQRVRGLEEQVSTLKG 1996
Cdd:TIGR02169  810 IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEienlngkkeeLEEELEELEAALRDLESRLGDLKK 889


                   .
gi 1622834689 1997 Q 1997
Cdd:TIGR02169  890 E 890
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 702-1374 1.95e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 1.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  702 EKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSA----LNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAE 777
Cdd:TIGR00618  185 EFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKelkhLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQ 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  778 QEATVareeqerleelrleqevarQGLEGSLRVAEQAQEVLEQQlptlrhersRLQEQLAQLSRQLSGREQELEQARRAA 857
Cdd:TIGR00618  265 LRARI-------------------EELRAQEAVLEETQERINRA---------RKAAPLAAHIKAVTQIEQQAQRIHTEL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  858 QRQMEALERAAREKEALAKERAGLAVQlaaaEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQlearREHLEAEGQAL 937
Cdd:TIGR00618  317 QSKMRSRAKLLMKRAAHVKQQSSIEEQ----RRLLQTLHSQEIHIRDAHEVATSIREISCQQHTL----TQHIHTLQQQK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  938 LLAKETLtgelaglrqqiiaiQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ 1017
Cdd:TIGR00618  389 TTLTQKL--------------QSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1018 SQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKR 1097
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGE 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1098 DAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRREL 1177
Cdd:TIGR00618  535 QTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQ 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1178 LEAQRKLRESQEGREV-QRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTA 1256
Cdd:TIGR00618  615 HALLRKLQPEQDLQDVrLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTY 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1257 VGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLalgERAEKESRRETLGLRQRLLKGEA 1336
Cdd:TIGR00618  695 WKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKEL---MHQARTVLKARTEAHFNNNEEVT 771

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 1622834689 1337 SLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEAR 1374
Cdd:TIGR00618  772 AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIG 809
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
528-932 1.97e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.13  E-value: 1.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  528 LHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQR---LRDKTDGAMQAQEDAQREVQRLRSANELLSRe 604
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKElkeLKEKAEEYIKLSEFYEEYLDELREIEKRLSR- 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  605 KSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEE---EQEDAVQDGARVRR-ELERSHRQLEQLEGKRSVLAK 680
Cdd:PRK03918   319 LEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEErheLYEEAKAKKEELERlKKRLTGLTPEKLEKELEELEK 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  681 ELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEE---------ASLQDSLSKLSALNESLAQD 751
Cdd:PRK03918   399 AKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkelleeytAELKRIEKELKEIEEKERKL 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  752 KLDLNRLVAQLEEEKAALQGRQ-----RQAEQEATVAREEQERLEELRLEQEVAR-QGLEGSLRVAE---QAQEVLEQQL 822
Cdd:PRK03918   479 RKELRELEKVLKKESELIKLKElaeqlKELEEKLKKYNLEELEKKAEEYEKLKEKlIKLKGEIKSLKkelEKLEELKKKL 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  823 PTLRHERSRLQEQLAQLSRQLS-----------GREQELE-------QARRAAQRQMEALERAAREKEALAKERAGLAVQ 884
Cdd:PRK03918   559 AELEKKLDELEEELAELLKELEelgfesveeleERLKELEpfyneylELKDAEKELEREEKELKKLEEELDKAFEELAET 638

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622834689  885 LAAAEREGRTLS--------EEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEA 932
Cdd:PRK03918   639 EKRLEELRKELEelekkyseEEYEELREEYLELSRELAGLRAELEELEKRREEIKK 694
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
845-1024 2.12e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 42.94  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  845 GREQeLEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEAlegslFEVQRQLAQLE 924
Cdd:COG2268    190 GRRK-IAEIIRDARIAEAEAERETEIAIAQANREAEEAELEQEREIETARIAEAEAELAKKKAE-----ERREAETARAE 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  925 ARREHLEAEGQALLLAKETLTgelAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEA 1004
Cdd:COG2268    264 AEAAYEIAEANAEREVQRQLE---IAEREREIELQEKEAEREEAELEADVRKPAEAEKQAAEAEAEAEAEAIRAKGLAEA 340

                          170       180
                   ....*....|....*....|
gi 1622834689 1005 AWRELEAERAQLQSQLQREQ 1024
Cdd:COG2268    341 EGKRALAEAWNKLGDAAILL 360
PRK11281 PRK11281
mechanosensitive channel MscK;
9-257 2.17e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.36  E-value: 2.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689    9 QDVELTLETVIQTlessvlcQEKGLGTRDLAQdaQTTSLPARIREIVTRNLSWPESPVPLPATEMASLLSLQEENQL--- 85
Cdd:PRK11281    63 QDLEQTLALLDKI-------DRQKEETEQLKQ--QLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLaqt 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689   86 ------LQQELSRVEDLL--AQSRAERDELAIKYNavSERLEQTLRLESGELETQEPrglvrQSVELRRQLQEEQA---- 153
Cdd:PRK11281   134 ldqlqnAQNDLAEYNSQLvsLQTQPERAQAALYAN--SQRLQQIRNLLKGGKVGGKA-----LRPSQRVLLQAEQAllna 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  154 --SYRRKLQA--------YQ-------EGQQRQAQLVQRLQGKILQykKRCSELEQQLLE-RSGELEQQRLRNTEHSQDL 215
Cdd:PRK11281   207 qnDLQRKSLEgntqlqdlLQkqrdyltARIQRLEHQLQLLQEAINS--KRLTLSEKTVQEaQSQDEAARIQANPLVAQEL 284

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1622834689  216 ESALI---RLEEEQQRSASLAQVNAMLREQLDQAGLANQALSEDI 257
Cdd:PRK11281   285 EINLQlsqRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQI 329
PRK11281 PRK11281
mechanosensitive channel MscK;
731-1004 2.55e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.98  E-value: 2.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  731 EASLQDSLSKLSALNESLAQDKL---DLN---RLVAQLEEEKAALQGRQRQAEQ-EATVAREEQERLEELRLEQEVARQG 803
Cdd:PRK11281    38 EADVQAQLDALNKQKLLEAEDKLvqqDLEqtlALLDKIDRQKEETEQLKQQLAQaPAKLRQAQAELEALKDDNDEETRET 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  804 LEgSLRVAEqaqevLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRA---AQRQMEALERaarekealakerag 880
Cdd:PRK11281   118 LS-TLSLRQ-----LESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAAlyaNSQRLQQIRN-------------- 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  881 lavQLAAAEREGRTLSEEA-TRLRLEKEALEgslfevqrqlAQLEARREHLEAEG--QALLLAK-ETLTGELAGLRQQII 956
Cdd:PRK11281   178 ---LLKGGKVGGKALRPSQrVLLQAEQALLN----------AQNDLQRKSLEGNTqlQDLLQKQrDYLTARIQRLEHQLQ 244

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1622834689  957 AIQEkasldkELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEA 1004
Cdd:PRK11281   245 LLQE------AINSKRLTLSEKTVQEAQSQDEAARIQANPLVAQELEI 286
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
565-874 2.60e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.58  E-value: 2.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  565 ALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLE 644
Cdd:COG4372     28 ALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQ 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  645 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSM 724
Cdd:COG4372    108 EEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDE 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  725 TKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGL 804
Cdd:COG4372    188 LLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAI 267

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  805 EGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEAL 874
Cdd:COG4372    268 LVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLA 337
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1600-1938 2.60e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.70  E-value: 2.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1600 DQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQA 1679
Cdd:TIGR04523   96 DKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENEL 175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1680 QALQDRVDSLQRQVADS-------EVKAGTLQLTVERLNGALAKVEEsegaLRDKVRGLTEALAQSSASLNSTQDKNLHL 1752
Cdd:TIGR04523  176 NLLEKEKLNIQKNIDKIknkllklELLLSNLKKKIQKNKSLESQISE----LKKQNNQLKDNIEKKQQEINEKTTEISNT 251

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1753 QKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLElqQVEAEGQLQQLREVLRQRQEgeaaalhM 1832
Cdd:TIGR04523  252 QTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN--NQKEQDWNKELKSELKNQEK-------K 322

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1833 VQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTG 1912
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQN 402

                          330       340
                   ....*....|....*....|....*.
gi 1622834689 1913 AELELAEAQRQIQQLEAQVVVLEQSH 1938
Cdd:TIGR04523  403 QEKLNQQKDEQIKKLQQEKELLEKEI 428
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 619-1434 2.60e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.02  E-value: 2.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  619 AEELRQEREKLQAAQEELRRQRDRLEEEQEdavqdgarvrrELERSHRQLEQLEGKRSVLAKELVEVREALSRatLQRDM 698
Cdd:COG3096    277 ANERRELSERALELRRELFGARRQLAEEQY-----------RLVEMARELEELSARESDLEQDYQAASDHLNL--VQTAL 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  699 LQAEKAEVAEAltkaeagrvELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQ 778
Cdd:COG3096    344 RQQEKIERYQE---------DLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQ 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  779 --EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE----VLEQQLPTLRHERSRLqEQLAQLSRQLSGreqelEQ 852
Cdd:COG3096    415 yqQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATeevlELEQKLSVADAARRQF-EKAYELVCKIAG-----EV 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  853 ARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLsEEATRLRLEKEALEG----SLFEVQRQLAQLEARRE 928
Cdd:COG3096    489 ERSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQ-QNAERLLEEFCQRIGqqldAAEELEELLAELEAQLE 567

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  929 HLEAEgqalllaKETLTGELAGLRQQIIAIQEKAsldKELMAQKLV-QAEREAQASLREQRAAHEEDLQRLQrekEAAWR 1007
Cdd:COG3096    568 ELEEQ-------AAEAVEQRSELRQQLEQLRARI---KELAARAPAwLAAQDALERLREQSGEALADSQEVT---AAMQQ 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1008 ELEAERA--QLQSQLQREQEELLARLEAEKEELSEEIATLQQ--ERDEGLLLAESEKQQALSlkesEKTALSEKLMGTRH 1083
Cdd:COG3096    635 LLEREREatVERDELAARKQALESQIERLSQPGGAEDPRLLAlaERLGGVLLSEIYDDVTLE----DAPYFSALYGPARH 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1084 SLATISLEMERQK---------------RDAQS-------RQEQDRSTV---------------------NALTSELRDL 1120
Cdd:COG3096    711 AIVVPDLSAVKEQlagledcpedlylieGDPDSfddsvfdAEELEDAVVvklsdrqwrysrfpevplfgrAAREKRLEEL 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1121 RAQLEEAVAAHAQ---EVRRLQEQAQD----LGKQRDSCLREAEElrTQLRLLEDARDGLRRELLEAQRKLRESQEGREV 1193
Cdd:COG3096    791 RAERDELAEQYAKasfDVQKLQRLHQAfsqfVGGHLAVAFAPDPE--AELAALRQRRSELERELAQHRAQEQQLRQQLDQ 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1194 QRQEAGELRRSLGE-GAKEREALRRSNEELRAAVKKAESERISLKLanedKEQKLALLEEARTAVGKEAgelrTGLQEVE 1272
Cdd:COG3096    869 LKEQLQLLNKLLPQaNLLADETLADRLEELREELDAAQEAQAFIQQ----HGKALAQLEPLVAVLQSDP----EQFEQLQ 940

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1273 RSRLEARRELQELRRQMKMLDsentrlgrELAELQGRLALGERAEKESRRETLG--LRQRLLKGEASlevmRQELQVAQR 1350
Cdd:COG3096    941 ADYLQAKEQQRRLKQQIFALS--------EVVQRRPHFSYEDAVGLLGENSDLNekLRARLEQAEEA----RREAREQLR 1008

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1351 KLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAA-----ELGLRLSAAEGRAQGLEAELARVEAQ 1425
Cdd:COG3096   1009 QAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEERArirrdELHEELSQNRSRRSQLEKQLTRCEAE 1088


                   ....*....
gi 1622834689 1426 RRAAEAQLG 1434
Cdd:COG3096   1089 MDSLQKRLR 1097
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1766-1930 2.64e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 2.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1766 LQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQE 1845
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1846 RLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLtgAELELAEAQRQIQ 1925
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL--QALSEAEAEQALD 186


                   ....*
gi 1622834689 1926 QLEAQ 1930
Cdd:COG4372    187 ELLKE 191
PRK09039 PRK09039
peptidoglycan -binding protein;
1285-1432 2.74e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.26  E-value: 2.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1285 LRRQMKMLDSENTRLGRELAELQGRLALgERAEKESRRETLGlrqRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRER 1364
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLLSL-ERQGNQDLQDSVA---NLRASLSAAEAERSRLQALLAELAGAGAAAEGRAG 119

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834689 1365 RLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQ 1432
Cdd:PRK09039   120 ELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRESQAKIADLGRRLNVALAQ 187
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1015-1427 2.87e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.89  E-value: 2.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1015 QLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAE--SEKQQALSLKESEKTALSEKLMGTRHSLATISLEM 1092
Cdd:pfam10174  338 QRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGeiRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQL 417

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1093 ERQKRDAQSRQEQDRSTVNALTSelrdlraqLEEAVAAHAQEVRRLQEQAQDLGKQRdscLREAEELRTQLRLLEDARDG 1172
Cdd:pfam10174  418 AGLKERVKSLQTDSSNTDTALTT--------LEEALSEKERIIERLKEQREREDRER---LEELESLKKENKDLKEKVSA 486

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1173 LRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKlANEDKEQKLALLEe 1252
Cdd:pfam10174  487 LQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVR-TNPEINDRIRLLE- 564

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1253 artavgkeagelrtglQEVERSRLEARRELQELRRQMKML-DSENTRLGRElaelqgrlalgeraEKESRRETLGLRQrl 1331
Cdd:pfam10174  565 ----------------QEVARYKEESGKAQAEVERLLGILrEVENEKNDKD--------------KKIAELESLTLRQ-- 612

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1332 lkgeasleVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGR 1411
Cdd:pfam10174  613 --------MKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQS 684

                          410
                   ....*....|....*.
gi 1622834689 1412 AQGLEAELARVEAQRR 1427
Cdd:pfam10174  685 LAEKDGHLTNLRAERR 700
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1511-1944 2.91e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 2.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1511 LQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQaEMALQEESVRR 1590
Cdd:PRK03918   219 LREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIK 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1591 SERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLEL--QRRSLEGELQRS 1668
Cdd:PRK03918   298 LSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeEAKAKKEELERL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1669 RLGLSDR-----EAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEA-----LAQS 1738
Cdd:PRK03918   378 KKRLTGLtpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEhrkelLEEY 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1739 SASLNStqdknlhLQKALTACEHDRQVLQERLDAARQALSEARKQSS--SLGEQVQTLRGEVADLELQQVEAEGQ----L 1812
Cdd:PRK03918   458 TAELKR-------IEKELKEIEEKERKLRKELRELEKVLKKESELIKlkELAEQLKELEEKLKKYNLEELEKKAEeyekL 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1813 QQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRValrRTLDKVEREKLRS 1892
Cdd:PRK03918   531 KEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL---KELEPFYNEYLEL 607

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622834689 1893 HEDTVRLSAEKGRLD---RTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLE 1944
Cdd:PRK03918   608 KDAEKELEREEKELKkleEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYE 662
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1209-1463 3.41e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1209 AKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRrq 1288
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK-- 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1289 mkmldsentrlgrelAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLG 1368
Cdd:COG4942    104 ---------------EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD-LAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1369 SLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRR---GLG 1445
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAErtpAAG 247

                          250
                   ....*....|....*...
gi 1622834689 1446 LGRAPSPAPRPVPGSPAR 1463
Cdd:COG4942    248 FAALKGKLPWPVSGRVVR 265
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1511-1744 3.44e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1511 LQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRr 1590
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA- 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1591 sererratlDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRL 1670
Cdd:COG4942    108 ---------ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834689 1671 GLSDREAQAQALQDRVDSLQRQVADsevkagtLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNS 1744
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLAR-------LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 688-1031 3.61e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.35  E-value: 3.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  688 ALSRATLQRDMLQAE------KAEVAEALTKAEAGRVELELSMTKLRAEEASLqDSLSKLSA------LNESLAQDKLDL 755
Cdd:PRK10929    22 APDEKQITQELEQAKaaktpaQAEIVEALQSALNWLEERKGSLERAKQYQQVI-DNFPKLSAelrqqlNNERDEPRSVPP 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  756 NRLVAQLEEE----KAALQGRQRQAEQEATVAREEQERLEELRLEQEVAR----------QGLEGSLRVAEQAQEVLEQQ 821
Cdd:PRK10929   101 NMSTDALEQEilqvSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARrqlneierrlQTLGTPNTPLAQAQLTALQA 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  822 LPTLRheRSRLQE-QLAQLS---RQ-LSGREQELEQARRA--------------AQRQMEAlERAAREKEALAKERAGLA 882
Cdd:PRK10929   181 ESAAL--KALVDElELAQLSannRQeLARLRSELAKKRSQqldaylqalrnqlnSQRQREA-ERALESTELLAEQSGDLP 257

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  883 VQLAAAEREGRTLSEEatrlrLEKEALEGSLF-EVQRQLAQ--LEARREHLEAEGQALLLAKETLTGElaGLRQQIIAIQ 959
Cdd:PRK10929   258 KSIVAQFKINRELSQA-----LNQQAQRMDLIaSQQRQAASqtLQVRQALNTLREQSQWLGVSNALGE--ALRAQVARLP 330

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622834689  960 EKAsldkelmaqKLVQAEREaQASLREQRAAHEEDLQRLQRE---KEAAWRELEAERAQLQSQLQREQEELLARL 1031
Cdd:PRK10929   331 EMP---------KPQQLDTE-MAQLRVQRLRYEDLLNKQPQLrqiRQADGQPLTAEQNRILDAQLRTQRELLNSL 395
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 617-1285 4.78e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 4.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  617 QQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLE----------QLEGKRSVLAKELVEVR 686
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETElcaeaeemraRLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  687 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 766
Cdd:pfam01576   82 SRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERI 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  767 AALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGR 846
Cdd:pfam01576  162 SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKK 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  847 EQELEQA----------RRAAQRQMEALERAARE-KEALAKERAglavQLAAAEREGRTLSEEATRLRLEKEALEGSLFE 915
Cdd:pfam01576  242 EEELQAAlarleeetaqKNNALKKIRELEAQISElQEDLESERA----ARNKAEKQRRDLGEELEALKTELEDTLDTTAA 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  916 VQrqlaQLEARREhleaegQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEReAQASLREQRAAHEEDL 995
Cdd:pfam01576  318 QQ----ELRSKRE------QEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKR-NKANLEKAKQALESEN 386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  996 QRLQREK---EAAWRELEAERAQLQSQLQreqeELLARLEAEKEELSEEiatlqqerdeglllaeSEKQQALSLKESEKT 1072
Cdd:pfam01576  387 AELQAELrtlQQAKQDSEHKRKKLEGQLQ----ELQARLSESERQRAEL----------------AEKLSKLQSELESVS 446

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1073 ALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDL---RAQLEEAVAAHAQEVRRLQEQAQDLGKQR 1149
Cdd:pfam01576  447 SLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLedeRNSLQEQLEEEEEAKRNVERQLSTLQAQL 526

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1150 DSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKK- 1228
Cdd:pfam01576  527 SDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKf 606

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622834689 1229 ----AESERISLKLANE-DKEQKLALLEEART-AVGKEAGELRTGLQEVERSRLEARRELQEL 1285
Cdd:pfam01576  607 dqmlAEEKAISARYAEErDRAEAEAREKETRAlSLARALEEALEAKEELERTNKQLRAEMEDL 669
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
808-1016 4.93e-03

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 41.60  E-value: 4.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  808 LRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSR-QLS-GREQELEQARR---AAQRQMEALERAArekEALAKERAGLA 882
Cdd:COG0497    167 WRALKKELEELRADEAERARELDLLRFQLEELEAaALQpGEEEELEEERRrlsNAEKLREALQEAL---EALSGGEGGAL 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  883 VQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALllakETLTGELAGLRQ--------- 953
Cdd:COG0497    244 DLLGQALRALERLAEYDPSLAELAERLESALIELEEAASELRRYLDSLEFDPERL----EEVEERLALLRRlarkygvtv 319

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834689  954 -QIIAIQEKasldkelMAQKLVQAEreaqaslreqraAHEEDLQRLQREKEAAWRELEAERAQL 1016
Cdd:COG0497    320 eELLAYAEE-------LRAELAELE------------NSDERLEELEAELAEAEAELLEAAEKL 364
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
541-1233 5.09e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 5.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  541 RYEASQDLLGTLRKQLsdsESERRALEEQLQRlrdktdgamqaQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAE 620
Cdd:PRK03918   159 DYENAYKNLGEVIKEI---KRRIERLEKFIKR-----------TENIEELIKEKEKELEEVLREINEISSELPELREELE 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  621 ELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVrRELErshRQLEQLEGKRSVLAKELVEVREALSRATlqrdmlq 700
Cdd:PRK03918   225 KLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKI-RELE---ERIEELKKEIEELEEKVKELKELKEKAE------- 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  701 aEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQdkldLNRLVAQLEEEKAALQGRQRQAEqea 780
Cdd:PRK03918   294 -EYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE----LKKKLKELEKRLEELEERHELYE--- 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  781 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSgreqELEQARRAAQRQ 860
Cdd:PRK03918   366 EAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIE----ELKKAKGKCPVC 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  861 MEALERAAReKEALAKERAglavQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLA 940
Cdd:PRK03918   442 GRELTEEHR-KELLEEYTA----ELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYN 516

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  941 KETLtgelaglrqqiiaiqEKASLDKELMAQKLvqAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQL 1020
Cdd:PRK03918   517 LEEL---------------EKKAEEYEKLKEKL--IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKEL 579

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1021 QREQEELLARLeaekeelSEEIATLQQERDEGLLL--AESEKQQALSLKESEKTALS---EKLMGTRHSLATISLEMER- 1094
Cdd:PRK03918   580 EELGFESVEEL-------EERLKELEPFYNEYLELkdAEKELEREEKELKKLEEELDkafEELAETEKRLEELRKELEEl 652

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1095 QKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAvaahaqeVRRLQEQAQDLGKQRDScLREAEELRTQLRLLEDARDGLr 1174
Cdd:PRK03918   653 EKKYSEEEYEELREEYLELSRELAGLRAELEEL-------EKRREEIKKTLEKLKEE-LEEREKAKKELEKLEKALERV- 723

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622834689 1175 RELLEAQRKLRESQEGREVQRQE--AGELRRSLGEGAKEREALRRSNEELRAAVKKAESER 1233
Cdd:PRK03918   724 EELREKVKKYKALLKERALSKVGeiASEIFEELTEGKYSGVRVKAEENKVKLFVVYQGKER 784
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 830-1072 5.24e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.84  E-value: 5.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  830 SRLQE----QLAQLSRQLSGreQELEQARRAAQRQMEALE--RAAREKEALAKERAGlavqlaaaEREGRTLSEEATRLR 903
Cdd:PRK05771    23 EALHElgvvHIEDLKEELSN--ERLRKLRSLLTKLSEALDklRSYLPKLNPLREEKK--------KVSVKSLEELIKDVE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  904 LEKEALEGSLFEVQRQLAQLEARREHLEAEGQAL------------LLAKETLTGELAGL--RQQIIAIQEKASLDKELM 969
Cdd:PRK05771    93 EELEKIEKEIKELEEEISELENEIKELEQEIERLepwgnfdldlslLLGFKYVSVFVGTVpeDKLEELKLESDVENVEYI 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  970 AQK------LVQAEREAQASLREQRAAHEEDLQRLQREKEAAwRELEAERAQLqSQLQREQEELLARLEAEKEELSEEIA 1043
Cdd:PRK05771   173 STDkgyvyvVVVVLKELSDEVEEELKKLGFERLELEEEGTPS-ELIREIKEEL-EEIEKERESLLEELKELAKKYLEELL 250

                          250       260       270
                   ....*....|....*....|....*....|
gi 1622834689 1044 TLqqerdEGLLLAESEKQQALS-LKESEKT 1072
Cdd:PRK05771   251 AL-----YEYLEIELERAEALSkFLKTDKT 275
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1762-2010 5.51e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 5.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1762 DRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAAlHMVQKLQDERR 1841
Cdd:COG3096    279 ERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQ-EKIERYQEDLE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1842 LLQERL--GSLQRALAQLEAEKREVERSALRLEKDRVA-----LRRTLDKVEREKLRSHEDTVRLSAEKGRL---DRTLT 1911
Cdd:COG3096    358 ELTERLeeQEEVVEEAAEQLAEAEARLEAAEEEVDSLKsqladYQQALDVQQTRAIQYQQAVQALEKARALCglpDLTPE 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1912 GAELELAEAQRQIQQLEAQVVVLEQSHSPAQL---EVDAQQQQHLELQQEVERLRSAQVQTERTLEARE-RAHRQRVRGL 1987
Cdd:COG3096    438 NAEDYLAAFRAKEQQATEEVLELEQKLSVADAarrQFEKAYELVCKIAGEVERSQAWQTARELLRRYRSqQALAQRLQQL 517

                          250       260
                   ....*....|....*....|....*
gi 1622834689 1988 EEQVSTLKGQL--QQELRRSSAPFS 2010
Cdd:COG3096    518 RAQLAELEQRLrqQQNAERLLEEFC 542
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 971-1068 6.12e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.61  E-value: 6.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  971 QKLVQAEREAQASLREQRAAHEEDLQRLQREKEaawrELEAERAQLQSQLQREQEEL--LARLEAEKEELSEEIATLQQE 1048
Cdd:COG0542    418 RRLEQLEIEKEALKKEQDEASFERLAELRDELA----ELEEELEALKARWEAEKELIeeIQELKEELEQRYGKIPELEKE 493

                           90       100
                   ....*....|....*....|
gi 1622834689 1049 RDEgllLAESEKQQALSLKE 1068
Cdd:COG0542    494 LAE---LEEELAELAPLLRE 510
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1511-2000 6.78e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.54  E-value: 6.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1511 LQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAErdhaTLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRR 1590
Cdd:TIGR04523  175 LNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKK----IQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISN 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1591 SERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELqrRSLEGELQRSRL 1670
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSEL--KNQEKKLEEIQN 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1671 GLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTealaqssaslNSTQDKNL 1750
Cdd:TIGR04523  329 QISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLE----------SQINDLES 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1751 HLQKAltacEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAAL 1830
Cdd:TIGR04523  399 KIQNQ----EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLS 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1831 HMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTL 1910
Cdd:TIGR04523  475 RSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFEL 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1911 TGAELE--LAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHR---QRVR 1985
Cdd:TIGR04523  555 KKENLEkeIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEklsSIIK 634

                          490
                   ....*....|....*
gi 1622834689 1986 GLEEQVSTLKGQLQQ 2000
Cdd:TIGR04523  635 NIKSKKNKLKQEVKQ 649
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 531-751 6.90e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.58  E-value: 6.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  531 RQLQVQDMRGRyEASqDLLGTLRKQLSDSeseRRALEEQLQRLRDKTDG----------AMQAQEDAQR----------- 589
Cdd:PRK10929   123 RQAQQEQDRAR-EIS-DSLSQLPQQQTEA---RRQLNEIERRLQTLGTPntplaqaqltALQAESAALKalvdelelaql 197

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  590 ------EVQRLRSanELLSREKSNLAHSLQVAQQQAEELRQ-EREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELE 662
Cdd:PRK10929   198 sannrqELARLRS--ELAKKRSQQLDAYLQALRNQLNSQRQrEAERALESTELLAEQSGDLPKSIVAQFKINRELSQALN 275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  663 RSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAeVAEALtKAEAGRV-------ELELSMTKLRAEEASLQ 735
Cdd:PRK10929   276 QQAQRMDLIASQQRQAASQTLQVRQALNTLREQSQWLGVSNA-LGEAL-RAQVARLpempkpqQLDTEMAQLRVQRLRYE 353

                          250
                   ....*....|....*.
gi 1622834689  736 DSLSKLSALNESLAQD 751
Cdd:PRK10929   354 DLLNKQPQLRQIRQAD 369
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
 277-811 7.15e-03

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 41.40  E-value: 7.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  277 AWRREEesfnayfsnehsrllLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRTEAA 356
Cdd:COG3321    867 PFQRED---------------AAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLA 931

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  357 LEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRLQ 436
Cdd:COG3321    932 LVALAAAAAALLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALL 1011

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  437 EQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASDGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACS 516
Cdd:COG3321   1012 LAAAAAAAALLALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALA 1091

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  517 DSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRS 596
Cdd:COG3321   1092 AAALALALAALAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAA 1171

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  597 ANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRS 676
Cdd:COG3321   1172 ALLLALALALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAA 1251

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  677 VLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN 756
Cdd:COG3321   1252 AAALLAALAALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALA 1331

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622834689  757 RLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVA 811
Cdd:COG3321   1332 ALAAAVAAALALAAAAAAAAAAAAAAAAAAALAAAAGAAAAAAALALAALAAAVA 1386
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1512-1990 7.29e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.36  E-value: 7.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1512 QEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSvdgRLSGVQAEMALQEESVRrs 1591
Cdd:pfam12128  290 QLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQE---QLPSWQSELENLEERLK-- 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1592 ererrATLDQIATLERSLQATESelRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQ-RRSLEGELQRSRL 1670
Cdd:pfam12128  365 -----ALTGKHQDVTAKYNRRRS--KIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESElREQLEAGKLEFNE 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1671 GLSDREAQAQALQDRVDSLQrqvADSEVKAgTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNL 1750
Cdd:pfam12128  438 EEYRLKSRLGELKLRLNQAT---ATPELLL-QLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASR 513

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1751 HLQKALTACEHdrqvLQERLDAARQAL-----SEARKQSSSLGEQVQT-------LRGEVAD-------------LELQQ 1805
Cdd:pfam12128  514 RLEERQSALDE----LELQLFPQAGTLlhflrKEAPDWEQSIGKVISPellhrtdLDPEVWDgsvggelnlygvkLDLKR 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1806 VEAEGQLQQLREVLRQRQEGEAAalhmvqkLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKV 1885
Cdd:pfam12128  590 IDVPEWAASEEELRERLDKAEEA-------LQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEK 662

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1886 EREKLRSHEDTVRlsaekgrldrtltgaelELAEAQRQIQQLEAQVVVLEQSHSPAQLEVD-----AQQQQHLELQQEVE 1960
Cdd:pfam12128  663 QSEKDKKNKALAE-----------------RKDSANERLNSLEAQLKQLDKKHQAWLEEQKeqkreARTEKQAYWQVVEG 725

                          490       500       510
                   ....*....|....*....|....*....|
gi 1622834689 1961 RLRSAQVQTERTLEARERAHRQRVRGLEEQ 1990
Cdd:pfam12128  726 ALDAQLALLKAAIAARRSGAKAELKALETW 755
PRK09039 PRK09039
peptidoglycan -binding protein;
1708-1816 7.52e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 40.72  E-value: 7.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1708 ERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQER-------LDAARQALSEA 1780
Cdd:PRK09039    56 DRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRagelaqeLDSEKQVSARA 135

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1622834689 1781 RKQSSSLGEQVQTLRGEVADLE--LQQVEAEGQLQQLR 1816
Cdd:PRK09039   136 LAQVELLNQQIAALRRQLAALEaaLDASEKRDRESQAK 173
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 637-932 8.60e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 8.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  637 RRQRDRLEE-EQEDAVQDGARVRRELERsHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMlqaEKAEVAEALTKAEA 715
Cdd:pfam17380  287 RQQQEKFEKmEQERLRQEKEEKAREVER-RRKLEEAEKARQAEMDRQAAIYAEQERMAMERER---ELERIRQEERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  716 GRV---ELELSMTKLRAEEASLQDSLSKlsalNESLAQDkLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEE 792
Cdd:pfam17380  363 ERIrqeEIAMEISRMRELERLQMERQQK----NERVRQE-LEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREV 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  793 LRLEQEVARQglegSLRVAEQAQEvLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKE 872
Cdd:pfam17380  438 RRLEEERARE----MERVRLEEQE-RQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEE 512

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622834689  873 ALAK--ERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEgslfEVQRQLAQLEARREHLEA 932
Cdd:pfam17380  513 RKRKllEKEMEERQKAIYEEERRREAEEERRKQQEMEERR----RIQEQMRKATEERSRLEA 570
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 816-1440 8.89e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.16  E-value: 8.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  816 EVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTL 895
Cdd:TIGR04523   78 KILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKL 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  896 SEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEgqalLLAKETLtgelaglrqqIIAIQEKASLDKELMAQKLvq 975
Cdd:TIGR04523  158 NNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNK----LLKLELL----------LSNLKKKIQKNKSLESQIS-- 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  976 aereaqaSLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQsQLQREQEELLARLEAEkeelseeiaTLQQERDEGLLl 1055
Cdd:TIGR04523  222 -------ELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLN-QLKDEQNKIKKQLSEK---------QKELEQNNKKI- 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1056 aeSEKQQALSLKESEKTAL-SEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQE 1134
Cdd:TIGR04523  284 --KELEKQLNQLKSEISDLnNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEK 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1135 VRRLQE---QAQDLGKQRDSCLREAEELRTQLRLLEdardglrRELLEAQRKLRESQEGREVQRQEAGELRrslgegaKE 1211
Cdd:TIGR04523  362 QRELEEkqnEIEKLKKENQSYKQEIKNLESQINDLE-------SKIQNQEKLNQQKDEQIKKLQQEKELLE-------KE 427

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1212 REALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERsrlearrELQELRRQMKM 1291
Cdd:TIGR04523  428 IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK-------ELKSKEKELKK 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1292 LDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRtrerrllgsLE 1371
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKE---------IE 571

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834689 1372 EARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSAL 1440
Cdd:TIGR04523  572 ELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKK 640
COG5283 COG5283
Phage-related tail protein [Mobilome: prophages, transposons];
548-648 8.98e-03

Phage-related tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444094 [Multi-domain]  Cd Length: 747  Bit Score: 40.99  E-value: 8.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  548 LLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVA----QQQAEELR 623
Cdd:COG5283      8 VDKPFKSALESAKQRVAALAQALKALEAPTRALARALERAKQAAARLQTKYNKLRQSLQRLRQALDQAgidtRQLSAAQR 87

                           90       100
                   ....*....|....*....|....*
gi 1622834689  624 QEREKLQAAQEELRRQRDRLEEEQE 648
Cdd:COG5283     88 RLRSSLEQTNRQLERQQQRLARLGA 112
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1763-2004 9.20e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.09  E-value: 9.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1763 RQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQqveAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRL 1842
Cdd:COG3096    845 RSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLL---ADETLADRLEELREELDAAQEAQAFIQQHGKALAQ 921

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1843 LQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKG----RLDRTLTGAELELA 1918
Cdd:COG3096    922 LEPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGENSdlneKLRARLEQAEEARR 1001

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1919 EAQRQIQQLEAQV-------VVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERT-LEARERAHRQRVRGLEEQ 1990
Cdd:COG3096   1002 EAREQLRQAQAQYsqynqvlASLKSSRDAKQQTLQELEQELEELGVQADAEAEERARIRRDeLHEELSQNRSRRSQLEKQ 1081

                          250
                   ....*....|....*..
gi 1622834689 1991 VSTLKG---QLQQELRR 2004
Cdd:COG3096   1082 LTRCEAemdSLQKRLRK 1098
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 966-1306 9.31e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 40.65  E-value: 9.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  966 KELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEEL------LARLEAEKEELS 1039
Cdd:pfam07888   28 RAELLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELrqsrekHEELEEKYKELS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1040 EEIATLQQERDeGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER---QKRDAQSRQEQDRSTVNALTSE 1116
Cdd:pfam07888  108 ASSEELSEEKD-ALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKagaQRKEEEAERKQLQAKLQQTEEE 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1117 LRDLRAQLEEAVAAHAQ---EVRRLQE----------QAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRK 1183
Cdd:pfam07888  187 LRSLSKEFQELRNSLAQrdtQVLQLQDtittltqkltTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQ 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1184 LRESQEGREVQRQEAGELRRSLGE-GAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAG 1262
Cdd:pfam07888  267 RDRTQAELHQARLQAAQLTLQLADaSLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEV 346

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1622834689 1263 ELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAEL 1306
Cdd:pfam07888  347 ELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQEL 390
KpsE COG3524
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
1760-1868 9.58e-03

Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442746 [Multi-domain]  Cd Length: 370  Bit Score: 40.60  E-value: 9.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1760 EHDRQVLQERLDAARQALSEARKQSS--SLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQegeaaalHMVQKLQ 1837
Cdd:COG3524    183 EEEVERAEERLRDAREALLAFRNRNGilDPEATAEALLQLIATLEGQLAELEAELAALRSYLSPNS-------PQVRQLR 255

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1622834689 1838 DERRLLQERLGSLQRALAQLEAEKREVERSA 1868
Cdd:COG3524    256 RRIAALEKQIAAERARLTGASGGDSLASLLA 286
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 849-1230 9.63e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 40.65  E-value: 9.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  849 ELEQARRAAQRQMEA-LERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATrlrlekealegslfEVQRQLAQLEARR 927
Cdd:pfam07888   45 ELLQAQEAANRQREKeKERYKRDREQWERQRRELESRVAELKEELRQSREKHE--------------ELEEKYKELSASS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689  928 EHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKAsLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWR 1007
Cdd:pfam07888  111 EELSEEKDALLAQRAAHEARIRELEEDIKTLTQRV-LERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRS 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1008 ELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMgtrhslat 1087
Cdd:pfam07888  190 LSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELS-------- 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834689 1088 islEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQdlgKQRDSCLREAEELRTQLRLLE 1167
Cdd:pfam07888  262 ---SMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAE---ADKDRIEKLSAELQRLEERLQ 335

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622834689 1168 DARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAE 1230
Cdd:pfam07888  336 EERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLE 398
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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