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Conserved domains on  [gi|1622873603|ref|XP_014972750|]
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extracellular matrix protein 2 isoform X1 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
317-674 2.57e-27

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 115.03  E-value: 2.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 317 LPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNitspgigpkAFKLLKKL 396
Cdd:COG4886    45 LLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNL 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 397 TRLNMDGNNLIQIPSELPS--TLEELKINENNLQAIDkESLSDLYQLVTLELEGNNLSEVnvnPLAFKPLKSLAYLRLGK 474
Cdd:COG4886   116 ESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLP-EPLGNLTNLKSLDLSNNQLTDL---PEELGNLTNLKELDLSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 475 NKFRIIPQGL--PASIEELYLENNQIEEITEicfnhtrkinvivlrynkieenriaPLAwiNQENLESIDLSYNKLYHVP 552
Cdd:COG4886   192 NQITDLPEPLgnLTNLEELDLSGNQLTDLPE-------------------------PLA--NLTNLETLDLSNNQLTDLP 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 553 --SYLPKsLLHLVLLGNQIERIPgyVFGHMePGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKSVPPGIQE 630
Cdd:COG4886   245 elGNLTN-LEELDLSNNQLTDLP--PLANL-TNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLL 320

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1622873603 631 MKALHFLRLNNNKIRNILPEEICNAEEDDDSNLEHLHLENNYIK 674
Cdd:COG4886   321 TTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLT 364
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 103-157 7.69e-15

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


:

Pssm-ID: 278520  Cd Length: 57  Bit Score: 69.38  E-value: 7.69e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622873603 103 CLVKGITMYNKAVWSPEPCTTCLCSDGRVLCDETMCHPQRCPQT--VIPEGECCPVC 157
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
Amnionless super family cl28792
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ...
 116-217 7.07e-05

Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.


The actual alignment was detected with superfamily member pfam14828:

Pssm-ID: 464340  Cd Length: 449  Bit Score: 45.84  E-value: 7.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 116 WSPEPC---TTCLCSDGRVLcdETMCH--PQRCPQT-----VIPEGECCPVCSATVSysllsgiaLNDRNEFSGDSSEQR 185
Cdd:pfam14828 186 VGPEACsdpSGCGCGNDENL--ERICAnvLQRCPPPhclspLRPEGHCCDVCGAIVS--------LDYSSCFDLQTYRAR 255

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1622873603 186 eptnLLHKQLPPP-----QVGMDQIVRKEALQSEEDE 217
Cdd:pfam14828 256 ----LRHLFLALPkykgvQLAVSKVGKDQRLHISDNE 288
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
317-674 2.57e-27

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 115.03  E-value: 2.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 317 LPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNitspgigpkAFKLLKKL 396
Cdd:COG4886    45 LLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNL 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 397 TRLNMDGNNLIQIPSELPS--TLEELKINENNLQAIDkESLSDLYQLVTLELEGNNLSEVnvnPLAFKPLKSLAYLRLGK 474
Cdd:COG4886   116 ESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLP-EPLGNLTNLKSLDLSNNQLTDL---PEELGNLTNLKELDLSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 475 NKFRIIPQGL--PASIEELYLENNQIEEITEicfnhtrkinvivlrynkieenriaPLAwiNQENLESIDLSYNKLYHVP 552
Cdd:COG4886   192 NQITDLPEPLgnLTNLEELDLSGNQLTDLPE-------------------------PLA--NLTNLETLDLSNNQLTDLP 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 553 --SYLPKsLLHLVLLGNQIERIPgyVFGHMePGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKSVPPGIQE 630
Cdd:COG4886   245 elGNLTN-LEELDLSNNQLTDLP--PLANL-TNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLL 320

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1622873603 631 MKALHFLRLNNNKIRNILPEEICNAEEDDDSNLEHLHLENNYIK 674
Cdd:COG4886   321 TTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLT 364
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
321-573 1.70e-17

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 86.67  E-value: 1.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 321 CSLSYRTISCINAM-LTQIPPLTAPQITSLELTGNSIASIPDeafNGLPNLERLDLSKNNITS-PGIGPKAFKLLkkltr 398
Cdd:PRK15370  175 CLKNNKTELRLKILgLTTIPACIPEQITTLILDNNELKSLPE---NLQGNIKTLYANSNQLTSiPATLPDTIQEM----- 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 399 lNMDGNNLIQIPSELPSTLEELKINENNLQAIdKESLSDlyQLVTLELEGNNLS-----------EVNV--NPLAFKPLK 465
Cdd:PRK15370  247 -ELSINRITELPERLPSALQSLDLFHNKISCL-PENLPE--ELRYLSVYDNSIRtlpahlpsgitHLNVqsNSLTALPET 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 466 ---SLAYLRLGKNKFRIIPQGLPASIEELYLENNQIEEITEIcfnhtrkinvivlrynkieenrIAPlawinqeNLESID 542
Cdd:PRK15370  323 lppGLKTLEAGENALTSLPASLPPELQVLDVSKNQITVLPET----------------------LPP-------TITTLD 373

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1622873603 543 LSYNKLYHVPSYLPKSLLHLVLLGNQIERIP 573
Cdd:PRK15370  374 VSRNALTNLPENLPAALQIMQASRNNLVRLP 404
LRR_8 pfam13855
Leucine rich repeat;
344-406 4.19e-15

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 69.86  E-value: 4.19e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622873603 344 PQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSpgIGPKAFKLLKKLTRLNMDGNNL 406
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGNRL 61
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 103-157 7.69e-15

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 69.38  E-value: 7.69e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622873603 103 CLVKGITMYNKAVWSPEPCTTCLCSDGRVLCDETMCHPQRCPQT--VIPEGECCPVC 157
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
103-157 2.48e-12

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 62.15  E-value: 2.48e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622873603  103 CLVKGITMYNKAVWSPEPCTTCLCSDGR-VLCDETMCHP-QRCPQ--TVIPEGECCPVC 157
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTtVLCDPVECPPpPDCPNpeRVKPPGECCPRC 59
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 335-505 1.28e-09

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 58.64  E-value: 1.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 335 LTQIPPL-TAPQITSLELTGNSIASIpdEAFNGLPNLERLDLSKNNITSpgigpkafklLKKLTRLNMdgnnliqipsel 413
Cdd:cd21340    36 ITKIENLeFLTNLTHLYLQNNQIEKI--ENLENLVNLKKLYLGGNRISV----------VEGLENLTN------------ 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 414 pstLEELKINENNLQ-----AIDKESLSDL-YQLVTLELEGNNLSEvnvnplafkpLKSLAYLRlgknkfriipqglpaS 487
Cdd:cd21340    92 ---LEELHIENQRLPpgeklTFDPRSLAALsNSLRVLNISGNNIDS----------LEPLAPLR---------------N 143

                         170
                  ....*....|....*...
gi 1622873603 488 IEELYLENNQIEEITEIC 505
Cdd:cd21340   144 LEQLDASNNQISDLEELL 161
Amnionless pfam14828
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ...
 116-217 7.07e-05

Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.


Pssm-ID: 464340  Cd Length: 449  Bit Score: 45.84  E-value: 7.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 116 WSPEPC---TTCLCSDGRVLcdETMCH--PQRCPQT-----VIPEGECCPVCSATVSysllsgiaLNDRNEFSGDSSEQR 185
Cdd:pfam14828 186 VGPEACsdpSGCGCGNDENL--ERICAnvLQRCPPPhclspLRPEGHCCDVCGAIVS--------LDYSSCFDLQTYRAR 255

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1622873603 186 eptnLLHKQLPPP-----QVGMDQIVRKEALQSEEDE 217
Cdd:pfam14828 256 ----LRHLFLALPkykgvQLAVSKVGKDQRLHISDNE 288
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
317-674 2.57e-27

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 115.03  E-value: 2.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 317 LPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNitspgigpkAFKLLKKL 396
Cdd:COG4886    45 LLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNL 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 397 TRLNMDGNNLIQIPSELPS--TLEELKINENNLQAIDkESLSDLYQLVTLELEGNNLSEVnvnPLAFKPLKSLAYLRLGK 474
Cdd:COG4886   116 ESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLP-EPLGNLTNLKSLDLSNNQLTDL---PEELGNLTNLKELDLSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 475 NKFRIIPQGL--PASIEELYLENNQIEEITEicfnhtrkinvivlrynkieenriaPLAwiNQENLESIDLSYNKLYHVP 552
Cdd:COG4886   192 NQITDLPEPLgnLTNLEELDLSGNQLTDLPE-------------------------PLA--NLTNLETLDLSNNQLTDLP 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 553 --SYLPKsLLHLVLLGNQIERIPgyVFGHMePGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKSVPPGIQE 630
Cdd:COG4886   245 elGNLTN-LEELDLSNNQLTDLP--PLANL-TNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLL 320

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1622873603 631 MKALHFLRLNNNKIRNILPEEICNAEEDDDSNLEHLHLENNYIK 674
Cdd:COG4886   321 TTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLT 364
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
338-683 4.24e-24

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 105.40  E-value: 4.24e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 338 IPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSPGIGPKAFKLLKKLTRLNMDGNNLIQIPSELPSTL 417
Cdd:COG4886    13 LLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 418 EELKiNENNLQAIDKESLSDLYQLVTLELEGNNLSEVnvnPLAFKPLKSLAYLRLGKNKFRIIPQGLP--ASIEELYLEN 495
Cdd:COG4886    93 GDLT-NLTELDLSGNEELSNLTNLESLDLSGNQLTDL---PEELANLTNLKELDLSNNQLTDLPEPLGnlTNLKSLDLSN 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 496 NQIEEITEICFNHTrKINVIVLRYNKIEEnriAPLAWINQENLESIDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIP 573
Cdd:COG4886   169 NQLTDLPEELGNLT-NLKELDLSNNQITD---LPEPLGNLTNLEELDLSGNQLTDLPEPLAnlTNLETLDLSNNQLTDLP 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 574 GyvFGHMePGLEYLYLSFNKLADdgmdrVSFYGAYHSLRELFLDHNDLKSVppgiqEMKALHFLRLNNNKIRNILPEEIC 653
Cdd:COG4886   245 E--LGNL-TNLEELDLSNNQLTD-----LPPLANLTNLKTLDLSNNQLTDL-----KLKELELLLGLNSLLLLLLLLNLL 311

                         330       340       350
                  ....*....|....*....|....*....|
gi 1622873603 654 NAEEDDDSNLEHLHLENNYIKIREIPSYTF 683
Cdd:COG4886   312 ELLILLLLLTTLLLLLLLLKGLLVTLTTLA 341
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
369-680 1.50e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 91.53  E-value: 1.50e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 369 NLERLDLSKNNITSPGIGPKAFKLLKKLTRLNMDGNNLIQIPSELPSTLEELKINENNLQAIDKESLSDLYQLVTLeLEG 448
Cdd:COG4886     1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLL-LSL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 449 NNLSEVNVNPLAFKPLKSLAYLRLGKNKfriiPQGLPASIEELYLENNQIEEITEicfnhtrkinvivlrynkieenRIA 528
Cdd:COG4886    80 LLLSLLLLGLTDLGDLTNLTELDLSGNE----ELSNLTNLESLDLSGNQLTDLPE----------------------ELA 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 529 PLawinqENLESIDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGyVFGHMePGLEYLYLSFNKLADDGMdrvSFYG 606
Cdd:COG4886   134 NL-----TNLKELDLSNNQLTDLPEPLGnlTNLKSLDLSNNQLTDLPE-ELGNL-TNLKELDLSNNQITDLPE---PLGN 203

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622873603 607 AyHSLRELFLDHNDLKSVPPGIQEMKALHFLRLNNNKIRNIlpEEICNAeedddSNLEHLHLENNyiKIREIPS 680
Cdd:COG4886   204 L-TNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDL--PELGNL-----TNLEELDLSNN--QLTDLPP 267
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
335-546 1.51e-17

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 85.37  E-value: 1.51e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 335 LTQIPPLTA--PQITSLELTGNSIASIPDEaFNGLPNLERLDLSKNNITSPgigPKAFKLLKKLTRLNMDGNNLIQIP-- 410
Cdd:COG4886   171 LTDLPEELGnlTNLKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQLTDL---PEPLANLTNLETLDLSNNQLTDLPel 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 411 SELPStLEELKINENNLQAIDKesLSDLYQLVTLELEGNNLSEVNVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPASIEE 490
Cdd:COG4886   247 GNLTN-LEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTL 323

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622873603 491 LYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYN 546
Cdd:COG4886   324 LLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATL 379
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
321-573 1.70e-17

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 86.67  E-value: 1.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 321 CSLSYRTISCINAM-LTQIPPLTAPQITSLELTGNSIASIPDeafNGLPNLERLDLSKNNITS-PGIGPKAFKLLkkltr 398
Cdd:PRK15370  175 CLKNNKTELRLKILgLTTIPACIPEQITTLILDNNELKSLPE---NLQGNIKTLYANSNQLTSiPATLPDTIQEM----- 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 399 lNMDGNNLIQIPSELPSTLEELKINENNLQAIdKESLSDlyQLVTLELEGNNLS-----------EVNV--NPLAFKPLK 465
Cdd:PRK15370  247 -ELSINRITELPERLPSALQSLDLFHNKISCL-PENLPE--ELRYLSVYDNSIRtlpahlpsgitHLNVqsNSLTALPET 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 466 ---SLAYLRLGKNKFRIIPQGLPASIEELYLENNQIEEITEIcfnhtrkinvivlrynkieenrIAPlawinqeNLESID 542
Cdd:PRK15370  323 lppGLKTLEAGENALTSLPASLPPELQVLDVSKNQITVLPET----------------------LPP-------TITTLD 373

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1622873603 543 LSYNKLYHVPSYLPKSLLHLVLLGNQIERIP 573
Cdd:PRK15370  374 VSRNALTNLPENLPAALQIMQASRNNLVRLP 404
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
370-634 2.37e-15

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 80.13  E-value: 2.37e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 370 LERLDLSknniTSPGIGPKafkllkKLTRLNMDGNNLIQIPSELPSTLEELKINENNLQAIdKESLSDLYQLvtLELEGN 449
Cdd:PRK15370  185 LKILGLT----TIPACIPE------QITTLILDNNELKSLPENLQGNIKTLYANSNQLTSI-PATLPDTIQE--MELSIN 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 450 NLSEVNVN-PLAFKPL---------------KSLAYLRLGKNKFRIIPQGLPASIEELYLENNQIEEITEicfnhTRKIN 513
Cdd:PRK15370  252 RITELPERlPSALQSLdlfhnkisclpenlpEELRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPE-----TLPPG 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 514 VIVLrynKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPgyvfGHMEPGLEYLYLSFNK 593
Cdd:PRK15370  327 LKTL---EAGENALTSLPASLPPELQVLDVSKNQITVLPETLPPTITTLDVSRNALTNLP----ENLPAALQIMQASRNN 399

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1622873603 594 LADDGMDRVSFYGAYHSLRELFLDHNDLKSVPpgIQEMKAL 634
Cdd:PRK15370  400 LVRLPESLPHFRGEGPQPTRIIVEYNPFSERT--IQNMQRL 438
LRR_8 pfam13855
Leucine rich repeat;
344-406 4.19e-15

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 69.86  E-value: 4.19e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622873603 344 PQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSpgIGPKAFKLLKKLTRLNMDGNNL 406
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGNRL 61
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 103-157 7.69e-15

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 69.38  E-value: 7.69e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622873603 103 CLVKGITMYNKAVWSPEPCTTCLCSDGRVLCDETMCHPQRCPQT--VIPEGECCPVC 157
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
315-572 9.51e-15

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 78.20  E-value: 9.51e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 315 LRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEafngLPN-LERLDLSKNNITS-PGIGPkafkl 392
Cdd:PRK15370  212 KSLPENLQGNIKTLYANSNQLTSIPATLPDTIQEMELSINRITELPER----LPSaLQSLDLFHNKISClPENLP----- 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 393 lKKLTRLNMDGNNLIQIPSELPSTLEELKINENNLQAIdKESLSdlYQLVTLELEGNNLSEVnvnPLAFKPlkSLAYLRL 472
Cdd:PRK15370  283 -EELRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTAL-PETLP--PGLKTLEAGENALTSL---PASLPP--ELQVLDV 353

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 473 GKNKFRIIPQGLPASIEELYLENNQIEEITEicfnhtrkiNVivlrynkieenriaPLAwinqenLESIDLSYNKLyhvp 552
Cdd:PRK15370  354 SKNQITVLPETLPPTITTLDVSRNALTNLPE---------NL--------------PAA------LQIMQASRNNL---- 400

                         250       260
                  ....*....|....*....|
gi 1622873603 553 SYLPKSLLHLVLLGNQIERI 572
Cdd:PRK15370  401 VRLPESLPHFRGEGPQPTRI 420
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
335-550 4.04e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 71.89  E-value: 4.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 335 LTQIP-PLTA-PQITSLELTGNSIASIPDEaFNGLPNLERLDLSKNNITS-PGIGpkafkLLKKLTRLNMDGNNLIQIPS 411
Cdd:COG4886   194 ITDLPePLGNlTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQLTDlPELG-----NLTNLEELDLSNNQLTDLPP 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 412 ELPST-LEELKINENNLQAIDKESLSDLYQLVTLELEGNNLSEVNVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPASIEE 490
Cdd:COG4886   268 LANLTnLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLL 347

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 491 LYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYH 550
Cdd:COG4886   348 ALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLAL 407
VWC smart00214
von Willebrand factor (vWF) type C domain;
103-157 2.48e-12

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 62.15  E-value: 2.48e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622873603  103 CLVKGITMYNKAVWSPEPCTTCLCSDGR-VLCDETMCHP-QRCPQ--TVIPEGECCPVC 157
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTtVLCDPVECPPpPDCPNpeRVKPPGECCPRC 59
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 332-668 2.63e-10

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 63.71  E-value: 2.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 332 NAMLTQIPP--LTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITspGIGPKAFKLLKKLTRLNMDGNNLI-Q 408
Cdd:PLN00113  270 NKLSGPIPPsiFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFT--GKIPVALTSLPRLQVLQLWSNKFSgE 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 409 IPSEL--PSTLEELKINENNLQAIDKESLSDLYQLVTLELEGNNL-SEVnvnPLAFKPLKSLAYLRLGKNKFRiipQGLP 485
Cdd:PLN00113  348 IPKNLgkHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLeGEI---PKSLGACRSLRRVRLQDNSFS---GELP 421

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 486 ASIEELYLennqieeiteicfnhtrkINVIVLRYNKIEeNRIAPLAWiNQENLESIDLSYNKLY-HVP-SYLPKSLLHLV 563
Cdd:PLN00113  422 SEFTKLPL------------------VYFLDISNNNLQ-GRINSRKW-DMPSLQMLSLARNKFFgGLPdSFGSKRLENLD 481

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 564 LLGNQIERIPGYVFGHMePGLEYLYLSFNKLADDGMDRVSfygAYHSLRELFLDHNDLK-SVPPGIQEMKALHFLRLNNN 642
Cdd:PLN00113  482 LSRNQFSGAVPRKLGSL-SELMQLKLSENKLSGEIPDELS---SCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQN 557

                         330       340
                  ....*....|....*....|....*.
gi 1622873603 643 KIRNILPEEICNAEEDDDSNLEHLHL 668
Cdd:PLN00113  558 QLSGEIPKNLGNVESLVQVNISHNHL 583
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 344-548 8.73e-10

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 61.34  E-value: 8.73e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 344 PQITSLELTGNSI----ASIPDEAFNGLPNLERLDLSKNNITSPGIGP--KAFKLLKKLTRLNMDGNNL-----IQIPSE 412
Cdd:COG5238   208 TTVTTLWLKRNPIgdegAEILAEALKGNKSLTTLDLSNNQIGDEGVIAlaEALKNNTTVETLYLSGNQIgaegaIALAKA 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 413 L--PSTLEELKINENNLQAIDKESLSDLYQ----LVTLELEGNNLSEVNVNPL--AFKPLKSLAYLRLGKNKfrIIPQGL 484
Cdd:COG5238   288 LqgNTTLTSLDLSVNRIGDEGAIALAEGLQgnktLHTLNLAYNGIGAQGAIALakALQENTTLHSLDLSDNQ--IGDEGA 365

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622873603 485 PASIEelYLENNQieeiteicfnHTRKINvivLRYNKI-EENRIAPLAWINQENLESIDLSYNKL 548
Cdd:COG5238   366 IALAK--YLEGNT----------TLRELN---LGKNNIgKQGAEALIDALQTNRLHTLILDGNLI 415
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 345-671 8.80e-10

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 62.17  E-value: 8.80e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 345 QITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSPgIGPKAFKLLKKLTRLNMDGNNLI-QIPSELPSTLEELKIN 423
Cdd:PLN00113   70 RVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGP-IPDDIFTTSSSLRYLNLSNNNFTgSIPRGSIPNLETLDLS 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 424 ENNLQAIDKESLSDLYQLVTLELEGNNLseVNVNPLAFKPLKSLAYLRLGKNKFriiPQGLPASIEELylennqieeite 503
Cdd:PLN00113  149 NNMLSGEIPNDIGSFSSLKVLDLGGNVL--VGKIPNSLTNLTSLEFLTLASNQL---VGQIPRELGQM------------ 211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 504 icfnhtRKINVIVLRYNKIE---ENRIAPLAWINQenlesIDLSYNKLyhvPSYLPKSLLHLvllgnqieripgyvfghm 580
Cdd:PLN00113  212 ------KSLKWIYLGYNNLSgeiPYEIGGLTSLNH-----LDLVYNNL---TGPIPSSLGNL------------------ 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 581 ePGLEYLYLSFNKLADdgmdrvsfygayhslrelfldhndlkSVPPGIQEMKALHFLRLNNNKIRNILPEEICNAEeddd 660
Cdd:PLN00113  260 -KNLQYLFLYQNKLSG--------------------------PIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQ---- 308

                         330
                  ....*....|.
gi 1622873603 661 sNLEHLHLENN 671
Cdd:PLN00113  309 -NLEILHLFSN 318
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 335-505 1.28e-09

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 58.64  E-value: 1.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 335 LTQIPPL-TAPQITSLELTGNSIASIpdEAFNGLPNLERLDLSKNNITSpgigpkafklLKKLTRLNMdgnnliqipsel 413
Cdd:cd21340    36 ITKIENLeFLTNLTHLYLQNNQIEKI--ENLENLVNLKKLYLGGNRISV----------VEGLENLTN------------ 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 414 pstLEELKINENNLQ-----AIDKESLSDL-YQLVTLELEGNNLSEvnvnplafkpLKSLAYLRlgknkfriipqglpaS 487
Cdd:cd21340    92 ---LEELHIENQRLPpgeklTFDPRSLAALsNSLRVLNISGNNIDS----------LEPLAPLR---------------N 143

                         170
                  ....*....|....*...
gi 1622873603 488 IEELYLENNQIEEITEIC 505
Cdd:cd21340   144 LEQLDASNNQISDLEELL 161
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 393-575 1.49e-09

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 58.64  E-value: 1.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 393 LKKLTRLNMDGNNLIQIPS-ELPSTLEELKINENNLQAIdkESLSDLYQLVTLELEGNNLSEVNVnplaFKPLKSLAYLR 471
Cdd:cd21340     1 LKRITHLYLNDKNITKIDNlSLCKNLKVLYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKIEN----LENLVNLKKLY 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 472 LGKNKFRIIpQGL--PASIEELYLENNQIEEITEICFNhTRKINVIV--LRYNKIEENRIAPLAWINQ-ENLESIDLSYN 546
Cdd:cd21340    75 LGGNRISVV-EGLenLTNLEELHIENQRLPPGEKLTFD-PRSLAALSnsLRVLNISGNNIDSLEPLAPlRNLEQLDASNN 152

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1622873603 547 KLYHVPSYLP-----KSLLHLVLLGNQIERIPGY 575
Cdd:cd21340   153 QISDLEELLDllsswPSLRELDLTGNPVCKKPKY 186
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
313-573 2.98e-09

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 60.56  E-value: 2.98e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 313 GTLRLPSGCSLSYRTISCINAMLTQIPPLtAPQITSLELTGNSIASIPDEAfnglPNLERLDLSKNNITSPGIGPKAfkl 392
Cdd:PRK15387  212 GLTTLPDCLPAHITTLVIPDNNLTSLPAL-PPELRTLEVSGNQLTSLPVLP----PGLLELSIFSNPLTHLPALPSG--- 283

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 393 lkkLTRLNMDGNNLIQIPSeLPSTLEELKINENNLQaidkeSLSDL-YQLVTLELEGNNLSEVNVNPlafkplKSLAYLR 471
Cdd:PRK15387  284 ---LCKLWIFGNQLTSLPV-LPPGLQELSVSDNQLA-----SLPALpSELCKLWAYNNQLTSLPTLP------SGLQELS 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 472 LGKNKFRIIPQgLPASIEELYLENNQIEEITEICFNHTRKInvivlrynkIEENRIAPLAWINQEnLESIDLSYNKLYHV 551
Cdd:PRK15387  349 VSDNQLASLPT-LPSELYKLWAYNNRLTSLPALPSGLKELI---------VSGNRLTSLPVLPSE-LKELMVSGNRLTSL 417

                         250       260
                  ....*....|....*....|..
gi 1622873603 552 PsYLPKSLLHLVLLGNQIERIP 573
Cdd:PRK15387  418 P-MLPSGLLSLSVYRNQLTRLP 438
LRR_8 pfam13855
Leucine rich repeat;
368-451 1.24e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.76  E-value: 1.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 368 PNLERLDLSKNNITSpgIGPKAFKLLKKLTRLNmdgnnliqipselpstleelkINENNLQAIDKESLSDLYQLVTLELE 447
Cdd:pfam13855   1 PNLRSLDLSNNRLTS--LDDGAFKGLSNLKVLD---------------------LSNNLLTTLSPGAFSGLPSLRYLDLS 57


                  ....
gi 1622873603 448 GNNL 451
Cdd:pfam13855  58 GNRL 61
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
399-680 2.77e-08

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 57.09  E-value: 2.77e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 399 LNMDGNNLIQIPSELPSTLEELKINENNLQaidkeSLSDL-YQLVTLELEGNNLSEVNV------------NPLAFKPL- 464
Cdd:PRK15387  206 LNVGESGLTTLPDCLPAHITTLVIPDNNLT-----SLPALpPELRTLEVSGNQLTSLPVlppgllelsifsNPLTHLPAl 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 465 -KSLAYLRLGKNKFRIIPQgLPASIEELYLENNQIEEI----TEICfnhtrkinvIVLRYNkieeNRIAPLAWInQENLE 539
Cdd:PRK15387  281 pSGLCKLWIFGNQLTSLPV-LPPGLQELSVSDNQLASLpalpSELC---------KLWAYN----NQLTSLPTL-PSGLQ 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 540 SIDLSYNKLYHVPSyLPKSLLHLVLLGNQIERIPGyvfghMEPGLEYLYLSFNKLaddgmdrVSFYGAYHSLRELFLDHN 619
Cdd:PRK15387  346 ELSVSDNQLASLPT-LPSELYKLWAYNNRLTSLPA-----LPSGLKELIVSGNRL-------TSLPVLPSELKELMVSGN 412

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622873603 620 DLKSVPPGIQEMKALHFLRlnNNKIRniLPEEICNAEEDDDSNLEHLHLENNYIK-IREIPS 680
Cdd:PRK15387  413 RLTSLPMLPSGLLSLSVYR--NQLTR--LPESLIHLSSETTVNLEGNPLSERTLQaLREITS 470
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 491-673 4.50e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 51.33  E-value: 4.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 491 LYLENNQIEEITEicFNHTRKINVIVLRYNKIEenRIaplawinqENLESidlsynklyhvpsyLPKsLLHLVLLGNQIE 570
Cdd:cd21340     7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKIT--KI--------ENLEF--------------LTN-LTHLYLQNNQIE 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 571 RIPGyvFGHMePGLEYLYLSFNKLAddgmdRVSFYGAYHSLRELFLDHNDLksvPPGiQEM-----------KALHFLRL 639
Cdd:cd21340    60 KIEN--LENL-VNLKKLYLGGNRIS-----VVEGLENLTNLEELHIENQRL---PPG-EKLtfdprslaalsNSLRVLNI 127

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1622873603 640 NNNKIRNILPEEICnaeedddSNLEHLHLENNYI 673
Cdd:cd21340   128 SGNNIDSLEPLAPL-------RNLEQLDASNNQI 154
LRR_8 pfam13855
Leucine rich repeat;
415-477 1.12e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.98  E-value: 1.12e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622873603 415 STLEELKINENNLQAIDKESLSDLYQLVTLELEGNNLSEvnVNPLAFKPLKSLAYLRLGKNKF 477
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
537-594 2.57e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.21  E-value: 2.57e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622873603 537 NLESIDLSYNKLYHVPSYLPKSLLHLVLL---GNQIERIPGYVFGHMePGLEYLYLSFNKL 594
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLdlsNNLLTTLSPGAFSGL-PSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
558-621 3.95e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.44  E-value: 3.95e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622873603 558 SLLHLVLLGNQIERIPGYVFGHMePGLEYLYLSFNKLadDGMDRVSFYGaYHSLRELFLDHNDL 621
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGL-SNLKVLDLSNNLL--TTLSPGAFSG-LPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 493-695 5.35e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 48.89  E-value: 5.35e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 493 LENNQIEEITEICFNHTRKINVIVlrynkieenRIAPLAWINQENLESIDLSYNKLYH-----VPSYLPKSLL-HLVL-- 564
Cdd:cd00116    47 LRPQPSLKELCLSLNETGRIPRGL---------QSLLQGLTKGCGLQELDLSDNALGPdgcgvLESLLRSSSLqELKLnn 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 565 --LGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVS-FYGAYHSLRELFLDHNDLKsvPPGI----QEMKA---L 634
Cdd:cd00116   118 ngLGDRGLRLLAKGLKDLPPALEKLVLGRNRLEGASCEALAkALRANRDLKELNLANNGIG--DAGIralaEGLKAncnL 195

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622873603 635 HFLRLNNNKIRNILPEEICNAEEDDDSnLEHLHLENNyiKIREIPSYTFSCIRSYSSIVLK 695
Cdd:cd00116   196 EVLDLNNNGLTDEGASALAETLASLKS-LEVLNLGDN--NLTDAGAAALASALLSPNISLL 253
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 343-477 1.01e-05

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 48.12  E-value: 1.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 343 APQITSLELTGNSIASIPDEA----FNGLPNLERLDLSKNNITSPGIGP--KAFKLLKKLTRLNMDGNNL----IQIPSE 412
Cdd:cd00116   136 PPALEKLVLGRNRLEGASCEAlakaLRANRDLKELNLANNGIGDAGIRAlaEGLKANCNLEVLDLNNNGLtdegASALAE 215

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622873603 413 LPST---LEELKINENNL-----QAIDKESLSDLYQLVTLELEGNNLSEVNVNPLA--FKPLKSLAYLRLGKNKF 477
Cdd:cd00116   216 TLASlksLEVLNLGDNNLtdagaAALASALLSPNISLLTLSLSCNDITDDGAKDLAevLAEKESLLELDLRGNKF 290
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 335-674 1.89e-05

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 47.48  E-value: 1.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 335 LTQIPPLTAPQITSLEltGNSIASIPDEAFNGLPNLERLDLSKNNITspgigpkAFKLlkkltRLNMDGNNlIQIPSELP 414
Cdd:COG5238    15 LLSANPATTEQSELTK--RATIVNLRSYHLHGGAILLARYLQSRSSI-------TQYL-----RFEGQGDP-GLNPVALE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 415 STLE-----ELKINENNLQAIDKESLSDLYQLVT-----LELEGNNLSEVNVNPLA-----------FKPLKSLAYLRLG 473
Cdd:COG5238    80 KAAEafptqLLVVDWEGAEEVSPVALAETATAVAtpppdLRRIMAKTLEDSLILYLalprrinliqvLKDPLGGNAVHLL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 474 KNKFRI--------IPQGLPASIEELYLENNQIEE--ITEICfNHTRK---INVIVLRYNKIEENRIAPLAWINQEN--L 538
Cdd:COG5238   160 GLAARLgllaaismAKALQNNSVETVYLGCNQIGDegIEELA-EALTQnttVTTLWLKRNPIGDEGAEILAEALKGNksL 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 539 ESIDLSYNK-----LYHVPSYL--PKSLLHLVLLGNQIEripgyvfghmEPGLEYL--YLSFNKladdgmdrvsfygayh 609
Cdd:COG5238   239 TTLDLSNNQigdegVIALAEALknNTTVETLYLSGNQIG----------AEGAIALakALQGNT---------------- 292

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 610 SLRELFLDHNDL-----KSVPPGIQEMKALHFLRLNNNKIRNILPEEICNAEEdDDSNLEHLHLENNYIK 674
Cdd:COG5238   293 TLTSLDLSVNRIgdegaIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQ-ENTTLHSLDLSDNQIG 361
LRR_8 pfam13855
Leucine rich repeat;
487-548 2.93e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.13  E-value: 2.93e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622873603 487 SIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIeeNRIAPLAWINQENLESIDLSYNKL 548
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
582-644 3.53e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.74  E-value: 3.53e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622873603 582 PGLEYLYLSFNKLadDGMDRVSFYGAyHSLRELFLDHNDLKSVPPG-IQEMKALHFLRLNNNKI 644
Cdd:pfam13855   1 PNLRSLDLSNNRL--TSLDDGAFKGL-SNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
Amnionless pfam14828
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ...
 116-217 7.07e-05

Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.


Pssm-ID: 464340  Cd Length: 449  Bit Score: 45.84  E-value: 7.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 116 WSPEPC---TTCLCSDGRVLcdETMCH--PQRCPQT-----VIPEGECCPVCSATVSysllsgiaLNDRNEFSGDSSEQR 185
Cdd:pfam14828 186 VGPEACsdpSGCGCGNDENL--ERICAnvLQRCPPPhclspLRPEGHCCDVCGAIVS--------LDYSSCFDLQTYRAR 255

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1622873603 186 eptnLLHKQLPPP-----QVGMDQIVRKEALQSEEDE 217
Cdd:pfam14828 256 ----LRHLFLALPkykgvQLAVSKVGKDQRLHISDNE 288
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 368-415 8.80e-05

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 40.31  E-value: 8.80e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1622873603 368 PNLERLDLSKNNITSpgIGPkaFKLLKKLTRLNMDGNNLIQIPSELPS 415
Cdd:pfam12799   1 PNLEVLDLSNNQITD--IPP--LAKLPNLETLDLSGNNKITDLSDLAN 44
VWC_out smart00215
von Willebrand factor (vWF) type C domain;
103-143 2.00e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214565  Cd Length: 67  Bit Score: 39.85  E-value: 2.00e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1622873603  103 CLVKGITMYNKAVWSpEPCTTCLCSDGRVLCDETMCHPQRC 143
Cdd:smart00215   1 CWNNGSYYPPGAKWD-DDCNRCTCLNGRVSCTKVWCGPKPC 40
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 343-646 2.53e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 44.01  E-value: 2.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 343 APQITSLELTGNSI-----ASIPDEAFNGLPNLERLDLSKNNITSPGIgpkafKLLKKLTRLNMDGNNLIqipselpstL 417
Cdd:COG5238   150 PLGGNAVHLLGLAArlgllAAISMAKALQNNSVETVYLGCNQIGDEGI-----EELAEALTQNTTVTTLW---------L 215

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 418 EELKINENNLQAIdKESLSDLYQLVTLELEGNNLSEVNVNPLAfkplKSLAYlrlgknkfriipqglPASIEELYLENNQ 497
Cdd:COG5238   216 KRNPIGDEGAEIL-AEALKGNKSLTTLDLSNNQIGDEGVIALA----EALKN---------------NTTVETLYLSGNQ 275

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 498 IEEITEICFNHTRKINvIVLRYNKIEENRIAPLAWIN-----QEN--LESIDLSYNKLyhvpsylpksllhlvllGNQ-I 569
Cdd:COG5238   276 IGAEGAIALAKALQGN-TTLTSLDLSVNRIGDEGAIAlaeglQGNktLHTLNLAYNGI-----------------GAQgA 337

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 570 ERIPGYVFGHmePGLEYLYLSFNKLADDGMDRVSFYGAYH-SLRELFLDHNDLKSVppGIQEMKA------LHFLRLNNN 642
Cdd:COG5238   338 IALAKALQEN--TTLHSLDLSDNQIGDEGAIALAKYLEGNtTLRELNLGKNNIGKQ--GAEALIDalqtnrLHTLILDGN 413


                  ....
gi 1622873603 643 KIRN 646
Cdd:COG5238   414 LIGA 417
LRR_8 pfam13855
Leucine rich repeat;
610-673 4.12e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.04  E-value: 4.12e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622873603 610 SLRELFLDHNDLKSVPPGI-QEMKALHFLRLNNNKIRNILPEEIcnaeeDDDSNLEHLHLENNYI 673
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSPGAF-----SGLPSLRYLDLSGNRL 61
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 344-379 1.48e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 36.84  E-value: 1.48e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1622873603 344 PQITSLELTGNSIASIPdeAFNGLPNLERLDLSKNN 379
Cdd:pfam12799   1 PNLEVLDLSNNQITDIP--PLAKLPNLETLDLSGNN 34
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 344-421 2.85e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 40.54  E-value: 2.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 344 PQITSLELTGNSI----ASIPDEAFNGLPNLERLDLSKNNITSPGigpkAFKLLK-----KLTRLNMDGNNL-IQIPSEL 413
Cdd:COG5238   348 TTLHSLDLSDNQIgdegAIALAKYLEGNTTLRELNLGKNNIGKQG----AEALIDalqtnRLHTLILDGNLIgAEAQQRL 423


                  ....*...
gi 1622873603 414 PSTLEELK 421
Cdd:COG5238   424 EQLLERIK 431
PLN03150 PLN03150
hypothetical protein; Provisional
 348-417 4.23e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 40.18  E-value: 4.23e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622873603 348 SLELTGNSIASIPDEAFNGLPNLERLDLSKNNITspGIGPKAFKLLKKLTRLNMDGNNLiqiPSELPSTL 417
Cdd:PLN03150  446 SINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFN--GSIPESLGQLTSLRILNLNGNSL---SGRVPAAL 510
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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