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Conserved domains on  [gi|967261784|ref|XP_014976158|]
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lambda-crystallin homolog isoform X7 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06129 super family cl35428
3-hydroxyacyl-CoA dehydrogenase; Validated
 9-260 3.94e-72

3-hydroxyacyl-CoA dehydrogenase; Validated


The actual alignment was detected with superfamily member PRK06129:

Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 223.38  E-value: 3.94e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGALKGSlSAEEQLSLISGCPNIQEAVEGA 88
Cdd:PRK06129   5 VAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGE-APDAVLARIRVTDSLADAVADA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  89 MHIQ------------------------------------------------------VNPPYYIPLVELVPHPETAPTT 114
Cdd:PRK06129  84 DYVQesapenlelkralfaeldalapphailasstsallasaftehlagrerclvahpINPPYLIPVVEVVPAPWTAPAT 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784 115 VDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNA-EG 193
Cdd:PRK06129 164 LARAEALYRAAGQSPVRLRREIDGFVLNRLQGALLREAFRLVADGVASVDDIDAVIRDGLGLRWSFMGPFETIDLNApGG 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 967261784 194 MLSYCDRYSEGMKHVLKTFGPIPEFSRATAEKVNQDMCVKVPDDpeHLAARRQWRDECLMRLAKLKS 260
Cdd:PRK06129 244 VADYAQRYGPMYRRMAAERGQPVPWDGELVARVEAERRAALPLD--QLAARQAWRDRRLMALAAHRR 308
 
Name Accession Description Interval E-value
PRK06129 PRK06129
3-hydroxyacyl-CoA dehydrogenase; Validated
 9-260 3.94e-72

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 223.38  E-value: 3.94e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGALKGSlSAEEQLSLISGCPNIQEAVEGA 88
Cdd:PRK06129   5 VAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGE-APDAVLARIRVTDSLADAVADA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  89 MHIQ------------------------------------------------------VNPPYYIPLVELVPHPETAPTT 114
Cdd:PRK06129  84 DYVQesapenlelkralfaeldalapphailasstsallasaftehlagrerclvahpINPPYLIPVVEVVPAPWTAPAT 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784 115 VDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNA-EG 193
Cdd:PRK06129 164 LARAEALYRAAGQSPVRLRREIDGFVLNRLQGALLREAFRLVADGVASVDDIDAVIRDGLGLRWSFMGPFETIDLNApGG 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 967261784 194 MLSYCDRYSEGMKHVLKTFGPIPEFSRATAEKVNQDMCVKVPDDpeHLAARRQWRDECLMRLAKLKS 260
Cdd:PRK06129 244 VADYAQRYGPMYRRMAAERGQPVPWDGELVARVEAERRAALPLD--QLAARQAWRDRRLMALAAHRR 308
FadB COG1250
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ...
 9-189 1.27e-48

3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440862 [Multi-domain]  Cd Length: 281  Bit Score: 162.20  E-value: 1.27e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGALKGSlSAEEQLSLISGCPN-------- 80
Cdd:COG1250    5 VAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEE-EADAALARITPTTDlaaladad 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  81 -IQEAV-------------------EGA--------------------------MHIqVNPPYYIPLVELVPHPETAPTT 114
Cdd:COG1250   84 lVIEAVpedldlkqevfaeldavapPDAilasntsslsitelaaatkrperfigLHF-FNPVPLMPLVEVIRGPATSDET 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 967261784 115 VDRTHALMKKIGQCPMRVqKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRyafIGPLETMHL 189
Cdd:COG1250  163 VATAVAFARRLGKTPVVV-KDTPGFIVNRILVPYLNEAIRLLEEGVASPEDIDAAMRLGFGFP---MGPFELADL 233
3HCDH_N pfam02737
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ...
 9-132 3.45e-29

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.


Pssm-ID: 397037 [Multi-domain]  Cd Length: 180  Bit Score: 108.78  E-value: 3.45e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784    9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGALKGSlSAEEQLSLISGCPNIQEAVE-- 86
Cdd:pfam02737   2 VAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERLVEKGRITEE-EVDAALARISFTTDLAAAVDad 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   87 ----------------------------------------------------GAMHIqVNPPYYIPLVELVPHPETAPTT 114
Cdd:pfam02737  81 lvieavpenlelkrklfaeldaiappdailatntsslsitelaaatkrperfIGLHF-FNPPPLMPLVEVVRGEKTSPET 159

                         170
                  ....*....|....*...
gi 967261784  115 VDRTHALMKKIGQCPMRV 132
Cdd:pfam02737 160 VATTVELAKKIGKTPVVV 177
 
Name Accession Description Interval E-value
PRK06129 PRK06129
3-hydroxyacyl-CoA dehydrogenase; Validated
 9-260 3.94e-72

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 223.38  E-value: 3.94e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGALKGSlSAEEQLSLISGCPNIQEAVEGA 88
Cdd:PRK06129   5 VAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGE-APDAVLARIRVTDSLADAVADA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  89 MHIQ------------------------------------------------------VNPPYYIPLVELVPHPETAPTT 114
Cdd:PRK06129  84 DYVQesapenlelkralfaeldalapphailasstsallasaftehlagrerclvahpINPPYLIPVVEVVPAPWTAPAT 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784 115 VDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNA-EG 193
Cdd:PRK06129 164 LARAEALYRAAGQSPVRLRREIDGFVLNRLQGALLREAFRLVADGVASVDDIDAVIRDGLGLRWSFMGPFETIDLNApGG 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 967261784 194 MLSYCDRYSEGMKHVLKTFGPIPEFSRATAEKVNQDMCVKVPDDpeHLAARRQWRDECLMRLAKLKS 260
Cdd:PRK06129 244 VADYAQRYGPMYRRMAAERGQPVPWDGELVARVEAERRAALPLD--QLAARQAWRDRRLMALAAHRR 308
FadB COG1250
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ...
 9-189 1.27e-48

3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440862 [Multi-domain]  Cd Length: 281  Bit Score: 162.20  E-value: 1.27e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGALKGSlSAEEQLSLISGCPN-------- 80
Cdd:COG1250    5 VAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEE-EADAALARITPTTDlaaladad 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  81 -IQEAV-------------------EGA--------------------------MHIqVNPPYYIPLVELVPHPETAPTT 114
Cdd:COG1250   84 lVIEAVpedldlkqevfaeldavapPDAilasntsslsitelaaatkrperfigLHF-FNPVPLMPLVEVIRGPATSDET 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 967261784 115 VDRTHALMKKIGQCPMRVqKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRyafIGPLETMHL 189
Cdd:COG1250  163 VATAVAFARRLGKTPVVV-KDTPGFIVNRILVPYLNEAIRLLEEGVASPEDIDAAMRLGFGFP---MGPFELADL 233
PRK06130 PRK06130
3-hydroxybutyryl-CoA dehydrogenase; Validated
 11-190 3.19e-36

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 235707 [Multi-domain]  Cd Length: 311  Bit Score: 130.66  E-value: 3.19e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  11 IVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENI-RKEMKL--LEQAGALKGSLSAE------------------ 69
Cdd:PRK06130   9 IIGAGTMGSGIAALFARKGLQVVLIDVMEGALERARGVIeRALGVYapLGIASAGMGRIRMEaglaaavsgadlvieavp 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  70 EQLSL---------------------ISGCP--NIQEAVEG-----AMHIqVNPPYYIPLVELVPHPETAPTTVDRTHAL 121
Cdd:PRK06130  89 EKLELkrdvfarldglcdpdtifatnTSGLPitAIAQAVTRperfvGTHF-FTPADVIPLVEVVRGDKTSPQTVATTMAL 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 967261784 122 MKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLN 190
Cdd:PRK06130 168 LRSIGKRPVLVKKDIPGFIANRIQHALAREAISLLEKGVASAEDIDEVVKWSLGIRLALTGPLEQRDMN 236
3HCDH_N pfam02737
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ...
 9-132 3.45e-29

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.


Pssm-ID: 397037 [Multi-domain]  Cd Length: 180  Bit Score: 108.78  E-value: 3.45e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784    9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGALKGSlSAEEQLSLISGCPNIQEAVE-- 86
Cdd:pfam02737   2 VAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERLVEKGRITEE-EVDAALARISFTTDLAAAVDad 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   87 ----------------------------------------------------GAMHIqVNPPYYIPLVELVPHPETAPTT 114
Cdd:pfam02737  81 lvieavpenlelkrklfaeldaiappdailatntsslsitelaaatkrperfIGLHF-FNPPPLMPLVEVVRGEKTSPET 159

                         170
                  ....*....|....*...
gi 967261784  115 VDRTHALMKKIGQCPMRV 132
Cdd:pfam02737 160 VATTVELAKKIGKTPVVV 177
PRK07531 PRK07531
carnitine 3-dehydrogenase;
11-226 1.06e-27

carnitine 3-dehydrogenase;


Pssm-ID: 236044 [Multi-domain]  Cd Length: 495  Bit Score: 110.60  E-value: 1.06e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  11 IVGSGVIGRSWAMLFASGGFQVKLYDIE---QQQIRNALENIRKEMKLLEQAgalkgSLSAEEQLSLisgCPNIQEAVEG 87
Cdd:PRK07531   9 CIGGGVIGGGWAARFLLAGIDVAVFDPHpeaERIIGEVLANAERAYAMLTDA-----PLPPEGRLTF---CASLAEAVAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  88 AMHIQ------------------------------------------------------VNPPYYIPLVELVPHPETAPT 113
Cdd:PRK07531  81 ADWIQesvperldlkrrvlaeidaaarpdaligsstsgflpsdlqegmthperlfvahpYNPVYLLPLVELVGGGKTSPE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784 114 TVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLnAEG 193
Cdd:PRK07531 161 TIRRAKEILREIGMKPVHIAKEIDAFVGDRLLEALWREALWLVKDGIATTEEIDDVIRYSFGLRWAQMGLFETYRI-AGG 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 967261784 194 mlsycdrySEGMKHVLKTFGP-----------IPEFSRATAEKV 226
Cdd:PRK07531 240 --------EAGMRHFLAQFGPclkwpwtklmdVPDLDDALVDKI 275
PRK07066 PRK07066
L-carnitine dehydrogenase;
12-253 5.30e-23

L-carnitine dehydrogenase;


Pssm-ID: 168796 [Multi-domain]  Cd Length: 321  Bit Score: 95.67  E-value: 5.30e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  12 VGSGVIGRSWAMLFASGGFQVKLYDIE---QQQIRNALENirkEMKLLEQAGALKGSL---------------------- 66
Cdd:PRK07066  13 IGSGVIGSGWVARALAHGLDVVAWDPApgaEAALRANVAN---AWPALERQGLAPGASparlrfvatieacvadadfiqe 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  67 SAEEQLSL-------ISGC--PNI-----------QEAVEGAMHIQ-------VNPPYYIPLVELVPHPETAPTTVDRTH 119
Cdd:PRK07066  90 SAPEREALklelherISRAakPDAiiasstsgllpTDFYARATHPErcvvghpFNPVYLLPLVEVLGGERTAPEAVDAAM 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784 120 ALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLnAEGmlsycd 199
Cdd:PRK07066 170 GIYRALGMRPLHVRKEVPGFIADRLLEALWREALHLVNEGVATTGEIDDAIRFGAGIRWSFMGTFLTYTL-AGG------ 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 967261784 200 rySEGMKHVLKTFGPIPE--FSRATAEKVNQDMCVKVPD------DPEHLAARRQWRDECLM 253
Cdd:PRK07066 243 --DAGMRHFMQQFGPALElpWTKLVAPELTDALIDRVVEgtaeqqGPRSIKALERYRDECIT 302
PRK08269 PRK08269
3-hydroxybutyryl-CoA dehydrogenase; Validated
 94-204 2.47e-20

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181340 [Multi-domain]  Cd Length: 314  Bit Score: 88.19  E-value: 2.47e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  94 NPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMrVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEG 173
Cdd:PRK08269 140 NPAYLMPLVEVSPSDATDPAVVDRLAALLERIGKVPV-VCGPSPGYIVPRIQALAMNEAARMVEEGVASAEDIDKAIRTG 218

                         90       100       110
                 ....*....|....*....|....*....|.
gi 967261784 174 LGMRYAFIGPLETMHLNAEGMLSYCDRYSEG 204
Cdd:PRK08269 219 FGLRFAVLGLLEFIDWGGCDILYYASRYLAG 249
PRK08268 PRK08268
3-hydroxy-acyl-CoA dehydrogenase; Validated
 8-189 6.77e-20

3-hydroxy-acyl-CoA dehydrogenase; Validated


Pssm-ID: 236211 [Multi-domain]  Cd Length: 507  Bit Score: 88.37  E-value: 6.77e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   8 CVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEM-KLLE-------QAGALKGSLSAEEQLSLISGCP 79
Cdd:PRK08268   9 TVAVIGAGAMGAGIAQVAAQAGHTVLLYDARAGAAAAARDGIAARLaKLVEkgkltaeQADAALARLRPVEALADLADCD 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  80 NIQEA-VE----------------------------------GA----------MHIqVNPPYYIPLVELVPHPETAPTT 114
Cdd:PRK08268  89 LVVEAiVErldvkqalfaqleaivspdcilatntsslsitaiAAalkhpervagLHF-FNPVPLMKLVEVVSGLATDPAV 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 967261784 115 VDRTHALMKKIGQCPMRVqKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRyafIGPLETMHL 189
Cdd:PRK08268 168 ADALYALARAWGKTPVRA-KDTPGFIVNRAARPYYTEALRVLEEGVADPATIDAILREAAGFR---MGPFELMDL 238
3HCDH pfam00725
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ...
 138-226 4.13e-19

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.


Pssm-ID: 395588 [Multi-domain]  Cd Length: 97  Bit Score: 79.57  E-value: 4.13e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  138 GFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNAE--GMLSYCDRYSEGMKH---VLKTF 212
Cdd:pfam00725   1 GFVVNRLLAPYLNEAIRLVEEGVATPEDIDAAMRLGLGLPMGPFELSDLVGLDVGyhILEVLAEEFGDRAYRpppLLEKL 80

                          90
                  ....*....|....
gi 967261784  213 GPIPEFSRATAEKV 226
Cdd:pfam00725  81 VEAGRLGRKTGKGF 94
PRK09260 PRK09260
3-hydroxyacyl-CoA dehydrogenase;
9-185 1.39e-16

3-hydroxyacyl-CoA dehydrogenase;


Pssm-ID: 236434 [Multi-domain]  Cd Length: 288  Bit Score: 77.52  E-value: 1.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQirnaLENIRKEMKLLEQAGALKGSLSAEEQLSLISGCP---NIQEAV 85
Cdd:PRK09260   4 LVVVGAGVMGRGIAYVFAVSGFQTTLVDIKQEQ----LESAQQEIASIFEQGVARGKLTEAARQAALARLSyslDLKAAV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  86 EGA-------------------------------------------------------MHIqVNPPYYIPLVELVPHPET 110
Cdd:PRK09260  80 ADAdlvieavpeklelkkavfetadahapaecyiatntstmspteiasftkrperviaMHF-FNPVHKMKLVELIRGLET 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 967261784 111 APTTVDRTHALMKKIGQCPMRVQkEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSegLGMRYAfIGPLE 185
Cdd:PRK09260 159 SDETVQVAKEVAEQMGKETVVVN-EFPGFVTSRISALVGNEAFYMLQEGVATAEDIDKAIR--LGLNFP-MGPLE 229
PRK05808 PRK05808
3-hydroxybutyryl-CoA dehydrogenase; Validated
 9-184 2.06e-16

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 180269 [Multi-domain]  Cd Length: 282  Bit Score: 76.93  E-value: 2.06e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQagalKGSLSAEEQ---LSLISGCPNIQEA- 84
Cdd:PRK05808   6 IGVIGAGTMGNGIAQVCAVAGYDVVMVDISDAAVDRGLATITKSLDRLVK----KGKMTEADKeaaLARITGTTDLDDLk 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  85 -----VEGA------------------------------------------------MHIqVNPPYYIPLVELVPHPETA 111
Cdd:PRK05808  82 dadlvIEAAtenmdlkkkifaqldeiakpeailatntsslsitelaaatkrpdkvigMHF-FNPVPVMKLVEIIRGLATS 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 967261784 112 PTTVDRTHALMKKIGQCPMRVqKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSegLGMRYAfIGPL 184
Cdd:PRK05808 161 DATHEAVEALAKKIGKTPVEV-KNAPGFVVNRILIPMINEAIFVLAEGVATAEDIDEGMK--LGCNHP-IGPL 229
PRK08293 PRK08293
3-hydroxyacyl-CoA dehydrogenase;
9-187 3.26e-15

3-hydroxyacyl-CoA dehydrogenase;


Pssm-ID: 181359 [Multi-domain]  Cd Length: 287  Bit Score: 73.44  E-value: 3.26e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGALKGSLSAEEQLSLISGCPNIQEAVEGA 88
Cdd:PRK08293   6 VTVAGAGVLGSQIAFQTAFHGFDVTIYDISDEALEKAKERIAKLADRYVRDLEATKEAPAEAALNRITLTTDLAEAVKDA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  89 ----------MHI---------QVNPPYYI-----------------------------------PLVELVPHPETAPTT 114
Cdd:PRK08293  86 dlvieavpedPEIkgdfyeelaKVAPEKTIfatnsstllpsqfaeatgrpekflalhfaneiwknNTAEIMGHPGTDPEV 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 967261784 115 VDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRyafIGPLETM 187
Cdd:PRK08293 166 FDTVVAFAKAIGMVPIVLKKEQPGYILNSLLVPFLSAALALWAKGVADPETIDKTWMIATGAP---MGPFGIL 235
PLN02545 PLN02545
3-hydroxybutyryl-CoA dehydrogenase
 1-185 4.84e-14

3-hydroxybutyryl-CoA dehydrogenase


Pssm-ID: 215300 [Multi-domain]  Cd Length: 295  Bit Score: 70.53  E-value: 4.84e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   1 MASSAAgcVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLeqagALKGSLS---AEEQLSLISG 77
Cdd:PLN02545   1 MAEIKK--VGVVGAGQMGSGIAQLAAAAGMDVWLLDSDPAALSRGLDSISSSLARL----VKKGKMSqeeADATLGRIRC 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  78 CPNIQ---------EAV---EGA------------------------------------------MHIqVNPPYYIPLVE 103
Cdd:PLN02545  75 TTNLEelrdadfiiEAIvesEDLkkklfseldrickpsailasntssisitrlasatqrpqqvigMHF-MNPPPIMKLVE 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784 104 LVPHPETAPTTVDRTHALMKKIGQCPMRVQkEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRyafIGP 183
Cdd:PLN02545 154 IIRGADTSDEVFDATKALAERFGKTVVCSQ-DYPGFIVNRILMPMINEAFYALYTGVASKEDIDTGMKLGTNHP---MGP 229


                 ..
gi 967261784 184 LE 185
Cdd:PLN02545 230 LH 231
PRK06035 PRK06035
3-hydroxyacyl-CoA dehydrogenase; Validated
 11-189 1.62e-10

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 180361 [Multi-domain]  Cd Length: 291  Bit Score: 60.27  E-value: 1.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  11 IVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKE----MKLLE-------QAGALKGSLSAEEQLSLISGCP 79
Cdd:PRK06035   8 VVGSGVMGQGIAQVFARTGYDVTIVDVSEEILKNAMELIESGpyglRNLVEkgkmsedEAKAIMARIRTSTSYESLSDAD 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  80 NIQEAVEGAMHIQ--------------------------------------------VNPPYYIPLVELVPHPETAPTTV 115
Cdd:PRK06035  88 FIVEAVPEKLDLKrkvfaelernvspetiiasntsgimiaeiatalerkdrfigmhwFNPAPVMKLIEVVRAALTSEETF 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 967261784 116 DRTHALMKKIGQCPMRVqKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDlVMSEglgMRYAF-IGPLETMHL 189
Cdd:PRK06035 168 NTTVELSKKIGKIPIEV-ADVPGFFTTRFIEGWLLEAIRSFEIGIATIKDID-EMCK---LAFGFpMGPFELMDI 237
PRK07530 PRK07530
3-hydroxybutyryl-CoA dehydrogenase; Validated
 9-185 8.88e-08

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181018 [Multi-domain]  Cd Length: 292  Bit Score: 51.93  E-value: 8.88e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784   9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKllEQAGalKGSLSAEEQ---LSLISGCPNIQE-- 83
Cdd:PRK07530   7 VGVIGAGQMGNGIAHVCALAGYDVLLNDVSADRLEAGLATINGNLA--RQVA--KGKISEEARaaaLARISTATDLEDla 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  84 ----AVEGA------------------------------------------------MHIqVNPPYYIPLVELVPHPETA 111
Cdd:PRK07530  83 dcdlVIEAAtedetvkrkifaqlcpvlkpeailatntssisitrlasatdrperfigIHF-MNPVPVMKLVELIRGIATD 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 967261784 112 PTTVDRTHALMKKIGQCPMrVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSegLGMRYAfIGPLE 185
Cdd:PRK07530 162 EATFEAAKEFVTKLGKTIT-VAEDFPAFIVNRILLPMINEAIYTLYEGVGSVEAIDTAMK--LGANHP-MGPLE 231
PRK07819 PRK07819
3-hydroxybutyryl-CoA dehydrogenase; Validated
 94-194 1.17e-07

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181133 [Multi-domain]  Cd Length: 286  Bit Score: 51.53  E-value: 1.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784  94 NPPYYIPLVELVPHPETAPTTVDRTHALMKKI-GQCPMRVQKEvAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSE 172
Cdd:PRK07819 146 NPVPVLPLVELVPTLVTSEATVARAEEFASDVlGKQVVRAQDR-SGFVVNALLVPYLLSAIRMVESGFATAEDIDKAMVL 224

                         90       100
                 ....*....|....*....|....*...
gi 967261784 173 GLG-----MRYA-FIGpLETMHLNAEGM 194
Cdd:PRK07819 225 GCAhpmgpLRLSdLVG-LDTVKAIADSM 251
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
100-159 3.08e-07

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 51.05  E-value: 3.08e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784 100 PLVELVPHPETAPTTVDRTHALMKKIGQCPMrVQKEVAGFVLNRLQYAIISEAWRLVEEG 159
Cdd:PRK11154 456 PLVEVIPHAKTSAETIATTVALAKKQGKTPI-VVRDGAGFYVNRILAPYINEAARLLLEG 514
PRK08268 PRK08268
3-hydroxy-acyl-CoA dehydrogenase; Validated
 100-185 1.93e-05

3-hydroxy-acyl-CoA dehydrogenase; Validated


Pssm-ID: 236211 [Multi-domain]  Cd Length: 507  Bit Score: 45.22  E-value: 1.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967261784 100 PLVELVPHPETAPTTVDRTHALMKKIGQcPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGmrYA 179
Cdd:PRK08268 379 KRRTLMAAPATSPAARDAAHALFQQDGK-AVSVIRDSPGFVAQRTVAMIVNEAADIAQQGIASPADIDLAMRLGLN--YP 455


                 ....*.
gi 967261784 180 FiGPLE 185
Cdd:PRK08268 456 L-GPLA 460
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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