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Conserved domains on  [gi|967075571|ref|XP_014974819|]
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solute carrier family 35 member B1 isoform X1 [Macaca mulatta]

Protein Classification

nucleotide-sugar transporter family protein( domain architecture ID 706892)

nucleotide-sugar transporter family protein may mediate the transport of nucleotides or sugars or their derivatives; belongs to the drug/metabolite transporter (DMT) superfamily

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
UAA super family cl26745
UAA transporter family; This family includes transporters with a specificity for ...
53-346 5.65e-45

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


The actual alignment was detected with superfamily member pfam08449:

Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 156.30  E-value: 5.65e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571   53 LCFLGVFVCYFYYGILQEKItrgkygegAKQETFTFALTLVFIQCVINAVFAKILIQFFDTARVDRTRS---WLYAACSI 129
Cdd:pfam08449   4 LAVSGVFGGCCSNGVLQELI--------MKVEPGPFGNLLTFAQFLFYALEGLPESIDIFTSKFLKPRKiplKTYVILVA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  130 SYLGAMVSSNSALQF-VNYPTQVLGKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKKVVGiEEHTVGY 208
Cdd:pfam08449  76 LFFITSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLFSAKDKV-ADSVVSP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  209 -----GELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLgmgILFTGEL---WEFLSFAERY-----PA 275
Cdd:pfam08449 155 nffliGIAMLSGALLLDAFLGNYQEKTYKKYGKHSKEMLFYSHLLSLPFF---LLLQGDLfsaVQFCSQSPDKavlslPS 231
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 967075571  276 IIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPVQWVGTVLVFLGLGL 346
Cdd:pfam08449 232 MLFYLLLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFL 302
 
Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
53-346 5.65e-45

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 156.30  E-value: 5.65e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571   53 LCFLGVFVCYFYYGILQEKItrgkygegAKQETFTFALTLVFIQCVINAVFAKILIQFFDTARVDRTRS---WLYAACSI 129
Cdd:pfam08449   4 LAVSGVFGGCCSNGVLQELI--------MKVEPGPFGNLLTFAQFLFYALEGLPESIDIFTSKFLKPRKiplKTYVILVA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  130 SYLGAMVSSNSALQF-VNYPTQVLGKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKKVVGiEEHTVGY 208
Cdd:pfam08449  76 LFFITSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLFSAKDKV-ADSVVSP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  209 -----GELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLgmgILFTGEL---WEFLSFAERY-----PA 275
Cdd:pfam08449 155 nffliGIAMLSGALLLDAFLGNYQEKTYKKYGKHSKEMLFYSHLLSLPFF---LLLQGDLfsaVQFCSQSPDKavlslPS 231
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 967075571  276 IIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPVQWVGTVLVFLGLGL 346
Cdd:pfam08449 232 MLFYLLLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFL 302
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
89-346 7.56e-07

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 50.23  E-value: 7.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  89 ALTLVFIQCVINAVF--AKILIQFFDTARVDRTRSWLYAACSI-SYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLG 165
Cdd:COG0697   31 PLQLAFLRFLLAALLllPLLLLRGRRLPPLSRRDWLLLLLRGLlGLALAFLLFFLALQYTPAALAALLLALAPLFVALLA 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571 166 VTLLKKKYPLAKYLCVLLIVAGVALFMYKPkkvvGIEEHTVGYGELLLLLSLTLDGLTGVSQDHMRAHYqtGSNHMMLNI 245
Cdd:COG0697  111 ALLLGERLSRRRWLGLLLGFAGVLLIVGPG----GGGGGGSLLGDLLALLAALSWALYTVLTRRLSRRL--DPLTLTFWQ 184
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571 246 NLWSTLLLGMGILFTGELWEFLSFAerYPAIIYNILLfglTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILF 325
Cdd:COG0697  185 MLVGALLLLPLALLTGLPLPLSAAA--WLALLYLGLF---GTALAYLLWFRALRRLGASRAAPLTYLEPVFAVLLGWLLL 259
                        250       260
                 ....*....|....*....|.
gi 967075571 326 ANPISPVQWVGTVLVFLGLGL 346
Cdd:COG0697  260 GEPLTPLQLLGAALILAGVLL 280
nst TIGR00803
UDP-galactose transporter; The 10-12 TMS Nucleotide Sugar Transporters (TC 2.A.7.10) ...
242-346 7.75e-05

UDP-galactose transporter; The 10-12 TMS Nucleotide Sugar Transporters (TC 2.A.7.10)Nucleotide-sugar transporters (NSTs) are found in the Golgi apparatus and the endoplasmic reticulum of eukaryotic cells. Members of the family have been sequenced from yeast, protozoans and animals. Animals such as C. elegans possess many of these transporters. Humans have at least two closely related isoforms of the UDP-galactose:UMP exchange transporter.NSTs generally appear to function by antiport mechanisms, exchanging a nucleotide-sugar for a nucleotide. Thus, CMP-sialic acid is exchanged for CMP; GDP-mannose is preferentially exchanged for GMP, and UDP-galactose and UDP-N-acetylglucosamine are exchanged for UMP (or possibly UDP). Other nucleotide sugars (e.g., GDP-fucose, UDP-xylose, UDP-glucose, UDP-N-acetylgalactosamine, etc.) may also be transported in exchange for various nucleotides, but their transporters have not been molecularly characterized. Each compound appears to be translocated by its own transport protein. Transport allows the compound, synthesized in the cytoplasm, to be exported to the lumen of the Golgi apparatus or the endoplasmic reticulum where it is used for the synthesis of glycoproteins and glycolipids.


Pssm-ID: 129885  Cd Length: 222  Bit Score: 43.50  E-value: 7.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  242 MLNINLWSTLLLGMGILFTGELWE------FLSFAERYPAIIYnilLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKF 315
Cdd:TIGR00803 114 MFWSRNLQLPLFGLFSTFSVLLWSdgtlisNFGFFIGYPTAVW---IVGLLNVGGGLCIGGVVRYADNTTKSFVTALSII 190
                          90       100       110
                  ....*....|....*....|....*....|.
gi 967075571  316 FTILASVILFANPISPVQWVGTVLVFLGLGL 346
Cdd:TIGR00803 191 LSTLASVRLFDAKISSTFYLGAILVFLATFL 221
PTZ00343 PTZ00343
triose or hexose phosphate/phosphate translocator; Provisional
131-343 3.65e-03

triose or hexose phosphate/phosphate translocator; Provisional


Pssm-ID: 240371 [Multi-domain]  Cd Length: 350  Bit Score: 38.95  E-value: 3.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571 131 YLGAMVS-SNSALQFvnypTQVLgKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALfmykpKKVVGIEEHTVGYG 209
Cdd:PTZ00343 128 HFGAVISmGLGAVSF----THVV-KAAEPVFTALLSILFLKQFLNLYAYLSLIPIVGGVAL-----ASVKELHFTWLAFW 197
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571 210 eLLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLGMG---ILFTGELWEFLSFAERYPA---------II 277
Cdd:PTZ00343 198 -CAMLSNLGSSLRSIFAKKTMKNKSEIGENLTASNIYMLLTLIASLIslpLVLFFEGKKWVPVWTNYTAnmtnytkgiII 276
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 967075571 278 YNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPVQWVGTVLVFLG 343
Cdd:PTZ00343 277 FKIFFSGVWYYLYNEVAFYCLGKVNQVTHAVANTLKRVVIIVSSIIIFQTQVTLLGYLGMAVAILG 342
 
Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
53-346 5.65e-45

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 156.30  E-value: 5.65e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571   53 LCFLGVFVCYFYYGILQEKItrgkygegAKQETFTFALTLVFIQCVINAVFAKILIQFFDTARVDRTRS---WLYAACSI 129
Cdd:pfam08449   4 LAVSGVFGGCCSNGVLQELI--------MKVEPGPFGNLLTFAQFLFYALEGLPESIDIFTSKFLKPRKiplKTYVILVA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  130 SYLGAMVSSNSALQF-VNYPTQVLGKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKKVVGiEEHTVGY 208
Cdd:pfam08449  76 LFFITSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLFSAKDKV-ADSVVSP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  209 -----GELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLgmgILFTGEL---WEFLSFAERY-----PA 275
Cdd:pfam08449 155 nffliGIAMLSGALLLDAFLGNYQEKTYKKYGKHSKEMLFYSHLLSLPFF---LLLQGDLfsaVQFCSQSPDKavlslPS 231
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 967075571  276 IIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPVQWVGTVLVFLGLGL 346
Cdd:pfam08449 232 MLFYLLLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFL 302
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
89-346 7.56e-07

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 50.23  E-value: 7.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  89 ALTLVFIQCVINAVF--AKILIQFFDTARVDRTRSWLYAACSI-SYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLG 165
Cdd:COG0697   31 PLQLAFLRFLLAALLllPLLLLRGRRLPPLSRRDWLLLLLRGLlGLALAFLLFFLALQYTPAALAALLLALAPLFVALLA 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571 166 VTLLKKKYPLAKYLCVLLIVAGVALFMYKPkkvvGIEEHTVGYGELLLLLSLTLDGLTGVSQDHMRAHYqtGSNHMMLNI 245
Cdd:COG0697  111 ALLLGERLSRRRWLGLLLGFAGVLLIVGPG----GGGGGGSLLGDLLALLAALSWALYTVLTRRLSRRL--DPLTLTFWQ 184
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571 246 NLWSTLLLGMGILFTGELWEFLSFAerYPAIIYNILLfglTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILF 325
Cdd:COG0697  185 MLVGALLLLPLALLTGLPLPLSAAA--WLALLYLGLF---GTALAYLLWFRALRRLGASRAAPLTYLEPVFAVLLGWLLL 259
                        250       260
                 ....*....|....*....|.
gi 967075571 326 ANPISPVQWVGTVLVFLGLGL 346
Cdd:COG0697  260 GEPLTPLQLLGAALILAGVLL 280
TPT pfam03151
Triose-phosphate Transporter family; This family includes transporters with a specificity for ...
154-343 1.09e-06

Triose-phosphate Transporter family; This family includes transporters with a specificity for triose phosphate.


Pssm-ID: 308657 [Multi-domain]  Cd Length: 290  Bit Score: 49.60  E-value: 1.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  154 KSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKpkkvvgiEEHTVGYGELLLLLSLTLDGLTGV-------- 225
Cdd:pfam03151  98 KAMEPFFTVILSRLFLGEYPPLLVYLSLLPIVGGVALASVT-------ELSFNWIGFISAMISNLGFSLRNIfskklmkg 170
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  226 --SQDHMRAHYQTGSNHMMLNINLWstlLLGMGILFTGELWEFLSFAerYPAIIYNILLFGLTSALGQSFIFMTVVYFGP 303
Cdd:pfam03151 171 kdNLDNLNLFAIITILSLLLLLPVW---LLVEGFKKFPSLLQSGKVG--LKDVYMLLLLSGVCFHLYNQVAYMILERVSP 245
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 967075571  304 LTCSIITTTRKFFTILASVILFANPISPVQWVGTVLVFLG 343
Cdd:pfam03151 246 VTHSVANTVKRVVVIVSSILVFGNPVSPLNAIGTAIAIAG 285
nst TIGR00803
UDP-galactose transporter; The 10-12 TMS Nucleotide Sugar Transporters (TC 2.A.7.10) ...
242-346 7.75e-05

UDP-galactose transporter; The 10-12 TMS Nucleotide Sugar Transporters (TC 2.A.7.10)Nucleotide-sugar transporters (NSTs) are found in the Golgi apparatus and the endoplasmic reticulum of eukaryotic cells. Members of the family have been sequenced from yeast, protozoans and animals. Animals such as C. elegans possess many of these transporters. Humans have at least two closely related isoforms of the UDP-galactose:UMP exchange transporter.NSTs generally appear to function by antiport mechanisms, exchanging a nucleotide-sugar for a nucleotide. Thus, CMP-sialic acid is exchanged for CMP; GDP-mannose is preferentially exchanged for GMP, and UDP-galactose and UDP-N-acetylglucosamine are exchanged for UMP (or possibly UDP). Other nucleotide sugars (e.g., GDP-fucose, UDP-xylose, UDP-glucose, UDP-N-acetylgalactosamine, etc.) may also be transported in exchange for various nucleotides, but their transporters have not been molecularly characterized. Each compound appears to be translocated by its own transport protein. Transport allows the compound, synthesized in the cytoplasm, to be exported to the lumen of the Golgi apparatus or the endoplasmic reticulum where it is used for the synthesis of glycoproteins and glycolipids.


Pssm-ID: 129885  Cd Length: 222  Bit Score: 43.50  E-value: 7.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  242 MLNINLWSTLLLGMGILFTGELWE------FLSFAERYPAIIYnilLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKF 315
Cdd:TIGR00803 114 MFWSRNLQLPLFGLFSTFSVLLWSdgtlisNFGFFIGYPTAVW---IVGLLNVGGGLCIGGVVRYADNTTKSFVTALSII 190
                          90       100       110
                  ....*....|....*....|....*....|.
gi 967075571  316 FTILASVILFANPISPVQWVGTVLVFLGLGL 346
Cdd:TIGR00803 191 LSTLASVRLFDAKISSTFYLGAILVFLATFL 221
tpt TIGR00817
Tpt phosphate/phosphoenolpyruvate translocator; The 6-8 TMS Triose-phosphate Transporter (TPT) ...
291-356 7.55e-04

Tpt phosphate/phosphoenolpyruvate translocator; The 6-8 TMS Triose-phosphate Transporter (TPT) Family (TC 2.A.7.9)Functionally characterized members of the TPT family are derived from the inner envelope membranes of chloroplasts and nongreen plastids of plants. However,homologues are also present in yeast. Saccharomyces cerevisiae has three functionally uncharacterized TPT paralogues encoded within its genome. Under normal physiologicalconditions, chloroplast TPTs mediate a strict antiport of substrates, frequently exchanging an organic three carbon compound phosphate ester for inorganic phosphate (Pi).Normally, a triose-phosphate, 3-phosphoglycerate, or another phosphorylated C3 compound made in the chloroplast during photosynthesis, exits the organelle into thecytoplasm of the plant cell in exchange for Pi. However, experiments with reconstituted translocator in artificial membranes indicate that transport can also occur by achannel-like uniport mechanism with up to 10-fold higher transport rates. Channel opening may be induced by a membrane potential of large magnitude and/or by high substrateconcentrations. Nongreen plastid and chloroplast carriers, such as those from maize endosperm and root membranes, mediate transport of C3 compounds phosphorylated atcarbon atom 2, particularly phosphenolpyruvate, in exchange for Pi. These are the phosphoenolpyruvate:Pi antiporters (PPT). Glucose-6-P has also been shown to be asubstrate of some plastid translocators (GPT). The three types of proteins (TPT, PPT and GPT) are divergent in sequence as well as substrate specificity, but their substratespecificities overlap. [Hypothetical proteins, Conserved]


Pssm-ID: 129898 [Multi-domain]  Cd Length: 302  Bit Score: 40.86  E-value: 7.55e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 967075571  291 QSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPVQWVGTVLVFLGLGLDAKFGKGAKK 356
Cdd:TIGR00817 235 QQVAFMLLGRVSPLTHSVGNCMKRVVVIVVSILFFGTKISPQQVFGTGIAIAGVFLYSRVKAQKPK 300
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
245-346 2.72e-03

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 37.56  E-value: 2.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571  245 INLWSTLLLGMGILFTGELWEFlSFAERYPAIIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVIL 324
Cdd:pfam00892  33 LTFWRFLIAGILLLPFALFTGG-KLVIPLKSWLALLYLGVLGTFLGFLLYFYGLKYVSASNASVITSLSPVFTLILSVLL 111
                          90       100
                  ....*....|....*....|..
gi 967075571  325 FANPISPVQWVGTVLVFLGLGL 346
Cdd:pfam00892 112 LGEKLTLKQLLGIVLILLGVLL 133
PTZ00343 PTZ00343
triose or hexose phosphate/phosphate translocator; Provisional
131-343 3.65e-03

triose or hexose phosphate/phosphate translocator; Provisional


Pssm-ID: 240371 [Multi-domain]  Cd Length: 350  Bit Score: 38.95  E-value: 3.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571 131 YLGAMVS-SNSALQFvnypTQVLgKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALfmykpKKVVGIEEHTVGYG 209
Cdd:PTZ00343 128 HFGAVISmGLGAVSF----THVV-KAAEPVFTALLSILFLKQFLNLYAYLSLIPIVGGVAL-----ASVKELHFTWLAFW 197
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967075571 210 eLLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLGMG---ILFTGELWEFLSFAERYPA---------II 277
Cdd:PTZ00343 198 -CAMLSNLGSSLRSIFAKKTMKNKSEIGENLTASNIYMLLTLIASLIslpLVLFFEGKKWVPVWTNYTAnmtnytkgiII 276
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 967075571 278 YNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPVQWVGTVLVFLG 343
Cdd:PTZ00343 277 FKIFFSGVWYYLYNEVAFYCLGKVNQVTHAVANTLKRVVIIVSSIIIFQTQVTLLGYLGMAVAILG 342
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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