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Conserved domains on  [gi|1622865008|ref|XP_014970565|]
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nuclear mitotic apparatus protein 1 isoform X1 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
6-152 7.95e-58

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


:

Pssm-ID: 411795  Cd Length: 148  Bit Score: 196.64  E-value: 7.95e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008    6 TRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRLHGTEEGQQILQQPVPERLDFVCSFLQKNQKHPSSPECLVSAQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622865008   86 KVLEG--SELELAKMTMLLLYHSTMSSKSPrdWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLR 152
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
1870-1928 1.25e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


:

Pssm-ID: 412093  Cd Length: 56  Bit Score: 104.22  E-value: 1.25e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622865008 1870 LLSLPGYRPTTRSSARRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1928
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
560-1200 1.41e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 115.80  E-value: 1.41e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  560 LKQKEQQLKEVAEKQEVTRRdhAQQLATAAEEREASLRerdaalqqlealekekAAKLEILQQQLQVANETRDSAQTSVT 639
Cdd:COG1196    195 LGELERQLEPLERQAEKAER--YRELKEELKELEAELL----------------LLKLRELEAELEELEAELEELEAELE 256
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  640 QAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQkatEKERVAQEKDQLQEQLQALKESLKVTKGSLE 719
Cdd:COG1196    257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ---DIARLEERRRELEERLEELEEELAELEEELE 333
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  720 EEKRRAADALEEQQrcisELKAETRSLVEQHKQEQKELEEEKAGRkglearlqqlgEAHQAETEALRQELAEAIAAQRTA 799
Cdd:COG1196    334 ELEEELEELEEELE----EAEEELEEAEAELAEAEEALLEAEAEL-----------AEAEEELEELAEELLEALRAAAEL 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  800 ESECEQLVKEVAAWRERYEESQQEEAQYgamfQEQLMTLKEECEKARQELQEAKEKVAGIEShSELQISRQQNELVELHA 879
Cdd:COG1196    399 AAQLEELEEAEEALLERLERLEEELEEL----EEALAELEEEEEEEEEALEEAAEEEAELEE-EEEALLELLAELLEEAA 473
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  880 NLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDREPEwLEEQQGRQ 959
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAL-AAALQNIV 552
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  960 FCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALN 1039
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1040 EQRVEFA-TLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASgsgaqseaagrtept 1118
Cdd:COG1196    633 EAALRRAvTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE--------------- 697
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1119 gpKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTK 1198
Cdd:COG1196    698 --ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775

                   ..
gi 1622865008 1199 VQ 1200
Cdd:COG1196    776 IE 777
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
209-891 2.26e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 115.54  E-value: 2.26e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  209 LQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL-ALLNEKQAASPLEPRELEELRDKNES 287
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALaNEISRLEQQKQILRERLANLERQLEE 320
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  288 LTMRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEH---SRATQEWLEKQAQLEK 364
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetlRSKVAQLELQIASLNN 400
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  365 ELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQEkgevlgdvlQLETLKQEAATLAANNTQLQARVETLEteqg 444
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA---------ELEELEEELEELQEELERLEEALEELR---- 467
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  445 QQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQ----AKEELEQASQAHGAR-LTAQVASLTSEL-----TTLNATI 514
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQARLDSLERLQENLEGfsegVKALLKNQSGLSGILgVLSELISVDEGYeaaieAALGGRL 547
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  515 QQ---QDQELADLKQQAKEEQAQLAQT----LQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQE------------ 575
Cdd:TIGR02168  548 QAvvvENLNAAKKAIAFLKQNELGRVTflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlv 627
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  576 VTRRDHAQQLAT------------------------AAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETR 631
Cdd:TIGR02168  628 VDDLDNALELAKklrpgyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  632 DSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKAT------------------EKERV 693
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerleeaeeelaeaeaEIEEL 787
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  694 AQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEaRLQQ 773
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE-ELEE 866
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  774 LGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQygamFQEQLMTLKEECEKARQELQEAK 853
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE----LREKLAQLELRLEGLEVRIDNLQ 942
                          730       740       750
                   ....*....|....*....|....*....|....*...
gi 1622865008  854 EKVAGIESHSELQISRQQNELVELHANLARALQQVQEK 891
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1078-1655 5.06e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 104.25  E-value: 5.06e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1078 KELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAagrteptgpKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASR 1157
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELEELEA---------ELEELEAELAELEAELEELRLELEELELELEEAQAEE 290
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1158 AERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSIL 1237
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1238 NRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTS 1317
Cdd:COG1196    371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1318 QAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRA 1397
Cdd:COG1196    451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1398 ---ELLRAQRELGELIPLRQKVAEQERTAQQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVE 1468
Cdd:COG1196    531 gveAAYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1469 LDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEEKQKLTAQVEQLEVFQREQT 1548
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1549 KQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN 1628
Cdd:COG1196    691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1622865008 1629 QELQE-----------------QLQSLEHLQKENKELRAEAERL 1655
Cdd:COG1196    771 RLEREiealgpvnllaieeyeeLEERYDFLSEQREDLEEARETL 814
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
1746-2016 2.38e-04

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.32  E-value: 2.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1746 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARSQA--PLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKL 1823
Cdd:PHA03307   192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIW 270
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1824 DVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARLSSPdyGNSALLSLPGYRP-----TTRSSARRSQAGVSSGAPPG 1898
Cdd:PHA03307   271 EASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPS--SPRASSSSSSSREsssssTSSSSESSRGAAVSPGPSPS 348
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1899 RNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlslgtitdeemktgdpqETLRRASMQ---PIQI 1975
Cdd:PHA03307   349 RS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARAAvagRARR 400
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1622865008 1976 AEGTGITTRQQRKRVSLEPHQGPGTPESKkatscfPRPMTP 2016
Cdd:PHA03307   401 RDATGRFPAGRPRPSPLDAGAASGAFYAR------YPLLTP 435
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
6-152 7.95e-58

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 196.64  E-value: 7.95e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008    6 TRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRLHGTEEGQQILQQPVPERLDFVCSFLQKNQKHPSSPECLVSAQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622865008   86 KVLEG--SELELAKMTMLLLYHSTMSSKSPrdWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLR 152
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
1870-1928 1.25e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 104.22  E-value: 1.25e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622865008 1870 LLSLPGYRPTTRSSARRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1928
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
560-1200 1.41e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 115.80  E-value: 1.41e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  560 LKQKEQQLKEVAEKQEVTRRdhAQQLATAAEEREASLRerdaalqqlealekekAAKLEILQQQLQVANETRDSAQTSVT 639
Cdd:COG1196    195 LGELERQLEPLERQAEKAER--YRELKEELKELEAELL----------------LLKLRELEAELEELEAELEELEAELE 256
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  640 QAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQkatEKERVAQEKDQLQEQLQALKESLKVTKGSLE 719
Cdd:COG1196    257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ---DIARLEERRRELEERLEELEEELAELEEELE 333
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  720 EEKRRAADALEEQQrcisELKAETRSLVEQHKQEQKELEEEKAGRkglearlqqlgEAHQAETEALRQELAEAIAAQRTA 799
Cdd:COG1196    334 ELEEELEELEEELE----EAEEELEEAEAELAEAEEALLEAEAEL-----------AEAEEELEELAEELLEALRAAAEL 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  800 ESECEQLVKEVAAWRERYEESQQEEAQYgamfQEQLMTLKEECEKARQELQEAKEKVAGIEShSELQISRQQNELVELHA 879
Cdd:COG1196    399 AAQLEELEEAEEALLERLERLEEELEEL----EEALAELEEEEEEEEEALEEAAEEEAELEE-EEEALLELLAELLEEAA 473
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  880 NLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDREPEwLEEQQGRQ 959
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAL-AAALQNIV 552
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  960 FCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALN 1039
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1040 EQRVEFA-TLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASgsgaqseaagrtept 1118
Cdd:COG1196    633 EAALRRAvTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE--------------- 697
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1119 gpKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTK 1198
Cdd:COG1196    698 --ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775

                   ..
gi 1622865008 1199 VQ 1200
Cdd:COG1196    776 IE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
549-1326 1.69e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 115.92  E-value: 1.69e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  549 LRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKA---AKLEILQQQLQ 625
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQeleEKLEELRLEVS 277
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  626 VANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEfqlQSEQQKATEKERVAQEKDQLQEQLQ 705
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE---SKLDELAEELAELEEKLEELKEELE 354
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  706 ALKESLKvtkgSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLgeahQAETEAL 785
Cdd:TIGR02168  355 SLEAELE----ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL----QQEIEEL 426
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  786 RQELAEAiaAQRTAESECEQLVKEVAAWRERYEEsqqeeaqygamFQEQLMTLKEECEKARQELQEAKEKVAGIESHSEL 865
Cdd:TIGR02168  427 LKKLEEA--ELKELQAELEELEEELEELQEELER-----------LEEALEELREELEEAEQALDAAERELAQLQARLDS 493
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  866 QISRQQNelvelHANLARALQQVQEKevrAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVK------ 939
Cdd:TIGR02168  494 LERLQEN-----LEGFSEGVKALLKN---QSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKkaiafl 565
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  940 EPARAGDREPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELE----RLRAAL------------MESQGQQQEERGQQE 1003
Cdd:TIGR02168  566 KQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVkfdpKLRKALsyllggvlvvddLDNALELAKKLRPGY 645
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1004 REV--------------------ARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKD 1063
Cdd:TIGR02168  646 RIVtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1064 QELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQA 1143
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL 805
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1144 DSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERK 1223
Cdd:TIGR02168  806 DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1224 NSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEK 1303
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIED 965
                          810       820
                   ....*....|....*....|...
gi 1622865008 1304 QrvaSENLRQELTSQAERAEELG 1326
Cdd:TIGR02168  966 D---EEEARRRLKRLENKIKELG 985
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
209-891 2.26e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 115.54  E-value: 2.26e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  209 LQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL-ALLNEKQAASPLEPRELEELRDKNES 287
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALaNEISRLEQQKQILRERLANLERQLEE 320
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  288 LTMRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEH---SRATQEWLEKQAQLEK 364
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetlRSKVAQLELQIASLNN 400
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  365 ELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQEkgevlgdvlQLETLKQEAATLAANNTQLQARVETLEteqg 444
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA---------ELEELEEELEELQEELERLEEALEELR---- 467
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  445 QQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQ----AKEELEQASQAHGAR-LTAQVASLTSEL-----TTLNATI 514
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQARLDSLERLQENLEGfsegVKALLKNQSGLSGILgVLSELISVDEGYeaaieAALGGRL 547
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  515 QQ---QDQELADLKQQAKEEQAQLAQT----LQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQE------------ 575
Cdd:TIGR02168  548 QAvvvENLNAAKKAIAFLKQNELGRVTflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlv 627
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  576 VTRRDHAQQLAT------------------------AAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETR 631
Cdd:TIGR02168  628 VDDLDNALELAKklrpgyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  632 DSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKAT------------------EKERV 693
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerleeaeeelaeaeaEIEEL 787
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  694 AQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEaRLQQ 773
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE-ELEE 866
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  774 LGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQygamFQEQLMTLKEECEKARQELQEAK 853
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE----LREKLAQLELRLEGLEVRIDNLQ 942
                          730       740       750
                   ....*....|....*....|....*....|....*...
gi 1622865008  854 EKVAGIESHSELQISRQQNELVELHANLARALQQVQEK 891
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1078-1655 5.06e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 104.25  E-value: 5.06e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1078 KELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAagrteptgpKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASR 1157
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELEELEA---------ELEELEAELAELEAELEELRLELEELELELEEAQAEE 290
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1158 AERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSIL 1237
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1238 NRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTS 1317
Cdd:COG1196    371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1318 QAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRA 1397
Cdd:COG1196    451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1398 ---ELLRAQRELGELIPLRQKVAEQERTAQQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVE 1468
Cdd:COG1196    531 gveAAYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1469 LDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEEKQKLTAQVEQLEVFQREQT 1548
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1549 KQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN 1628
Cdd:COG1196    691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1622865008 1629 QELQE-----------------QLQSLEHLQKENKELRAEAERL 1655
Cdd:COG1196    771 RLEREiealgpvnllaieeyeeLEERYDFLSEQREDLEEARETL 814
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
215-774 2.16e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 102.32  E-value: 2.16e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALlnekqaaspleprELEELRDKNESLTMRLHE 294
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  295 TLKQCQDLKTEKSQMDRKISQLLEEngdlsfkLREFASHLQQLQDALNELTEEHSRATQEWLEKQAQLEKELSTALQDkk 374
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEE-------LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA-- 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  375 cLEEKNEILQGKLSQLEEHLALLRenppqekgEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAER 454
Cdd:COG1196    371 -EAELAEAEEELEELAEELLEALR--------AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  455 DHFEEEKQQLSSLIANLQSSISNLSQAKEELEQAsQAHGARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQ 534
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALL-EAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  535 -------------LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEvAEKQEVTRRDHAQQLATAAEEREASLRERDA 601
Cdd:COG1196    521 glagavavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA-AKAGRATFLPLDKIRARAALAAALARGAIGA 599
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  602 ALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQ 681
Cdd:COG1196    600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  682 SEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEK 761
Cdd:COG1196    680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP 759
                          570
                   ....*....|...
gi 1622865008  762 AGRKGLEARLQQL 774
Cdd:COG1196    760 PDLEELERELERL 772
PTZ00121 PTZ00121
MAEBL; Provisional
517-1313 1.07e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 94.05  E-value: 1.07e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  517 QDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASL 596
Cdd:PTZ00121  1077 KDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEI 1156
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  597 -RERDAALQQLEALEKEKAAKLEILQQQLQV--ANETRDSAQTSVTQAQReKAELSQKVEELRaRVETACREQHEAQAQv 673
Cdd:PTZ00121  1157 aRKAEDARKAEEARKAEDAKKAEAARKAEEVrkAEELRKAEDARKAEAAR-KAEEERKAEEAR-KAEDAKKAEAVKKAE- 1233
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  674 aelEFQLQSEQQKATEKERVAQEKDQLQEQLQAlkeslkvtkgslEEEKRRAADALEEQQRCISELKAETRSLVEQHKQE 753
Cdd:PTZ00121  1234 ---EAKKDAEEAKKAEEERNNEEIRKFEEARMA------------HFARRQAAIKAEEARKADELKKAEEKKKADEAKKA 1298
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  754 QKELEEEKAGRKGLEAR----LQQLGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYE--ESQQEEAQY 827
Cdd:PTZ00121  1299 EEKKKADEAKKKAEEAKkadeAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaEKKKEEAKK 1378
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  828 GAmfqEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELVELHANLARALQQVQEKEVRAQKladdlstlQE 907
Cdd:PTZ00121  1379 KA---DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKK--------AD 1447
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  908 KMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDREPEWLEEQQGRQFCSTQAALQAME----REAEQMGNELER 983
Cdd:PTZ00121  1448 EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKadeaKKAEEAKKADEA 1527
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  984 LRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELE--MRLQNALNEQRVEFATLQEALAHALTEKEG 1061
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDknMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1062 KDQELVKLR--GLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQ 1139
Cdd:PTZ00121  1608 KAEEAKKAEeaKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1140 QEQADSLERslEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQE 1219
Cdd:PTZ00121  1688 KKAAEALKK--EAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKE 1765
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1220 AERKNSLISSLEEEVSilnrqvleKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLRE 1299
Cdd:PTZ00121  1766 EEKKAEEIRKEKEAVI--------EEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVAD 1837
                          810
                   ....*....|....
gi 1622865008 1300 EAEKQRVASENLRQ 1313
Cdd:PTZ00121  1838 SKNMQLEEADAFEK 1851
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1033-1731 4.33e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 4.33e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1033 RLQNALNEQRVEFATLQEALAHALTEKEGKDQelvkLRGLEAA-QIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEA 1111
Cdd:TIGR02168  190 RLEDILNELERQLKSLERQAEKAERYKELKAE----LRELELAlLVLRLEELREELEELQEELKEAEEELEELTAELQEL 265
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1112 AGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRE 1191
Cdd:TIGR02168  266 EEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK 345
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1192 LAALRTKVQDHSKAEDEWKAQvargRQEAERKNsliSSLEEEVSILNRQVLEKEGESKEL-KRLVMAESEKSQkLEDRLR 1270
Cdd:TIGR02168  346 LEELKEELESLEAELEELEAE----LEELESRL---EELEEQLETLRSKVAQLELQIASLnNEIERLEARLER-LEDRRE 417
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1271 LLQAETASNSARAAE-RSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQ---ALSTL 1346
Cdd:TIGR02168  418 RLQQEIEELLKKLEEaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQArldSLERL 497
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1347 QLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRhREELEQSKQAAGGLRAELL--------------RAQRELG----- 1407
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSGLSGILGVLSELISV-DEGYEAAIEAALGGRLQAVvvenlnaakkaiafLKQNELGrvtfl 576
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1408 --------ELIPLRQKVAEQERTAQQLRAEKASYAEQLSM--------------LKKAHGLLAEENRGL----------- 1454
Cdd:TIGR02168  577 pldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvddLDNALELAKKLRPGYrivtldgdlvr 656
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1455 --------GERANLGRQFLEVELDQAREKyVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEER--- 1523
Cdd:TIGR02168  657 pggvitggSAKTNSSILERRREIEELEEK-IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkdl 735
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1524 QRFQEEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQK 1603
Cdd:TIGR02168  736 ARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1604 EQAAEHYKLQMEKAKTHYDAKKqqnqelqeqlQSLEHLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSL 1683
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATE----------RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1622865008 1684 EAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEE 1731
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
PTZ00121 PTZ00121
MAEBL; Provisional
1012-1670 6.97e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 87.89  E-value: 6.97e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1012 ERGRAQADLALEKAAKAELEMRlqNALNEQRVEFATLQEALAHALTEKEGKDQELVKLrGLEAAQIKELEELRQTMKQLK 1091
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKK--KAEDARKAEEARKAEDARKAEEARKAEDAKRVEI-ARKAEDARKAEEARKAEDAKK 1177
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1092 EQLAKKEKE-HASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQ 1170
Cdd:PTZ00121  1178 AEAARKAEEvRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKF 1257
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1171 LEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEevsiLNRQVLEKEGESKE 1250
Cdd:PTZ00121  1258 EEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADE----AKKKAEEAKKKADA 1333
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1251 LKRLVMAESEKSQ--KLEDRLRLLQAETASNSARAAE-RSSALREEVQSLREEAEKQRVASENLR--QELTSQAERAEEL 1325
Cdd:PTZ00121  1334 AKKKAEEAKKAAEaaKAEAEAAADEAEAAEEKAEAAEkKKEEAKKKADAAKKKAEEKKKADEAKKkaEEDKKKADELKKA 1413
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1326 GQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQ-R 1404
Cdd:PTZ00121  1414 AAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKaE 1493
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1405 ELGELIPLRQKVAEQERTAQQLR-AEKASYAEQLSMLKKAHGllAEENRGLGERANLGRQFLEVELDQAREKYVQE---L 1480
Cdd:PTZ00121  1494 EAKKKADEAKKAAEAKKKADEAKkAEEAKKADEAKKAEEAKK--ADEAKKAEEKKKADELKKAEELKKAEEKKKAEeakK 1571
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1481 AAVRADAETRLAEVQREAQStARELEVMTAKYEGAKVKVlEERQRFQEEKQK---------LTAQVEQLEVFQREQTKQV 1551
Cdd:PTZ00121  1572 AEEDKNMALRKAEEAKKAEE-ARIEEVMKLYEEEKKMKA-EEAKKAEEAKIKaeelkkaeeEKKKVEQLKKKEAEEKKKA 1649
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1552 EELRKkladSDQASKVQQQKLKavqaqggesqQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQEL 1631
Cdd:PTZ00121  1650 EELKK----AEEENKIKAAEEA----------KKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK 1715
                          650       660       670
                   ....*....|....*....|....*....|....*....
gi 1622865008 1632 QEQlqslEHLQKENKELRAEAERLGHELQQAGLKTKEAE 1670
Cdd:PTZ00121  1716 KKA----EELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
223-900 8.68e-15

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 80.65  E-value: 8.68e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  223 LADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDrlALLNEKQAASPLEPRELEELRDKNESLTMRLHETLKQCQdl 302
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQ--ETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDR-- 321
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  303 ktekSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEWLEKQAQLEKELSTALQDkkcleeknei 382
Cdd:pfam12128  322 ----SELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQ---------- 387
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  383 LQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNtqlqARVETLETEQGQQEAKLLAERDHFEEEkq 462
Cdd:pfam12128  388 NNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLE----FNEEEYRLKSRLGELKLRLNQATATPE-- 461
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  463 qlssLIANLQSSISNLSQAKEELEQAsqahgarlTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQ 542
Cdd:pfam12128  462 ----LLLQLENFDERIERAREEQEAA--------NAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQL 529
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  543 EQASQGLRHqveQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEAleKEKAAKLEILQQ 622
Cdd:pfam12128  530 FPQAGTLLH---FLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDV--PEWAASEEELRE 604
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  623 QLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKerVAQEKDQLQE 702
Cdd:pfam12128  605 RLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKA--LAERKDSANE 682
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  703 QLQALKESLKVTKGSLEeekrraaDALEEQQRCISELKaetrslVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQAET 782
Cdd:pfam12128  683 RLNSLEAQLKQLDKKHQ-------AWLEEQKEQKREAR------TEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAEL 749
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  783 EALRQELAEAIAAQRTAE---SECEQLVKEVAAWRERYEESQQEEAQYGAMFQEQLMT----LKEECEKARQELQEAKEK 855
Cdd:pfam12128  750 KALETWYKRDLASLGVDPdviAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQrrprLATQLSNIERAISELQQQ 829
                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1622865008  856 VAGIESHSELQISRQQNELVELHANLARALQQVQEKEVRAQKLAD 900
Cdd:pfam12128  830 LARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
PTZ00121 PTZ00121
MAEBL; Provisional
215-856 1.06e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.49  E-value: 1.06e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEP-------RELEELRDKNES 287
Cdd:PTZ00121  1144 EARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAarkaeeeRKAEEARKAEDA 1223
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  288 LTM----RLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDAlneltEEHSRATQEWLEKQAQLE 363
Cdd:PTZ00121  1224 KKAeavkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-----DELKKAEEKKKADEAKKA 1298
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  364 KELSTALQDKKCLEEKNEILQGKLSQLEehlALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQ 443
Cdd:PTZ00121  1299 EEKKKADEAKKKAEEAKKADEAKKKAEE---AKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE 1375
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  444 GQQEAKLLAERdhfEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTlNATIQQQDQELAD 523
Cdd:PTZ00121  1376 AKKKADAAKKK---AEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK-KAEEAKKADEAKK 1451
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  524 LKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAE--KQEVTRRDHAQQLATAAEEREA-SLRERD 600
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADeaKKAAEAKKKADEAKKAEEAKKAdEAKKAE 1531
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  601 AALQQLEALEKEKAAKLEILQ--QQLQVANETRDSAQTSVTQAQRE----KAELSQKVEELRArvetacreqhEAQAQVA 674
Cdd:PTZ00121  1532 EAKKADEAKKAEEKKKADELKkaEELKKAEEKKKAEEAKKAEEDKNmalrKAEEAKKAEEARI----------EEVMKLY 1601
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  675 ELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKgslEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQ 754
Cdd:PTZ00121  1602 EEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE---AEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE 1678
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  755 KELEEEKAGRKGLEARLQQLGEAHQAEtEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQ-EEAQYGAMFQE 833
Cdd:PTZ00121  1679 EAKKAEEDEKKAAEALKKEAEEAKKAE-ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKaEEAKKDEEEKK 1757
                          650       660
                   ....*....|....*....|...
gi 1622865008  834 QLMTLKEECEKARQELQEAKEKV 856
Cdd:PTZ00121  1758 KIAHLKKEEEKKAEEIRKEKEAV 1780
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
406-711 1.91e-11

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 69.86  E-value: 1.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  406 GEVLGDVLQLETLKQEAATLAANNTQLQARVETLeteqgQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKeeL 485
Cdd:NF012221  1528 GYILDNVVATSESSQQADAVSKHAKQDDAAQNAL-----ADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNA--L 1600
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  486 EQASQAHGARLTAQVASLTSELTTLNATIQQ---QDQELADLKQQAKEEQAQLAQTLQQQEQASQGL--RHQVEQLSSSL 560
Cdd:NF012221  1601 ETNGQAQRDAILEESRAVTKELTTLAQGLDAldsQATYAGESGDQWRNPFAGGLLDRVQEQLDDAKKisGKQLADAKQRH 1680
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  561 KQKEQQLKEVAEKQE--VTRRDHAQQLATAAEER---EASLRERDAALQQLEALEKEKAAKLEIlqQQLQVANETRDSAQ 635
Cdd:NF012221  1681 VDNQQKVKDAVAKSEagVAQGEQNQANAEQDIDDakaDAEKRKDDALAKQNEAQQAESDANAAA--NDAQSRGEQDASAA 1758
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  636 TSVT-QAQREKAELSQ----KVEELRARVETACREQHEAQAqVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKES 710
Cdd:NF012221  1759 ENKAnQAQADAKGAKQdesdKPNRQGAAGSGLSGKAYSVEG-VAEPGSHINPDSPAAADGRFSEGLTEQEQEALEGATNA 1837

                   .
gi 1622865008  711 L 711
Cdd:NF012221  1838 V 1838
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
1219-1571 3.25e-10

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 65.53  E-value: 3.25e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1219 EAERKNSLISSLEEEVSILNRQVLEKeGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLR 1298
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEK-FEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAME 345
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1299 EEAEKQRVASENLRQELtsQAERAEELGQELKAWQEkffqkeqaLSTLQLEHTSTQALVSELLPAkhlcqqlqaeqaAAE 1378
Cdd:pfam17380  346 RERELERIRQEERKREL--ERIRQEEIAMEISRMRE--------LERLQMERQQKNERVRQELEA------------ARK 403
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1379 KRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML-------KKAHGLLAEEN 1451
Cdd:pfam17380  404 VKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLrqqeeerKRKKLELEKEK 483
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1452 RGLGERANLGRQFLEVELDQAREKYVQElaavraDAETRLAEVQREAQSTA--RELEVMTAKYEGAKVKVLEERQRFQEE 1529
Cdd:pfam17380  484 RDRKRAEEQRRKILEKELEERKQAMIEE------ERKRKLLEKEMEERQKAiyEEERRREAEEERRKQQEMEERRRIQEQ 557
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1622865008 1530 KQKLTAQVEQLEVFQREQ--TKQVEELRKKLADSDQASKVQQQK 1571
Cdd:pfam17380  558 MRKATEERSRLEAMERERemMRQIVESEKARAEYEATTPITTIK 601
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
242-750 1.13e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 63.98  E-value: 1.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  242 KLLTEKDAQIAMMQQRI----DRL-ALLNEKQAASPLEPRE----LEELRDKNESLTMRLHETLKQCQDLKTE-KSQMDR 311
Cdd:pfam15921  224 KILRELDTEISYLKGRIfpveDQLeALKSESQNKIELLLQQhqdrIEQLISEHEVEITGLTEKASSARSQANSiQSQLEI 303
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  312 KISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEwLEKQAQL-EKELSTAL-------QDKKCLEEKNEIL 383
Cdd:pfam15921  304 IQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEE-LEKQLVLaNSELTEARterdqfsQESGNLDDQLQKL 382
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  384 QGKLSQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETE-QGQQEAKLLAERDHfEEEKQ 462
Cdd:pfam15921  383 LADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMAAIQGK-NESLE 461
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  463 QLSSLIANLQSSISNLSQAKEELE------QASQAHGARLTAQ-------VASLTSELTTLNATIQQQDQELADLK---- 525
Cdd:pfam15921  462 KVSSLTAQLESTKEMLRKVVEELTakkmtlESSERTVSDLTASlqekeraIEATNAEITKLRSRVDLKLQELQHLKnegd 541
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  526 --QQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKE------QQLKEVAEKQEVTRRDHAQQLATAAEEREASLR 597
Cdd:pfam15921  542 hlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGrtagamQVEKAQLEKEINDRRLELQEFKILKDKKDAKIR 621
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  598 ERDAALQQLEaLEKEKA--AKLEILQQQLQVANEtRDSAQTSVTQAQREKAELSQKVEELRARVETacrEQHEAQAQVAE 675
Cdd:pfam15921  622 ELEARVSDLE-LEKVKLvnAGSERLRAVKDIKQE-RDQLLNEVKTSRNELNSLSEDYEVLKRNFRN---KSEEMETTTNK 696
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622865008  676 LEFQLQSEQQKatekerVAQEKDQLQEQLQALKESLKVTKGSLEE--EKRRAADALEEQQRCISElkAETRSLVEQH 750
Cdd:pfam15921  697 LKMQLKSAQSE------LEQTRNTLKSMEGSDGHAMKVAMGMQKQitAKRGQIDALQSKIQFLEE--AMTNANKEKH 765
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
1746-2016 2.38e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.32  E-value: 2.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1746 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARSQA--PLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKL 1823
Cdd:PHA03307   192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIW 270
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1824 DVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARLSSPdyGNSALLSLPGYRP-----TTRSSARRSQAGVSSGAPPG 1898
Cdd:PHA03307   271 EASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPS--SPRASSSSSSSREsssssTSSSSESSRGAAVSPGPSPS 348
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1899 RNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlslgtitdeemktgdpqETLRRASMQ---PIQI 1975
Cdd:PHA03307   349 RS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARAAvagRARR 400
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1622865008 1976 AEGTGITTRQQRKRVSLEPHQGPGTPESKkatscfPRPMTP 2016
Cdd:PHA03307   401 RDATGRFPAGRPRPSPLDAGAASGAFYAR------YPLLTP 435
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
6-152 7.95e-58

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 196.64  E-value: 7.95e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008    6 TRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRLHGTEEGQQILQQPVPERLDFVCSFLQKNQKHPSSPECLVSAQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622865008   86 KVLEG--SELELAKMTMLLLYHSTMSSKSPrdWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLR 152
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
1870-1928 1.25e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 104.22  E-value: 1.25e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622865008 1870 LLSLPGYRPTTRSSARRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1928
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
560-1200 1.41e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 115.80  E-value: 1.41e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  560 LKQKEQQLKEVAEKQEVTRRdhAQQLATAAEEREASLRerdaalqqlealekekAAKLEILQQQLQVANETRDSAQTSVT 639
Cdd:COG1196    195 LGELERQLEPLERQAEKAER--YRELKEELKELEAELL----------------LLKLRELEAELEELEAELEELEAELE 256
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  640 QAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQkatEKERVAQEKDQLQEQLQALKESLKVTKGSLE 719
Cdd:COG1196    257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ---DIARLEERRRELEERLEELEEELAELEEELE 333
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  720 EEKRRAADALEEQQrcisELKAETRSLVEQHKQEQKELEEEKAGRkglearlqqlgEAHQAETEALRQELAEAIAAQRTA 799
Cdd:COG1196    334 ELEEELEELEEELE----EAEEELEEAEAELAEAEEALLEAEAEL-----------AEAEEELEELAEELLEALRAAAEL 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  800 ESECEQLVKEVAAWRERYEESQQEEAQYgamfQEQLMTLKEECEKARQELQEAKEKVAGIEShSELQISRQQNELVELHA 879
Cdd:COG1196    399 AAQLEELEEAEEALLERLERLEEELEEL----EEALAELEEEEEEEEEALEEAAEEEAELEE-EEEALLELLAELLEEAA 473
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  880 NLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDREPEwLEEQQGRQ 959
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAL-AAALQNIV 552
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  960 FCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALN 1039
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1040 EQRVEFA-TLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASgsgaqseaagrtept 1118
Cdd:COG1196    633 EAALRRAvTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE--------------- 697
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1119 gpKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTK 1198
Cdd:COG1196    698 --ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775

                   ..
gi 1622865008 1199 VQ 1200
Cdd:COG1196    776 IE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
549-1326 1.69e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 115.92  E-value: 1.69e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  549 LRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKA---AKLEILQQQLQ 625
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQeleEKLEELRLEVS 277
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  626 VANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEfqlQSEQQKATEKERVAQEKDQLQEQLQ 705
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE---SKLDELAEELAELEEKLEELKEELE 354
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  706 ALKESLKvtkgSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLgeahQAETEAL 785
Cdd:TIGR02168  355 SLEAELE----ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL----QQEIEEL 426
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  786 RQELAEAiaAQRTAESECEQLVKEVAAWRERYEEsqqeeaqygamFQEQLMTLKEECEKARQELQEAKEKVAGIESHSEL 865
Cdd:TIGR02168  427 LKKLEEA--ELKELQAELEELEEELEELQEELER-----------LEEALEELREELEEAEQALDAAERELAQLQARLDS 493
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  866 QISRQQNelvelHANLARALQQVQEKevrAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVK------ 939
Cdd:TIGR02168  494 LERLQEN-----LEGFSEGVKALLKN---QSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKkaiafl 565
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  940 EPARAGDREPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELE----RLRAAL------------MESQGQQQEERGQQE 1003
Cdd:TIGR02168  566 KQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVkfdpKLRKALsyllggvlvvddLDNALELAKKLRPGY 645
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1004 REV--------------------ARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKD 1063
Cdd:TIGR02168  646 RIVtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1064 QELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQA 1143
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL 805
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1144 DSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERK 1223
Cdd:TIGR02168  806 DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1224 NSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEK 1303
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIED 965
                          810       820
                   ....*....|....*....|...
gi 1622865008 1304 QrvaSENLRQELTSQAERAEELG 1326
Cdd:TIGR02168  966 D---EEEARRRLKRLENKIKELG 985
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
209-891 2.26e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 115.54  E-value: 2.26e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  209 LQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL-ALLNEKQAASPLEPRELEELRDKNES 287
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALaNEISRLEQQKQILRERLANLERQLEE 320
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  288 LTMRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEH---SRATQEWLEKQAQLEK 364
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetlRSKVAQLELQIASLNN 400
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  365 ELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQEkgevlgdvlQLETLKQEAATLAANNTQLQARVETLEteqg 444
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA---------ELEELEEELEELQEELERLEEALEELR---- 467
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  445 QQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQ----AKEELEQASQAHGAR-LTAQVASLTSEL-----TTLNATI 514
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQARLDSLERLQENLEGfsegVKALLKNQSGLSGILgVLSELISVDEGYeaaieAALGGRL 547
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  515 QQ---QDQELADLKQQAKEEQAQLAQT----LQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQE------------ 575
Cdd:TIGR02168  548 QAvvvENLNAAKKAIAFLKQNELGRVTflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlv 627
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  576 VTRRDHAQQLAT------------------------AAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETR 631
Cdd:TIGR02168  628 VDDLDNALELAKklrpgyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  632 DSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKAT------------------EKERV 693
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerleeaeeelaeaeaEIEEL 787
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  694 AQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEaRLQQ 773
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE-ELEE 866
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  774 LGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQygamFQEQLMTLKEECEKARQELQEAK 853
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE----LREKLAQLELRLEGLEVRIDNLQ 942
                          730       740       750
                   ....*....|....*....|....*....|....*...
gi 1622865008  854 EKVAGIESHSELQISRQQNELVELHANLARALQQVQEK 891
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
563-1331 3.59e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 114.77  E-value: 3.59e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  563 KEQQLKEVAEKQEVTRRDHAQQLATAAEEREASL----RERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSV 638
Cdd:TIGR02168  169 KYKERRKETERKLERTRENLDRLEDILNELERQLksleRQAEKAERYKELKAELRELELALLVLRLEELREELEELQEEL 248
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  639 TQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQkatEKERVAQEKDQLQEQLQALKESLKVTKGSL 718
Cdd:TIGR02168  249 KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN---EISRLEQQKQILRERLANLERQLEELEAQL 325
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  719 EEEKRRaadaLEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLgeahQAETEALRQELAEAIAAQRT 798
Cdd:TIGR02168  326 EELESK----LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL----EEQLETLRSKVAQLELQIAS 397
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  799 AESECEQLVKEVAAWRERYEESQQEEAQYGAMFQE-QLMTLKEECEKARQELQEAKEKVAGIEShselQISRQQNELVEL 877
Cdd:TIGR02168  398 LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaELKELQAELEELEEELEELQEELERLEE----ALEELREELEEA 473
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  878 HANLARALQQVQEKEVRA---QKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASR-ELVKEPARAGDREPEWLE 953
Cdd:TIGR02168  474 EQALDAAERELAQLQARLdslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGyEAAIEAALGGRLQAVVVE 553
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  954 eqqgrqfcSTQAALQAMEREAEQmgnelERLRAALMEsqGQQQEERGQQEREVARLTQERGRAQADLALEKAAkAELEMR 1033
Cdd:TIGR02168  554 --------NLNAAKKAIAFLKQN-----ELGRVTFLP--LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFD-PKLRKA 617
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1034 LQNALNEQRVeFATLQEALAHALTEKEG-----KDQELVKLRGLEA-----------AQIKELEELRQTMKQLKEQLAKK 1097
Cdd:TIGR02168  618 LSYLLGGVLV-VDDLDNALELAKKLRPGyrivtLDGDLVRPGGVITggsaktnssilERRREIEELEEKIEELEEKIAEL 696
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1098 EKEHASGSGAQSE-------AAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQ 1170
Cdd:TIGR02168  697 EKALAELRKELEEleeeleqLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE 776
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1171 LEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKE 1250
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1251 LKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLReEAEKQRVASENLRQELTSQAERAEELGQELK 1330
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR-ELESKRSELRRELEELREKLAQLELRLEGLE 935

                   .
gi 1622865008 1331 A 1331
Cdd:TIGR02168  936 V 936
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
471-1095 2.66e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.49  E-value: 2.66e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  471 LQSSISNLSQAKEELEQASQAHgARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEeqaqlaqtlqqqeqasqgLR 550
Cdd:COG1196    227 AELLLLKLRELEAELEELEAEL-EELEAELEELEAELAELEAELEELRLELEELELELEE------------------AQ 287
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  551 HQVEQLSSSLKQKEQQLKEVAEKQevtrrdhaQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANET 630
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERR--------RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE 359
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  631 RDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEfqlQSEQQKATEKERVAQEKDQLQEQLQALKES 710
Cdd:COG1196    360 LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE---EAEEALLERLERLEEELEELEEALAELEEE 436
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  711 LKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQAETEALRQELA 790
Cdd:COG1196    437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  791 EAIAAQrtaesecEQLVKEVAAWRERYEESQQEEAqyGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQ 870
Cdd:COG1196    517 AGLRGL-------AGAVAVLIGVEAAYEAALEAAL--AAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAA 587
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  871 QNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAgdrepe 950
Cdd:COG1196    588 LAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS------ 661
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  951 wleeqqgrqfcSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAEL 1030
Cdd:COG1196    662 -----------LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622865008 1031 EMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELVKLRGLEA----------AQIKELEELRQTMKQLKEQLA 1095
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEReiealgpvnlLAIEEYEELEERYDFLSEQRE 805
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
219-937 2.89e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.61  E-value: 2.89e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  219 LKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALlnekqaaspleprELEELRDKNESLTMRLHETLKQ 298
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL-------------EVSELEEEIEELQKELYALANE 296
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  299 CQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEhsraTQEWLEKQAQLEKELSTALQDKKCLEE 378
Cdd:TIGR02168  297 ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK----LEELKEELESLEAELEELEAELEELES 372
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  379 KNEILQGKLSQLEEHLALLRENPPQEKGevlgdvlQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERdhFE 458
Cdd:TIGR02168  373 RLEELEEQLETLRSKVAQLELQIASLNN-------EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE--LE 443
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  459 EEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGArLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQT 538
Cdd:TIGR02168  444 ELEEELEELQEELERLEEALEELREELEEAEQALDA-AERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIL 522
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  539 LQQQEQAS--QGLRHQVEQ-LSSSL-----KQKEQQLKEVA--EKQEVTRR-----DHAQQLATAAEEREASLRERDAAL 603
Cdd:TIGR02168  523 GVLSELISvdEGYEAAIEAaLGGRLqavvvENLNAAKKAIAflKQNELGRVtflplDSIKGTEIQGNDREILKNIEGFLG 602
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  604 QQLEALEKEKAAKLEI------------LQQQLQVANETRD------------SAQTSVTQAQREKA----ELSQKVEEL 655
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALsyllggvlvvddLDNALELAKKLRPgyrivtldgdlvRPGGVITGGSAKTNssilERRREIEEL 682
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  656 RARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLkvtkgslEEEKRRAADALEEQQRC 735
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL-------EAEVEQLEERIAQLSKE 755
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  736 ISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQAETEALRQelaeaiaaqrtAESECEQLVKEVAAWRE 815
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE-----------LRAELTLLNEEAANLRE 824
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  816 RYEESQQEeaqygamfqeqlmtlKEECEKARQELQEAKEKVAGIESHSELQISRQQNELVELHANLARALQQVQEKEVRA 895
Cdd:TIGR02168  825 RLESLERR---------------IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1622865008  896 QKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASREL 937
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1078-1655 5.06e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 104.25  E-value: 5.06e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1078 KELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAagrteptgpKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASR 1157
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELEELEA---------ELEELEAELAELEAELEELRLELEELELELEEAQAEE 290
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1158 AERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSIL 1237
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1238 NRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTS 1317
Cdd:COG1196    371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1318 QAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRA 1397
Cdd:COG1196    451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1398 ---ELLRAQRELGELIPLRQKVAEQERTAQQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVE 1468
Cdd:COG1196    531 gveAAYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1469 LDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEEKQKLTAQVEQLEVFQREQT 1548
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1549 KQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN 1628
Cdd:COG1196    691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1622865008 1629 QELQE-----------------QLQSLEHLQKENKELRAEAERL 1655
Cdd:COG1196    771 RLEREiealgpvnllaieeyeeLEERYDFLSEQREDLEEARETL 814
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
458-1275 1.19e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 103.21  E-value: 1.19e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  458 EEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHgARLTAQVASLTSELTTLNATIQQQDQELADLKQqakeeqaqlaq 537
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEEL-EELTAELQELEEKLEELRLEVSELEEEIEELQK----------- 288
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  538 TLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVT--RRDHAQQLATAAEEREASLRERdaaLQQLEALEKEKAA 615
Cdd:TIGR02168  289 ELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELesKLDELAEELAELEEKLEELKEE---LESLEAELEELEA 365
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  616 KLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKAT--EKERV 693
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELqaELEEL 445
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  694 AQEKDQLQEQLQALKESLKVTKGSLEEeKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQ 773
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEE-AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV 524
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  774 LGEAHQAEtEALRQELAEAIAAQRTAeseceQLVKEVAAWRERYEeSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAK 853
Cdd:TIGR02168  525 LSELISVD-EGYEAAIEAALGGRLQA-----VVVENLNAAKKAIA-FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNI 597
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  854 EKVAGIeshselqISRQQNELVELHANLARALQQVqekevraqKLADDLSTLQEKmaatSKEVARLETLVRKAGEQ---- 929
Cdd:TIGR02168  598 EGFLGV-------AKDLVKFDPKLRKALSYLLGGV--------LVVDDLDNALEL----AKKLRPGYRIVTLDGDLvrpg 658
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  930 ----QETASRELVKEPARAGDREPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMEsqgqQQEERGQQERE 1005
Cdd:TIGR02168  659 gvitGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE----LSRQISALRKD 734
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1006 VARLTQERGRAQADLALEKAAKAELEmrlqnalneqrvefatlqealahalTEKEGKDQELVKLRGLEAAQIKELEELRQ 1085
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELE-------------------------AEIEELEERLEEAEEELAEAEAEIEELEA 789
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1086 TMKQLKEQLAKKEKEHASGSGAQSEaagrtepTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALE 1165
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTL-------LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1166 TLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKE 1245
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942
                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1622865008 1246 GESKELKRLVMAESEK--------SQKLEDRLRLLQAE 1275
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEAlenkieddEEEARRRLKRLENK 980
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
215-774 2.16e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 102.32  E-value: 2.16e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALlnekqaaspleprELEELRDKNESLTMRLHE 294
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  295 TLKQCQDLKTEKSQMDRKISQLLEEngdlsfkLREFASHLQQLQDALNELTEEHSRATQEWLEKQAQLEKELSTALQDkk 374
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEE-------LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA-- 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  375 cLEEKNEILQGKLSQLEEHLALLRenppqekgEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAER 454
Cdd:COG1196    371 -EAELAEAEEELEELAEELLEALR--------AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  455 DHFEEEKQQLSSLIANLQSSISNLSQAKEELEQAsQAHGARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQ 534
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALL-EAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  535 -------------LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEvAEKQEVTRRDHAQQLATAAEEREASLRERDA 601
Cdd:COG1196    521 glagavavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA-AKAGRATFLPLDKIRARAALAAALARGAIGA 599
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  602 ALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQ 681
Cdd:COG1196    600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  682 SEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEK 761
Cdd:COG1196    680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP 759
                          570
                   ....*....|...
gi 1622865008  762 AGRKGLEARLQQL 774
Cdd:COG1196    760 PDLEELERELERL 772
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1075-1656 2.39e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.94  E-value: 2.39e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1075 AQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERsleaER 1154
Cdd:COG1196    229 LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ----DI 304
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1155 ASRAERDSALETLQGQLEEKARELghsQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEV 1234
Cdd:COG1196    305 ARLEERRRELEERLEELEEELAEL---EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1235 SILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEKQrvasENLRQE 1314
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE----AELEEE 457
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1315 LTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGG 1394
Cdd:COG1196    458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1395 LRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASyAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQARE 1474
Cdd:COG1196    538 AALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT-FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1475 KYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEEKQKLTAQVEQLEVFQREQTKQVEEL 1554
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1555 RKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEhyklqmekakthydakkqQNQELQEQ 1634
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE------------------EALEELPE 758
                          570       580
                   ....*....|....*....|..
gi 1622865008 1635 LQSLEHLQKENKELRAEAERLG 1656
Cdd:COG1196    759 PPDLEELERELERLEREIEALG 780
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
525-1365 3.19e-20

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 98.60  E-value: 3.19e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  525 KQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQ 604
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEE 251
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  605 QLEALEK---EKAAKLEILQQQL-QVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQL 680
Cdd:TIGR02169  252 ELEKLTEeisELEKRLEEIEQLLeELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI 331
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  681 QSEQQKATEKER----VAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQ---QRCISELKAETRSLVEQHKQE 753
Cdd:TIGR02169  332 DKLLAEIEELEReieeERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELkdyREKLEKLKREINELKRELDRL 411
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  754 QKELEEEKAGRKGLEARLQQLgEAHQAETEALRQELAEAIAAQrtaESECEQLVKEVAAWRERYEESQQEEAQYgamfQE 833
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGI-EAKINELEEEKEDKALEIKKQ---EWKLEQLAADLSKYEQELYDLKEEYDRV----EK 483
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  834 QLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELvelhaNLARALQQVQEK-----EVRAQKLADDLSTLQEK 908
Cdd:TIGR02169  484 ELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVH-----GTVAQLGSVGERyataiEVAAGNRLNNVVVEDDA 558
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  909 MAATSKEVARletlVRKAGE------QQETASRELVKEPARAG---------DREPEWleEQQGRQFCSTQAALQAMERE 973
Cdd:TIGR02169  559 VAKEAIELLK----RRKAGRatflplNKMRDERRDLSILSEDGvigfavdlvEFDPKY--EPAFKYVFGDTLVVEDIEAA 632
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  974 AEQMGN-ELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEmRLQNALNEQRVEFATLQEAL 1052
Cdd:TIGR02169  633 RRLMGKyRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELS-SLQSELRRIENRLDELSQEL 711
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1053 AHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEhasgsgaQSEAAGRTEPTGPKLEALRAEVSKL 1132
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE-------LKELEARIEELEEDLHKLEEALNDL 784
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1133 EQQCQQQQEqaDSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQ 1212
Cdd:TIGR02169  785 EARLSHSRI--PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGK 862
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1213 VARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALRE 1292
Cdd:TIGR02169  863 KEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942
                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622865008 1293 EVQSLREEAEKQRVASEnlRQELTSQAERAEELG----QELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKH 1365
Cdd:TIGR02169  943 DEEIPEEELSLEDVQAE--LQRVEEEIRALEPVNmlaiQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKR 1017
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
964-1541 1.02e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.93  E-value: 1.02e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  964 QAALQAMEREAEQMGNELERLRAALmesqgqqqeerGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRV 1043
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAEL-----------AELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1044 EfatlQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLE 1123
Cdd:COG1196    307 L----EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1124 ALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHS 1203
Cdd:COG1196    383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1204 KAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEK---SQKLEDRLRLLQAETASNS 1280
Cdd:COG1196    463 ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglaGAVAVLIGVEAAYEAALEA 542
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1281 ARAAERSSALREEVQSLREEAE--KQRVASENLRQELTSQAERAEELGQELKAWQEKFF-------QKEQALSTLQLEHT 1351
Cdd:COG1196    543 ALAAALQNIVVEDDEVAAAAIEylKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdlvasdlREADARYYVLGDTL 622
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1352 STQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKA 1431
Cdd:COG1196    623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1432 SYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMtak 1511
Cdd:COG1196    703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL--- 779
                          570       580       590
                   ....*....|....*....|....*....|.
gi 1622865008 1512 yeGA-KVKVLEERQRFQEEKQKLTAQVEQLE 1541
Cdd:COG1196    780 --GPvNLLAIEEYEELEERYDFLSEQREDLE 808
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
783-1599 3.17e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.12  E-value: 3.17e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  783 EALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQygamfqeqlmtLKEECEKARQELQEAKEKVAGIESh 862
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSE-----------LEEEIEELQKELYALANEISRLEQ- 302
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  863 selQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRelvkepa 942
Cdd:TIGR02168  303 ---QKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELES------- 372
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  943 RAGDREPEWLEEqqgrqfcstQAALQAMEREAEQMGNELERLRAALmesqgqqqeerGQQEREVARLTQErgRAQADLAL 1022
Cdd:TIGR02168  373 RLEELEEQLETL---------RSKVAQLELQIASLNNEIERLEARL-----------ERLEDRRERLQQE--IEELLKKL 430
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1023 EKAAKAELEMRlqnaLNEQRVEFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHA 1102
Cdd:TIGR02168  431 EEAELKELQAE----LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSE 506
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1103 SGSGAQSEAAGRTEPTGPKLE--------------ALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETlq 1168
Cdd:TIGR02168  507 GVKALLKNQSGLSGILGVLSElisvdegyeaaieaALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGT-- 584
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1169 gQLEEKARELGHSQSALASVQRELAALRTKVQdhsKAEDEWKAQV--------ARGRQEAERKNSLISSLEEEVsILNRQ 1240
Cdd:TIGR02168  585 -EIQGNDREILKNIEGFLGVAKDLVKFDPKLR---KALSYLLGGVlvvddldnALELAKKLRPGYRIVTLDGDL-VRPGG 659
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1241 VLEKEGESKELKRLvmaesEKSQKLEDrLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE 1320
Cdd:TIGR02168  660 VITGGSAKTNSSIL-----ERRREIEE-LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRK 733
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1321 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELL 1400
Cdd:TIGR02168  734 DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1401 RAQRELGELIP----LRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHG----LLAEENRGLGERANLgRQFLEVELDQA 1472
Cdd:TIGR02168  814 LLNEEAANLRErlesLERRIAATERRLEDLEEQIEELSEDIESLAAEIEeleeLIEELESELEALLNE-RASLEEALALL 892
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1473 REKYvQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEEkQKLTAQVeqLEVFQREQTKQVE 1552
Cdd:TIGR02168  893 RSEL-EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE-YSLTLEE--AEALENKIEDDEE 968
                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*..
gi 1622865008 1553 ELRKKLADsdqaskvQQQKLKAVQAQGGESQQEAQRLQARLNELQAQ 1599
Cdd:TIGR02168  969 EARRRLKR-------LENKIKELGPVNLAAIEEYEELKERYDFLTAQ 1008
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
276-860 8.50e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 93.85  E-value: 8.50e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  276 RELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRAT--- 352
Cdd:COG1196    232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEerr 311
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  353 QEWLEKQAQLEKELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENppqekgevlgdvlqletLKQEAATLAANNTQL 432
Cdd:COG1196    312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE-----------------LAEAEEALLEAEAEL 374
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  433 QARVETLETEQgQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNA 512
Cdd:COG1196    375 AEAEEELEELA-EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  513 TIQQQDQELADLKQQAKEEQaqlaqtlqqqeqasqglrhQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEER 592
Cdd:COG1196    454 LEEEEEALLELLAELLEEAA-------------------LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  593 EASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQ 672
Cdd:COG1196    515 LLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALAR 594
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  673 VAELEF--QLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEqqrcISELKAETRSLVEQH 750
Cdd:COG1196    595 GAIGAAvdLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG----GSAGGSLTGGSRREL 670
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  751 KQEQKELEEEKAGRKGLEARLQQLGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAM 830
Cdd:COG1196    671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750
                          570       580       590
                   ....*....|....*....|....*....|
gi 1622865008  831 FQEQLMTLKEECEKARQELQEAKEKVAGIE 860
Cdd:COG1196    751 EALEELPEPPDLEELERELERLEREIEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
517-1313 1.07e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 94.05  E-value: 1.07e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  517 QDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASL 596
Cdd:PTZ00121  1077 KDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEI 1156
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  597 -RERDAALQQLEALEKEKAAKLEILQQQLQV--ANETRDSAQTSVTQAQReKAELSQKVEELRaRVETACREQHEAQAQv 673
Cdd:PTZ00121  1157 aRKAEDARKAEEARKAEDAKKAEAARKAEEVrkAEELRKAEDARKAEAAR-KAEEERKAEEAR-KAEDAKKAEAVKKAE- 1233
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  674 aelEFQLQSEQQKATEKERVAQEKDQLQEQLQAlkeslkvtkgslEEEKRRAADALEEQQRCISELKAETRSLVEQHKQE 753
Cdd:PTZ00121  1234 ---EAKKDAEEAKKAEEERNNEEIRKFEEARMA------------HFARRQAAIKAEEARKADELKKAEEKKKADEAKKA 1298
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  754 QKELEEEKAGRKGLEAR----LQQLGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYE--ESQQEEAQY 827
Cdd:PTZ00121  1299 EEKKKADEAKKKAEEAKkadeAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaEKKKEEAKK 1378
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  828 GAmfqEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELVELHANLARALQQVQEKEVRAQKladdlstlQE 907
Cdd:PTZ00121  1379 KA---DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKK--------AD 1447
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  908 KMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDREPEWLEEQQGRQFCSTQAALQAME----REAEQMGNELER 983
Cdd:PTZ00121  1448 EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKadeaKKAEEAKKADEA 1527
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  984 LRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELE--MRLQNALNEQRVEFATLQEALAHALTEKEG 1061
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDknMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1062 KDQELVKLR--GLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQ 1139
Cdd:PTZ00121  1608 KAEEAKKAEeaKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1140 QEQADSLERslEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQE 1219
Cdd:PTZ00121  1688 KKAAEALKK--EAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKE 1765
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1220 AERKNSLISSLEEEVSilnrqvleKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLRE 1299
Cdd:PTZ00121  1766 EEKKAEEIRKEKEAVI--------EEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVAD 1837
                          810
                   ....*....|....
gi 1622865008 1300 EAEKQRVASENLRQ 1313
Cdd:PTZ00121  1838 SKNMQLEEADAFEK 1851
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
215-916 1.18e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.58  E-value: 1.18e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL--ALLNEKQAASPLEPR------ELEELRDKNE 286
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkELYALANEISRLEQQkqilreRLANLERQLE 319
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  287 SLTMRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEH---SRATQEWLEKQAQLE 363
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetlRSKVAQLELQIASLN 399
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  364 KELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQEKGEVLGDVL-------------------QLETLKQEAAT 424
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELeelqeelerleealeelreELEEAEQALDA 479
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  425 LAANNTQLQARVETLETEQGQQE------AKLLAERDHFEEEKQQLSSLI---------------ANLQSSI-SNLSQAK 482
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLEgfsegvKALLKNQSGLSGILGVLSELIsvdegyeaaieaalgGRLQAVVvENLNAAK 559
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  483 EELEQASQAHGARLT-----------------------AQVASLTSELTTLNATIQ--------------QQDQELADLK 525
Cdd:TIGR02168  560 KAIAFLKQNELGRVTflpldsikgteiqgndreilkniEGFLGVAKDLVKFDPKLRkalsyllggvlvvdDLDNALELAK 639
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  526 QQAKEE-------------------QAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEvTRRDHAQQLA 586
Cdd:TIGR02168  640 KLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELE-ELEEELEQLR 718
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  587 TAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVEtacreq 666
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE------ 792
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  667 hEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSL 746
Cdd:TIGR02168  793 -QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL 871
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  747 VEQHKQEQKELEEEKAGRKGLEARLQQlgeahqaeteaLRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQ 826
Cdd:TIGR02168  872 ESELEALLNERASLEEALALLRSELEE-----------LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  827 ygamFQEQLMtlkeecEKARQELQEAKEKVAGIESHSEL---QISRQQNELVELHA-NLArALQQVQEKEVR-----AQK 897
Cdd:TIGR02168  941 ----LQERLS------EEYSLTLEEAEALENKIEDDEEEarrRLKRLENKIKELGPvNLA-AIEEYEELKERydfltAQK 1009
                          810       820
                   ....*....|....*....|.
gi 1622865008  898 --LADDLSTLQEKMAATSKEV 916
Cdd:TIGR02168 1010 edLTEAKETLEEAIEEIDREA 1030
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1144-1699 1.43e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 93.08  E-value: 1.43e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1144 DSLERslEAERASRAErdsaleTLQGQLEEKARELghSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERK 1223
Cdd:COG1196    203 EPLER--QAEKAERYR------ELKEELKELEAEL--LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1224 NSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEK 1303
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1304 QRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHRE 1383
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1384 ELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRG---------- 1453
Cdd:COG1196    433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADyegflegvka 512
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1454 ---------------------------LGERANLGRQFLEVELDQAREKYVQELAAVRADAETRL---AEVQREAQSTAR 1503
Cdd:COG1196    513 alllaglrglagavavligveaayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLpldKIRARAALAAAL 592
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1504 ELEVMTAKYEGA---KVKVLEERQRFQEEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSDQASkvqqqklkavQAQGG 1580
Cdd:COG1196    593 ARGAIGAAVDLVasdLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGS----------AGGSL 662
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1581 ESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQ 1660
Cdd:COG1196    663 TGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL 742
                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1622865008 1661 QAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1699
Cdd:COG1196    743 EEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
434-1239 2.94e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 92.05  E-value: 2.94e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  434 ARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNAT 513
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKR 266
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  514 IQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGlrhQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATaAEERE 593
Cdd:TIGR02169  267 LEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEA---EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAE-IEELE 342
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  594 ASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQV 673
Cdd:TIGR02169  343 REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL 422
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  674 AELEFQLQSEQQKATEKERVAQEKD-------QLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSL 746
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKAleikkqeWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARAS 502
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  747 VEQHKQEQKELEEEKAGRKGLEARLQQLG---EAHQAETE-ALRQELAEAIAAQRTAESECEQLVKEVAAWRERY----- 817
Cdd:TIGR02169  503 EERVRGGRAVEEVLKASIQGVHGTVAQLGsvgERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFlplnk 582
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  818 EESQQEEAQYGAM-----FQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQ----QNELVE--------LHAN 880
Cdd:TIGR02169  583 MRDERRDLSILSEdgvigFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRmvtlEGELFEksgamtggSRAP 662
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  881 LARALQQVQEKEvRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDREPEwlEEQQGRQF 960
Cdd:TIGR02169  663 RGGILFSRSEPA-ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQE--EEKLKERL 739
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  961 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGR-AQADLALEKAAKAELEMRLQNAln 1039
Cdd:TIGR02169  740 EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPeIQAELSKLEEEVSRIEARLREI-- 817
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1040 EQRVEFATLQEALAHalTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTG 1119
Cdd:TIGR02169  818 EQKLNRLTLEKEYLE--KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELE 895
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1120 PKLEALRAEVSKLEQQCQQQQEQADSLERSLEAerasRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKV 1199
Cdd:TIGR02169  896 AQLRELERKIEELEAQIEKKRKRLSELKAKLEA----LEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALE 971
                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1622865008 1200 QDHSKAEDEWKAQVARGRQEAERKNSLissLEEEVSILNR 1239
Cdd:TIGR02169  972 PVNMLAIQEYEEVLKRLDELKEKRAKL---EEERKAILER 1008
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1033-1731 4.33e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 4.33e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1033 RLQNALNEQRVEFATLQEALAHALTEKEGKDQelvkLRGLEAA-QIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEA 1111
Cdd:TIGR02168  190 RLEDILNELERQLKSLERQAEKAERYKELKAE----LRELELAlLVLRLEELREELEELQEELKEAEEELEELTAELQEL 265
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1112 AGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRE 1191
Cdd:TIGR02168  266 EEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK 345
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1192 LAALRTKVQDHSKAEDEWKAQvargRQEAERKNsliSSLEEEVSILNRQVLEKEGESKEL-KRLVMAESEKSQkLEDRLR 1270
Cdd:TIGR02168  346 LEELKEELESLEAELEELEAE----LEELESRL---EELEEQLETLRSKVAQLELQIASLnNEIERLEARLER-LEDRRE 417
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1271 LLQAETASNSARAAE-RSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQ---ALSTL 1346
Cdd:TIGR02168  418 RLQQEIEELLKKLEEaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQArldSLERL 497
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1347 QLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRhREELEQSKQAAGGLRAELL--------------RAQRELG----- 1407
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSGLSGILGVLSELISV-DEGYEAAIEAALGGRLQAVvvenlnaakkaiafLKQNELGrvtfl 576
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1408 --------ELIPLRQKVAEQERTAQQLRAEKASYAEQLSM--------------LKKAHGLLAEENRGL----------- 1454
Cdd:TIGR02168  577 pldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvddLDNALELAKKLRPGYrivtldgdlvr 656
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1455 --------GERANLGRQFLEVELDQAREKyVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEER--- 1523
Cdd:TIGR02168  657 pggvitggSAKTNSSILERRREIEELEEK-IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkdl 735
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1524 QRFQEEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQK 1603
Cdd:TIGR02168  736 ARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1604 EQAAEHYKLQMEKAKTHYDAKKqqnqelqeqlQSLEHLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSL 1683
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATE----------RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1622865008 1684 EAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEE 1731
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
PTZ00121 PTZ00121
MAEBL; Provisional
1012-1670 6.97e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 87.89  E-value: 6.97e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1012 ERGRAQADLALEKAAKAELEMRlqNALNEQRVEFATLQEALAHALTEKEGKDQELVKLrGLEAAQIKELEELRQTMKQLK 1091
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKK--KAEDARKAEEARKAEDARKAEEARKAEDAKRVEI-ARKAEDARKAEEARKAEDAKK 1177
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1092 EQLAKKEKE-HASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQ 1170
Cdd:PTZ00121  1178 AEAARKAEEvRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKF 1257
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1171 LEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEevsiLNRQVLEKEGESKE 1250
Cdd:PTZ00121  1258 EEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADE----AKKKAEEAKKKADA 1333
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1251 LKRLVMAESEKSQ--KLEDRLRLLQAETASNSARAAE-RSSALREEVQSLREEAEKQRVASENLR--QELTSQAERAEEL 1325
Cdd:PTZ00121  1334 AKKKAEEAKKAAEaaKAEAEAAADEAEAAEEKAEAAEkKKEEAKKKADAAKKKAEEKKKADEAKKkaEEDKKKADELKKA 1413
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1326 GQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQ-R 1404
Cdd:PTZ00121  1414 AAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKaE 1493
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1405 ELGELIPLRQKVAEQERTAQQLR-AEKASYAEQLSMLKKAHGllAEENRGLGERANLGRQFLEVELDQAREKYVQE---L 1480
Cdd:PTZ00121  1494 EAKKKADEAKKAAEAKKKADEAKkAEEAKKADEAKKAEEAKK--ADEAKKAEEKKKADELKKAEELKKAEEKKKAEeakK 1571
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1481 AAVRADAETRLAEVQREAQStARELEVMTAKYEGAKVKVlEERQRFQEEKQK---------LTAQVEQLEVFQREQTKQV 1551
Cdd:PTZ00121  1572 AEEDKNMALRKAEEAKKAEE-ARIEEVMKLYEEEKKMKA-EEAKKAEEAKIKaeelkkaeeEKKKVEQLKKKEAEEKKKA 1649
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1552 EELRKkladSDQASKVQQQKLKavqaqggesqQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQEL 1631
Cdd:PTZ00121  1650 EELKK----AEEENKIKAAEEA----------KKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK 1715
                          650       660       670
                   ....*....|....*....|....*....|....*....
gi 1622865008 1632 QEQlqslEHLQKENKELRAEAERLGHELQQAGLKTKEAE 1670
Cdd:PTZ00121  1716 KKA----EELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
223-900 8.68e-15

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 80.65  E-value: 8.68e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  223 LADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDrlALLNEKQAASPLEPRELEELRDKNESLTMRLHETLKQCQdl 302
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQ--ETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDR-- 321
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  303 ktekSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEWLEKQAQLEKELSTALQDkkcleeknei 382
Cdd:pfam12128  322 ----SELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQ---------- 387
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  383 LQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNtqlqARVETLETEQGQQEAKLLAERDHFEEEkq 462
Cdd:pfam12128  388 NNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLE----FNEEEYRLKSRLGELKLRLNQATATPE-- 461
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  463 qlssLIANLQSSISNLSQAKEELEQAsqahgarlTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQ 542
Cdd:pfam12128  462 ----LLLQLENFDERIERAREEQEAA--------NAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQL 529
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  543 EQASQGLRHqveQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEAleKEKAAKLEILQQ 622
Cdd:pfam12128  530 FPQAGTLLH---FLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDV--PEWAASEEELRE 604
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  623 QLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKerVAQEKDQLQE 702
Cdd:pfam12128  605 RLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKA--LAERKDSANE 682
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  703 QLQALKESLKVTKGSLEeekrraaDALEEQQRCISELKaetrslVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQAET 782
Cdd:pfam12128  683 RLNSLEAQLKQLDKKHQ-------AWLEEQKEQKREAR------TEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAEL 749
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  783 EALRQELAEAIAAQRTAE---SECEQLVKEVAAWRERYEESQQEEAQYGAMFQEQLMT----LKEECEKARQELQEAKEK 855
Cdd:pfam12128  750 KALETWYKRDLASLGVDPdviAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQrrprLATQLSNIERAISELQQQ 829
                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1622865008  856 VAGIESHSELQISRQQNELVELHANLARALQQVQEKEVRAQKLAD 900
Cdd:pfam12128  830 LARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
PTZ00121 PTZ00121
MAEBL; Provisional
1078-1715 1.07e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 80.57  E-value: 1.07e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1078 KELEELRQTMKQLKEQLAKKEKEHASGSGA-QSEAAGRTEPTGPKLEALRAEVSKlEQQCQQQQEQADSLERSLEAERAS 1156
Cdd:PTZ00121  1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAK-RVEIARKAEDARKAEEARKAEDAK 1176
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1157 RAERDSALETLQgqleeKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSI 1236
Cdd:PTZ00121  1177 KAEAARKAEEVR-----KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNN 1251
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1237 LNRQVLEKEGESKELKRLVMAESEKSQKLEDrLRLLQAETASNSARAAERssalREEVQSLREEAEKQRVASENLR--QE 1314
Cdd:PTZ00121  1252 EEIRKFEEARMAHFARRQAAIKAEEARKADE-LKKAEEKKKADEAKKAEE----KKKADEAKKKAEEAKKADEAKKkaEE 1326
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1315 LTSQAERAEELGQELKAWQEKFFQKEQALSTlQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGG 1394
Cdd:PTZ00121  1327 AKKKADAAKKKAEEAKKAAEAAKAEAEAAAD-EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1395 LRAELLRAQRELGELIPLRQKvAEQERTAQQLR--AEKASYAEQLSmlKKAHGLLAEENrgLGERANLGRQFLEVELDQA 1472
Cdd:PTZ00121  1406 KADELKKAAAAKKKADEAKKK-AEEKKKADEAKkkAEEAKKADEAK--KKAEEAKKAEE--AKKKAEEAKKADEAKKKAE 1480
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1473 REKYVQELAAVRADAETRLAEVQR--EAQSTARELEVMTAKYEGAKVKVLEERQRFQE----EKQKLTAQVEQLEVFQR- 1545
Cdd:PTZ00121  1481 EAKKADEAKKKAEEAKKKADEAKKaaEAKKKADEAKKAEEAKKADEAKKAEEAKKADEakkaEEKKKADELKKAEELKKa 1560
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1546 ------EQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKT 1619
Cdd:PTZ00121  1561 eekkkaEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKK 1640
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1620 HYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1699
Cdd:PTZ00121  1641 KEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEE 1720
                          650
                   ....*....|....*.
gi 1622865008 1700 FQVATDALKSREPQAK 1715
Cdd:PTZ00121  1721 LKKAEEENKIKAEEAK 1736
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
887-1663 1.30e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.10  E-value: 1.30e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  887 QVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDREPEwLEEQQGRQFcSTQAA 966
Cdd:TIGR02168  219 KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE-IEELQKELY-ALANE 296
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  967 LQAMEREAEQMGNELERLR---AALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNA---LNE 1040
Cdd:TIGR02168  297 ISRLEQQKQILRERLANLErqlEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELesrLEE 376
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1041 QRVEFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAgrTEPTGP 1120
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE--LEELQE 454
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1121 KLEALRAEVSKLEQQCQQQQEQADSLERSLEAERAsraeRDSALETLQGQLEEKARELghsqSALASVQRELAALRTKVQ 1200
Cdd:TIGR02168  455 ELERLEEALEELREELEEAEQALDAAERELAQLQA----RLDSLERLQENLEGFSEGV----KALLKNQSGLSGILGVLS 526
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1201 DHSKAEDEWKA------------------QVARGRQEAERKNSLI-SSLEEEVSILNRQVLEKEGESKELKRLVMAESEK 1261
Cdd:TIGR02168  527 ELISVDEGYEAaieaalggrlqavvvenlNAAKKAIAFLKQNELGrVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD 606
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1262 SQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREE----AEKQRV--------ASENLRQELTSQAERAEELGQEL 1329
Cdd:TIGR02168  607 LVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYrivtLDGDLVrpggvitgGSAKTNSSILERRREIEELEEKI 686
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1330 KAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRE---- 1405
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEieel 766
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1406 LGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEEnrglgeranlgrqfleveldqarekyVQELAAVRA 1485
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE--------------------------LTLLNEEAA 820
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1486 DAETRLAEVQREAQSTARELEVMTakyegakvkvlEERQRFQEEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSDQAS 1565
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLE-----------EQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1566 KVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQkeqaaehYKLQMEKAKthydakkQQNQELQEQLQSL------E 1639
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRELEELREKLAQ-------LELRLEGLE-------VRIDNLQERLSEEysltleE 955
                          810       820       830
                   ....*....|....*....|....*....|
gi 1622865008 1640 HLQKENK------ELRAEAERLGHELQQAG 1663
Cdd:TIGR02168  956 AEALENKieddeeEARRRLKRLENKIKELG 985
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
566-1269 2.54e-14

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 79.11  E-value: 2.54e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  566 QLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAA-KLEILQQQLQVANETRDSAQTSVTQAQR- 643
Cdd:pfam12128  213 PPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHlHFGYKSDETLIASRQEERQETSAELNQLl 292
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  644 --EKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEK-DQLQEQLQALKESLKVTKGSL-- 718
Cdd:pfam12128  293 rtLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQlPSWQSELENLEERLKALTGKHqd 372
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  719 --EEEKRRAADALEEQQRCISELKAETRslveqhkqeqkeleeekagrKGLEARLQQLGEAhQAETEALRQELAEAIAAQ 796
Cdd:pfam12128  373 vtAKYNRRRSKIKEQNNRDIAGIKDKLA--------------------KIREARDRQLAVA-EDDLQALESELREQLEAG 431
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  797 RTAESECEQLVKEVAAWreryEESQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVagieshselqiSRQQNELVE 876
Cdd:pfam12128  432 KLEFNEEEYRLKSRLGE----LKLRLNQATATPELLLQLENFDERIERAREEQEAANAEV-----------ERLQSELRQ 496
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  877 LHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVarLETLVRKAGEQQETASRELVKEPARAGDREPEWLEEQ- 955
Cdd:pfam12128  497 ARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTL--LHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSv 574
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  956 -QGRQFCSTQAALQAMER-EAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMR 1033
Cdd:pfam12128  575 gGELNLYGVKLDLKRIDVpEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLD 654
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1034 LQNALNEQRVEFATLQEALAhalTEKEGKDQELVKLrgleAAQIKELE-ELRQTMKQLKEQLakkekehasgsgaqseaa 1112
Cdd:pfam12128  655 LRRLFDEKQSEKDKKNKALA---ERKDSANERLNSL----EAQLKQLDkKHQAWLEEQKEQK------------------ 709
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1113 grTEPTGPKLEALRAEVSKLEQQCqqqqeqaDSLERSLEAERASRAERDSALETlqgQLEEKARELGHSQSALASVQREL 1192
Cdd:pfam12128  710 --REARTEKQAYWQVVEGALDAQL-------ALLKAAIAARRSGAKAELKALET---WYKRDLASLGVDPDVIAKLKREI 777
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1193 AALRTKV----QDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDR 1268
Cdd:pfam12128  778 RTLERKIeriaVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVR 857

                   .
gi 1622865008 1269 L 1269
Cdd:pfam12128  858 L 858
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
215-926 2.95e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.96  E-value: 2.95e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAmmqQRIDRLALLNEKqaASPLEPRELEELRDKNESLTMRLHE 294
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLE---EIEQLLEELNKK--IKDLGEEEQLRVKEKIGELEAEIAS 305
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  295 TLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEWLEKQAQLE---KELSTALQ 371
Cdd:TIGR02169  306 LERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEevdKEFAETRD 385
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  372 DKKCLEEKNEILQGKLSQLEEHLALLRENPPQEKGEvlgdvlqLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLL 451
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEE-------LADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  452 AERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQ----------------VASLTSELTT------ 509
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVrggraveevlkasiqgVHGTVAQLGSvgerya 538
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  510 ----------LNATIQQQDQELADLKQQAKEEQAQLA------QTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKE---- 569
Cdd:TIGR02169  539 taievaagnrLNNVVVEDDAVAKEAIELLKRRKAGRAtflplnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafky 618
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  570 ------VAEKQEVTRR--DHAQQLATAAEEREAS-------LRERDAALQQLEALEK--EKAAKLEILQQQLQVANETRD 632
Cdd:TIGR02169  619 vfgdtlVVEDIEAARRlmGKYRMVTLEGELFEKSgamtggsRAPRGGILFSRSEPAElqRLRERLEGLKRELSSLQSELR 698
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  633 SAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKAT----EKERVAQEKDQLQEQLQALK 708
Cdd:TIGR02169  699 RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEnvksELKELEARIEELEEDLHKLE 778
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  709 ESLKVTKGSLEEEK----RRAADALEEQQRCI----SELKAETRSLVEQHKQEQKELEEEKAGRKGLEAR---LQQLGEA 777
Cdd:TIGR02169  779 EALNDLEARLSHSRipeiQAELSKLEEEVSRIearlREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQiksIEKEIEN 858
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  778 HQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAMFQ---EQLMTLKEECEKARQELQEAKE 854
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEkkrKRLSELKAKLEALEEELSEIED 938
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  855 KVAGIESHSE---------LQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRK 925
Cdd:TIGR02169  939 PKGEDEEIPEeelsledvqAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018

                   .
gi 1622865008  926 A 926
Cdd:TIGR02169 1019 V 1019
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
236-990 3.46e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.96  E-value: 3.46e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  236 ELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQaasplepRELEELRDKNESLtmRLHETLKQCQDLKTEKSQMDRKISQ 315
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRREREKA-------ERYQALLKEKREY--EGYELLKEKEALERQKEAIERQLAS 248
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  316 LLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEwleKQAQLEKELSTALQDKKCLEEKNEILQGKLSQLEEHLA 395
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE---EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  396 LLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSI 475
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELK 405
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  476 SNLSQAKEELEQASQAHG------ARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGL 549
Cdd:TIGR02169  406 RELDRLQEELQRLSEELAdlnaaiAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKEL 485
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  550 RHQVEQLSSSLKQKEQQLKEVAEKQEVT--------------------RRDHAQQLATAAEEREAS-------------- 595
Cdd:TIGR02169  486 SKLQRELAEAEAQARASEERVRGGRAVEevlkasiqgvhgtvaqlgsvGERYATAIEVAAGNRLNNvvveddavakeaie 565
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  596 -LRERDAA------LQQLEALEKEKAAKLE----------------------------ILQQQLQVANETRDSAQ----- 635
Cdd:TIGR02169  566 lLKRRKAGratflpLNKMRDERRDLSILSEdgvigfavdlvefdpkyepafkyvfgdtLVVEDIEAARRLMGKYRmvtle 645
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  636 --------------TSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELE---FQLQSEQQKATEK-ERVAQEK 697
Cdd:TIGR02169  646 gelfeksgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEnrlDELSQELSDASRKiGEIEKEI 725
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  698 DQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVE-QHKQEQKELEEEKAGRKGLEARLQQLGE 776
Cdd:TIGR02169  726 EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKlEEALNDLEARLSHSRIPEIQAELSKLEE 805
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  777 AHQ---AETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQygamFQEQLMTLKEECEKARQELQEAK 853
Cdd:TIGR02169  806 EVSrieARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN----LNGKKEELEEELEELEAALRDLE 881
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  854 EKVAGIEShselQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETlvrkagEQQETA 933
Cdd:TIGR02169  882 SRLGDLKK----ERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE------IPEEEL 951
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622865008  934 SRELVKEPARAGDREPEWLEEQQGRqfcstqaALQAMEREAEQMgNELERLRAALME 990
Cdd:TIGR02169  952 SLEDVQAELQRVEEEIRALEPVNML-------AIQEYEEVLKRL-DELKEKRAKLEE 1000
PTZ00121 PTZ00121
MAEBL; Provisional
1187-1731 4.45e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 78.64  E-value: 4.45e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1187 SVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMA-ESEKSQKL 1265
Cdd:PTZ00121  1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIArKAEDARKA 1166
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1266 EDRLRLLQAETASNSARAAERSSAlrEEVQSLRE--EAEKQRVASENLRQELTSQAERAEELGQELKAwqEKFFQKEQAL 1343
Cdd:PTZ00121  1167 EEARKAEDAKKAEAARKAEEVRKA--EELRKAEDarKAEAARKAEEERKAEEARKAEDAKKAEAVKKA--EEAKKDAEEA 1242
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1344 STLQLEHTSTQALVSELLPAKHLcQQLQAEQAAAEKRHREELEQSKQAAgglRAELLRAQRELGELIPLRQKvAEQERTA 1423
Cdd:PTZ00121  1243 KKAEEERNNEEIRKFEEARMAHF-ARRQAAIKAEEARKADELKKAEEKK---KADEAKKAEEKKKADEAKKK-AEEAKKA 1317
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1424 QQLRAEKASYAEQLSMLKKAhgllAEENRGLGERANLGRQFLEVELDQAREK-----YVQELAAVRADAETRLAEVQREA 1498
Cdd:PTZ00121  1318 DEAKKKAEEAKKKADAAKKK----AEEAKKAAEAAKAEAEAAADEAEAAEEKaeaaeKKKEEAKKKADAAKKKAEEKKKA 1393
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1499 QSTARELEVMTAKYEgaKVKVLEERQRFQEEKQKLTAQVEQLEVFQR--EQTKQVEELRKKladSDQASKVQQQKLKAVQ 1576
Cdd:PTZ00121  1394 DEAKKKAEEDKKKAD--ELKKAAAAKKKADEAKKKAEEKKKADEAKKkaEEAKKADEAKKK---AEEAKKAEEAKKKAEE 1468
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1577 AQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLG 1656
Cdd:PTZ00121  1469 AKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKA 1548
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1657 HELQQA-----GLKTKEAEQTCRHLTAQVRSL-EAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCE 1730
Cdd:PTZ00121  1549 DELKKAeelkkAEEKKKAEEAKKAEEDKNMALrKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA 1628

                   .
gi 1622865008 1731 E 1731
Cdd:PTZ00121  1629 E 1629
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
786-1656 4.46e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.57  E-value: 4.46e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  786 RQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGamfqEQLMTLKEECEKAR--QELQEAKEKVAGIESHS 863
Cdd:TIGR02169  155 RRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLIIDEKR----QQLERLRREREKAEryQALLKEKREYEGYELLK 230
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  864 EL-----QISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEK-MAATSKEVARLETLVRKAGEQQETASREL 937
Cdd:TIGR02169  231 EKealerQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVKEKIGELEAEIASLERSI 310
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  938 vkepaRAGDREPEWLEEQQGRqfcsTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQ 1017
Cdd:TIGR02169  311 -----AEKERELEDAEERLAK----LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA 381
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1018 ADLALEKAAKAELEMrLQNALNEQRVEFATLQEalahaltEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKK 1097
Cdd:TIGR02169  382 ETRDELKDYREKLEK-LKREINELKRELDRLQE-------ELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ 453
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1098 EKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARE 1177
Cdd:TIGR02169  454 EWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSV 533
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1178 LGHSQSAL-ASVQRELAALRTKVQDHSKAEDEWKAQVARGR------QEAERKNSLISSLEEEVSI---LNRQVLEKEGE 1247
Cdd:TIGR02169  534 GERYATAIeVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRatflplNKMRDERRDLSILSEDGVIgfaVDLVEFDPKYE 613
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1248 SKEL----KRLVMAESEKSQKLEDRLRLLQAET-----------ASNSARAAE-RSSALREEVQSLREEAEKQRVASENL 1311
Cdd:TIGR02169  614 PAFKyvfgDTLVVEDIEAARRLMGKYRMVTLEGelfeksgamtgGSRAPRGGIlFSRSEPAELQRLRERLEGLKRELSSL 693
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1312 RQELTSQAERAEELGQELKAWQEKffqkeqaLSTLQLEhtstqalvsellpakhlcqqlqaeqaaaekrhREELEQSKQA 1391
Cdd:TIGR02169  694 QSELRRIENRLDELSQELSDASRK-------IGEIEKE--------------------------------IEQLEQEEEK 734
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1392 AGGLRAELLRAQRElgelipLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAhgllaeenrglgeRANLGRQFLEVELDQ 1471
Cdd:TIGR02169  735 LKERLEELEEDLSS------LEQEIENVKSELKELEARIEELEEDLHKLEEA-------------LNDLEARLSHSRIPE 795
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1472 AREKYvQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEerqrFQEEKQKLTAQVEQLEVFQREQTKQV 1551
Cdd:TIGR02169  796 IQAEL-SKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRID----LKEQIKSIEKEIENLNGKKEELEEEL 870
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1552 EELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMekakTHYDAKKQQNQEL 1631
Cdd:TIGR02169  871 EELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL----SEIEDPKGEDEEI 946
                          890       900
                   ....*....|....*....|....*
gi 1622865008 1632 QEQLQSLEHLQKENKELRAEAERLG 1656
Cdd:TIGR02169  947 PEEELSLEDVQAELQRVEEEIRALE 971
PTZ00121 PTZ00121
MAEBL; Provisional
215-856 1.06e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.49  E-value: 1.06e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEP-------RELEELRDKNES 287
Cdd:PTZ00121  1144 EARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAarkaeeeRKAEEARKAEDA 1223
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  288 LTM----RLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDAlneltEEHSRATQEWLEKQAQLE 363
Cdd:PTZ00121  1224 KKAeavkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-----DELKKAEEKKKADEAKKA 1298
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  364 KELSTALQDKKCLEEKNEILQGKLSQLEehlALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQ 443
Cdd:PTZ00121  1299 EEKKKADEAKKKAEEAKKADEAKKKAEE---AKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE 1375
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  444 GQQEAKLLAERdhfEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTlNATIQQQDQELAD 523
Cdd:PTZ00121  1376 AKKKADAAKKK---AEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK-KAEEAKKADEAKK 1451
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  524 LKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAE--KQEVTRRDHAQQLATAAEEREA-SLRERD 600
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADeaKKAAEAKKKADEAKKAEEAKKAdEAKKAE 1531
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  601 AALQQLEALEKEKAAKLEILQ--QQLQVANETRDSAQTSVTQAQRE----KAELSQKVEELRArvetacreqhEAQAQVA 674
Cdd:PTZ00121  1532 EAKKADEAKKAEEKKKADELKkaEELKKAEEKKKAEEAKKAEEDKNmalrKAEEAKKAEEARI----------EEVMKLY 1601
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  675 ELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKgslEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQ 754
Cdd:PTZ00121  1602 EEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE---AEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE 1678
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  755 KELEEEKAGRKGLEARLQQLGEAHQAEtEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQ-EEAQYGAMFQE 833
Cdd:PTZ00121  1679 EAKKAEEDEKKAAEALKKEAEEAKKAE-ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKaEEAKKDEEEKK 1757
                          650       660
                   ....*....|....*....|...
gi 1622865008  834 QLMTLKEECEKARQELQEAKEKV 856
Cdd:PTZ00121  1758 KIAHLKKEEEKKAEEIRKEKEAV 1780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
415-746 1.35e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.02  E-value: 1.35e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  415 LETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHgA 494
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL-T 757
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  495 RLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEeqaqLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLkEVAEKQ 574
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ----LKEELKALREALDELRAELTLLNEEAANLRERL-ESLERR 832
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  575 EVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEE 654
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE 912
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  655 LRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQE------------KDQLQEQLQALK-------------- 708
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEeaealenkieddEEEARRRLKRLEnkikelgpvnlaai 992
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 1622865008  709 ---ESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSL 746
Cdd:TIGR02168  993 eeyEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
HkD_SF cd22211
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ...
8-136 1.77e-13

Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.


Pssm-ID: 411792  Cd Length: 145  Bit Score: 69.61  E-value: 1.77e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008    8 GAALLSWVNSLHVADPVEAVLQLQDCSIFIKI---IDRLHGTEEGQQILQQPVP-----ERLDFVCSFLQK----NQKHP 75
Cdd:cd22211      1 EAALLAWINTFPLSSPVESLDDLSDGVVLAEIlsqIDPSYFDSEWLESRDSSDNwvlklNNLKKLYRSLSKyyreVLGQQ 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622865008   76 SSPECLVSAQKVLE-GSELELAKMTMLLLYHSTMSSKSPRD---WEQFEYKIQAELAVILKFVLD 136
Cdd:cd22211     81 LSDLPLPDLSAIARdGDEEEIVKLLELVLGAAVQCENKEEYiarIQQLDESTQAELMLIIQEVLE 145
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
430-932 5.33e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 74.69  E-value: 5.33e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  430 TQLQARVETLETEqgqqEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHgARLTAQVASLTSELTT 509
Cdd:PRK02224   202 KDLHERLNGLESE----LAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEI-EDLRETIAETEREREE 276
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  510 LNATIQQQDQ---ELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEvAEKQEVTRRDHAQQLA 586
Cdd:PRK02224   277 LAEEVRDLRErleELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQA-HNEEAESLREDADDLE 355
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  587 TAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANE-------TRDSAQTSVTQAQREKAELSQKVEELRARV 659
Cdd:PRK02224   356 ERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdapvDLGNAEDFLEELREERDELREREAELEATL 435
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  660 ETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCisEL 739
Cdd:PRK02224   436 RTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRI--ER 513
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  740 KAETRSLVEQHKQEQkeleeekagRKGLEARLQQLGEAHqAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEE 819
Cdd:PRK02224   514 LEERREDLEELIAER---------RETIEEKRERAEELR-ERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAE 583
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  820 SQQEEAQYGAMfqEQLMTLKEECEKARQELQEAKEKVAGI------------ESHSELQISRQQNELVELHANLARA--- 884
Cdd:PRK02224   584 LKERIESLERI--RTLLAAIADAEDEIERLREKREALAELnderrerlaekrERKRELEAEFDEARIEEAREDKERAeey 661
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622865008  885 LQQVQEK--EVRAQKLA------------DDLSTLQEKMAATSKEVARLETLVRKAGEQQET 932
Cdd:PRK02224   662 LEQVEEKldELREERDDlqaeigavenelEELEELRERREALENRVEALEALYDEAEELESM 723
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
553-1543 1.05e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.95  E-value: 1.05e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  553 VEQLSSSLKQKEQQLKEVAEKQEVTR---RDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANE 629
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDliiDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIER 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  630 TRDSAQTSVTQAQREKAELSQKVEELRARVEtacreqheaqaqvaelefQLQSEQQKATEKERVaqekdQLQEQLQALKE 709
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLE------------------ELNKKIKDLGEEEQL-----RVKEKIGELEA 301
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  710 SLKVTKGSLEEEKRRAADALEEQQrcisELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLgeahQAETEALRQEL 789
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEERLA----KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL----KEELEDLRAEL 373
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  790 AEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQygamfqeqlmtLKEECEKARQELQEAKEKVAGIEShselqisr 869
Cdd:TIGR02169  374 EEVDKEFAETRDELKDYREKLEKLKREINELKRELDR-----------LQEELQRLSEELADLNAAIAGIEA-------- 434
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  870 qqnELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLEtlvrkagEQQETASRELVKEPARAGdrep 949
Cdd:TIGR02169  435 ---KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE-------KELSKLQRELAEAEAQAR---- 500
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  950 EWLEEQQGRQFCST--QAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVAR-----LTQERGRAQADLAL 1022
Cdd:TIGR02169  501 ASEERVRGGRAVEEvlKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKeaielLKRRKAGRATFLPL 580
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1023 EKAAKAELEMRLqnALNEQRVEFATlqealahALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQ-----LKEQLAKK 1097
Cdd:TIGR02169  581 NKMRDERRDLSI--LSEDGVIGFAV-------DLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKyrmvtLEGELFEK 651
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1098 EKEHASGSGAQSEAAGRTEPTGPKLEALRAEVskleqqcqqqqeqaDSLERSLEAERASRAERDSALETLQGQLEEKARE 1177
Cdd:TIGR02169  652 SGAMTGGSRAPRGGILFSRSEPAELQRLRERL--------------EGLKRELSSLQSELRRIENRLDELSQELSDASRK 717
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1178 LGHSQSALASVQRELAALRtkvqdhskaedewkaqvargrQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMA 1257
Cdd:TIGR02169  718 IGEIEKEIEQLEQEEEKLK---------------------ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHK 776
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1258 ESEKSQKLEDRLRllqaetasnsaraaerssalREEVQSLREEAEKqrvasenLRQELTSQAERAEELGQELKAWQEKFF 1337
Cdd:TIGR02169  777 LEEALNDLEARLS--------------------HSRIPEIQAELSK-------LEEEVSRIEARLREIEQKLNRLTLEKE 829
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1338 QKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGElipLRQKVA 1417
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE---LERKIE 906
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1418 EQERTAQQLRaekasyaEQLSMLKKAHGLLAEENRGLGEraNLGRQFLEVELDQAREKYVQELAAVRADAEtRLAEVQRE 1497
Cdd:TIGR02169  907 ELEAQIEKKR-------KRLSELKAKLEALEEELSEIED--PKGEDEEIPEEELSLEDVQAELQRVEEEIR-ALEPVNML 976
                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|....*...
gi 1622865008 1498 AQSTARELEVMTAKYEGAKVKVLEERqrfqEEKQKLTAQVEQL--EVF 1543
Cdd:TIGR02169  977 AIQEYEEVLKRLDELKEKRAKLEEER----KAILERIEEYEKKkrEVF 1020
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
350-1102 1.29e-12

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 73.47  E-value: 1.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  350 RATQEWLEKQAQLEKELSTALQDKKcLEEKNEILQGKLSQLEEHLALLRENPPQEKgevlgdvlqlETLKQEAATLAANN 429
Cdd:pfam02463  146 IIAMMKPERRLEIEEEAAGSRLKRK-KKEALKKLIEETENLAELIIDLEELKLQEL----------KLKEQAKKALEYYQ 214
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  430 TQLQARvetlETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTT 509
Cdd:pfam02463  215 LKEKLE----LEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKL 290
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  510 LNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRhQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAA 589
Cdd:pfam02463  291 LAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK-KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLE 369
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  590 EEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETAcREQHEA 669
Cdd:pfam02463  370 QLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELK-QGKLTE 448
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  670 QAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:pfam02463  449 EKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAH 528
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  750 HKQEQKELEEEKAGRKGLEARLQQLGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGA 829
Cdd:pfam02463  529 GRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQL 608
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  830 MFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKM 909
Cdd:pfam02463  609 DKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESE 688
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  910 AATSKEVARLETLVRKAGEQQETASRELVKEPARAGDREPEWLEEQQGRQFCSTQAALQAMEREA----EQMGNELERLR 985
Cdd:pfam02463  689 LAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEksrlKKEEKEEEKSE 768
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  986 AALMESQGQQQEERGQQEREVARLTQERGRAQADLA------LEKAAKAELEMRLQNALNEQRVEFATLQEALAHALTEK 1059
Cdd:pfam02463  769 LSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRaleeelKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKL 848
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 1622865008 1060 EGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHA 1102
Cdd:pfam02463  849 EKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESK 891
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1021-1697 2.05e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.79  E-value: 2.05e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1021 ALEKAAKAELEM-RLQNALNEQRVEFATLQEALAHA-----LTEKEGKDQELVKLRGLEAAQ------IKELEELRQTMK 1088
Cdd:TIGR02169  175 ALEELEEVEENIeRLDLIIDEKRQQLERLRREREKAeryqaLLKEKREYEGYELLKEKEALErqkeaiERQLASLEEELE 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1089 QLKEQLAKKEKEHASGSGAQSEAAGRTEPTGP--------KLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAER 1160
Cdd:TIGR02169  255 KLTEEISELEKRLEEIEQLLEELNKKIKDLGEeeqlrvkeKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1161 DSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVargrqeaerknsliSSLEEEVSILNRq 1240
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL--------------KDYREKLEKLKR- 399
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1241 vlekegESKELKRLVMAESEKSQKLEDRLRLLQAETasnsARAAERSSALREEVQSLREEAEKQRvasenlrqeltsqaE 1320
Cdd:TIGR02169  400 ------EINELKRELDRLQEELQRLSEELADLNAAI----AGIEAKINELEEEKEDKALEIKKQE--------------W 455
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1321 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKhlcqQLQAEQAAAEKRHREELEQSKQAAGGLRAELL 1400
Cdd:TIGR02169  456 KLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA----RASEERVRGGRAVEEVLKASIQGVHGTVAQLG 531
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1401 RAQRELGELIP------LRQKVAEQERTAQQ----LRAEKASYAEQLSMLKKAHGLLaeENRGLGERANLGRQFLEVELD 1470
Cdd:TIGR02169  532 SVGERYATAIEvaagnrLNNVVVEDDAVAKEaielLKRRKAGRATFLPLNKMRDERR--DLSILSEDGVIGFAVDLVEFD 609
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1471 QARE---KYVQELAAVRADAET--RLAEVQREAQSTARELE---VMTAKY------EGAKVKVLEERQRFQEEKQKLTAQ 1536
Cdd:TIGR02169  610 PKYEpafKYVFGDTLVVEDIEAarRLMGKYRMVTLEGELFEksgAMTGGSraprggILFSRSEPAELQRLRERLEGLKRE 689
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1537 VEQLEVFQREQTKQVEELRKKLADSdqaskvqQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEK 1616
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSDA-------SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE 762
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1617 AKTHYDAKKQQNQELQEQLQSLEH--LQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQL 1694
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQR 842

                   ...
gi 1622865008 1695 RDL 1697
Cdd:TIGR02169  843 IDL 845
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
586-1101 1.18e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.45  E-value: 1.18e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  586 ATAAEEREASLRERdaaLQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVT---QAQREKAELSQKVEELRARVETA 662
Cdd:PRK02224   194 AQIEEKEEKDLHER---LNGLESELAELDEEIERYEEQREQARETRDEADEVLEeheERREELETLEAEIEDLRETIAET 270
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  663 CREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKEslkvtkgSLEEEKRRAADALEEQQRCISELKAE 742
Cdd:PRK02224   271 EREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARRE-------ELEDRDEELRDRLEECRVAAQAHNEE 343
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  743 TRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEA---HQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEE 819
Cdd:PRK02224   344 AESLREDADDLEERAEELREEAAELESELEEAREAvedRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDE 423
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  820 SQQEEAQYGAmfqeQLMTLKEECEKARQELQEAK-----EKVAGIESHSELQISRQQNElvELHANLARALQQVQEKEVR 894
Cdd:PRK02224   424 LREREAELEA----TLRTARERVEEAEALLEAGKcpecgQPVEGSPHVETIEEDRERVE--ELEAELEDLEEEVEEVEER 497
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  895 ------AQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETaSRELVKEPARAGDREPEWLEEQQGRQfCSTQAALQ 968
Cdd:PRK02224   498 leraedLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE-LRERAAELEAEAEEKREAAAEAEEEA-EEAREEVA 575
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  969 AMEREAEQMGNELERLRA-----ALMESQGQQQEERGQQEREVARLTQERgraQADLALEKAAKAELEMRLQNA----LN 1039
Cdd:PRK02224   576 ELNSKLAELKERIESLERirtllAAIADAEDEIERLREKREALAELNDER---RERLAEKRERKRELEAEFDEArieeAR 652
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622865008 1040 EQRVEFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEH 1101
Cdd:PRK02224   653 EDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEALEALY 714
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
406-711 1.91e-11

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 69.86  E-value: 1.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  406 GEVLGDVLQLETLKQEAATLAANNTQLQARVETLeteqgQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKeeL 485
Cdd:NF012221  1528 GYILDNVVATSESSQQADAVSKHAKQDDAAQNAL-----ADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNA--L 1600
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  486 EQASQAHGARLTAQVASLTSELTTLNATIQQ---QDQELADLKQQAKEEQAQLAQTLQQQEQASQGL--RHQVEQLSSSL 560
Cdd:NF012221  1601 ETNGQAQRDAILEESRAVTKELTTLAQGLDAldsQATYAGESGDQWRNPFAGGLLDRVQEQLDDAKKisGKQLADAKQRH 1680
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  561 KQKEQQLKEVAEKQE--VTRRDHAQQLATAAEER---EASLRERDAALQQLEALEKEKAAKLEIlqQQLQVANETRDSAQ 635
Cdd:NF012221  1681 VDNQQKVKDAVAKSEagVAQGEQNQANAEQDIDDakaDAEKRKDDALAKQNEAQQAESDANAAA--NDAQSRGEQDASAA 1758
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  636 TSVT-QAQREKAELSQ----KVEELRARVETACREQHEAQAqVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKES 710
Cdd:NF012221  1759 ENKAnQAQADAKGAKQdesdKPNRQGAAGSGLSGKAYSVEG-VAEPGSHINPDSPAAADGRFSEGLTEQEQEALEGATNA 1837

                   .
gi 1622865008  711 L 711
Cdd:NF012221  1838 V 1838
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
402-1100 2.06e-11

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 69.61  E-value: 2.06e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  402 PQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQA 481
Cdd:TIGR00618  162 SKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQS 241
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  482 KEELEQASQAHGARLTAQVA--SLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSS 559
Cdd:TIGR00618  242 HAYLTQKREAQEEQLKKQQLlkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMR 321
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  560 LKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVanetrdsaqTSVT 639
Cdd:TIGR00618  322 SRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQK---------TTLT 392
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  640 QAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEkdQLQEQLQALKESLKVTKGSLE 719
Cdd:TIGR00618  393 QKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITC--TAQCEKLEKIHLQESAQSLKE 470
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  720 EEKrraadaLEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGR-KGLEARLQQLGE--AHQAETEALRQELAEAIAAQ 796
Cdd:TIGR00618  471 REQ------QLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGScIHPNPARQDIDNpgPLTRRMQRGEQTYAQLETSE 544
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  797 RTAESECEQLVKEVAAWRERYEESQQEEAQYGAMFQEqlmtLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELVE 876
Cdd:TIGR00618  545 EDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNR----SKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRK 620
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  877 LHANLARaLQQVQEKEVRAQKLADDLSTLQEkmaatskevarletlvrkageQQETASRELVKEPARAgdrepewLEEQQ 956
Cdd:TIGR00618  621 LQPEQDL-QDVRLHLQQCSQELALKLTALHA---------------------LQLTLTQERVREHALS-------IRVLP 671
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  957 GRQFCSTQAALQAMEREAEQMGNELERLrAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQN 1036
Cdd:TIGR00618  672 KELLASRQLALQKMQSEKEQLTYWKEML-AQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMH 750
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622865008 1037 ALNEQRVEFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKE 1100
Cdd:TIGR00618  751 QARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPS 814
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
205-836 6.15e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 6.15e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  205 MGDILQTPQFQMRRLKKQLADErsnrDELELELAENRKLLTEKDAQIAMMQQRIDRLAllnEKQAASPLEPRELEELRDK 284
Cdd:PRK03918   167 LGEVIKEIKRRIERLEKFIKRT----ENIEELIKEKEKELEEVLREINEISSELPELR---EELEKLEKEVKELEELKEE 239
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  285 NESLTMRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFAShLQQLQDALNELTEEHSratqEWLEKQAQLEK 364
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE-LKEKAEEYIKLSEFYE----EYLDELREIEK 314
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  365 ELSTALQDKKCLEEKNEILQGKLSQLEEhLALLRENPPQEKGEVLGDVLQLETLKQeaatLAANNTQLQARVETLETEQG 444
Cdd:PRK03918   315 RLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHELYEEAKA----KKEELERLKKRLTGLTPEKL 389
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  445 QQEAKLLAER-DHFEEEKQQLSSLIANLQSSISNLSQAKEELEQA-----------SQAHGARLtaqVASLTSELTTLNA 512
Cdd:PRK03918   390 EKELEELEKAkEEIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpvcgrelTEEHRKEL---LEEYTAELKRIEK 466
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  513 TIQQQDQELADLKQQAKEEQAQLAQtlqqqeqasqglrhqvEQLSSSLKQKEQQLKEVAEKQEVTrrdHAQQLATAAEER 592
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKVLKK----------------ESELIKLKELAEQLKELEEKLKKY---NLEELEKKAEEY 527
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  593 EASLRERDAALQQLEALEKEkAAKLEILQQQLQVANETRDSaqtsvtqAQREKAELSQKVEEL----RARVETACREQHE 668
Cdd:PRK03918   528 EKLKEKLIKLKGEIKSLKKE-LEKLEELKKKLAELEKKLDE-------LEEELAELLKELEELgfesVEELEERLKELEP 599
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  669 AQAQVAELefqLQSEQQKATEKERVAQEKDQLQEQLqalkESLKVTKGSLEEEKRRaadaLEEQQRCISElkaetrslvE 748
Cdd:PRK03918   600 FYNEYLEL---KDAEKELEREEKELKKLEEELDKAF----EELAETEKRLEELRKE----LEELEKKYSE---------E 659
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  749 QHKQEQKELEEEKAGRKGLEARLQQLgEAHQAETEALRQELAEAIAAQRTAESECEQLVKEvaawRERYEESQQEEAQYG 828
Cdd:PRK03918   660 EYEELREEYLELSRELAGLRAELEEL-EKRREEIKKTLEKLKEELEEREKAKKELEKLEKA----LERVEELREKVKKYK 734

                   ....*...
gi 1622865008  829 AMFQEQLM 836
Cdd:PRK03918   735 ALLKERAL 742
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
885-1695 6.36e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.17  E-value: 6.36e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  885 LQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRkagEQQETASRELVKEpARAGDREPEWLEeqqgRQFCSTQ 964
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLK---EKREYEGYELLKE-KEALERQKEAIE----RQLASLE 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  965 AALQAMEREAEQMGNELERLRAALMEsqgQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRVE 1044
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEE---LNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1045 FATLQEALAhaltEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEA 1124
Cdd:TIGR02169  328 EAEIDKLLA----EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE 403
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1125 LRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSK 1204
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEK 483
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1205 AEDEWKAQVARgrQEAERKnslISSLEEEVSILNRQVLEK--EGESKELKRLVMAESEKSQKLE----DRLRLLQAETAS 1278
Cdd:TIGR02169  484 ELSKLQRELAE--AEAQAR---ASEERVRGGRAVEEVLKAsiQGVHGTVAQLGSVGERYATAIEvaagNRLNNVVVEDDA 558
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1279 NSARAAE---RSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQL--EHTST 1353
Cdd:TIGR02169  559 VAKEAIEllkRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAarRLMGK 638
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1354 QALVS---ELLPAKHLCQQLQAEQAAAEKRHREELEQSKQaaggLRAELLRAQRELGELiplRQKVAEQERTAQQLRAEK 1430
Cdd:TIGR02169  639 YRMVTlegELFEKSGAMTGGSRAPRGGILFSRSEPAELQR----LRERLEGLKRELSSL---QSELRRIENRLDELSQEL 711
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1431 ASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRAdaetRLAEVQREAQSTARELEVMTA 1510
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS-SLEQEIENVKSELKELEA----RIEELEEDLHKLEEALNDLEA 786
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1511 KYEGAKVKVLEERQRFQEEkqkltaqveqlevfqreqtkQVEELRKKLADSDQaskvqqqKLKAVQAQGGESQQEAQRLQ 1590
Cdd:TIGR02169  787 RLSHSRIPEIQAELSKLEE--------------------EVSRIEARLREIEQ-------KLNRLTLEKEYLEKEIQELQ 839
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1591 ARLNELQAQLSQKEQAAEHYKLQMEKakthydaKKQQNQELQEQLQSLE----HLQKENKELRAEAERLGHELQQAGLKT 1666
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEE-------LEEELEELEAALRDLEsrlgDLKKERDELEAQLRELERKIEELEAQI 912
                          810       820
                   ....*....|....*....|....*....
gi 1622865008 1667 KEAEQTCRHLTAQVRSLEAQVAHADQQLR 1695
Cdd:TIGR02169  913 EKKRKRLSELKAKLEALEEELSEIEDPKG 941
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
647-1197 1.93e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 66.22  E-value: 1.93e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  647 ELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEqlqalkeslkvTKGSLEEEKRRAA 726
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRE-----------TIAETEREREELA 278
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  727 DALEEQQRCISELKAETRSLVEQhkqeqkeLEEEKAGRKGLEARLQQLgeahQAETEALRQELAEAIAAQRTAESECEQL 806
Cdd:PRK02224   279 EEVRDLRERLEELEEERDDLLAE-------AGLDDADAEAVEARREEL----EDRDEELRDRLEECRVAAQAHNEEAESL 347
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  807 VKEVAAWRERYEESQQEEAqygamfqeqlmTLKEECEKARQELQEAKEKVAGIEShselqisrqqnELVELHANLARALQ 886
Cdd:PRK02224   348 REDADDLEERAEELREEAA-----------ELESELEEAREAVEDRREEIEELEE-----------EIEELRERFGDAPV 405
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  887 QVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPArAGDREPEWLEEQQGRQfCSTQAA 966
Cdd:PRK02224   406 DLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPV-EGSPHVETIEEDRERV-EELEAE 483
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  967 LQAMEREAEQMGNELERLRAAlmesqgqqqeerGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQnALNEQRVEFA 1046
Cdd:PRK02224   484 LEDLEEEVEEVEERLERAEDL------------VEAEDRIERLEERREDLEELIAERRETIEEKRERAE-ELRERAAELE 550
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1047 TLQEALAHALTEKEGKDQElvklrglEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALR 1126
Cdd:PRK02224   551 AEAEEKREAAAEAEEEAEE-------AREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELND 623
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622865008 1127 AEVSKLEQQCQQQQEQADSLERS-LEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRT 1197
Cdd:PRK02224   624 ERRERLAEKRERKRELEAEFDEArIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEE 695
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
1219-1571 3.25e-10

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 65.53  E-value: 3.25e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1219 EAERKNSLISSLEEEVSILNRQVLEKeGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLR 1298
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEK-FEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAME 345
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1299 EEAEKQRVASENLRQELtsQAERAEELGQELKAWQEkffqkeqaLSTLQLEHTSTQALVSELLPAkhlcqqlqaeqaAAE 1378
Cdd:pfam17380  346 RERELERIRQEERKREL--ERIRQEEIAMEISRMRE--------LERLQMERQQKNERVRQELEA------------ARK 403
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1379 KRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML-------KKAHGLLAEEN 1451
Cdd:pfam17380  404 VKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLrqqeeerKRKKLELEKEK 483
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1452 RGLGERANLGRQFLEVELDQAREKYVQElaavraDAETRLAEVQREAQSTA--RELEVMTAKYEGAKVKVLEERQRFQEE 1529
Cdd:pfam17380  484 RDRKRAEEQRRKILEKELEERKQAMIEE------ERKRKLLEKEMEERQKAiyEEERRREAEEERRKQQEMEERRRIQEQ 557
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1622865008 1530 KQKLTAQVEQLEVFQREQ--TKQVEELRKKLADSDQASKVQQQK 1571
Cdd:pfam17380  558 MRKATEERSRLEAMERERemMRQIVESEKARAEYEATTPITTIK 601
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
460-1101 4.95e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.94  E-value: 4.95e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  460 EKQQLSSLIANLQSSISNLSQAKEELEQASQahgarltaQVASLTsELTTLNATIQQQDQELADLKQQAKE-EQAQLAQT 538
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALEDARE--------QIELLE-PIRELAERYAAARERLAELEYLRAAlRLWFAQRR 289
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  539 LQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQqlataaeereASLRERDAALQQLEALEKEKA---A 615
Cdd:COG4913    290 LELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG----------NGGDRLEQLEREIERLERELEereR 359
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  616 KLEILQQQLQV----ANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQS-EQQKATEK 690
Cdd:COG4913    360 RRARLEALLAAlglpLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASlERRKSNIP 439
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  691 ERVAQEKDQLQEQLQALKESLK-----VTKGSLEEEKRRAADAL----------EEQQ-----RCISELKAETRSLVEQH 750
Cdd:COG4913    440 ARLLALRDALAEALGLDEAELPfvgelIEVRPEEERWRGAIERVlggfaltllvPPEHyaaalRWVNRLHLRGRLVYERV 519
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  751 KQEQKELEEEKAGRKGLEARLQqlGEAHQAeTEALRQELAEAIAAqRTAESEcEQLVKE---------VAAWRERYE--- 818
Cdd:COG4913    520 RTGLPDPERPRLDPDSLAGKLD--FKPHPF-RAWLEAELGRRFDY-VCVDSP-EELRRHpraitragqVKGNGTRHEkdd 594
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  819 -ESQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAgieshselQISRQQNELVELHANLARaLQQVQEKEVRAQK 897
Cdd:COG4913    595 rRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLE--------ALEAELDALQERREALQR-LAEYSWDEIDVAS 665
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  898 LADDLSTLQEKMA---ATSKEVARLETLVRKAGEQQETASRELVKEPARAGDREPEW--LEEQqgrqfcstQAALQAMER 972
Cdd:COG4913    666 AEREIAELEAELErldASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELeqAEEE--------LDELQDRLE 737
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  973 EAEQMGNELERLRAalmESQGQQQEERGQQEREVARLTQERGRAQADLAlekaakaelemRLQNALNEQRVEFATLQEAL 1052
Cdd:COG4913    738 AAEDLARLELRALL---EERFAAALGDAVERELRENLEERIDALRARLN-----------RAEEELERAMRAFNREWPAE 803
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1053 AHAL-TEKEGKDQELVKLRGLEAAqikELEELRQTMKQLKEQLAKKEKEH 1101
Cdd:COG4913    804 TADLdADLESLPEYLALLDRLEED---GLPEYEERFKELLNENSIEFVAD 850
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
327-1112 7.14e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.75  E-value: 7.14e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  327 LREFASHLQQLQDALNELTEEHSRatQEWLEKQAQLekELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQE-- 404
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELHEK--QKFYLRQSVI--DLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEle 155
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  405 -----KGEVLGDV-LQLETLKQeaatLAANNTQLQARVETLETEQGQQEAKLLAERD-----HFEEEKQQLSSLIANLQS 473
Cdd:pfam15921  156 aakclKEDMLEDSnTQIEQLRK----MMLSHEGVLQEIRSILVDFEEASGKKIYEHDsmstmHFRSLGSAISKILRELDT 231
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  474 SISNL---------------SQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQT 538
Cdd:pfam15921  232 EISYLkgrifpvedqlealkSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQ 311
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  539 LQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRER---DAALQQLEALEKEKAA 615
Cdd:pfam15921  312 NSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESgnlDDQLQKLLADLHKREK 391
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  616 KLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETAcreQHEAQAQvaeLEFQLQSEQQKATEKERVAQ 695
Cdd:pfam15921  392 ELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAM---KSECQGQ---MERQMAAIQGKNESLEKVSS 465
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  696 EKDQLQ---EQLQALKESLKVTKGSLEEEKRRAAD---ALEEQQRCISELKAETRSLveqhkqeqkeleeekagRKGLEA 769
Cdd:pfam15921  466 LTAQLEstkEMLRKVVEELTAKKMTLESSERTVSDltaSLQEKERAIEATNAEITKL-----------------RSRVDL 528
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  770 RLQQLGEAH---------QAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQygamfqeqlmtLKE 840
Cdd:pfam15921  529 KLQELQHLKnegdhlrnvQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQ-----------LEK 597
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  841 ECEKARQELQE---AKEKVAGIESHSELQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVA 917
Cdd:pfam15921  598 EINDRRLELQEfkiLKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE 677
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  918 RLETLVRKAGEQQETASRELVK---------EPARAGDREPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAAL 988
Cdd:pfam15921  678 VLKRNFRNKSEEMETTTNKLKMqlksaqselEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAM 757
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  989 MESQGQQ---QEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQN---ALNEQRVEFATLQEALahaltekEGK 1062
Cdd:pfam15921  758 TNANKEKhflKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANmevALDKASLQFAECQDII-------QRQ 830
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622865008 1063 DQELVKLRGLEAAQIKELE----ELRQTMKQLKEQLAKKEKEHASGSGAQSEAA 1112
Cdd:pfam15921  831 EQESVRLKLQHTLDVKELQgpgyTSNSSMKPRLLQPASFTRTHSNVPSSQSTAS 884
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1470-1711 8.64e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 8.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1470 DQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEEKQKLTAQVEQLevfqREQTK 1549
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLA 295
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1550 QVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKthyDAKKQQNQ 1629
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE---EALLEAEA 372
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1630 ELQEQLQSLEHLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKS 1709
Cdd:COG1196    373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                   ..
gi 1622865008 1710 RE 1711
Cdd:COG1196    453 EL 454
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
335-828 1.04e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.91  E-value: 1.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  335 QQLQDALNELTEEHSRATQEWLEKQAQLEKELSTALQDKKCLEEKNEILQgKLSQLEEHLALLRENPPQEKGEVLGDVLQ 414
Cdd:PRK02224   202 KDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE-ELETLEAEIEDLRETIAETEREREELAEE 280
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  415 LETLKQEAATLAANNTQLqarVETLETEQGQQEAkLLAERDHFEEEKQQLSSLIANLQSSISNL-SQAKEELEQASQAHG 493
Cdd:PRK02224   281 VRDLRERLEELEEERDDL---LAEAGLDDADAEA-VEARREELEDRDEELRDRLEECRVAAQAHnEEAESLREDADDLEE 356
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  494 --ARLTAQVASLTSELTTLNATIQQQDQELADLKQQ----------AKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLK 561
Cdd:PRK02224   357 raEELREEAAELESELEEAREAVEDRREEIEELEEEieelrerfgdAPVDLGNAEDFLEELREERDELREREAELEATLR 436
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  562 QKEQQLKEVAE----------KQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEK--EKAAKLEILQQQLQVANE 629
Cdd:PRK02224   437 TARERVEEAEAlleagkcpecGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEErlERAEDLVEAEDRIERLEE 516
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  630 TRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKE 709
Cdd:PRK02224   517 RREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRT 596
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  710 SLKVTKGSLEE-----EKRRAADALEEQQR-CISELKAETRSLVEQHKQEQKELEEEKagRKGLEARLQQLGEAHQAETE 783
Cdd:PRK02224   597 LLAAIADAEDEierlrEKREALAELNDERReRLAEKRERKRELEAEFDEARIEEARED--KERAEEYLEQVEEKLDELRE 674
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622865008  784 AlRQELAEAIAAQRTAESECEQLVKEVAAWRER-------YEESQQEEAQYG 828
Cdd:PRK02224   675 E-RDDLQAEIGAVENELEELEELRERREALENRvealealYDEAEELESMYG 725
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
431-928 1.05e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 63.63  E-value: 1.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  431 QLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEqasqahgaRLTAQVASLTSELTTL 510
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELE--------ELEAELEELREELEKL 121
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  511 NATIQQQD--QELADLKQQAKEEQAQLAQTLQQQEQASQgLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATA 588
Cdd:COG4717    122 EKLLQLLPlyQELEALEAELAELPERLEELEERLEELRE-LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  589 AEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQrekAELSQKVEELRARVETACREQHE 668
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLI---AAALLALLGLGGSLLSLILTIAG 277
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  669 AQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQAL-KESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLV 747
Cdd:COG4717    278 VLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELeEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  748 EQHKQEQkeleeekagRKGLEARLQQLGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAwrERYEESQQEEAQY 827
Cdd:COG4717    358 ELEEELQ---------LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEE--LLGELEELLEALD 426
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  828 GAMFQEQLMTLKEECEKARQELQEAKEKVAGIEshSELQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQE 907
Cdd:COG4717    427 EEELEEELEELEEELEELEEELEELREELAELE--AELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEE 504
                          490       500
                   ....*....|....*....|.
gi 1622865008  908 KMAATSKEvaRLETLVRKAGE 928
Cdd:COG4717    505 AREEYREE--RLPPVLERASE 523
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
278-857 1.12e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.78  E-value: 1.12e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  278 LEELRDKNESLTmRLHETLKQCQDLKTE-KSQMDRKISQLLEEngdlsfKLREFASHLQQLQDALNELTEEHSRATQEWL 356
Cdd:COG4913    254 LEPIRELAERYA-AARERLAELEYLRAAlRLWFAQRRLELLEA------ELEELRAELARLEAELERLEARLDALREELD 326
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  357 EKQAQLE----KELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQEKGEvlgdvlqLETLKQEAATLAANNTQL 432
Cdd:COG4913    327 ELEAQIRgnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEE-------FAALRAEAAALLEALEEE 399
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  433 QARVETLETEQGQQEAKLlaerdhfEEEKQQLSSLIANLQSSISNLS----QAKEELEQASQA----------------- 491
Cdd:COG4913    400 LEALEEALAEAEAALRDL-------RRELRELEAEIASLERRKSNIParllALRDALAEALGLdeaelpfvgelievrpe 472
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  492 ------------HGARLT--------AQVASLTSEL-TTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLR 550
Cdd:COG4913    473 eerwrgaiervlGGFALTllvppehyAAALRWVNRLhLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLE 552
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  551 HQVEQLSSSLK-QKEQQLKEVAE--------KQEVTRRDH----------------AQQLATAAEEREASLRERDAALQQ 605
Cdd:COG4913    553 AELGRRFDYVCvDSPEELRRHPRaitragqvKGNGTRHEKddrrrirsryvlgfdnRAKLAALEAELAELEEELAEAEER 632
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  606 LEALEKEKAAkleiLQQQLQVAN--ETRDSAQTSVTQAQREKAELSQKVEELRArvetacreqheAQAQVAELEFQLqse 683
Cdd:COG4913    633 LEALEAELDA----LQERREALQrlAEYSWDEIDVASAEREIAELEAELERLDA-----------SSDDLAALEEQL--- 694
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  684 qqkatekERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAG 763
Cdd:COG4913    695 -------EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVEREL 767
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  764 RKGLEARLQQLGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEE-AQYGAMFQEQLMTLKEE- 841
Cdd:COG4913    768 RENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGlPEYEERFKELLNENSIEf 847
                          650       660
                   ....*....|....*....|
gi 1622865008  842 ----CEKARQELQEAKEKVA 857
Cdd:COG4913    848 vadlLSKLRRAIREIKERID 867
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
242-750 1.13e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 63.98  E-value: 1.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  242 KLLTEKDAQIAMMQQRI----DRL-ALLNEKQAASPLEPRE----LEELRDKNESLTMRLHETLKQCQDLKTE-KSQMDR 311
Cdd:pfam15921  224 KILRELDTEISYLKGRIfpveDQLeALKSESQNKIELLLQQhqdrIEQLISEHEVEITGLTEKASSARSQANSiQSQLEI 303
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  312 KISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEwLEKQAQL-EKELSTAL-------QDKKCLEEKNEIL 383
Cdd:pfam15921  304 IQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEE-LEKQLVLaNSELTEARterdqfsQESGNLDDQLQKL 382
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  384 QGKLSQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETE-QGQQEAKLLAERDHfEEEKQ 462
Cdd:pfam15921  383 LADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMAAIQGK-NESLE 461
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  463 QLSSLIANLQSSISNLSQAKEELE------QASQAHGARLTAQ-------VASLTSELTTLNATIQQQDQELADLK---- 525
Cdd:pfam15921  462 KVSSLTAQLESTKEMLRKVVEELTakkmtlESSERTVSDLTASlqekeraIEATNAEITKLRSRVDLKLQELQHLKnegd 541
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  526 --QQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKE------QQLKEVAEKQEVTRRDHAQQLATAAEEREASLR 597
Cdd:pfam15921  542 hlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGrtagamQVEKAQLEKEINDRRLELQEFKILKDKKDAKIR 621
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  598 ERDAALQQLEaLEKEKA--AKLEILQQQLQVANEtRDSAQTSVTQAQREKAELSQKVEELRARVETacrEQHEAQAQVAE 675
Cdd:pfam15921  622 ELEARVSDLE-LEKVKLvnAGSERLRAVKDIKQE-RDQLLNEVKTSRNELNSLSEDYEVLKRNFRN---KSEEMETTTNK 696
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622865008  676 LEFQLQSEQQKatekerVAQEKDQLQEQLQALKESLKVTKGSLEE--EKRRAADALEEQQRCISElkAETRSLVEQH 750
Cdd:pfam15921  697 LKMQLKSAQSE------LEQTRNTLKSMEGSDGHAMKVAMGMQKQitAKRGQIDALQSKIQFLEE--AMTNANKEKH 765
PTZ00121 PTZ00121
MAEBL; Provisional
1237-1719 1.33e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 1.33e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1237 LNRQVLEKEGESKELKRLVMAESEKSQKLED--RLRLLQAETASNSARAAERSSALR--EEVQSLRE--EAEKQRVASEN 1310
Cdd:PTZ00121  1072 LKPSYKDFDFDAKEDNRADEATEEAFGKAEEakKTETGKAEEARKAEEAKKKAEDARkaEEARKAEDarKAEEARKAEDA 1151
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1311 LRQELTSQAERAEELGQELKAWQEKffQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREEL----- 1385
Cdd:PTZ00121  1152 KRVEIARKAEDARKAEEARKAEDAK--KAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKkaeav 1229
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1386 ----EQSKQAAGGLRAELLRAQRELGELIPLRqkVAEQERTAQQLRAEKASYAEQLSM---LKKAHGLL-AEENRGLGE- 1456
Cdd:PTZ00121  1230 kkaeEAKKDAEEAKKAEEERNNEEIRKFEEAR--MAHFARRQAAIKAEEARKADELKKaeeKKKADEAKkAEEKKKADEa 1307
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1457 --RANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQR-EAQSTARELEVMTAKYEGAKVKVLEERQRFQEEKQKl 1533
Cdd:PTZ00121  1308 kkKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKaEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK- 1386
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1534 taqveqlevfqREQTKQVEELRKKlADSDQASKVQQQKLKAVQAQGGESQQEAQRLQaRLNELQAQLSQKEQAAEHYKLQ 1613
Cdd:PTZ00121  1387 -----------AEEKKKADEAKKK-AEEDKKKADELKKAAAAKKKADEAKKKAEEKK-KADEAKKKAEEAKKADEAKKKA 1453
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1614 MEKAKTHYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERlghelqqaglKTKEAEQTCRHLTAQVRSLEAQVAHADQQ 1693
Cdd:PTZ00121  1454 EEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEE----------AKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
                          490       500
                   ....*....|....*....|....*.
gi 1622865008 1694 LRDLGKFQVATDALKSREPQAKPQLD 1719
Cdd:PTZ00121  1524 ADEAKKAEEAKKADEAKKAEEKKKAD 1549
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
305-890 2.06e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.01  E-value: 2.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  305 EKSQMDRKISQLLEENGDLSfKLREFASHLQQLQDALNELTEEHSRATQEWLEKQAQleKELSTALQDKKcLEEKNEILQ 384
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLE-RAHEALEDAREQIELLEPIRELAERYAAARERLAEL--EYLRAALRLWF-AQRRLELLE 294
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  385 GKLSQLEEHLALLREnppqekgevlgdvlQLETLKQEAATLAANNTQLQARvetLETEQGQQEAKLLAERDHFEEEKQQL 464
Cdd:COG4913    295 AELEELRAELARLEA--------------ELERLEARLDALREELDELEAQ---IRGNGGDRLEQLEREIERLERELEER 357
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  465 SSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQ 544
Cdd:COG4913    358 ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  545 ASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRD-----------------------HAQQLATAAEEREASLR---- 597
Cdd:COG4913    438 IPARLLALRDALAEALGLDEAELPFVGELIEVRPEEerwrgaiervlggfaltllvppeHYAAALRWVNRLHLRGRlvye 517
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  598 ---ERDAALQQLEALEKEKAAKLEI--------LQQQLQ-------VANETR-DSAQTSVTQ------------------ 640
Cdd:COG4913    518 rvrTGLPDPERPRLDPDSLAGKLDFkphpfrawLEAELGrrfdyvcVDSPEElRRHPRAITRagqvkgngtrhekddrrr 597
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  641 ----------AQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKER------VAQEKDQLQEQL 704
Cdd:COG4913    598 irsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDeidvasAEREIAELEAEL 677
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  705 QALKES------LKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAG-----RKGLEARLQQ 773
Cdd:COG4913    678 ERLDASsddlaaLEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLarlelRALLEERFAA 757
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  774 LGEahQAETEALRQELAEAIAAQRTAESECE-QLVKEVAAWRERYEESQQE---EAQYGAMFQEQLMTLKEEcekarqEL 849
Cdd:COG4913    758 ALG--DAVERELRENLEERIDALRARLNRAEeELERAMRAFNREWPAETADldaDLESLPEYLALLDRLEED------GL 829
                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 1622865008  850 QEAKEKVAgieshsELQISRQQNELVELHANLARALQQVQE 890
Cdd:COG4913    830 PEYEERFK------ELLNENSIEFVADLLSKLRRAIREIKE 864
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
215-746 2.33e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 62.75  E-value: 2.33e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  215 QMRRLKKQLADERSNRDELELELAENRklltEKDAQIAMMQQRIDRLallNEKQAASPlepRELEELRDKNESLTMRLHE 294
Cdd:PRK02224   221 EIERYEEQREQARETRDEADEVLEEHE----ERREELETLEAEIEDL---RETIAETE---REREELAEEVRDLRERLEE 290
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  295 TLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRAT----------QEWLEKQAQLEK 364
Cdd:PRK02224   291 LEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLRedaddleeraEELREEAAELES 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  365 ELSTALQDKKCLEEKNEILQGKLSQLEE--------------HLALLREnppqEKGEVLGDVLQLETLKQEAATLAANNT 430
Cdd:PRK02224   371 ELEEAREAVEDRREEIEELEEEIEELRErfgdapvdlgnaedFLEELRE----ERDELREREAELEATLRTARERVEEAE 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  431 QLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHgarltAQVASLTSELTTL 510
Cdd:PRK02224   447 ALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE-----DRIERLEERREDL 521
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  511 NATIQQQDQELADLKQQAKEeqaqlaqtlqqqeqasqgLRHQVEQLSSSLKQKEqqlkEVAEKQEVTRRDHAQQLATAAE 590
Cdd:PRK02224   522 EELIAERRETIEEKRERAEE------------------LRERAAELEAEAEEKR----EAAAEAEEEAEEAREEVAELNS 579
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  591 EREaslrERDAALQQLEALEkEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQ 670
Cdd:PRK02224   580 KLA----ELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEARED 654
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622865008  671 AQVAElefqlqSEQQKATEK-ERVAQEKDQLQEQLQALKESLKvtkgSLEEEKRRaADALEEQQRCISELKAETRSL 746
Cdd:PRK02224   655 KERAE------EYLEQVEEKlDELREERDDLQAEIGAVENELE----ELEELRER-REALENRVEALEALYDEAEEL 720
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
220-1051 2.38e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.07  E-value: 2.38e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  220 KKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALlnEKQAASPLEPRELEELRDKNESLTMRLHETLKQC 299
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEE--EYLLYLDYLKLNEERIDLLQELLRDEQEEIESSK 257
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  300 QDLKTEKSQMDRKISQLLEENGDLSFKLREFASHlqqlqdalnelteehsratqewLEKQAQLEKELSTALQDKKCLEEK 379
Cdd:pfam02463  258 QEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLL----------------------AKEEEELKSELLKLERRKVDDEEK 315
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  380 NEILQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAErdhfEE 459
Cdd:pfam02463  316 LKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSA----AK 391
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  460 EKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNA--TIQQQDQELADLKQQAKEEQAQLAQ 537
Cdd:pfam02463  392 LKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGklTEEKEELEKQELKLLKDELELKKSE 471
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  538 TLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKL 617
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIV 551
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  618 EILQQQLQVanETRDSAQTSVTQAQREKAELSQ-----KVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKER 692
Cdd:pfam02463  552 EVSATADEV--EERQKLVRALTELPLGARKLRLlipklKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGIL 629
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  693 VAQEKDQLQEQLQALKESLK----VTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLE 768
Cdd:pfam02463  630 KDTELTKLKESAKAKESGLRkgvsLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  769 ARLQQLGEAHQaETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAMFQEQLMTLKEECEKARQE 848
Cdd:pfam02463  710 EELKKLKLEAE-ELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKV 788
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  849 LQEAKEKVAGIESHSELQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGE 928
Cdd:pfam02463  789 EEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL 868
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  929 QQETASRE----LVKEPARAGDREPEWLEEQQGRQFCSTQ--AALQAMEREAEQMGNELERLRAAL-MESQGQQQEERGQ 1001
Cdd:pfam02463  869 LQELLLKEeeleEQKLKDELESKEEKEKEEKKELEEESQKlnLLEEKENEIEERIKEEAEILLKYEeEPEELLLEEADEK 948
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1002 QEREVARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRVEFATLQEA 1051
Cdd:pfam02463  949 EKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
578-1429 2.66e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 62.66  E-value: 2.66e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  578 RRDHAQQLATAAEEREASLRERDAALQQLEALEKE---KAAKLEILQQQLQVANETRDSAQTSVtqAQREKAELSQK-VE 653
Cdd:COG3096    280 RRELSERALELRRELFGARRQLAEEQYRLVEMAREleeLSARESDLEQDYQAASDHLNLVQTAL--RQQEKIERYQEdLE 357
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  654 ELRARVEtacreqhEAQAQVAELEFQLQSEQqkaTEKERVAQEKDQLQEQLQALKESLkvtkgslEEEKRRA------AD 727
Cdd:COG3096    358 ELTERLE-------EQEEVVEEAAEQLAEAE---ARLEAAEEEVDSLKSQLADYQQAL-------DVQQTRAiqyqqaVQ 420
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  728 ALEEQQRC--ISELKAEtrslveqhkqeqkeleeekagrkGLEARLQQLGEAHQAETE---ALRQELAEAIAAQRTAEsE 802
Cdd:COG3096    421 ALEKARALcgLPDLTPE-----------------------NAEDYLAAFRAKEQQATEevlELEQKLSVADAARRQFE-K 476
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  803 CEQLVKEVAAWRERYEESQQeeaqygamfqeqlmtlkeecekARQELQEAKEKVAGIESHSelQISRQQNELVELHANLA 882
Cdd:COG3096    477 AYELVCKIAGEVERSQAWQT----------------------ARELLRRYRSQQALAQRLQ--QLRAQLAELEQRLRQQQ 532
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  883 RALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARA---GDREPEW-------- 951
Cdd:COG3096    533 NAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIkelAARAPAWlaaqdale 612
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  952 -LEEQQGRQFCSTQAALQAM------EREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERG-----RAQAD 1019
Cdd:COG3096    613 rLREQSGEALADSQEVTAAMqqllerEREATVERDELAARKQALESQIERLSQPGGAEDPRLLALAERLGgvllsEIYDD 692
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1020 LALEKAAkaELEMRLQNA--------LNEQRVEFATLQEAL--------------AHALTEKEGKDQELVKLRGLE---- 1073
Cdd:COG3096    693 VTLEDAP--YFSALYGPArhaivvpdLSAVKEQLAGLEDCPedlyliegdpdsfdDSVFDAEELEDAVVVKLSDRQwrys 770
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1074 ----------AAQIKELEELRQTMKQLKEQLA-------KKEKEHASGS---GAQSEAAGRTEPTgPKLEALRAEVSKle 1133
Cdd:COG3096    771 rfpevplfgrAAREKRLEELRAERDELAEQYAkasfdvqKLQRLHQAFSqfvGGHLAVAFAPDPE-AELAALRQRRSE-- 847
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1134 qqcqqqqeqadsLERSLEAERASRAERDSALETLQGQLEEKARELGHSqSALAsvQRELAALRTKVQDHSKAEDEWKAQV 1213
Cdd:COG3096    848 ------------LERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQA-NLLA--DETLADRLEELREELDAAQEAQAFI 912
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1214 ARGRQEAERKNSLISSLE---EEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEdrlrllqAETASNSARAAERSSAL 1290
Cdd:COG3096    913 QQHGKALAQLEPLVAVLQsdpEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRP-------HFSYEDAVGLLGENSDL 985
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1291 REEVQSLREEAEKQRvasenlrqeltsqaeraEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPA-KHLCQQ 1369
Cdd:COG3096    986 NEKLRARLEQAEEAR-----------------REAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQElEELGVQ 1048
                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622865008 1370 LQAEQAAAEKRHREELEQSKQAAGGLRAELLRA-QRELGELIPLRQKVAEQERTAQQLRAE 1429
Cdd:COG3096   1049 ADAEAEERARIRRDELHEELSQNRSRRSQLEKQlTRCEAEMDSLQKRLRKAERDYKQEREQ 1109
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1239-1692 3.14e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.63  E-value: 3.14e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1239 RQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAE-TASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTS 1317
Cdd:COG4913    241 HEALEDAREQIELLEPIRELAERYAAARERLAELEYLrAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDA 320
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1318 QAERAEEL--------GQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELlpakhlcQQLQAEQAAAEKRHREELEQSK 1389
Cdd:COG4913    321 LREELDELeaqirgngGDRLEQLEREIERLERELEERERRRARLEALLAAL-------GLPLPASAEEFAALRAEAAALL 393
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1390 QAAGGLRAELLRAQRELG-ELIPLRQKVAEQERTAQQLRAEKASYAEQL----SMLKKAHGLLAEENRGLGEranlgrqF 1464
Cdd:COG4913    394 EALEEELEALEEALAEAEaALRDLRRELRELEAEIASLERRKSNIPARLlalrDALAEALGLDEAELPFVGE-------L 466
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1465 LEVELDQAR--------------------EKYVQELAAVRA----------DAETRLAEVQR---EAQSTARELEVMTAK 1511
Cdd:COG4913    467 IEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVNRlhlrgrlvyeRVRTGLPDPERprlDPDSLAGKLDFKPHP 546
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1512 YEGAKVKVLEERQRFqeekqkltAQVEQLEVFQRE--------QTKQVEELRKKLADSDQASKVQ-----QQKLKAVQAQ 1578
Cdd:COG4913    547 FRAWLEAELGRRFDY--------VCVDSPEELRRHpraitragQVKGNGTRHEKDDRRRIRSRYVlgfdnRAKLAALEAE 618
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1579 GGESQQEAQRLQARLNELQAQLSQKEQAAEHYK---------LQMEKAKTHYDAKKQQNQELQEQLQSLEHLQKENKELR 1649
Cdd:COG4913    619 LAELEEELAEAEERLEALEAELDALQERREALQrlaeyswdeIDVASAEREIAELEAELERLDASSDDLAALEEQLEELE 698
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 1622865008 1650 AEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ 1692
Cdd:COG4913    699 AELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAED 741
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
772-1329 3.28e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.24  E-value: 3.28e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  772 QQLGEAHQAETEALRQ--------ELAEAIAAQRTAESECEQLVKEVAAWR--ERYEESQQEEAQygamFQEQLMTLKEE 841
Cdd:COG4913    235 DDLERAHEALEDAREQiellepirELAERYAAARERLAELEYLRAALRLWFaqRRLELLEAELEE----LRAELARLEAE 310
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  842 CEKARQELQEAKEKVAgieshsELQISRQQN---ELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVAR 918
Cdd:COG4913    311 LERLEARLDALREELD------ELEAQIRGNggdRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAA 384
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  919 LETLVRKAGEQQETASRELVKEPARAGDREpewleEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALmesqGQQQEE 998
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAAL-----RDLRRELRELEAEIASLERRKSNIPARLLALRDAL----AEALGL 455
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  999 RGQQEREVA-----RLTQERGRAQADLAL-------------EKAAKAELE-MRLQNALNEQRVEFATLQEA-------- 1051
Cdd:COG4913    456 DEAELPFVGelievRPEEERWRGAIERVLggfaltllvppehYAAALRWVNrLHLRGRLVYERVRTGLPDPErprldpds 535
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1052 LAHALTEKEGKDQELVK---LRGLEAAQIKELEELRQT---------MKQLKEQLAKKEKEHASGS---GAQSEAagrte 1116
Cdd:COG4913    536 LAGKLDFKPHPFRAWLEaelGRRFDYVCVDSPEELRRHpraitragqVKGNGTRHEKDDRRRIRSRyvlGFDNRA----- 610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1117 ptgpKLEALRAEVSKLEQQCQQqqeqADSLERSLEAERASRAERDSALETLQGQLEEkarelghsQSALASVQRELAALR 1196
Cdd:COG4913    611 ----KLAALEAELAELEEELAE----AEERLEALEAELDALQERREALQRLAEYSWD--------EIDVASAEREIAELE 674
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1197 TKvqdhskaedewkaqvargRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAET 1276
Cdd:COG4913    675 AE------------------LERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRL 736
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622865008 1277 ASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQEL 1329
Cdd:COG4913    737 EAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
391-806 3.31e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 62.66  E-value: 3.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  391 EEHLALLREnppqekgevlgdvlQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDhfEEEKQQLSSLIAN 470
Cdd:COG3096    784 EKRLEELRA--------------ERDELAEQYAKASFDVQKLQRLHQAFSQFVGGHLAVAFAPDP--EAELAALRQRRSE 847
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  471 LQSSISNLSQAKEELEQASQAHGARLtAQVASLTSELTTLNatiqqqDQELADLKQQAKEEQAQLAQTLQQQEQASQGLR 550
Cdd:COG3096    848 LERELAQHRAQEQQLRQQLDQLKEQL-QLLNKLLPQANLLA------DETLADRLEELREELDAAQEAQAFIQQHGKALA 920
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  551 hQVEQLSSSLKQKEQQLKEVaeKQEVTRRDHAQQLATAAEEREASLRERDAAL--QQLEALEKEKAAKLEILQQQLQVAN 628
Cdd:COG3096    921 -QLEPLVAVLQSDPEQFEQL--QADYLQAKEQQRRLKQQIFALSEVVQRRPHFsyEDAVGLLGENSDLNEKLRARLEQAE 997
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  629 ETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQkatekERVAQEKDQLQEQLQAL- 707
Cdd:COG3096    998 EARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAE-----ERARIRRDELHEELSQNr 1072
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  708 --KESLKVTKGSLEEEKRRAADALEEQQRcisELKAEtRSLVEQHKQEQKELEEEKAGRkGLEARLQQLGEAHQaETEAL 785
Cdd:COG3096   1073 srRSQLEKQLTRCEAEMDSLQKRLRKAER---DYKQE-REQVVQAKAGWCAVLRLARDN-DVERRLHRRELAYL-SADEL 1146
                          410       420
                   ....*....|....*....|.
gi 1622865008  786 RQELAEAIAAQRTAESECEQL 806
Cdd:COG3096   1147 RSMSDKALGALRLAVADNEHL 1167
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1060-1665 3.50e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.39  E-value: 3.50e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1060 EGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQ 1139
Cdd:PRK03918   161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI 240
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1140 QeqadslerSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAE---DEWKAQVARG 1216
Cdd:PRK03918   241 E--------ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSefyEEYLDELREI 312
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1217 RQEAERKNSLISSLEEEVSILNrqvlEKEGESKELKrlvmaesEKSQKLEDRLRLLQaetasNSARAAERSSALREEVQS 1296
Cdd:PRK03918   313 EKRLSRLEEEINGIEERIKELE----EKEERLEELK-------KKLKELEKRLEELE-----ERHELYEEAKAKKEELER 376
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1297 LREEAEKQRVasENLRQELTSQAERAEELGQELKAWQEKffqkeqaLSTLQLEHTSTQALVSELLPAKHLC-----QQLQ 1371
Cdd:PRK03918   377 LKKRLTGLTP--EKLEKELEELEKAKEEIEEEISKITAR-------IGELKKEIKELKKAIEELKKAKGKCpvcgrELTE 447
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1372 AEQAAAEKRHREEL---EQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAE-QLSMLKKAhgll 1447
Cdd:PRK03918   448 EHRKELLEEYTAELkriEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKyNLEELEKK---- 523
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1448 AEENRGLGERAN-LGRQFLEVELDQAREKyvqELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRF 1526
Cdd:PRK03918   524 AEEYEKLKEKLIkLKGEIKSLKKELEKLE---ELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPF 600
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1527 QEEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGE-SQQEAQRLQARLNELQAQLSQKEQ 1605
Cdd:PRK03918   601 YNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKySEEEYEELREEYLELSRELAGLRA 680
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622865008 1606 AAEHYKLQMEKAKTHYD---AKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQAGLK 1665
Cdd:PRK03918   681 ELEELEKRREEIKKTLEklkEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALS 743
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
414-990 5.59e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 5.59e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  414 QLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAER-DHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAH 492
Cdd:COG4913    256 PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRGN 335
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  493 GARltaQVASLTSELTTLNATIQQQDQELADLKQQAKEeqaqlaqtlqqqeqasqgLRHQVEQLSSSLKQKEQQLKEVAE 572
Cdd:COG4913    336 GGD---RLEQLEREIERLERELEERERRRARLEALLAA------------------LGLPLPASAEEFAALRAEAAALLE 394
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  573 KQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEK---AAKLEILQQQLqvanetrdSAQTSVTQAQ-REKAEL 648
Cdd:COG4913    395 ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsniPARLLALRDAL--------AEALGLDEAElPFVGEL 466
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  649 SQ-KVEELRAR--VETACR---------EQHEAQAQVA------ELEFQLQSEQQKATEKERVAQEKDQLQEQLqalkeS 710
Cdd:COG4913    467 IEvRPEEERWRgaIERVLGgfaltllvpPEHYAAALRWvnrlhlRGRLVYERVRTGLPDPERPRLDPDSLAGKL-----D 541
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  711 LKVTK--GSLEEEKRRAADAleeqqRC---ISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLqQLGEAHQAETEAL 785
Cdd:COG4913    542 FKPHPfrAWLEAELGRRFDY-----VCvdsPEELRRHPRAITRAGQVKGNGTRHEKDDRRRIRSRY-VLGFDNRAKLAAL 615
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  786 RQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQeeaqygamfqeqlmtlkeecekaRQELQEAKEKVAGIEShsel 865
Cdd:COG4913    616 EAELAELEEELAEAEERLEALEAELDALQERREALQR-----------------------LAEYSWDEIDVASAER---- 668
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  866 QISRQQNELVELHAN---LARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPA 942
Cdd:COG4913    669 EIAELEAELERLDASsddLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR 748
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1622865008  943 RAGDrepEWLEEQQGRQfcSTQAALQAMEREAEQMGNELERLRAALME 990
Cdd:COG4913    749 ALLE---ERFAAALGDA--VERELRENLEERIDALRARLNRAEEELER 791
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
276-725 1.18e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 60.17  E-value: 1.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  276 RELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKISQL--LEENGDLSFKLREFASHLQQLQDALNELTEEHsratQ 353
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLekLLQLLPLYQELEALEAELAELPERLEELEERL----E 156
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  354 EWLEKQAQLEKelstalqdkkcleekneiLQGKLSQLEEHLA-LLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQL 432
Cdd:COG4717    157 ELRELEEELEE------------------LEAELAELQEELEeLLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA 218
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  433 QARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNA 512
Cdd:COG4717    219 QEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKA 298
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  513 TIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQ-----LAT 587
Cdd:COG4717    299 SLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQeiaalLAE 378
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  588 AAEEREASLRERDAALQQLEALEKEKAAkleiLQQQLQVANETRDSAqtsvtQAQREKAELSQKVEELRARVETACREQH 667
Cdd:COG4717    379 AGVEDEEELRAALEQAEEYQELKEELEE----LEEQLEELLGELEEL-----LEALDEEELEEELEELEEELEELEEELE 449
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622865008  668 EAQAQVAELEFQLQsEQQKATEKERVAQEKDQLQEQLQALKE---SLKVTKGSLEEEKRRA 725
Cdd:COG4717    450 ELREELAELEAELE-QLEEDGELAELLQELEELKAELRELAEewaALKLALELLEEAREEY 509
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1008-1331 1.57e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1008 RLTQERGRAQADLALEKAAKAELEMRLQnALNEQRVEFATLQEALAHALTEKEGKDQELVKLR----------------- 1070
Cdd:PRK02224   224 RYEEQREQARETRDEADEVLEEHEERRE-ELETLEAEIEDLRETIAETEREREELAEEVRDLRerleeleeerddllaea 302
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1071 GLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAgrteptgpklEALRAEVSKLEQQCQQQQEQADSLERSL 1150
Cdd:PRK02224   303 GLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEA----------ESLREDADDLEERAEELREEAAELESEL 372
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1151 EAERASRAERDSALETLQGQLEEKAR-------ELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQ----- 1218
Cdd:PRK02224   373 EEAREAVEDRREEIEELEEEIEELRErfgdapvDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAlleag 452
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1219 ----------------EAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRL--LQAETASNS 1280
Cdd:PRK02224   453 kcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLeeLIAERRETI 532
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622865008 1281 ARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKA 1331
Cdd:PRK02224   533 EEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAE 583
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1075-1662 1.84e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 1.84e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1075 AQIKELEELRQTMKQLKEQLAKkekehasgsgaqseaagrteptgpkLEALRAEVSKLEQQCQQQQEqADSLERSLEAER 1154
Cdd:COG4913    232 EHFDDLERAHEALEDAREQIEL-------------------------LEPIRELAERYAAARERLAE-LEYLRAALRLWF 285
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1155 ASR--AERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHS-KAEDEWKAQVARGRQEAERKNSLISSLE 1231
Cdd:COG4913    286 AQRrlELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLE 365
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1232 EEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENL 1311
Cdd:COG4913    366 ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLAL 445
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1312 RQELTSQAERAE----------ELGQELKAWQEKFfqkEQALSTLQLehtstqalvSELLPAKHLcqqlqaeqaaaekrh 1381
Cdd:COG4913    446 RDALAEALGLDEaelpfvgeliEVRPEEERWRGAI---ERVLGGFAL---------TLLVPPEHY--------------- 498
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1382 reeleqsKQAAGGLRAELLRAQrelgelipLR-QKVAEQERTAQQLRAEKASYAEQLSMlkKAHGLLAEENRGLGERANL 1460
Cdd:COG4913    499 -------AAALRWVNRLHLRGR--------LVyERVRTGLPDPERPRLDPDSLAGKLDF--KPHPFRAWLEAELGRRFDY 561
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1461 GRQFLEVELDQAR--------------------EKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVL 1520
Cdd:COG4913    562 VCVDSPEELRRHPraitragqvkgngtrhekddRRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELD 641
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1521 EERQRFQEEKQKLTAQVEQLEVfqREQTKQVEELRKKLADSDQAS----------KVQQQKLKAVQAQGGESQQEAQRLQ 1590
Cdd:COG4913    642 ALQERREALQRLAEYSWDEIDV--ASAEREIAELEAELERLDASSddlaaleeqlEELEAELEELEEELDELKGEIGRLE 719
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622865008 1591 ARLNELQAQLSQKEQAAEHY-KLQMEKAKTHYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQA 1662
Cdd:COG4913    720 KELEQAEEELDELQDRLEAAeDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
291-857 2.61e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.31  E-value: 2.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  291 RLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELteehsratQEWLEKQAQLEKELSTAL 370
Cdd:PRK03918   180 RLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL--------EELKEEIEELEKELESLE 251
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  371 QDKKCLEEKNEILQGKLSQLEEHLALLRENpPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLEtEQGQQEAKL 450
Cdd:PRK03918   252 GSKRKLEEKIRELEERIEELKKEIEELEEK-VKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLE-EEINGIEER 329
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  451 LAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQahgarLTAQVASLTSELTTLN-ATIQQQDQELADLKQQAK 529
Cdd:PRK03918   330 IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKA-----KKEELERLKKRLTGLTpEKLEKELEELEKAKEEIE 404
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  530 EEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQ--------KEQQLKEVAEKQEVTRRDHAQQLATaAEEREASLRERDA 601
Cdd:PRK03918   405 EEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYTAELKRIEKELKE-IEEKERKLRKELR 483
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  602 ALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEfqlQ 681
Cdd:PRK03918   484 ELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA---E 560
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  682 SEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRR---AADALEEQQRCISELKAETRSLVEQHKQEQKELE 758
Cdd:PRK03918   561 LEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEyleLKDAEKELEREEKELKKLEEELDKAFEELAETEK 640
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  759 EEKAGRKGLEARLQQLGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYgamfQEQLmtl 838
Cdd:PRK03918   641 RLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKA----KKEL--- 713
                          570
                   ....*....|....*....
gi 1622865008  839 kEECEKARQELQEAKEKVA 857
Cdd:PRK03918   714 -EKLEKALERVEELREKVK 731
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
215-745 3.22e-08

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 58.98  E-value: 3.22e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  215 QMRRLKKQLADE-RSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPRELEELRDKN-ESLTMRL 292
Cdd:pfam05557   13 QLQNEKKQMELEhKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYlEALNKKL 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  293 HETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEWLEKQAQLeKELSTALQD 372
Cdd:pfam05557   93 NEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQ-SSLAEAEQR 171
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  373 KKCLEEKNeilqgklsQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAA---TLAANNTQLQARVETLETEQGQQE-- 447
Cdd:pfam05557  172 IKELEFEI--------QSQEQDSEIVKNSKSELARIPELEKELERLREHNKhlnENIENKLLLKEEVEDLKRKLEREEky 243
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  448 ----AKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGArLTAQVASLTSELTTLNATIQQQDQELAD 523
Cdd:pfam05557  244 reeaATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQREIV-LKEENSSLTSSARQLEKARRELEQELAQ 322
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  524 LKQQAKEEQAQLAQTLQQQEQASQ----------GLRHQVEQLSSSLKQKEQQLKEVAEKQEVTrrDHAQQLATAAEERE 593
Cdd:pfam05557  323 YLKKIEDLNKKLKRHKALVRRLQRrvllltkerdGYRAILESYDKELTMSNYSPQLLERIEEAE--DMTQKMQAHNEEME 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  594 ASL----RERDAALQQLEALEKEkaakLEILQQQLQVANetrdsaqtsVTQAQREKAELSQKVEELRARVETACREQHEA 669
Cdd:pfam05557  401 AQLsvaeEELGGYKQQAQTLERE----LQALRQQESLAD---------PSYSKEEVDSLRRKLETLELERQRLREQKNEL 467
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  670 QAQVAELEFQLQSEQQK-----------ATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISE 738
Cdd:pfam05557  468 EMELERRCLQGDYDPKKtkvlhlsmnpaAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMNFKEVLD 547

                   ....*..
gi 1622865008  739 LKAETRS 745
Cdd:pfam05557  548 LRKELES 554
mukB PRK04863
chromosome partition protein MukB;
598-990 4.70e-08

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 58.82  E-value: 4.70e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  598 ERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELrARVETACREQHE---AQAQVA 674
Cdd:PRK04863   280 ERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKierYQADLE 358
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  675 ELEFQLQsEQQKATEKerVAQEKDQLQEQLQALKESLKVTKGSLEEEKRraadALEEQQrciselkaeTRSLVEQHKQEQ 754
Cdd:PRK04863   359 ELEERLE-EQNEVVEE--ADEQQEENEARAEAAEEEVDELKSQLADYQQ----ALDVQQ---------TRAIQYQQAVQA 422
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  755 KELEEEKAGR-----KGLEARLQQLGEAHQAETEALRQ-----ELAEAIAAQRTaesECEQLVKEVAAWRERyeesqqEE 824
Cdd:PRK04863   423 LERAKQLCGLpdltaDNAEDWLEEFQAKEQEATEELLSleqklSVAQAAHSQFE---QAYQLVRKIAGEVSR------SE 493
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  825 AQYGAmfqeqlmtlKEECEKARQELQEAkEKVAGIES-HSEL-QISRQQNELVELHANLARALQQVQEKEVRAQKLADDL 902
Cdd:PRK04863   494 AWDVA---------RELLRRLREQRHLA-EQLQQLRMrLSELeQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEEL 563
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  903 STLQEKMAATSKEVARLETLVRKAGEQQETASRELVKeparagdREPEWLE-----EQQGRQFCSTQAALQAMEreaEQM 977
Cdd:PRK04863   564 EARLESLSESVSEARERRMALRQQLEQLQARIQRLAA-------RAPAWLAaqdalARLREQSGEEFEDSQDVT---EYM 633
                          410
                   ....*....|...
gi 1622865008  978 GNELERLRAALME 990
Cdd:PRK04863   634 QQLLERERELTVE 646
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
334-781 5.14e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.24  E-value: 5.14e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  334 LQQLQDALNELTEEHSRATQEWLEKQAQLEKELSTALQDKKCLEEkneiLQGKLSQLEEHLALLRENPPQEKGEV--LGD 411
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAE----LQEELEELEEELEELEAELEELREELekLEK 123
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  412 VLQLETLKQEAATLAANNTQLQARVETLEtEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNlsQAKEELEQASQA 491
Cdd:COG4717    124 LLQLLPLYQELEALEAELAELPERLEELE-ERLEELRELEEELEELEAELAELQEELEELLEQLSL--ATEEELQDLAEE 200
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  492 HgARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVA 571
Cdd:COG4717    201 L-EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVL 279
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  572 --------------EKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTS 637
Cdd:COG4717    280 flvlgllallflllAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL 359
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  638 VTQAQREKAELSQK----------VEELRARVEtACREQHEAQAQVAELEFQLQS------EQQKATEKERVAQEKDQLQ 701
Cdd:COG4717    360 EEELQLEELEQEIAallaeagvedEEELRAALE-QAEEYQELKEELEELEEQLEEllgeleELLEALDEEELEEELEELE 438
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  702 EQLQALKESLKvtkgSLEEEKRRAADALE--EQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQ 779
Cdd:COG4717    439 EELEELEEELE----ELREELAELEAELEqlEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514

                   ..
gi 1622865008  780 AE 781
Cdd:COG4717    515 PP 516
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
443-678 7.62e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.08  E-value: 7.62e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  443 QGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASqahgARLTAQVASLTSELTTLNATIQQQDQELA 522
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI----AALARRIRALEQELAALEAELAELEKEIA 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  523 DLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVtRRDHAQQLATAAEEREASLRERDAA 602
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA-RREQAEELRADLAELAALRAELEAE 172
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622865008  603 LQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEF 678
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248
mukB PRK04863
chromosome partition protein MukB;
431-840 9.62e-08

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 57.66  E-value: 9.62e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  431 QLQARVETLETEQgqqeAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQahGARLTAQVASLTSELTTL 510
Cdd:PRK04863   294 ELYTSRRQLAAEQ----YRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEK--IERYQADLEELEERLEEQ 367
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  511 NATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLrhqveqlssslkqKEQQLKEVAEKQEVTRRDHAQQLATAAE 590
Cdd:PRK04863   368 NEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQAL-------------DVQQTRAIQYQQAVQALERAKQLCGLPD 434
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  591 EREASLRERdaaLQQLEALEKEKAAKLEILQQQLQVANETRD------------SAQTSVTQAQREKAELSQKVEELRAR 658
Cdd:PRK04863   435 LTADNAEDW---LEEFQAKEQEATEELLSLEQKLSVAQAAHSqfeqayqlvrkiAGEVSRSEAWDVARELLRRLREQRHL 511
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  659 VETAcreqHEAQAQVAELEFQLQSEQ---QKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRC 735
Cdd:PRK04863   512 AEQL----QQLRMRLSELEQRLRQQQraeRLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQ 587
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  736 ISELKAETRSLVEQHKQEQKeleeekagrkgLEARLQQLGEaHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRE 815
Cdd:PRK04863   588 LEQLQARIQRLAARAPAWLA-----------AQDALARLRE-QSGEEFEDSQDVTEYMQQLLERERELTVERDELAARKQ 655
                          410       420
                   ....*....|....*....|....*
gi 1622865008  816 RYEESQQEEAQYGAMFQEQLMTLKE 840
Cdd:PRK04863   656 ALDEEIERLSQPGGSEDPRLNALAE 680
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
216-530 1.59e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.57  E-value: 1.59e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  216 MRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAasplepRELEELRDKNESLTMRLHET 295
Cdd:TIGR04523  309 NKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQ------RELEEKQNEIEKLKKENQSY 382
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  296 LKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEW--LEKQ-AQLEKELSTALQD 372
Cdd:TIGR04523  383 KQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIkdLTNQdSVKELIIKNLDNT 462
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  373 KKCLEEKNEILQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLA 452
Cdd:TIGR04523  463 RESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISD 542
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  453 -----ERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQAS---QAHGARLTAQVASLTSELTTLNATIQQQDQELADL 524
Cdd:TIGR04523  543 ledelNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQeekQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKA 622

                   ....*.
gi 1622865008  525 KQQAKE 530
Cdd:TIGR04523  623 KKENEK 628
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
213-734 1.75e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  213 QFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRlallNEKQAASPLEpRELEELRDKNESLTMRL 292
Cdd:COG4913    287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG----NGGDRLEQLE-REIERLERELEERERRR 361
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  293 HETLKQCQDLKteksqmdrkisqlLEENGDLSfklrEFASHLQQLQDALNELTEEHSRATQEwlekQAQLEKELSTALQD 372
Cdd:COG4913    362 ARLEALLAALG-------------LPLPASAE----EFAALRAEAAALLEALEEELEALEEA----LAEAEAALRDLRRE 420
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  373 KKCLEEKNEILQGKLSQLEEHLALLRE------NPPQEKGEVLGDVLQLETL-----------------------KQEAA 423
Cdd:COG4913    421 LRELEAEIASLERRKSNIPARLLALRDalaealGLDEAELPFVGELIEVRPEeerwrgaiervlggfaltllvppEHYAA 500
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  424 TLAA-NNTQLQARVETLETEQGQQEAKLLAERDHfeeekqqlsSLIANLQSSISNLSQ-AKEELEQASQAHGARLTAQVA 501
Cdd:COG4913    501 ALRWvNRLHLRGRLVYERVRTGLPDPERPRLDPD---------SLAGKLDFKPHPFRAwLEAELGRRFDYVCVDSPEELR 571
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  502 ----SLTSE-LTTLNATIQQQD----------------QELADLKQQAKEeqaqlaqtlqqqeqasqgLRHQVEQLSSSL 560
Cdd:COG4913    572 rhprAITRAgQVKGNGTRHEKDdrrrirsryvlgfdnrAKLAALEAELAE------------------LEEELAEAEERL 633
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  561 KQKEQQLKEVAEkqevtRRDHAQQLATAAEER---EASLRERDAALQQLEALEKEKaAKLEILQQQLQVANETRDSAQTS 637
Cdd:COG4913    634 EALEAELDALQE-----RREALQRLAEYSWDEidvASAEREIAELEAELERLDASS-DDLAALEEQLEELEAELEELEEE 707
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  638 VTQAQREKAELSQKVEELRARVEtACREQHEA--QAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQAlkeslkvtk 715
Cdd:COG4913    708 LDELKGEIGRLEKELEQAEEELD-ELQDRLEAaeDLARLELRALLEERFAAALGDAVERELRENLEERIDA--------- 777
                          570
                   ....*....|....*....
gi 1622865008  716 gsLEEEKRRAADALEEQQR 734
Cdd:COG4913    778 --LRARLNRAEEELERAMR 794
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
582-816 1.89e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 1.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  582 AQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVET 661
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  662 ACREQHEAQAQVAELEFQLQS-----------EQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALE 730
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRlgrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  731 EQQRCISELKAETRSLveqhkqeqkelEEEKAGRKGLEARLQQlgeahqaETEALRQELAEAIAAQRTAESECEQLVKEV 810
Cdd:COG4942    175 ELEALLAELEEERAAL-----------EALKAERQKLLARLEK-------ELAELAAELAELQQEAEELEALIARLEAEA 236

                   ....*.
gi 1622865008  811 AAWRER 816
Cdd:COG4942    237 AAAAER 242
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
215-707 2.09e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.31  E-value: 2.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASplepRELEELRDKNESLTMRLHE 294
Cdd:COG4717     82 EAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALE----AELAELPERLEELEERLEE 157
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  295 TlkqcQDLKTEKSQMDRKISQLleengdlsfklrefashLQQLQDALNELTEEHSRATQEWLEKQAQLEKELSTALQDKK 374
Cdd:COG4717    158 L----RELEEELEELEAELAEL-----------------QEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELE 216
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  375 CLEEKNEILQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLetlkqeAATLAANNTQLQARVETLETEQGQQEAKLLAER 454
Cdd:COG4717    217 EAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAA------LLALLGLGGSLLSLILTIAGVLFLVLGLLALLF 290
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  455 DHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLnATIQQQDQELADLKQQAKEEQAQ 534
Cdd:COG4717    291 LLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRI-EELQELLREAEELEEELQLEELE 369
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  535 LAQTLQQQEQASQGLrhqvEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKA 614
Cdd:COG4717    370 QEIAALLAEAGVEDE----EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELE 445
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  615 AKLEILQQQLQvanetRDSAQTSVTQAQREKAELSQKVEELRARVETACREqheaqAQVAELEFQLQSEQQKATEKERVA 694
Cdd:COG4717    446 EELEELREELA-----ELEAELEQLEEDGELAELLQELEELKAELRELAEE-----WAALKLALELLEEAREEYREERLP 515
                          490
                   ....*....|...
gi 1622865008  695 QEKDQLQEQLQAL 707
Cdd:COG4717    516 PVLERASEYFSRL 528
mukB PRK04863
chromosome partition protein MukB;
578-1427 3.64e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 55.73  E-value: 3.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  578 RRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLE---ILQQQLQVANETRDSAQTSVTQAQREKaELSQKVEE 654
Cdd:PRK04863   281 RRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEaesDLEQDYQAASDHLNLVQTALRQQEKIE-RYQADLEE 359
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  655 LRARVETACREQHEAQAQVAELEfqlqseqqkaTEKERVAQEKDQLQEQLQALKESLKV--TKGSleeEKRRAADALEEQ 732
Cdd:PRK04863   360 LEERLEEQNEVVEEADEQQEENE----------ARAEAAEEEVDELKSQLADYQQALDVqqTRAI---QYQQAVQALERA 426
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  733 QRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQAETEALrqELAEAIAAQrTAESECEQLVKEVAa 812
Cdd:PRK04863   427 KQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAY--QLVRKIAGE-VSRSEAWDVARELL- 502
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  813 wrERYEESQQEEAQYGAMfqeqlmtlkeecekaRQELQEAKekvagieshselQISRQQNELVELHANLARALQQVQEKE 892
Cdd:PRK04863   503 --RRLREQRHLAEQLQQL---------------RMRLSELE------------QRLRQQQRAERLLAEFCKRLGKNLDDE 553
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  893 VRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKeparagdREPEW---------LEEQQGRQFCST 963
Cdd:PRK04863   554 DELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAA-------RAPAWlaaqdalarLREQSGEEFEDS 626
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  964 QAALQAM------EREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERG-----RAQADLALEKAAkaELEM 1032
Cdd:PRK04863   627 QDVTEYMqqllerERELTVERDELAARKQALDEEIERLSQPGGSEDPRLNALAERFGgvllsEIYDDVSLEDAP--YFSA 704
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1033 RLQNA--------LNEQRVEFATLQ-----------------------EALAHALTEKEGKDQ------ELVKLRGlEAA 1075
Cdd:PRK04863   705 LYGPArhaivvpdLSDAAEQLAGLEdcpedlyliegdpdsfddsvfsvEELEKAVVVKIADRQwrysrfPEVPLFG-RAA 783
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1076 QIKELEELRQTMKQLKEQLAKKEKEHAsgsgaqseaagrteptgpKLEALRAEVSKLEQQCQQQQEQADSlERSLEAERA 1155
Cdd:PRK04863   784 REKRIEQLRAEREELAERYATLSFDVQ------------------KLQRLHQAFSRFIGSHLAVAFEADP-EAELRQLNR 844
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1156 SRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRT-KVQDHSKAEDEWKAQVARGrQEAER----KNSLISSL 1230
Cdd:PRK04863   845 RRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLNLlADETLADRVEEIREQLDEA-EEAKRfvqqHGNALAQL 923
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1231 EEEVSILNrqvlEKEGESKELKRLVMAESEKSQKLEDRLRLLqaetASNSARAAERSSAlrEEVQSLREEAEkqrvASEN 1310
Cdd:PRK04863   924 EPIVSVLQ----SDPEQFEQLKQDYQQAQQTQRDAKQQAFAL----TEVVQRRAHFSYE--DAAEMLAKNSD----LNEK 989
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1311 LRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPA-KHLCQQLQAEQAAAEKRHREELEQSK 1389
Cdd:PRK04863   990 LRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQElQDLGVPADSGAEERARARRDELHARL 1069
                          890       900       910
                   ....*....|....*....|....*....|....*....
gi 1622865008 1390 QAAGGLRAELLRAQ-RELGELIPLRQKVAEQERTAQQLR 1427
Cdd:PRK04863  1070 SANRSRRNQLEKQLtFCEAEMDNLTKKLRKLERDYHEMR 1108
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
1074-1684 3.93e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 55.75  E-value: 3.93e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1074 AAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQS--EAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSlE 1151
Cdd:TIGR00618  222 QVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKkqQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHI-K 300
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1152 AERASRAERDSALETLQGQLEEKARELGHSQSALASvqrelaalRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLE 1231
Cdd:TIGR00618  301 AVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQ--------QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISC 372
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1232 EEVSILNRqvlekegeSKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERS------SALREEVQSLREEAEKQR 1305
Cdd:TIGR00618  373 QQHTLTQH--------IHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRdlqgqlAHAKKQQELQQRYAELCA 444
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1306 VASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALV------------SELLPAKHLCQQLQ-- 1371
Cdd:TIGR00618  445 AAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLlelqeepcplcgSCIHPNPARQDIDNpg 524
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1372 ------AEQAAAEKRHREELEQSKQAAGGLRAELLR----AQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLK 1441
Cdd:TIGR00618  525 pltrrmQRGEQTYAQLETSEEDVYHQLTSERKQRASlkeqMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLS 604
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1442 KAHGLLAEENRGLGERAN--LGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKyegakvKV 1519
Cdd:TIGR00618  605 EAEDMLACEQHALLRKLQpeQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLA------SR 678
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1520 LEERQRFQEEKQKLTAQVEQLEVFQ---REQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQ----AR 1592
Cdd:TIGR00618  679 QLALQKMQSEKEQLTYWKEMLAQCQtllRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQArtvlKA 758
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1593 LNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLQSLE-----HLQKENKELRAEAERLGHELQQAGLKTK 1667
Cdd:TIGR00618  759 RTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEaeigqEIPSDEDILNLQCETLVQEEEQFLSRLE 838
                          650
                   ....*....|....*..
gi 1622865008 1668 EAEQTCRHLTAQVRSLE 1684
Cdd:TIGR00618  839 EKSATLGEITHQLLKYE 855
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
447-840 3.96e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 55.73  E-value: 3.96e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  447 EAKLLAERDHFEEEKQQLSS--LIANLQSSISNLSQAKEELEQASQA---------HGARLTAQVASLTSELTTLNATIQ 515
Cdd:COG3096    285 ERALELRRELFGARRQLAEEqyRLVEMARELEELSARESDLEQDYQAasdhlnlvqTALRQQEKIERYQEDLEELTERLE 364
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  516 QQDQELAdlkqQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKqkEQQLKEVAEKQEVTRRDHAQQLATAAEEREAS 595
Cdd:COG3096    365 EQEEVVE----EAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALD--VQQTRAIQYQQAVQALEKARALCGLPDLTPEN 438
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  596 LRERdaaLQQLEALEKEKAAKLEILQQQLQVANE-------------------TRDSAQTSVTQAQREKAE---LSQKVE 653
Cdd:COG3096    439 AEDY---LAAFRAKEQQATEEVLELEQKLSVADAarrqfekayelvckiagevERSQAWQTARELLRRYRSqqaLAQRLQ 515
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  654 ELRAR---VETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQlqalkeslkvtkgsleeekrraadaLE 730
Cdd:COG3096    516 QLRAQlaeLEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEE-------------------------LE 570
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  731 EQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEaHQAETEALRQELAEAIAAQRTAESECEQLVKEV 810
Cdd:COG3096    571 EQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLRE-QSGEALADSQEVTAAMQQLLEREREATVERDEL 649
                          410       420       430
                   ....*....|....*....|....*....|
gi 1622865008  811 AAWRERYEESQQEEAQYGAMFQEQLMTLKE 840
Cdd:COG3096    650 AARKQALESQIERLSQPGGAEDPRLLALAE 679
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1122-1612 5.04e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.77  E-value: 5.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1122 LEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELghsqsalASVQRELAALRTKVQD 1201
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL-------EELEAELEELREELEK 120
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1202 HSKAEDEWKAqvargRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSA 1281
Cdd:COG4717    121 LEKLLQLLPL-----YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ 195
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1282 RAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQA-LSTLQLEHTSTQALVSEL 1360
Cdd:COG4717    196 DLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTI 275
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1361 LPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAellraqrelgeliplrQKVAEQERTAQQLRAEKASYAEQLSML 1440
Cdd:COG4717    276 AGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPA----------------LEELEEEELEELLAALGLPPDLSPEEL 339
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1441 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVL 1520
Cdd:COG4717    340 LELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELE 419
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1521 EERQRFQEEkqKLTAQVEQLEVFQREQTKQVEELRKKLADsdqaskvQQQKLKAVqaqggESQQEAQRLQARLNELQAQL 1600
Cdd:COG4717    420 ELLEALDEE--ELEEELEELEEELEELEEELEELREELAE-------LEAELEQL-----EEDGELAELLQELEELKAEL 485
                          490
                   ....*....|..
gi 1622865008 1601 SQKEQAAEHYKL 1612
Cdd:COG4717    486 RELAEEWAALKL 497
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
220-480 5.78e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.03  E-value: 5.78e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  220 KKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQridrlallnEKQaaspLEPRELEELRDKNESLTMRLHETLKQC 299
Cdd:TIGR04523  383 KQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQ---------EKE----LLEKEIERLKETIIKNNSEIKDLTNQD 449
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  300 QDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHS---RATQEWLEKQAQLEKELSTALQDKKCL 376
Cdd:TIGR04523  450 SVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKklnEEKKELEEKVKDLTKKISSLKEKIEKL 529
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  377 E-EKNEILQgKLSQLEEHLALLRENPPQE--KGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQ---------- 443
Cdd:TIGR04523  530 EsEKKEKES-KISDLEDELNKDDFELKKEnlEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKkdlikeieek 608
                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1622865008  444 GQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQ 480
Cdd:TIGR04523  609 EKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQ 645
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
640-1177 5.82e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.07  E-value: 5.82e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  640 QAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLE 719
Cdd:PRK03918   197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE 276
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  720 --EEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLgEAHQAETEALRQElaeaiaaqr 797
Cdd:PRK03918   277 elEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL-EEKEERLEELKKK--------- 346
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  798 taESECEQLVKEVAAWRERYEESQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELVEL 877
Cdd:PRK03918   347 --LKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKEL 424
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  878 HANLARALQQVQEKEVRAQKLADDLStlQEKMAATSKEVARLETLVRKAGEQQETASRELVKeparagdREPEWLEEQQG 957
Cdd:PRK03918   425 KKAIEELKKAKGKCPVCGRELTEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRE-------LEKVLKKESEL 495
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  958 RQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNA 1037
Cdd:PRK03918   496 IKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAEL 575
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1038 LNEQRVEFATLQEALAHALTEKEGKDQELVKLRGLEaaqiKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEP 1117
Cdd:PRK03918   576 LKELEELGFESVEELEERLKELEPFYNEYLELKDAE----KELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622865008 1118 TGP------------KLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLqgQLEEKARE 1177
Cdd:PRK03918   652 LEKkyseeeyeelreEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKEL--EKLEKALE 721
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1080-1655 6.84e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.66  E-value: 6.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1080 LEELRQTMKQLKEQLAKKEKE--HASGSGAQSEAAgrteptgpkleALRAEVSKLEQQCQQQQEQADSLERSLEAERASR 1157
Cdd:PRK02224   182 LSDQRGSLDQLKAQIEEKEEKdlHERLNGLESELA-----------ELDEEIERYEEQREQARETRDEADEVLEEHEERR 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1158 AErdsaLETLQGQLEEkarelghSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSIL 1237
Cdd:PRK02224   251 EE----LETLEAEIED-------LRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREEL 319
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1238 NRQvlekegeskelkrlvmaESEKSQKLEDRlRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTS 1317
Cdd:PRK02224   320 EDR-----------------DEELRDRLEEC-RVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVED 381
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1318 QAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRA 1397
Cdd:PRK02224   382 RREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPV 461
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1398 ELLRAQRELGELiplRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVE--LDQAREK 1475
Cdd:PRK02224   462 EGSPHVETIEED---RERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRetIEEKRER 538
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1476 yVQELAAVRADAETRlAEVQREAQSTARElevmTAKYEGAKVKVLEERQRFQEEKQKLTAQVEQLEVFQREQTKQVEELR 1555
Cdd:PRK02224   539 -AEELRERAAELEAE-AEEKREAAAEAEE----EAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLR 612
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1556 KKLADSDQASKVQQQKLKAVQAQggESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQL 1635
Cdd:PRK02224   613 EKREALAELNDERRERLAEKRER--KRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL 690
                          570       580
                   ....*....|....*....|
gi 1622865008 1636 QSLEHLQKENKELRAEAERL 1655
Cdd:PRK02224   691 EELEELRERREALENRVEAL 710
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
459-706 1.19e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 1.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  459 EEKQQLSSLIANLQSSISNLSQAKEELEQASQAhgarLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEeqaqlaqt 538
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKA----LLKQLAALERRIAALARRIRALEQELAALEAELAE-------- 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  539 lqqqeqasqgLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRerdaALQQLEALEKEKAAKLE 618
Cdd:COG4942     88 ----------LEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVR----RLQYLKYLAPARREQAE 153
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  619 ILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRArvetacrEQHEAQAQVAELEFQLQSEQQKATEKERVAQEKD 698
Cdd:COG4942    154 ELRADLAELAALRAELEAERAELEALLAELEEERAALEA-------LKAERQKLLARLEKELAELAAELAELQQEAEELE 226

                   ....*...
gi 1622865008  699 QLQEQLQA 706
Cdd:COG4942    227 ALIARLEA 234
mukB PRK04863
chromosome partition protein MukB;
1276-1687 1.22e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 54.19  E-value: 1.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1276 TASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFfQKEQALSTLQLEHTSTQA 1355
Cdd:PRK04863   277 HANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKIERYQA 355
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1356 LVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELiplrQKVAEQERTAQQL--RAEKASY 1433
Cdd:PRK04863   356 DLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQ----QTRAIQYQQAVQAleRAKQLCG 431
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1434 AEQLSmLKKAHGLLAE---ENRGLGERANLGRQFLEVElDQAREKYVQELAAVRADAetrlAEVQR-EAQSTARELEvmt 1509
Cdd:PRK04863   432 LPDLT-ADNAEDWLEEfqaKEQEATEELLSLEQKLSVA-QAAHSQFEQAYQLVRKIA----GEVSRsEAWDVARELL--- 502
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1510 akyegakvkvleerqRFQEEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAVQaqggESQQEAQRL 1589
Cdd:PRK04863   503 ---------------RRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDED----ELEQLQEEL 563
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1590 QARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQAGLKTKEA 1669
Cdd:PRK04863   564 EARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLEREREL 643
                          410
                   ....*....|....*...
gi 1622865008 1670 EQTCRHLTAQVRSLEAQV 1687
Cdd:PRK04863   644 TVERDELAARKQALDEEI 661
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
596-749 1.30e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 51.85  E-value: 1.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  596 LRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVE------TACREQHEA 669
Cdd:COG1579     12 LQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKkyeeqlGNVRNNKEY 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  670 QAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:COG1579     92 EALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
530-937 1.75e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.23  E-value: 1.75e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  530 EEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVaeKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEAL 609
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEEL--REELEKLEKLLQLLPLYQELEALEAELAELPERLEEL 151
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  610 E------KEKAAKLEILQQQLQVANETRDSAQTSVTQAQREK-AELSQKVEELRARVETACREQHEAQAQVAELEFQLQS 682
Cdd:COG4717    152 EerleelRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  683 EQQKAtekeRVAQEKDQLQEQLQALK-----ESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKEL 757
Cdd:COG4717    232 LENEL----EAAALEERLKEARLLLLiaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL 307
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  758 EEEKAGRKGLEARLQQLGEAHQAETEALRQELAEAIAAQRTAesecEQLVKEVAAWRERYEESQQEEAQYgAMFQEQLMT 837
Cdd:COG4717    308 QALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEEL----QELLREAEELEEELQLEELEQEIA-ALLAEAGVE 382
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  838 LKEECEKARQELQEAKEKVAGIESHSElQISRQQNELVEL--HANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKE 915
Cdd:COG4717    383 DEEELRAALEQAEEYQELKEELEELEE-QLEELLGELEELleALDEEELEEELEELEEELEELEEELEELREELAELEAE 461
                          410       420
                   ....*....|....*....|....
gi 1622865008  916 VARLET--LVRKAGEQQETASREL 937
Cdd:COG4717    462 LEQLEEdgELAELLQELEELKAEL 485
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
644-988 1.93e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.42  E-value: 1.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  644 EKAELSQKVEELRARVETACREQHEAQAQVAEL--EFQLQSEQQKATEKERVAQEkDQLQEQLQALKESLKVtkGSLEEE 721
Cdd:COG3096    279 ERRELSERALELRRELFGARRQLAEEQYRLVEMarELEELSARESDLEQDYQAAS-DHLNLVQTALRQQEKI--ERYQED 355
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  722 KRRAADALEEQQrcisELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQAETEALRQelaeAIAAQRTAES 801
Cdd:COG3096    356 LEELTERLEEQE----EVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQ----AVQALEKARA 427
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  802 ECEQLVKEVAAWRERYEESQ-QEEAQYGAMFQ-EQLMTLKEECEKARQELQEAKEKVAG--------------IESHSEL 865
Cdd:COG3096    428 LCGLPDLTPENAEDYLAAFRaKEQQATEEVLElEQKLSVADAARRQFEKAYELVCKIAGeversqawqtarelLRRYRSQ 507
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  866 Q--------ISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASREL 937
Cdd:COG3096    508 QalaqrlqqLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQL 587
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622865008  938 VKEPARA---GDREPEW---------LEEQQGRQFCSTQAALQAM------EREAEQMGNELERLRAAL 988
Cdd:COG3096    588 EQLRARIkelAARAPAWlaaqdalerLREQSGEALADSQEVTAAMqqllerEREATVERDELAARKQAL 656
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
217-739 2.05e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.10  E-value: 2.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  217 RRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLallNEKQAASPLEPRELEELRDKNESLTMRLHETL 296
Cdd:TIGR04523  148 KKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKI---KNKLLKLELLLSNLKKKIQKNKSLESQISELK 224
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  297 KQCQDLKTEKSQMDRKISQLLEEngdlsfklrefashLQQLQDALNELTEEHSRATQEWLEKQAQLEkelstalQDKKCL 376
Cdd:TIGR04523  225 KQNNQLKDNIEKKQQEINEKTTE--------------ISNTQTQLNQLKDEQNKIKKQLSEKQKELE-------QNNKKI 283
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  377 EEKNEILQGKLSQLEEhlaLLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEtleteqgQQEAKLLAERDH 456
Cdd:TIGR04523  284 KELEKQLNQLKSEISD---LNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLN-------EQISQLKKELTN 353
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  457 FEEEKQQLSSLIANLQSSISNLSQAKEELEQASQahgarltaqvaSLTSELTTLNATIQQQDQELADLKQQAKeeqaqla 536
Cdd:TIGR04523  354 SESENSEKQRELEEKQNEIEKLKKENQSYKQEIK-----------NLESQINDLESKIQNQEKLNQQKDEQIK------- 415
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  537 qtlqqqeqasqglrhqVEQLSSSLKQKEQQ-LKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKE--- 612
Cdd:TIGR04523  416 ----------------KLQQEKELLEKEIErLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSink 479
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  613 KAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATeKER 692
Cdd:TIGR04523  480 IKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELK-KEN 558
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1622865008  693 VAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISEL 739
Cdd:TIGR04523  559 LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEI 605
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
866-1102 2.27e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  866 QISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKeparag 945
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE------ 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  946 drepewLEEQQGRQfcstQAALQAMEREAEQMGneleRLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKA 1025
Cdd:COG4942     95 ------LRAELEAQ----KEELAELLRALYRLG----RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA 160
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622865008 1026 AKAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHA 1102
Cdd:COG4942    161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
409-659 2.46e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 52.71  E-value: 2.46e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  409 LGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERdhfeeEKQQLSSLIANLQSSISNLSQAKEELEQA 488
Cdd:COG3206    157 LAEAYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEA 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  489 sQAHGARLTAQVASLTSELTTLNATIQQ--QDQELADLKQQAKEeqaqlaqtlqqqeqasqgLRHQVEQLSSSLKQKEQQ 566
Cdd:COG3206    232 -RAELAEAEARLAALRAQLGSGPDALPEllQSPVIQQLRAQLAE------------------LEAELAELSARYTPNHPD 292
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  567 LKEVAEKQEVTRRDHAQQLATAAEEREA---SLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQ--A 641
Cdd:COG3206    293 VIALRAQIAALRAQLQQEAQRILASLEAeleALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESllQ 372
                          250
                   ....*....|....*...
gi 1622865008  642 QREKAELSQKVEELRARV 659
Cdd:COG3206    373 RLEEARLAEALTVGNVRV 390
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
414-931 4.17e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.94  E-value: 4.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  414 QLETLKQEAATLAANNTQLQARVETLETEQgqqeakllaerDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHg 493
Cdd:TIGR04523  146 EIKKKEKELEKLNNKYNDLKKQKEELENEL-----------NLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKN- 213
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  494 ARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRH---QVEQLSSSLKQKEQQLKEV 570
Cdd:TIGR04523  214 KSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEkqkELEQNNKKIKELEKQLNQL 293
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  571 AEKQEVTRRDHAQQLATAAEEReasLRERDAALQQLEalekekaAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQ 650
Cdd:TIGR04523  294 KSEISDLNNQKEQDWNKELKSE---LKNQEKKLEEIQ-------NQISQNNKIISQLNEQISQLKKELTNSESENSEKQR 363
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  651 KVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALE 730
Cdd:TIGR04523  364 ELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIK 443
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  731 EQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLgeahQAETEALRQELAEAIAAQRTAESECEQLVKEV 810
Cdd:TIGR04523  444 DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQK----QKELKSKEKELKKLNEEKKELEEKVKDLTKKI 519
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  811 AAWRERYEESQQEEAQygamFQEQLMTLKEECEKARQELQeakekvagiESHSELQISRQQNELVELHANLARALQQVQE 890
Cdd:TIGR04523  520 SSLKEKIEKLESEKKE----KESKISDLEDELNKDDFELK---------KENLEKEIDEKNKEIEELKQTQKSLKKKQEE 586
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 1622865008  891 KEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQE 931
Cdd:TIGR04523  587 KQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENE 627
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
215-572 4.40e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.99  E-value: 4.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKD-----AQIAMMQQRIDRLAL----LNEKQAASPLEPRELEELRDKN 285
Cdd:PRK03918   373 ELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEiskitARIGELKKEIKELKKaieeLKKAKGKCPVCGRELTEEHRKE 452
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  286 --ESLTMRLHETLKQCQDLKTEKSQMD---RKISQLLEENGDLSfKLREFASHLQQLQDALNELT-EEHSRATQEW---L 356
Cdd:PRK03918   453 llEEYTAELKRIEKELKEIEEKERKLRkelRELEKVLKKESELI-KLKELAEQLKELEEKLKKYNlEELEKKAEEYeklK 531
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  357 EKQAQLEKELSTALQD---KKCLEEKNEILQGKLSQLEEHLA----LLRENPPQEKGEVLGDVLQLETLKQEAATLAANN 429
Cdd:PRK03918   532 EKLIKLKGEIKSLKKElekLEELKKKLAELEKKLDELEEELAellkELEELGFESVEELEERLKELEPFYNEYLELKDAE 611
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  430 TQLQA---RVETLETEQGQQEAKLLAERDHFEEEKQQLSSLianlqssisNLSQAKEELEQASQAHgARLTAQVASLTSE 506
Cdd:PRK03918   612 KELEReekELKKLEEELDKAFEELAETEKRLEELRKELEEL---------EKKYSEEEYEELREEY-LELSRELAGLRAE 681
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622865008  507 LTTLNATIQQQDQELADLKQQAKE--EQAQLAQTLQQQEQASQGLRHQVEQLSSSLkqKEQQLKEVAE 572
Cdd:PRK03918   682 LEELEKRREEIKKTLEKLKEELEEreKAKKELEKLEKALERVEELREKVKKYKALL--KERALSKVGE 747
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
497-745 5.28e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 5.28e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  497 TAQVASLTSELTTLNATIQQQDQELADLKQQAKEeqaqlaqtlqqQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEV 576
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKA-----------LLKQLAALERRIAALARRIRALEQELAALEAELAE 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  577 TRRDhAQQLATAAEEREASLRERDAALQQLEALEKEKAakleILQQQLQVANETRDSAQTSVTQAQREKAElsqkveELR 656
Cdd:COG4942     88 LEKE-IAELRAELEAQKEELAELLRALYRLGRQPPLAL----LLSPEDFLDAVRRLQYLKYLAPARREQAE------ELR 156
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  657 ARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCI 736
Cdd:COG4942    157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236

                   ....*....
gi 1622865008  737 SELKAETRS 745
Cdd:COG4942    237 AAAAERTPA 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
687-936 6.23e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 6.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  687 ATEKERVAQEKDQLQEQLQALKESLKvtkgSLEEEKRRAADALEEQQRCISELKAETRSLVEQhkqeqkeLEEEKAGRKG 766
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELA----ALKKEEKALLKQLAALERRIAALARRIRALEQE-------LAALEAELAE 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  767 LEARLQQLgeahQAETEALRQELAEAI-AAQRTAESECEQLVkevaawreryeeSQQEEAQYGAMFQEQLMTLKEECEKA 845
Cdd:COG4942     88 LEKEIAEL----RAELEAQKEELAELLrALYRLGRQPPLALL------------LSPEDFLDAVRRLQYLKYLAPARREQ 151
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  846 RQELQEAKEKVAGIESHSELQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRK 925
Cdd:COG4942    152 AEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
                          250
                   ....*....|.
gi 1622865008  926 AGEQQETASRE 936
Cdd:COG4942    232 LEAEAAAAAER 242
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
263-881 6.23e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.59  E-value: 6.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  263 LLNEKQAASPLEPRELEELRDKNESLTMRLHetlKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREfashLQQLQDALN 342
Cdd:TIGR00606  413 LCADLQSKERLKQEQADEIRDEKKGLGRTIE---LKKEILEKKQEELKFVIKELQQLEGSSDRILEL----DQELRKAER 485
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  343 ELTEEHSRATQEWLEKQAQ-LEKELSTALQDKKCLEEKNEILQGKLSQLEEHLAL----------LRENPPQEKGEV--- 408
Cdd:TIGR00606  486 ELSKAEKNSLTETLKKEVKsLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLtkdkmdkdeqIRKIKSRHSDELtsl 565
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  409 LGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANL------QSSISNLSQAK 482
Cdd:TIGR00606  566 LGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLK 645
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  483 EELEQASQ--AHGARLTAQVASLTSELTTLN--------------ATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQAS 546
Cdd:TIGR00606  646 EEIEKSSKqrAMLAGATAVYSQFITQLTDENqsccpvcqrvfqteAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRR 725
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  547 QGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDhAQQLATAAEEREASLRERDAALQQLEALEKEkAAKLEILQQQL-- 624
Cdd:TIGR00606  726 DEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD-IQRLKNDIEEQETLLGTIMPEEESAKVCLTD-VTIMERFQMELkd 803
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  625 -------QVANETRDSAQTSVTQAQREKAE-------LSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEK 690
Cdd:TIGR00606  804 verkiaqQAAKLQGSDLDRTVQQVNQEKQEkqheldtVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR 883
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  691 ERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEAR 770
Cdd:TIGR00606  884 QQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENK 963
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  771 LQQLGEAHQAETEalrQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEaqygAMFQEQLMTLKEEcekarQELQ 850
Cdd:TIGR00606  964 IQDGKDDYLKQKE---TELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQE----RWLQDNLTLRKRE-----NELK 1031
                          650       660       670
                   ....*....|....*....|....*....|..
gi 1622865008  851 EAKEKVAGIESH-SELQISRQQNELVELHANL 881
Cdd:TIGR00606 1032 EVEEELKQHLKEmGQMQVLQMKQEHQKLEENI 1063
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
633-860 6.56e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 6.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  633 SAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKErvaQEKDQLQEQLQALKESLK 712
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  713 VTKGSLEEEKRRAADALEEQQRciSELKAETRSLVEQHKQEQKELEEekagrkgleARLQQLGEAHQAETEALR---QEL 789
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYR--LGRQPPLALLLSPEDFLDAVRRL---------QYLKYLAPARREQAEELRadlAEL 162
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622865008  790 AEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIE 860
Cdd:COG4942    163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
1248-1659 7.12e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.49  E-value: 7.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1248 SKELKRLVMAESEKSQKLE---DRLRLLQaetasNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEE 1324
Cdd:COG3096    312 ARELEELSARESDLEQDYQaasDHLNLVQ-----TALRQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEA 386
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1325 LGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAellraqr 1404
Cdd:COG3096    387 AEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLE------- 459
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1405 elgelipLRQKVAEQERTAQQlraekasYAEQLSMLKKAHGLLAEENRGLGERANLgRQFLEVELDQARekyVQELAAVR 1484
Cdd:COG3096    460 -------LEQKLSVADAARRQ-------FEKAYELVCKIAGEVERSQAWQTARELL-RRYRSQQALAQR---LQQLRAQL 521
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1485 ADAETRLAEvQREAQSTARELEvmtakyegakvkvleerqrfQEEKQKLTAQvEQLEVFQREQTKQVEELRKKLADSDQA 1564
Cdd:COG3096    522 AELEQRLRQ-QQNAERLLEEFC--------------------QRIGQQLDAA-EELEELLAELEAQLEELEEQAAEAVEQ 579
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1565 SKVQQQKLKAVQAQGGESQQEAQR---LQARLNELQAQL------SQKEQAAEHYKLQMEKAKTHydAKKQQNQELQEQL 1635
Cdd:COG3096    580 RSELRQQLEQLRARIKELAARAPAwlaAQDALERLREQSgealadSQEVTAAMQQLLEREREATV--ERDELAARKQALE 657
                          410       420
                   ....*....|....*....|....*...
gi 1622865008 1636 QSLEHLQK----ENKELRAEAERLGHEL 1659
Cdd:COG3096    658 SQIERLSQpggaEDPRLLALAERLGGVL 685
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1078-1308 7.41e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 7.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1078 KELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASR 1157
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1158 AERDSALETLQGQleEKARELGHSQSALASVqRELAALRTKVQDHskaedewKAQVARGRQEAERKNSLISSLEEEVSIL 1237
Cdd:COG4942    107 AELLRALYRLGRQ--PPLALLLSPEDFLDAV-RRLQYLKYLAPAR-------REQAEELRADLAELAALRAELEAERAEL 176
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622865008 1238 NRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAErssaLREEVQSLREEAEKQRVAS 1308
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE----LEALIARLEAEAAAAAERT 243
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
1044-1671 7.53e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.51  E-value: 7.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1044 EFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPT-GPKL 1122
Cdd:pfam02463  167 LKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLlQELL 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1123 EALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDH 1202
Cdd:pfam02463  247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKA 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1203 SKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSAR 1282
Cdd:pfam02463  327 EKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKE 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1283 AAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLP 1362
Cdd:pfam02463  407 AQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1363 AKHLCQQLQAEQAAAEKRHREELE----QSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLS 1438
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKvllaLIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKL 566
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1439 MLKKAHGLLAEENRG--LGERANLGRQFLEVELDQAREKYVQELAAVRAD-AETRLAEVQREAQSTARELEVMTAKYEGA 1515
Cdd:pfam02463  567 VRALTELPLGARKLRllIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADeDDKRAKVVEGILKDTELTKLKESAKAKES 646
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1516 KVKVLEERQRFQEEKQKLTAQVEQLevfQREQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNE 1595
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSEL---TKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622865008 1596 LQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQAGLKTKEAEQ 1671
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQ 799
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
832-1042 8.09e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 8.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  832 QEQLMTLKEECEKARQELQEAKEKVAGIEShselQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAA 911
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLK----QLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  912 TSKEVARLETLVRKAGEQQETASRELVKEPARAgDREPEWLE------EQQGRQFCSTQAALQAMEREAEQMGNELERLR 985
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDA-VRRLQYLKylaparREQAEELRADLAELAALRAELEAERAELEALL 180
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622865008  986 AALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALNEQR 1042
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
213-520 8.26e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 8.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  213 QFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLAllnekqaasplepRELEELRDKNESLTMRL 292
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-------------EALDELRAELTLLNEEA 819
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  293 HETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHsratQEWLEKQAQLEKELSTALQD 372
Cdd:TIGR02168  820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL----EALLNERASLEEALALLRSE 895
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  373 KKCLEEKNEILQGKLSQLEEHLALLREnppqEKGEVlgdVLQLETLKQEAATLAAnntQLQARVETLETEQGQQEAKLLA 452
Cdd:TIGR02168  896 LEELSEELRELESKRSELRRELEELRE----KLAQL---ELRLEGLEVRIDNLQE---RLSEEYSLTLEEAEALENKIED 965
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622865008  453 ERDHFEEEKQQLSSLIANLQSsiSNLSqAKEELEQASQAHGaRLTAQVASLTSELTTLNATIQQQDQE 520
Cdd:TIGR02168  966 DEEEARRRLKRLENKIKELGP--VNLA-AIEEYEELKERYD-FLTAQKEDLTEAKETLEEAIEEIDRE 1029
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1236-1688 8.35e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 8.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1236 ILNRQVLEKEGESKELKrlvmAESEKSQKLEDRLRLLQAETAsnsaRAAERSSALREEVQSLREEAEKQRVASE--NLRQ 1313
Cdd:COG4717     68 LNLKELKELEEELKEAE----EKEEEYAELQEELEELEEELE----ELEAELEELREELEKLEKLLQLLPLYQEleALEA 139
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1314 ELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHlcqQLQAEQAAAEKRHREELEQSKQAAG 1393
Cdd:COG4717    140 ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEELQQRLAELEEELE 216
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1394 GLRAELLRAQRELGELIPLRQKVAEQERTaQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAR 1473
Cdd:COG4717    217 EAQEELEELEEELEQLENELEAAALEERL-KEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAR 295
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1474 EKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQrfqEEKQKLTAQVEQLEvfQREQTKQVEE 1553
Cdd:COG4717    296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRI---EELQELLREAEELE--EELQLEELEQ 370
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1554 LRKKLADSDQASKVQQQKLKAVQAQggesqqEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAkthydakkQQNQELQE 1633
Cdd:COG4717    371 EIAALLAEAGVEDEEELRAALEQAE------EYQELKEELEELEEQLEELLGELEELLEALDEE--------ELEEELEE 436
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622865008 1634 QLQSLEHLQKENKELRAEAERLGHELQQAGLKTK--EAEQTCRHLTAQVRSLEAQVA 1688
Cdd:COG4717    437 LEEELEELEEELEELREELAELEAELEQLEEDGElaELLQELEELKAELRELAEEWA 493
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
464-734 9.51e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 51.21  E-value: 9.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  464 LSSLIAN--LQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATiqQQDQELADLKQQAKEEqaqlaqtlqq 541
Cdd:PRK10929     9 MAWLLSWgaYAATAPDEKQITQELEQAKAAKTPAQAEIVEALQSALNWLEER--KGSLERAKQYQQVIDN---------- 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  542 QEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTR-RDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEIL 620
Cdd:PRK10929    77 FPKLSAELRQQLNNERDEPRSVPPNMSTDALEQEILQvSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEI 156
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  621 QQQLQVA-NETRDSAQTSVTQAQREKAELSQKVEEL--------------RARVETACREQHEAQAQVAELEFQLQSEQQ 685
Cdd:PRK10929   157 ERRLQTLgTPNTPLAQAQLTALQAESAALKALVDELelaqlsannrqelaRLRSELAKKRSQQLDAYLQALRNQLNSQRQ 236
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622865008  686 KATEK--ERVAQEKDQLQEQLQALKESLKVTK---GSLEEEKRRaADALEEQQR 734
Cdd:PRK10929   237 REAERalESTELLAEQSGDLPKSIVAQFKINRelsQALNQQAQR-MDLIASQQR 289
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
777-1132 1.18e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 50.82  E-value: 1.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  777 AHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYgamfQEQLMTLKEECEKARQELQEAKEKV 856
Cdd:PRK10929    20 ATAPDEKQITQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQY----QQVIDNFPKLSAELRQQLNNERDEP 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  857 AGIESHS-----ELQISRQQNELVElhanLARALQQVQEkevRAQKLADDLSTLQekmaatskevarletlvrkagEQQE 931
Cdd:PRK10929    96 RSVPPNMstdalEQEILQVSSQLLE----KSRQAQQEQD---RAREISDSLSQLP---------------------QQQT 147
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  932 TASRELVKEPARAGDR-EPEWLEEQQgrQFCSTQA---ALQAM--EREAEQMG----NELERLRAALMESQGQQQEERGQ 1001
Cdd:PRK10929   148 EARRQLNEIERRLQTLgTPNTPLAQA--QLTALQAesaALKALvdELELAQLSannrQELARLRSELAKKRSQQLDAYLQ 225
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1002 QEREvaRLTQERGRaQADLALEKAAK-AELEMRLQNALNEQrveFATLQEaLAHALTEkEGKDQELVKLRGLEAAqiKEL 1080
Cdd:PRK10929   226 ALRN--QLNSQRQR-EAERALESTELlAEQSGDLPKSIVAQ---FKINRE-LSQALNQ-QAQRMDLIASQQRQAA--SQT 295
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622865008 1081 EELRQTMKQLKEQlakkekehasgsgAQ----SEAAGrteptgpklEALRAEVSKL 1132
Cdd:PRK10929   296 LQVRQALNTLREQ-------------SQwlgvSNALG---------EALRAQVARL 329
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
1206-1721 1.19e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.49  E-value: 1.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1206 EDEWKAQVARGRQEAERKNSlissleEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAE 1285
Cdd:pfam05483  103 QKENKLQENRKIIEAQRKAI------QELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEY 176
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1286 RSSALREEVQSLREEAEKQ-------RVASENLRQELTSQAERAEELGQEL-KAWQEKFFQKEQALSTLQLEHTSTQALV 1357
Cdd:pfam05483  177 EREETRQVYMDLNNNIEKMilafeelRVQAENARLEMHFKLKEDHEKIQHLeEEYKKEINDKEKQVSLLLIQITEKENKM 256
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1358 SELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAEL----LRAQRELGELIPLRQKVAEQERTAQQLRAEKASY 1433
Cdd:pfam05483  257 KDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELedikMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQ 336
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1434 AEQLSMLKKAHGLLaeenrglgeranlgrqfleveldqarekyVQELAAVRADAETRLAEVQREAQSTARELEVMTAkye 1513
Cdd:pfam05483  337 MEELNKAKAAHSFV-----------------------------VTEFEATTCSLEELLRTEQQRLEKNEDQLKIITM--- 384
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1514 gakvkvleerqrfqeEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAR- 1592
Cdd:pfam05483  385 ---------------ELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQARe 449
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1593 --LNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLqslEHLQKENKELRAEAERLGHELQQAGLKTKEAE 1670
Cdd:pfam05483  450 keIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHC---DKLLLENKELTQEASDMTLELKKHQEDIINCK 526
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622865008 1671 QTCRHLTAQVRSLEAQvahaDQQLRDlgKFQVATDALKSREPQAKPQLDLS 1721
Cdd:pfam05483  527 KQEERMLKQIENLEEK----EMNLRD--ELESVREEFIQKGDEVKCKLDKS 571
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
592-1030 1.27e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 1.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  592 REASLRERDAALQQLEALEkEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVE--ELRARVETACREQHEA 669
Cdd:COG4717     66 PELNLKELKELEEELKEAE-EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAEL 144
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  670 QAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTK----GSLEEEKRRAADALEEQQRCISELKAETRS 745
Cdd:COG4717    145 PERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATeeelQDLAEELEELQQRLAELEEELEEAQEELEE 224
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  746 LVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEA 825
Cdd:COG4717    225 LEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  826 qygamfqEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELVELHANLARALQqvQEKEVRAQKLADDLSTL 905
Cdd:COG4717    305 -------EELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEE--LEEELQLEELEQEIAAL 375
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  906 QEKMAATSKEvaRLETLVRKAGEQQETASRELVKEpARAGDREPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLR 985
Cdd:COG4717    376 LAEAGVEDEE--ELRAALEQAEEYQELKEELEELE-EQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELR 452
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1622865008  986 AALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAEL 1030
Cdd:COG4717    453 EELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKL 497
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
326-707 1.35e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.72  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  326 KLREFASHLQQLQDALNELTEEHSR--ATQEWLEKQAQLEKELSTALQDKkcleekneilqgklsqlEEHLALLRENPPQ 403
Cdd:COG3096    283 LSERALELRRELFGARRQLAEEQYRlvEMARELEELSARESDLEQDYQAA-----------------SDHLNLVQTALRQ 345
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  404 EKgevlgdvlQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANL----------QS 473
Cdd:COG3096    346 QE--------KIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALdvqqtraiqyQQ 417
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  474 SISNLSQAK-------------EELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKE-EQAQLAQTL 539
Cdd:COG3096    418 AVQALEKARalcglpdltpenaEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEvERSQAWQTA 497
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  540 QQQEQASQGLRHQVEQLSsslkQKEQQLKEVaeKQEVTRRDHAQQLATAAEEREAslRERDAAlQQLEALEKEKAAKLEI 619
Cdd:COG3096    498 RELLRRYRSQQALAQRLQ----QLRAQLAEL--EQRLRQQQNAERLLEEFCQRIG--QQLDAA-EELEELLAELEAQLEE 568
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  620 LQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEfQLQSEQQKATEKERVA-QEKD 698
Cdd:COG3096    569 LEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQ-EVTAAMQQLLEREREAtVERD 647

                   ....*....
gi 1622865008  699 QLQEQLQAL 707
Cdd:COG3096    648 ELAARKQAL 656
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
1380-1686 1.47e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.34  E-value: 1.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1380 RHREELEQSKQAAGGLRAELLRAQRELGE----LIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAhgllaeenrgLG 1455
Cdd:COG3096    275 RHANERRELSERALELRRELFGARRQLAEeqyrLVEMARELEELSARESDLEQDYQAASDHLNLVQTA----------LR 344
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1456 ERANLGRQflEVELDQAREKyVQELAAVRADAETRLAEvqREAQSTARELEVMTAKYEGAKVK-VLEERQR----FQ--- 1527
Cdd:COG3096    345 QQEKIERY--QEDLEELTER-LEEQEEVVEEAAEQLAE--AEARLEAAEEEVDSLKSQLADYQqALDVQQTraiqYQqav 419
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1528 ---EEKQKLTA-----------QVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEA------- 1586
Cdd:COG3096    420 qalEKARALCGlpdltpenaedYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSQawqtare 499
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1587 -------QRLQA-RLNELQAQLSQKEQAAEhyklQMEKAKTHYDAKKQQNQELQEQLQSLEHLQkenKELRAEAERLGHE 1658
Cdd:COG3096    500 llrryrsQQALAqRLQQLRAQLAELEQRLR----QQQNAERLLEEFCQRIGQQLDAAEELEELL---AELEAQLEELEEQ 572
                          330       340
                   ....*....|....*....|....*...
gi 1622865008 1659 LQQAGLKTKEAEQTCRHLTAQVRSLEAQ 1686
Cdd:COG3096    573 AAEAVEQRSELRQQLEQLRARIKELAAR 600
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1292-1687 1.51e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.42  E-value: 1.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1292 EEVQSLREEAEKQRvasENLRQELTSQAERAEELGQELkawqekffqkEQALSTLQLEHTSTQALvsellpakhlcQQLQ 1371
Cdd:PRK02224   261 EDLRETIAETERER---EELAEEVRDLRERLEELEEER----------DDLLAEAGLDDADAEAV-----------EARR 316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1372 AEQAAAEKRHREELEQSKQAAGGLRAEllrAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEEN 1451
Cdd:PRK02224   317 EELEDRDEELRDRLEECRVAAQAHNEE---AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEI 393
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1452 RGLGERANlgrqFLEVELDQArEKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAK-------------VK 1518
Cdd:PRK02224   394 EELRERFG----DAPVDLGNA-EDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphVE 468
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1519 VLEERQrfqEEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQ-----KLKAVQAQGGESQQE-AQRLQAR 1592
Cdd:PRK02224   469 TIEEDR---ERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERredleELIAERRETIEEKRErAEELRER 545
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1593 LNELQAQLSQKEQAAEHYKLQMEKAKTH---YDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQAGLKTKEA 1669
Cdd:PRK02224   546 AAELEAEAEEKREAAAEAEEEAEEAREEvaeLNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDER 625
                          410
                   ....*....|....*...
gi 1622865008 1670 EQTCRHLTAQVRSLEAQV 1687
Cdd:PRK02224   626 RERLAEKRERKRELEAEF 643
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
653-1198 2.19e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 2.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  653 EELRARVETAcREQHEAQAQVAELEFQLQSEQQKATEKERV-----AQEKDQLQEQLQALKESLKVTKGSLEEEKRRAAD 727
Cdd:COG4913    238 ERAHEALEDA-REQIELLEPIRELAERYAAARERLAELEYLraalrLWFAQRRLELLEAELEELRAELARLEAELERLEA 316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  728 ALEEQQRCISELKAETRSL----VEQHKQEQKELEEEKAGRKG----LEARLQQLGEAHQAETEALRQELAEAIAAQRTA 799
Cdd:COG4913    317 RLDALREELDELEAQIRGNggdrLEQLEREIERLERELEERERrrarLEALLAALGLPLPASAEEFAALRAEAAALLEAL 396
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  800 ESECEQLVKEVAAWRERYEESQQEEAQygamfqeqlmtLKEECE--KARQ-----ELQEAKEKVAgieshSELQISRQQ- 871
Cdd:COG4913    397 EEELEALEEALAEAEAALRDLRRELRE-----------LEAEIAslERRKsnipaRLLALRDALA-----EALGLDEAEl 460
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  872 ---NELVELHA--------------NLARAL-------QQVQEKeVRAQKLADDLSTLQEKMAATSKEVARLE--TLVRK 925
Cdd:COG4913    461 pfvGELIEVRPeeerwrgaiervlgGFALTLlvppehyAAALRW-VNRLHLRGRLVYERVRTGLPDPERPRLDpdSLAGK 539
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  926 ageqqetasreLVKEPARAGDrepeWLEEQQGRQF----CSTQAALQAMER---EAEQMGNELERLRAALMESQGQQQEE 998
Cdd:COG4913    540 -----------LDFKPHPFRA----WLEAELGRRFdyvcVDSPEELRRHPRaitRAGQVKGNGTRHEKDDRRRIRSRYVL 604
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  999 RGQQEREVARLTQERGRAQADLALEKAAKAELEmRLQNALNEQRVEFATLQEaLAHALTEKEGKDQELVKLRgleaAQIK 1078
Cdd:COG4913    605 GFDNRAKLAALEAELAELEEELAEAEERLEALE-AELDALQERREALQRLAE-YSWDEIDVASAEREIAELE----AELE 678
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1079 ELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRA 1158
Cdd:COG4913    679 RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAA 758
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1622865008 1159 ERDSALETLQGQLEEKARELghsQSALASVQRELAALRTK 1198
Cdd:COG4913    759 LGDAVERELRENLEERIDAL---RARLNRAEEELERAMRA 795
PRK11281 PRK11281
mechanosensitive channel MscK;
422-718 2.21e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 49.91  E-value: 2.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  422 AATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQaHGARLTAQVA 501
Cdd:PRK11281    19 LLCLSSAFARAASNGDLPTEADVQAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQ-QLAQAPAKLR 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  502 SLTSELTTLNATIQQQDQE------LADLKQQ-AKEEQAQLAQTLQQQEQASQ--GLRHQVE----QLSSSLKQKEQ--- 565
Cdd:PRK11281    98 QAQAELEALKDDNDEETREtlstlsLRQLESRlAQTLDQLQNAQNDLAEYNSQlvSLQTQPEraqaALYANSQRLQQirn 177
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  566 QLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQ---QLEALEK----EKAAKLEILQQQLQVanetrdsAQTSV 638
Cdd:PRK11281   178 LLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQRKSLEgntQLQDLLQkqrdYLTARIQRLEHQLQL-------LQEAI 250
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  639 TQAQREKAElsQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKE--------RVAQEKDQLQEQLQALKES 710
Cdd:PRK11281   251 NSKRLTLSE--KTVQEAQSQDEAARIQANPLVAQELEINLQLSQRLLKATEKLntltqqnlRVKNWLDRLTQSERNIKEQ 328

                   ....*...
gi 1622865008  711 LKVTKGSL 718
Cdd:PRK11281   329 ISVLKGSL 336
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1193-1325 2.97e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.09  E-value: 2.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1193 AALRTKVQDHSKAEDEwKAQVARGRQEAERknsliSSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLL 1272
Cdd:COG2433    380 EALEELIEKELPEEEP-EAEREKEHEEREL-----TEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEA 453
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622865008 1273 QAEtASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELtsqaERAEEL 1325
Cdd:COG2433    454 RSE-ERREIRKDREISRLDREIERLERELEEERERIEELKRKL----ERLKEL 501
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
315-983 3.06e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.57  E-value: 3.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  315 QLLEENgdlsFKLREFASHLQQLQDALNELTEEHSRATqEWLEK---QAQLEKELSTALQDKKCLEEKNEILQGKLSQLE 391
Cdd:COG3096    300 QLAEEQ----YRLVEMARELEELSARESDLEQDYQAAS-DHLNLvqtALRQQEKIERYQEDLEELTERLEEQEEVVEEAA 374
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  392 EHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQ-QEAKLLAE--RDH---FEEEKQQLS 465
Cdd:COG3096    375 EQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARALcGLPDLTPEnaEDYlaaFRAKEQQAT 454
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  466 SLIANLQSSISNLSQAKEELEQASQAhgarltaqVASLTSELTTLNA--TIQQQDQELADLKQQAKEEQAQLAQTLQQQE 543
Cdd:COG3096    455 EEVLELEQKLSVADAARRQFEKAYEL--------VCKIAGEVERSQAwqTARELLRRYRSQQALAQRLQQLRAQLAELEQ 526
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  544 QAS--QGLRHQVEQLSSSLKQK---EQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEK------E 612
Cdd:COG3096    527 RLRqqQNAERLLEEFCQRIGQQldaAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAArapawlA 606
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  613 KAAKLEILQQQLqvaNETRDSAQtSVTQAqrekaeLSQKVEELRArvetACREQHEAQAQVAELEFQLQSEQQKA-TEKE 691
Cdd:COG3096    607 AQDALERLREQS---GEALADSQ-EVTAA------MQQLLERERE----ATVERDELAARKQALESQIERLSQPGgAEDP 672
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  692 RVAQEKDQL---------------------------------------QEQLQALK---ESLKVTKG----------SLE 719
Cdd:COG3096    673 RLLALAERLggvllseiyddvtledapyfsalygparhaivvpdlsavKEQLAGLEdcpEDLYLIEGdpdsfddsvfDAE 752
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  720 EEKRRAADALEEQQ------------------RCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARL-QQLGEAHQA 780
Cdd:COG3096    753 ELEDAVVVKLSDRQwrysrfpevplfgraareKRLEELRAERDELAEQYAKASFDVQKLQRLHQAFSQFVgGHLAVAFAP 832
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  781 ETEAlrqELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAMfQEQLMTLKEE-----CEKARQELQEAKEK 855
Cdd:COG3096    833 DPEA---ELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKL-LPQANLLADEtladrLEELREELDAAQEA 908
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  856 VAGIESHselqiSRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASR 935
Cdd:COG3096    909 QAFIQQH-----GKALAQLEPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGENS 983
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622865008  936 ELVK---------EPARAGDREPewLEEQQGR--QFCSTQAALQAMEREAEQMGNELER 983
Cdd:COG3096    984 DLNEklrarleqaEEARREAREQ--LRQAQAQysQYNQVLASLKSSRDAKQQTLQELEQ 1040
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
211-670 3.28e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 3.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  211 TPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQI-AMMQQRIDRLALLNEKQAASPLEPRELEELRDKNESLT 289
Cdd:TIGR00618  448 TCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKkAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT 527
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  290 MRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEWLEKQAQLEKELSTA 369
Cdd:TIGR00618  528 RRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAE 607
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  370 LQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAK 449
Cdd:TIGR00618  608 DMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQS 687
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  450 LLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELADLKQQAK 529
Cdd:TIGR00618  688 EKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNN 767
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  530 EEQAQLAQTLQQQEQASQGLRHQVEQLSS---SLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAAL--- 603
Cdd:TIGR00618  768 EEVTAALQTGAELSHLAAEIQFFNRLREEdthLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLgei 847
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622865008  604 -QQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQ 670
Cdd:TIGR00618  848 tHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYANVRLANQSEGR 915
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
522-749 4.48e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 4.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  522 ADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRrdhaQQLATAAEEREASLRERDA 601
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE----QELAALEAELAELEKEIAE 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  602 ALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEfqlq 681
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE---- 170
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622865008  682 seqqkaTEKERVAQEKDQLQEQ---LQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:COG4942    171 ------AERAELEALLAELEEEraaLEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
947-1625 4.92e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.81  E-value: 4.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  947 REPEWLEEQQGRQFCSTQAalQAMEREAEQMGNELERLRAALmeSQGQQQEERGQQEREVARLTQERGRAQADLALEKAA 1026
Cdd:TIGR00618  247 QKREAQEEQLKKQQLLKQL--RARIEELRAQEAVLEETQERI--NRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRS 322
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1027 KAELEMRLQNAL-NEQRVEFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGS 1105
Cdd:TIGR00618  323 RAKLLMKRAAHVkQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKEL 402
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1106 GAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSAL 1185
Cdd:TIGR00618  403 DILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIH 482
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1186 ASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEA------ERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAES 1259
Cdd:TIGR00618  483 LQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARqdidnpGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLK 562
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1260 EKSQKLEDRLRLLqaetASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAE-ELGQELKAWQEKFFQ 1338
Cdd:TIGR00618  563 EQMQEIQQSFSIL----TQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpEQDLQDVRLHLQQCS 638
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1339 KEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAE 1418
Cdd:TIGR00618  639 QELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDR 718
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1419 Q-ERTAQQLRAEKASYAEQLSMLKKAHGLLAEENR-GLGERANL-GRQFLEVELDQAREKYVQELAAVRADAETRLAEVQ 1495
Cdd:TIGR00618  719 EfNEIENASSSLGSDLAAREDALNQSLKELMHQARtVLKARTEAhFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDT 798
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1496 REAQSTARELEVMTAKYEGAK-VKVLEERQRFQEEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKA 1574
Cdd:TIGR00618  799 HLLKTLEAEIGQEIPSDEDILnLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622865008 1575 VQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKK 1625
Cdd:TIGR00618  879 NGINQIKIQFDGDALIKFLHEITLYANVRLANQSEGRFHGRYADSHVNARK 929
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
590-715 5.49e-05

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 47.74  E-value: 5.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  590 EEREASLRERDAALQQLEAlEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELS----------QKVEELRARV 659
Cdd:COG1566     79 TDLQAALAQAEAQLAAAEA-QLARLEAELGAEAEIAAAEAQLAAAQAQLDLAQRELERYQalykkgavsqQELDEARAAL 157
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622865008  660 ETACREQHEAQAQVAELEFQLQSEQQKATEKERVAqekdQLQEQLQALKESLKVTK 715
Cdd:COG1566    158 DAAQAQLEAAQAQLAQAQAGLREEEELAAAQAQVA----QAEAALAQAELNLARTT 209
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
210-795 5.52e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.63  E-value: 5.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  210 QTPQFQMRRLKKQLADERSNRDELELELAENR--KLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPRELEELRDKNES 287
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKhqQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELES 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  288 ltmRLHETLKQCQDLKTEKSQMDRKISQL---LEENGDLSFKLR----EFASHLQQLQDALNELTEEHSRATQEwlekQA 360
Cdd:pfam01576   83 ---RLEEEEERSQQLQNEKKKMQQHIQDLeeqLDEEEAARQKLQlekvTTEAKIKKLEEDILLLEDQNSKLSKE----RK 155
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  361 QLEKELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLE 440
Cdd:pfam01576  156 LLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  441 TEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQA------HGARLTAQVASLTSELT-TLNAT 513
Cdd:pfam01576  236 AQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAArnkaekQRRDLGEELEALKTELEdTLDTT 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  514 IQQQ------DQELADLKQQAKEEQaqlaqtlqqqeqasqglRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAqQLAT 587
Cdd:pfam01576  316 AAQQelrskrEQEVTELKKALEEET-----------------RSHEAQLQEMRQKHTQALEELTEQLEQAKRNKA-NLEK 377
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  588 AAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQvanetrdSAQTSVTQAQREKAELSQKVEELRARVETACREQH 667
Cdd:pfam01576  378 AKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQ-------ELQARLSESERQRAELAEKLSKLQSELESVSSLLN 450
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  668 EAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLV 747
Cdd:pfam01576  451 EAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMK 530
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1622865008  748 EQHKQEQKELEEEKAGRKGLearlqqlgeahQAETEALRQELAEAIAA 795
Cdd:pfam01576  531 KKLEEDAGTLEALEEGKKRL-----------QRELEALTQQLEEKAAA 567
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1521-1743 5.87e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 5.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1521 EERQRFQEEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQL 1600
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1601 SQKEQAAEHYKLQMEKAKTHYDAK--------KQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQAGLKTKEAEQT 1672
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLAlllspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622865008 1673 CRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSKLPR 1743
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250
Caldesmon pfam02029
Caldesmon;
550-856 6.19e-05

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 47.94  E-value: 6.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  550 RHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASL-----RERDAALQQLEALEKEKAAKLEILQQQL 624
Cdd:pfam02029   19 RRRQKEEEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEEAFLdrtakREERRQKRLQEALERQKEFDPTIADEKE 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  625 QVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAElefqlqSEQQKATEKERVAQEKDQLQEQL 704
Cdd:pfam02029   99 SVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEV------RQAEEEGEEEEDKSEEAEEVPTE 172
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  705 QALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETR-----SLVEQHKQEQKELEEEKAGRKGLEARL---QQLGE 776
Cdd:pfam02029  173 NFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGeeevtKLKVTTKRRQGGLSQSQEREEEAEVFLeaeQKLEE 252
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  777 AHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQ----QEEAQYGAMFQEQLMTLKEECEKARQELQEA 852
Cdd:pfam02029  253 LRRRRQEKESEEFEKLRQKQQEAELELEELKKKREERRKLLEEEEqrrkQEEAERKLREEEEKRRMKEEIERRRAEAAEK 332

                   ....
gi 1622865008  853 KEKV 856
Cdd:pfam02029  333 RQKL 336
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
789-1577 6.28e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 6.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  789 LAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAMFQEQLMTL----KEECEKARQELQEAKEKVAGIESHSE 864
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLddqwKEKRDELNGELSAADAAVAKDRSELE 325
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  865 LQISRqqnelvelhanlARALQQVqekevRAQKLADDLSTL---QEKMAATSKEVARLETLVRKAGEQQET----ASREL 937
Cdd:pfam12128  326 ALEDQ------------HGAFLDA-----DIETAAADQEQLpswQSELENLEERLKALTGKHQDVTAKYNRrrskIKEQN 388
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  938 VKEPARAGDREpEWLEEQQGRQFCSTQAALQAMEREAEqmgnelERLRAALMESQGQQQEERGQQEREVARLTQerGRAQ 1017
Cdd:pfam12128  389 NRDIAGIKDKL-AKIREARDRQLAVAEDDLQALESELR------EQLEAGKLEFNEEEYRLKSRLGELKLRLNQ--ATAT 459
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1018 ADLALEKAAKAELEMRLQNALNEQRVEFATLQEALAHAlteKEGKDQELVKLRGLEAAqikeLEELRQTMKQLKEQLakk 1097
Cdd:pfam12128  460 PELLLQLENFDERIERAREEQEAANAEVERLQSELRQA---RKRRDQASEALRQASRR----LEERQSALDELELQL--- 529
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1098 ekehasgsgaqseaagrTEPTGPKLEALRAEVSKLEqqcqqqqeqaDSLERSLEAERASRAERDSALETLQGQLEekare 1177
Cdd:pfam12128  530 -----------------FPQAGTLLHFLRKEAPDWE----------QSIGKVISPELLHRTDLDPEVWDGSVGGE----- 577
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1178 lghsqSALASVQRELAALrtKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVlekegeskelkrlvma 1257
Cdd:pfam12128  578 -----LNLYGVKLDLKRI--DVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGEL---------------- 634
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1258 eSEKSQKLEDRLRLLQaetasnsaRAAERSSALREEVQSLREEAEKQRVASENLRQE-LTSQAERAEELGQELKAWQEKf 1336
Cdd:pfam12128  635 -EKASREETFARTALK--------NARLDLRRLFDEKQSEKDKKNKALAERKDSANErLNSLEAQLKQLDKKHQAWLEE- 704
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1337 fQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQaagglraellraqRELGELIPLRQKV 1416
Cdd:pfam12128  705 -QKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYK-------------RDLASLGVDPDVI 770
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1417 AEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEenRGLGERANLGRQFLEVEldQAREKYVQELAAVRADAETRLAEVQR 1496
Cdd:pfam12128  771 AKLKREIRTLERKIERIAVRRQEVLRYFDWYQE--TWLQRRPRLATQLSNIE--RAISELQQQLARLIADTKLRRAKLEM 846
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1497 EAQSTARELEVMTAKYEGAKVkVLEERQRFqeekqKLTAQVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAVQ 1576
Cdd:pfam12128  847 ERKASEKQQVRLSENLRGLRC-EMSKLATL-----KEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVI 920

                   .
gi 1622865008 1577 A 1577
Cdd:pfam12128  921 A 921
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
276-507 6.29e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 6.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  276 RELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSratqew 355
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE------ 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  356 lEKQAQLEKELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQekgevlgDVLQLETLKQEAATLAANNTQLQAR 435
Cdd:COG4942    101 -AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA-------RREQAEELRADLAELAALRAELEAE 172
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622865008  436 VETLETEQGQQEakllAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQahgaRLTAQVASLTSEL 507
Cdd:COG4942    173 RAELEALLAELE----EERAALEALKAERQKLLARLEKELAELAAELAELQQEAE----ELEALIARLEAEA 236
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
378-604 6.29e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 6.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  378 EKNEILQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDHF 457
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  458 EEEKQQLSSLIANLQ--------------SSISNLSQAKEELEQASQAHGARLTAQVASLTsELTTLNATIQQQDQELAD 523
Cdd:COG4942    100 EAQKEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLA-ELAALRAELEAERAELEA 178
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  524 LKQQAKEEQAQLAQTLQQQEQasqglrhQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAAL 603
Cdd:COG4942    179 LLAELEEERAALEALKAERQK-------LLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251

                   .
gi 1622865008  604 Q 604
Cdd:COG4942    252 K 252
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
679-917 8.38e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 8.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  679 QLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRR---AADALEEQQRCISELKAETRSLVEQHKQEQK 755
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiaaLARRIRALEQELAALEAELAELEKEIAELRA 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  756 ELEEEKAGRKGLEARLQQLGEAHQAETEALRQELAEAIAAQrtaeseceQLVKEVAAWRERYEESQQEEaqygamfQEQL 835
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRL--------QYLKYLAPARREQAEELRAD-------LAEL 162
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  836 MTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKE 915
Cdd:COG4942    163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242

                   ..
gi 1622865008  916 VA 917
Cdd:COG4942    243 TP 244
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
313-990 8.65e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 8.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  313 ISQLLEENGDLSFKLREFASHLQQLQ-DALNELTEEHSRATQEWLEKQAQLEKELSTALqdkkcleekneILQGKLSqle 391
Cdd:PRK03918    73 IELKFEKNGRKYRIVRSFNRGESYLKyLDGSEVLEEGDSSVREWVERLIPYHVFLNAIY-----------IRQGEID--- 138
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  392 ehlALLRENPPQEKgeVLGDVLQLETLKQEAATLAANNTQLQARVETLETE---QGQQEAKLLAERDHFEEEKQQLSSLI 468
Cdd:PRK03918   139 ---AILESDESREK--VVRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFikrTENIEELIKEKEKELEEVLREINEIS 213
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  469 ANLQSSISNLSQAKEELEQASQAHG--ARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQAS 546
Cdd:PRK03918   214 SELPELREELEKLEKEVKELEELKEeiEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAE 293
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  547 QGLRhqVEQLSSSLKQKEQQLKEVAEKQEvtrrdhaqQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQV 626
Cdd:PRK03918   294 EYIK--LSEFYEEYLDELREIEKRLSRLE--------EEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHEL 363
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  627 ANEtrdsAQTSVTQAQREKAELSQK-VEELRARVETACREQHEAQAQVAELefqlqsEQQKATEKERVAQEKDQLQEqLQ 705
Cdd:PRK03918   364 YEE----AKAKKEELERLKKRLTGLtPEKLEKELEELEKAKEEIEEEISKI------TARIGELKKEIKELKKAIEE-LK 432
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  706 ALKESLKVTKGSLEEEKRraADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGlEARLQQLGEAHQaETEAL 785
Cdd:PRK03918   433 KAKGKCPVCGRELTEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK-ESELIKLKELAE-QLKEL 508
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  786 RQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSEL 865
Cdd:PRK03918   509 EEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVE 588
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  866 QISRQQNELVELHANLARALQQVQEKEVRAQKLADdlstLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAG 945
Cdd:PRK03918   589 ELEERLKELEPFYNEYLELKDAEKELEREEKELKK----LEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEEL 664
                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1622865008  946 DREPEWLEeqqgRQFCSTQAALQAMEREAEQMGNELERLRAALME 990
Cdd:PRK03918   665 REEYLELS----RELAGLRAELEELEKRREEIKKTLEKLKEELEE 705
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
326-607 1.36e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  326 KLREFASHLQQLQDALNELTEEHSRATQEwlEKQAQLEKELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQek 405
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAE--LDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDD-- 686
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  406 gevlgdvlqLETLKQEAATLAANNTQLQARVETLETEQGQQEakllAERDHFEEEKQQLSSLIANLQSSISNLSQAKEEl 485
Cdd:COG4913    687 ---------LAALEEQLEELEAELEELEEELDELKGEIGRLE----KELEQAEEELDELQDRLEAAEDLARLELRALLE- 752
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  486 EQASQAHGARLTAQV-ASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSS-LKQK 563
Cdd:COG4913    753 ERFAAALGDAVERELrENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDgLPEY 832
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1622865008  564 EQQLKEVAEKQEVTRRDH-AQQLATAAEEREASLRERDAALQQLE 607
Cdd:COG4913    833 EERFKELLNENSIEFVADlLSKLRRAIREIKERIDPLNDSLKRIP 877
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
218-750 1.40e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.04  E-value: 1.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  218 RLKKQLADERSNRDELELELAENRKLLtEKDAQIAMMqqrIDRLAllnekqaasplepRELEELRDKNESLTMRLHETLK 297
Cdd:pfam15921  378 QLQKLLADLHKREKELSLEKEQNKRLW-DRDTGNSIT---IDHLR-------------RELDDRNMEVQRLEALLKAMKS 440
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  298 QCQdlktekSQMDRKISQLLEENGDLSfKLREFASHLQQLQDALNELTEEHSrATQEWLEKQAQLEKELSTALQDKkclE 377
Cdd:pfam15921  441 ECQ------GQMERQMAAIQGKNESLE-KVSSLTAQLESTKEMLRKVVEELT-AKKMTLESSERTVSDLTASLQEK---E 509
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  378 EKNEILQGKLSQLEEHLALlrenppqekgevlgDVLQLETLKQEAATLaannTQLQARVETLETEqgqqeaklLAERDhf 457
Cdd:pfam15921  510 RAIEATNAEITKLRSRVDL--------------KLQELQHLKNEGDHL----RNVQTECEALKLQ--------MAEKD-- 561
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  458 eeekqqlsSLIANLQSSISNLSQ---AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKE---E 531
Cdd:pfam15921  562 --------KVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDlelE 633
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  532 QAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQlataAEEREASLRERDAALQQLEALEK 611
Cdd:pfam15921  634 KVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNK----SEEMETTTNKLKMQLKSAQSELE 709
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  612 EKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSeqqKATEKE 691
Cdd:pfam15921  710 QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELST---VATEKN 786
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622865008  692 RVAQEKDQLQEQLQALKESLKVTKGSLEeekrRAADALEEQQRCISELKAETRSLVEQH 750
Cdd:pfam15921  787 KMAGELEVLRSQERRLKEKVANMEVALD----KASLQFAECQDIIQRQEQESVRLKLQH 841
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
645-1617 1.41e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.09  E-value: 1.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  645 KAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQE-KDQLQEQLQALKESLKVTKGSLEEEKR 723
Cdd:pfam01576   10 KEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEmRARLAARKQELEEILHELESRLEEEEE 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  724 RAADALEEQQRCISELKAETRSLVEQHKQEQK---ELEEEKAGRKGLEARLQQLgEAHQAETEALRQELAEAIAAQRTAE 800
Cdd:pfam01576   90 RSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKlqlEKVTTEAKIKKLEEDILLL-EDQNSKLSKERKLLEERISEFTSNL 168
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  801 SECEQLVKEVAAWRERYEesqqeeaqygAMFQEQLMTLKEEcEKARQELQEAKEKVAGIESHSELQISRQQNELVELHAN 880
Cdd:pfam01576  169 AEEEEKAKSLSKLKNKHE----------AMISDLEERLKKE-EKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQ 237
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  881 LARALQQVQEKEVRAQK--------------LADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASREL--------- 937
Cdd:pfam01576  238 LAKKEEELQAALARLEEetaqknnalkkireLEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELedtldttaa 317
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  938 -----------VKEPARAGDREPEWLEEQQGRQFCSTQAALQAMEREAEQmgneLERLRAALMESQGQQQEERGQQEREV 1006
Cdd:pfam01576  318 qqelrskreqeVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQ----AKRNKANLEKAKQALESENAELQAEL 393
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1007 ARLTQ-----ERGRAQADLAL-EKAAKAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKEL 1080
Cdd:pfam01576  394 RTLQQakqdsEHKRKKLEGQLqELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDT 473
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1081 EELRQTMKQLKEQLAKK----EKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLErsleaERAS 1156
Cdd:pfam01576  474 QELLQEETRQKLNLSTRlrqlEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALE-----EGKK 548
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1157 RAERDsaLETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSI 1236
Cdd:pfam01576  549 RLQRE--LEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDR 626
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1237 LNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAET---------ASNSARAAERSS-ALREEVQSLR---EEAEK 1303
Cdd:pfam01576  627 AEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMedlvsskddVGKNVHELERSKrALEQQVEEMKtqlEELED 706
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1304 QRVASEN--LRQELTSQAERA---------EELGQELK------------AWQEKFFQKEQALST---LQLEHTSTQALV 1357
Cdd:pfam01576  707 ELQATEDakLRLEVNMQALKAqferdlqarDEQGEEKRrqlvkqvreleaELEDERKQRAQAVAAkkkLELDLKELEAQI 786
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1358 SELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQREL----GELIPLRQKVAEQERTAQQLRAEKASY 1433
Cdd:pfam01576  787 DAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLknleAELLQLQEDLAASERARRQAQQERDEL 866
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1434 AEQLSMLKKAHGLLAEENRGLgeranlgrqflEVELDQAREKYVQELAAVRAdaetrLAEVQREAQSTARELEVMTAKYE 1513
Cdd:pfam01576  867 ADEIASGASGKSALQDEKRRL-----------EARIAQLEEELEEEQSNTEL-----LNDRLRKSTLQVEQLTTELAAER 930
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1514 GAKVKVLEERQRFQEEKQKLTAQVEQLEVFQREQTK-QVEELRKKLADS----DQASKVQQQKLKAVQaqggesqqeaqR 1588
Cdd:pfam01576  931 STSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKsSIAALEAKIAQLeeqlEQESRERQAANKLVR-----------R 999
                         1050      1060
                   ....*....|....*....|....*....
gi 1622865008 1589 LQARLNELQAQLSQKEQAAEHYKLQMEKA 1617
Cdd:pfam01576 1000 TEKKLKEVLLQVEDERRHADQYKDQAEKG 1028
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1047-1501 1.65e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1047 TLQEALAHALTEK-EGKDQELVKLRG----LEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPK 1121
Cdd:COG4717     38 TLLAFIRAMLLERlEKEADELFKPQGrkpeLNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREE 117
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1122 LEALR---------AEVSKLEQQCQQQQEQADSLERSLEAER---ASRAERDSALETLQGQLEEKARELG-HSQSALASV 1188
Cdd:COG4717    118 LEKLEkllqllplyQELEALEAELAELPERLEELEERLEELReleEELEELEAELAELQEELEELLEQLSlATEEELQDL 197
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1189 QRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSIL-NRQVLEKEGESKELKRLVMAESEKSQKLED 1267
Cdd:COG4717    198 AEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKeARLLLLIAAALLALLGLGGSLLSLILTIAG 277
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1268 RLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTS-------QAERAEELGQELKAWQEKFFQKE 1340
Cdd:COG4717    278 VLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAlglppdlSPEELLELLDRIEELQELLREAE 357
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1341 QALSTLQLEHtsTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAgglrAELLRAQRELGELIPLRQKVAEQE 1420
Cdd:COG4717    358 ELEEELQLEE--LEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEEL----EEQLEELLGELEELLEALDEEELE 431
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1421 RTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS 1500
Cdd:COG4717    432 EELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYRE 511

                   .
gi 1622865008 1501 T 1501
Cdd:COG4717    512 E 512
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
335-616 1.71e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.93  E-value: 1.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  335 QQLQDALNELTEEHSRATQEWLEKQAqlekelstalqdkkcleeknEILQGKLSQLEEHLALLRENppqekgevlgdvLQ 414
Cdd:COG3206    159 EAYLEQNLELRREEARKALEFLEEQL--------------------PELRKELEEAEAALEEFRQK------------NG 206
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  415 LETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANlqssiSNLSQAKEELeqasqahgA 494
Cdd:COG3206    207 LVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQS-----PVIQQLRAQL--------A 273
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  495 RLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEqasQGLRHQVEQLSSSLKQKEQQLKEVAEKQ 574
Cdd:COG3206    274 ELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAEL---EALQAREASLQAQLAQLEARLAELPELE 350
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1622865008  575 evtrrdhaQQLATAAEEREASLRERDAALQQLEALEKEKAAK 616
Cdd:COG3206    351 --------AELRRLEREVEVARELYESLLQRLEEARLAEALT 384
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
414-740 2.02e-04

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 46.37  E-value: 2.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  414 QLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSIS---------NLSQAKEE 484
Cdd:PRK04778   120 DIEQILEELQELLESEEKNREEVEQLKDLYRELRKSLLANRFSFGPALDELEKQLENLEEEFSqfveltesgDYVEAREI 199
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  485 LEQAsQAHGARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEeqaqlaqtlqqqeqasQGLRHQVEQLSSSLKQKE 564
Cdd:PRK04778   200 LDQL-EEELAALEQIMEEIPELLKELQTELPDQLQELKAGYRELVE----------------EGYHLDHLDIEKEIQDLK 262
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  565 QQLKEVAEKQEVTRRDHAQQLATAAEEReaslrerdaaLQQL-EALEKEKAAKleilqqqlQVANETRDSAQTSVTQAQR 643
Cdd:PRK04778   263 EQIDENLALLEELDLDEAEEKNEEIQER----------IDQLyDILEREVKAR--------KYVEKNSDTLPDFLEHAKE 324
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  644 EKAELSQKVEELRARVETACRE---QHEAQAQVAELEFQLQSEQQKATEK--------ERVAQEKDQLqEQLQALKESLK 712
Cdd:PRK04778   325 QNKELKEEIDRVKQSYTLNESElesVRQLEKQLESLEKQYDEITERIAEQeiayselqEELEEILKQL-EEIEKEQEKLS 403
                          330       340
                   ....*....|....*....|....*...
gi 1622865008  713 VTKGSLEEEKRRAADALEEQQRCISELK 740
Cdd:PRK04778   404 EMLQGLRKDELEAREKLERYRNKLHEIK 431
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
227-655 2.37e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.48  E-value: 2.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  227 RSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLAllnekqaasplepRELEELRDKNESLTMRLHETLKQCQDLKTEK 306
Cdd:COG3096    277 ANERRELSERALELRRELFGARRQLAEEQYRLVEMA-------------RELEELSARESDLEQDYQAASDHLNLVQTAL 343
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  307 SQMDrKISQLLEENGDLSFKLREfashlqqLQDALNELTEEHSRAtQEWLEkQAQLE-KELSTALQDkkcLEEKNEILQG 385
Cdd:COG3096    344 RQQE-KIERYQEDLEELTERLEE-------QEEVVEEAAEQLAEA-EARLE-AAEEEvDSLKSQLAD---YQQALDVQQT 410
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  386 KLSQLEEHLALLrenppqEKGEVLgdvLQLETLKQEAA--TLAANNTQLQARVET-LETEQGQQEAKllAERDHFEEEKQ 462
Cdd:COG3096    411 RAIQYQQAVQAL------EKARAL---CGLPDLTPENAedYLAAFRAKEQQATEEvLELEQKLSVAD--AARRQFEKAYE 479
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  463 QLSSLIANLQSSISNlSQAKEELEQA-SQAHgarLTAQVASLTSELTTLNATIQQQdqeladlkQQAKEEQAQLAQTLQQ 541
Cdd:COG3096    480 LVCKIAGEVERSQAW-QTARELLRRYrSQQA---LAQRLQQLRAQLAELEQRLRQQ--------QNAERLLEEFCQRIGQ 547
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  542 QEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRR--DHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEI 619
Cdd:COG3096    548 QLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQqlEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQE 627
                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1622865008  620 LQQQLQVANETRDSAQTSVTQAQREKAELSQKVEEL 655
Cdd:COG3096    628 VTAAMQQLLEREREATVERDELAARKQALESQIERL 663
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
1746-2016 2.38e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.32  E-value: 2.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1746 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARSQA--PLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKL 1823
Cdd:PHA03307   192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIW 270
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1824 DVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARLSSPdyGNSALLSLPGYRP-----TTRSSARRSQAGVSSGAPPG 1898
Cdd:PHA03307   271 EASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPS--SPRASSSSSSSREsssssTSSSSESSRGAAVSPGPSPS 348
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1899 RNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlslgtitdeemktgdpqETLRRASMQ---PIQI 1975
Cdd:PHA03307   349 RS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARAAvagRARR 400
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1622865008 1976 AEGTGITTRQQRKRVSLEPHQGPGTPESKkatscfPRPMTP 2016
Cdd:PHA03307   401 RDATGRFPAGRPRPSPLDAGAASGAFYAR------YPLLTP 435
mukB PRK04863
chromosome partition protein MukB;
1380-1725 2.44e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.49  E-value: 2.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1380 RHREELEQSKQAAGGLRAELLRAQRELGE----LIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAhglLAEENRglG 1455
Cdd:PRK04863   276 RHANERRVHLEEALELRRELYTSRRQLAAeqyrLVEMARELAELNEAESDLEQDYQAASDHLNLVQTA---LRQQEK--I 350
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1456 ERAnlgrqflEVELDQAREKyVQELAAVRADAETRLAEvqREAQSTARELEVMTAKYEGAKVK----VLEER-------- 1523
Cdd:PRK04863   351 ERY-------QADLEELEER-LEEQNEVVEEADEQQEE--NEARAEAAEEEVDELKSQLADYQqaldVQQTRaiqyqqav 420
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1524 QRFQEEKQ----------KLTAQVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGE------------ 1581
Cdd:PRK04863   421 QALERAKQlcglpdltadNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEvsrseawdvare 500
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1582 -------SQQEAQRLQARLNELQA--QLSQKEQAAEHYKLQMEK-AKTHYDAKKQQNQELQEQLQSLEHLQKENKELRAE 1651
Cdd:PRK04863   501 llrrlreQRHLAEQLQQLRMRLSEleQRLRQQQRAERLLAEFCKrLGKNLDDEDELEQLQEELEARLESLSESVSEARER 580
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1652 AERLGHELQQAGLKTKEAEQTCRH-LTAQ--VRSLEAQVAHAD-----------QQLRDLGKFQVATDALKSRepqaKPQ 1717
Cdd:PRK04863   581 RMALRQQLEQLQARIQRLAARAPAwLAAQdaLARLREQSGEEFedsqdvteymqQLLERERELTVERDELAAR----KQA 656

                   ....*...
gi 1622865008 1718 LDLSIDSL 1725
Cdd:PRK04863   657 LDEEIERL 664
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
231-864 2.45e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.50  E-value: 2.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  231 DELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPRELEELRdknesltmRLHETLKQCQDLKTEKSQMD 310
Cdd:TIGR00618  249 REAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIK--------AVTQIEQQAQRIHTELQSKM 320
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  311 RKISQLLEENGDL---SFKLREFASHLQQLQDALNELTEEHSRAT--QEWLEKQAQLEKELSTALQDKKCLEEKNEILQG 385
Cdd:TIGR00618  321 RSRAKLLMKRAAHvkqQSSIEEQRRLLQTLHSQEIHIRDAHEVATsiREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCK 400
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  386 KLSQLEEHLA-----LLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEE 460
Cdd:TIGR00618  401 ELDILQREQAtidtrTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQ 480
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  461 KQQLSSLIANLQSSISNLSQAKEELEQASQAH---GARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQ 537
Cdd:TIGR00618  481 IHLQETRKKAVVLARLLELQEEPCPLCGSCIHpnpARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRAS 560
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  538 TLQQQEQASQGLRHQVEQLSSS------LKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEK 611
Cdd:TIGR00618  561 LKEQMQEIQQSFSILTQCDNRSkedipnLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQE 640
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  612 EKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQ-KVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEK 690
Cdd:TIGR00618  641 LALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQlALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREF 720
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  691 ERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRA--ADALEEQQRCISELKAETRSLVEQHKQEQKELEeekagRKGLE 768
Cdd:TIGR00618  721 NEIENASSSLGSDLAAREDALNQSLKELMHQARTVlkARTEAHFNNNEEVTAALQTGAELSHLAAEIQFF-----NRLRE 795
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  769 ARLQQLgeahqAETEALRQELAEAIAAQRTAesECEQLVKEVAAWRERYEESQQEeaqygamfQEQLMTLKEECEKARQE 848
Cdd:TIGR00618  796 EDTHLL-----KTLEAEIGQEIPSDEDILNL--QCETLVQEEEQFLSRLEEKSAT--------LGEITHQLLKYEECSKQ 860
                          650
                   ....*....|....*.
gi 1622865008  849 LQEAKEKVAGIESHSE 864
Cdd:TIGR00618  861 LAQLTQEQAKIIQLSD 876
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
300-531 2.48e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  300 QDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEwlekQAQLEKELSTalqdkkcLEEK 379
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE----LAALEAELAE-------LEKE 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  380 NEILQGKLSQLEEHLA-LLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEaKLLAERDHFE 458
Cdd:COG4942     92 IAELRAELEAQKEELAeLLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA-ELAALRAELE 170
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622865008  459 EEKQQLSSLIANLQssisnlsQAKEELEQASQAHG---ARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEE 531
Cdd:COG4942    171 AERAELEALLAELE-------EERAALEALKAERQkllARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
mukB PRK04863
chromosome partition protein MukB;
840-1703 2.55e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.49  E-value: 2.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  840 EECEKARQELQEAKEkvagieshselQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKE---V 916
Cdd:PRK04863   286 EEALELRRELYTSRR-----------QLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIeryQ 354
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  917 ARLETLVRKAGEQQETasRELVKEPARAGDREPEWLEEQQGR---QFCSTQAALQAMEREAEQMGNELERLRAAlmesqg 993
Cdd:PRK04863   355 ADLEELEERLEEQNEV--VEEADEQQEENEARAEAAEEEVDElksQLADYQQALDVQQTRAIQYQQAVQALERA------ 426
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  994 QQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELVKLRGLE 1073
Cdd:PRK04863   427 KQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRRLR 506
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1074 AAQIkeleeLRQTMKQLKEQLAKKEKEHASgsgaQSEAagrteptgpklEALRAEVSKLEQQCQQQQEQADSLERSLEAE 1153
Cdd:PRK04863   507 EQRH-----LAEQLQQLRMRLSELEQRLRQ----QQRA-----------ERLLAEFCKRLGKNLDDEDELEQLQEELEAR 566
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1154 RASraerdsaletlqgqLEEKARELGHSQSALasvQRELAALRTKVQDHSKAEDEW-KAQVARGRQEAERKNSLISSleE 1232
Cdd:PRK04863   567 LES--------------LSESVSEARERRMAL---RQQLEQLQARIQRLAARAPAWlAAQDALARLREQSGEEFEDS--Q 627
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1233 EVSILNRQVLEKEGESKELKRLVmaESEKSQKLEDRLRLLQAETASNS--ARAAERSSA-----LREEVqSLrEEAEKQR 1305
Cdd:PRK04863   628 DVTEYMQQLLERERELTVERDEL--AARKQALDEEIERLSQPGGSEDPrlNALAERFGGvllseIYDDV-SL-EDAPYFS 703
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1306 VASENLRQELtsqaeraeeLGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHRE-- 1383
Cdd:PRK04863   704 ALYGPARHAI---------VVPDLSDAAEQLAGLEDCPEDLYLIEGDPDSFDDSVFSVEELEKAVVVKIADRQWRYSRfp 774
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1384 ELEQSKQAAGGLRAELLRAQREL--GELIPLRQKVAEQERTAQQLRAEKASYAeQLSMLKKAHGLLAEENRGLGEranlg 1461
Cdd:PRK04863   775 EVPLFGRAAREKRIEQLRAEREElaERYATLSFDVQKLQRLHQAFSRFIGSHL-AVAFEADPEAELRQLNRRRVE----- 848
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1462 rqfLEVELDQAREKYVQELAAVRAdAETRLAEVQR-EAQSTARELEVMTAKYEG--AKVKVLEERQRFQEEKQKLTAQVE 1538
Cdd:PRK04863   849 ---LERALADHESQEQQQRSQLEQ-AKEGLSALNRlLPRLNLLADETLADRVEEirEQLDEAEEAKRFVQQHGNALAQLE 924
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1539 QLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAV-------------QAQG--GESQQEAQRLQARLNELQA----- 1598
Cdd:PRK04863   925 PIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALtevvqrrahfsyeDAAEmlAKNSDLNEKLRQRLEQAEQertra 1004
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1599 --QLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLQSLEHLQKENKELRAEA--ERLGHELQQAGLKTKEAEQTCR 1674
Cdd:PRK04863  1005 reQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARArrDELHARLSANRSRRNQLEKQLT 1084
                          890       900
                   ....*....|....*....|....*....
gi 1622865008 1675 HLTAQVRSLEAQVAHADQQLRDLGKFQVA 1703
Cdd:PRK04863  1085 FCEAEMDNLTKKLRKLERDYHEMREQVVN 1113
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
554-1351 2.67e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.26  E-value: 2.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  554 EQLSSSLKQKEQQLKEVAEKQEVTRRDHaqqlataaEEREASLRERDAALQ-QLEALEKEKAAKLEILQQQLQVANETRD 632
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELH--------EKQKFYLRQSVIDLQtKLQEMQMERDAMADIRRRESQSQEDLRN 145
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  633 SAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEK--ERVAQEKDQLQEQLQALKES 710
Cdd:pfam15921  146 QLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKiyEHDSMSTMHFRSLGSAISKI 225
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  711 LKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHkqeqkeleeekagrkglEARLQQLGEAHQAETEALRQELA 790
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQH-----------------QDRIEQLISEHEVEITGLTEKAS 288
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  791 EAIAAQRTAESECEQLvkevaawreryeesQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQ 870
Cdd:pfam15921  289 SARSQANSIQSQLEII--------------QEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLA 354
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  871 QNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARL-----------ETLVRKAGEQQETASRelVK 939
Cdd:pfam15921  355 NSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLwdrdtgnsitiDHLRRELDDRNMEVQR--LE 432
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  940 EPARAGDREPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRaALMESQGQQQEERGQQEREVARLTQERGRAQAD 1019
Cdd:pfam15921  433 ALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLR-KVVEELTAKKMTLESSERTVSDLTASLQEKERA 511
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1020 LALEKAAKAELEMRLQNALNEQRvEFATLQEALAHALTEKEGkdqelvkLRGLEAAQIKELEELRQTMKQLKEQLAKKEK 1099
Cdd:pfam15921  512 IEATNAEITKLRSRVDLKLQELQ-HLKNEGDHLRNVQTECEA-------LKLQMAEKDKVIEILRQQIENMTQLVGQHGR 583
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1100 ehASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRA--ERDSALETLQGQLEEKARE 1177
Cdd:pfam15921  584 --TAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAgsERLRAVKDIKQERDQLLNE 661
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1178 LGHSQSALASVQRELAAL----RTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEE------EVSI-LNRQVLEKEG 1246
Cdd:pfam15921  662 VKTSRNELNSLSEDYEVLkrnfRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGsdghamKVAMgMQKQITAKRG 741
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1247 ESKELKRLVMAESEKSQKLEDRLRLLQAEtasnSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELG 1326
Cdd:pfam15921  742 QIDALQSKIQFLEEAMTNANKEKHFLKEE----KNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKAS 817
                          810       820
                   ....*....|....*....|....*
gi 1622865008 1327 QELKAWQEKFFQKEQALSTLQLEHT 1351
Cdd:pfam15921  818 LQFAECQDIIQRQEQESVRLKLQHT 842
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
1215-1655 2.67e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 46.27  E-value: 2.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1215 RGRQEAERK-NSLISSLEEEVSILN------RQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERS 1287
Cdd:pfam05557   27 RARIELEKKaSALKRQLDRESDRNQelqkriRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLADAREVI 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1288 SALREEVQSLREEAEKQRvasenlrQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQlehTSTQALVSELLPAKHLc 1367
Cdd:pfam05557  107 SCLKNELSELRRQIQRAE-------LELQSTNSELEELQERLDLLKAKASEAEQLRQNLE---KQQSSLAEAEQRIKEL- 175
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1368 qqlqaeqaaaeKRHREELEQSKQAAGGLRAELLRaqrelgeliplrqkVAEQERTAQQLRAEKasyaEQLSMLKKAHGLL 1447
Cdd:pfam05557  176 -----------EFEIQSQEQDSEIVKNSKSELAR--------------IPELEKELERLREHN----KHLNENIENKLLL 226
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1448 AEENRGLgeRANLGRQfleveldqarEKYVQELAAVRADAETRLAEVQrEAQSTARELEVMTAKYEGAKVKVLEERQR-- 1525
Cdd:pfam05557  227 KEEVEDL--KRKLERE----------EKYREEAATLELEKEKLEQELQ-SWVKLAQDTGLNLRSPEDLSRRIEQLQQRei 293
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1526 -FQEEKQKLTAQVEQLEVFQRE-------QTKQVEELRKKLADSD-QASKVQQQKLKAVQAQGG---------------- 1580
Cdd:pfam05557  294 vLKEENSSLTSSARQLEKARREleqelaqYLKKIEDLNKKLKRHKaLVRRLQRRVLLLTKERDGyrailesydkeltmsn 373
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1581 ----------ESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLQSLEH--LQKENKEL 1648
Cdd:pfam05557  374 yspqllerieEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYSKEEVdsLRRKLETL 453

                   ....*..
gi 1622865008 1649 RAEAERL 1655
Cdd:pfam05557  454 ELERQRL 460
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
414-713 2.78e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 45.66  E-value: 2.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  414 QLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHg 493
Cdd:COG4372     32 QLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEA- 110
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  494 ARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEK 573
Cdd:COG4372    111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLK 190
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  574 QEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVE 653
Cdd:COG4372    191 EANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVE 270
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  654 ELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKV 713
Cdd:COG4372    271 KDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLEL 330
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1315-1578 3.16e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1315 LTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELlpakhlcqqlqaeqaaaekrhREELEQSKQAAGG 1394
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL---------------------ERRIAALARRIRA 73
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1395 LRAELLRAQRELGELIplrqkvAEQERTAQQLRAEKASYAEQLSMLKKAhgllaeenrGLGERANLGRQFLEVELDQARE 1474
Cdd:COG4942     74 LEQELAALEAELAELE------KEIAELRAELEAQKEELAELLRALYRL---------GRQPPLALLLSPEDFLDAVRRL 138
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1475 KYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEEKQKLTAQVEQLEVFQREQTKQVEEL 1554
Cdd:COG4942    139 QYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL 218
                          250       260
                   ....*....|....*....|....
gi 1622865008 1555 RKKLADSDQASKVQQQKLKAVQAQ 1578
Cdd:COG4942    219 QQEAEELEALIARLEAEAAAAAER 242
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
768-1037 3.34e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 3.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  768 EARLQQLGEAHQAETEALRQELAEAIAAQRTAES-------------ECEQLVKEVA-AWRERYEESQQEEAQYGAMF-Q 832
Cdd:COG3206    102 KLNLDEDPLGEEASREAAIERLRKNLTVEPVKGSnvieisytspdpeLAAAVANALAeAYLEQNLELRREEARKALEFlE 181
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  833 EQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQneLVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAAT 912
Cdd:COG3206    182 EQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQ--LSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  913 SKevarlETLVRKAGEQQETASRELVKEPARAGDREP-------------EWLEEQQGRQFCSTQAALQAMEREAEQMGN 979
Cdd:COG3206    260 LQ-----SPVIQQLRAQLAELEAELAELSARYTPNHPdvialraqiaalrAQLQQEAQRILASLEAELEALQAREASLQA 334
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  980 ELERLRAALMEsqgqqqeeRGQQEREVARLTQERGRAQA--DLALEKAAKAELEMRLQNA 1037
Cdd:COG3206    335 QLAQLEARLAE--------LPELEAELRRLEREVEVARElyESLLQRLEEARLAEALTVG 386
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
587-802 3.52e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 3.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  587 TAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQ 666
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  667 HEAQAQVAELEFQLQSEQ-----QKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEK---RRAADALEEQQRCISE 738
Cdd:COG3883     96 YRSGGSVSYLDVLLGSESfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLaelEALKAELEAAKAELEA 175
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622865008  739 LKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQAETEALRQELAEAIAAQRTAESE 802
Cdd:COG3883    176 QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 239
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1016-1255 3.60e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1016 AQADLAleKAAKAELEmRLQNALNEQRVEFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLA 1095
Cdd:COG4942     17 AQADAA--AEAEAELE-QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1096 KKEKEhasgsgaqseaagrteptgpkLEALRAEVSKLeQQCQQQQEQADSLERSLEAERASRAERDSA-LETLQGQLEEK 1174
Cdd:COG4942     94 ELRAE---------------------LEAQKEELAEL-LRALYRLGRQPPLALLLSPEDFLDAVRRLQyLKYLAPARREQ 151
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1175 ARELGHSQSALASVQRELAALRTKVQdhsKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRL 1254
Cdd:COG4942    152 AEELRADLAELAALRAELEAERAELE---ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228

                   .
gi 1622865008 1255 V 1255
Cdd:COG4942    229 I 229
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
202-855 3.78e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.87  E-value: 3.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  202 ASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLA------------------- 262
Cdd:pfam05483   73 SEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSlkleeeiqenkdlikenna 152
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  263 ------LLNEKQAASPLEPRE-------------------------LEELRDKNESLTMRLHETLKQC--------QDLK 303
Cdd:pfam05483  153 trhlcnLLKETCARSAEKTKKyeyereetrqvymdlnnniekmilaFEELRVQAENARLEMHFKLKEDhekiqhleEEYK 232
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  304 TEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEE---HSRATQEWLEKQAQLEKEL-------STALQDK 373
Cdd:pfam05483  233 KEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKtklQDENLKELIEKKDHLTKELedikmslQRSMSTQ 312
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  374 KCLEEKNEILQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLET--------LKQEAATLAANNTQLQARVETLETEQGQ 445
Cdd:pfam05483  313 KALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEAttcsleelLRTEQQRLEKNEDQLKIITMELQKKSSE 392
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  446 QEaKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAK---EELEQASQAHGARLTA---QVASLTSELTTLNATIQQQDQ 519
Cdd:pfam05483  393 LE-EMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEkiaEELKGKEQELIFLLQArekEIHDLEIQLTAIKTSEEHYLK 471
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  520 ELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQqlATAAEEREASLREr 599
Cdd:pfam05483  472 EVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQ--IENLEEKEMNLRD- 548
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  600 daalqQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQaqvaelefq 679
Cdd:pfam05483  549 -----ELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELH--------- 614
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  680 lqsEQQKATEKERVAQEKdqlqeQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEE 759
Cdd:pfam05483  615 ---QENKALKKKGSAENK-----QLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADE 686
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  760 EKAGRKGLEARLQqlgeahqaetealrQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAMFQEQLMTLK 839
Cdd:pfam05483  687 AVKLQKEIDKRCQ--------------HKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIK 752
                          730
                   ....*....|....*.
gi 1622865008  840 EECEKARQELQEAKEK 855
Cdd:pfam05483  753 AELLSLKKQLEIEKEE 768
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
207-929 3.94e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.81  E-value: 3.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  207 DILQTPQF--QMRRLKKQLADERSNRDELELELaenRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPRELEELRDK 284
Cdd:TIGR00606  177 EIFSATRYikALETLRQVRQTQGQKVQEHQMEL---KYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNR 253
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  285 NEsltmRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFashLQQLQDALNELTEEHSRATQEWLEKQAQLEK 364
Cdd:TIGR00606  254 LK----EIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKV---FQGTDEQLNDLYHNHQRTVREKERELVDCQR 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  365 ELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQlqaRVETLETEQG 444
Cdd:TIGR00606  327 ELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIK---NFHTLVIERQ 403
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  445 QQEAKLLAErdhfeeekqqlssLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELADL 524
Cdd:TIGR00606  404 EDEAKTAAQ-------------LCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSS 470
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  525 KQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQL--KEVAEKQEVTRRDH-----AQQLATAAEEREASLR 597
Cdd:TIGR00606  471 DRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLdrKLRKLDQEMEQLNHhtttrTQMEMLTKDKMDKDEQ 550
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  598 ERDAALQ----------------QLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVET 661
Cdd:TIGR00606  551 IRKIKSRhsdeltsllgyfpnkkQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFD 630
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  662 ACREQHE-------------AQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADA 728
Cdd:TIGR00606  631 VCGSQDEesdlerlkeeiekSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDK 710
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  729 LEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQAETEALRQE--LAEAIAAQRTAESECEQL 806
Cdd:TIGR00606  711 LKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQetLLGTIMPEEESAKVCLTD 790
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  807 VKEVAAWRERYEESQQEEAQYGAmfQEQLMTLKEECEKARQELQEAKEKVAGIESHSEL--QISRQQNELVElhaNLARA 884
Cdd:TIGR00606  791 VTIMERFQMELKDVERKIAQQAA--KLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELnrKLIQDQQEQIQ---HLKSK 865
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 1622865008  885 LQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQ 929
Cdd:TIGR00606  866 TNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQ 910
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
572-749 4.38e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 4.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  572 EKQEVTRRDHAQQLATAAEEREASLRER-DAALQQLEALEKEKaaKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQ 650
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKElEEAEAALEEFRQKN--GLVDLSEEAKLLLQQLSELESQLAEARAELAEAEA 240
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  651 KVEELRARVETACREQHEA---------QAQVAELEFQLQSEQQKATEKERVAQekdQLQEQLQALKESLKVTKGSLEEE 721
Cdd:COG3206    241 RLAALRAQLGSGPDALPELlqspviqqlRAQLAELEAELAELSARYTPNHPDVI---ALRAQIAALRAQLQQEAQRILAS 317
                          170       180
                   ....*....|....*....|....*...
gi 1622865008  722 KRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:COG3206    318 LEAELEALQAREASLQAQLAQLEARLAE 345
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
196-452 5.09e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 5.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  196 FLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL-ALLNEKQaasple 274
Cdd:COG4942      9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALeQELAALE------ 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  275 pRELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQE 354
Cdd:COG4942     83 -AELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  355 WLEKQAQLEKELSTALQDKKCLEEKNEILQGKLSQLEEHLALLREnppqekgevlgdvlQLETLKQEAATLAANNTQLQA 434
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEK--------------ELAELAAELAELQQEAEELEA 227
                          250
                   ....*....|....*...
gi 1622865008  435 RVETLETEQGQQEAKLLA 452
Cdd:COG4942    228 LIARLEAEAAAAAERTPA 245
PRK09039 PRK09039
peptidoglycan -binding protein;
556-692 6.41e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.19  E-value: 6.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  556 LSSSLKQKEQQLKEVAEK-QEVTR-----RDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANE 629
Cdd:PRK09039    44 LSREISGKDSALDRLNSQiAELADllsleRQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622865008  630 TRDSAQTSVTQAQREKAELSQKVEELR---ARVETAC----REQHEAQAQVAELEFQLQSE-QQKATEKER 692
Cdd:PRK09039   124 ELDSEKQVSARALAQVELLNQQIAALRrqlAALEAALdaseKRDRESQAKIADLGRRLNVAlAQRVQELNR 194
PRK11637 PRK11637
AmiB activator; Provisional
604-827 6.98e-04

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 44.30  E-value: 6.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  604 QQLEALEKEKAAKLEILQQQLQvaneTRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQlQSE 683
Cdd:PRK11637    47 DQLKSIQQDIAAKEKSVRQQQQ----QRASLLAQLKKQEEAISQASRKLRETQNTLNQLNKQIDELNASIAKLEQQ-QAA 121
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  684 QQKATEKE-----RVAQ----------EKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVE 748
Cdd:PRK11637   122 QERLLAAQldaafRQGEhtglqlilsgEESQRGERILAYFGYLNQARQETIAELKQTREELAAQKAELEEKQSQQKTLLY 201
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  749 QHKQEQKELEEEKAGRK----GLEARL----QQLGEAHQAETEaLRQELAEaiaAQRTAESECEQLVKEVAAWRERYEES 820
Cdd:PRK11637   202 EQQAQQQKLEQARNERKktltGLESSLqkdqQQLSELRANESR-LRDSIAR---AEREAKARAEREAREAARVRDKQKQA 277

                   ....*..
gi 1622865008  821 QQEEAQY 827
Cdd:PRK11637   278 KRKGSTY 284
PRK09039 PRK09039
peptidoglycan -binding protein;
1045-1201 7.24e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.19  E-value: 7.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1045 FATLQEALAHALTekeGKDQELVKLrgleAAQIKELEEL----RQTMKQLKEQLAKkekEHASGSGAQSEAAgrteptgp 1120
Cdd:PRK09039    37 FVVAQFFLSREIS---GKDSALDRL----NSQIAELADLlsleRQGNQDLQDSVAN---LRASLSAAEAERS-------- 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1121 KLEALRAEVSkleQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQ 1200
Cdd:PRK09039    99 RLQALLAELA---GAGAAAEGRAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRESQAKIA 175

                   .
gi 1622865008 1201 D 1201
Cdd:PRK09039   176 D 176
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1033-1599 7.91e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 7.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1033 RLQNALNEQRVEFATLQEALAH-----ALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKKEKEHASGSGA 1107
Cdd:COG4913    259 ELAERYAAARERLAELEYLRAAlrlwfAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGD 338
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1108 QseaagrteptgpkLEALRAEVskleqqcqqqqeqaDSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALAS 1187
Cdd:COG4913    339 R-------------LEQLEREI--------------ERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA 391
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1188 VQRELAALRTKVQDhskAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEkegeskelKRLVMAesEKSQKLED 1267
Cdd:COG4913    392 LLEALEEELEALEE---ALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLA--------LRDALA--EALGLDEA 458
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1268 RLR----LLQAETASNSAR-AAERssALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQA 1342
Cdd:COG4913    459 ELPfvgeLIEVRPEEERWRgAIER--VLGGFALTLLVPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSL 536
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1343 LSTLQLEHTSTQALVSELL--PAKHLCqqlqAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPL----RQKV 1416
Cdd:COG4913    537 AGKLDFKPHPFRAWLEAELgrRFDYVC----VDSPEELRRHPRAITRAGQVKGNGTRHEKDDRRRIRSRYVLgfdnRAKL 612
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1417 AEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLgrQFLEVELDQAREKYV---QELAAVRAD------A 1487
Cdd:COG4913    613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEY--SWDEIDVASAEREIAeleAELERLDASsddlaaL 690
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1488 ETRLAEVQREAQSTARELEVMTAKYEGAKvkvlEERQRFQEEKQKLTAQVEQLEvfQREQTKQVEELRKKLADSDQAsKV 1567
Cdd:COG4913    691 EEQLEELEAELEELEEELDELKGEIGRLE----KELEQAEEELDELQDRLEAAE--DLARLELRALLEERFAAALGD-AV 763
                          570       580       590
                   ....*....|....*....|....*....|..
gi 1622865008 1568 QQQKLKAVQAQGGESQQEAQRLQARLNELQAQ 1599
Cdd:COG4913    764 ERELRENLEERIDALRARLNRAEEELERAMRA 795
PRK11281 PRK11281
mechanosensitive channel MscK;
582-870 8.59e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.52  E-value: 8.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  582 AQQLATAAEEREASLRERDAALQQLEALEKEKAAKLE--ILQQQLQvanetrdSAQTSVTQAQREKAELsqkvEELRARV 659
Cdd:PRK11281    21 CLSSAFARAASNGDLPTEADVQAQLDALNKQKLLEAEdkLVQQDLE-------QTLALLDKIDRQKEET----EQLKQQL 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  660 ETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKE---------SLKVTKGSLEEekrRAADALE 730
Cdd:PRK11281    90 AQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLDQLQNaqndlaeynSQLVSLQTQPE---RAQAALY 166
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  731 EQQRCISELKAETRSLveqhkqeqkeleeeKAGRKGLEARLQQLGEAHQAETEAL----RQELAEAIAAQRTAESECEql 806
Cdd:PRK11281   167 ANSQRLQQIRNLLKGG--------------KVGGKALRPSQRVLLQAEQALLNAQndlqRKSLEGNTQLQDLLQKQRD-- 230
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622865008  807 vkEVAAWRERYEEsQQEEAQyGAMFQEQLmtlkEECEKARQELQEAKEKVAGIES---HSELQISRQ 870
Cdd:PRK11281   231 --YLTARIQRLEH-QLQLLQ-EAINSKRL----TLSEKTVQEAQSQDEAARIQANplvAQELEINLQ 289
mukB PRK04863
chromosome partition protein MukB;
300-555 8.64e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.56  E-value: 8.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  300 QDLKTEKSQMDRKISQLLEENGDLSF---KLREFASHLQQLQDALNELTEEHsratqeWLEKQAQLEKELSTALQDKKCL 376
Cdd:PRK04863   840 RQLNRRRVELERALADHESQEQQQRSqleQAKEGLSALNRLLPRLNLLADET------LADRVEEIREQLDEAEEAKRFV 913
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  377 EEKneilQGKLSQLEEHLALLRENPPQE---KGEVLGDVLQLETLKQEAATL----------------------AANNTQ 431
Cdd:PRK04863   914 QQH----GNALAQLEPIVSVLQSDPEQFeqlKQDYQQAQQTQRDAKQQAFALtevvqrrahfsyedaaemlaknSDLNEK 989
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  432 LQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSlianLQSSISNLSQAKEELEQASQAHGARLTA----QVASLTSEL 507
Cdd:PRK04863   990 LRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLAS----LKSSYDAKRQMLQELKQELQDLGVPADSgaeeRARARRDEL 1065
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622865008  508 TTLNATIQQQDQELadLKQQAKEEQAQLAQTLQ--QQEQASQGLRHQVEQ 555
Cdd:PRK04863  1066 HARLSANRSRRNQL--EKQLTFCEAEMDNLTKKlrKLERDYHEMREQVVN 1113
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1007-1488 9.29e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 9.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1007 ARLTQERGRAQADLALEKAAKAELEMRL-QNALNEQRVEFATLQEALAHALTEKEGKDQELVKLRG-LEAAQIKELEELR 1084
Cdd:COG4913    265 AAARERLAELEYLRAALRLWFAQRRLELlEAELEELRAELARLEAELERLEARLDALREELDELEAqIRGNGGDRLEQLE 344
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1085 QTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVskleqqcqqqQEQADSLERSLEAERASRAERDSAL 1164
Cdd:COG4913    345 REIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA----------AALLEALEEELEALEEALAEAEAAL 414
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1165 ETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKA--------------------------------------E 1206
Cdd:COG4913    415 RDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLdeaelpfvgelievrpeeerwrgaiervlggfaltllvP 494
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1207 DEWKAQVAR------------------GRQEAERKNSLISSLEEEVSI--------LNRQVLEKEG----ES-KELKRLV 1255
Cdd:COG4913    495 PEHYAAALRwvnrlhlrgrlvyervrtGLPDPERPRLDPDSLAGKLDFkphpfrawLEAELGRRFDyvcvDSpEELRRHP 574
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1256 MAESEKSQ-KLEDRLRLLQAETASNSA-----RAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQ-- 1327
Cdd:COG4913    575 RAITRAGQvKGNGTRHEKDDRRRIRSRyvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRla 654
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1328 -------ELKAWQEKFFQKEQALSTLQLEHTSTQALVSELlpakhlcqqlqAEQAAAEKRHREELEQSKQAAGGLRAELL 1400
Cdd:COG4913    655 eyswdeiDVASAEREIAELEAELERLDASSDDLAALEEQL-----------EELEAELEELEEELDELKGEIGRLEKELE 723
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1401 RAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLS-MLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQE 1479
Cdd:COG4913    724 QAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDaVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAE 803

                   ....*....
gi 1622865008 1480 LAAVRADAE 1488
Cdd:COG4913    804 TADLDADLE 812
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1412-1618 9.32e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 9.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1412 LRQKVAEQERTAQQLRAEKASYAEQL-------SMLKKAHGLLAEENRGLGERANLGRqfLEVELDQAREKYvQELAAVR 1484
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKELeeaeaalEEFRQKNGLVDLSEEAKLLLQQLSE--LESQLAEARAEL-AEAEARL 242
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1485 ADAETRLAEVQREAQSTAR--ELEVMTAKYEGAKVKVLEERQRFQEEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSD 1562
Cdd:COG3206    243 AALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAEL 322
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622865008 1563 QASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAK 1618
Cdd:COG3206    323 EALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
236-609 9.99e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.56  E-value: 9.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  236 ELAENRKLLTEKDAQIAMMQQRIDRLAL---------LNEKQAASPLEprELEELRDKNESLTMRLHETLKQCQDLKTEK 306
Cdd:COG3096    789 ELRAERDELAEQYAKASFDVQKLQRLHQafsqfvgghLAVAFAPDPEA--ELAALRQRRSELERELAQHRAQEQQLRQQL 866
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  307 SQMDRKISQL--------LEENGDLSFKLREFASHLQQLQDALNELTEEHSRAtqewlekqAQLEKELSTALQDKkcleE 378
Cdd:COG3096    867 DQLKEQLQLLnkllpqanLLADETLADRLEELREELDAAQEAQAFIQQHGKAL--------AQLEPLVAVLQSDP----E 934
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  379 KNEILQGKLSQLEEHLALLrenppQEKGEVLGDVLQLET---LKQEAATLAAN---NTQLQARVETLETEQGQQEAKLLA 452
Cdd:COG3096    935 QFEQLQADYLQAKEQQRRL-----KQQIFALSEVVQRRPhfsYEDAVGLLGENsdlNEKLRARLEQAEEARREAREQLRQ 1009
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  453 ERDHFEEEKQQLSSLIANLQSSISNLSQAKEEL-----------EQASQAHGARLTAQVASLTSELTTLNATIQQQDQEL 521
Cdd:COG3096   1010 AQAQYSQYNQVLASLKSSRDAKQQTLQELEQELeelgvqadaeaEERARIRRDELHEELSQNRSRRSQLEKQLTRCEAEM 1089
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  522 ADLKQQAKEEQAQLaqtlqqqeqasQGLRHQVEQlsssLKQKEQQLKEVAEKQEVTRRDHAQQLA-TAAEEREASLRERD 600
Cdd:COG3096   1090 DSLQKRLRKAERDY-----------KQEREQVVQ----AKAGWCAVLRLARDNDVERRLHRRELAyLSADELRSMSDKAL 1154

                   ....*....
gi 1622865008  601 AALQQLEAL 609
Cdd:COG3096   1155 GALRLAVAD 1163
46 PHA02562
endonuclease subunit; Provisional
307-527 1.02e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  307 SQMDR----KISQLLEENGDLSFKLRefasHLQQLQDALNELTEEHSRATQEWL-EKQAQLEKELSTALQDKKCLEEKNE 381
Cdd:PHA02562   166 SEMDKlnkdKIRELNQQIQTLDMKID----HIQQQIKTYNKNIEEQRKKNGENIaRKQNKYDELVEEAKTIKAEIEELTD 241
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  382 ILQGKLSQLE---EHLALLRENPPQEKGEV--LGDVLQLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDH 456
Cdd:PHA02562   242 ELLNLVMDIEdpsAALNKLNTAAAKIKSKIeqFQKVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTA 321
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  457 FEEEKQ------QLSSLIANLQSSISNLSQA-KEELEQASQAHGA--RLTAQVASLTSELTTLNATIQQQDQELADLKQQ 527
Cdd:PHA02562   322 IDELEEimdefnEQSKKLLELKNKISTNKQSlITLVDKAKKVKAAieELQAEFVDNAEELAKLQDELDKIVKTKSELVKE 401
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
561-789 1.09e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.96  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  561 KQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKL-EILQQQLQVANETRDSAQTSVT 639
Cdd:pfam17380  359 KRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIqQQKVEMEQIRAEQEEARQREVR 438
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  640 QAQREKAELSQKV--EELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGS 717
Cdd:pfam17380  439 RLEEERAREMERVrlEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLL 518
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622865008  718 LEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQ-AETEALRQEL 789
Cdd:pfam17380  519 EKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQiVESEKARAEY 591
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1395-1741 1.21e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1395 LRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRqfLEVELDQARE 1474
Cdd:COG4717     76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAE--LPERLEELEE 153
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1475 KYvQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEEKQKLTAQVEQLEVFQREQTKQVEEL 1554
Cdd:COG4717    154 RL-EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1555 RKKLADSDQASKVQQQKL--------------------------KAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAE 1608
Cdd:COG4717    233 ENELEAAALEERLKEARLllliaaallallglggsllsliltiaGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPA 312
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1609 HYKLQMEKAKTHYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQAGLKTKEAEqtcrhltaqvrSLEAQVA 1688
Cdd:COG4717    313 LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAA-----------LLAEAGV 381
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622865008 1689 HADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSKL 1741
Cdd:COG4717    382 EDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEEL 434
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
603-708 1.27e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 43.56  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  603 LQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVEtacreqHEAQAQVAELEFQLQS 682
Cdd:TIGR04320  256 LAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQAL------QTAQNNLATAQAALAN 329
                           90       100
                   ....*....|....*....|....*..
gi 1622865008  683 -EQQKATEKERVAQEKDQLQEQLQALK 708
Cdd:TIGR04320  330 aEARLAKAKEALANLNADLAKKQAALD 356
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
209-788 1.31e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  209 LQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLAllneKQAASPLEPRELE--------- 279
Cdd:TIGR00618  281 ETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHV----KQQSSIEEQRRLLqtlhsqeih 356
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  280 ------------ELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEE 347
Cdd:TIGR00618  357 irdahevatsirEISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQ 436
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  348 HSRATQEWL--EKQAQLEKELSTALQD--------KKCLEEKNEILQGKLSQLEEHLALLRENPPQEKgEVLGDVLQLET 417
Cdd:TIGR00618  437 QRYAELCAAaiTCTAQCEKLEKIHLQEsaqslkerEQQLQTKEQIHLQETRKKAVVLARLLELQEEPC-PLCGSCIHPNP 515
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  418 LKQEAATLAANNTQLQA---RVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEqasqahga 494
Cdd:TIGR00618  516 ARQDIDNPGPLTRRMQRgeqTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIP-------- 587
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  495 rltaqvaSLTSELTTLNATIQQQDqELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVA-EK 573
Cdd:TIGR00618  588 -------NLQNITVRLQDLTEKLS-EAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTqER 659
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  574 QEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVA-------NETRDSAQTSVTQAQREKA 646
Cdd:TIGR00618  660 VREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIeeydrefNEIENASSSLGSDLAARED 739
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  647 ELSQKVEELRARVETACREQHEAQAQVAElefQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAA 726
Cdd:TIGR00618  740 ALNQSLKELMHQARTVLKARTEAHFNNNE---EVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDE 816
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622865008  727 DALEEQQRCISELKAETRSLVEQHKQEQKELEEEKagrKGLEARLQQLGEAHQAETEALRQE 788
Cdd:TIGR00618  817 DILNLQCETLVQEEEQFLSRLEEKSATLGEITHQL---LKYEECSKQLAQLTQEQAKIIQLS 875
COG4995 COG4995
Uncharacterized conserved protein, contains CHAT domain [Function unknown];
510-947 1.33e-03

Uncharacterized conserved protein, contains CHAT domain [Function unknown];


Pssm-ID: 444019 [Multi-domain]  Cd Length: 711  Bit Score: 43.80  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  510 LNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAA 589
Cdd:COG4995      2 LALALLALLAALLAALALALLALALLLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALA 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  590 EEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEA 669
Cdd:COG4995     82 LAALALALLAAALALALAAAALAALALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAAAAAA 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  670 QAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:COG4995    162 AAALLALALALAAAALALLALLLAALAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALL 241
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  750 HKQEQKELEEEKAGRKGLEARLQQLGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGA 829
Cdd:COG4995    242 ALAAAAAALAAAAAALLALAAALLLLAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALALLLLA 321
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  830 MFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQN-----ELVELHANLARALQQVQEKEVRAQKLADDLST 904
Cdd:COG4995    322 ALLLLLAALALLALLLLLAAAALLAAALAAALALAAALALALLaalllLLAALLALLLEALLLLLLALLAALLLLAAALL 401
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1622865008  905 LQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDR 947
Cdd:COG4995    402 ALAAAQLLRLLLAALALLLALAAYAAARLALLALIEYIILPDR 444
PRK09039 PRK09039
peptidoglycan -binding protein;
496-660 1.40e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.03  E-value: 1.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  496 LTAQVASLTSELTTLNATIQQQDQELAdLKQQAKeeqaqlaqtlqqqeqasQGLRHQVEQLSSSLKQKEqqlkevAEKQE 575
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLLS-LERQGN-----------------QDLQDSVANLRASLSAAE------AERSR 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  576 V-TRRDHAQQLATAAEEREASLrerDAALQQLEALEKEKAAKLEILQQQLQV-------------ANETRDSAQTSVTQA 641
Cdd:PRK09039   100 LqALLAELAGAGAAAEGRAGEL---AQELDSEKQVSARALAQVELLNQQIAAlrrqlaaleaaldASEKRDRESQAKIAD 176
                          170       180
                   ....*....|....*....|..
gi 1622865008  642 --QREKAELSQKVEEL-RARVE 660
Cdd:PRK09039   177 lgRRLNVALAQRVQELnRYRSE 198
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1144-1331 1.55e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1144 DSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVAR-------- 1215
Cdd:COG4942     37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEllralyrl 116
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1216 GRQ-------------EAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSAR 1282
Cdd:COG4942    117 GRQpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAE 196
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1622865008 1283 AAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKA 1331
Cdd:COG4942    197 RQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
mukB PRK04863
chromosome partition protein MukB;
224-711 1.57e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 1.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  224 ADERSNRDELELELaenRKLLTEKDAQIAMMQQRIDRLAllnekqaasplepRELEELRDkNESLTMRLHETLKQCQDLK 303
Cdd:PRK04863   278 ANERRVHLEEALEL---RRELYTSRRQLAAEQYRLVEMA-------------RELAELNE-AESDLEQDYQAASDHLNLV 340
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  304 TEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEWLEKQAQLeKELSTALqdkkcleeknEIL 383
Cdd:PRK04863   341 QTALRQQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQL-ADYQQAL----------DVQ 409
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  384 QGKLSQLEEHLALLREnppqEKGEVLGDVLQLETLKQEAATLAANNTQLQARVetLETEQGQQEAKllAERDHFEEEKQQ 463
Cdd:PRK04863   410 QTRAIQYQQAVQALER----AKQLCGLPDLTADNAEDWLEEFQAKEQEATEEL--LSLEQKLSVAQ--AAHSQFEQAYQL 481
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  464 LSSLIANLQSSISNlSQAKEELEQASqahgarltaqvasltsELTTLNATIQQQDQELADLKQQAKEEQAQlaqtlqqqe 543
Cdd:PRK04863   482 VRKIAGEVSRSEAW-DVARELLRRLR----------------EQRHLAEQLQQLRMRLSELEQRLRQQQRA--------- 535
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  544 qasQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREAsLRerdaalQQLEALeKEKAAKLEILQQQ 623
Cdd:PRK04863   536 ---ERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMA-LR------QQLEQL-QARIQRLAARAPA 604
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  624 LQVANE--TRDSAQTSVTQAQrekaelSQKVEELRARVETACREQHEAQAQVAELEFQLQSeqqkatEKERVAQEKDQLQ 701
Cdd:PRK04863   605 WLAAQDalARLREQSGEEFED------SQDVTEYMQQLLERERELTVERDELAARKQALDE------EIERLSQPGGSED 672
                          490
                   ....*....|
gi 1622865008  702 EQLQALKESL 711
Cdd:PRK04863   673 PRLNALAERF 682
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
700-1178 1.60e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  700 LQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQ 779
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  780 AetEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGI 859
Cdd:COG4717    127 L--LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  860 EShselQISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAAtskeVARLETLVRKAGEQQETASRELVK 939
Cdd:COG4717    205 QQ----RLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLL----LIAAALLALLGLGGSLLSLILTIA 276
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  940 EPARAGDREPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLtqergrAQAD 1019
Cdd:COG4717    277 GVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRI------EELQ 350
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1020 LALEKAAKAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQTMKQLKEQLAKK-- 1097
Cdd:COG4717    351 ELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEel 430
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1098 EKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADslERSLEAERASRAERDSALETLQGQLEEKARE 1177
Cdd:COG4717    431 EEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQE--LEELKAELRELAEEWAALKLALELLEEAREE 508

                   .
gi 1622865008 1178 L 1178
Cdd:COG4717    509 Y 509
PRK09039 PRK09039
peptidoglycan -binding protein;
866-988 1.74e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.03  E-value: 1.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  866 QISRQQNELVELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETL-VRKAGEQQETASRELVKEPARA 944
Cdd:PRK09039    47 EISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALlAELAGAGAAAEGRAGELAQELD 126
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622865008  945 --------GDREPEWLEEQQG---RQFCSTQAALQAMEREAEQMGNELE----RLRAAL 988
Cdd:PRK09039   127 sekqvsarALAQVELLNQQIAalrRQLAALEAALDASEKRDRESQAKIAdlgrRLNVAL 185
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
1170-1346 1.81e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 43.50  E-value: 1.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1170 QLEEKARELGHSQSALASVQ----RELAALRTKVQDHSKAED-EWKAQVARGRQEAERKNSLISSLE-EEVSILNRQvle 1243
Cdd:PRK10929   127 QEQDRAREISDSLSQLPQQQtearRQLNEIERRLQTLGTPNTpLAQAQLTALQAESAALKALVDELElAQLSANNRQ--- 203
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1244 kegeskELKRLvmaESEKSQKLEDRLRLLQAETASN--------SARAAERSSALREEVQSLREEAEKQRVASENLRQEL 1315
Cdd:PRK10929   204 ------ELARL---RSELAKKRSQQLDAYLQALRNQlnsqrqreAERALESTELLAEQSGDLPKSIVAQFKINRELSQAL 274
                          170       180       190
                   ....*....|....*....|....*....|.
gi 1622865008 1316 TSQAERAEELGQELKAWQEKFFQKEQALSTL 1346
Cdd:PRK10929   275 NQQAQRMDLIASQQRQAASQTLQVRQALNTL 305
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
326-486 1.86e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 1.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  326 KLREFASHLQQLQDALNELTEEHSRATQEWLEKQAQLeKELSTALQDKKCLEEKNEILQGKLSQLEEHLALLREnppqek 405
Cdd:COG1579     25 RLKELPAELAELEDELAALEARLEAAKTELEDLEKEI-KRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQKE------ 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  406 gevlgdvlqLETLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEEL 485
Cdd:COG1579     98 ---------IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168

                   .
gi 1622865008  486 E 486
Cdd:COG1579    169 A 169
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
284-683 1.89e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 43.13  E-value: 1.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  284 KNESLTMRLHETLKQCQDLKTEKSQmdrkISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEwlekQAQLE 363
Cdd:pfam19220    4 RNELLRVRLGEMADRLEDLRSLKAD----FSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRE----LAGLT 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  364 KELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQ 443
Cdd:pfam19220   76 RRLSAAEGELEELVARLAKLEAALREAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKALREEAQAAEKAL 155
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  444 GQQEAKLLAERDH---FEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQE 520
Cdd:pfam19220  156 QRAEGELATARERlalLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEGQLAAEQAERERAEAQLEEA 235
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  521 LADLKqqakeeqaqlaqtlqqqeQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQevtrRDHAQQLATAAEEREASLRERD 600
Cdd:pfam19220  236 VEAHR------------------AERASLRMKLEALTARAAATEQLLAEARNQL----RDRDEAIRAAERRLKEASIERD 293
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  601 AALQQLEALEKEKAAKLEILQQQLQVANETRDSA----------QTSVTQAQREKAELSQKVEELRARVETacrEQHEAQ 670
Cdd:pfam19220  294 TLERRLAGLEADLERRTQQFQEMQRARAELEERAemltkalaakDAALERAEERIASLSDRIAELTKRFEV---ERAALE 370
                          410
                   ....*....|...
gi 1622865008  671 AQVAELEFQLQSE 683
Cdd:pfam19220  371 QANRRLKEELQRE 383
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
1144-1270 2.15e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 2.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1144 DSLERSLEAERAsraERDSALETLQGQLEEKARELghsQSALASVQRELAALRTKVQdhskAEDEWKAQVARGRQEAERK 1223
Cdd:COG0542    414 DELERRLEQLEI---EKEALKKEQDEASFERLAEL---RDELAELEEELEALKARWE----AEKELIEEIQELKEELEQR 483
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622865008 1224 NSLISSLEEEVSILNRQVLEKEGESKE------------------LKRLVMAESEKSQKLEDRLR 1270
Cdd:COG0542    484 YGKIPELEKELAELEEELAELAPLLREevteediaevvsrwtgipVGKLLEGEREKLLNLEEELH 548
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1471-1693 2.29e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1471 QAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEEKQKLTAQVEQLEVFQREQTKQ 1550
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1551 VEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQE 1630
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622865008 1631 LQEQLQSLEHLQKENKELRAEAERLGHELQQAGLKTKEAEQTcrhLTAQVRSLEAQVAHADQQ 1693
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE---LEALIARLEAEAAAAAER 242
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
572-741 2.31e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 42.49  E-value: 2.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  572 EKQEVTRRDHAQQLATAAEEREASLRERDAALQQ-LEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQ 650
Cdd:PRK09510    68 QQQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQErLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAAAKA 147
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  651 KVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKvtKGSLEEEKRRAADALE 730
Cdd:PRK09510   148 KAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKK--KAAAEAKKKAAAEAKA 225
                          170
                   ....*....|.
gi 1622865008  731 EQQRCISELKA 741
Cdd:PRK09510   226 AAAKAAAEAKA 236
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
553-748 2.42e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 42.68  E-value: 2.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  553 VEQLSSSLKQKEQQLKEVAEKQEVTRRDhaqqlATAAEEREASLRERDAalQQLEALEKEKAAKLEILQQQLQVANETRD 632
Cdd:pfam05262  172 VDTDSISDKKVVEALREDNEKGVNFRRD-----MTDLKERESQEDAKRA--QQLKEELDKKQIDADKAQQKADFAQDNAD 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  633 SAQTSVTQAQREKAELSQKveelrARVETACREQHEAQAQVAELEfQLQSEQQKATEKERVAqeKDQLQEQL-QALKESL 711
Cdd:pfam05262  245 KQRDEVRQKQQEAKNLPKP-----ADTSSPKEDKQVAENQKREIE-KAQIEIKKNDEEALKA--KDHKAFDLkQESKASE 316
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1622865008  712 KVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVE 748
Cdd:pfam05262  317 KEAEDKELEAQKKREPVAEDLQKTKPQVEAQPTSLNE 353
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
518-657 2.46e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 42.34  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  518 DQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLkEVAEKQEVTRRDHAQQLATAAEEREASLR 597
Cdd:COG1566     77 DPTDLQAALAQAEAQLAAAEAQLARLEAELGAEAEIAAAEAQLAAAQAQL-DLAQRELERYQALYKKGAVSQQELDEARA 155
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622865008  598 ERDAALQQLEALEkekaAKLEILQQQLQVANETRDS-AQTSVTQAQREKAELSQKVEELRA 657
Cdd:COG1566    156 ALDAAQAQLEAAQ----AQLAQAQAGLREEEELAAAqAQVAQAEAALAQAELNLARTTIRA 212
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
358-749 2.83e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.89  E-value: 2.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  358 KQAQLEKELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENppqekgevlgdvlqLETLKQEAATLAANNTQLQARVE 437
Cdd:pfam10174  290 KIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKES--------------LTAKEQRAAILQTEVDALRLRLE 355
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  438 TLETEQGQQEAKLLaerdHFEEEKQQLSSLIAN--------------LQSSISNLS-QAKEELEQASQAHGARLTAQVAS 502
Cdd:pfam10174  356 EKESFLNKKTKQLQ----DLTEEKSTLAGEIRDlkdmldvkerkinvLQKKIENLQeQLRDKDKQLAGLKERVKSLQTDS 431
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  503 LTSE--LTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEkqevtrrd 580
Cdd:pfam10174  432 SNTDtaLTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKE-------- 503
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  581 HAQQLATAAEEREASLRERDAALQQ------------LEALEKEKAA--------KLEILQQQLQVANETRDSAQTSV-- 638
Cdd:pfam10174  504 HASSLASSGLKKDSKLKSLEIAVEQkkeecsklenqlKKAHNAEEAVrtnpeindRIRLLEQEVARYKEESGKAQAEVer 583
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  639 -----TQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQE---KDQLQEQLQALKES 710
Cdd:pfam10174  584 llgilREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDnlaDNSQQLQLEELMGA 663
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 1622865008  711 LKVTKGSLEEEKRRAAD---ALEEQQRCISELKAETRSLVEQ 749
Cdd:pfam10174  664 LEKTRQELDATKARLSStqqSLAEKDGHLTNLRAERRKQLEE 705
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1151-1361 2.96e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 2.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1151 EAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEdewkaQVARGRQEAERKNSLISSL 1230
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQ-----QLSELESQLAEARAELAEA 238
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1231 EEEVSILNRQVLEKEGESKELkrlvmAESEKSQKLEDRLRLLQAETASNSARAAERSS---ALREEVQSLR----EEAEK 1303
Cdd:COG3206    239 EARLAALRAQLGSGPDALPEL-----LQSPVIQQLRAQLAELEAELAELSARYTPNHPdviALRAQIAALRaqlqQEAQR 313
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622865008 1304 QRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELL 1361
Cdd:COG3206    314 ILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLL 371
mukB PRK04863
chromosome partition protein MukB;
340-983 2.98e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  340 ALNELTEEHSRATQEWLEKQAQLEKELSTALQDKKCLEEKNE---ILQGKLSQLEEHLALLRENppqekgevlgdVLQLE 416
Cdd:PRK04863   280 ERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEaesDLEQDYQAASDHLNLVQTA-----------LRQQE 348
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  417 TLKQEAATLAANNTQLQARVETLETEQGQQEAkLLAERDHFEEEKQQLSSLIANLQSSI-------SNLSQAKEELEQAS 489
Cdd:PRK04863   349 KIERYQADLEELEERLEEQNEVVEEADEQQEE-NEARAEAAEEEVDELKSQLADYQQALdvqqtraIQYQQAVQALERAK 427
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  490 QAHG-ARLTAqvASLTSELTTLNATIQQQDQELADLKQQ------AKE----------------EQAQLAQTLQQQEQAS 546
Cdd:PRK04863   428 QLCGlPDLTA--DNAEDWLEEFQAKEQEATEELLSLEQKlsvaqaAHSqfeqayqlvrkiagevSRSEAWDVARELLRRL 505
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  547 QGLRHQVEQLSsslkQKEQQLKEVaeKQEVTRRDHAQQLATAAEEReASLRERDAAlqQLEALEKEKAAKLEILQQQLQV 626
Cdd:PRK04863   506 REQRHLAEQLQ----QLRMRLSEL--EQRLRQQQRAERLLAEFCKR-LGKNLDDED--ELEQLQEELEARLESLSESVSE 576
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  627 ANETRDSAQTSVTQAQREKAELSQKVEELRA------RVETACREQHEAQAQVAELEFQLQSEQQKAT-EKERVAQEKDQ 699
Cdd:PRK04863   577 ARERRMALRQQLEQLQARIQRLAARAPAWLAaqdalaRLREQSGEEFEDSQDVTEYMQQLLERERELTvERDELAARKQA 656
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  700 LQEQ--------------LQALKESLK---VTKG----SLEE------------------EKRRAADALEEQQRC----- 735
Cdd:PRK04863   657 LDEEierlsqpggsedprLNALAERFGgvlLSEIyddvSLEDapyfsalygparhaivvpDLSDAAEQLAGLEDCpedly 736
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  736 ---------------------------------------------------ISELKAETRSLVEQHKQEQKELEEEKAGR 764
Cdd:PRK04863   737 liegdpdsfddsvfsveelekavvvkiadrqwrysrfpevplfgraarekrIEQLRAEREELAERYATLSFDVQKLQRLH 816
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  765 KGLEARL-QQLGEAHQAETEA----LRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAMFQEqlmTLK 839
Cdd:PRK04863   817 QAFSRFIgSHLAVAFEADPEAelrqLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLNLLADE---TLA 893
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  840 EECEKARQELQEAKEKVAGIESHSEL--QISRQQNEL---VELHANLARALQQVQEKEVRAQKLADDLSTL--------- 905
Cdd:PRK04863   894 DRVEEIREQLDEAEEAKRFVQQHGNAlaQLEPIVSVLqsdPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVvqrrahfsy 973
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  906 ---QEKMAATSKEVARLETLVRKAgEQQETASRELVKEparagdrepewlEEQQGRQFCSTQAALQAMEREAEQMGNELE 982
Cdd:PRK04863   974 edaAEMLAKNSDLNEKLRQRLEQA-EQERTRAREQLRQ------------AQAQLAQYNQVLASLKSSYDAKRQMLQELK 1040

                   .
gi 1622865008  983 R 983
Cdd:PRK04863  1041 Q 1041
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
554-903 2.98e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  554 EQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAA---KLEILQQQLQVANET 630
Cdd:COG4372      2 DRLGEKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQleeELEQARSELEQLEEE 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  631 RDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKES 710
Cdd:COG4372     82 LEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLES 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  711 LKVTKGSLEEEKRRAADALEEQQrcISELKAETRSLVEQHKQEQKELEEEKAGRKGLEARLQqlgeahQAETEALRQELA 790
Cdd:COG4372    162 LQEELAALEQELQALSEAEAEQA--LDELLKEANRNAEKEEELAEAEKLIESLPRELAEELL------EAKDSLEAKLGL 233
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  791 EAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQ 870
Cdd:COG4372    234 ALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGAL 313
                          330       340       350
                   ....*....|....*....|....*....|...
gi 1622865008  871 QNELVELHANLARALQQVQEKEVRAQKLADDLS 903
Cdd:COG4372    314 EDALLAALLELAKKLELALAILLAELADLLQLL 346
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1569-1697 2.99e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.96  E-value: 2.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1569 QQKLKAVQAQGGESQQEAQRLQARLnELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLQSLEHLQKENKEL 1648
Cdd:COG1566     82 QAALAQAEAQLAAAEAQLARLEAEL-GAEAEIAAAEAQLAAAQAQLDLAQRELERYQALYKKGAVSQQELDEARAALDAA 160
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1622865008 1649 RAEAERLGHELQQAGLKTKEAEQTcRHLTAQVRSLEAQVAHADQQLRDL 1697
Cdd:COG1566    161 QAQLEAAQAQLAQAQAGLREEEEL-AAAQAQVAQAEAALAQAELNLART 208
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
476-699 3.14e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  476 SNLSQAKEELEQAsQAHGARLTAQVASLTSELTTLNATIQQQDQELADLKQQAKEeqaqlaqtlqqqeqasqgLRHQVEQ 555
Cdd:COG3883     16 PQIQAKQKELSEL-QAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDK------------------LQAEIAE 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  556 LSSSLKQKEQQLKEVAEKQEVTRR------------------DHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKL 617
Cdd:COG3883     77 AEAEIEERREELGERARALYRSGGsvsyldvllgsesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKL 156
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  618 EILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEK 697
Cdd:COG3883    157 AELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236

                   ..
gi 1622865008  698 DQ 699
Cdd:COG3883    237 AA 238
COG5283 COG5283
Phage-related tail protein [Mobilome: prophages, transposons];
1589-1710 3.17e-03

Phage-related tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444094 [Multi-domain]  Cd Length: 747  Bit Score: 42.53  E-value: 3.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1589 LQARLNELQAQLSQKEQAAEHYKLQMEKAKThydAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQAGLKTKE 1668
Cdd:COG5283      5 LGAVDKPFKSALESAKQRVAALAQALKALEA---PTRALARALERAKQAAARLQTKYNKLRQSLQRLRQALDQAGIDTRQ 81
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 1622865008 1669 AEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSR 1710
Cdd:COG5283     82 LSAAQRRLRSSLEQTNRQLERQQQRLARLGARQDRLKAARAR 123
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
508-860 3.17e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.57  E-value: 3.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  508 TTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLAT 587
Cdd:pfam07888   30 ELLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSAS 109
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  588 A---AEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACR 664
Cdd:pfam07888  110 SeelSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRS 189
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  665 EQHEAQ----------AQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQR 734
Cdd:pfam07888  190 LSKEFQelrnslaqrdTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDR 269
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  735 CISEL---KAETRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVA 811
Cdd:pfam07888  270 TQAELhqaRLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELG 349
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1622865008  812 AWRERYEESQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIE 860
Cdd:pfam07888  350 REKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLE 398
COG5022 COG5022
Myosin heavy chain [General function prediction only];
235-569 3.40e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 42.76  E-value: 3.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  235 LELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQ--------------AASPLEPRE-LEELRDKNESL--TMRLHETLK 297
Cdd:COG5022    803 LSLLGSRKEYRSYLACIIKLQKTIKREKKLRETEevefslkaevliqkFGRSLKAKKrFSLLKKETIYLqsAQRVELAER 882
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  298 QCQDLKTEksqmDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHS---------RATQEWLEKQAQLEKELST 368
Cdd:COG5022    883 QLQELKID----VKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIarlkkllnnIDLEEGPSIEYVKLPELNK 958
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  369 ALQDKKCLEEKNEILQGKLSQLEEHlallrenppqeKGEVLGDVLQLETLKQEAATLAANNTQLQARVETLETEQG---- 444
Cdd:COG5022    959 LHEVESKLKETSEEYEDLLKKSTIL-----------VREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVevae 1027
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  445 -QQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQA--SQAHGARLTAQVASLTSELTTLNAT-IQQQDQE 520
Cdd:COG5022   1028 lQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRreNSLLDDKQLYQLESTENLLKTINVKdLEVTNRN 1107
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1622865008  521 LadLKQQAKEEQAQLAQTLQQQEQASQGLrhqVEQLSSSLKQKEQQLKE 569
Cdd:COG5022   1108 L--VKPANVLQFIVAQMIKLNLLQEISKF---LSQLVNTLEPVFQKLSV 1151
Rab5-bind pfam09311
Rabaptin-like protein; Members of this family are predominantly found in Rabaptin and allow ...
297-580 3.47e-03

Rabaptin-like protein; Members of this family are predominantly found in Rabaptin and allow for binding to the GTPase Rab5. This interaction is necessary and sufficient for Rab5-dependent recruitment of Rabaptin5 to early endosomal membranes.


Pssm-ID: 462752 [Multi-domain]  Cd Length: 307  Bit Score: 41.88  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  297 KQCQDLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQEWLEKQAQLEKELSTAL----QD 372
Cdd:pfam09311    9 KQLQAIQEQEAETRDQVKKLQEMLRQANDQLEKTMKDKKELEDKMNQLSEETSNQVSTLAKRNQKSETLLDELQqafsQA 88
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  373 KKCLEEKNEILQGKLSQLEEHLALLRENPPQEKGEvlgDVLQLETLKQEAATLAANNTQLQARVETLETEqgqqeakLLA 452
Cdd:pfam09311   89 KRNFQDQLAVLMDSREQVSDELVRLQKDNESLQGK---HSLHVSLQQAEKFDMPDTVQELQELVLKYREE-------LIE 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  453 ERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELADLKQQAK--E 530
Cdd:pfam09311  159 VRTAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQAEIENCKEEIASISSLKVELERIKAEKEQLENGLTEKIRqlE 238
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622865008  531 EQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRD 580
Cdd:pfam09311  239 DLQTTKGSLETQLKKETNEKAAVEQLVFEEKNKAQRLQTELDVSEQVQRD 288
PRK13729 PRK13729
conjugal transfer pilus assembly protein TraB; Provisional
634-716 3.65e-03

conjugal transfer pilus assembly protein TraB; Provisional


Pssm-ID: 184281 [Multi-domain]  Cd Length: 475  Bit Score: 42.12  E-value: 3.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  634 AQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEfqlqseqqkatekervaQEKDQLQEQLQALKESLKV 713
Cdd:PRK13729    67 RQHATTEMQVTAAQMQKQYEEIRRELDVLNKQRGDDQRRIEKLG-----------------QDNAALAEQVKALGANPVT 129

                   ...
gi 1622865008  714 TKG 716
Cdd:PRK13729   130 ATG 132
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
1078-1347 3.71e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 41.98  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1078 KELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEptgpKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASR 1157
Cdd:pfam19220   38 AILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTR----RLSAAEGELEELVARLAKLEAALREAEAAKEELRIEL 113
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1158 AERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSIL 1237
Cdd:pfam19220  114 RDKTAQAEALERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQALSEEQAAELAEL 193
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1238 NRQVLEKEGESK-ELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSA-----------------LREEVQSLRE 1299
Cdd:pfam19220  194 TRRLAELETQLDaTRARLRALEGQLAAEQAERERAEAQLEEAVEAHRAERASLrmklealtaraaateqlLAEARNQLRD 273
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622865008 1300 EAEKQRVASENLRQ---ELTSQAERAEELGQELKAWQEKFFQKEQALSTLQ 1347
Cdd:pfam19220  274 RDEAIRAAERRLKEasiERDTLERRLAGLEADLERRTQQFQEMQRARAELE 324
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1148-1699 3.73e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 3.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1148 RSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHskaeDEWKAQVARGRQEAERKNSLI 1227
Cdd:PRK03918   179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL----EELKEEIEELEKELESLEGSK 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1228 SSLEEEVSILNRQVLEKEGESKELKRLV--MAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEkqr 1305
Cdd:PRK03918   255 RKLEEKIRELEERIEELKKEIEELEEKVkeLKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK--- 331
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1306 vasenlrqELTSQAERAEELGQELKAWQEKFFQKEQALSTLQlehtstqalvsellpakhlcqqlqaeqaaAEKRHREEL 1385
Cdd:PRK03918   332 --------ELEEKEERLEELKKKLKELEKRLEELEERHELYE-----------------------------EAKAKKEEL 374
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1386 EQSKQAAGGLRAEllRAQRELGELIPLRQKVAEQERTaqqLRAEKASYAEQLSMLKKAhglLAEENRGLGERANLGRQFL 1465
Cdd:PRK03918   375 ERLKKRLTGLTPE--KLEKELEELEKAKEEIEEEISK---ITARIGELKKEIKELKKA---IEELKKAKGKCPVCGRELT 446
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1466 EVELDQAREKYVQELAAVRADAEtRLAEVQREAQSTARELEVMTAKYEGAKV--KVLEERQRFQEEKQKLtaQVEQLEVF 1543
Cdd:PRK03918   447 EEHRKELLEEYTAELKRIEKELK-EIEEKERKLRKELRELEKVLKKESELIKlkELAEQLKELEEKLKKY--NLEELEKK 523
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1544 QREQTKQVEELRK------KLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQaqLSQKEQAAEHYKlQMEKA 1617
Cdd:PRK03918   524 AEEYEKLKEKLIKlkgeikSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELG--FESVEELEERLK-ELEPF 600
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1618 KTHYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQA-----GLKTKEAEQTCRHLTAQVRSLEAQVAHADQ 1692
Cdd:PRK03918   601 YNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELrkeleELEKKYSEEEYEELREEYLELSRELAGLRA 680

                   ....*..
gi 1622865008 1693 QLRDLGK 1699
Cdd:PRK03918   681 ELEELEK 687
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
552-745 3.86e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  552 QVEQLSSSLKQKEQQLKEVAEKQEVTrrdhAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETR 631
Cdd:COG3883     24 ELSELQAELEAAQAELDALQAELEEL----NEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSG 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  632 DSA--------QTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQ 703
Cdd:COG3883    100 GSVsyldvllgSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAE 179
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1622865008  704 LQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRS 745
Cdd:COG3883    180 QEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
396-562 3.90e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 41.64  E-value: 3.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  396 LLRENPPQEKGEVLgdvLQLE--TLKQEAATLAANNTQLQARVETLETEQGQQEAKLLAErdhfEEEKQQLSSLIANLQS 473
Cdd:pfam00529   35 LVKEGDRVKAGDVL---FQLDptDYQAALDSAEAQLAKAQAQVARLQAELDRLQALESEL----AISRQDYDGATAQLRA 107
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  474 SISNLSQAKEELEQA-SQAHGARLTAQV------------ASLTSELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQ 540
Cdd:pfam00529  108 AQAAVKAAQAQLAQAqIDLARRRVLAPIggisreslvtagALVAQAQANLLATVAQLDQIYVQITQSAAENQAEVRSELS 187
                          170       180
                   ....*....|....*....|..
gi 1622865008  541 QQEQASQGLRHQVEQLSSSLKQ 562
Cdd:pfam00529  188 GAQLQIAEAEAELKLAKLDLER 209
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
282-531 3.93e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 3.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  282 RDKNESLTmRLHET-LKQCQDLKTEKSQMdrKISQLLEENGDLSF---KLREFASHLQQLQDALNELTEehsratQEWLE 357
Cdd:PRK05771    16 SYKDEVLE-ALHELgVVHIEDLKEELSNE--RLRKLRSLLTKLSEaldKLRSYLPKLNPLREEKKKVSV------KSLEE 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  358 KQAQLEKELSTALQDKKCLEEKNEILQGKLSQLEEHLALLrenppqekgEVLGDV-------LQLETLKQEAATLAANNT 430
Cdd:PRK05771    87 LIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL---------EPWGNFdldlsllLGFKYVSVFVGTVPEDKL 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  431 QLQARVETLETEQGQQEAK------LLAERDHFEEekqqLSSLIANLQSS---ISNLSQAKEELEQASQahgarltaQVA 501
Cdd:PRK05771   158 EELKLESDVENVEYISTDKgyvyvvVVVLKELSDE----VEEELKKLGFErleLEEEGTPSELIREIKE--------ELE 225
                          250       260       270
                   ....*....|....*....|....*....|
gi 1622865008  502 SLTSELTTLNATIQQQDQELADLKQQAKEE 531
Cdd:PRK05771   226 EIEKERESLLEELKELAKKYLEELLALYEY 255
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
304-408 4.22e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.38  E-value: 4.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  304 TEKSQMDRKISQLLEENGDLSfKLREFAS--HLQQLQDALNELTEEHSRATQEWLEkqaqlEKELSTALQD-KKCLEEKN 380
Cdd:COG0542    411 EELDELERRLEQLEIEKEALK-KEQDEASfeRLAELRDELAELEEELEALKARWEA-----EKELIEEIQElKEELEQRY 484
                           90       100
                   ....*....|....*....|....*...
gi 1622865008  381 EILQGKLSQLEEHLALLRENPPQEKGEV 408
Cdd:COG0542    485 GKIPELEKELAELEEELAELAPLLREEV 512
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1010-1233 4.50e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1010 TQERGRAQADLALEKAAKAELEMRLQNALNEQRV---EFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQT 1086
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKAllkQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1087 MKQLKEQLAKKEKEhASGSGAQSEAAGRTEPTGPKLEALRAEVskLEQQCQQQQEQADSLERSLEAERASRAERDSALET 1166
Cdd:COG4942     99 LEAQKEELAELLRA-LYRLGRQPPLALLLSPEDFLDAVRRLQY--LKYLAPARREQAEELRADLAELAALRAELEAERAE 175
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622865008 1167 LQGQLEEKARELGHSQSALASVQRELAALRtkvqdhsKAEDEWKAQVARGRQEAERKNSLISSLEEE 1233
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLE-------KELAELAAELAELQQEAEELEALIARLEAE 235
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
688-1694 4.60e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 4.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  688 TEKERVAQEKDqlqEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETrslvEQHKQEQKELEEEKAGRKGL 767
Cdd:pfam01576    1 TRQEEEMQAKE---EELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAET----ELCAEAEEMRARLAARKQEL 73
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  768 EARLQQLGEAHQAETEALRQELAEAIAAQRTAESECEQLVKEVAAWRERYEESQQEEAQYGAMfQEQLMTLKEECEKARQ 847
Cdd:pfam01576   74 EEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKL-EEDILLLEDQNSKLSK 152
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  848 ELQEAKEKVAgieshselqisrqqnelvELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAG 927
Cdd:pfam01576  153 ERKLLEERIS------------------EFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLE 214
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  928 EQQETASRELVKEPARAgdrepEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAAlmeSQGQQQEERGQQEREVA 1007
Cdd:pfam01576  215 GESTDLQEQIAELQAQI-----AELRAQLAKKEEELQAALARLEEETAQKNNALKKIREL---EAQISELQEDLESERAA 286
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1008 RLTQERGRAQADLALEkAAKAELEMRLQ--NALNEQRVEFATLQEALAHAL-TEKEGKDQELVKLRGLEAAQIKELEELR 1084
Cdd:pfam01576  287 RNKAEKQRRDLGEELE-ALKTELEDTLDttAAQQELRSKREQEVTELKKALeEETRSHEAQLQEMRQKHTQALEELTEQL 365
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1085 QTMKQLKEQLAKK----EKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQqcqqqqeqadsleRSLEAERAsRAER 1160
Cdd:pfam01576  366 EQAKRNKANLEKAkqalESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQA-------------RLSESERQ-RAEL 431
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1161 DSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQ----VARGRQEAERKNSLISSLEEEVSI 1236
Cdd:pfam01576  432 AEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQklnlSTRLRQLEDERNSLQEQLEEEEEA 511
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1237 ---LNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSA---LREEVQSLREEAEKQRVASEN 1310
Cdd:pfam01576  512 krnVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAydkLEKTKNRLQQELDDLLVDLDH 591
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1311 LRQELTSQAERAEELGQ---ELKAWQEKFF-QKEQALSTLQLEHTSTQALVSELLPAKHLcQQLQAEQAAAEKRHREELE 1386
Cdd:pfam01576  592 QRQLVSNLEKKQKKFDQmlaEEKAISARYAeERDRAEAEAREKETRALSLARALEEALEA-KEELERTNKQLRAEMEDLV 670
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1387 QSKQAAGGLRAELLRAQREL-GELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAH--GLLAEENRGLGERANLGRQ 1463
Cdd:pfam01576  671 SSKDDVGKNVHELERSKRALeQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFerDLQARDEQGEEKRRQLVKQ 750
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1464 F--LEVELDQAREKYVQELAAVRA-DAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLE-ERQRFQEEKQKLTAQVEQ 1539
Cdd:pfam01576  751 VreLEAELEDERKQRAQAVAAKKKlELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQrELEEARASRDEILAQSKE 830
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1540 LEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKT 1619
Cdd:pfam01576  831 SEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLND 910
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622865008 1620 HYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQqagLKTKEAEQTCR-HLTAQVRSLEAQVAHADQQL 1694
Cdd:pfam01576  911 RLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELK---AKLQEMEGTVKsKFKSSIAALEAKIAQLEEQL 983
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
563-655 5.22e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.86  E-value: 5.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  563 KEQQLKEVAEKQEVTR-RDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQA 641
Cdd:PRK11448   138 EDPENLLHALQQEVLTlKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERKQK 217
                           90
                   ....*....|....
gi 1622865008  642 QREKAELSQKVEEL 655
Cdd:PRK11448   218 RKEITDQAAKRLEL 231
COG3899 COG3899
Predicted ATPase [General function prediction only];
1007-1525 5.60e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 42.15  E-value: 5.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1007 ARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELVKLRGLEAAQIKELEELRQT 1086
Cdd:COG3899    732 LELLPPDPEEEYRLALLLELAEALYLAGRFEEAEALLERALAARALAALAALRHGNPPASARAYANLGLLLLGDYEEAYE 811
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1087 MKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEvskLEQQCQQQQEQADSLERSLEAERASRAERDSALET 1166
Cdd:COG3899    812 FGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELL---REALEAGLETGDAALALLALAAAAAAAAAAAALAA 888
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1167 LQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEG 1246
Cdd:COG3899    889 AAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAA 968
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1247 ESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELG 1326
Cdd:COG3899    969 AAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAA 1048
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1327 QELkawqekffqkEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQREL 1406
Cdd:COG3899   1049 LAA----------AAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAA 1118
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1407 GELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRAD 1486
Cdd:COG3899   1119 ALAALALAAAARAAAALLLLAAALALALAALLLLAALLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAA 1198
                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 1622865008 1487 AETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQR 1525
Cdd:COG3899   1199 LLALAARLAALLALALLALEAAALLLLLLLAALALAAAL 1237
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1456-1662 5.68e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 5.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1456 ERANLGRQFLEVELDQAREKYVQ-ELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEEKQKLT 1534
Cdd:COG3206    171 EEARKALEFLEEQLPELRKELEEaEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLG 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1535 AQVEQLEVFQreQTKQVEELRKKLADsdqaskvQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAehyklqM 1614
Cdd:COG3206    251 SGPDALPELL--QSPVIQQLRAQLAE-------LEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRI------L 315
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1622865008 1615 EKAKTHYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQA 1662
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVA 363
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
914-1334 5.82e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 5.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  914 KEVARLETLVRKAGEQQETASRELVKEPARAGDREPEWLEEQQGRQfcSTQAALQAMEREAEQMGNELERLRAALmeSQG 993
Cdd:COG4717     53 KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELE--ELEEELEELEAELEELREELEKLEKLL--QLL 128
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  994 QQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELVKLRGLE 1073
Cdd:COG4717    129 PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRL 208
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1074 AAQIKELEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGpkLEALRAEVSKLEQQCQQQQEQADSLERSLEAE 1153
Cdd:COG4717    209 AELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLI--AAALLALLGLGGSLLSLILTIAGVLFLVLGLL 286
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1154 RASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEE 1233
Cdd:COG4717    287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1234 VSILNRQVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQ 1313
Cdd:COG4717    367 ELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEE 446
                          410       420
                   ....*....|....*....|.
gi 1622865008 1314 ELTSQAERAEELGQELKAWQE 1334
Cdd:COG4717    447 ELEELREELAELEAELEQLEE 467
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1481-1721 5.88e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 5.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1481 AAVRADAETRLAEVQREAQSTARELEvmtakyegakvKVLEERQRFQEEKQKLTAQVEQLEVFQREQTKQVEELRKKLAD 1560
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELA-----------ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1561 SDQASKVQQQKLKAVQAQGGESQQEAQRLqARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAK-----KQQNQELQEQL 1635
Cdd:COG4942     88 LEKEIAELRAELEAQKEELAELLRALYRL-GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREqaeelRADLAELAALR 166
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1636 QSLEHLQKENKELRAEAERLGHELQQAglkTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAK 1715
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEAL---KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243

                   ....*.
gi 1622865008 1716 PQLDLS 1721
Cdd:COG4942    244 PAAGFA 249
PRK12705 PRK12705
hypothetical protein; Provisional
583-741 6.04e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 41.62  E-value: 6.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  583 QQLATAAEEREASLReRDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETA 662
Cdd:PRK12705    29 QRLAKEAERILQEAQ-KEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDNLENQL 107
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622865008  663 CREQHEAQAQVAELEfqlQSEQQKATEKERVAQekdqlQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKA 741
Cdd:PRK12705   108 EEREKALSARELELE---ELEKQLDNELYRVAG-----LTPEQARKLLLKLLDAELEEEKAQRVKKIEEEADLEAERKA 178
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
1397-1699 6.42e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 6.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1397 AELLRAQRELGELiplRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHG---LLAEEnrGLGERanlgRQFLEVELDQAR 1473
Cdd:COG3096    836 AELAALRQRRSEL---ERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPqanLLADE--TLADR----LEELREELDAAQ 906
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1474 E--KYVQElaavRADAETRLAEVQREAQSTARELEVMTAKYEGAKvkvleerqrfqEEKQKLTAQVEQL-EVFQREQTKQ 1550
Cdd:COG3096    907 EaqAFIQQ----HGKALAQLEPLVAVLQSDPEQFEQLQADYLQAK-----------EQQRRLKQQIFALsEVVQRRPHFS 971
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1551 VEELRKKLADSDQASKVQQQKLKavqaqggesQQEAQRLQAR--LNELQAQLSQKEQAaehyklqMEKAKTHYDAKKQQN 1628
Cdd:COG3096    972 YEDAVGLLGENSDLNEKLRARLE---------QAEEARREAReqLRQAQAQYSQYNQV-------LASLKSSRDAKQQTL 1035
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622865008 1629 QELQEQLQSLEHLQKENKELRAEAERlgHELQQAGLKTKeaeQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1699
Cdd:COG3096   1036 QELEQELEELGVQADAEAEERARIRR--DELHEELSQNR---SRRSQLEKQLTRCEAEMDSLQKRLRKAER 1101
PRK12704 PRK12704
phosphodiesterase; Provisional
582-749 6.62e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 6.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  582 AQQLATAAEEREASLRErdAALQQLEALEKEK--AAKLEILQQQLQVANETRDSAQtsvtQAQREKAELSQKVEELRARV 659
Cdd:PRK12704    29 AEAKIKEAEEEAKRILE--EAKKEAEAIKKEAllEAKEEIHKLRNEFEKELRERRN----ELQKLEKRLLQKEENLDRKL 102
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  660 ETACREQHEAQAQVAELEFQLQSEQQKATEKERVaqekdqLQEQLQALKESLKVTKgslEEEKRRAADALEEqqrcisEL 739
Cdd:PRK12704   103 ELLEKREEELEKKEKELEQKQQELEKKEEELEEL------IEEQLQELERISGLTA---EEAKEILLEKVEE------EA 167
                          170
                   ....*....|
gi 1622865008  740 KAETRSLVEQ 749
Cdd:PRK12704   168 RHEAAVLIKE 177
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
423-785 6.72e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.04  E-value: 6.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  423 ATLAANNTQLQARVETLETEQGQQEAKLLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQAsQAHGARLTAQVAS 502
Cdd:COG4372     27 AALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAA-QAELAQAQEELES 105
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  503 LTSELTTLNATIQQQDQELADLKQQAKEeqaqlaqtlqqqeqasqgLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHA 582
Cdd:COG4372    106 LQEEAEELQEELEELQKERQDLEQQRKQ------------------LEAQIAELQSEIAEREEELKELEEQLESLQEELA 167
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  583 QQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETA 662
Cdd:COG4372    168 ALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEED 247
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  663 CREQHEAQAQVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAE 742
Cdd:COG4372    248 KEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKK 327
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1622865008  743 TRSLVEQHKQEQKELEEEKAGRKGLEARLQQLGEAHQAETEAL 785
Cdd:COG4372    328 LELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGVADG 370
PRK12704 PRK12704
phosphodiesterase; Provisional
561-662 7.15e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 7.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  561 KQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAAL----QQLEALEKEKAAKLEILQQQLQVANETRDSAQT 636
Cdd:PRK12704    63 KEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLekreEELEKKEKELEQKQQELEKKEEELEELIEEQLQ 142
                           90       100       110
                   ....*....|....*....|....*....|.
gi 1622865008  637 ---SVTQAQRE--KAELSQKVEElRARVETA 662
Cdd:PRK12704   143 eleRISGLTAEeaKEILLEKVEE-EARHEAA 172
PLN02939 PLN02939
transferase, transferring glycosyl groups
251-494 7.22e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 41.43  E-value: 7.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  251 IAMMQQRIDRLALLNEK--QAASPLEP--RELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKISQLLEENGDLSFK 326
Cdd:PLN02939   134 VGMIQNAEKNILLLNQArlQALEDLEKilTEKEALQGKINILEMRLSETDARIKLAAQEKIHVEILEEQLEKLRNELLIR 213
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  327 LREFASHLQQLQDALNELTEEH------SRATQEWLEKQAQLEKELSTALQDKKCLEEKNEILQGKLSQLEE---HLALL 397
Cdd:PLN02939   214 GATEGLCVHSLSKELDVLKEENmllkddIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEdvsKLSPL 293
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  398 RENPPQEKGEVLGDVLQLETLKQE-AATLAANNTQLQARVETLETEQG---------------QQEAKLLAErdHFEEEK 461
Cdd:PLN02939   294 QYDCWWEKVENLQDLLDRATNQVEkAALVLDQNQDLRDKVDKLEASLKeanvskfssykvellQQKLKLLEE--RLQASD 371
                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1622865008  462 QQLSSLIANLQSSIS----NLSQAKEELEQASQAHGA 494
Cdd:PLN02939   372 HEIHSYIQLYQESIKefqdTLSKLKEESKKRSLEHPA 408
valS PRK05729
valyl-tRNA synthetase; Reviewed
1465-1598 7.28e-03

valyl-tRNA synthetase; Reviewed


Pssm-ID: 235582 [Multi-domain]  Cd Length: 874  Bit Score: 41.63  E-value: 7.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1465 LEVELDQAREKYVQELAAVRADAE--TRLAEVQREAQSTARELEVMTAKYEGAKVKV-LE-------ERQRFQEEKQKLT 1534
Cdd:PRK05729   745 LPLLLKGADAEDRARLEANEAYIKrlARLESLEILADDEEAPEGAASAVVGGAELFLpLEglidveaELARLEKELAKLE 824
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622865008 1535 AQVEQLEvfqreqtkqveelrKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQA 1598
Cdd:PRK05729   825 KEIERVE--------------KKLSNEGFVAKAPEEVVEKEREKLAEYEEKLAKLKERLARLKA 874
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
215-399 7.39e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.54  E-value: 7.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL----ALLNEKQAASPLEPRELE-ELRDKNESLt 289
Cdd:TIGR04523  469 QLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLtkkiSSLKEKIEKLESEKKEKEsKISDLEDEL- 547
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  290 MRLHETLKQCQdLKTEKSQMDRKISQLLEENGDLSFKLREFASHLQQLQDALNELTEEHSRATQewleKQAQLEKELSTA 369
Cdd:TIGR04523  548 NKDDFELKKEN-LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEK----KISSLEKELEKA 622
                          170       180       190
                   ....*....|....*....|....*....|
gi 1622865008  370 LQDKKCLEEKNEILQGKLSQLEEHLALLRE 399
Cdd:TIGR04523  623 KKENEKLSSIIKNIKSKKNKLKQEVKQIKE 652
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
337-697 7.52e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.03  E-value: 7.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  337 LQDALNELTEEHSRATQEWLEKQAQLEKELSTALQDKKCLEEKNEILQGKLSQLEEHLALLRENPPQEKGEVLGDVLQLE 416
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSE 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  417 TLKQEAATLAANNTQLQARVETLE------TEQG-----------QQEAKLLAERDHFEEEKQQLSsliANLQSSISNLS 479
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIRELEediktlTQRVleretelermkERAKKAGAQRKEEEAERKQLQ---AKLQQTEEELR 188
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  480 QAKEELEQASQAHGARLTaQVASLTSELTTLNATIQQQDQELADLkQQAKEEQAQLAQTLQQQEQASQGLRhqvEQLSSS 559
Cdd:pfam07888  189 SLSKEFQELRNSLAQRDT-QVLQLQDTITTLTQKLTTAHRKEAEN-EALLEELRSLQERLNASERKVEGLG---EELSSM 263
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  560 LKQKEQQLKEV--AEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLEILQQQLQvanetrDSAQTS 637
Cdd:pfam07888  264 AAQRDRTQAELhqARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLE------ERLQEE 337
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622865008  638 VTQAQREKAELSQKVEELRARVETACREQHEAQA--QVAELEF-QLQSEQQKATEKERVAQEK 697
Cdd:pfam07888  338 RMEREKLEVELGREKDCNRVQLSESRRELQELKAslRVAQKEKeQLQAEKQELLEYIRQLEQR 400
PRK01156 PRK01156
chromosome segregation protein; Provisional
220-734 7.60e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.43  E-value: 7.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  220 KKQLADERSNRDELElelaENRKLLTEkdaQIAMMQQRIDRLALLNEKQAASPLEPRELE---ELRDKNESLTMRLHETL 296
Cdd:PRK01156   151 RKKILDEILEINSLE----RNYDKLKD---VIDMLRAEISNIDYLEEKLKSSNLELENIKkqiADDEKSHSITLKEIERL 223
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  297 KQCQDLKTEKSQMD----RKISQLLEENGDLSFKLREFASHLQQLQDALN---ELTEEHSRATQEWLEKQaqlEKELSTA 369
Cdd:PRK01156   224 SIEYNNAMDDYNNLksalNELSSLEDMKNRYESEIKTAESDLSMELEKNNyykELEERHMKIINDPVYKN---RNYINDY 300
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  370 LQDKKCLEEKNEILQGKLSQLEEHLALLR------------ENPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVE 437
Cdd:PRK01156   301 FKYKNDIENKKQILSNIDAEINKYHAIIKklsvlqkdyndyIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIE 380
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  438 TLETEQ-----------GQQEAK---LLAERDHFEEEKQQLSSLIANLQSSISNLSQAKEELEQASQAHGARLTAQVASL 503
Cdd:PRK01156   381 EYSKNIermsafiseilKIQEIDpdaIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGT 460
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  504 T--------------SELTTLNATIQQQDQELADLKQQAKEEQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKE 569
Cdd:PRK01156   461 TlgeeksnhiinhynEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINE 540
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  570 VAEKQevtrrdhaqqlataaeereaslrerdaaLQQLEALEKEKAAKLEILQQQLQV---ANETRDSAQTSVTQAQREka 646
Cdd:PRK01156   541 LKDKH----------------------------DKYEEIKNRYKSLKLEDLDSKRTSwlnALAVISLIDIETNRSRSN-- 590
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  647 ELSQKVEELRARVETACREQHEAQA----QVAELEFQLQSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEK 722
Cdd:PRK01156   591 EIKKQLNDLESRLQEIEIGFPDDKSyidkSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLK 670
                          570
                   ....*....|..
gi 1622865008  723 RRAADALEEQQR 734
Cdd:PRK01156   671 EITSRINDIEDN 682
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
1163-1305 8.07e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 8.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1163 ALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVAR--GRQEAERKNSLISSLEEEVSILNRQ 1240
Cdd:COG1579     25 RLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKyeEQLGNVRNNKEYEALQKEIESLKRR 104
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622865008 1241 VLEKEGESKELKRLVMAESEKSQKLEDRLRLLQAETASNSARAAERSSALREEVQSLREEAEKQR 1305
Cdd:COG1579    105 ISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELA 169
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
607-741 8.26e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.38  E-value: 8.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  607 EALEKEKAaklEILQQQLQVANETRDSAQTSVTQAQREKAELSQKVEELRARVETACREQHEAQAQVAELEFQLQSEQQK 686
Cdd:COG2433    380 EALEELIE---KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE 456
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622865008  687 ATEKERVAQEkdqlqeqLQALKESLKVTKGSLEEEKRRaadaLEEQQRCISELKA 741
Cdd:COG2433    457 ERREIRKDRE-------ISRLDREIERLERELEEERER----IEELKRKLERLKE 500
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
1180-1276 8.37e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.48  E-value: 8.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1180 HSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQ--VLEKEGESKELKRLvMA 1257
Cdd:PRK11448   139 DPENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQleQLQEKAAETSQERK-QK 217
                           90
                   ....*....|....*....
gi 1622865008 1258 ESEKSQKLEDRLRLLQAET 1276
Cdd:PRK11448   218 RKEITDQAAKRLELSEEET 236
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
1227-1330 8.52e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.22  E-value: 8.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1227 ISSLEEEVSILNRQVLEKEGESKELKRLVMAES-EKSQKLEDRLRLLQAETASNSARaAERSSALREEVQSLREEAEKQR 1305
Cdd:COG0542    406 IDSKPEELDELERRLEQLEIEKEALKKEQDEASfERLAELRDELAELEEELEALKAR-WEAEKELIEEIQELKEELEQRY 484
                           90       100
                   ....*....|....*....|....*
gi 1622865008 1306 VASENLRQELTSQAERAEELGQELK 1330
Cdd:COG0542    485 GKIPELEKELAELEEELAELAPLLR 509
MAP65_ASE1 pfam03999
Microtubule associated protein (MAP65/ASE1 family);
549-742 9.58e-03

Microtubule associated protein (MAP65/ASE1 family);


Pssm-ID: 427641 [Multi-domain]  Cd Length: 477  Bit Score: 40.76  E-value: 9.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  549 LRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEEREASLRERDAALQQLEALEKEKAAKLE----ILQQQL 624
Cdd:pfam03999   95 LDTQLEHLRKEKAPRLAEIKELLEQLQQLCEELGEEPLPLLIDPLPSLEELESFRKHLENLRNEKERRLEevneLKKQIK 174
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008  625 QVANETRDSAQTSVTQAQREKAELSQKVEelRARVETACREQHEAQAQVAELEfqlqseqqkatekervaQEKDQLQEQL 704
Cdd:pfam03999  175 LLMEELDLVPGTDFEEDLLCESEDNFCLS--RENIDKLRKLIKQLEEQKAERE-----------------EKIDDLREKI 235
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1622865008  705 QALKESLKVtkgSLEEEKRRAADALEEQQRCISELKAE 742
Cdd:pfam03999  236 LELWNRLQV---PQEEQESFVRENNSLSQDTIDALREE 270
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
1080-1311 9.65e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 40.96  E-value: 9.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1080 LEELRQTMKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAE 1159
Cdd:pfam10174  354 LEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSN 433
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622865008 1160 RDSALETLQGQLEEKARELGHSQSALASVQRElaaLRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNR 1239
Cdd:pfam10174  434 TDTALTTLEEALSEKERIIERLKEQREREDRE---RLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLAS 510
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622865008 1240 QVLEKEGESKELKRLVMAESEKSQKLEDRLRLLQ--AETASNSARAAERSSALREEVQSLREEAEKQRVASENL 1311
Cdd:pfam10174  511 SGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHnaEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERL 584
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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