|
Name |
Accession |
Description |
Interval |
E-value |
| INCENP_N |
pfam12178 |
Chromosome passenger complex (CPC) protein INCENP N terminal; This domain family is found in ... |
6-41 |
5.94e-17 |
|
Chromosome passenger complex (CPC) protein INCENP N terminal; This domain family is found in eukaryotes, and is approximately 40 amino acids in length. INCENP is a regulatory protein in the chromosome passenger complex. It is involved in regulation of the catalytic protein Aurora B. It performs this function in association with two other proteins - Survivin and Borealin. These proteins form a tight three-helical bundle. The N terminal domain is the domain involved in formation of this three helical bundle.
Pssm-ID: 463484 [Multi-domain] Cd Length: 36 Bit Score: 75.04 E-value: 5.94e-17
10 20 30
....*....|....*....|....*....|....*.
gi 966984660 6 PGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEA 41
Cdd:pfam12178 1 SGPASLLEVCDQKLSEFLCEIDNKHLVWLEEIEEEA 36
|
|
| INCENP_ARK-bind |
pfam03941 |
Inner centromere protein, ARK binding region; This region of the inner centromere protein has ... |
801-855 |
3.01e-15 |
|
Inner centromere protein, ARK binding region; This region of the inner centromere protein has been found to be necessary and sufficient for binding to aurora-related kinase. This interaction has been implicated in the coordination of chromosome segregation with cell division in yeast.
Pssm-ID: 461100 [Multi-domain] Cd Length: 53 Bit Score: 70.69 E-value: 3.01e-15
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 966984660 801 NSDDSTDDEAHPRKPIPNWARGTPLSQAIIHQYyhPPNLLELFGAILPLDLEDIF 855
Cdd:pfam03941 1 NSDDEDDDEDEPRKPVPSWAQSPNLRQALIRQE--PIDPDEIFGPIPPLNLEEIF 53
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-756 |
2.80e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 74.41 E-value: 2.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREErLRKVLQARERVEQMK--EEKKKQIEQKFAQIDEKTEK 606
Cdd:PTZ00121 1570 KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEE-AKKAEEAKIKAEELKkaEEEKKKVEQLKKKEAEEKKK 1648
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 607 AKEERlaeekakKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ---ERLRKA-AEAKRLAEQR 682
Cdd:PTZ00121 1649 AEELK-------KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAkkaEELKKKeAEEKKKAEEL 1721
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966984660 683 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 756
Cdd:PTZ00121 1722 KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRME 1795
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-755 |
5.08e-12 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 70.17 E-value: 5.08e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKR-----RRLEEVK----LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQ 599
Cdd:PTZ00121 1505 AAEAKKKADEAKKAEEAKKADEAKKAEEAKkadeaKKAEEKKkadeLKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAE 1584
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 600 IDEKTEKAKEERLaeekaKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ---ERLRKAAEAK 676
Cdd:PTZ00121 1585 EAKKAEEARIEEV-----MKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKkkaEELKKAEEEN 1659
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966984660 677 RLAEQREQERREQERQLAEQERrreqerlQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 755
Cdd:PTZ00121 1660 KIKAAEEAKKAEEDKKKAEEAK-------KAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIK 1731
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
530-758 |
5.38e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 69.97 E-value: 5.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 530 EKERQRLENLRRKEEAEQLRRQKVEEDKrRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 609
Cdd:COG1196 270 EELRLELEELELELEEAQAEEYELLAEL-ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 610 ERlaeekaKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 689
Cdd:COG1196 349 AE------EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966984660 690 ERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA 758
Cdd:COG1196 423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-757 |
1.99e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 68.24 E-value: 1.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK---------EEKKKQIEQKFAQ 599
Cdd:PTZ00121 1285 KAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKkaaeaakaeAEAAADEAEAAEE 1364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 600 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ---ERLRKAAEAK 676
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKkadEAKKKAEEAK 1444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 677 RLAEQREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK--ERLQRELEEKKKKEEQQRLAERQLQEEQEKKA 754
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKkaEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA 1524
|
...
gi 966984660 755 KEA 757
Cdd:PTZ00121 1525 DEA 1527
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
519-724 |
4.41e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.09 E-value: 4.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 519 KRNTPLRVDPKEKERQRLENLRRKEE----AEQLRRqkvEEDKRRRLEEVKLKREERLRKVLQARERVEQMK----EEKK 590
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEEAKKAEEakikAEELKK---AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKikaaEEAK 1668
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 591 KQIEQKfaQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQErlR 670
Cdd:PTZ00121 1669 KAEEDK--KKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDK--K 1744
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 966984660 671 KAAEAKRLAEQREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKER 724
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
529-764 |
7.24e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 66.11 E-value: 7.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKfAQIDEKTEKAK 608
Cdd:COG1196 244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR-RELEERLEELE 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 609 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 688
Cdd:COG1196 323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966984660 689 QERQLAEQERRREQERLQAER-ELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGVSKAL 764
Cdd:COG1196 403 EELEEAEEALLERLERLEEELeELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-764 |
8.61e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 66.32 E-value: 8.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKR----RRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIdEKT 604
Cdd:PTZ00121 1547 KADELKKAEELKKAEEKKKAEEAKKAEEDKnmalRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA-EEL 1625
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 605 EKAKEERlaeekakkkaaakkMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER----LRKAAEAKRLAE 680
Cdd:PTZ00121 1626 KKAEEEK--------------KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKkaeeAKKAEEDEKKAA 1691
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 681 QREQERREQERQLAEQERRREQERLQAErELQEREKALRLQKERLQRELEEKKKKEEQQRLAE------RQLQEEQEKKA 754
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEeekkkiAHLKKEEEKKA 1770
|
250
....*....|
gi 966984660 755 KEAAGVSKAL 764
Cdd:PTZ00121 1771 EEIRKEKEAV 1780
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
529-766 |
1.20e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 65.34 E-value: 1.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQK-VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKA 607
Cdd:COG1196 281 LELEEAQAEEYELLAELARLEQDIaRLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 608 KEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRwlqQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 687
Cdd:COG1196 361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAA---ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966984660 688 EQERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGVSKALNV 766
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
530-764 |
8.85e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 62.65 E-value: 8.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 530 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKfaQIDEKTEKAKE 609
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI--ARLEERRRELE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 610 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 689
Cdd:COG1196 316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966984660 690 ERQLAeqerrREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGVSKAL 764
Cdd:COG1196 396 AELAA-----QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-757 |
1.11e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.47 E-value: 1.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRK-EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK--------EEKKKQIEQKFAQ 599
Cdd:PTZ00121 1452 KAEEAKKAEEAKKKaEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKkadeakkaEEAKKADEAKKAE 1531
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 600 IDEKTE---KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ--------EEEERRHQELLQKKKEEEQER 668
Cdd:PTZ00121 1532 EAKKADeakKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKaeeakkaeEARIEEVMKLYEEEKKMKAEE 1611
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 669 LRKAAEAKRLAEQreqerreqerqLAEQERRREQERLQAERELQEREKALRLQKE----RLQRELEEKKKKEEQQRLAER 744
Cdd:PTZ00121 1612 AKKAEEAKIKAEE-----------LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAeeenKIKAAEEAKKAEEDKKKAEEA 1680
|
250
....*....|...
gi 966984660 745 QLQEEQEKKAKEA 757
Cdd:PTZ00121 1681 KKAEEDEKKAAEA 1693
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
529-756 |
8.53e-09 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 59.37 E-value: 8.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQK--VEEDKRRRLEEVKLKRE---ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK 603
Cdd:pfam17380 346 RERELERIRQEERKRELERIRQEEiaMEISRMRELERLQMERQqknERVRQELEAARKVKILEEERQRKIQQQKVEMEQI 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 604 TEKAKEERlaeekakkkaaakkmeEVEARRKQEEEARRLRWLQQEEEERRHQelLQKKKEEEQERLRKAAEAKRLAEQRE 683
Cdd:pfam17380 426 RAEQEEAR----------------QREVRRLEEERAREMERVRLEEQERQQQ--VERLRQQEEERKRKKLELEKEKRDRK 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 684 QERREQERQLAEQERRREQERLQAER-------ELQEREKALRLQKERLQREleekKKKEEQQRLAERQLQEEQEKKAKE 756
Cdd:pfam17380 488 RAEEQRRKILEKELEERKQAMIEEERkrkllekEMEERQKAIYEEERRREAE----EERRKQQEMEERRRIQEQMRKATE 563
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-757 |
1.19e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.38 E-value: 1.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREER----------LRKVLQARERVEQMKEEKKKQIEQKFA 598
Cdd:PTZ00121 1207 KAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERnneeirkfeeARMAHFARRQAAIKAEEARKADELKKA 1286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 599 QIDEKTEKAKE-ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR 677
Cdd:PTZ00121 1287 EEKKKADEAKKaEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKA 1366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 678 LAEQREQERREQERQLAEQERRREQERLQAERELQE-REKALRLQKerlqRELEEKKKKEEQQRLAERQLQEEQEKKAKE 756
Cdd:PTZ00121 1367 EAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdKKKADELKK----AAAAKKKADEAKKKAEEKKKADEAKKKAEE 1442
|
.
gi 966984660 757 A 757
Cdd:PTZ00121 1443 A 1443
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-763 |
1.26e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.00 E-value: 1.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK---EEKKKQIEQKFAqiDEKTE 605
Cdd:PTZ00121 1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKkadEAKKKAEEKKKA--DEAKK 1438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 606 KAKEERlaeEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ---ERLRKAAEAKRLAEQR 682
Cdd:PTZ00121 1439 KAEEAK---KADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKkkaDEAKKAAEAKKKADEA 1515
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 683 EQERREQERQLAEQERRREQErlQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERqlQEEQEKKAKEAAGVSK 762
Cdd:PTZ00121 1516 KKAEEAKKADEAKKAEEAKKA--DEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED--KNMALRKAEEAKKAEE 1591
|
.
gi 966984660 763 A 763
Cdd:PTZ00121 1592 A 1592
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-763 |
1.29e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.00 E-value: 1.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEE-----AEQLRR---QKVEEDKRRRLEEVklKREERLRKVLQARERVEQMK-EEKKKQIEQKFAq 599
Cdd:PTZ00121 1478 KAEEAKKADEAKKKAEeakkkADEAKKaaeAKKKADEAKKAEEA--KKADEAKKAEEAKKADEAKKaEEKKKADELKKA- 1554
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 600 idEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ---ERLRKAAEAK 676
Cdd:PTZ00121 1555 --EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKikaEELKKAEEEK 1632
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 677 RLAEQREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKaKE 756
Cdd:PTZ00121 1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK-KE 1711
|
....*..
gi 966984660 757 AAGVSKA 763
Cdd:PTZ00121 1712 AEEKKKA 1718
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-757 |
2.80e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.84 E-value: 2.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAeqlrrQKVEEDKR----RRLEEVKlKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKT 604
Cdd:PTZ00121 1201 KAEAARKAEEERKAEEA-----RKAEDAKKaeavKKAEEAK-KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA 1274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 605 EKA-KEERLAEEKAKKKAAAKkmeevearrKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL----RKAAEAKRLA 679
Cdd:PTZ00121 1275 EEArKADELKKAEEKKKADEA---------KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAdaakKKAEEAKKAA 1345
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966984660 680 EQREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 757
Cdd:PTZ00121 1346 EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEA 1423
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
520-764 |
3.14e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 57.67 E-value: 3.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 520 RNTPLRVDPKEKERQRLENLRRKEEAEQLRR-----QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIE 594
Cdd:pfam02463 196 KLQELKLKEQAKKALEYYQLKEKLELEEEYLlyldyLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENK 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 595 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 674
Cdd:pfam02463 276 EEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEE 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 675 AKRLAEQREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQREleekkkkeeQQRLAERQLQEEQEKKA 754
Cdd:pfam02463 356 EEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQL---------LLELARQLEDLLKEEKK 426
|
250
....*....|
gi 966984660 755 KEAAGVSKAL 764
Cdd:pfam02463 427 EELEILEEEE 436
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
537-757 |
3.23e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.84 E-value: 3.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 537 ENLRRKEEAEQLRRQKVEEDkrRRLEEVKlKREERLRKVLQARERVEQMK-EEKKKQIEQKFAQIDEKTEKAKEERLAEE 615
Cdd:PTZ00121 1095 EAFGKAEEAKKTETGKAEEA--RKAEEAK-KKAEDARKAEEARKAEDARKaEEARKAEDAKRVEIARKAEDARKAEEARK 1171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 616 KAKKKAAAKKMEEVEARRKQE----EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR---LAEQREQERRE 688
Cdd:PTZ00121 1172 AEDAKKAEAARKAEEVRKAEElrkaEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKdaeEAKKAEEERNN 1251
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966984660 689 QERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 757
Cdd:PTZ00121 1252 EEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEA 1320
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
526-757 |
3.37e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.84 E-value: 3.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 526 VDPKEKERQRLENLRRKEE---------AEQLRRQ---KVEE----DKRRRLEEVK----LKREERLRKVLQARERVEQM 585
Cdd:PTZ00121 1235 AKKDAEEAKKAEEERNNEEirkfeearmAHFARRQaaiKAEEarkaDELKKAEEKKkadeAKKAEEKKKADEAKKKAEEA 1314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 586 K---------EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQE 656
Cdd:PTZ00121 1315 KkadeakkkaEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD 1394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 657 LLQKKKEEEQ---ERLRKAAEAKRLAEQ-REQERREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQ-RELEE 731
Cdd:PTZ00121 1395 EAKKKAEEDKkkaDELKKAAAAKKKADEaKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEaKKADE 1474
|
250 260
....*....|....*....|....*...
gi 966984660 732 KKKKEEQQRLAE--RQLQEEQEKKAKEA 757
Cdd:PTZ00121 1475 AKKKAEEAKKADeaKKKAEEAKKKADEA 1502
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-756 |
4.13e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.46 E-value: 4.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRlEEVKLKREERlRKVLQARERVEQMK----EEKKKQIEQKFAqiDEKT 604
Cdd:PTZ00121 1349 KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKA-DAAKKKAEEK-KKADEAKKKAEEDKkkadELKKAAAAKKKA--DEAK 1424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 605 EKAKEERlaeEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ---ERLRKAAEAKRLAEQ 681
Cdd:PTZ00121 1425 KKAEEKK---KADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKkadEAKKKAEEAKKKADE 1501
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966984660 682 REQERREQERQLAEQERRREQERLQAeRELQEREKALRLQKERLQRElEEKKKKEEQQRLAERQLQEEQEKKAKE 756
Cdd:PTZ00121 1502 AKKAAEAKKKADEAKKAEEAKKADEA-KKAEEAKKADEAKKAEEKKK-ADELKKAEELKKAEEKKKAEEAKKAEE 1574
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
530-765 |
5.78e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.87 E-value: 5.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 530 EKERQrLENLRRkeEAEQLRR-QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 608
Cdd:COG1196 197 ELERQ-LEPLER--QAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 609 EERLAEEKakkkaaakkmeevEARRKQEEEArrlrwlqqeeeerrhqeLLQKKKEEEQERLRKAAEAKRLAEQREQERRE 688
Cdd:COG1196 274 LELEELEL-------------ELEEAQAEEY-----------------ELLAELARLEQDIARLEERRRELEERLEELEE 323
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966984660 689 QERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGVSKALN 765
Cdd:COG1196 324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
529-764 |
6.74e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 56.52 E-value: 6.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEE--AEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEK 606
Cdd:pfam02463 168 KRKKKEALKKLIEETEnlAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLR 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 607 AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRlrwLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 686
Cdd:pfam02463 248 DEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966984660 687 REQErqlAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGVSKAL 764
Cdd:pfam02463 325 KAEK---ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELEL 399
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-758 |
7.47e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 56.69 E-value: 7.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEE---AEQLRR----QKVEEDKR----RRLEEVK----LKREERLRKVLQARERVEQMKEEKKKQI 593
Cdd:PTZ00121 1171 KAEDAKKAEAARKAEEvrkAEELRKaedaRKAEAARKaeeeRKAEEARkaedAKKAEAVKKAEEAKKDAEEAKKAEEERN 1250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 594 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE-----EARRLRWLQQEEEERRHQELLQKKKEEEQER 668
Cdd:PTZ00121 1251 NEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEakkaeEKKKADEAKKKAEEAKKADEAKKKAEEAKKK 1330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 669 L----RKAAEAKRLAEQREQERREQERQLAEQERRREQERLQAERElQEREKALRLQKERLQRELEEKKKKEEQQRLAER 744
Cdd:PTZ00121 1331 AdaakKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEA-KKKADAAKKKAEEKKKADEAKKKAEEDKKKADE 1409
|
250
....*....|....
gi 966984660 745 QLQEEQEKKAKEAA 758
Cdd:PTZ00121 1410 LKKAAAAKKKADEA 1423
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
518-675 |
1.00e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 56.30 E-value: 1.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 518 IKRNTPLRVDPKEKERQRLENLRRKEEAEQLRR----QKVEEDKR-----RRLEEVKLKREERLRKVLQARERVEQMKee 588
Cdd:PTZ00121 1631 EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAaeeaKKAEEDKKkaeeaKKAEEDEKKAAEALKKEAEEAKKAEELK-- 1708
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 589 KKKQIEQKFAqidEKTEKAKEERLAEEKakkkaaakkmeevEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 668
Cdd:PTZ00121 1709 KKEAEEKKKA---EELKKAEEENKIKAE-------------EAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEE 1772
|
....*..
gi 966984660 669 LRKAAEA 675
Cdd:PTZ00121 1773 IRKEKEA 1779
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
530-756 |
2.11e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.15 E-value: 2.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 530 EKERQRLENLRRKEEAEQLRRQ-KVEEDKRRRLEEVKLKREERlRKVLQARERVEQMK--EEKKKQIEQKfAQIDEKTEK 606
Cdd:PTZ00121 1401 EEDKKKADELKKAAAAKKKADEaKKKAEEKKKADEAKKKAEEA-KKADEAKKKAEEAKkaEEAKKKAEEA-KKADEAKKK 1478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 607 AKEERlAEEKAKKKAAAKKMEEVEARRKQEE--EARRLRWLQQEEEERRHQELLQKKKEEE---QERLRKAAEAKRlAEQ 681
Cdd:PTZ00121 1479 AEEAK-KADEAKKKAEEAKKKADEAKKAAEAkkKADEAKKAEEAKKADEAKKAEEAKKADEakkAEEKKKADELKK-AEE 1556
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966984660 682 REQERREQERQLAEQERRREQERLQAERELQEREKAlRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 756
Cdd:PTZ00121 1557 LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEA-RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE 1630
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
530-763 |
5.55e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.61 E-value: 5.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 530 EKERQRLENLRRKEEAEQLRRQKVEEDKrrrlEEVKLKREERLRKVLQARERVEQMK--EEKKKQIEQKFAQIDEkTEKA 607
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAAEEKA----EAAEKKKEEAKKKADAAKKKAEEKKkaDEAKKKAEEDKKKADE-LKKA 1413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 608 KEERLAEEKAKKKaaAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ--ERLRKAAEAKRLAEQREQE 685
Cdd:PTZ00121 1414 AAAKKKADEAKKK--AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKkaDEAKKKAEEAKKADEAKKK 1491
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 686 RREQERQlAEQERRREQERLQAE--RELQEREKALRLQKERLQRElEEKKKKEEQQRLAERQLQEEQEKKAKEAAGVSKA 763
Cdd:PTZ00121 1492 AEEAKKK-ADEAKKAAEAKKKADeaKKAEEAKKADEAKKAEEAKK-ADEAKKAEEKKKADELKKAEELKKAEEKKKAEEA 1569
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-762 |
9.54e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.84 E-value: 9.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEE---AEQLRR----QKVEEDKR----RRLEEVK----LKREERLRKVLQARERVEQMKEEKKKQI 593
Cdd:PTZ00121 1117 AEEAKKKAEDARKAEEarkAEDARKaeeaRKAEDAKRveiaRKAEDARkaeeARKAEDAKKAEAARKAEEVRKAEELRKA 1196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 594 EQkfAQIDEKTEKAKEERLAEEKAKKKAAAKKME--EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLrK 671
Cdd:PTZ00121 1197 ED--ARKAEAARKAEEERKAEEARKAEDAKKAEAvkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAI-K 1273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 672 AAEAKRLAEQREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQE 751
Cdd:PTZ00121 1274 AEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAE 1353
|
250
....*....|.
gi 966984660 752 KKAKEAAGVSK 762
Cdd:PTZ00121 1354 AAADEAEAAEE 1364
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
530-757 |
1.26e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.45 E-value: 1.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 530 EKERQRLENLRRKEEAEQLRRQKVEEDKRRrLEEVKL----KREERLRKVLQARERVEQMKEEKKKQIEQkfAQIDEKTE 605
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARK-AEEARKaedaKRVEIARKAEDARKAEEARKAEDAKKAEA--ARKAEEVR 1188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 606 KAKEERlaeekakkkaAAKKMEEVEARRKQEEEAR--RLRWLQQEEEERRHQELLQKKKEEEQErlRKAAEAKRLAEQRE 683
Cdd:PTZ00121 1189 KAEELR----------KAEDARKAEAARKAEEERKaeEARKAEDAKKAEAVKKAEEAKKDAEEA--KKAEEERNNEEIRK 1256
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966984660 684 QERREQERQLAEQERRREQERLQAE--RELQEREKALRLQKERLQRELEEKKKKEEQQRLAE--RQLQEEQEKKAKEA 757
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAEEARKADelKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADeaKKKAEEAKKKADAA 1334
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
530-761 |
1.83e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.98 E-value: 1.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 530 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEqkfaQIDEKTEKAKE 609
Cdd:TIGR02168 739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE----ALDELRAELTL 814
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 610 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL-LQKKKEEEQERLRKAAEAKRLAEQREQERRE 688
Cdd:TIGR02168 815 LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEeLEELIEELESELEALLNERASLEEALALLRS 894
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966984660 689 QERQLAEQERRREQERLQAERELQEREKAL---RLQKERLQRELeekkkKEEQQRLAERQLQEEQEKKAKEAAGVS 761
Cdd:TIGR02168 895 ELEELSEELRELESKRSELRRELEELREKLaqlELRLEGLEVRI-----DNLQERLSEEYSLTLEEAEALENKIED 965
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
529-755 |
4.94e-06 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 49.53 E-value: 4.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQK-----FAQIDEK 603
Cdd:pfam13868 59 EEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRqlreeIDEFNEE 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 604 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE--EEQERLRkaaeAKRLAEQ 681
Cdd:pfam13868 139 QAEWKELEKEEEREEDERILEYLKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDekAERDELR----AKLYQEE 214
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966984660 682 REQERREQERQLAeQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 755
Cdd:pfam13868 215 QERKERQKEREEA-EKKARQRQELQQAREEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMK 287
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-757 |
5.05e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 5.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAeqlrRQKVEEDKR----------RRLEEVKLKREERLRKVLQARE--RVEQMK--EEKKKQIE 594
Cdd:PTZ00121 1219 KAEDAKKAEAVKKAEEA----KKDAEEAKKaeeernneeiRKFEEARMAHFARRQAAIKAEEarKADELKkaEEKKKADE 1294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 595 QKFAQIDEKTEKAKE--ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKA 672
Cdd:PTZ00121 1295 AKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE 1374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 673 AEAKRLAEQREQERREQErqlAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEK 752
Cdd:PTZ00121 1375 EAKKKADAAKKKAEEKKK---ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKK 1451
|
....*
gi 966984660 753 KAKEA 757
Cdd:PTZ00121 1452 KAEEA 1456
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
446-769 |
1.53e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 48.81 E-value: 1.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 446 RRKRSYKQAVSELDEEQHLEDEELqpprsktpsspcpsskvVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLR 525
Cdd:pfam02463 198 QELKLKEQAKKALEYYQLKEKLEL-----------------EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEI 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 526 VDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTE 605
Cdd:pfam02463 261 EKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEEL 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 606 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQE 685
Cdd:pfam02463 341 EKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDL 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 686 RREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEqqRLAERQLQEEQEKKAKEAAGVSKALN 765
Cdd:pfam02463 421 LKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSED--LLKETQLVKLQEQLELLLSRQKLEER 498
|
....
gi 966984660 766 VTVD 769
Cdd:pfam02463 499 SQKE 502
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
529-609 |
1.79e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 48.24 E-value: 1.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQ-RLENLRRKEEAEQLRRQKveEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKA 607
Cdd:PRK12704 56 KEALLEaKEEIHKLRNEFEKELRER--RNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEEL 133
|
..
gi 966984660 608 KE 609
Cdd:PRK12704 134 EE 135
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
529-757 |
2.76e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.21 E-value: 2.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKR-----RRLEEVKlkREERLRKVLQARERVEQMKEEKKKQIEQkfAQIDEK 603
Cdd:PTZ00121 1147 KAEDAKRVEIARKAEDARKAEEARKAEDAKkaeaaRKAEEVR--KAEELRKAEDARKAEAARKAEEERKAEE--ARKAED 1222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 604 TEKAKEERLAEEKAKKKAAAKKMEEV---EARRKQE----------------EEARRLRWLQQEEEERRHQELLQKKKEE 664
Cdd:PTZ00121 1223 AKKAEAVKKAEEAKKDAEEAKKAEEErnnEEIRKFEearmahfarrqaaikaEEARKADELKKAEEKKKADEAKKAEEKK 1302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 665 EQERLRKAAEAKRLAEQREQERREQERQLAEQERRREQERLQAE-RELQEREKALRLQKERLQRELEEKKKKEEQQRLAE 743
Cdd:PTZ00121 1303 KADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEaAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA 1382
|
250
....*....|....
gi 966984660 744 RQLQEEQEKKAKEA 757
Cdd:PTZ00121 1383 AKKKAEEKKKADEA 1396
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
427-711 |
2.78e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 47.81 E-value: 2.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 427 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQhLEDEELQPPRSKTPSSPCPSSKVVRPLRTFLHTVQRNQMLMTP 506
Cdd:pfam17380 319 EEAEKARQAEMDRQAAIYAEQERMAMERERELERIR-QEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQE 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 507 TSAPRSVMKSFIKRNTPLRVDPKEKERQRLEnlrrKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVlqarERVEQMK 586
Cdd:pfam17380 398 LEAARKVKILEEERQRKIQQQKVEMEQIRAE----QEEARQREVRRLEEERAREMERVRLEEQERQQQV----ERLRQQE 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 587 EEKKKQieqkfaqideKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERrhqellQKKKEEEQ 666
Cdd:pfam17380 470 EERKRK----------KLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEER------QKAIYEEE 533
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 966984660 667 ERlRKAAEAKRLAEQREQERREQERQLAEQERRREQERLQAEREL 711
Cdd:pfam17380 534 RR-REAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREM 577
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
542-746 |
5.84e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.68 E-value: 5.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 542 KEEAEQLRRQKveeDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIdEKTEKAKEERLAEEKAKKKA 621
Cdd:COG4717 52 EKEADELFKPQ---GRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEEL-EAELEELREELEKLEKLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 622 AAKKMEEVEARRKQEEEARRLRWLQQEEEERRHqeLLQKKKEEEQERLRKAAEAKRLAEQREQERREQERQLAEQERRRE 701
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEERLEELRE--LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQ 205
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 966984660 702 QERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQL 746
Cdd:COG4717 206 QRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARL 250
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
536-756 |
6.44e-05 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 46.48 E-value: 6.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 536 LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE 615
Cdd:pfam15709 325 LEKREQEKASRDRLRAERAEMRRLEVERKRREQEEQRRLQQEQLERAEKMREELELEQQRRFEEIRLRKQRLEEERQRQE 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 616 KAKKKAAAKKMEEVEARRKQEEEARRlrwlqqeeeerrhqELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERQLAE 695
Cdd:pfam15709 405 EEERKQRLQLQAAQERARQQQEEFRR--------------KLQELQRKKQQEEAERAEAEKQRQKELEMQLAEEQKRLME 470
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 966984660 696 QERRREQERLQAERElqEREKALRLQKERLQREleekkkkEEQQRLAERQLQEEQEKKAKE 756
Cdd:pfam15709 471 MAEEERLEYQRQKQE--AEEKARLEAEERRQKE-------EEAARLALEEAMKQAQEQARQ 522
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
540-679 |
1.21e-04 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 45.57 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 540 RRKEEaeqlRRQKVEEDKRRRLEEVKLKREERLRKVLQARErveQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK 619
Cdd:PRK09510 75 KRAEE----QRKKKEQQQAEELQQKQAAEQERLKQLEKERL---AAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAAAKA 147
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 620 KAAAKKMEEVEARRKQEEEARRLrwlqQEEEERRHQELLQKKKEEEQERLRKAAEAKRLA 679
Cdd:PRK09510 148 KAEAEAKRAAAAAKKAAAEAKKK----AEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKA 203
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
524-771 |
1.58e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.82 E-value: 1.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 524 LRVDPKEKERQRLEN----LRRKEEAEQLRRQKVEE------DKRRRLEEVKLKREERLRKVLQARERVEQMKE---EKK 590
Cdd:TIGR02168 232 LRLEELREELEELQEelkeAEEELEELTAELQELEEkleelrLEVSELEEEIEELQKELYALANEISRLEQQKQilrERL 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 591 KQIEQKFAQID---EKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE 667
Cdd:TIGR02168 312 ANLERQLEELEaqlEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 668 RLRKAAEAKRLAEQREQE---RREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAER 744
Cdd:TIGR02168 392 ELQIASLNNEIERLEARLerlEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471
|
250 260
....*....|....*....|....*..
gi 966984660 745 QLQEEQEKKAKEAAGVSKALNVTVDVQ 771
Cdd:TIGR02168 472 EAEQALDAAERELAQLQARLDSLERLQ 498
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
524-642 |
1.73e-04 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 45.33 E-value: 1.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 524 LRVDPKEKERQRLENLRRKEeaeQLRRQKVEEDKRRRLEEVKLKREERLRKVLQ-ARERVEQMKEEKKKQIEQKFAQIDE 602
Cdd:pfam15709 391 LRKQRLEEERQRQEEEERKQ---RLQLQAAQERARQQQEEFRRKLQELQRKKQQeEAERAEAEKQRQKELEMQLAEEQKR 467
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 966984660 603 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 642
Cdd:pfam15709 468 LMEMAEEERLEYQRQKQEAEEKARLEAEERRQKEEEAARL 507
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
529-755 |
2.11e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.35 E-value: 2.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVK---LKREERLRKVLQARERVEQMKEEKKKQiEQKFAQIDEKTE 605
Cdd:pfam02463 691 KEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVqeaQDKINEELKLLKQKIDEEEEEEEKSRL-KKEEKEEEKSEL 769
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 606 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRwlqqeeeerrHQELLQKKKEEEQERLRKAAEAKRLAEQREQE 685
Cdd:pfam02463 770 SLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE----------EELKEEAELLEEEQLLIEQEEKIKEEELEELA 839
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 686 RREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRlaERQLQEEQEKKAK 755
Cdd:pfam02463 840 LELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEK--EKEEKKELEEESQ 907
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
529-760 |
2.66e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.93 E-value: 2.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLeevklkrEERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 608
Cdd:COG1196 373 ELAEAEEELEELAEELLEALRAAAELAAQLEEL-------EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 609 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 688
Cdd:COG1196 446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA 525
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966984660 689 QERQLAEQERRREQERLQAERELQ----EREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGV 760
Cdd:COG1196 526 VAVLIGVEAAYEAALEAALAAALQnivvEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
540-754 |
2.77e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 44.96 E-value: 2.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 540 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKK-QIEQKFAQIDEKTEKAKEERLAEEKAK 618
Cdd:pfam02463 154 RRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQaKKALEYYQLKEKLELEEEYLLYLDYLK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 619 KKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERQLAEQER 698
Cdd:pfam02463 234 LNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDE 313
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 966984660 699 RREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKA 754
Cdd:pfam02463 314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLE 369
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
519-676 |
3.97e-04 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 43.68 E-value: 3.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 519 KRNTPLRVDPKEKERQRLENLRRkeEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERveqmKEEKKKQIEQKFA 598
Cdd:TIGR02794 53 NRIQQQKKPAAKKEQERQKKLEQ--QAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQ----AEEKQKQAEEAKA 126
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966984660 599 QiDEKTEKAKEErlaeekakkkAAAKKMEEVEARRKQEEEARrlrwlqqeeeerrHQELLQKKKEEEQERLRKAAEAK 676
Cdd:TIGR02794 127 K-QAAEAKAKAE----------AEAERKAKEEAAKQAEEEAK-------------AKAAAEAKKKAEEAKKKAEAEAK 180
|
|
| PRK05035 |
PRK05035 |
electron transport complex protein RnfC; Provisional |
541-763 |
4.03e-04 |
|
electron transport complex protein RnfC; Provisional
Pssm-ID: 235334 [Multi-domain] Cd Length: 695 Bit Score: 44.17 E-value: 4.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 541 RKEEAEQLRRQKVE-EDKRRRLEEVKLKREERLRK------------VLQARERVEQMKEEKKKQIEQKFAQIDEKTEKA 607
Cdd:PRK05035 441 IEQEKKKAEEAKARfEARQARLEREKAAREARHKKaaearaakdkdaVAAALARVKAKKAAATQPIVIKAGARPDNSAVI 520
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 608 KEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRwlqqeEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 687
Cdd:PRK05035 521 AAREARKAQARARQAEKQAAAAADPKKAAVAAAIAR-----AKAKKAAQQAANAEAEEEVDPKKAAVAAAIARAKAKKAA 595
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 688 EQERQLAEQERRREQERLQAERELQ-EREKALRLQKERLQRELEEK---------------KKKEEQQRLAERQLQEEQE 751
Cdd:PRK05035 596 QQAASAEPEEQVAEVDPKKAAVAAAiARAKAKKAEQQANAEPEEPVdprkaavaaaiarakARKAAQQQANAEPEEAEDP 675
|
250
....*....|..
gi 966984660 752 KKAKEAAGVSKA 763
Cdd:PRK05035 676 KKAAVAAAIARA 687
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
529-757 |
6.60e-04 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 42.98 E-value: 6.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA---QIDEKTE 605
Cdd:pfam13868 29 AEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQereQMDEIVE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 606 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK---AAEAKRLAEQR 682
Cdd:pfam13868 109 RIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEEREAEreeIEEEKEREIAR 188
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966984660 683 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 757
Cdd:pfam13868 189 LRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAREEQIELKERRLAEEAEREEEEF 263
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
534-665 |
7.49e-04 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 43.28 E-value: 7.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 534 QRLENLRRkeEAEQlrrqkveedKRRRLEEvKLKREERLRKVLQAR-ERVEQMKEEKKKQIEQKFAQIdekTEKAKEERL 612
Cdd:PRK00409 523 ASLEELER--ELEQ---------KAEEAEA-LLKEAEKLKEELEEKkEKLQEEEDKLLEEAEKEAQQA---IKEAKKEAD 587
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 966984660 613 AEEKAKKKAAAKKMEEVeaRRKQEEEARRLrwLQQEEEERRHQELLQKKKEEE 665
Cdd:PRK00409 588 EIIKELRQLQKGGYASV--KAHELIEARKR--LNKANEKKEKKKKKQKEKQEE 636
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
529-763 |
7.77e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.51 E-value: 7.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK------EEKKKQIEQKFAQIDE 602
Cdd:TIGR02168 696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSkeltelEAEIEELEERLEEAEE 775
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 603 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRwlQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQR 682
Cdd:TIGR02168 776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLN--EEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 683 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQ------RELEEKKKKeeqqrlAERQLQEEQEKKAKE 756
Cdd:TIGR02168 854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEelseelRELESKRSE------LRRELEELREKLAQL 927
|
....*..
gi 966984660 757 AAGVSKA 763
Cdd:TIGR02168 928 ELRLEGL 934
|
|
| PTZ00266 |
PTZ00266 |
NIMA-related protein kinase; Provisional |
525-612 |
1.24e-03 |
|
NIMA-related protein kinase; Provisional
Pssm-ID: 173502 [Multi-domain] Cd Length: 1021 Bit Score: 42.80 E-value: 1.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 525 RVDPKEKERQRLE--NLRRKE-EAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 601
Cdd:PTZ00266 429 RVDKDHAERARIEkeNAHRKAlEMKILEKKRIERLEREERERLERERMERIERERLERERLERERLERDRLERDRLDRLE 508
|
90
....*....|..
gi 966984660 602 -EKTEKAKEERL 612
Cdd:PTZ00266 509 rERVDRLERDRL 520
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
529-758 |
1.28e-03 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 41.83 E-value: 1.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVE-------EDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKK---QIEQKFA 598
Cdd:pfam13868 83 EEREQKRQEEYEEKLQEREQMDEIVEriqeedqAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREedeRILEYLK 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 599 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK----KKEEEQERLRKAAE 674
Cdd:pfam13868 163 EKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEReeaeKKARQRQELQQARE 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 675 AKrLAEQREQERREQERQLAEQERRREQERLQAERELQEREKAlRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKA 754
Cdd:pfam13868 243 EQ-IELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKR-RMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320
|
....
gi 966984660 755 KEAA 758
Cdd:pfam13868 321 REEE 324
|
|
| YqiK |
COG2268 |
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]; |
536-679 |
1.46e-03 |
|
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 42.17 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 536 LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK---REERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEER- 611
Cdd:COG2268 186 LDALGRRKIAEIIRDARIAEAEAERETEIAIAqanREAEEAELEQEREIETARIAEAEAELAKKKAEERREAETARAEAe 265
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966984660 612 LAEEKAKKKAAAKKMEEVEARRKQEE----EARRLRWLQQEEEERRHQELLQKKKEEEQERLR-KAAEAKRLA 679
Cdd:COG2268 266 AAYEIAEANAEREVQRQLEIAEREREielqEKEAEREEAELEADVRKPAEAEKQAAEAEAEAEaEAIRAKGLA 338
|
|
| RNase_Y_N |
pfam12072 |
RNase Y N-terminal region; |
542-609 |
1.48e-03 |
|
RNase Y N-terminal region;
Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 40.64 E-value: 1.48e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966984660 542 KEEAEQLRRQKVEEDKRRR-----LEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 609
Cdd:pfam12072 59 KEEIHKLRAEAERELKERRnelqrQERRLLQKEETLDRKDESLEKKEESLEKKEKELEAQQQQLEEKEEELEE 131
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
543-676 |
1.49e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.07 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 543 EEAEQLRRQKVEEDKRrrleEVKLKREErlrKVLQARERVEQMKEEKKKQIEQKFAQID--EKTEKAKEERLAEEKAKKK 620
Cdd:PRK12704 34 KEAEEEAKRILEEAKK----EAEAIKKE---ALLEAKEEIHKLRNEFEKELRERRNELQklEKRLLQKEENLDRKLELLE 106
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 966984660 621 aaakkmeeveaRRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAA-----EAK 676
Cdd:PRK12704 107 -----------KREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISgltaeEAK 156
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
518-765 |
1.67e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 42.36 E-value: 1.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 518 IKRNTPLRVDPKEKERQRLENLRR------KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKK 591
Cdd:PRK03918 170 VIKEIKRRIERLEKFIKRTENIEElikekeKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELES 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 592 qIEQKFAQIDEKTeKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR-----WLQQEEEERRHQELLQKKKEEEQ 666
Cdd:PRK03918 250 -LEGSKRKLEEKI-RELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSefyeeYLDELREIEKRLSRLEEEINGIE 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 667 ERLRKAAEAKRLAEQREQERREQERQLAEQERRREQerLQAERELQEREKALR-----LQKERLQRELEEKKKKEEQQRL 741
Cdd:PRK03918 328 ERIKELEEKEERLEELKKKLKELEKRLEELEERHEL--YEEAKAKKEELERLKkrltgLTPEKLEKELEELEKAKEEIEE 405
|
250 260
....*....|....*....|....
gi 966984660 742 AERQLQEEQEKKAKEAAGVSKALN 765
Cdd:PRK03918 406 EISKITARIGELKKEIKELKKAIE 429
|
|
| ERM_helical |
pfam20492 |
Ezrin/radixin/moesin, alpha-helical domain; The ERM family consists of three closely-related ... |
535-643 |
1.76e-03 |
|
Ezrin/radixin/moesin, alpha-helical domain; The ERM family consists of three closely-related proteins, ezrin, radixin and moesin. Ezrin was first identified as a constituent of microvilli, radixin as a barbed, end-capping actin-modulating protein from isolated junctional fractions, and moesin as a heparin binding protein. A tumour suppressor molecule responsible for neurofibromatosis type 2 (NF2) is highly similar to ERM proteins and has been designated merlin (moesin-ezrin-radixin-like protein). ERM molecules contain 3 domains, an N-terminal globular domain, an extended alpha-helical domain and a charged C-terminal domain (pfam00769). Ezrin, radixin and merlin also contain a polyproline linker region between the helical and C-terminal domains. The N-terminal domain is highly conserved and is also found in merlin, band 4.1 proteins and members of the band 4.1 superfamily, designated the FERM domain. ERM proteins crosslink actin filaments with plasma membranes. They co-localize with CD44 at actin filament plasma membrane interaction sites, associating with CD44 via their N-terminal domains and with actin filaments via their C-terminal domains. This is the alpha-helical domain, which is involved in intramolecular masking of protein-protein interaction sites, regulating the activity of this proteins.
Pssm-ID: 466641 [Multi-domain] Cd Length: 120 Bit Score: 39.13 E-value: 1.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 535 RLENLRRKEEAEQLRRQKVEEDKR-----RRLEEVKLKREERLRKVLQARERVEQmkeeKKKQIEQKFAQIDEKTEKAKE 609
Cdd:pfam20492 1 REEAEREKQELEERLKQYEEETKKaqeelEESEETAEELEEERRQAEEEAERLEQ----KRQEAEEEKERLEESAEMEAE 76
|
90 100 110
....*....|....*....|....*....|....
gi 966984660 610 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 643
Cdd:pfam20492 77 EKEQLEAELAEAQEEIARLEEEVERKEEEARRLQ 110
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
529-610 |
2.00e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.69 E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQ---RLENLRRKEEAEQLRRQKVE------EDKRRRLEEVKLKREERLRKVL-----QARERV-EQMKEEKKKQI 593
Cdd:PRK12704 92 LQKEENldrKLELLEKREEELEKKEKELEqkqqelEKKEEELEELIEEQLQELERISgltaeEAKEILlEKVEEEARHEA 171
|
90
....*....|....*..
gi 966984660 594 eqkFAQIDEKTEKAKEE 610
Cdd:PRK12704 172 ---AVLIKEIEEEAKEE 185
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
427-638 |
2.13e-03 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 42.01 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 427 QQEAKTDQADGPRepPQSarRKRSYKQAVSEldEEQHLEDEELQPPR-----------SKTPSSPCPSSKVVRPLRTFLH 495
Cdd:NF033875 49 QPGTTTVQPDNPD--PQS--GSETPKTAVSE--EATVQKDTTSQPTKveevasekngaEQSSATPNDTTNAQQPTVGAEK 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 496 TVQRNqmlmtPTSAPRSVMKSFikrNTPLRVDPKEKERQRLENLRRKEEAEQLRRqKVEEDKRRRLEEVKLKREERLRKV 575
Cdd:NF033875 123 SAQEQ-----PVVSPETTNEPL---GQPTEVAPAENEANKSTSIPKEFETPDVDK-AVDEAKKDPNITVVEKPAEDLGNV 193
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966984660 576 ----LQARER-VEQMKEEKKKQIEQKFAQIDEKTEKAKEERlaeekakkkaaakkmEEVEARRKQEEE 638
Cdd:NF033875 194 sskdLAAKEKeVDQLQKEQAKKIAQQAAELKAKNEKIAKEN---------------AEIAAKNKAEKE 246
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
529-755 |
2.25e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.88 E-value: 2.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKfAQIDEKTEKAK 608
Cdd:pfam02463 774 KELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALE-LKEEQKLEKLA 852
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 609 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRwlqqeeeERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 688
Cdd:pfam02463 853 EEELERLEEEITKEELLQELLLKEEELEEQKLKDE-------LESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE 925
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 689 QERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKK--------------KKEEQQRLAERQLQEEQEKKA 754
Cdd:pfam02463 926 EAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEelgkvnlmaieefeEKEERYNKDELEKERLEEEKK 1005
|
.
gi 966984660 755 K 755
Cdd:pfam02463 1006 K 1006
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
529-764 |
2.51e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.88 E-value: 2.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLEnlrrkEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKqiEQKFAQIDEKTEKAK 608
Cdd:pfam02463 151 KPERRLEIE-----EEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKK--ALEYYQLKEKLELEE 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 609 EERLAEEKAKKKAAAKKMEEVEARRKQEEEArrlrwlqqeeeerRHQELLQKKKEEEQERLRKAAEAKRlaeqreqerre 688
Cdd:pfam02463 224 EYLLYLDYLKLNEERIDLLQELLRDEQEEIE-------------SSKQEIEKEEEKLAQVLKENKEEEK----------- 279
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966984660 689 qerqlaeqeRRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGVSKAL 764
Cdd:pfam02463 280 ---------EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKE 346
|
|
| DUF4659 |
pfam15558 |
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ... |
514-728 |
3.39e-03 |
|
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.
Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 40.79 E-value: 3.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 514 MKSFIKRNTPLRVDPKEKERQRLENLRRKE-EAEQLRRQKveEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 592
Cdd:pfam15558 86 EKQVIEKESRWREQAEDQENQRQEKLERARqEAEQRKQCQ--EQRLKEKEEELQALREQNSLQLQERLEEACHKRQLKER 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 593 IEQKFAQIDEKTEKAKEERLaeekakkkaaakkMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE-QERLRK 671
Cdd:pfam15558 164 EEQKKVQENNLSELLNHQAR-------------KVLVDCQAKAEELLRRLSLEQSLQRSQENYEQLVEERHRElREKAQK 230
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 966984660 672 AAE----AKRLAEQREQERREQERQLAEQERRREQERLQAERElQEREKALRLQKERLQRE 728
Cdd:pfam15558 231 EEEqfqrAKWRAEEKEEERQEHKEALAELADRKIQQARQVAHK-TVQDKAQRARELNLERE 290
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
403-609 |
3.40e-03 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 41.23 E-value: 3.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 403 DTEIGNST-----PNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAvseldeeqhledeelqpprSKTP 477
Cdd:NF033875 47 DTQPGTTTvqpdnPDPQSGSETPKTAVSEEATVQKDTTSQPTKVEEVASEKNGAEQS-------------------SATP 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 478 SSpcpSSKVVRPLRTFLHTVQRNqmlmtPTSAPRSVMKSFikrNTPLRVDPKEKERQRLENLRRKEEAEQLRRqKVEEDK 557
Cdd:NF033875 108 ND---TTNAQQPTVGAEKSAQEQ-----PVVSPETTNEPL---GQPTEVAPAENEANKSTSIPKEFETPDVDK-AVDEAK 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 966984660 558 RRRLEEVKLKREERLRKV----LQARER-VEQMKEEKKKQIEQKFAQIDEKTEK-AKE 609
Cdd:NF033875 176 KDPNITVVEKPAEDLGNVsskdLAAKEKeVDQLQKEQAKKIAQQAAELKAKNEKiAKE 233
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
529-756 |
3.96e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.20 E-value: 3.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQrLENLRRK-EEAEQLRRQKVE-------------EDKRRRLEEVK--LKREERLRKVLQARERVEQMK-EEKKK 591
Cdd:TIGR02168 196 NELERQ-LKSLERQaEKAERYKELKAElrelelallvlrlEELREELEELQeeLKEAEEELEELTAELQELEEKlEELRL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 592 QIEQKFAQIDEKTEK---------AKEERLAEEKAKKKAAAKKMEEVEARRkQEEEARRLRWLQQEEEERRHQELLQKKK 662
Cdd:TIGR02168 275 EVSELEEEIEELQKElyalaneisRLEQQKQILRERLANLERQLEELEAQL-EELESKLDELAEELAELEEKLEELKEEL 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 663 EEEQERLRKAAEAKRLAEQREQERREQERQLAEQ-ERRREQERLQAER--ELQEREKALRLQKERLQRELEEKKKKEEQQ 739
Cdd:TIGR02168 354 ESLEAELEELEAELEELESRLEELEEQLETLRSKvAQLELQIASLNNEieRLEARLERLEDRRERLQQEIEELLKKLEEA 433
|
250
....*....|....*..
gi 966984660 740 RLAERQLQEEQEKKAKE 756
Cdd:TIGR02168 434 ELKELQAELEELEEELE 450
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
534-756 |
4.33e-03 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 40.62 E-value: 4.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 534 QRLENLRRKEEAEQLRRQKVEEDKrrrLEEVKLKREERLRKVlqARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLA 613
Cdd:pfam02029 69 AKREERRQKRLQEALERQKEFDPT---IADEKESVAERKENN--EEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQEN 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 614 EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERQL 693
Cdd:pfam02029 144 KWSTEVRQAEEEGEEEEDKSEEAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEEEVTKLKVTT 223
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966984660 694 AEQERRREQERLQAERELQEREKALRLQKERLQR-ELEEKKKKEEQQRLAERQLQEEQEKKAKE 756
Cdd:pfam02029 224 KRRQGGLSQSQEREEEAEVFLEAEQKLEELRRRRqEKESEEFEKLRQKQQEAELELEELKKKRE 287
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
525-676 |
4.45e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.52 E-value: 4.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 525 RVDPKEKERQRLENLRRKEEAEQLRRQKVEEdKRRRLEEVKLKREERLRKVLQARERVEQMKEekKKQIEQKFAQIDEKT 604
Cdd:COG4717 72 ELKELEEELKEAEEKEEEYAELQEELEELEE-ELEELEAELEELREELEKLEKLLQLLPLYQE--LEALEAELAELPERL 148
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966984660 605 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL--LQKKKEEEQERLRKAAEAK 676
Cdd:COG4717 149 EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELeeLQQRLAELEEELEEAQEEL 222
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
530-756 |
4.91e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 40.82 E-value: 4.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 530 EKERQRLENLrrKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKfAQIDEKTEKAKE 609
Cdd:PRK03918 227 EKEVKELEEL--KEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEK-AEEYIKLSEFYE 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 610 ERLAEEKAKKKAAAKKMEEVEARRKQ----EEEARRLRWLQQEEEErrhqelLQKKKEEEQERLRKAAEAKRLAEQREQE 685
Cdd:PRK03918 304 EYLDELREIEKRLSRLEEEINGIEERikelEEKEERLEELKKKLKE------LEKRLEELEERHELYEEAKAKKEELERL 377
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966984660 686 RREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQRELEEKKKKEEQQRLAE-------RQLQEEQEKKAKE 756
Cdd:PRK03918 378 KKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgRELTEEHRKELLE 455
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
529-679 |
5.13e-03 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 40.32 E-value: 5.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRK----VLQARERVEQMKEE----------KKKQIE 594
Cdd:pfam15709 364 QQEQLERAEKMREELELEQQRRFEEIRLRKQRLEEERQRQEEEERKqrlqLQAAQERARQQQEEfrrklqelqrKKQQEE 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 595 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRlrwlqqeeeerrhqellqkkKEEEQERLRKAAE 674
Cdd:pfam15709 444 AERAEAEKQRQKELEMQLAEEQKRLMEMAEEERLEYQRQKQEAEEKA--------------------RLEAEERRQKEEE 503
|
....*
gi 966984660 675 AKRLA 679
Cdd:pfam15709 504 AARLA 508
|
|
| MPSS6 |
cd23673 |
mitochondrial 3' processome (MPsome) subunit 6; MPSS6 is a subunit of the mitochondrial 3' ... |
496-562 |
5.50e-03 |
|
mitochondrial 3' processome (MPsome) subunit 6; MPSS6 is a subunit of the mitochondrial 3' processome (MPsome) which is involved in 3'-5' trimming of messenger RNA (mRNA) precursors, in U-tailing of ribosomal RNA (rRNA) and some mRNAs, and in 3'-5' trimming and U-tailing of guide RNAs (gRNAs), during kinetoplast RNA processing. The mitochondrial DNA of Trypanosomatids, known as the kinetoplast DNA (kDNA or mtDNA), consists of a network of dozens of maxicircles and thousands of minicircles concatenated together. Maxicircles are equivalent to other eukaryotic mitochondrial DNAs, while minicircles encode gRNAs involved in U-insertion/deletion editing processes exclusive of Trypanosomatids that produce the maturation of the maxicircle-encoded transcripts. Although most gRNAs are encoded by minicircles, varying numbers of maxicircle-encoded gRNAs have been identified in kinetoplastids species. MPsome subunits include KDSS1 3'-5' exonuclease, RET1 terminal uridyltransferase (TUTase), and several subunits of as yet undefined functions (MPSS1-MPSS6). The maxicircle and minicircle RNAs are transcribed as 3' extended precursors and processed by MPsome-dependent 3'-5' degradation, and in the case of rRNAs and gRNAs also 3' uridylated. Trypanosoma brucei maxicircles encode 9S and 12S rRNAs, two gRNAs, two ribosomal proteins and 16 subunits of respiratory complexes. 12 of the 18 maxicircle genes are present as cryptogenes whose transcripts require U-insertion/deletion editing, mediated by gRNAs, to restore a protein-coding capacity. The MPsome catalyzes the primary uridylation of about 800 nt gRNA precursor transcripts, their processive degradation to a mature size of 40-60 nt, and secondary U-tail addition. MPSS6 is predicted (AlphaFold) to contain a C-terminal oligonucleotide/oligosaccharide binding (OB) fold-like domain.
Pssm-ID: 467890 Cd Length: 243 Bit Score: 39.69 E-value: 5.50e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966984660 496 TVQRNQMLMTPTSAPRSVMKSFIKRNTPLRVDPKEKERQRLE-----NLRR-----KEEAEQLRRQKVEEDKRRRLE 562
Cdd:cd23673 10 TSVHSKQSETPSKVSSKDPFATVSTSVPSNSPSSEDAKIRLEeskqkRLQRqlkdvEEELAALKNESERKTAAVRSA 86
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
511-755 |
5.53e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 40.43 E-value: 5.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 511 RSVMKSFIKRNTPLRVDPKEKERQRLENLRRKEEAEQLRRQKVEE--DKRRRLEEVKLKREE------RLRKVLQARERV 582
Cdd:PRK03918 178 IERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREEleKLEKEVKELEELKEEieelekELESLEGSKRKL 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 583 EQMKEEKKKQIEQKFAQIDEKTEKAKE--ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE-----EEERRHQ 655
Cdd:PRK03918 258 EEKIRELEERIEELKKEIEELEEKVKElkELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGieeriKELEEKE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 656 ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERQLAEQERRREQERLQAERELQEREKAlrlqKERLQRELEEKKKK 735
Cdd:PRK03918 338 ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKA----KEEIEEEISKITAR 413
|
250 260
....*....|....*....|..
gi 966984660 736 EEQ--QRLAERQLQEEQEKKAK 755
Cdd:PRK03918 414 IGElkKEIKELKKAIEELKKAK 435
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
525-609 |
5.92e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 40.41 E-value: 5.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 525 RVDPKEKERQRLENLRRKEEAEQLRRQKVEEdKRRRLEEVKlKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKT 604
Cdd:PRK02224 466 HVETIEEDRERVEELEAELEDLEEEVEEVEE-RLERAEDLV-EAEDRIERLEERREDLEELIAERRETIEEKRERAEELR 543
|
....*
gi 966984660 605 EKAKE 609
Cdd:PRK02224 544 ERAAE 548
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
560-676 |
6.14e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 40.20 E-value: 6.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 560 RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEErlaeekakkkaaaKKMEEVEARRKQEEEA 639
Cdd:PRK00409 524 SLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKE-------------AQQAIKEAKKEADEII 590
|
90 100 110
....*....|....*....|....*....|....*..
gi 966984660 640 RRLRWLQQEEEERRHQELLQkkkeEEQERLRKAAEAK 676
Cdd:PRK00409 591 KELRQLQKGGYASVKAHELI----EARKRLNKANEKK 623
|
|
| DUF4659 |
pfam15558 |
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ... |
529-761 |
6.28e-03 |
|
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.
Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 40.02 E-value: 6.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEAEQLRRQKV---EEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTE 605
Cdd:pfam15558 50 RERRLLLQQSQEQWQAEKEQRKARLgreERRRADRREKQVIEKESRWREQAEDQENQRQEKLERARQEAEQRKQCQEQRL 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 606 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEA-----RRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLae 680
Cdd:pfam15558 130 KEKEEELQALREQNSLQLQERLEEACHKRQLKEReeqkkVQENNLSELLNHQARKVLVDCQAKAEELLRRLSLEQSLQ-- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 681 qreqerreqerqlaeqERRREQERLQAERELQEREKALRlQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGV 760
Cdd:pfam15558 208 ----------------RSQENYEQLVEERHRELREKAQK-EEEQFQRAKWRAEEKEEERQEHKEALAELADRKIQQARQV 270
|
.
gi 966984660 761 S 761
Cdd:pfam15558 271 A 271
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
530-610 |
6.64e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.44 E-value: 6.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 530 EKERQRLENLRRKEEAEQLRR----------QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK---------- 589
Cdd:TIGR02169 332 DKLLAEIEELEREIEEERKRRdklteeyaelKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREInelkreldrl 411
|
90 100
....*....|....*....|....
gi 966984660 590 ---KKQIEQKFAQIDEKTEKAKEE 610
Cdd:TIGR02169 412 qeeLQRLSEELADLNAAIAGIEAK 435
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
543-765 |
7.40e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 40.12 E-value: 7.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 543 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQI-----DEKTEKAKEERLAEEKA 617
Cdd:PTZ00121 1027 EKIEELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKednraDEATEEAFGKAEEAKKT 1106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 618 KKKAAAKKMEEVEARrKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERQLAEQE 697
Cdd:PTZ00121 1107 ETGKAEEARKAEEAK-KKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAE 1185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966984660 698 RRREQERLQAERELQEREKALRLQKERLQRELEEKKKkeeQQRLAERQLQEEQEKKAKEAAGVSKALN 765
Cdd:PTZ00121 1186 EVRKAEELRKAEDARKAEAARKAEEERKAEEARKAED---AKKAEAVKKAEEAKKDAEEAKKAEEERN 1250
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
530-756 |
8.15e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 39.90 E-value: 8.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 530 EKERQRLENLRR-KEEAEQLRRQKVEEDKRRRLEEvKLKREERLRKVLQARERVEQMKEEKKkQIEQKFAQIDEKTEKAK 608
Cdd:COG4913 245 EDAREQIELLEPiRELAERYAAARERLAELEYLRA-ALRLWFAQRRLELLEAELEELRAELA-RLEAELERLEARLDALR 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 609 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRwlqqeeeerrhqellqkkkEEEQERLRKAAEAKRLAEQREqerre 688
Cdd:COG4913 323 EELDELEAQIRGNGGDRLEQLEREIERLERELEER-------------------ERRRARLEALLAALGLPLPAS----- 378
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966984660 689 qerqlaeqerrreqerlqaERELQEREKALRLQKERLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 756
Cdd:COG4913 379 -------------------AEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
|
|
| MAP7 |
pfam05672 |
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ... |
532-668 |
8.33e-03 |
|
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.
Pssm-ID: 461709 [Multi-domain] Cd Length: 153 Bit Score: 37.71 E-value: 8.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 532 ERQRLENLRRKEEaEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEER 611
Cdd:pfam05672 18 EKRRQAREQRERE-EQERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEERQRKAEEEAEEREQREQEEQ 96
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 966984660 612 LAEEKAKKkaaakkmeevEARRKQEEEARRLRwlqqeeeeRRHQELLQKKKEEEQER 668
Cdd:pfam05672 97 ERLQKQKE----------EAEAKAREEAERQR--------QEREKIMQQEEQERLER 135
|
|
| CCDC34 |
pfam13904 |
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ... |
548-675 |
8.77e-03 |
|
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.
Pssm-ID: 464032 [Multi-domain] Cd Length: 221 Bit Score: 38.53 E-value: 8.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 548 LRRQKVEEDKRRRLEE----VKLKREERLRKVL---QARERVEQMKEEKKKQIEQKFAQ-IDEKTEKAKEERLAEEKAKK 619
Cdd:pfam13904 41 ARKLEGLKLERQPLEAyenwLAAKQRQRQKELQaqkEEREKEEQEAELRKRLAKEKYQEwLQRKARQQTKKREESHKQKA 120
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966984660 620 KAAAKKMEEVEARRKQEEEARRL--RWLQQEEEERRHQEL-----LQKKKEEEQERLRKAAEA 675
Cdd:pfam13904 121 AESASKSLAKPERKVSQEEAKEVlqEWERKKLEQQQRKREeeqreQLKKEEEEQERKQLAEKA 183
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
529-758 |
9.97e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 39.67 E-value: 9.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 529 KEKERQRLENLRRKEEaeqlRRQKVEEDKRRRLEEVKLKREER-----LRKVLQARERVEQMKEEKK--KQIEQKFAQID 601
Cdd:TIGR02169 172 KEKALEELEEVEENIE----RLDLIIDEKRQQLERLRREREKAeryqaLLKEKREYEGYELLKEKEAleRQKEAIERQLA 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 602 EKT-EKAK-EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLA 679
Cdd:TIGR02169 248 SLEeELEKlTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966984660 680 EQREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKERLQ-----------------RELEEKKKKEEQQRLA 742
Cdd:TIGR02169 328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEevdkefaetrdelkdyrEKLEKLKREINELKRE 407
|
250
....*....|....*.
gi 966984660 743 ERQLQEEQEKKAKEAA 758
Cdd:TIGR02169 408 LDRLQEELQRLSEELA 423
|
|
| |
