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Conserved domains on  [gi|966990583|ref|XP_014972236|]
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cip1-interacting zinc finger protein isoform X6 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
128-424 2.93e-07

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 54.56  E-value: 2.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  128 PSLTTPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPnrkdsSSQTMPVEDKS 207
Cdd:PHA03247 2703 PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGP-----PAPAPPAAPAA 2777
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  208 DPPEGSeeAAEPGMDTSEDQDLPPCPEDigkekctaaPEPEPCEVSePPAKRLRSSEEPTEKEPPgqlqakaQPQARMTV 287
Cdd:PHA03247 2778 GPPRRL--TRPAVASLSESRESLPSPWD---------PADPPAAVL-APAAALPPAASPAGPLPP-------PTSAQPTA 2838
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  288 PKQTQTPDLLPEPLEAQVLP-----RFQPRvlqiQAQVQSQTQPRIPPTDAQVQPKLQKQAQTQTSPehlvlqqkQVQPQ 362
Cdd:PHA03247 2839 PPPPPGPPPPSLPLGGSVAPggdvrRRPPS----RSPAAKPAAPARPPVRRLARPAVSRSTESFALP--------PDQPE 2906
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966990583  363 LQQEAEPQKQMQPQVHTQAQPRVQPQEQPPAQVPVQPPEQTHEQPQTQPQVSVLAPEQTPVV 424
Cdd:PHA03247 2907 RPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALV 2968
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
628-652 1.22e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


:

Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.54  E-value: 1.22e-05
                          10        20
                  ....*....|....*....|....*
gi 966990583  628 FCTVCNRYFKTPRKFVEHVKSQGHK 652
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
534-563 4.81e-04

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 38.39  E-value: 4.81e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 966990583   534 QFFCYICKASCSSQQEFQDHMSEPQHQQRL 563
Cdd:smart00451   3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNV 32
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
739-772 1.09e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 37.23  E-value: 1.09e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 966990583   739 GYVCRICHKFyHSNSGAQLSHCKSLGHFENLQKY 772
Cdd:smart00451   3 GFYCKLCNVT-FTDEISVEAHLKGKKHKKNVKKR 35
UFD2 super family cl40793
U1-like Zn-finger-containing protein [General function prediction only];
608-659 3.93e-03

U1-like Zn-finger-containing protein [General function prediction only];


The actual alignment was detected with superfamily member COG5112:

Pssm-ID: 227443  Cd Length: 126  Bit Score: 38.14  E-value: 3.93e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583 608 DLIQHRRTQDHKIAKQSLRP--------FCTVCNRYFKTPRKFVEHVKSQGHKDKAKELK 659
Cdd:COG5112   29 DQIKNDLSTKESQKKLPYDPelpglgqhYCIECARYFITEKALMEHKKGKVHKRRAKELR 88
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
128-424 2.93e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 54.56  E-value: 2.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  128 PSLTTPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPnrkdsSSQTMPVEDKS 207
Cdd:PHA03247 2703 PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGP-----PAPAPPAAPAA 2777
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  208 DPPEGSeeAAEPGMDTSEDQDLPPCPEDigkekctaaPEPEPCEVSePPAKRLRSSEEPTEKEPPgqlqakaQPQARMTV 287
Cdd:PHA03247 2778 GPPRRL--TRPAVASLSESRESLPSPWD---------PADPPAAVL-APAAALPPAASPAGPLPP-------PTSAQPTA 2838
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  288 PKQTQTPDLLPEPLEAQVLP-----RFQPRvlqiQAQVQSQTQPRIPPTDAQVQPKLQKQAQTQTSPehlvlqqkQVQPQ 362
Cdd:PHA03247 2839 PPPPPGPPPPSLPLGGSVAPggdvrRRPPS----RSPAAKPAAPARPPVRRLARPAVSRSTESFALP--------PDQPE 2906
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966990583  363 LQQEAEPQKQMQPQVHTQAQPRVQPQEQPPAQVPVQPPEQTHEQPQTQPQVSVLAPEQTPVV 424
Cdd:PHA03247 2907 RPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALV 2968
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
628-652 1.22e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.54  E-value: 1.22e-05
                          10        20
                  ....*....|....*....|....*
gi 966990583  628 FCTVCNRYFKTPRKFVEHVKSQGHK 652
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
Agg_substance NF033875
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ...
105-296 3.93e-05

LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.


Pssm-ID: 411439 [Multi-domain]  Cd Length: 1306  Bit Score: 47.40  E-value: 3.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  105 LTMPTATLGNLRGYGMASPGLAAPSL-TTPSLTPPQLATPNLQqffpqatrqsllgpppvgvpmnpsqfnlSGRNPQKQA 183
Cdd:NF033875   21 VVAPILFLGVLGVVGLATDNVQAAELdTQPGTTTVQPDNPDPQ----------------------------SGSETPKTA 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  184 RTSSSTTpnRKDSSSQTMPVEDKSDPPEGSEEAAEPGMDTSEDQDLPPCPEDIGKEKCTAAPEpepcEVSEPPAkrlrss 263
Cdd:NF033875   73 VSEEATV--QKDTTSQPTKVEEVASEKNGAEQSSATPNDTTNAQQPTVGAEKSAQEQPVVSPE----TTNEPLG------ 140
                         170       180       190
                  ....*....|....*....|....*....|...
gi 966990583  264 eEPTEKEPpgqlqAKAQPQARMTVPKQTQTPDL 296
Cdd:NF033875  141 -QPTEVAP-----AENEANKSTSIPKEFETPDV 167
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
534-563 4.81e-04

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 38.39  E-value: 4.81e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 966990583   534 QFFCYICKASCSSQQEFQDHMSEPQHQQRL 563
Cdd:smart00451   3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNV 32
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
739-772 1.09e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 37.23  E-value: 1.09e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 966990583   739 GYVCRICHKFyHSNSGAQLSHCKSLGHFENLQKY 772
Cdd:smart00451   3 GFYCKLCNVT-FTDEISVEAHLKGKKHKKNVKKR 35
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
230-442 3.04e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 41.17  E-value: 3.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  230 PPCPEDIGKEKCTAAPEPEPCEVSEP---PAKRLRSSEEP-TEKEPPGQLQAKA--------QPQARMTVPKQTQTPDLL 297
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQsqqPSKPVRTGYEKyKEPEPIPDLQVDAslwgvapkKAAAPAPAPQPAAQPASL 186
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  298 PEP---------LEAQVlpRFQPRVLQIQAQVQSQTQPRIPPTdAQVQPKLQKQAQTQTSPEHlvlqqkqvqpqlqqeaE 368
Cdd:pfam09770 187 PAPsrkmmsleeVEAAM--RAQAKKPAQQPAPAPAQPPAAPPA-QQAQQQQQFPPQIQQQQQP----------------Q 247
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966990583  369 PQKQMQPQVHTQAQP-----RVQPQEQPPAQVPVQPPEQTHEQPQTQPQVSVLAPEQTPVVVDVCGLEMPPDAVEAGGG 442
Cdd:pfam09770 248 QQPQQPQQHPGQGHPvtilqRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQP 326
UFD2 COG5112
U1-like Zn-finger-containing protein [General function prediction only];
608-659 3.93e-03

U1-like Zn-finger-containing protein [General function prediction only];


Pssm-ID: 227443  Cd Length: 126  Bit Score: 38.14  E-value: 3.93e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583 608 DLIQHRRTQDHKIAKQSLRP--------FCTVCNRYFKTPRKFVEHVKSQGHKDKAKELK 659
Cdd:COG5112   29 DQIKNDLSTKESQKKLPYDPelpglgqhYCIECARYFITEKALMEHKKGKVHKRRAKELR 88
GIY-YIG_PLEs cd10442
Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This ...
597-664 5.81e-03

Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This model corresponds to the EN domain of PLEs that contains catalytic module of the GIY-YIG endonucleases of group I bacterial/organellar introns, as well as bacterial UvrC DNA repair proteins. It can cleave DNA with low nucleotide sequence specificity. However, the PLEs EN domain is distinct from other GIY-YIG endonucleases by the presence of a well-conserved CCHH motif (CX(2-7)CX(33-39)HX(3-5)H, X can be any residue). The role of the CCHH motif has not yet been identified. Penelope-like elements (PLEs) represent a novel class of eukaryotic retroelements, which do not belong to either long terminal repeat (LTR) retrotransposons or non-LTR retrotransposons (often called LINEs), but instead form a sister clade to telomerase reverse transcriptases (TERTs), highly specialized non-mobile reverse transcriptases (RTs) which are responsible for the addition of telomeric repeats to the ends of eukaryotic chromosomes. The single open reading frame (ORF) encoded by PLE consists of two principal domains, RT domain and endonuclease (EN) domain, jointed by a linker region of variable length. Both of these two domains are functionally active.


Pssm-ID: 198389  Cd Length: 92  Bit Score: 36.96  E-value: 5.81e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583 597 WCNTCQLYYVGDLIQ--HRRTQDHKIAKQSlrpfctvcNRYFKTPrkFVEHVKSQGHKDKAKELKSLEKE 664
Cdd:cd10442    6 PCPKCGLVYIGETKRplRERMKEHRRAIRL--------SGTKKSA--VAKHFNEEGHSIDSDRVRILDKE 65
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
128-424 2.93e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 54.56  E-value: 2.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  128 PSLTTPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPnrkdsSSQTMPVEDKS 207
Cdd:PHA03247 2703 PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGP-----PAPAPPAAPAA 2777
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  208 DPPEGSeeAAEPGMDTSEDQDLPPCPEDigkekctaaPEPEPCEVSePPAKRLRSSEEPTEKEPPgqlqakaQPQARMTV 287
Cdd:PHA03247 2778 GPPRRL--TRPAVASLSESRESLPSPWD---------PADPPAAVL-APAAALPPAASPAGPLPP-------PTSAQPTA 2838
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  288 PKQTQTPDLLPEPLEAQVLP-----RFQPRvlqiQAQVQSQTQPRIPPTDAQVQPKLQKQAQTQTSPehlvlqqkQVQPQ 362
Cdd:PHA03247 2839 PPPPPGPPPPSLPLGGSVAPggdvrRRPPS----RSPAAKPAAPARPPVRRLARPAVSRSTESFALP--------PDQPE 2906
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966990583  363 LQQEAEPQKQMQPQVHTQAQPRVQPQEQPPAQVPVQPPEQTHEQPQTQPQVSVLAPEQTPVV 424
Cdd:PHA03247 2907 RPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALV 2968
PHA03247 PHA03247
large tegument protein UL36; Provisional
93-350 1.93e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.86  E-value: 1.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583   93 FAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTTPSLTPPQLATPNLQ-QFFPQATRQSLLGPP---PVGVPMN 168
Cdd:PHA03247 2698 LADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPgGPARPARPPTTAGPPapaPPAAPAA 2777
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  169 PSQFNLSgRNPQKQARTSSSTTPNRKDSSSQTMPV--EDKSDPPEGSEEAAEPGMDTSEDQDLPPCPEDIgkekctaaPE 246
Cdd:PHA03247 2778 GPPRRLT-RPAVASLSESRESLPSPWDPADPPAAVlaPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPP--------PP 2848
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  247 PEPCEVSEPPAKRLRssEEPTEKEPPGQLQAKAQPQARM----TVPKQTQT----PDLLPEPLEAQVLPRFQPrvlQIQA 318
Cdd:PHA03247 2849 SLPLGGSVAPGGDVR--RRPPSRSPAAKPAAPARPPVRRlarpAVSRSTESfalpPDQPERPPQPQAPPPPQP---QPQP 2923
                         250       260       270
                  ....*....|....*....|....*....|..
gi 966990583  319 QVQSQTQPRiPPTDAQVQPKLQKQAQTQTSPE 350
Cdd:PHA03247 2924 PPPPQPQPP-PPPPPRPQPPLAPTTDPAGAGE 2954
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
628-652 1.22e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.54  E-value: 1.22e-05
                          10        20
                  ....*....|....*....|....*
gi 966990583  628 FCTVCNRYFKTPRKFVEHVKSQGHK 652
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
PHA03247 PHA03247
large tegument protein UL36; Provisional
96-439 2.22e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 2.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583   96 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTTPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLS 175
Cdd:PHA03247 2577 PSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDP 2656
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  176 G----------RNPQKQARTSSSTT-PNRKDSSSQTMPVEDKSDPPEGSEEAAEPGMDTSEDQDLPPCPEDIGKEK--CT 242
Cdd:PHA03247 2657 ApgrvsrprraRRLGRAAQASSPPQrPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASpaLP 2736
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  243 AAPEPEPC-EVSEPPAKRLRSSEEPTEKEPPGQLQAKAQ---PQARMTVP---KQTQTPDLLPEPLEAQVLPRFQPRVLQ 315
Cdd:PHA03247 2737 AAPAPPAVpAGPATPGGPARPARPPTTAGPPAPAPPAAPaagPPRRLTRPavaSLSESRESLPSPWDPADPPAAVLAPAA 2816
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  316 IQAQVQSQTQPRIPPTDAQVQPKLQKQAQTQT---------------------SPEHLVLQQKQVQPQLQQEAEPQKQMQ 374
Cdd:PHA03247 2817 ALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPslplggsvapggdvrrrppsrSPAAKPAAPARPPVRRLARPAVSRSTE 2896
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966990583  375 PQVHTQAQPRVQPQEQPPAQVPVQPPEQTHEQPQTQPQVSVLAPEQTPVVVDVCGLEMPPDAVEA 439
Cdd:PHA03247 2897 SFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQ 2961
Agg_substance NF033875
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ...
105-296 3.93e-05

LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.


Pssm-ID: 411439 [Multi-domain]  Cd Length: 1306  Bit Score: 47.40  E-value: 3.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  105 LTMPTATLGNLRGYGMASPGLAAPSL-TTPSLTPPQLATPNLQqffpqatrqsllgpppvgvpmnpsqfnlSGRNPQKQA 183
Cdd:NF033875   21 VVAPILFLGVLGVVGLATDNVQAAELdTQPGTTTVQPDNPDPQ----------------------------SGSETPKTA 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  184 RTSSSTTpnRKDSSSQTMPVEDKSDPPEGSEEAAEPGMDTSEDQDLPPCPEDIGKEKCTAAPEpepcEVSEPPAkrlrss 263
Cdd:NF033875   73 VSEEATV--QKDTTSQPTKVEEVASEKNGAEQSSATPNDTTNAQQPTVGAEKSAQEQPVVSPE----TTNEPLG------ 140
                         170       180       190
                  ....*....|....*....|....*....|...
gi 966990583  264 eEPTEKEPpgqlqAKAQPQARMTVPKQTQTPDL 296
Cdd:NF033875  141 -QPTEVAP-----AENEANKSTSIPKEFETPDV 167
PRK10263 PRK10263
DNA translocase FtsK; Provisional
262-427 2.19e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 45.08  E-value: 2.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  262 SSEEPTEKEPP--GQLQAKAQPQAR-MTVP-KQTQTPDLLPEPLEAQVLPRFQPRVLQIQAQVQSQTQPRIPPTDAQVQP 337
Cdd:PRK10263  335 APVEPVTQTPPvaSVDVPPAQPTVAwQPVPgPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQ 414
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  338 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQMQPQVHTQAQPRVQPQEqppAQVPVQPPEQTHEQPQTQPQVSVLA 417
Cdd:PRK10263  415 PAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQ---TYQQPAAQEPLYQQPQPVEQQPVVE 491
                         170
                  ....*....|
gi 966990583  418 PEqtPVVVDV 427
Cdd:PRK10263  492 PE--PVVEET 499
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
534-563 4.81e-04

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 38.39  E-value: 4.81e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 966990583   534 QFFCYICKASCSSQQEFQDHMSEPQHQQRL 563
Cdd:smart00451   3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNV 32
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
739-772 1.09e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 37.23  E-value: 1.09e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 966990583   739 GYVCRICHKFyHSNSGAQLSHCKSLGHFENLQKY 772
Cdd:smart00451   3 GFYCKLCNVT-FTDEISVEAHLKGKKHKKNVKKR 35
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
163-348 2.22e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 41.57  E-value: 2.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583 163 VGVPMNPSQFNLSGRNPQKQARTSSSttpnrkdSSSQTMPVEDKSDPP-EGSEEAAEPGMDTSEDQDLPPCPEdigkekc 241
Cdd:PRK14960 368 VSEPVQQNGQAEVGLNSQAQTAQEIT-------PVSAVQPVEVISQPAmVEPEPEPEPEPEPEPEPEPEPEPE------- 433
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583 242 taaPEPEPcEVSEPPAKRLRSSEePTEKEPPGQLQAKAQpqarmtVPKQTQTPDLLPEPLEAQVLPRFQPRVLQIQAQVQ 321
Cdd:PRK14960 434 ---PEPEP-EPEPQPNQDLMVFD-PNHHELIGLESAVVQ------ETVSVLEEDFIPVPEQKLVQVQAETQVKQIEPEPA 502
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 966990583 322 SQTQP---------------RIPPTDAQVQPKLQKQAQTQTS 348
Cdd:PRK14960 503 STAEPiglfeassaefslaqDTSAYDLVSEPVIEQQSLVQAE 544
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
230-442 3.04e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 41.17  E-value: 3.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  230 PPCPEDIGKEKCTAAPEPEPCEVSEP---PAKRLRSSEEP-TEKEPPGQLQAKA--------QPQARMTVPKQTQTPDLL 297
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQsqqPSKPVRTGYEKyKEPEPIPDLQVDAslwgvapkKAAAPAPAPQPAAQPASL 186
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583  298 PEP---------LEAQVlpRFQPRVLQIQAQVQSQTQPRIPPTdAQVQPKLQKQAQTQTSPEHlvlqqkqvqpqlqqeaE 368
Cdd:pfam09770 187 PAPsrkmmsleeVEAAM--RAQAKKPAQQPAPAPAQPPAAPPA-QQAQQQQQFPPQIQQQQQP----------------Q 247
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966990583  369 PQKQMQPQVHTQAQP-----RVQPQEQPPAQVPVQPPEQTHEQPQTQPQVSVLAPEQTPVVVDVCGLEMPPDAVEAGGG 442
Cdd:pfam09770 248 QQPQQPQQHPGQGHPvtilqRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQP 326
UFD2 COG5112
U1-like Zn-finger-containing protein [General function prediction only];
608-659 3.93e-03

U1-like Zn-finger-containing protein [General function prediction only];


Pssm-ID: 227443  Cd Length: 126  Bit Score: 38.14  E-value: 3.93e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583 608 DLIQHRRTQDHKIAKQSLRP--------FCTVCNRYFKTPRKFVEHVKSQGHKDKAKELK 659
Cdd:COG5112   29 DQIKNDLSTKESQKKLPYDPelpglgqhYCIECARYFITEKALMEHKKGKVHKRRAKELR 88
GIY-YIG_PLEs cd10442
Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This ...
597-664 5.81e-03

Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This model corresponds to the EN domain of PLEs that contains catalytic module of the GIY-YIG endonucleases of group I bacterial/organellar introns, as well as bacterial UvrC DNA repair proteins. It can cleave DNA with low nucleotide sequence specificity. However, the PLEs EN domain is distinct from other GIY-YIG endonucleases by the presence of a well-conserved CCHH motif (CX(2-7)CX(33-39)HX(3-5)H, X can be any residue). The role of the CCHH motif has not yet been identified. Penelope-like elements (PLEs) represent a novel class of eukaryotic retroelements, which do not belong to either long terminal repeat (LTR) retrotransposons or non-LTR retrotransposons (often called LINEs), but instead form a sister clade to telomerase reverse transcriptases (TERTs), highly specialized non-mobile reverse transcriptases (RTs) which are responsible for the addition of telomeric repeats to the ends of eukaryotic chromosomes. The single open reading frame (ORF) encoded by PLE consists of two principal domains, RT domain and endonuclease (EN) domain, jointed by a linker region of variable length. Both of these two domains are functionally active.


Pssm-ID: 198389  Cd Length: 92  Bit Score: 36.96  E-value: 5.81e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966990583 597 WCNTCQLYYVGDLIQ--HRRTQDHKIAKQSlrpfctvcNRYFKTPrkFVEHVKSQGHKDKAKELKSLEKE 664
Cdd:cd10442    6 PCPKCGLVYIGETKRplRERMKEHRRAIRL--------SGTKKSA--VAKHFNEEGHSIDSDRVRILDKE 65
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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