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Conserved domains on  [gi|966990908|ref|XP_014972389|]
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ribosome-recycling factor, mitochondrial isoform X5 [Macaca mulatta]

Protein Classification

ribosome-recycling factor( domain architecture ID 797)

ribosome-recycling factor is responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis

CATH:  1.10.132.20|3.30.1360.40
Gene Ontology:  GO:0043023|GO:0006412|GO:0006415

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RRF super family cl00240
Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination ...
 177-222 2.10e-07

Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are "recycled" and ready for another round of protein synthesis. RRF is believed to bind the ribosome at the A-site in a manner that mimics tRNA, but the specific mechanisms remain unclear. RRF is essential for bacterial growth. It is not necessary for cell growth in archaea or eukaryotes, but is found in mitochondria or chloroplasts of some eukaryotic species.


The actual alignment was detected with superfamily member pfam01765:

Pssm-ID: 469680  Cd Length: 158  Bit Score: 49.36  E-value: 2.10e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 966990908  177 FNKTLNIRTSPGSLDKIAVVTADGKLALNQIGQISMKSPQLILVNM 222
Cdd:pfam01765   1 LAKIRTGRANPSLLDNIKVDYYGSPTPLNQLAQVSVPEARTLVITP 46
 
Name Accession Description Interval E-value
RRF pfam01765
Ribosome recycling factor; The ribosome recycling factor (RRF / ribosome release factor) ...
 177-222 2.10e-07

Ribosome recycling factor; The ribosome recycling factor (RRF / ribosome release factor) dissociates the ribosome from the mRNA after termination of translation, and is essential bacterial growth. Thus ribosomes are "recycled" and ready for another round of protein synthesis.


Pssm-ID: 460316  Cd Length: 158  Bit Score: 49.36  E-value: 2.10e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 966990908  177 FNKTLNIRTSPGSLDKIAVVTADGKLALNQIGQISMKSPQLILVNM 222
Cdd:pfam01765   1 LAKIRTGRANPSLLDNIKVDYYGSPTPLNQLAQVSVPEARTLVITP 46
 
Name Accession Description Interval E-value
RRF pfam01765
Ribosome recycling factor; The ribosome recycling factor (RRF / ribosome release factor) ...
 177-222 2.10e-07

Ribosome recycling factor; The ribosome recycling factor (RRF / ribosome release factor) dissociates the ribosome from the mRNA after termination of translation, and is essential bacterial growth. Thus ribosomes are "recycled" and ready for another round of protein synthesis.


Pssm-ID: 460316  Cd Length: 158  Bit Score: 49.36  E-value: 2.10e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 966990908  177 FNKTLNIRTSPGSLDKIAVVTADGKLALNQIGQISMKSPQLILVNM 222
Cdd:pfam01765   1 LAKIRTGRANPSLLDNIKVDYYGSPTPLNQLAQVSVPEARTLVITP 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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