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Conserved domains on  [gi|966982775|ref|XP_014968555|]
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GRIP and coiled-coil domain-containing protein 2 isoform X1 [Macaca mulatta]

Protein Classification

kinesin family protein( domain architecture ID 13531132)

kinesin family protein is a microtubule-dependent molecular motor that plays an important role in intracellular transport and in cell division and has ATPase-containing motor domain; similar to carboxy-terminal kinesins that contains a C-terminal domain responsible for the motor activity (it hydrolyzes ATP and binds microtubules)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Rab_bind pfam16704
Rab binding domain; This coiled-coil domain, found in GRIP and coiled-coil domain-containing ...
1553-1617 1.48e-26

Rab binding domain; This coiled-coil domain, found in GRIP and coiled-coil domain-containing protein 2 and RANBP2-like and GRIP domain-containing protein, has been shown to bind to Rab in GRIP and coiled-coil domain-containing protein 2.


:

Pssm-ID: 435531  Cd Length: 65  Bit Score: 104.05  E-value: 1.48e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966982775  1553 EPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKS 1617
Cdd:pfam16704    1 EPFVWTVEPSKSELTQKLSTTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKS 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
808-1483 3.24e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 3.24e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   808 DKKVFELEKEIKCLQEEsvvqCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEE 887
Cdd:TIGR02168  273 RLEVSELEEEIEELQKE----LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   888 VSQTCNKNEIHNEKEKcsiKEHENLKPLLEQKESELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKE 967
Cdd:TIGR02168  349 LKEELESLEAELEELE---AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEE 425
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   968 KEEKINKIKLVAVKA-----KKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEK 1042
Cdd:TIGR02168  426 LLKKLEEAELKELQAeleelEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFS 505
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1043 ERANNFEHHVEDLTRQLrnsTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEK-------LQK 1115
Cdd:TIGR02168  506 EGVKALLKNQSGLSGIL---GVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRvtflpldSIK 582
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1116 EQKIK----EHATTVNELEELQVQLQKEKKQLQKTMQEL---ELVKKDAQQTTLMNMEIADYERLM-------------- 1174
Cdd:TIGR02168  583 GTEIQgndrEILKNIEGFLGVAKDLVKFDPKLRKALSYLlggVLVVDDLDNALELAKKLRPGYRIVtldgdlvrpggvit 662
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1175 ---KELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIK-------QLLVKTKKELADSKQAE 1244
Cdd:TIGR02168  663 ggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRkeleelsRQISALRKDLARLEAEV 742
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1245 TDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEH---LKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATV 1321
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEieeLEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1322 TSEFESYKVRVHNVLKQ----QKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQMNVSELQTLQSEHDTLLER 1397
Cdd:TIGR02168  823 RERLESLERRIAATERRledlEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1398 HNKMLQETVSKEAELREKlcsiqsenMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSRVEAQL 1477
Cdd:TIGR02168  903 LRELESKRSELRRELEEL--------REKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRL 974

                   ....*.
gi 966982775  1478 FQLKNE 1483
Cdd:TIGR02168  975 KRLENK 980
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
1618-1661 7.66e-12

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


:

Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 61.22  E-value: 7.66e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 966982775  1618 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKL 1661
Cdd:pfam01465    1 GANLEYLKNVLLQFLESKESSERKQLLPVIATLLKFSPEEEQKI 44
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
70-751 2.08e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 2.08e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775    70 TDDIIKALTERLDAILLEKAETEQQCLSLKKENIKMKQEVEDSVTKMEDAHKE---LEQSHINYVKEIENLKNELMAVRA 146
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEisrLEQQKQILRERLANLERQLEELEA 323
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   147 KYSEDKA---NLQKELEEAMNKQLELSEQLKFQNNSEDNVKKLQEEIEKIRPAFEEQILYLQKQLDattdEKKETVTQLQ 223
Cdd:TIGR02168  324 QLEELESkldELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA----QLELQIASLN 399
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   224 NIIEANSQHyqknINSLQEELLQLKAIHQEEVKELMcqiEASAKEHETEINKLNELKENLVKQCEASEKNIQEKYECELE 303
Cdd:TIGR02168  400 NEIERLEAR----LERLEDRRERLQQEIEELLKKLE---EAELKELQAELEELEEELEELQEELERLEEALEELREELEE 472
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   304 NLRKATSNANQDNQMCSLLFQENTFVEQV--VNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFH 381
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLegFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVV 552
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   382 EREDLEFKINELLLAKEEQGCVIEKLKSEL-AGLNKQFCCTVEQHNKEVQSLKE--QHQKEISELNETFLSDS------- 451
Cdd:TIGR02168  553 ENLNAAKKAIAFLKQNELGRVTFLPLDSIKgTEIQGNDREILKNIEGFLGVAKDlvKFDPKLRKALSYLLGGVlvvddld 632
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   452 ------------------EKEKLTLMFEIQGLKEQCDNLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQ 513
Cdd:TIGR02168  633 nalelakklrpgyrivtlDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE 712
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   514 QqasdVHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQQElvpELENTIKNLEEKNGVYLLSLSQRDTMLKELEAKIN 593
Cdd:TIGR02168  713 E----LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA---QLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   594 SLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLM 673
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   674 VQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKNDVI-----LKEHITELEKKLQLMVEERDNLNKLL 748
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRreleeLREKLAQLELRLEGLEVRIDNLQERL 945

                   ...
gi 966982775   749 ENE 751
Cdd:TIGR02168  946 SEE 948
 
Name Accession Description Interval E-value
Rab_bind pfam16704
Rab binding domain; This coiled-coil domain, found in GRIP and coiled-coil domain-containing ...
1553-1617 1.48e-26

Rab binding domain; This coiled-coil domain, found in GRIP and coiled-coil domain-containing protein 2 and RANBP2-like and GRIP domain-containing protein, has been shown to bind to Rab in GRIP and coiled-coil domain-containing protein 2.


Pssm-ID: 435531  Cd Length: 65  Bit Score: 104.05  E-value: 1.48e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966982775  1553 EPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKS 1617
Cdd:pfam16704    1 EPFVWTVEPSKSELTQKLSTTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKS 65
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
808-1483 3.24e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 3.24e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   808 DKKVFELEKEIKCLQEEsvvqCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEE 887
Cdd:TIGR02168  273 RLEVSELEEEIEELQKE----LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   888 VSQTCNKNEIHNEKEKcsiKEHENLKPLLEQKESELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKE 967
Cdd:TIGR02168  349 LKEELESLEAELEELE---AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEE 425
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   968 KEEKINKIKLVAVKA-----KKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEK 1042
Cdd:TIGR02168  426 LLKKLEEAELKELQAeleelEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFS 505
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1043 ERANNFEHHVEDLTRQLrnsTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEK-------LQK 1115
Cdd:TIGR02168  506 EGVKALLKNQSGLSGIL---GVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRvtflpldSIK 582
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1116 EQKIK----EHATTVNELEELQVQLQKEKKQLQKTMQEL---ELVKKDAQQTTLMNMEIADYERLM-------------- 1174
Cdd:TIGR02168  583 GTEIQgndrEILKNIEGFLGVAKDLVKFDPKLRKALSYLlggVLVVDDLDNALELAKKLRPGYRIVtldgdlvrpggvit 662
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1175 ---KELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIK-------QLLVKTKKELADSKQAE 1244
Cdd:TIGR02168  663 ggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRkeleelsRQISALRKDLARLEAEV 742
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1245 TDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEH---LKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATV 1321
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEieeLEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1322 TSEFESYKVRVHNVLKQ----QKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQMNVSELQTLQSEHDTLLER 1397
Cdd:TIGR02168  823 RERLESLERRIAATERRledlEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1398 HNKMLQETVSKEAELREKlcsiqsenMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSRVEAQL 1477
Cdd:TIGR02168  903 LRELESKRSELRRELEEL--------REKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRL 974

                   ....*.
gi 966982775  1478 FQLKNE 1483
Cdd:TIGR02168  975 KRLENK 980
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
1618-1661 7.66e-12

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 61.22  E-value: 7.66e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 966982775  1618 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKL 1661
Cdd:pfam01465    1 GANLEYLKNVLLQFLESKESSERKQLLPVIATLLKFSPEEEQKI 44
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
70-751 2.08e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 2.08e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775    70 TDDIIKALTERLDAILLEKAETEQQCLSLKKENIKMKQEVEDSVTKMEDAHKE---LEQSHINYVKEIENLKNELMAVRA 146
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEisrLEQQKQILRERLANLERQLEELEA 323
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   147 KYSEDKA---NLQKELEEAMNKQLELSEQLKFQNNSEDNVKKLQEEIEKIRPAFEEQILYLQKQLDattdEKKETVTQLQ 223
Cdd:TIGR02168  324 QLEELESkldELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA----QLELQIASLN 399
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   224 NIIEANSQHyqknINSLQEELLQLKAIHQEEVKELMcqiEASAKEHETEINKLNELKENLVKQCEASEKNIQEKYECELE 303
Cdd:TIGR02168  400 NEIERLEAR----LERLEDRRERLQQEIEELLKKLE---EAELKELQAELEELEEELEELQEELERLEEALEELREELEE 472
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   304 NLRKATSNANQDNQMCSLLFQENTFVEQV--VNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFH 381
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLegFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVV 552
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   382 EREDLEFKINELLLAKEEQGCVIEKLKSEL-AGLNKQFCCTVEQHNKEVQSLKE--QHQKEISELNETFLSDS------- 451
Cdd:TIGR02168  553 ENLNAAKKAIAFLKQNELGRVTFLPLDSIKgTEIQGNDREILKNIEGFLGVAKDlvKFDPKLRKALSYLLGGVlvvddld 632
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   452 ------------------EKEKLTLMFEIQGLKEQCDNLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQ 513
Cdd:TIGR02168  633 nalelakklrpgyrivtlDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE 712
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   514 QqasdVHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQQElvpELENTIKNLEEKNGVYLLSLSQRDTMLKELEAKIN 593
Cdd:TIGR02168  713 E----LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA---QLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   594 SLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLM 673
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   674 VQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKNDVI-----LKEHITELEKKLQLMVEERDNLNKLL 748
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRreleeLREKLAQLELRLEGLEVRIDNLQERL 945

                   ...
gi 966982775   749 ENE 751
Cdd:TIGR02168  946 SEE 948
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
115-712 2.80e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.47  E-value: 2.80e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  115 KMEDAHKELEQSHINYVKEIENLKNELMAvRAKYSEDKANLQKELEEAMNKQLELSEQLKFQNNSEDNVKKLQEEIEKIR 194
Cdd:PRK03918  159 DYENAYKNLGEVIKEIKRRIERLEKFIKR-TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELK 237
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  195 PAFEEqilyLQKQLDATTDEKKEtvtqlqniIEANSQHYQKNINSLQEELLQLKaihqEEVKELmcqieASAKEHETEIN 274
Cdd:PRK03918  238 EEIEE----LEKELESLEGSKRK--------LEEKIRELEERIEELKKEIEELE----EKVKEL-----KELKEKAEEYI 296
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  275 KLNELKENLVKQCEASEKNIqEKYECELENLRKATSNANQDNqmcsllfqentfveqvvnEKVKHLEDTLKELESQHSIL 354
Cdd:PRK03918  297 KLSEFYEEYLDELREIEKRL-SRLEEEINGIEERIKELEEKE------------------ERLEELKKKLKELEKRLEEL 357
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  355 KDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQfcctVEQHNKEVQSLK- 433
Cdd:PRK03918  358 EERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE----IKELKKAIEELKk 433
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  434 -------------EQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCDNLQQE--KQEAILNYESLREIMEILQTELG 498
Cdd:PRK03918  434 akgkcpvcgreltEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVlkKESELIKLKELAEQLKELEEKLK 513
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  499 EsagkisqefesmkqqqaSDVHELQQKLRtaftEKDALLETVNHLQGENEKLLSQQELVPELENTIKNLEEKNGVYLLSL 578
Cdd:PRK03918  514 K-----------------YNLEELEKKAE----EYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEEL 572
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  579 SQRDTMLKELEAKINSLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEEt 658
Cdd:PRK03918  573 AELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE- 651
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....
gi 966982775  659 lKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLE 712
Cdd:PRK03918  652 -LEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
1619-1663 6.29e-10

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 56.07  E-value: 6.29e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*
gi 966982775   1619 ANLEYLKNVLLQFIFLKPgSERERLLPVINTMLQLSPEEKGKLAA 1663
Cdd:smart00755    2 ANFEYLKNVLLQFLTLRE-SERETLLPVISTVLQLSPEEMQKLLE 45
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
92-734 9.72e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 60.52  E-value: 9.72e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775    92 EQQCLSLKKENIKMK---QEVEDSVTKMEDAHKELEQSHINYVKEIENLKNELMAVRAkysedkanLQKELEEAMNKQLE 168
Cdd:pfam15921  102 EKQKFYLRQSVIDLQtklQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKC--------LKEDMLEDSNTQIE 173
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   169 lseQLKFQNNSEDNVkklQEEIEKIRPAFEE---QILYLQKQLDATTDEKKET-VTQLQNIIEANSQHYQKNINSLQEEL 244
Cdd:pfam15921  174 ---QLRKMMLSHEGV---LQEIRSILVDFEEasgKKIYEHDSMSTMHFRSLGSaISKILRELDTEISYLKGRIFPVEDQL 247
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   245 LQLKAIHQEEVKELMCQ----IEASAKEHETEINKLNELKENLVKQCEAseknIQEKYECELENLRKATSNanqdnQMCS 320
Cdd:pfam15921  248 EALKSESQNKIELLLQQhqdrIEQLISEHEVEITGLTEKASSARSQANS----IQSQLEIIQEQARNQNSM-----YMRQ 318
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   321 LLFQENTF--VEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKE 398
Cdd:pfam15921  319 LSDLESTVsqLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKE 398
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   399 E----------QGCVIEKLKSELAGLN---KQFCCTVEQHNKEVQSLKEQHQKEISELNETFLSDSekeklTLMFEIQGL 465
Cdd:pfam15921  399 QnkrlwdrdtgNSITIDHLRRELDDRNmevQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVS-----SLTAQLEST 473
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   466 KEQCDNLQQEKQEAILNYESLREIMEILQTELGESAGKI---SQEFESMKQQQASDVHELQ----------------QKL 526
Cdd:pfam15921  474 KEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIeatNAEITKLRSRVDLKLQELQhlknegdhlrnvqtecEAL 553
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   527 RTAFTEKDALLETVNHLQGENEKLLSQ--------QELVPELENTIKNLEEKNGVYLLSLSQRDTMLKELEAKINSL--- 595
Cdd:pfam15921  554 KLQMAEKDKVIEILRQQIENMTQLVGQhgrtagamQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLele 633
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   596 ------------------TEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQ--------YNSELEQKVN 649
Cdd:pfam15921  634 kvklvnagserlravkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNklkmqlksAQSELEQTRN 713
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   650 ELTG-------------GLEETLKEK----DQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLE 712
Cdd:pfam15921  714 TLKSmegsdghamkvamGMQKQITAKrgqiDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELE 793
                          730       740
                   ....*....|....*....|..
gi 966982775   713 VFLSQKNDviLKEHITELEKKL 734
Cdd:pfam15921  794 VLRSQERR--LKEKVANMEVAL 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
619-1222 1.33e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 1.33e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  619 KCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLmvqmkvlSEDKEVLSAEVKSLYEENN 698
Cdd:COG1196   219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL-------RLELEELELELEEAQAEEY 291
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  699 KLSSEKKQLSRDLEVFLSQKNDviLKEHITELEKKLQLMVEERDNLNKLLENEQVQKLFVKTQLygflkdMGSEVSEDGE 778
Cdd:COG1196   292 ELLAELARLEQDIARLEERRRE--LEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL------EEAEAELAEA 363
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  779 EKDVVNILQAVSESLAKINEEKcNLVFQCDKKVFELEKEIKCLQEesvvQCEELKSLLRDYEQEKVLLRKELEEIQSEKE 858
Cdd:COG1196   364 EEALLEAEAELAEAEEELEELA-EELLEALRAAAELAAQLEELEE----AEEALLERLERLEEELEELEEALAELEEEEE 438
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  859 ALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCNKNEIHNEKEKCSIKEHENLKPLLEQKEsELRDTRAELILLKDSLA 938
Cdd:COG1196   439 EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE-ADYEGFLEGVKAALLLA 517
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  939 KSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIKLVAVKAKKELDSSRKETQTVREELESLRSEKDQLSASMRDLI 1018
Cdd:COG1196   518 GLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAI 597
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1019 QAAESYKNLLLEYEKQSEQL--------DVEKERANNFEHHVEDLTRQLRNSTLQCEKINSDNEDLL-ARIETLQSNAKL 1089
Cdd:COG1196   598 GAAVDLVASDLREADARYYVlgdtllgrTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGgSRRELLAALLEA 677
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1090 LEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIAD 1169
Cdd:COG1196   678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966982775 1170 YERLMKELNQKLSNKNNKIEDLE----------QEIKIQKQ----KQETLQEEITSLQSSVQQYEEK 1222
Cdd:COG1196   758 EPPDLEELERELERLEREIEALGpvnllaieeyEELEERYDflseQREDLEEARETLEEAIEEIDRE 824
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
85-1481 1.75e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 60.07  E-value: 1.75e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775    85 LLEKAETEQQCLSLKKENIKMKQEVEDSVTKMEDAHKELEQSH---INYVKE--IENLKNELMAVRAKYSEDKAN----- 154
Cdd:TIGR01612  326 LIKILESEGEQGHIINKLIFLEKEFEDTIHKSDIYKDECLSNHlfmEDYLKDdkISPYYYEFLEEIKKIAKQRAIffyna 405
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   155 --------LQKELEEAMNKQLELSEQLKFQNNSEDNVKKLQEEIEKI-RPAFEEQILYLQKQLDATTDEkketvtqlqni 225
Cdd:TIGR01612  406 kklkhleiLYKHQEDILNNFHKTIERLIFEKPDPNNNNIFKDDFDEFnKPIPKSKLKALEKRFFEIFEE----------- 474
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   226 iEANSQHYQKNI--NSLQEELLQLKAIHQEEVKELMCQIEASAKEHETEINK-LNELKENLVKQCEAS-EKNIQEKYECe 301
Cdd:TIGR01612  475 -EWGSYDIKKDIdeNSKQDNTVKLILMRMKDFKDIIDFMELYKPDEVPSKNIiGFDIDQNIKAKLYKEiEAGLKESYEL- 552
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   302 LENLRKatsnanqdnqmcsLLFQENTFVEQVvNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFH 381
Cdd:TIGR01612  553 AKNWKK-------------LIHEIKKELEEE-NEDSIHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNISDKNEY 618
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   382 EREDLEFK---------INEllLAKEEQGCVIEKLKSE-------LAGLNKQFCCTVEQHNKEVQSLKEQHQKEISElNE 445
Cdd:TIGR01612  619 IKKAIDLKkiiennnayIDE--LAKISPYQVPEHLKNKdkiystiKSELSKIYEDDIDALYNELSSIVKENAIDNTE-DK 695
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   446 TFLS------DSEKEKLTLMfEIQGLKEQCDNLQQEKQEAIlnyESLREIMEILQTELGESAGKISQEFESMKQQQASDV 519
Cdd:TIGR01612  696 AKLDdlkskiDKEYDKIQNM-ETATVELHLSNIENKKNELL---DIIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKI 771
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   520 HELQQKLRTAFTEKDALLETVNHLQgenekllSQQELVPELENTIKNLEEKNGVYLLSLSQRDtmlKELEAKINSLTEEK 599
Cdd:TIGR01612  772 NDYAKEKDELNKYKSKISEIKNHYN-------DQINIDNIKDEDAKQNYDKSKEYIKTISIKE---DEIFKIINEMKFMK 841
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   600 DDFINKLkNSYEEMDNFHK-KCEREERLILELGKKV--EQTTQYNSELEQKVNELTGGLEET---LKEKDQNDQKLEKLM 673
Cdd:TIGR01612  842 DDFLNKV-DKFINFENNCKeKIDSEHEQFAELTNKIkaEISDDKLNDYEKKFNDSKSLINEInksIEEEYQNINTLKKVD 920
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   674 VQMKVLSEDKEvlsaEVKSLYEENNKLSSEKKQ------LSRDLEVFLSQKNDVILKEHITELEK---KLQLMVEERDN- 743
Cdd:TIGR01612  921 EYIKICENTKE----SIEKFHNKQNILKEILNKnidtikESNLIEKSYKDKFDNTLIDKINELDKafkDASLNDYEAKNn 996
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   744 -----LNKLLENEQVQKLFVKTQLYGFLKDMGSEVSEDGEE--KDVVNILQAVSESLAKINEEKCNLVfqcDKKVFELEK 816
Cdd:TIGR01612  997 elikyFNDLKANLGKNKENMLYHQFDEKEKATNDIEQKIEDanKNIPNIEIAIHTSIYNIIDEIEKEI---GKNIELLNK 1073
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   817 EIKCLQEESVVQCEELKSLLRDY------EQEKVLLRKELEEIQSEKEALQ-------SDLLEMKNANEKTRLENQNLLI 883
Cdd:TIGR01612 1074 EILEEAEINITNFNEIKEKLKHYnfddfgKEENIKYADEINKIKDDIKNLDqkidhhiKALEEIKKKSENYIDEIKAQIN 1153
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   884 QVEEVSQTCnkneIHNEKEKCSIKEHENLKPLLEQKE------SELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEK 957
Cdd:TIGR01612 1154 DLEDVADKA----ISNDDPEEIEKKIENIVTKIDKKKniydeiKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLE 1229
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   958 LENLEKEGKEKEEKINKIKLvavkakKELDSSRKETQtvreELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQ 1037
Cdd:TIGR01612 1230 KIDEEKKKSEHMIKAMEAYI------EDLDEIKEKSP----EIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDEN 1299
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1038 LDVEKERA------NNFEHHVEDLTRQLRNSTLQCEKINSDNEDLLARIETLQSnakllevqILEVQRAKAMVDKELEAE 1111
Cdd:TIGR01612 1300 ISDIREKSlkiiedFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYN--------ILKLNKIKKIIDEVKEYT 1371
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1112 KlqkeqKIKEHATTVNEleelqvQLQKEKKQLQKTMQELELVK-KDAQQTTLMNMEIadyerlmKELNQKLSNKNNKIED 1190
Cdd:TIGR01612 1372 K-----EIEENNKNIKD------ELDKSEKLIKKIKDDINLEEcKSKIESTLDDKDI-------DECIKKIKELKNHILS 1433
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1191 LEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNtkikQLLVKTKKEladskQAETDHLILQASLKGELEASQQqvevYKI 1270
Cdd:TIGR01612 1434 EESNIDTYFKNADENNENVLLLFKNIEMADNKS----QHILKIKKD-----NATNDHDFNINELKEHIDKSKG----CKD 1500
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1271 QlaeitSEKHkihehlKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTSEFESYKVRvhNVLKQQKNKSMSQAETE 1350
Cdd:TIGR01612 1501 E-----ADKN------AKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIII--KEIKDAHKKFILEAEKS 1567
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1351 GAKQEREHLEMLIDQLKIKLQDSQN----NLQMNVSELQTLQSEHDTLLERHNKMLQETVSKEAELREklCSIQSENMMM 1426
Cdd:TIGR01612 1568 EQKIKEIKKEKFRIEDDAAKNDKSNkaaiDIQLSLENFENKFLKISDIKKKINDCLKETESIEKKISS--FSIDSQDTEL 1645
                         1450      1460      1470      1480      1490
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 966982775  1427 KsehtQTVSQLTSQNEVLRnSFRDQVRHLqEEHRKTVETLQQQLSRVEAQLFQLK 1481
Cdd:TIGR01612 1646 K----ENGDNLNSLQEFLE-SLKDQKKNI-EDKKKELDELDSEIEKIEIDVDQHK 1694
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
1101-1472 2.71e-07

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 55.83  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1101 KAMVDKELEAEKLQKEQKIKEHATTVNELEELQVqlqkekkqLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQK 1180
Cdd:PRK10929   16 GAYAATAPDEKQITQELEQAKAAKTPAQAEIVEA--------LQSALNWLEERKGSLERAKQYQQVIDNFPKLSAELRQQ 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1181 LSNKNNKIEDLEQEIKIQKQKQETLQeeITSlqssvqqyeekntkikQLLvktkkELADSKQAETDHLILQASLKGELea 1260
Cdd:PRK10929   88 LNNERDEPRSVPPNMSTDALEQEILQ--VSS----------------QLL-----EKSRQAQQEQDRAREISDSLSQL-- 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1261 SQQQVEVYKiQLAEITSeKHKIHEHLKTSAEQHQRtlsayrqrvTALQEESRAAKAeqatVTSEFESYKVRVHNvlKQQk 1340
Cdd:PRK10929  143 PQQQTEARR-QLNEIER-RLQTLGTPNTPLAQAQL---------TALQAESAALKA----LVDELELAQLSANN--RQE- 204
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1341 nksMSQAETEGAKQEREHLEMLIDQLKIKLqdsqNNLQMNVSElQTLqsEHDTLLERHNKMLQETVSKEAELREKLCSI- 1419
Cdd:PRK10929  205 ---LARLRSELAKKRSQQLDAYLQALRNQL----NSQRQREAE-RAL--ESTELLAEQSGDLPKSIVAQFKINRELSQAl 274
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 966982775 1420 --QSENM-MMKSEHTQTVSQLTSQNEVLrNSFRDQVRHLQEEhrkTV--ETLQQQLSR 1472
Cdd:PRK10929  275 nqQAQRMdLIASQQRQAASQTLQVRQAL-NTLREQSQWLGVS---NAlgEALRAQVAR 328
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
627-1416 2.73e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.67  E-value: 2.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   627 ILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKL--SSEK 704
Cdd:pfam02463  137 FLVQGGKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALeyYQLK 216
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   705 KQLSRDLEVFLSQKNDVILKEHITELEKKLQLMVEERDNLNKLLENEQVQKLFVKTQLYGFLKDMGSEVSEDGEEKDVVN 784
Cdd:pfam02463  217 EKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEE 296
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   785 ILQAVSESLAKINEEKCNLVFQCDKKVFELEKEIKCLQEESVVQCEELKSLLRDYEQEKV----LLRKELEEIQSEKEAL 860
Cdd:pfam02463  297 ELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEeeeeLEKLQEKLEQLEEELL 376
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   861 QSDLLEMKNANEKTRLENQNLLIQVEEVSQTCNKNEIHNEKEKCSIKEHENLKPLLEQKESELRDTRAELILLKDSLAKS 940
Cdd:pfam02463  377 AKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQ 456
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   941 PSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIKLVAVKAKKELDSSRKETQTVREELESLRSEK-DQLSASMRDLIQ 1019
Cdd:pfam02463  457 ELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRiISAHGRLGDLGV 536
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1020 AAESYKNL-LLEYEKQSEQLDVEKERANNFEHHVEDLTRQLRNSTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQ 1098
Cdd:pfam02463  537 AVENYKVAiSTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEAD 616
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1099 RAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELN 1178
Cdd:pfam02463  617 EDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1179 QKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGEL 1258
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1259 EASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTSEFESYKVRVHNVLKQ 1338
Cdd:pfam02463  777 AEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEEL 856
                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966982775  1339 QKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQMNVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKL 1416
Cdd:pfam02463  857 ERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE 934
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
74-357 1.43e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.94  E-value: 1.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   74 IKALTERLDAILLEKAETEQQCLSLKKEnikmKQEVEDSVTKMEDAHKELEQSHINYVKEIENLKNELmavrAKYSEDKA 153
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAE----LAELEAELEELRLELEELELELEEAQAEEYELLAEL----ARLEQDIA 305
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  154 NLQKELEEAMNKQLELSEQLKFQNNSEDNVKKLQEEIEKIRPAFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHY 233
Cdd:COG1196   306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  234 QKNINSLQEELLQLKAIHQEEVKELmcQIEASAKEHETEINKLNELKENLVKQCEASEKNIQEKYECELENLRKATSNAN 313
Cdd:COG1196   386 EELLEALRAAAELAAQLEELEEAEE--ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 966982775  314 QDnqmcsllfQENTFVEQVVNEKVKHLEDTLKELESQHSILKDE 357
Cdd:COG1196   464 LL--------AELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
657-894 1.83e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 49.54  E-value: 1.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  657 ETLKEKDQNDQ---KLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQkndvILKEhITELEKK 733
Cdd:PRK05771   34 EDLKEELSNERlrkLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEK----IEKE-IKELEEE 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  734 LQLMVEERDNLNKLLE--------NEQVQKLFVKTQLYGFLkdmgSEVSEDGEEKDVVNILQAVSEsLAKINEEKCNLVF 805
Cdd:PRK05771  109 ISELENEIKELEQEIErlepwgnfDLDLSLLLGFKYVSVFV----GTVPEDKLEELKLESDVENVE-YISTDKGYVYVVV 183
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  806 QCDKKVF-ELEKEIKCL--QEESVVQCEELKSLLRDYEQEkvllrkeLEEIQSEKEALQSDLLEMKNANEKTRLENQNLL 882
Cdd:PRK05771  184 VVLKELSdEVEEELKKLgfERLELEEEGTPSELIREIKEE-------LEEIEKERESLLEELKELAKKYLEELLALYEYL 256
                         250
                  ....*....|..
gi 966982775  883 IQVEEVSQTCNK 894
Cdd:PRK05771  257 EIELERAEALSK 268
 
Name Accession Description Interval E-value
Rab_bind pfam16704
Rab binding domain; This coiled-coil domain, found in GRIP and coiled-coil domain-containing ...
1553-1617 1.48e-26

Rab binding domain; This coiled-coil domain, found in GRIP and coiled-coil domain-containing protein 2 and RANBP2-like and GRIP domain-containing protein, has been shown to bind to Rab in GRIP and coiled-coil domain-containing protein 2.


Pssm-ID: 435531  Cd Length: 65  Bit Score: 104.05  E-value: 1.48e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966982775  1553 EPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKS 1617
Cdd:pfam16704    1 EPFVWTVEPSKSELTQKLSTTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKS 65
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
808-1483 3.24e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 3.24e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   808 DKKVFELEKEIKCLQEEsvvqCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEE 887
Cdd:TIGR02168  273 RLEVSELEEEIEELQKE----LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   888 VSQTCNKNEIHNEKEKcsiKEHENLKPLLEQKESELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKE 967
Cdd:TIGR02168  349 LKEELESLEAELEELE---AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEE 425
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   968 KEEKINKIKLVAVKA-----KKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEK 1042
Cdd:TIGR02168  426 LLKKLEEAELKELQAeleelEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFS 505
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1043 ERANNFEHHVEDLTRQLrnsTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEK-------LQK 1115
Cdd:TIGR02168  506 EGVKALLKNQSGLSGIL---GVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRvtflpldSIK 582
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1116 EQKIK----EHATTVNELEELQVQLQKEKKQLQKTMQEL---ELVKKDAQQTTLMNMEIADYERLM-------------- 1174
Cdd:TIGR02168  583 GTEIQgndrEILKNIEGFLGVAKDLVKFDPKLRKALSYLlggVLVVDDLDNALELAKKLRPGYRIVtldgdlvrpggvit 662
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1175 ---KELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIK-------QLLVKTKKELADSKQAE 1244
Cdd:TIGR02168  663 ggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRkeleelsRQISALRKDLARLEAEV 742
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1245 TDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEH---LKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATV 1321
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEieeLEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1322 TSEFESYKVRVHNVLKQ----QKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQMNVSELQTLQSEHDTLLER 1397
Cdd:TIGR02168  823 RERLESLERRIAATERRledlEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1398 HNKMLQETVSKEAELREKlcsiqsenMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSRVEAQL 1477
Cdd:TIGR02168  903 LRELESKRSELRRELEEL--------REKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRL 974

                   ....*.
gi 966982775  1478 FQLKNE 1483
Cdd:TIGR02168  975 KRLENK 980
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
433-1226 1.82e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 1.82e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   433 KEQHQKEISELNETfLSDSEKEKLTLMFEIQGLKEQCDNLQQEKQEailnyesLREIMEILQTELGESAGKISqEFESMK 512
Cdd:TIGR02168  234 LEELREELEELQEE-LKEAEEELEELTAELQELEEKLEELRLEVSE-------LEEEIEELQKELYALANEIS-RLEQQK 304
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   513 QQQASDVHELQQKLRTAFTEKDALLETVNHLQgenEKLLSQQELVPELENTIKNLEEKngvyllsLSQRDTMLKELEAKI 592
Cdd:TIGR02168  305 QILRERLANLERQLEELEAQLEELESKLDELA---EELAELEEKLEELKEELESLEAE-------LEELEAELEELESRL 374
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   593 NSLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQK-----VNELTGGLEETLKEKDQNDQ 667
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKleeaeLKELQAELEELEEELEELQE 454
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   668 KLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKNDVI---------------LKEHItELEK 732
Cdd:TIGR02168  455 ELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKallknqsglsgilgvLSELI-SVDE 533
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   733 KLQLMVEE--RDNLNKLL-ENEQVQKLFVktqlyGFLKDmgsevsedgEEKDVVNILQAVSESLAKINEEKCNLVFQCDK 809
Cdd:TIGR02168  534 GYEAAIEAalGGRLQAVVvENLNAAKKAI-----AFLKQ---------NELGRVTFLPLDSIKGTEIQGNDREILKNIEG 599
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   810 KVFELEKEIKCLQEES---------VVQCEELKSLLRDY----------------------------EQEKVLL--RKEL 850
Cdd:TIGR02168  600 FLGVAKDLVKFDPKLRkalsyllggVLVVDDLDNALELAkklrpgyrivtldgdlvrpggvitggsaKTNSSILerRREI 679
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   851 EEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEvsqtcnkneihnekekcsikehenLKPLLEQKESELRDTRAEL 930
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQ------------------------LRKELEELSRQISALRKDL 735
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   931 ILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIKLVAVKAKKELDSSRKETQTVREELESLRSEKDQL 1010
Cdd:TIGR02168  736 ARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1011 SASMRDLIQAAESYKNLLLEYEKQSEQLDVEKERAnnfEHHVEDLTRQLRNSTLQCEKINSDNEDLLARIETLQSNAKLL 1090
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATERRLEDLEEQIEEL---SEDIESLAAEIEELEELIEELESELEALLNERASLEEALALL 892
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1091 EVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQL-QKTMQELELVKKDAQQTTlmnMEIAD 1169
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLsEEYSLTLEEAEALENKIE---DDEEE 969
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 966982775  1170 YERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKI 1226
Cdd:TIGR02168  970 ARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
451-1214 9.76e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 9.76e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   451 SEKEKLTLMFEIQGLKEQCDNLQQEKQEAilnyeslREIMEILQTELGESAGKISqEFESMKQQQASDVHELQQKLRTAF 530
Cdd:TIGR02168  223 RELELALLVLRLEELREELEELQEELKEA-------EEELEELTAELQELEEKLE-ELRLEVSELEEEIEELQKELYALA 294
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   531 TEKDALLETVNHLQGENEKLLSQQElvpELENTIKNLEEKNGVYLLSLSQRDTMLKELEAKINSLTEEKDDFINKLKNSY 610
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLE---ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   611 EEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLmvQMKVLSEDKEVLSAEV 690
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEEL 449
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   691 KSLYEENNKLSSEKKQLSRDLEVflsqkndviLKEHITELEKKLQLMVEERDNLNKLLENEQ------VQKLFVKTQLYG 764
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEE---------AEQALDAAERELAQLQARLDSLERLQENLEgfsegvKALLKNQSGLSG 520
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   765 FLKDMGSEVS-EDGEEKDVVNILQAVSESLAKINEEKCNLVFQCDKKVFELEKEIKCLQEESVVQCEELKSLLRDYEQEK 843
Cdd:TIGR02168  521 ILGVLSELISvDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGF 600
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   844 VLLRKELEEIQSEKEALQSDLL-------EMKNANEKTRLENQNLLIQVEEvSQTCNKNEIhnekekcSIKEHENLKPLL 916
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYLLggvlvvdDLDNALELAKKLRPGYRIVTLD-GDLVRPGGV-------ITGGSAKTNSSI 672
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   917 EQKESELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKiklvavkAKKELDSSRKETQTV 996
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA-------LRKDLARLEAEVEQL 745
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   997 REELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEkerannfehhVEDLTRQLRNSTLQCEKINSDNEDL 1076
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ----------IEQLKEELKALREALDELRAELTLL 815
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1077 LARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKD 1156
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE 895
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 966982775  1157 AQQttlMNMEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQS 1214
Cdd:TIGR02168  896 LEE---LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
1618-1661 7.66e-12

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 61.22  E-value: 7.66e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 966982775  1618 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKL 1661
Cdd:pfam01465    1 GANLEYLKNVLLQFLESKESSERKQLLPVIATLLKFSPEEEQKI 44
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
70-751 2.08e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 2.08e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775    70 TDDIIKALTERLDAILLEKAETEQQCLSLKKENIKMKQEVEDSVTKMEDAHKE---LEQSHINYVKEIENLKNELMAVRA 146
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEisrLEQQKQILRERLANLERQLEELEA 323
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   147 KYSEDKA---NLQKELEEAMNKQLELSEQLKFQNNSEDNVKKLQEEIEKIRPAFEEQILYLQKQLDattdEKKETVTQLQ 223
Cdd:TIGR02168  324 QLEELESkldELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA----QLELQIASLN 399
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   224 NIIEANSQHyqknINSLQEELLQLKAIHQEEVKELMcqiEASAKEHETEINKLNELKENLVKQCEASEKNIQEKYECELE 303
Cdd:TIGR02168  400 NEIERLEAR----LERLEDRRERLQQEIEELLKKLE---EAELKELQAELEELEEELEELQEELERLEEALEELREELEE 472
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   304 NLRKATSNANQDNQMCSLLFQENTFVEQV--VNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFH 381
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLegFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVV 552
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   382 EREDLEFKINELLLAKEEQGCVIEKLKSEL-AGLNKQFCCTVEQHNKEVQSLKE--QHQKEISELNETFLSDS------- 451
Cdd:TIGR02168  553 ENLNAAKKAIAFLKQNELGRVTFLPLDSIKgTEIQGNDREILKNIEGFLGVAKDlvKFDPKLRKALSYLLGGVlvvddld 632
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   452 ------------------EKEKLTLMFEIQGLKEQCDNLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQ 513
Cdd:TIGR02168  633 nalelakklrpgyrivtlDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE 712
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   514 QqasdVHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQQElvpELENTIKNLEEKNGVYLLSLSQRDTMLKELEAKIN 593
Cdd:TIGR02168  713 E----LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA---QLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   594 SLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLM 673
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   674 VQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKNDVI-----LKEHITELEKKLQLMVEERDNLNKLL 748
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRreleeLREKLAQLELRLEGLEVRIDNLQERL 945

                   ...
gi 966982775   749 ENE 751
Cdd:TIGR02168  946 SEE 948
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
99-951 7.59e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.39  E-value: 7.59e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775    99 KKENIKMKQEVEDSVTKMEDAHKELE-------------QSHINYVKEIENLKNELMAVRAKYSEDKANLQKELEEAMNK 165
Cdd:TIGR02168  174 RKETERKLERTRENLDRLEDILNELErqlkslerqaekaERYKELKAELRELELALLVLRLEELREELEELQEELKEAEE 253
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   166 QLElseqlkfqnNSEDNVKKLQEEIEKIRPAF---EEQILYLQKQLDATTDEKKETVTQLQnIIEANSQHYQKNINSLQE 242
Cdd:TIGR02168  254 ELE---------ELTAELQELEEKLEELRLEVselEEEIEELQKELYALANEISRLEQQKQ-ILRERLANLERQLEELEA 323
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   243 ELLQLKAiHQEEVKELMCQIEASAKEHETEINKLNELKENLVKQCEASEKNIQEKYEcELENLRKATSNANQDnqmcsll 322
Cdd:TIGR02168  324 QLEELES-KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQ------- 394
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   323 fqentfvEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIK-DEFFHEREDLEFKINELLLAKEEQG 401
Cdd:TIGR02168  395 -------IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELR 467
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   402 CVIEKLKSELAGLNKQFCcTVEQHNKEVQSLKEQHQKEISELNETFLSDSEKEkltlmfEIQGLKEQCDNLQQEKQEAIL 481
Cdd:TIGR02168  468 EELEEAEQALDAAERELA-QLQARLDSLERLQENLEGFSEGVKALLKNQSGLS------GILGVLSELISVDEGYEAAIE 540
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   482 NYeslreIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQQELVPELE 561
Cdd:TIGR02168  541 AA-----LGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   562 NTIKNLeeKNGVYLL-SLSQRDTMLKELEAKINSLTEEkDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQY 640
Cdd:TIGR02168  616 KALSYL--LGGVLVVdDLDNALELAKKLRPGYRIVTLD-GDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEK 692
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   641 NSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKND 720
Cdd:TIGR02168  693 IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   721 -----VILKEHITELEKKLQLMVEERDNLNKLLENEQVQKLFVKTQLYGFLKDMGSEVSEDGEEKDVVNILQAVSESLAK 795
Cdd:TIGR02168  773 aeeelAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   796 INEEKCNLVFQCDKKVFELEKEIKCLQEESVVQCEELKSLLRDYEQekvlLRKELEEIQSEKEALQSDLLEMKNANEKTR 875
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE----LSEELRELESKRSELRRELEELREKLAQLE 928
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   876 LENQNLLIQVEevsqtcNKNEIHNEKEKCSIKEHENLKPLLEQKESELRDtraELILLKDSLAKSPSV------------ 943
Cdd:TIGR02168  929 LRLEGLEVRID------NLQERLSEEYSLTLEEAEALENKIEDDEEEARR---RLKRLENKIKELGPVnlaaieeyeelk 999
                          890
                   ....*....|....*..
gi 966982775   944 ---------QNDLLSSV 951
Cdd:TIGR02168 1000 erydfltaqKEDLTEAK 1016
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1074-1416 2.28e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 2.28e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1074 EDLLARIETlqsNAKLLEVQILEVQRAKAMVDKELEAEK----LQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQE 1149
Cdd:TIGR02168  192 EDILNELER---QLKSLERQAEKAERYKELKAELRELELallvLRLEELREELEELQEELKEAEEELEELTAELQELEEK 268
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1150 LELVKKdaqqttlmnmEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQL 1229
Cdd:TIGR02168  269 LEELRL----------EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1230 LVKTKKELAdskQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKtSAEQHQRTLSAYRQRVTALQE 1309
Cdd:TIGR02168  339 LAELEEKLE---ELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-QIASLNNEIERLEARLERLED 414
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1310 ESRAAKAEQATVTSEFESykvrvHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQMNVSELQTLQS 1389
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEE-----AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489
                          330       340
                   ....*....|....*....|....*....
gi 966982775  1390 EHDTL--LERHNKMLQETVSKEAELREKL 1416
Cdd:TIGR02168  490 RLDSLerLQENLEGFSEGVKALLKNQSGL 518
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
115-712 2.80e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.47  E-value: 2.80e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  115 KMEDAHKELEQSHINYVKEIENLKNELMAvRAKYSEDKANLQKELEEAMNKQLELSEQLKFQNNSEDNVKKLQEEIEKIR 194
Cdd:PRK03918  159 DYENAYKNLGEVIKEIKRRIERLEKFIKR-TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELK 237
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  195 PAFEEqilyLQKQLDATTDEKKEtvtqlqniIEANSQHYQKNINSLQEELLQLKaihqEEVKELmcqieASAKEHETEIN 274
Cdd:PRK03918  238 EEIEE----LEKELESLEGSKRK--------LEEKIRELEERIEELKKEIEELE----EKVKEL-----KELKEKAEEYI 296
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  275 KLNELKENLVKQCEASEKNIqEKYECELENLRKATSNANQDNqmcsllfqentfveqvvnEKVKHLEDTLKELESQHSIL 354
Cdd:PRK03918  297 KLSEFYEEYLDELREIEKRL-SRLEEEINGIEERIKELEEKE------------------ERLEELKKKLKELEKRLEEL 357
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  355 KDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQfcctVEQHNKEVQSLK- 433
Cdd:PRK03918  358 EERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE----IKELKKAIEELKk 433
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  434 -------------EQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCDNLQQE--KQEAILNYESLREIMEILQTELG 498
Cdd:PRK03918  434 akgkcpvcgreltEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVlkKESELIKLKELAEQLKELEEKLK 513
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  499 EsagkisqefesmkqqqaSDVHELQQKLRtaftEKDALLETVNHLQGENEKLLSQQELVPELENTIKNLEEKNGVYLLSL 578
Cdd:PRK03918  514 K-----------------YNLEELEKKAE----EYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEEL 572
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  579 SQRDTMLKELEAKINSLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEEt 658
Cdd:PRK03918  573 AELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE- 651
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....
gi 966982775  659 lKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLE 712
Cdd:PRK03918  652 -LEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
589-1275 3.56e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.08  E-value: 3.56e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   589 EAKINSLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQK 668
Cdd:TIGR02168  224 ELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ 303
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   669 LEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKNDviLKEHITELEKKLQLMVEERDNLNKLL 748
Cdd:TIGR02168  304 KQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELES--LEAELEELEAELEELESRLEELEEQL 381
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   749 EN---EQVQKLFVKTQLYGFLKDMGSEVSEDGEEKDvvNILQAVSESLAKINE-EKCNLVFQCDKKVFELEKEIKCLqEE 824
Cdd:TIGR02168  382 ETlrsKVAQLELQIASLNNEIERLEARLERLEDRRE--RLQQEIEELLKKLEEaELKELQAELEELEEELEELQEEL-ER 458
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   825 SVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANE--KTRLENQNL----------LIQVEEVSQTC 892
Cdd:TIGR02168  459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEgvKALLKNQSGlsgilgvlseLISVDEGYEAA 538
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   893 ---------------NKNEI--------HNEKEKC------SIKEHENLKPLLEQKESELRDTRAELILLKDSLAKSPSV 943
Cdd:TIGR02168  539 ieaalggrlqavvveNLNAAkkaiaflkQNELGRVtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAL 618
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   944 QN--------------------------------DLL--------------SSVKELEEKLENLEKEGKEKEEKINKikl 977
Cdd:TIGR02168  619 SYllggvlvvddldnalelakklrpgyrivtldgDLVrpggvitggsaktnSSILERRREIEELEEKIEELEEKIAE--- 695
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   978 vavkAKKELDSSRKETQTVREELESLRSEKDQLSasmRDLIQAAESYKNLLLEYEKQSEQLDVEKERANNFEHHVEDLTR 1057
Cdd:TIGR02168  696 ----LEKALAELRKELEELEEELEQLRKELEELS---RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1058 QLRNSTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKamvdKELEAEKLQKEQKIKEHATTVNELEELQVQLQ 1137
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL----TLLNEEAANLRERLESLERRIAATERRLEDLE 844
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1138 KEKKQLQKTMQELELVKKDAQ--------QTTLMNMEIADYERLMKELNQKLSNKNNKIEDLEQEIKiqkqkqeTLQEEI 1209
Cdd:TIGR02168  845 EQIEELSEDIESLAAEIEELEelieelesELEALLNERASLEEALALLRSELEELSEELRELESKRS-------ELRREL 917
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966982775  1210 TSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLI-LQASLKGELEASQQQVEVYKIQLAEI 1275
Cdd:TIGR02168  918 EELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEaLENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
984-1239 4.10e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 4.10e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   984 KELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKERAnnfehhvedLTRQLRNST 1063
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLR---------VKEKIGELE 300
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1064 LQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQL 1143
Cdd:TIGR02169  301 AEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF 380
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1144 QKTMQELELVKKDAQQTTL----MNMEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQY 1219
Cdd:TIGR02169  381 AETRDELKDYREKLEKLKReineLKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQL 460
                          250       260
                   ....*....|....*....|
gi 966982775  1220 EEKNTKIKQLLVKTKKELAD 1239
Cdd:TIGR02169  461 AADLSKYEQELYDLKEEYDR 480
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
1619-1663 6.29e-10

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 56.07  E-value: 6.29e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*
gi 966982775   1619 ANLEYLKNVLLQFIFLKPgSERERLLPVINTMLQLSPEEKGKLAA 1663
Cdd:smart00755    2 ANFEYLKNVLLQFLTLRE-SERETLLPVISTVLQLSPEEMQKLLE 45
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
999-1280 2.85e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 2.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   999 ELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKERANNfehHVEDLTRQLRNSTLQCEKINSDNEDLLA 1078
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE---EIEELQKELYALANEISRLEQQKQILRE 309
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1079 RIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAq 1158
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV- 388
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1159 qttlmnmeiadyerlmKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKntKIKQLLVKTKKELA 1238
Cdd:TIGR02168  389 ----------------AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELEEELE 450
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 966982775  1239 DSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKH 1280
Cdd:TIGR02168  451 ELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
92-734 9.72e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 60.52  E-value: 9.72e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775    92 EQQCLSLKKENIKMK---QEVEDSVTKMEDAHKELEQSHINYVKEIENLKNELMAVRAkysedkanLQKELEEAMNKQLE 168
Cdd:pfam15921  102 EKQKFYLRQSVIDLQtklQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKC--------LKEDMLEDSNTQIE 173
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   169 lseQLKFQNNSEDNVkklQEEIEKIRPAFEE---QILYLQKQLDATTDEKKET-VTQLQNIIEANSQHYQKNINSLQEEL 244
Cdd:pfam15921  174 ---QLRKMMLSHEGV---LQEIRSILVDFEEasgKKIYEHDSMSTMHFRSLGSaISKILRELDTEISYLKGRIFPVEDQL 247
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   245 LQLKAIHQEEVKELMCQ----IEASAKEHETEINKLNELKENLVKQCEAseknIQEKYECELENLRKATSNanqdnQMCS 320
Cdd:pfam15921  248 EALKSESQNKIELLLQQhqdrIEQLISEHEVEITGLTEKASSARSQANS----IQSQLEIIQEQARNQNSM-----YMRQ 318
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   321 LLFQENTF--VEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKE 398
Cdd:pfam15921  319 LSDLESTVsqLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKE 398
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   399 E----------QGCVIEKLKSELAGLN---KQFCCTVEQHNKEVQSLKEQHQKEISELNETFLSDSekeklTLMFEIQGL 465
Cdd:pfam15921  399 QnkrlwdrdtgNSITIDHLRRELDDRNmevQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVS-----SLTAQLEST 473
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   466 KEQCDNLQQEKQEAILNYESLREIMEILQTELGESAGKI---SQEFESMKQQQASDVHELQ----------------QKL 526
Cdd:pfam15921  474 KEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIeatNAEITKLRSRVDLKLQELQhlknegdhlrnvqtecEAL 553
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   527 RTAFTEKDALLETVNHLQGENEKLLSQ--------QELVPELENTIKNLEEKNGVYLLSLSQRDTMLKELEAKINSL--- 595
Cdd:pfam15921  554 KLQMAEKDKVIEILRQQIENMTQLVGQhgrtagamQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLele 633
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   596 ------------------TEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQ--------YNSELEQKVN 649
Cdd:pfam15921  634 kvklvnagserlravkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNklkmqlksAQSELEQTRN 713
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   650 ELTG-------------GLEETLKEK----DQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLE 712
Cdd:pfam15921  714 TLKSmegsdghamkvamGMQKQITAKrgqiDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELE 793
                          730       740
                   ....*....|....*....|..
gi 966982775   713 VFLSQKNDviLKEHITELEKKL 734
Cdd:pfam15921  794 VLRSQERR--LKEKVANMEVAL 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
619-1222 1.33e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 1.33e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  619 KCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLmvqmkvlSEDKEVLSAEVKSLYEENN 698
Cdd:COG1196   219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL-------RLELEELELELEEAQAEEY 291
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  699 KLSSEKKQLSRDLEVFLSQKNDviLKEHITELEKKLQLMVEERDNLNKLLENEQVQKLFVKTQLygflkdMGSEVSEDGE 778
Cdd:COG1196   292 ELLAELARLEQDIARLEERRRE--LEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL------EEAEAELAEA 363
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  779 EKDVVNILQAVSESLAKINEEKcNLVFQCDKKVFELEKEIKCLQEesvvQCEELKSLLRDYEQEKVLLRKELEEIQSEKE 858
Cdd:COG1196   364 EEALLEAEAELAEAEEELEELA-EELLEALRAAAELAAQLEELEE----AEEALLERLERLEEELEELEEALAELEEEEE 438
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  859 ALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCNKNEIHNEKEKCSIKEHENLKPLLEQKEsELRDTRAELILLKDSLA 938
Cdd:COG1196   439 EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE-ADYEGFLEGVKAALLLA 517
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  939 KSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIKLVAVKAKKELDSSRKETQTVREELESLRSEKDQLSASMRDLI 1018
Cdd:COG1196   518 GLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAI 597
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1019 QAAESYKNLLLEYEKQSEQL--------DVEKERANNFEHHVEDLTRQLRNSTLQCEKINSDNEDLL-ARIETLQSNAKL 1089
Cdd:COG1196   598 GAAVDLVASDLREADARYYVlgdtllgrTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGgSRRELLAALLEA 677
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1090 LEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIAD 1169
Cdd:COG1196   678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966982775 1170 YERLMKELNQKLSNKNNKIEDLE----------QEIKIQKQ----KQETLQEEITSLQSSVQQYEEK 1222
Cdd:COG1196   758 EPPDLEELERELERLEREIEALGpvnllaieeyEELEERYDflseQREDLEEARETLEEAIEEIDRE 824
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
85-1481 1.75e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 60.07  E-value: 1.75e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775    85 LLEKAETEQQCLSLKKENIKMKQEVEDSVTKMEDAHKELEQSH---INYVKE--IENLKNELMAVRAKYSEDKAN----- 154
Cdd:TIGR01612  326 LIKILESEGEQGHIINKLIFLEKEFEDTIHKSDIYKDECLSNHlfmEDYLKDdkISPYYYEFLEEIKKIAKQRAIffyna 405
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   155 --------LQKELEEAMNKQLELSEQLKFQNNSEDNVKKLQEEIEKI-RPAFEEQILYLQKQLDATTDEkketvtqlqni 225
Cdd:TIGR01612  406 kklkhleiLYKHQEDILNNFHKTIERLIFEKPDPNNNNIFKDDFDEFnKPIPKSKLKALEKRFFEIFEE----------- 474
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   226 iEANSQHYQKNI--NSLQEELLQLKAIHQEEVKELMCQIEASAKEHETEINK-LNELKENLVKQCEAS-EKNIQEKYECe 301
Cdd:TIGR01612  475 -EWGSYDIKKDIdeNSKQDNTVKLILMRMKDFKDIIDFMELYKPDEVPSKNIiGFDIDQNIKAKLYKEiEAGLKESYEL- 552
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   302 LENLRKatsnanqdnqmcsLLFQENTFVEQVvNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFH 381
Cdd:TIGR01612  553 AKNWKK-------------LIHEIKKELEEE-NEDSIHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNISDKNEY 618
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   382 EREDLEFK---------INEllLAKEEQGCVIEKLKSE-------LAGLNKQFCCTVEQHNKEVQSLKEQHQKEISElNE 445
Cdd:TIGR01612  619 IKKAIDLKkiiennnayIDE--LAKISPYQVPEHLKNKdkiystiKSELSKIYEDDIDALYNELSSIVKENAIDNTE-DK 695
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   446 TFLS------DSEKEKLTLMfEIQGLKEQCDNLQQEKQEAIlnyESLREIMEILQTELGESAGKISQEFESMKQQQASDV 519
Cdd:TIGR01612  696 AKLDdlkskiDKEYDKIQNM-ETATVELHLSNIENKKNELL---DIIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKI 771
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   520 HELQQKLRTAFTEKDALLETVNHLQgenekllSQQELVPELENTIKNLEEKNGVYLLSLSQRDtmlKELEAKINSLTEEK 599
Cdd:TIGR01612  772 NDYAKEKDELNKYKSKISEIKNHYN-------DQINIDNIKDEDAKQNYDKSKEYIKTISIKE---DEIFKIINEMKFMK 841
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   600 DDFINKLkNSYEEMDNFHK-KCEREERLILELGKKV--EQTTQYNSELEQKVNELTGGLEET---LKEKDQNDQKLEKLM 673
Cdd:TIGR01612  842 DDFLNKV-DKFINFENNCKeKIDSEHEQFAELTNKIkaEISDDKLNDYEKKFNDSKSLINEInksIEEEYQNINTLKKVD 920
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   674 VQMKVLSEDKEvlsaEVKSLYEENNKLSSEKKQ------LSRDLEVFLSQKNDVILKEHITELEK---KLQLMVEERDN- 743
Cdd:TIGR01612  921 EYIKICENTKE----SIEKFHNKQNILKEILNKnidtikESNLIEKSYKDKFDNTLIDKINELDKafkDASLNDYEAKNn 996
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   744 -----LNKLLENEQVQKLFVKTQLYGFLKDMGSEVSEDGEE--KDVVNILQAVSESLAKINEEKCNLVfqcDKKVFELEK 816
Cdd:TIGR01612  997 elikyFNDLKANLGKNKENMLYHQFDEKEKATNDIEQKIEDanKNIPNIEIAIHTSIYNIIDEIEKEI---GKNIELLNK 1073
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   817 EIKCLQEESVVQCEELKSLLRDY------EQEKVLLRKELEEIQSEKEALQ-------SDLLEMKNANEKTRLENQNLLI 883
Cdd:TIGR01612 1074 EILEEAEINITNFNEIKEKLKHYnfddfgKEENIKYADEINKIKDDIKNLDqkidhhiKALEEIKKKSENYIDEIKAQIN 1153
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   884 QVEEVSQTCnkneIHNEKEKCSIKEHENLKPLLEQKE------SELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEK 957
Cdd:TIGR01612 1154 DLEDVADKA----ISNDDPEEIEKKIENIVTKIDKKKniydeiKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLE 1229
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   958 LENLEKEGKEKEEKINKIKLvavkakKELDSSRKETQtvreELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQ 1037
Cdd:TIGR01612 1230 KIDEEKKKSEHMIKAMEAYI------EDLDEIKEKSP----EIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDEN 1299
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1038 LDVEKERA------NNFEHHVEDLTRQLRNSTLQCEKINSDNEDLLARIETLQSnakllevqILEVQRAKAMVDKELEAE 1111
Cdd:TIGR01612 1300 ISDIREKSlkiiedFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYN--------ILKLNKIKKIIDEVKEYT 1371
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1112 KlqkeqKIKEHATTVNEleelqvQLQKEKKQLQKTMQELELVK-KDAQQTTLMNMEIadyerlmKELNQKLSNKNNKIED 1190
Cdd:TIGR01612 1372 K-----EIEENNKNIKD------ELDKSEKLIKKIKDDINLEEcKSKIESTLDDKDI-------DECIKKIKELKNHILS 1433
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1191 LEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNtkikQLLVKTKKEladskQAETDHLILQASLKGELEASQQqvevYKI 1270
Cdd:TIGR01612 1434 EESNIDTYFKNADENNENVLLLFKNIEMADNKS----QHILKIKKD-----NATNDHDFNINELKEHIDKSKG----CKD 1500
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1271 QlaeitSEKHkihehlKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTSEFESYKVRvhNVLKQQKNKSMSQAETE 1350
Cdd:TIGR01612 1501 E-----ADKN------AKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIII--KEIKDAHKKFILEAEKS 1567
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1351 GAKQEREHLEMLIDQLKIKLQDSQN----NLQMNVSELQTLQSEHDTLLERHNKMLQETVSKEAELREklCSIQSENMMM 1426
Cdd:TIGR01612 1568 EQKIKEIKKEKFRIEDDAAKNDKSNkaaiDIQLSLENFENKFLKISDIKKKINDCLKETESIEKKISS--FSIDSQDTEL 1645
                         1450      1460      1470      1480      1490
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 966982775  1427 KsehtQTVSQLTSQNEVLRnSFRDQVRHLqEEHRKTVETLQQQLSRVEAQLFQLK 1481
Cdd:TIGR01612 1646 K----ENGDNLNSLQEFLE-SLKDQKKNI-EDKKKELDELDSEIEKIEIDVDQHK 1694
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
622-1317 2.39e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 2.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   622 REERLILElgkKVEQTTQYNSELEQKVNELtgglEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLsaevkslyEENNKLS 701
Cdd:TIGR02169  153 VERRKIID---EIAGVAEFDRKKEKALEEL----EEVEENIERLDLIIDEKRQQLERLRREREKA--------ERYQALL 217
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   702 SEKkqlsRDLEVFLSQKNDVILKEHITELEKKLQLMVEERDNLNKLLEnEQVQKLFVKTQLygfLKDMGSEVSEDGEEKD 781
Cdd:TIGR02169  218 KEK----REYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEIS-ELEKRLEEIEQL---LEELNKKIKDLGEEEQ 289
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   782 VvnilqAVSESLAKINEEkcnlVFQCDKKVFELEKEIKCLQEESVVQCEELKSLLRDYEQekvlLRKELEEIQSEKEALQ 861
Cdd:TIGR02169  290 L-----RVKEKIGELEAE----IASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEE----LEREIEEERKRRDKLT 356
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   862 SDLLEMKNANEKTRLENQNL----LIQVEEVSQTCNKNEIHNEKEKCSIKEHENLKPLLEQKESELRDTRAELILLKDSL 937
Cdd:TIGR02169  357 EEYAELKEELEDLRAELEEVdkefAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKI 436
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   938 AKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEK--INKIKLVAV-----KAKKELDSSRKETQTVREELESLRSEKDQL 1010
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQElyDLKEEYDRVekelsKLQRELAEAEAQARASEERVRGGRAVEEVL 516
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1011 SAS-------MRDLIQAAESYKNLL----------------------LEYEK---------------QSEQLDVEKERAN 1046
Cdd:TIGR02169  517 KASiqgvhgtVAQLGSVGERYATAIevaagnrlnnvvveddavakeaIELLKrrkagratflplnkmRDERRDLSILSED 596
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1047 ----------NFEHHVEDLTRQLRNSTLQCEKINSDNEDLL-ARIETL---------------------QSNAKLLEVQI 1094
Cdd:TIGR02169  597 gvigfavdlvEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGkYRMVTLegelfeksgamtggsraprggILFSRSEPAEL 676
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1095 LEVQRAKAMVDKELEAekLQKEQKIKEhattvNELEELQVQLQKEKKQLQKTMQELELVKKDAQQttlMNMEIADYERLM 1174
Cdd:TIGR02169  677 QRLRERLEGLKRELSS--LQSELRRIE-----NRLDELSQELSDASRKIGEIEKEIEQLEQEEEK---LKERLEELEEDL 746
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1175 KELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSL-----QSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLI 1249
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL 826
                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 966982775  1250 LQASLKGELEASQQQVEVYKIQLAEITSEKHKIH---EHLKTSAEQHQRTLSAYRQRVTALQEESRAAKAE 1317
Cdd:TIGR02169  827 EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNgkkEELEEELEELEAALRDLESRLGDLKKERDELEAQ 897
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
981-1221 3.00e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 3.00e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   981 KAKKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKqseqlDVEKERANNFEHHVEDLTRQLR 1060
Cdd:TIGR02169  734 KLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA-----RLSHSRIPEIQAELSKLEEEVS 808
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1061 NSTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKE---QKIKEHATTVNELEELQVQLQ 1137
Cdd:TIGR02169  809 RIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEeleEELEELEAALRDLESRLGDLK 888
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1138 KEKKQLQKTMQELELVKKDAqqttlmNMEIADYERLMKELNQKLSNKNNKIEDLEQEI--------------KIQKQKQE 1203
Cdd:TIGR02169  889 KERDELEAQLRELERKIEEL------EAQIEKKRKRLSELKAKLEALEEELSEIEDPKgedeeipeeelsleDVQAELQR 962
                          250       260
                   ....*....|....*....|..
gi 966982775  1204 tLQEEITSLQS----SVQQYEE 1221
Cdd:TIGR02169  963 -VEEEIRALEPvnmlAIQEYEE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
822-1366 4.13e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 4.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  822 QEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEvsqtcnKNEIHNEK 901
Cdd:COG1196   220 EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE------AQAEEYEL 293
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  902 EKCSIKEHENLKPLLEQKEsELRDTRAELILLKDSLAKSpsvQNDLLSSVKELEEKLENLEKEGKEkeekinkiklvavk 981
Cdd:COG1196   294 LAELARLEQDIARLEERRR-ELEERLEELEEELAELEEE---LEELEEELEELEEELEEAEEELEE-------------- 355
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  982 AKKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKERAnnfEHHVEDLTRQLRN 1061
Cdd:COG1196   356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL---EEELEELEEALAE 432
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1062 STLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKK 1141
Cdd:COG1196   433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1142 QLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEE 1221
Cdd:COG1196   513 ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAL 592
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1222 KNTKIKQ---LLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLS 1298
Cdd:COG1196   593 ARGAIGAavdLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLA 672
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966982775 1299 AYRQRVTALQEESRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQL 1366
Cdd:COG1196   673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
1101-1472 2.71e-07

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 55.83  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1101 KAMVDKELEAEKLQKEQKIKEHATTVNELEELQVqlqkekkqLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQK 1180
Cdd:PRK10929   16 GAYAATAPDEKQITQELEQAKAAKTPAQAEIVEA--------LQSALNWLEERKGSLERAKQYQQVIDNFPKLSAELRQQ 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1181 LSNKNNKIEDLEQEIKIQKQKQETLQeeITSlqssvqqyeekntkikQLLvktkkELADSKQAETDHLILQASLKGELea 1260
Cdd:PRK10929   88 LNNERDEPRSVPPNMSTDALEQEILQ--VSS----------------QLL-----EKSRQAQQEQDRAREISDSLSQL-- 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1261 SQQQVEVYKiQLAEITSeKHKIHEHLKTSAEQHQRtlsayrqrvTALQEESRAAKAeqatVTSEFESYKVRVHNvlKQQk 1340
Cdd:PRK10929  143 PQQQTEARR-QLNEIER-RLQTLGTPNTPLAQAQL---------TALQAESAALKA----LVDELELAQLSANN--RQE- 204
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1341 nksMSQAETEGAKQEREHLEMLIDQLKIKLqdsqNNLQMNVSElQTLqsEHDTLLERHNKMLQETVSKEAELREKLCSI- 1419
Cdd:PRK10929  205 ---LARLRSELAKKRSQQLDAYLQALRNQL----NSQRQREAE-RAL--ESTELLAEQSGDLPKSIVAQFKINRELSQAl 274
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 966982775 1420 --QSENM-MMKSEHTQTVSQLTSQNEVLrNSFRDQVRHLQEEhrkTV--ETLQQQLSR 1472
Cdd:PRK10929  275 nqQAQRMdLIASQQRQAASQTLQVRQAL-NTLREQSQWLGVS---NAlgEALRAQVAR 328
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
977-1232 3.01e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 3.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   977 LVAVKAKKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKERANnfeHHVEDLT 1056
Cdd:TIGR02169  667 LFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLK---ERLEELE 743
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1057 RQLRNSTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVD-KELEAEKLQKEQKIKEHATTVNELEELQVQ 1135
Cdd:TIGR02169  744 EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNR 823
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1136 LQKEKKQLQKTMQELELVKKDAQ-QTTLMNMEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQS 1214
Cdd:TIGR02169  824 LTLEKEYLEKEIQELQEQRIDLKeQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903
                          250       260
                   ....*....|....*....|..
gi 966982775  1215 SVQQ----YEEKNTKIKQLLVK 1232
Cdd:TIGR02169  904 KIEEleaqIEKKRKRLSELKAK 925
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
814-1458 2.65e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.66  E-value: 2.65e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   814 LEKEIKCLQEESVVQCEELKSL--LRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTR--------LENQNLLI 883
Cdd:TIGR00618  224 LEKELKHLREALQQTQQSHAYLtqKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINrarkaaplAAHIKAVT 303
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   884 QVEEVSQTCNKNEIHNEKEKCSIKEHENLKPLLEQKESELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEK 963
Cdd:TIGR00618  304 QIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHT 383
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   964 EGKEKEEKINKIKLvavkAKKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKE 1043
Cdd:TIGR00618  384 LQQQKTTLTQKLQS----LCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKI 459
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1044 RANNFEHHVEDLTRQLRNSTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDkELEAEKLQKEQKIKEHA 1123
Cdd:TIGR00618  460 HLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDID-NPGPLTRRMQRGEQTYA 538
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1124 TTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMN---MEIADYERLMKELNQKLSNKNNKIED----LEQEIK 1196
Cdd:TIGR00618  539 QLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDnrsKEDIPNLQNITVRLQDLTEKLSEAEDmlacEQHALL 618
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1197 IQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKE-----LADSKQAETDHLILQASLKGELEASQQQVEVYKIQ 1271
Cdd:TIGR00618  619 RKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQErvrehALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEM 698
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1272 LAEITSEKHKIHEHLKTSAEQhqrtlsayrqrvtaLQEESRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEG 1351
Cdd:TIGR00618  699 LAQCQTLLRELETHIEEYDRE--------------FNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHF 764
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1352 AKQEREHLEMLID----QLKIKLQDSQNNLQMNVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMMK 1427
Cdd:TIGR00618  765 NNNEEVTAALQTGaelsHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATL 844
                          650       660       670
                   ....*....|....*....|....*....|.
gi 966982775  1428 SEHTQTVSQLTSQNEVLRNSFRDQVRHLQEE 1458
Cdd:TIGR00618  845 GEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
627-1416 2.73e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.67  E-value: 2.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   627 ILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKL--SSEK 704
Cdd:pfam02463  137 FLVQGGKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALeyYQLK 216
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   705 KQLSRDLEVFLSQKNDVILKEHITELEKKLQLMVEERDNLNKLLENEQVQKLFVKTQLYGFLKDMGSEVSEDGEEKDVVN 784
Cdd:pfam02463  217 EKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEE 296
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   785 ILQAVSESLAKINEEKCNLVFQCDKKVFELEKEIKCLQEESVVQCEELKSLLRDYEQEKV----LLRKELEEIQSEKEAL 860
Cdd:pfam02463  297 ELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEeeeeLEKLQEKLEQLEEELL 376
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   861 QSDLLEMKNANEKTRLENQNLLIQVEEVSQTCNKNEIHNEKEKCSIKEHENLKPLLEQKESELRDTRAELILLKDSLAKS 940
Cdd:pfam02463  377 AKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQ 456
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   941 PSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIKLVAVKAKKELDSSRKETQTVREELESLRSEK-DQLSASMRDLIQ 1019
Cdd:pfam02463  457 ELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRiISAHGRLGDLGV 536
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1020 AAESYKNL-LLEYEKQSEQLDVEKERANNFEHHVEDLTRQLRNSTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQ 1098
Cdd:pfam02463  537 AVENYKVAiSTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEAD 616
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1099 RAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELN 1178
Cdd:pfam02463  617 EDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1179 QKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGEL 1258
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1259 EASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTSEFESYKVRVHNVLKQ 1338
Cdd:pfam02463  777 AEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEEL 856
                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966982775  1339 QKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQMNVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKL 1416
Cdd:pfam02463  857 ERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE 934
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
922-1416 2.79e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 2.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  922 ELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIKLVAVKAKKELDSSRKETQTVREELE 1001
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1002 SLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKERAnnfEHHVEDLTRQLRNSTLQCEKINSDNEDLLARIE 1081
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA---EAELAEAEEALLEAEAELAEAEEELEELAEELL 389
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1082 TLQSNAKLLEVQILEVQRAKAmvdkELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELvkkdaqqtt 1161
Cdd:COG1196   390 EALRAAAELAAQLEELEEAEE----ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE--------- 456
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1162 lmnmEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTK------K 1235
Cdd:COG1196   457 ----EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvavligV 532
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1236 ELADSKQAETDHLILQASLKGELEASQQQVEVY---------------KIQLAEITSEKHKIHEHLK----TSAEQHQRT 1296
Cdd:COG1196   533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYlkaakagratflpldKIRARAALAAALARGAIGAavdlVASDLREAD 612
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1297 LSAYRQRVTALQEESRAAKAEQATVTSEFESYKVRVhnVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNN 1376
Cdd:COG1196   613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE--VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|
gi 966982775 1377 LQMNVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKL 1416
Cdd:COG1196   691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1067-1332 3.74e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.94  E-value: 3.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1067 EKINSDNEDLLARIETLQSNAKLLEV---QILEV-------QRAKAMVDKELEAekLQKEQKIKEHATTVNELEELQVQL 1136
Cdd:COG3206   107 EDPLGEEASREAAIERLRKNLTVEPVkgsNVIEIsytspdpELAAAVANALAEA--YLEQNLELRREEARKALEFLEEQL 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1137 QKEKKQLQKTMQELELVKKD------AQQTTLMNMEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEiT 1210
Cdd:COG3206   185 PELRKELEEAEAALEEFRQKnglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQS-P 263
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1211 SLQSSVQQYEEKNTKIKQLL----------VKTKKELADSKQAetdhliLQASLKGELEASQQQVEVYKIQLAEITSEKH 1280
Cdd:COG3206   264 VIQQLRAQLAELEAELAELSarytpnhpdvIALRAQIAALRAQ------LQQEAQRILASLEAELEALQAREASLQAQLA 337
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 966982775 1281 KIHEHLKTSAEQhQRTLSAYRQRVTALQE--ESRAAKAEQATVTSEFESYKVRV 1332
Cdd:COG3206   338 QLEARLAELPEL-EAELRRLEREVEVARElyESLLQRLEEARLAEALTVGNVRV 390
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
894-1444 4.75e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.56  E-value: 4.75e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   894 KNEIHNEKEKCSIKEHE--NLKPLLEQKESELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEK 971
Cdd:TIGR04523  109 NSEIKNDKEQKNKLEVElnKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKN 188
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   972 INKIKLVAVKAKKELDSSRKETQTVRE---ELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKERANNf 1048
Cdd:TIGR04523  189 IDKIKNKLLKLELLLSNLKKKIQKNKSlesQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK- 267
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1049 ehhvedltrQLRNSTLQCEKINSDNEDLLARIETLQSNAKLLEVQilevqrAKAMVDKELEAEKLQKEQKIKEHATTVNE 1128
Cdd:TIGR04523  268 ---------QLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQ------KEQDWNKELKSELKNQEKKLEEIQNQISQ 332
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1129 LEELQVQLQKEKKQLQKTMQELELVKKDAQ-QTTLMNMEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQE 1207
Cdd:TIGR04523  333 NNKIISQLNEQISQLKKELTNSESENSEKQrELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDE 412
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1208 EITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEItsekhkihehlK 1287
Cdd:TIGR04523  413 QIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKI-----------K 481
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1288 TSAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTSEFESYKVRVhnvlkQQKNKSMSQAETEGAKQEREHLEMLIDQLK 1367
Cdd:TIGR04523  482 QNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKI-----EKLESEKKEKESKISDLEDELNKDDFELKK 556
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966982775  1368 IKLQDSQNNLQMNVSELQtlqsEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVL 1444
Cdd:TIGR04523  557 ENLEKEIDEKNKEIEELK----QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKL 629
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1178-1411 7.97e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 7.97e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1178 NQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAetdhlilQASLKGE 1257
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE-------LAELEKE 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1258 LEASQQQVEVYKIQLAE--ITSEKHKIHEHLK-----TSAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTsefesykv 1330
Cdd:COG4942    92 IAELRAELEAQKEELAEllRALYRLGRQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA-------- 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1331 RVHNVLKQQKNKsmSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQMNVSELQTLQSEHDTLLERHNKMLQETVSKEA 1410
Cdd:COG4942   164 ALRAELEAERAE--LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241

                  .
gi 966982775 1411 E 1411
Cdd:COG4942   242 R 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1070-1292 8.32e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 8.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1070 NSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQE 1149
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1150 LELVKKDAQQTTLMNMEIADYERLMKELNQKLSNKNNKIEDLEQEI-KIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQ 1228
Cdd:COG4942    99 LEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966982775 1229 LLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQ 1292
Cdd:COG4942   179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK11281 PRK11281
mechanosensitive channel MscK;
851-1265 1.03e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 50.68  E-value: 1.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  851 EEIQSEKEALQSD-LLEMKNANEKTRLEN-QNLLIQVEEVSQtcnkneihnekekcsikEHENLKPLLEQKESELRDTRA 928
Cdd:PRK11281   39 ADVQAQLDALNKQkLLEAEDKLVQQDLEQtLALLDKIDRQKE-----------------ETEQLKQQLAQAPAKLRQAQA 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  929 ELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIKLVAV------KAKKELDSSRKETQTVREELES 1002
Cdd:PRK11281  102 ELEALKDDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSlqtqpeRAQAALYANSQRLQQIRNLLKG 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1003 LRSEKDQLSASMRDLIQAAESYKNLLLEYEKQS------------EQLDVEKERANNFEHHVEDL-----TRQLRNSTLQ 1065
Cdd:PRK11281  182 GKVGGKALRPSQRVLLQAEQALLNAQNDLQRKSlegntqlqdllqKQRDYLTARIQRLEHQLQLLqeainSKRLTLSEKT 261
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1066 CEKinSDNEDLLARIET-------LQSNAKLLEVQILEVQRAKAMVDKELEAEK-----LQKEQKIKEhattvnELEELQ 1133
Cdd:PRK11281  262 VQE--AQSQDEAARIQAnplvaqeLEINLQLSQRLLKATEKLNTLTQQNLRVKNwldrlTQSERNIKE------QISVLK 333
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1134 VQLQKEKKqLQKTMQELelvkKDAQQTTLMNMEIADYeRLMK-ELNQ---KLSNKNNKIEDLEqeikiQKQKQETLQEEI 1209
Cdd:PRK11281  334 GSLLLSRI-LYQQQQAL----PSADLIEGLADRIADL-RLEQfEINQqrdALFQPDAYIDKLE-----AGHKSEVTDEVR 402
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 966982775 1210 TSLQSsvqqyeekntkikqlLVKTKKELAD--SKQaetdhLILQASLKGELEASQQQV 1265
Cdd:PRK11281  403 DALLQ---------------LLDERRELLDqlNKQ-----LNNQLNLAINLQLNQQQL 440
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
603-1176 1.20e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 1.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  603 INKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKdqndQKLEKLMVQMKVLSED 682
Cdd:PRK03918  171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV----KELEELKEEIEELEKE 246
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  683 KEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKNDVilkEHITELEKKLQLMVEERDNLNKLLENEQVQKLFVKTQL 762
Cdd:PRK03918  247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL---KELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEI 323
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  763 YGFLKDMgsevsEDGEEKdvvnilqavSESLAKINEEKCNLvfqcDKKVFELEKEIKCLQE--ESVVQCEELKSLLRDYE 840
Cdd:PRK03918  324 NGIEERI-----KELEEK---------EERLEELKKKLKEL----EKRLEELEERHELYEEakAKKEELERLKKRLTGLT 385
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  841 QEKvlLRKELEEIQSEKEALQ---SDLLEMKNANEKTRLENQNLLIQVEEVSQTCN--KNEIHNEKEKCSIKEH----EN 911
Cdd:PRK03918  386 PEK--LEKELEELEKAKEEIEeeiSKITARIGELKKEIKELKKAIEELKKAKGKCPvcGRELTEEHRKELLEEYtaelKR 463
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  912 LKPLLEQKESELRDTRAELILLKDSLAKSPsvqnDLLSSVKELEEKLENLEKEGKEKEEKINKIKLVAVKAKKELDSSRK 991
Cdd:PRK03918  464 IEKELKEIEEKERKLRKELRELEKVLKKES----ELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKG 539
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  992 ETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQ--SEQLDVEKE------------RANNFEHHVEDLTR 1057
Cdd:PRK03918  540 EIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgfESVEELEERlkelepfyneylELKDAEKELEREEK 619
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1058 QLRNSTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDK-ELEAEKLQKEQKIKEHATTVNELEELQVQL 1136
Cdd:PRK03918  620 ELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYlELSRELAGLRAELEELEKRREEIKKTLEKL 699
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 966982775 1137 QKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKE 1176
Cdd:PRK03918  700 KEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKE 739
46 PHA02562
endonuclease subunit; Provisional
575-813 1.35e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 50.01  E-value: 1.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  575 LLSLSQRDTMLKELEAKINSLTEEKDDFINKLknsyeemDNFHKKCEREERLILELGKKveqTTQYNSELEQKVNELtgg 654
Cdd:PHA02562  159 LLDISVLSEMDKLNKDKIRELNQQIQTLDMKI-------DHIQQQIKTYNKNIEEQRKK---NGENIARKQNKYDEL--- 225
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  655 leetLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVF------------LSQKNDVI 722
Cdd:PHA02562  226 ----VEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYekggvcptctqqISEGPDRI 301
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  723 --LKEHITELEKKLQLMVEERDNLNKLLE--NEQVQKLF-VKTQLYGFLKDMGSEVSEDGEEKDVVNILQA----VSESL 793
Cdd:PHA02562  302 tkIKDKLKELQHSLEKLDTAIDELEEIMDefNEQSKKLLeLKNKISTNKQSLITLVDKAKKVKAAIEELQAefvdNAEEL 381
                         250       260
                  ....*....|....*....|
gi 966982775  794 AKINEEKCNLVFQCDKKVFE 813
Cdd:PHA02562  382 AKLQDELDKIVKTKSELVKE 401
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
74-357 1.43e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.94  E-value: 1.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   74 IKALTERLDAILLEKAETEQQCLSLKKEnikmKQEVEDSVTKMEDAHKELEQSHINYVKEIENLKNELmavrAKYSEDKA 153
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAE----LAELEAELEELRLELEELELELEEAQAEEYELLAEL----ARLEQDIA 305
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  154 NLQKELEEAMNKQLELSEQLKFQNNSEDNVKKLQEEIEKIRPAFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHY 233
Cdd:COG1196   306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  234 QKNINSLQEELLQLKAIHQEEVKELmcQIEASAKEHETEINKLNELKENLVKQCEASEKNIQEKYECELENLRKATSNAN 313
Cdd:COG1196   386 EELLEALRAAAELAAQLEELEEAEE--ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 966982775  314 QDnqmcsllfQENTFVEQVVNEKVKHLEDTLKELESQHSILKDE 357
Cdd:COG1196   464 LL--------AELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1141-1370 1.50e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1141 KQLQKTMQELELVKKdaqqttlmnmEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYE 1220
Cdd:COG4942    20 DAAAEAEAELEQLQQ----------EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1221 EKNTKIKQLLVKTKKELAD------------------SKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKhki 1282
Cdd:COG4942    90 KEIAELRAELEAQKEELAEllralyrlgrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR--- 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1283 hEHLKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTSEFESYKVRVHNVLKQQKN--KSMSQAETEGAKQEREHLE 1360
Cdd:COG4942   167 -AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEleALIARLEAEAAAAAERTPA 245
                         250
                  ....*....|
gi 966982775 1361 MLIDQLKIKL 1370
Cdd:COG4942   246 AGFAALKGKL 255
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1008-1239 1.69e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 1.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1008 DQLSASMRDLiqaaESYKNLLLEYEKQSEQLDVEKERANNFEHHVEDLT--RQLRnSTLQCEKINSDNEDLLARIETLQS 1085
Cdd:COG4913   228 DALVEHFDDL----ERAHEALEDAREQIELLEPIRELAERYAAARERLAelEYLR-AALRLWFAQRRLELLEAELEELRA 302
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1086 NAKLLEVQILEVQRAKamvdKELEAEKLQKEQKIKEHATtvNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTL-MN 1164
Cdd:COG4913   303 ELARLEAELERLEARL----DALREELDELEAQIRGNGG--DRLEQLEREIERLERELEERERRRARLEALLAALGLpLP 376
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966982775 1165 MEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELAD 1239
Cdd:COG4913   377 ASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAE 451
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
334-775 1.73e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.63  E-value: 1.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   334 NEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKdEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAG 413
Cdd:TIGR04523  165 KKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLK-KKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINE 243
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   414 LNKQFCCTVEQHNK---EVQSLKEQHQKEISELNETFLSDSEKEKltlmfEIQGLKEQCDNLQQEKQEAILNY-----ES 485
Cdd:TIGR04523  244 KTTEISNTQTQLNQlkdEQNKIKKQLSEKQKELEQNNKKIKELEK-----QLNQLKSEISDLNNQKEQDWNKElkselKN 318
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   486 LREIMEILQTELGESAGKISQefesMKQQQASDVHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQQELVPELENTIK 565
Cdd:TIGR04523  319 QEKKLEEIQNQISQNNKIISQ----LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQIN 394
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   566 NLEEKNGVYLLSLSQRDTMLKELEAKINSLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELE 645
Cdd:TIGR04523  395 DLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLS 474
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   646 QKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSR---DLEVFLSQKNDVI 722
Cdd:TIGR04523  475 RSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESkisDLEDELNKDDFEL 554
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 966982775   723 LKEHITELEKKLQLMVEERDNLNKLLENEQVQKLFVKTQLYGFLKDMGSEVSE 775
Cdd:TIGR04523  555 KKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEE 607
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
657-894 1.83e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 49.54  E-value: 1.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  657 ETLKEKDQNDQ---KLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQkndvILKEhITELEKK 733
Cdd:PRK05771   34 EDLKEELSNERlrkLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEK----IEKE-IKELEEE 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  734 LQLMVEERDNLNKLLE--------NEQVQKLFVKTQLYGFLkdmgSEVSEDGEEKDVVNILQAVSEsLAKINEEKCNLVF 805
Cdd:PRK05771  109 ISELENEIKELEQEIErlepwgnfDLDLSLLLGFKYVSVFV----GTVPEDKLEELKLESDVENVE-YISTDKGYVYVVV 183
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  806 QCDKKVF-ELEKEIKCL--QEESVVQCEELKSLLRDYEQEkvllrkeLEEIQSEKEALQSDLLEMKNANEKTRLENQNLL 882
Cdd:PRK05771  184 VVLKELSdEVEEELKKLgfERLELEEEGTPSELIREIKEE-------LEEIEKERESLLEELKELAKKYLEELLALYEYL 256
                         250
                  ....*....|..
gi 966982775  883 IQVEEVSQTCNK 894
Cdd:PRK05771  257 EIELERAEALSK 268
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
916-1161 2.28e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  916 LEQKESELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKekeekinkiklvavKAKKELDSSRKETQT 995
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR--------------ALEQELAALEAELAE 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  996 VREELESLRSEKDQLSASMRDLIQAAesYKNLLLEYEKqseqLDVEKERANNFEHHVEDLTRQLRNSTLQCEKINSDNED 1075
Cdd:COG4942    88 LEKEIAELRAELEAQKEELAELLRAL--YRLGRQPPLA----LLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1076 LLARIETLQSNAKLLEVQILEVQRAKamvdKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKK 1155
Cdd:COG4942   162 LAALRAELEAERAELEALLAELEEER----AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237

                  ....*.
gi 966982775 1156 DAQQTT 1161
Cdd:COG4942   238 AAAERT 243
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
985-1218 2.41e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  985 ELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKERANNFEHHVEDLTRQLrnstl 1064
Cdd:COG4913   655 EYSWDEIDVASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEEL----- 729
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1065 qcekinsdnEDLLARIETLQSNAKLLEVQILEVQRAKAMVDkeleaeklQKEQKIKEHATtvNELEELQVQLQKEKKQLQ 1144
Cdd:COG4913   730 ---------DELQDRLEAAEDLARLELRALLEERFAAALGD--------AVERELRENLE--ERIDALRARLNRAEEELE 790
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966982775 1145 KTMQE-LELVKKDAQQTTLMNMEIADYERLMKELnqklsnKNNKIEDLEQEIKIQKQKQETlqEEITSLQSSVQQ 1218
Cdd:COG4913   791 RAMRAfNREWPAETADLDADLESLPEYLALLDRL------EEDGLPEYEERFKELLNENSI--EFVADLLSKLRR 857
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
499-1423 2.49e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.27  E-value: 2.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   499 ESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQQELVPELENTIKNLEEKngvyLLSL 578
Cdd:TIGR00606  189 ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHN----LSKI 264
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   579 SQRDTMLKELEAKINSLTEEKDDFINKLKNSYE-------EMDNFHKKCERE-ERLILELGKKVEQTTQYNSELEQKVNE 650
Cdd:TIGR00606  265 MKLDNEIKALKSRKKQMEKDNSELELKMEKVFQgtdeqlnDLYHNHQRTVREkERELVDCQRELEKLNKERRLLNQEKTE 344
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   651 LtggleetlkEKDQNDQKLEKLMVQMKVLSEDKEVLSaevkslyeenNKLSSEKKQLSRDLEVFLSQKNDVILKEHITEL 730
Cdd:TIGR00606  345 L---------LVEQGRLQLQADRHQEHIRARDSLIQS----------LATRLELDGFERGPFSERQIKNFHTLVIERQED 405
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   731 EKKL--QLMVEERDNLNklLENEQVQKLFVKTQLYGFLKDMGSEVSEDGEE--KDVVNILQAVSESLAKINEEkcnlvfq 806
Cdd:TIGR00606  406 EAKTaaQLCADLQSKER--LKQEQADEIRDEKKGLGRTIELKKEILEKKQEelKFVIKELQQLEGSSDRILEL------- 476
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   807 cDKKVFELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKealqsdllemKNANEKTRLENQNLLIQVE 886
Cdd:TIGR00606  477 -DQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQ----------LNHHTTTRTQMEMLTKDKM 545
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   887 EVSQTCNKNEIHNEKEKCSIKEHENLKPLLE----QKESELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLE 962
Cdd:TIGR00606  546 DKDEQIRKIKSRHSDELTSLLGYFPNKKQLEdwlhSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYE 625
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   963 KEGKEKEEKINKIKlvavkakkELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLdveK 1042
Cdd:TIGR00606  626 DKLFDVCGSQDEES--------DLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAEL---Q 694
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1043 ERANNFEHHVEDLTRQLRNSTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEH 1122
Cdd:TIGR00606  695 EFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL 774
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1123 ATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTlmNMEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQ 1202
Cdd:TIGR00606  775 GTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAA--KLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLI 852
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1203 ETLQEEITSLQSSV---------------------QQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEAS 1261
Cdd:TIGR00606  853 QDQQEQIQHLKSKTnelkseklqigtnlqrrqqfeEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSK 932
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1262 QQQVEVYKIQLAEITSEKHKIHEHLKT-----------SAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTSEFESYKV 1330
Cdd:TIGR00606  933 ETSNKKAQDKVNDIKEKVKNIHGYMKDienkiqdgkddYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKI 1012
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1331 RvHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQMNvsELQTLQSEHDTLLERHNKMLQETVSKEA 1410
Cdd:TIGR00606 1013 Q-ERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEE--NIDLIKRNHVLALGRQKGYEKEIKHFKK 1089
                          970
                   ....*....|...
gi 966982775  1411 ELREKLCSIQSEN 1423
Cdd:TIGR00606 1090 ELREPQFRDAEEK 1102
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
404-760 2.78e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.30  E-value: 2.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   404 IEKLKSELAGLnKQFCCTVEQHNKEVQSLKEQHQKEISEL-NETFLSDSEKEKLT-----LMFEIQGLKEQCDNLQQEKQ 477
Cdd:TIGR02169  683 LEGLKRELSSL-QSELRRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKerleeLEEDLSSLEQEIENVKSELK 761
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   478 EAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVN-HLQGENEKLLSQQEL 556
Cdd:TIGR02169  762 ELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTlEKEYLEKEIQELQEQ 841
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   557 VPELENTIKNLEEKNGVYLLSLSQRDTMLKELEAKINSLTEEkddfinkLKNSYEEMDNFHKKCEREERLILELGKKVEQ 636
Cdd:TIGR02169  842 RIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR-------LGDLKKERDELEAQLRELERKIEELEAQIEK 914
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   637 TTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLsAEVKSLYEENNKLSSEKKQLSRDLEvfls 716
Cdd:TIGR02169  915 KRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVE-EEIRALEPVNMLAIQEYEEVLKRLD---- 989
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 966982775   717 qkndvilkehitELEKKLQLMVEERDNLNKLLE--NEQVQKLFVKT 760
Cdd:TIGR02169  990 ------------ELKEKRAKLEEERKAILERIEeyEKKKREVFMEA 1023
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1091-1390 4.39e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 4.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1091 EVQILEVQRAKAMVDKELEAEKLQKEQKI---------KEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTT 1161
Cdd:TIGR02169  199 QLERLRREREKAERYQALLKEKREYEGYEllkekealeRQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELN 278
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1162 LMNMEIADYERL-----MKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKE 1236
Cdd:TIGR02169  279 KKIKDLGEEEQLrvkekIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEE 358
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1237 LADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEkhkiHEHLKTSAEQHQRTLSAYRQRVTALQEESRAAKA 1316
Cdd:TIGR02169  359 YAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE----INELKRELDRLQEELQRLSEELADLNAAIAGIEA 434
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966982775  1317 EQATVTSEFESYKVRVHnvlKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQMNVSELQTLQSE 1390
Cdd:TIGR02169  435 KINELEEEKEDKALEIK---KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
452-742 4.95e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.39  E-value: 4.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  452 EKEKLTLMFEIQGLKEQCDNLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQAsDVHELQQKLRTAFT 531
Cdd:COG1196   224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA-EEYELLAELARLEQ 302
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  532 EKDALLETVNHLQGENEKLLSQQElvpELENTIKNLEEKngvyllsLSQRDTMLKELEAKINSLTEEKDDFINKLKNSYE 611
Cdd:COG1196   303 DIARLEERRRELEERLEELEEELA---ELEEELEELEEE-------LEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  612 EMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVK 691
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 966982775  692 SLYEENNKLSSEKKQLSRDLEVFLSQKNDVILKEHITELEKKLQLMVEERD 742
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
984-1414 7.67e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 7.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  984 KELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKERANnFEHHVEDLTRQLrnst 1063
Cdd:COG4717    74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEA-LEAELAELPERL---- 148
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1064 lqcekinsdnEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQL 1143
Cdd:COG4717   149 ----------EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA 218
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1144 QktmQELELVKKDAQQTTLMNMEIADYERLMKELNQKLSnkNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKN 1223
Cdd:COG4717   219 Q---EELEELEEELEQLENELEAAALEERLKEARLLLLI--AAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLL 293
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1224 TKIKQLLVKTKKELADS------KQAETDHLILQASLKGELEASQQQVEVYKI-QLAEITSEKHKIHEHLKTsaEQHQRT 1296
Cdd:COG4717   294 AREKASLGKEAEELQALpaleelEEEELEELLAALGLPPDLSPEELLELLDRIeELQELLREAEELEEELQL--EELEQE 371
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1297 LSAYRQRVTALQEESRAAKAEQAtvtSEFESYKVRVhNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNN 1376
Cdd:COG4717   372 IAALLAEAGVEDEEELRAALEQA---EEYQELKEEL-EELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEE 447
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 966982775 1377 LQMNVSELQTLQSEHDTLLERHN--KMLQETVSKEAELRE 1414
Cdd:COG4717   448 LEELREELAELEAELEQLEEDGElaELLQELEELKAELRE 487
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
592-1234 8.02e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.32  E-value: 8.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   592 INSLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEK 671
Cdd:TIGR04523   28 ANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSK 107
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   672 LMVQMKVLSEDKEVLSAEVKSLYEENN-------KLSSEKKQLSRDLEVFLSQKNDviLKEHITELEKKLQLMVEERDNL 744
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKenkknidKFLTEIKKKEKELEKLNNKYND--LKKQKEELENELNLLEKEKLNI 185
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   745 NKLLENEQVQKLfvktQLYGFLKDMGSEVSEDGEEKDVVNILQAVSESLAKINEEKCNLVFQCDKKVFELEKEIKCLQEE 824
Cdd:TIGR04523  186 QKNIDKIKNKLL----KLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDE 261
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   825 SVVQCEELKSLLRDYEQEKVL---LRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCNKNEIHNEK 901
Cdd:TIGR04523  262 QNKIKKQLSEKQKELEQNNKKikeLEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLN 341
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   902 EKCSikeheNLKPLLEQKESELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIKLVAVK 981
Cdd:TIGR04523  342 EQIS-----QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKK 416
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   982 AKKELDSSRKETQTVREELESLRSEKDQLSASMRDLiqaAESYKNLLLEYEKQSEQLDVEKERANNFEHHVEDLTRQLRN 1061
Cdd:TIGR04523  417 LQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVK---ELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKS 493
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1062 STLQCEKINSDNEDLLARIETLQSNAKLLEVQIlevqrakamvdKELEAEKLQKEQKIKEHATTVNELEEL--QVQLQKE 1139
Cdd:TIGR04523  494 KEKELKKLNEEKKELEEKVKDLTKKISSLKEKI-----------EKLESEKKEKESKISDLEDELNKDDFElkKENLEKE 562
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1140 KKQLQKTMQELELVKKDAQQTTLMNMEIAD-YERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQ 1218
Cdd:TIGR04523  563 IDEKNKEIEELKQTQKSLKKKQEEKQELIDqKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNK 642
                          650
                   ....*....|....*.
gi 966982775  1219 YEEKNTKIKQLLVKTK 1234
Cdd:TIGR04523  643 LKQEVKQIKETIKEIR 658
PRK11281 PRK11281
mechanosensitive channel MscK;
1074-1318 8.32e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 8.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1074 EDLLARIETLQSNaKLLEVQilevqraKAMVDKELEA--EKLQKEQKIKEhattvnELEELQVQLQKEKKQLQKTMQELE 1151
Cdd:PRK11281   39 ADVQAQLDALNKQ-KLLEAE-------DKLVQQDLEQtlALLDKIDRQKE------ETEQLKQQLAQAPAKLRQAQAELE 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1152 LVKKDAQQTTLMNMEIADYERLMKELNQKLSNKNNKIEDL----EQEIKIQKQKqETLQEEITSLQSSVQQyeekntkIK 1227
Cdd:PRK11281  105 ALKDDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLaeynSQLVSLQTQP-ERAQAALYANSQRLQQ-------IR 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1228 QLLVKTK---KELADSKQ----AETDHLILQASL-KGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQ-HQRTLS 1298
Cdd:PRK11281  177 NLLKGGKvggKALRPSQRvllqAEQALLNAQNDLqRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAiNSKRLT 256
                         250       260
                  ....*....|....*....|
gi 966982775 1299 AYRQRVTALQEESRAAKAEQ 1318
Cdd:PRK11281  257 LSEKTVQEAQSQDEAARIQA 276
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
451-740 8.99e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 8.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   451 SEKEKLTLMFE-IQGLKEQCDNLQQEKQEAILNYESLREIMEILQTELGEsagkISQEFESMKQQQASDVHELQQKLRTA 529
Cdd:TIGR02169  671 SEPAELQRLRErLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGE----IEKEIEQLEQEEEKLKERLEELEEDL 746
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   530 FTEKDALLETVNHLQGENEKLLSQQELVPELENTIKNLEEkngvyllslSQRDTMLKELEAKINSLTEEKDDFINKLKNS 609
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA---------RLSHSRIPEIQAELSKLEEEVSRIEARLREI 817
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   610 YEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAE 689
Cdd:TIGR02169  818 EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ 897
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 966982775   690 VKSLYEENNKLSSEKKQLSRDLEVFLSQKNdvILKEHITELEKKLQLMVEE 740
Cdd:TIGR02169  898 LRELERKIEELEAQIEKKRKRLSELKAKLE--ALEEELSEIEDPKGEDEEI 946
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
115-866 9.38e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 9.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   115 KMEDAHKELEQSHINyVKEIENLKNELMAVRAKYSEDKAN------LQKELEEAmnKQLELSEQLKFQNNSEDNVKKLQE 188
Cdd:TIGR02169  171 KKEKALEELEEVEEN-IERLDLIIDEKRQQLERLRREREKaeryqaLLKEKREY--EGYELLKEKEALERQKEAIERQLA 247
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   189 EIEKIRPAFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIhQEEVKELMCQIEASAKE 268
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERS-IAEKERELEDAEERLAK 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   269 HETEINKLNELKENLVKQCEaSEKNIQEKYECELENLRKATSNANQDNQMCSLLFQEnTFVEQVvnEKVKHLEDTLKELE 348
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIE-EERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE-TRDELK--DYREKLEKLKREIN 402
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   349 SqhsiLKDEVTYMNNLKLKLEMDAQHIKDEFfherEDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCcTVEQHNKE 428
Cdd:TIGR02169  403 E----LKRELDRLQEELQRLSEELADLNAAI----AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS-KYEQELYD 473
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   429 VQSLKEQHQKEISELNETfLSDSEKEKLTLMFEIQGLKEQCDNLQQEKQEAILNYESLREIMEILQTELGESAGK----- 503
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRE-LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNrlnnv 552
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   504 -------ISQEFESMKQQQAS------------------------------DVHELQQKLRTAFTE--KDAL----LETV 540
Cdd:TIGR02169  553 vveddavAKEAIELLKRRKAGratflplnkmrderrdlsilsedgvigfavDLVEFDPKYEPAFKYvfGDTLvvedIEAA 632
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   541 NHLQGENEKLLSQQELVPELENTIKNLEEKNGVYLLSLSQRDTmLKELEAKINSLTEEKDDFINKLKNSYEEMDNFHKKC 620
Cdd:TIGR02169  633 RRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAE-LQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL 711
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   621 EREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLY-EENNK 699
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEaRLSHS 791
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   700 LSSEKKQLSRDLEVFLSQkndviLKEHITELEKKLQLMVEERDNLNKLLENEQVQKLFVKTQLygflkdmgsevsedGEE 779
Cdd:TIGR02169  792 RIPEIQAELSKLEEEVSR-----IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQI--------------KSI 852
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   780 KDVVNILQAVSESLAKINEEKCNLVFQCDKKVFELEKEIKCLQEesvvQCEELKSLLRDYEQEKVLLRKELEEIQSEKEA 859
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA----QLRELERKIEELEAQIEKKRKRLSELKAKLEA 928

                   ....*..
gi 966982775   860 LQSDLLE 866
Cdd:TIGR02169  929 LEEELSE 935
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
691-1464 1.04e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.42  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   691 KSLYEENNKLSSEKKQLSRDLEvfLSQKNDVILKEHITELEKKLQLMVEERDNLNKLLENEqvqklfvktqlygflkdmg 770
Cdd:pfam15921   78 RVLEEYSHQVKDLQRRLNESNE--LHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRE------------------- 136
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   771 sevseDGEEKDVVNILQAVSESLAKINEEKCNLVFQCDKKVFELEKEIkcLQEESVVQceELKSLLRDYEQEK------- 843
Cdd:pfam15921  137 -----SQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMM--LSHEGVLQ--EIRSILVDFEEASgkkiyeh 207
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   844 ------------VLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNlliQVEEVSQTcnkneiHNEKEKCSIKEHEN 911
Cdd:pfam15921  208 dsmstmhfrslgSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQN---KIELLLQQ------HQDRIEQLISEHEV 278
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   912 LKPLLEQKESELRdtraelillkdSLAKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIKLVAVKAKKELDSSRK 991
Cdd:pfam15921  279 EITGLTEKASSAR-----------SQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEEL 347
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   992 ETQTV--REELESLRSEKDQLSASMRDLiqaAESYKNLLLEYEKQSEQLDVEKERANNFEHH-------VEDLTRQLRNS 1062
Cdd:pfam15921  348 EKQLVlaNSELTEARTERDQFSQESGNL---DDQLQKLLADLHKREKELSLEKEQNKRLWDRdtgnsitIDHLRRELDDR 424
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1063 TLQCEKINS-----------DNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDK---ELEAEKLQKEQKIKEHATTVNE 1128
Cdd:pfam15921  425 NMEVQRLEAllkamksecqgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKvveELTAKKMTLESSERTVSDLTAS 504
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1129 LEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEE 1208
Cdd:pfam15921  505 LQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRT 584
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1209 ITSLQSSVQQYEeKNTKIKQLLVKTKKELADSKQAETDhlilqaslkgELEASQQQVEVYKIQLAEITSEKHKIHEHLKT 1288
Cdd:pfam15921  585 AGAMQVEKAQLE-KEINDRRLELQEFKILKDKKDAKIR----------ELEARVSDLELEKVKLVNAGSERLRAVKDIKQ 653
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1289 SAEQhqrtlsayrqrvtaLQEESRAAKAEQATVTSEFESYKvrvhnvlKQQKNKSmsqaetegakqerEHLEMLIDQLKI 1368
Cdd:pfam15921  654 ERDQ--------------LLNEVKTSRNELNSLSEDYEVLK-------RNFRNKS-------------EEMETTTNKLKM 699
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1369 KLQDSQNNLQMNVSELQTLQSEHDTLLERHNKMLQETVSKEAE----------LREKLCSIQSENMMMKSEHTQtVSQLT 1438
Cdd:pfam15921  700 QLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQidalqskiqfLEEAMTNANKEKHFLKEEKNK-LSQEL 778
                          810       820
                   ....*....|....*....|....*.
gi 966982775  1439 SQNEVLRNSFRDQVRHLQEEHRKTVE 1464
Cdd:pfam15921  779 STVATEKNKMAGELEVLRSQERRLKE 804
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1079-1278 1.25e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 1.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1079 RIETLQSNAKLLEvQILEV-QRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDA 1157
Cdd:COG4913   243 ALEDAREQIELLE-PIRELaERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDAL 321
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1158 QQttlmnmEIADYERlmkelnQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKEL 1237
Cdd:COG4913   322 RE------ELDELEA------QIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 966982775 1238 ADSKQAETDHLILQASLKGELEASQQQVevyKIQLAEITSE 1278
Cdd:COG4913   390 AALLEALEEELEALEEALAEAEAALRDL---RRELRELEAE 427
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
433-1157 1.41e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 1.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   433 KEQHQKEISELnETFLSDSEKEKLTLMFEIQGLKEQCDNLQQEKQEAILNYESL-REIMEILQTELGESAGKISQeFESM 511
Cdd:TIGR02169  232 KEALERQKEAI-ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIAS-LERS 309
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   512 KQQQASDVHELQQKLRTAFTEKDALLETVNHLQGENEkllSQQELVPELENTIKNLEEKNGVYLLSLSQRDTMLKELEAK 591
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIE---EERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   592 INSLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEK 671
Cdd:TIGR02169  387 LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   672 LMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQL------SRDLEVFLSQKNDVIL----------KEHITELE---- 731
Cdd:TIGR02169  467 YEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASeervrgGRAVEEVLKASIQGVHgtvaqlgsvgERYATAIEvaag 546
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   732 KKLQLMVEERDN---------------------LNKLLENEQVQKLFVKTQLYGFLKD---------------------- 768
Cdd:TIGR02169  547 NRLNNVVVEDDAvakeaiellkrrkagratflpLNKMRDERRDLSILSEDGVIGFAVDlvefdpkyepafkyvfgdtlvv 626
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   769 ---------MGSE--VSEDGE--EKDVVNILQAVSESLAKINE-EKCNLVFQCDKKVFELEKEIKCLQEESvvqcEELKS 834
Cdd:TIGR02169  627 edieaarrlMGKYrmVTLEGElfEKSGAMTGGSRAPRGGILFSrSEPAELQRLRERLEGLKRELSSLQSEL----RRIEN 702
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   835 LLRDYEQEKVLLRKELEEIQSEKEALQSDLlemknANEKTRLENQNLLIQVEEVSQTCNKNEI-HNEKEKCSIKEH-ENL 912
Cdd:TIGR02169  703 RLDELSQELSDASRKIGEIEKEIEQLEQEE-----EKLKERLEELEEDLSSLEQEIENVKSELkELEARIEELEEDlHKL 777
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   913 KPLLEQKESELRDTR-----AELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIKLVAVKAKKELD 987
Cdd:TIGR02169  778 EEALNDLEARLSHSRipeiqAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE 857
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   988 SSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKERAnnfEHHVEDLTRQLRNSTLQce 1067
Cdd:TIGR02169  858 NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK---RKRLSELKAKLEALEEE-- 932
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1068 kiNSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKeLEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTM 1147
Cdd:TIGR02169  933 --LSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRA-LEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERI 1009
                          810
                   ....*....|
gi 966982775  1148 QELELVKKDA 1157
Cdd:TIGR02169 1010 EEYEKKKREV 1019
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1106-1483 1.41e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 1.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1106 KELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQqttlmnmeIADYERLMKELNQKLSNKN 1185
Cdd:COG4717    74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ--------LLPLYQELEALEAELAELP 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1186 NKIEDLEQEIkiqkQKQETLQEEITSLQSSVQQYEEK-NTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQ 1264
Cdd:COG4717   146 ERLEELEERL----EELRELEEELEELEAELAELQEElEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEE 221
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1265 VEVYKIQLAEITSEKHKIHEHLKTSAEQHQR-------TLSAYRQRVTALQEESRAAKAEQATVTSEFESYKVRVHNVLK 1337
Cdd:COG4717   222 LEELEEELEQLENELEAAALEERLKEARLLLliaaallALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLG 301
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1338 QQKNKSMSQAETEGAKQERehLEMLIDQLKIKLQDSQNNLQMNVSELQTLQSEHDTLLERHNKMLQET------------ 1405
Cdd:COG4717   302 KEAEELQALPALEELEEEE--LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEEleqeiaallaea 379
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1406 -VSKEAELREKLcSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRD-----------QVRHLQEEHRKTVETLQQQLSRV 1473
Cdd:COG4717   380 gVEDEEELRAAL-EQAEEYQELKEELEELEEQLEELLGELEELLEAldeeeleeeleELEEELEELEEELEELREELAEL 458
                         410
                  ....*....|
gi 966982775 1474 EAQLFQLKNE 1483
Cdd:COG4717   459 EAELEQLEED 468
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
1166-1355 1.60e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.98  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1166 EIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQssvQQYEEKNTKIKQLLVKTKKELADSKQAEt 1245
Cdd:COG3883    31 ELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAE---AEIEERREELGERARALYRSGGSVSYLD- 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1246 dhLILQAS----LKGELEASQQQVEVYKIQLAEITSEKHKIhEHLKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATV 1321
Cdd:COG3883   107 --VLLGSEsfsdFLDRLSALSKIADADADLLEELKADKAEL-EAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEAL 183
                         170       180       190
                  ....*....|....*....|....*....|....
gi 966982775 1322 TSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQE 1355
Cdd:COG3883   184 LAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
100-735 1.62e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.55  E-value: 1.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   100 KENIKMKQEVEDSVTKMEDAHKELEQSHINYVKEIENLKNELMAVRAKYSEdkanLQKELEEAMNKQLELSEQLKFQNNS 179
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYND----LKKQKEELENELNLLEKEKLNIQKN 188
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   180 EDNVKKLQEEIEKIRPAFEEQIlYLQKQLDATTDEKKETVTQLQNIIEANSQHYQK---NINSLQEELLQLKAIHQEEVK 256
Cdd:TIGR04523  189 IDKIKNKLLKLELLLSNLKKKI-QKNKSLESQISELKKQNNQLKDNIEKKQQEINEkttEISNTQTQLNQLKDEQNKIKK 267
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   257 ELmcqiEASAKEHETEINKLNELKENLVKQCEASEKNIQEKYECELENLRKATSNANQDNQMCSLLFQENTFVEQVVNEK 336
Cdd:TIGR04523  268 QL----SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQ 343
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   337 VKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFH---EREDLEFKINELLLAKEEQGCVIEKLKSELAG 413
Cdd:TIGR04523  344 ISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNlesQINDLESKIQNQEKLNQQKDEQIKKLQQEKEL 423
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   414 LNKQ---FCCTVEQHNKEVQSLKEQ-HQKEISELNETFLSDSEKEKL-TLMFEIQGLKEQCDNLQQEKQEAILNYESLRE 488
Cdd:TIGR04523  424 LEKEierLKETIIKNNSEIKDLTNQdSVKELIIKNLDNTRESLETQLkVLSRSINKIKQNLEQKQKELKSKEKELKKLNE 503
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   489 IMEILQTELGESAGKISqEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQQELVpELENTIKNLE 568
Cdd:TIGR04523  504 EKKELEEKVKDLTKKIS-SLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIE-ELKQTQKSLK 581
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   569 EKNgvyllslSQRDTMLKELEAKINSLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKV 648
Cdd:TIGR04523  582 KKQ-------EEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   649 NELTGGLEETLKEKDQNDQKLEKLMVQMKV-LSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKNDVILKEHI 727
Cdd:TIGR04523  655 KEIRNKWPEIIKKIKESKTKIDDIIELMKDwLKELSLHYKKYITRMIRIKDLPKLEEKYKEIEKELKKLDEFSKELENII 734

                   ....*...
gi 966982775   728 TELEKKLQ 735
Cdd:TIGR04523  735 KNFNKKFD 742
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1106-1303 1.65e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1106 KELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKtMQELELVKKDAQQTTlmnmeiADYERLMKELnQKLSNKN 1185
Cdd:COG4913   613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQR-LAEYSWDEIDVASAE------REIAELEAEL-ERLDASS 684
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1186 NKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLL--VKTKKELADSKQAETDHLILQASLKGELEAsqq 1263
Cdd:COG4913   685 DDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELdeLQDRLEAAEDLARLELRALLEERFAAALGD--- 761
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 966982775 1264 qvEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYRQR 1303
Cdd:COG4913   762 --AVERELRENLEERIDALRARLNRAEEELERAMRAFNRE 799
PTZ00121 PTZ00121
MAEBL; Provisional
739-1312 2.30e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.29  E-value: 2.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  739 EERDNLNKLLENEQVQKlFVKTQLYGFLKDMGSEVSEDGEEKDVVNILQAVSESLAKINEEKCNLVFQCDKKVFELEK-- 816
Cdd:PTZ00121 1240 EEAKKAEEERNNEEIRK-FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKad 1318
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  817 EIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTcnkNE 896
Cdd:PTZ00121 1319 EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA---DE 1395
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  897 IHNEKEKCSIKEHENLKPLLEQKESELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIK 976
Cdd:PTZ00121 1396 AKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEA 1475
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  977 LVAVKAKKELDSSRKETQTVREELESLR--SEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDV--EKERANNFEHHV 1052
Cdd:PTZ00121 1476 KKKAEEAKKADEAKKKAEEAKKKADEAKkaAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKaeEKKKADELKKAE 1555
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1053 EDLTRQLRNSTLQCEKINSDNEDLLARIETLQsnaKLLEVQILEVQRAKAMvDKELEAEKLQKEQKIKEHATTVNELEEL 1132
Cdd:PTZ00121 1556 ELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK---KAEEARIEEVMKLYEE-EKKMKAEEAKKAEEAKIKAEELKKAEEE 1631
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1133 QVQLQKEKKQLQKTMQELELVKKDAQQTTLMNmeiadyerlmKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEitsl 1212
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKA----------AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKE---- 1697
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1213 qssvQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQ 1292
Cdd:PTZ00121 1698 ----AEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
                         570       580
                  ....*....|....*....|
gi 966982775 1293 HQRTLSAYRQRVTALQEESR 1312
Cdd:PTZ00121 1774 RKEKEAVIEEELDEEDEKRR 1793
46 PHA02562
endonuclease subunit; Provisional
1003-1255 2.77e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.78  E-value: 2.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1003 LRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKEraNNFEHHVE---DLTRQLRNSTLQCEKINSDNEDLLAR 1079
Cdd:PHA02562  179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQ--NKYDELVEeakTIKAEIEELTDELLNLVMDIEDPSAA 256
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1080 IETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQkeQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELvkkdaqq 1159
Cdd:PHA02562  257 LNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCT--QQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEE------- 327
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1160 ttLMNmEIADYERLMKELNQKLSNKNNKIEDLEQEIKiqkqkqeTLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELAD 1239
Cdd:PHA02562  328 --IMD-EFNEQSKKLLELKNKISTNKQSLITLVDKAK-------KVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSE 397
                         250
                  ....*....|....*.
gi 966982775 1240 SKQAETDHLILQASLK 1255
Cdd:PHA02562  398 LVKEKYHRGIVTDLLK 413
46 PHA02562
endonuclease subunit; Provisional
1162-1367 2.84e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.39  E-value: 2.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1162 LMNMEIADYERLMKELNQK----LSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKEL 1237
Cdd:PHA02562  192 HIQQQIKTYNKNIEEQRKKngenIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKI 271
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1238 AD----------------SKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHE------HLKTSAEQHQR 1295
Cdd:PHA02562  272 EQfqkvikmyekggvcptCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEqskkllELKNKISTNKQ 351
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966982775 1296 TLSAYRQRVTALQEESRAAKAEQATVTSEFESYkvrVHNVLKQQKNKSmsqaeteGAKQEREHLEMLIDQLK 1367
Cdd:PHA02562  352 SLITLVDKAKKVKAAIEELQAEFVDNAEELAKL---QDELDKIVKTKS-------ELVKEKYHRGIVTDLLK 413
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
131-479 2.93e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 2.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   131 VKEIENLKNELMAVRAKYSEDKANLQKELEEAMNKQLELSEQLKfqnNSEDNVKKLQEEIEKIRPAfeeqilylQKQLDA 210
Cdd:TIGR02169  697 LRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE---ELEEDLSSLEQEIENVKSE--------LKELEA 765
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   211 TTDEKKETVTQLQNIIEANSQHY-QKNINSLQEELLQLKAIHQEevkelmcqIEASAKEHETEINKLNELKENLvkqcea 289
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLsHSRIPEIQAELSKLEEEVSR--------IEARLREIEQKLNRLTLEKEYL------ 831
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   290 sEKNIQekyecELENLRKATSnaNQDNQMCSLLFQENTFVEQvVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLE 369
Cdd:TIGR02169  832 -EKEIQ-----ELQEQRIDLK--EQIKSIEKEIENLNGKKEE-LEEELEELEAALRDLESRLGDLKKERDELEAQLRELE 902
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   370 MDAQHIKDEFFHEREDLEfKINELLLAKEEQGCVIEKLKSEL---------AGLNKQFCCTVEQhnkEVQSLKEQHQKEI 440
Cdd:TIGR02169  903 RKIEELEAQIEKKRKRLS-ELKAKLEALEEELSEIEDPKGEDeeipeeelsLEDVQAELQRVEE---EIRALEPVNMLAI 978
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 966982775   441 SELNETF--LSDSEKEKLTLMFEIQGLKEQCDNLQQEKQEA 479
Cdd:TIGR02169  979 QEYEEVLkrLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
mukB PRK04863
chromosome partition protein MukB;
1127-1476 3.26e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 3.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1127 NELEELQVQLQKEKKQLQKT---MQELELVKKDAQQTTLMNMEIA---DYERLMKELNQKLSNKNNKIEDLEQEIKIQKQ 1200
Cdd:PRK04863  786 KRIEQLRAEREELAERYATLsfdVQKLQRLHQAFSRFIGSHLAVAfeaDPEAELRQLNRRRVELERALADHESQEQQQRS 865
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1201 KQETLQEEITSLQSSVQQyeekntkIKQLLVKTKKELADSKQAEtdhliLQASLKGELEASQQQVEVYKI--QLAEITSE 1278
Cdd:PRK04863  866 QLEQAKEGLSALNRLLPR-------LNLLADETLADRVEEIREQ-----LDEAEEAKRFVQQHGNALAQLepIVSVLQSD 933
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1279 KHKiHEHLKTSAEQHQRTLSAYRQRVTALQE--ESRAAKA-EQAtvtsefesykvrvhnvlkqQKNKSMSQAETEGAKQE 1355
Cdd:PRK04863  934 PEQ-FEQLKQDYQQAQQTQRDAKQQAFALTEvvQRRAHFSyEDA-------------------AEMLAKNSDLNEKLRQR 993
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1356 REHLEMLIDQLKIKLQDSQNNLQMNVSELQTLQSEHDTLLERHNKMLQE----TVSKEAELREKLCSIQSENMMMKSEHT 1431
Cdd:PRK04863  994 LEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQElqdlGVPADSGAEERARARRDELHARLSANR 1073
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 966982775 1432 QTVSQLTSQnevlRNSFRDQVRHLQEEHRKTVETLQQQLSRVEAQ 1476
Cdd:PRK04863 1074 SRRNQLEKQ----LTFCEAEMDNLTKKLRKLERDYHEMREQVVNA 1114
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
1111-1324 3.45e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 45.30  E-value: 3.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1111 EKLQKEQKIkehattvnELEELQVQLQKEK-----KQLQKTMQELELVKKDAQ-----QTTLMNMEIADYERLMKELNQK 1180
Cdd:PRK05771   23 EALHELGVV--------HIEDLKEELSNERlrklrSLLTKLSEALDKLRSYLPklnplREEKKKVSVKSLEELIKDVEEE 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1181 LSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQ-----SSVQQYEEKNTKIKQLLVKTKKELADSKQAETD--HLILQAS 1253
Cdd:PRK05771   95 LEKIEKEIKELEEEISELENEIKELEQEIERLEpwgnfDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESDveNVEYIST 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1254 LKG-------------------------------ELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYRQ 1302
Cdd:PRK05771  175 DKGyvyvvvvvlkelsdeveeelkklgferleleEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYE 254
                         250       260
                  ....*....|....*....|..
gi 966982775 1303 rvtALQEESRAAKAEQATVTSE 1324
Cdd:PRK05771  255 ---YLEIELERAEALSKFLKTD 273
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
101-1187 4.05e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 45.43  E-value: 4.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   101 ENIKMKQEVEDSVTKMEDAHKELEQSHINYVK----EIENLKNELMAV-----RAKYSEDKANLQKELEEAMNKQLELSE 171
Cdd:TIGR01612  690 DNTEDKAKLDDLKSKIDKEYDKIQNMETATVElhlsNIENKKNELLDIiveikKHIHGEINKDLNKILEDFKNKEKELSN 769
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   172 QLKFQNNSEDNVKKLQEEIEKIRPAFEEQIL------------YLQ-----KQLDATTDEKKETVTQLQNIIEAN----- 229
Cdd:TIGR01612  770 KINDYAKEKDELNKYKSKISEIKNHYNDQINidnikdedakqnYDKskeyiKTISIKEDEIFKIINEMKFMKDDFlnkvd 849
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   230 -----SQHYQKNINSLQEELLQLKAIHQEEV---------------KELMCQIEASAKEHETEINKLNELKENLvKQCEA 289
Cdd:TIGR01612  850 kfinfENNCKEKIDSEHEQFAELTNKIKAEIsddklndyekkfndsKSLINEINKSIEEEYQNINTLKKVDEYI-KICEN 928
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   290 SEKNIQEKYECELENLRKATSNANQDNQMCSLLFQENTFVEQVVNEKVKHLEDTLKE--LESQHSILKDEVTYMNNLKLK 367
Cdd:TIGR01612  929 TKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKDasLNDYEAKNNELIKYFNDLKAN 1008
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   368 LEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIE-----KLKSELAGLNKQFCCTVEQHNKEVQSLKEQHQKEISE 442
Cdd:TIGR01612 1009 LGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEiaihtSIYNIIDEIEKEIGKNIELLNKEILEEAEINITNFNE 1088
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   443 LNE-----TFLSDSEKEKLTLMFEIQGLKEQCDNLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFE-SMKQQQA 516
Cdd:TIGR01612 1089 IKEklkhyNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADkAISNDDP 1168
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   517 SDVHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQQELVPELENTikNLEEKNGVYLLSLSQRD-------TMLKELE 589
Cdd:TIGR01612 1169 EEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEVKGI--NLSYGKNLGKLFLEKIDeekkkseHMIKAME 1246
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   590 AKINSLTEEKDDF----------------INKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQYNSElEQKVNELTG 653
Cdd:TIGR01612 1247 AYIEDLDEIKEKSpeienemgiemdikaeMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIEDFSE-ESDINDIKK 1325
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   654 GLEETLKEKDQNDQKLEKLMVQMK------VLSEDKEVLS--AEVKSLYEENNKlsSEKKQLSRDLEVFLSQKNDVILKE 725
Cdd:TIGR01612 1326 ELQKNLLDAQKHNSDINLYLNEIAniynilKLNKIKKIIDevKEYTKEIEENNK--NIKDELDKSEKLIKKIKDDINLEE 1403
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   726 hiteLEKKLQLMVEERDnLNKLLENEQVQKLFV---KTQLYGFLKDmgsevsEDGEEKDVV----NILQAVSESLAKINE 798
Cdd:TIGR01612 1404 ----CKSKIESTLDDKD-IDECIKKIKELKNHIlseESNIDTYFKN------ADENNENVLllfkNIEMADNKSQHILKI 1472
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   799 EKCNLVFQCDKKVFELEKEI------KCLQEESVVQCEELKSLLRDYEQE-KVLLRKELEeiqsekealqsdlLEMKNAN 871
Cdd:TIGR01612 1473 KKDNATNDHDFNINELKEHIdkskgcKDEADKNAKAIEKNKELFEQYKKDvTELLNKYSA-------------LAIKNKF 1539
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   872 EKTRLENQnllIQVEEVSQTCNKNEIHNEKEKCSIKEHENLKPLLEQKESELRDTRAELILLKDSLAkspSVQNDLLssv 951
Cdd:TIGR01612 1540 AKTKKDSE---IIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLE---NFENKFL--- 1610
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   952 KELEEKLENLEKEGKEKEEKINKIKLVAVKAKKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQA---AESYKNLL 1028
Cdd:TIGR01612 1611 KISDIKKKINDCLKETESIEKKISSFSIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELdseIEKIEIDV 1690
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1029 LEYEKQSEQLDVEK--ERANNFEHHVEDlTRQLRNSTLQCEKINSDNEDLlariETLQSNAKLLEVQI-LEVQRAKAMVD 1105
Cdd:TIGR01612 1691 DQHKKNYEIGIIEKikEIAIANKEEIES-IKELIEPTIENLISSFNTNDL----EGIDPNEKLEEYNTeIGDIYEEFIEL 1765
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1106 KELEAEKLQKeqkIKEHATTVNELEELQVQLQKEkkqlqkTMQELELVKKdaQQTTLMNMEIADYERLMKELNQKLSNKN 1185
Cdd:TIGR01612 1766 YNIIAGCLET---VSKEPITYDEIKNTRINAQNE------FLKIIEIEKK--SKSYLDDIEAKEFDRIINHFKKKLDHVN 1834

                   ..
gi 966982775  1186 NK 1187
Cdd:TIGR01612 1835 DK 1836
CC149 pfam09789
Coiled-coil domain-containing protein 149-A; Members of this family have been annotated as ...
983-1219 4.12e-04

Coiled-coil domain-containing protein 149-A; Members of this family have been annotated as being coiled-coil domain-containing protein 149, however they currently have no known function.


Pssm-ID: 462902 [Multi-domain]  Cd Length: 314  Bit Score: 44.24  E-value: 4.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   983 KKELDSSRKETQTVREELESLRSEKDQLSAsmrdliqAAESYKNLLLEYEKQSEQLDVEKERANNFEHHVEDLTRQLRNS 1062
Cdd:pfam09789    1 KRKLQSKVEALLILSKELEKCRQERDQYKL-------MAEQLQERYQGLKKQLRELKAGNNDFKPDDREQVNLIQLLRDS 73
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1063 TLQCEKINSDNEDLLARIETLQSNAKLLEVQIlEVQRAKAMVDKELEAEKLQKEQKIKehatTVNELEELQVQLQKEKKQ 1142
Cdd:pfam09789   74 REQNKCLRLEVEELRQKLNEAQGDIKLLREQI-ARQRLGGPDEGSISTRHFPLHEREE----LVKQLEKLRKKCQQLERD 148
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1143 LQKTMQELE--LVKKDAQQTTlmnmeiadYERLMKELNQKLSNKNNKIEDLEQ---EIKIQKQKQETLQEEITSLQSSVQ 1217
Cdd:pfam09789  149 LQSVLDEKEelETERDAYKCK--------AHRLNHELNYILGGDESRIVDIDAlimENRYLQERLKQLEEEKELAKQTLS 220

                   ..
gi 966982775  1218 QY 1219
Cdd:pfam09789  221 KY 222
COG5022 COG5022
Myosin heavy chain [General function prediction only];
87-350 4.12e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.45  E-value: 4.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   87 EKAETEQQCLSLKKENIkmkqeVEDSVTKMEDAHKELEQSHINyVKEIENLKNELMAVRAKYSEDKANLQKeleeamnkq 166
Cdd:COG5022   853 RSLKAKKRFSLLKKETI-----YLQSAQRVELAERQLQELKID-VKSISSLKLVNLELESEIIELKKSLSS--------- 917
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  167 lELSEQLKFQNNSEDNVKKLQEEIEKIRPAFEEQILYLQKQLDATTDEK-KETVTQLQNIIEANSQHYQKNINSLqEELL 245
Cdd:COG5022   918 -DLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKlKETSEEYEDLLKKSTILVREGNKAN-SELK 995
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  246 QLKAIHQEEVKELMcQIEASAKEHETEINKLNELKENLVKQCEASEKNIQEKYECELENLRKATSNANQDNQMCSLLFQE 325
Cdd:COG5022   996 NFKKELAELSKQYG-ALQESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRE 1074
                         250       260
                  ....*....|....*....|....*...
gi 966982775  326 NTFVEQV---VNEKVKHLEDTLKELESQ 350
Cdd:COG5022  1075 NSLLDDKqlyQLESTENLLKTINVKDLE 1102
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
994-1151 4.41e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.76  E-value: 4.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  994 QTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEKERAnnfEHHVEDLTRQLRNSTLQCEKINSDN 1073
Cdd:COG1579    13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRL---ELEIEEVEARIKKYEEQLGNVRNNK 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1074 E--DLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELE 1151
Cdd:COG1579    90 EyeALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELA 169
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
979-1366 4.54e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.33  E-value: 4.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  979 AVKAKKELDSSRKETQTVREELESLRSEKDQLSASMRDL---IQAAESYKNLLLEYEKQSEQLDvekeranNFEHHVEDL 1055
Cdd:COG3096   287 ALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLeqdYQAASDHLNLVQTALRQQEKIE-------RYQEDLEEL 359
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1056 TRQLRNSTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAkamVDkELEAEKLQKEQKIK--EHATTVNELEEL- 1132
Cdd:COG3096   360 TERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQA---LD-VQQTRAIQYQQAVQalEKARALCGLPDLt 435
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1133 -------QVQLQKEKKQLQKTMQELElvkkdaQQTTLMNMEIADYERLMkELNQKLSNKNNK-------IEDLEQ--EIK 1196
Cdd:COG3096   436 penaedyLAAFRAKEQQATEEVLELE------QKLSVADAARRQFEKAY-ELVCKIAGEVERsqawqtaRELLRRyrSQQ 508
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1197 IQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETdhliLQASLKGELEASQQQVEVYKIQLAEIT 1276
Cdd:COG3096   509 ALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEE----LLAELEAQLEELEEQAAEAVEQRSELR 584
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1277 SEKHKIHEHLKTSAEQHQRTLSAyRQRVTALQEESRAAKAEQATVTSEFEsykvrvhNVLKQQKNKSMSQAETEgakQER 1356
Cdd:COG3096   585 QQLEQLRARIKELAARAPAWLAA-QDALERLREQSGEALADSQEVTAAMQ-------QLLEREREATVERDELA---ARK 653
                         410
                  ....*....|
gi 966982775 1357 EHLEMLIDQL 1366
Cdd:COG3096   654 QALESQIERL 663
COG5022 COG5022
Myosin heavy chain [General function prediction only];
415-817 5.05e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.07  E-value: 5.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  415 NKQFCCTVEQHNKEVQSLKEQHQKEISELNETFLS-DSEKEKLTLMFEIQglkeqcdNLQQEKQEAILNYESlreimEIL 493
Cdd:COG5022   780 GFRLRRLVDYELKWRLFIKLQPLLSLLGSRKEYRSyLACIIKLQKTIKRE-------KKLRETEEVEFSLKA-----EVL 847
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  494 QTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQqelVPELENTIKNLEEKNgv 573
Cdd:COG5022   848 IQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKSISSLKLVNLELESE---IIELKKSLSSDLIEN-- 922
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  574 yLLSLSQRDTMLKELEAKINSLTE-EKDDFINKLKNSY-EEMDNFHKKCEREERLILELGKKVEQTTQYNSELEQKVNEL 651
Cdd:COG5022   923 -LEFKTELIARLKKLLNNIDLEEGpSIEYVKLPELNKLhEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKEL 1001
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  652 TGGLEEtlKEKDQNDQKleklmvqmkvLSEDKEVLSAEVKSLYeenNKLSSEKKQLSRDLEVfLSQKNDVILKEHITELE 731
Cdd:COG5022  1002 AELSKQ--YGALQESTK----------QLKELPVEVAELQSAS---KIISSESTELSILKPL-QKLKGLLLLENNQLQAR 1065
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  732 -KKLQLMVEERDNLNKLLENEQVQKLFVKTQLYGFLKdMGSEVSEDGEEKDVVNILQAVSESLAKINEEKCNLVFQCDKK 810
Cdd:COG5022  1066 yKALKLRRENSLLDDKQLYQLESTENLLKTINVKDLE-VTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEP 1144

                  ....*..
gi 966982775  811 VFELEKE 817
Cdd:COG5022  1145 VFQKLSV 1151
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
603-1346 7.78e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.44  E-value: 7.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   603 INKLKNSYEEMDNFHKKCEREERLILELGKKVEQTT-QYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSE 681
Cdd:pfam12128  250 FNTLESAELRLSHLHFGYKSDETLIASRQEERQETSaELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALED 329
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   682 DKEV-LSAEVKSLYEENNKL---SSEKKQLSRDLEVFLSQKNDVILKEHITELEKKLQLmVEERDNLNKLLENEQVQKlf 757
Cdd:pfam12128  330 QHGAfLDADIETAAADQEQLpswQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQN-NRDIAGIKDKLAKIREAR-- 406
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   758 vktqlygflkDMGSEVSEDGEEKDVVNILQAVSESLAKINEEKcnlvfqcdkKVFELEKEIKCLQEESVVQCEELKSLLR 837
Cdd:pfam12128  407 ----------DRQLAVAEDDLQALESELREQLEAGKLEFNEEE---------YRLKSRLGELKLRLNQATATPELLLQLE 467
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   838 DYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCNKNEIHNEKEKCSIKEH-ENLKPLL 916
Cdd:pfam12128  468 NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFlRKEAPDW 547
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   917 EQKESELRDTraELILLKD---SLAKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINkiklvAVKAKKELDSSRKET 993
Cdd:pfam12128  548 EQSIGKVISP--ELLHRTDldpEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRER-----LDKAEEALQSAREKQ 620
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   994 QTVREELESLRSEKDQLSASMRDLIQAAESYKNLL--LEYEKQSEQLDVEKERANNFEHHVEDLT------RQLRNStLQ 1065
Cdd:pfam12128  621 AAAEEQLVQANGELEKASREETFARTALKNARLDLrrLFDEKQSEKDKKNKALAERKDSANERLNsleaqlKQLDKK-HQ 699
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1066 CEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQK 1145
Cdd:pfam12128  700 AWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRT 779
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1146 TMQELELVKKDAQqttlmnmEIADYERLMKE--------LNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQ 1217
Cdd:pfam12128  780 LERKIERIAVRRQ-------EVLRYFDWYQEtwlqrrprLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASE 852
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1218 QYEEKNTKIKQLLVKTKKELADSKQAETDhlilqASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRtl 1297
Cdd:pfam12128  853 KQQVRLSENLRGLRCEMSKLATLKEDANS-----EQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADHSG-- 925
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 966982775  1298 SAYRQRVTALQEESRAAKAEQATVTSEFESYKVR--VHNVLKQQKNKSMSQ 1346
Cdd:pfam12128  926 SGLAETWESLREEDHYQNDKGIRLLDYRKLVPYLeqWFDVRVPQSIMVLRE 976
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1042-1627 8.83e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 8.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1042 KERANNFEHHVEDLTRQLRNSTLQCEKINSDNE--DLLARIETLQSNAKLLEVQI--LEVQRAKAMVDKELEAEKL---- 1113
Cdd:PRK02224  168 RERASDARLGVERVLSDQRGSLDQLKAQIEEKEekDLHERLNGLESELAELDEEIerYEEQREQARETRDEADEVLeehe 247
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1114 QKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKE-LNQKLSNKNNKIEDLE 1192
Cdd:PRK02224  248 ERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEaVEARREELEDRDEELR 327
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1193 QEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQL 1272
Cdd:PRK02224  328 DRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDL 407
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1273 -------AEITSEKHKIHEHLkTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTSEfesykvRVHNVLKQQKNKSMS 1345
Cdd:PRK02224  408 gnaedflEELREERDELRERE-AELEATLRTARERVEEAEALLEAGKCPECGQPVEGSP------HVETIEEDRERVEEL 480
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1346 QAETEGAKQEREHLEMLIDQLK--IKLQDSQNNLQMNVSELQTLQSEHDTLLErhnkmlqETVSKEAELREKlcsiqsen 1423
Cdd:PRK02224  481 EAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERREDLEELIAERRETIE-------EKRERAEELRER-------- 545
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1424 mmmksehtqtVSQLTSQNEVLRNSFRDQvRHLQEEHRKTVETLQQQLSRVEAQLFQLKNEPTTRSPVSS-QQSLKNLRER 1502
Cdd:PRK02224  546 ----------AAELEAEAEEKREAAAEA-EEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADaEDEIERLREK 614
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1503 RntdlplldmhtvtrEEGEGMETTDTESVSSASTYTQSLEQLLNspetkfepplwhaEFTKEELVQKLSSTTKSADHLNG 1582
Cdd:PRK02224  615 R--------------EALAELNDERRERLAEKRERKRELEAEFD-------------EARIEEAREDKERAEEYLEQVEE 667
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*.
gi 966982775 1583 LLRETEATNAILMEQIKLLKSEIRRLERNQEREKSAAN-LEYLKNV 1627
Cdd:PRK02224  668 KLDELREERDDLQAEIGAVENELEELEELRERREALENrVEALEAL 713
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
335-532 8.87e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 8.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  335 EKVKHLEDTLKELESQHSILKDEVTymnnlKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEqgcvIEKLKSELAGL 414
Cdd:COG4913   610 AKLAALEAELAELEEELAEAEERLE-----ALEAELDALQERREALQRLAEYSWDEIDVASAERE----IAELEAELERL 680
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  415 nkqfcctvEQHNKEVQSLKEQHQKEISELNETflsdsEKEKLTLMFEIQGLKEQCDNLQQEKQEAILNYESLREIMEILQ 494
Cdd:COG4913   681 --------DASSDDLAALEEQLEELEAELEEL-----EEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL 747
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 966982775  495 TELGE----------SAGKISQEFESMKQQQASDVHELQQKLRTAFTE 532
Cdd:COG4913   748 RALLEerfaaalgdaVERELRENLEERIDALRARLNRAEEELERAMRA 795
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
462-756 1.09e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.77  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  462 IQGLKEQCDNLQQEKQEAiLNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETV- 540
Cdd:COG1196   195 LGELERQLEPLERQAEKA-ERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELr 273
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  541 NHLQGENEKLLSQQELVPELENTIKNLEEKNGVYLLSLSQRDTMLKELEAKINSLTEEKDDFINKLKNSYEEMDNFHKKC 620
Cdd:COG1196   274 LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL 353
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  621 EREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKL 700
Cdd:COG1196   354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 966982775  701 SSEKKQLSRDLEVFLSQKNDVI-----LKEHITELEKKLQLMVEERDNLNKLLENEQVQKL 756
Cdd:COG1196   434 EEEEEEEEEALEEAAEEEAELEeeeeaLLELLAELLEEAALLEAALAELLEELAEAAARLL 494
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
1080-1328 1.18e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 1.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1080 IETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQ 1159
Cdd:COG3883    18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1160 T----TLMNM-----EIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKntkikqll 1230
Cdd:COG3883    98 SggsvSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA-------- 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1231 vktkKELADSKQAETDHLIlqASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYRQRVTALQEE 1310
Cdd:COG3883   170 ----KAELEAQQAEQEALL--AQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 243
                         250
                  ....*....|....*...
gi 966982775 1311 SRAAKAEQATVTSEFESY 1328
Cdd:COG3883   244 ASAAGAGAAGAAGAAAGS 261
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
978-1229 1.55e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 1.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   978 VAVKAKKELDSSRKETQtvREELESLRSEKDQLSAS-MRDLiqaaesyKNLLLEYEKQSEQLDVEKERANNFEHHVEDLT 1056
Cdd:pfam17380  342 MAMERERELERIRQEER--KRELERIRQEEIAMEISrMREL-------ERLQMERQQKNERVRQELEAARKVKILEEERQ 412
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1057 RQLRNSTLQCEKINSDnedllarietlQSNAKLLEVQILEVQRAKAMvdKELEAEKLQKEQKIKEhaTTVNELEELQVQL 1136
Cdd:pfam17380  413 RKIQQQKVEMEQIRAE-----------QEEARQREVRRLEEERAREM--ERVRLEEQERQQQVER--LRQQEEERKRKKL 477
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1137 QKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQ-EEITSLQSS 1215
Cdd:pfam17380  478 ELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEmEERRRIQEQ 557
                          250
                   ....*....|....
gi 966982775  1216 VQQYEEKNTKIKQL 1229
Cdd:pfam17380  558 MRKATEERSRLEAM 571
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1282-1483 1.62e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.08  E-value: 1.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1282 IHEHLKTSAEQHQRTLSAYRQRVTALQEESRAAKAEqatvtseFESYKVRvHNVLKQQKNKSMSQAETEGAKQEREHLEM 1361
Cdd:COG3206   162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAA-------LEEFRQK-NGLVDLSEEAKLLLQQLSELESQLAEARA 233
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1362 LIDQLKIKLQDSQNNLQMNVSELQTLQSehDTLLERHNKMLQETVSKEAELREKLcsiqsenmmmKSEHtQTVSQLTSQN 1441
Cdd:COG3206   234 ELAEAEARLAALRAQLGSGPDALPELLQ--SPVIQQLRAQLAELEAELAELSARY----------TPNH-PDVIALRAQI 300
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 966982775 1442 EVLRNSFRDQVRHLQEEHRKTVETLQQQLSRVEAQLFQLKNE 1483
Cdd:COG3206   301 AALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEAR 342
PTZ00121 PTZ00121
MAEBL; Provisional
75-901 1.71e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 1.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   75 KALTERLDAILLEKAETEQQCLSLKK--ENIKMKQEVE--DSVTKMEDAHKELEQSHINYVKEIENLKNELMAVRAKYSE 150
Cdd:PTZ00121 1097 FGKAEEAKKTETGKAEEARKAEEAKKkaEDARKAEEARkaEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAK 1176
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  151 DKANLQKELEEAMNKQLELSEQLKFQNNSE--DNVKKLQE--------EIEKIRPAFEEQilylQKQLDATTDEKKETVT 220
Cdd:PTZ00121 1177 KAEAARKAEEVRKAEELRKAEDARKAEAARkaEEERKAEEarkaedakKAEAVKKAEEAK----KDAEEAKKAEEERNNE 1252
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  221 QLQNIIEANSQHYQKNINSLQEEllqlKAIHQEEVKELMCQIEASAKEHETEINKLNELKENLVKQCEASE-KNIQEKYE 299
Cdd:PTZ00121 1253 EIRKFEEARMAHFARRQAAIKAE----EARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEaKKKAEEAK 1328
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  300 CELENLRKATSNANQDNQMCSLLFQENTFVEQVVNEKVKHLEDTLKELESQHSILK---DEVTYMNNLKLKLEMDAQhiK 376
Cdd:PTZ00121 1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKkkaEEKKKADEAKKKAEEDKK--K 1406
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  377 DEFFHEREDLEFKINELLLAKEEQGCVIE-KLKSELAGLNKQFCCTVEQHNKEVQSLKEQHQKEiselnetfLSDSEKEK 455
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKKADEaKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK--------KADEAKKK 1478
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  456 LTLMFEIQGLKEQCDNLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDA 535
Cdd:PTZ00121 1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELK 1558
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  536 LLETVNHLQgENEKLLSQQELVPELENTIKNLEEKNGVYLLSLSQRDTMLKELEAKINSLTEEKDDFINKLKNSYEEMDN 615
Cdd:PTZ00121 1559 KAEEKKKAE-EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQ 1637
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  616 FHKKCEREERLILELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLM--------VQMKVLSEDKEVLS 687
Cdd:PTZ00121 1638 LKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKkeaeeakkAEELKKKEAEEKKK 1717
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  688 AEVKSLYEENNKLSSE--KKQLSRDLEVFLSQKNDVILKEHITELEKKLQLMVEERDNLNKLLENEQVQKlfvktqlygf 765
Cdd:PTZ00121 1718 AEELKKAEEENKIKAEeaKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDE---------- 1787
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  766 lKDMGSEVSEDGEEKDVVNILQAVSESlakinEEKCNLVFQCDKKVFELE-KEIKCLQEESVVQCEELKSLLRDYEQEKV 844
Cdd:PTZ00121 1788 -EDEKRRMEVDKKIKDIFDNFANIIEG-----GKEGNLVINDSKEMEDSAiKEVADSKNMQLEEADAFEKHKFNKNNENG 1861
                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 966982775  845 LLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCNKNEIHNEK 901
Cdd:PTZ00121 1862 EDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDK 1918
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
96-566 1.90e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775    96 LSLKKENIKMKQEVEDSVTKMEDAHKELEQSHINYVKEIENLKNELMAVRAKYSEDKANLQKELEEAMNKQLELSEQLKF 175
Cdd:TIGR04523  203 LSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   176 QNNSEDNVKKLQEEIEKIRPAFEEQILylqKQLDATTDEKKETVTQLQNIIEANsqhyQKNINSLQEELLQLKaihqEEV 255
Cdd:TIGR04523  283 IKELEKQLNQLKSEISDLNNQKEQDWN---KELKSELKNQEKKLEEIQNQISQN----NKIISQLNEQISQLK----KEL 351
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   256 KELMCQIEASAKEHETEINKLNELKENLVKQCEASEKNIQEKYECELENLRKATSNANQDNQMCSLLFQENTFVEQVVN- 334
Cdd:TIGR04523  352 TNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERl 431
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   335 -EKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEqgcvIEKLKSElag 413
Cdd:TIGR04523  432 kETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE----LKKLNEE--- 504
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   414 lNKQFCCTVEQHNKEVQSLKEQHQKEISELN--ETFLSDSEKEKLTLMFEI--QGLKEQCDNLQQEKQEAILNYESLrei 489
Cdd:TIGR04523  505 -KKELEEKVKDLTKKISSLKEKIEKLESEKKekESKISDLEDELNKDDFELkkENLEKEIDEKNKEIEELKQTQKSL--- 580
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   490 mEILQTELGESAGKISQEFESMKQQQASD---VHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQQELVPELENTIKN 566
Cdd:TIGR04523  581 -KKKQEEKQELIDQKEKEKKDLIKEIEEKekkISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRN 659
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
983-1441 1.92e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.29  E-value: 1.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   983 KKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEyeKQSEQLDVEKERANNFEHHVEDLTRQLRns 1062
Cdd:pfam12128  289 NQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLPSWQSELENLEERLK-- 364
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1063 tLQCEKINsdneDLLARIETLQSNAKLLEVQILEVqrakamVDKELEAeklQKEQKIKEHATTVNELEELQVQLQK---- 1138
Cdd:pfam12128  365 -ALTGKHQ----DVTAKYNRRRSKIKEQNNRDIAG------IKDKLAK---IREARDRQLAVAEDDLQALESELREqlea 430
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1139 -------EKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITS 1211
Cdd:pfam12128  431 gklefneEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQ 510
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1212 LQSSVQQYEEKNTKIKQ--------LLVKTKKELADSKQAE----TDHLILQASLKGELEASQ--QQVEVYKIQL---AE 1274
Cdd:pfam12128  511 ASRRLEERQSALDELELqlfpqagtLLHFLRKEAPDWEQSIgkviSPELLHRTDLDPEVWDGSvgGELNLYGVKLdlkRI 590
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1275 ITSEKHKIHEHLKTSAEQHQRTLSAYRQRVTALQEESRAAKAE----QATVTSEFESYK-----VRVHNVLKQQKNKSMS 1345
Cdd:pfam12128  591 DVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGElekaSREETFARTALKnarldLRRLFDEKQSEKDKKN 670
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1346 QAETEGAKQEREHLEMLIDQLKIKLQDSQnnlqmnvselQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMM 1425
Cdd:pfam12128  671 KALAERKDSANERLNSLEAQLKQLDKKHQ----------AWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAA 740
                          490
                   ....*....|....*.
gi 966982775  1426 MKSEHTQTVSQLTSQN 1441
Cdd:pfam12128  741 RRSGAKAELKALETWY 756
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
373-1152 2.08e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.18  E-value: 2.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   373 QHIKDEFFHEREDLEFKINELLLAKEEQGCVIEK----LKSELAGLNKQFCCTVEQHNKEVQS---LKEQHQKEISELNE 445
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQsvidLQTKLQEMQMERDAMADIRRRESQSqedLRNQLQNTVHELEA 156
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   446 tflSDSEKEKLtlmfeiqgLKEQCDNLQQEKQEAILNYESLREIMEILqTELGESAGKISQEFESMKQQQASDVHELQQK 525
Cdd:pfam15921  157 ---AKCLKEDM--------LEDSNTQIEQLRKMMLSHEGVLQEIRSIL-VDFEEASGKKIYEHDSMSTMHFRSLGSAISK 224
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   526 -LRTAFTEKDALLETVNHLQGENEKLLSqqelvpelentiknlEEKNGVYLLSLSQRD---TMLKELEAKINSLTEEKDD 601
Cdd:pfam15921  225 iLRELDTEISYLKGRIFPVEDQLEALKS---------------ESQNKIELLLQQHQDrieQLISEHEVEITGLTEKASS 289
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   602 FINKLKNSYEEMDNFHKKCEREERLILelgkkveqttQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVqmkvlse 681
Cdd:pfam15921  290 ARSQANSIQSQLEIIQEQARNQNSMYM----------RQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLV------- 352
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   682 dkeVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSqknDVILKEHITELEKKLQLMVEERDNLNKL----LENEQVQKLF 757
Cdd:pfam15921  353 ---LANSELTEARTERDQFSQESGNLDDQLQKLLA---DLHKREKELSLEKEQNKRLWDRDTGNSItidhLRRELDDRNM 426
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   758 VKTQLYGFLKDMGSEVSedGEEKDVVNILQAVSESLAKINEEKCNL--VFQCDKKVFELEKEIKCLQEESVVQCEELKSL 835
Cdd:pfam15921  427 EVQRLEALLKAMKSECQ--GQMERQMAAIQGKNESLEKVSSLTAQLesTKEMLRKVVEELTAKKMTLESSERTVSDLTAS 504
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   836 LRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTR---LENQNLLIQVEEVSQTCNKNEIHNEKEKCSIKEHENL 912
Cdd:pfam15921  505 LQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRnvqTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRT 584
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   913 KPLLE----QKESELRDTRAELILLKDSLAKSPSVQNDLLSSVkeleekleNLEKEGKEKEEKINKIKLVAVK-AKKELD 987
Cdd:pfam15921  585 AGAMQvekaQLEKEINDRRLELQEFKILKDKKDAKIRELEARV--------SDLELEKVKLVNAGSERLRAVKdIKQERD 656
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   988 SSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNlLLEYEKQSEQLDVEKERaNNFEHHVEDLTRQLRNSTLQCE 1067
Cdd:pfam15921  657 QLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN-KLKMQLKSAQSELEQTR-NTLKSMEGSDGHAMKVAMGMQK 734
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1068 KINSDNedllARIETLQSNAKLLEVQILEVQRAKAMvdkeLEAEKLQKEQKIKEHATTVNELE-ELQVqLQKEKKQLQKT 1146
Cdd:pfam15921  735 QITAKR----GQIDALQSKIQFLEEAMTNANKEKHF----LKEEKNKLSQELSTVATEKNKMAgELEV-LRSQERRLKEK 805

                   ....*.
gi 966982775  1147 MQELEL 1152
Cdd:pfam15921  806 VANMEV 811
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
322-672 2.28e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.75  E-value: 2.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   322 LFQENTFVEQVVNEKVKHLEDT---LKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEffheREDLEFKINELLLAKE 398
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDAsrkIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE----IENVKSELKELEARIE 768
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   399 EQGCVIEKLKSELAGLNKQFCCT-VEQHNKEVQSLKEQHQKEISELNET--FLSDSEKEKLTLMFEIQGLKEQCDNLQQE 475
Cdd:TIGR02169  769 ELEEDLHKLEEALNDLEARLSHSrIPEIQAELSKLEEEVSRIEARLREIeqKLNRLTLEKEYLEKEIQELQEQRIDLKEQ 848
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   476 KQEAILNYESLREIMEILQTELGESAGKIsQEFESMKQQQASDVHELQQKLRTAFTEKDAL---LETVNHLQGE-NEKLL 551
Cdd:TIGR02169  849 IKSIEKEIENLNGKKEELEEELEELEAAL-RDLESRLGDLKKERDELEAQLRELERKIEELeaqIEKKRKRLSElKAKLE 927
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   552 SQQELVPELENTIKNLEEKNGVyLLSLSQRDTMLKELEAKINSLTEEKDDFINKLKNS---YEEMDNFHKKCEREERLIL 628
Cdd:TIGR02169  928 ALEEELSEIEDPKGEDEEIPEE-ELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVlkrLDELKEKRAKLEEERKAIL 1006
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966982775   629 ELGKKVEQT---------TQYNS----------------ELEQKVNELTGGLEETLKEKDQNDQKLEKL 672
Cdd:TIGR02169 1007 ERIEEYEKKkrevfmeafEAINEnfneifaelsggtgelILENPDDPFAGGLELSAKPKGKPVQRLEAM 1075
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
1069-1207 2.79e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.51  E-value: 2.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1069 INSDNEDLLARIETLQSNAKLLEVQILEVQRakamvdKELEAEKLQKEQKikehattvNELEELQVQLQKEKKQLQKTMQ 1148
Cdd:PRK00409  511 IGEDKEKLNELIASLEELERELEQKAEEAEA------LLKEAEKLKEELE--------EKKEKLQEEEDKLLEEAEKEAQ 576
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966982775 1149 E-LELVKKDAQQT--TLMNMEIADYERL-MKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQE 1207
Cdd:PRK00409  577 QaIKEAKKEADEIikELRQLQKGGYASVkAHELIEARKRLNKANEKKEKKKKKQKEKQEELKV 639
PRK12704 PRK12704
phosphodiesterase; Provisional
1088-1222 3.21e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 3.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1088 KLLEVQILEVQ-RAKAMVD---KELEAEKLQKEQKIKEhattvnELEELQVQLQKEKKQLQKTMQELElvkkdaqqttlm 1163
Cdd:PRK12704   27 KIAEAKIKEAEeEAKRILEeakKEAEAIKKEALLEAKE------EIHKLRNEFEKELRERRNELQKLE------------ 88
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 966982775 1164 nmeiadyERLMKELNQkLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEK 1222
Cdd:PRK12704   89 -------KRLLQKEEN-LDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE 139
YydB COG5293
Uncharacterized conserved protein YydD, contains DUF2326 domain [Function unknown];
472-740 3.32e-03

Uncharacterized conserved protein YydD, contains DUF2326 domain [Function unknown];


Pssm-ID: 444096 [Multi-domain]  Cd Length: 572  Bit Score: 42.24  E-value: 3.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  472 LQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEK--DALLETVNHLQGENEK 549
Cdd:COG5293   182 LAAEKYELKEEIKELKKLRKALKDELIGSVVKSISELRAEILELEEEIEKLEKDLEKFDVAEnyEELEKELDELKREINE 261
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  550 LLSQQElvpELENTIKNLEEkngvyllSL-SQRDTMLKELEAKINSLTEEKDDFINKlknSYEEMDNFHKKCEREERliL 628
Cdd:COG5293   262 LRNERY---SLERRLKKIER-------SLeEEIDIDPDELEKLYEEAGVFFPDQVKK---RFEEVEAFHKSIVENRR--E 326
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  629 ELGKKVEQTTQYNSELEQKVNELTGGLEETLKEKDQND--QKLEKLMVQMKVLSEDKEVLSA---EVKSLYEENNKLSSE 703
Cdd:COG5293   327 YLEEEIAELEAELEELEAELAELGKERAELLSLLDSKGalDKYKELQEELAELEAELEELESrleKLQELEDEIRELKEE 406
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 966982775  704 KKQLSRDLEVFLSQKndvilKEHITELEKKLQLMVEE 740
Cdd:COG5293   407 RAELKEEIESDIEER-----KELLDEINKLFSEIVEE 438
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1092-1374 3.89e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 3.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1092 VQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLmnmEIADYE 1171
Cdd:COG4372    24 ILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQA---ELAQAQ 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1172 RLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQ 1251
Cdd:COG4372   101 EELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAE 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1252 ASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTSEFESYKVR 1331
Cdd:COG4372   181 AEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEI 260
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 966982775 1332 VHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQ 1374
Cdd:COG4372   261 EELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLN 303
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
985-1242 4.03e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.12  E-value: 4.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   985 ELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVekeranNFEHHVEDLTRQLRNS-- 1062
Cdd:pfam10174  469 ELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEI------AVEQKKEECSKLENQLkk 542
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1063 TLQCEKINSDNEDLLARIETLQSNAKLLEVqilEVQRAKAMVD------KELEAEKLQKEQKIkehattvNELEELQVQL 1136
Cdd:pfam10174  543 AHNAEEAVRTNPEINDRIRLLEQEVARYKE---ESGKAQAEVErllgilREVENEKNDKDKKI-------AELESLTLRQ 612
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1137 QKE--KKQLQKTMQELELVKKDAQQttlmnmeiaDYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEITSLQS 1214
Cdd:pfam10174  613 MKEqnKKVANIKHGQQEMKKKGAQL---------LEEARRREDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQ 683
                          250       260
                   ....*....|....*....|....*...
gi 966982775  1215 SVQQYEEKNTKIKQLLVKTKKELADSKQ 1242
Cdd:pfam10174  684 SLAEKDGHLTNLRAERRKQLEEILEMKQ 711
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
404-692 4.30e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.85  E-value: 4.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  404 IEKLKSELAGLNKQfccTVEQHNKEVQSLKEQHQKEISELNETfLSDSEKEKLTLMFEIQGLKEQCDNLQQEKQEAILNY 483
Cdd:COG1196   222 LKELEAELLLLKLR---ELEAELEELEAELEELEAELEELEAE-LAELEAELEELRLELEELELELEEAQAEEYELLAEL 297
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  484 ESLREIMEILQ---TELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQQELVPEL 560
Cdd:COG1196   298 ARLEQDIARLEerrRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  561 ENTIKNLEEKNGVYLLSLSQRDTMLKELEAKINSLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEQTTQY 640
Cdd:COG1196   378 EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 966982775  641 NSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKS 692
Cdd:COG1196   458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
1102-1352 4.78e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 4.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1102 AMVDKELEAEKLQKEQKIKEHATTVNELEELQvqlqkekKQLQKTMQELElvkkdaqqttlmnmeiadyerlmkELNQKL 1181
Cdd:COG3883    12 AFADPQIQAKQKELSELQAELEAAQAELDALQ-------AELEELNEEYN------------------------ELQAEL 60
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1182 SNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLvkTKKELAD--------SKQAETDHLILQas 1253
Cdd:COG3883    61 EALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYLDVLL--GSESFSDfldrlsalSKIADADADLLE-- 136
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1254 lkgELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTSEFESYKVRVH 1333
Cdd:COG3883   137 ---ELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAA 213
                         250
                  ....*....|....*....
gi 966982775 1334 NVLKQQKNKSMSQAETEGA 1352
Cdd:COG3883   214 AAAAAAAAAAAAAAAAAAA 232
46 PHA02562
endonuclease subunit; Provisional
522-770 4.78e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.54  E-value: 4.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  522 LQQKLRTAFTEKDALLETVNHLQgenEKLLSQQELVPELENTIK-NLEEKNGVYllslsqrDTMLKE---LEAKINSLTE 597
Cdd:PHA02562  172 NKDKIRELNQQIQTLDMKIDHIQ---QQIKTYNKNIEEQRKKNGeNIARKQNKY-------DELVEEaktIKAEIEELTD 241
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  598 EKDDF----------INKLKNSYEEMDNFHKKCEREERLILELG------KKVEQTTQYNSELEQKVNELTGGLEETLKE 661
Cdd:PHA02562  242 ELLNLvmdiedpsaaLNKLNTAAAKIKSKIEQFQKVIKMYEKGGvcptctQQISEGPDRITKIKDKLKELQHSLEKLDTA 321
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  662 KDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRdlevflSQKNDVILKEHITELEKKLQLMVEER 741
Cdd:PHA02562  322 IDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEE------LQAEFVDNAEELAKLQDELDKIVKTK 395
                         250       260
                  ....*....|....*....|....*....
gi 966982775  742 DNLnklleneqVQKLFVKTQLYGFLKDMG 770
Cdd:PHA02562  396 SEL--------VKEKYHRGIVTDLLKDSG 416
PRK01156 PRK01156
chromosome segregation protein; Provisional
533-1099 4.85e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.81  E-value: 4.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  533 KDALLETVNHLQGENEKLLSQQ-ELVPELENTIKNLEEKNGVYLLslsqRDTMLKELEAKINSLteekDDFINKLKNSYE 611
Cdd:PRK01156  126 KDVFLNSIFVGQGEMDSLISGDpAQRKKILDEILEINSLERNYDK----LKDVIDMLRAEISNI----DYLEEKLKSSNL 197
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  612 EMDNFHKKCEREERLILELGKKVEQ-TTQYNSELEQKVNeltggLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEV 690
Cdd:PRK01156  198 ELENIKKQIADDEKSHSITLKEIERlSIEYNNAMDDYNN-----LKSALNELSSLEDMKNRYESEIKTAESDLSMELEKN 272
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  691 ---KSLYEENNKLSSEKKQLSRD-LEVFLSQKNDVI-LKEHITELEKKLQlmvEERDNLNKLLENEQVQKLFVKTQL-YG 764
Cdd:PRK01156  273 nyyKELEERHMKIINDPVYKNRNyINDYFKYKNDIEnKKQILSNIDAEIN---KYHAIIKKLSVLQKDYNDYIKKKSrYD 349
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  765 FLKDMGSEVSEDgeEKDVVNILQAVSESLAKINEEKCNLVFQCD------KKVFELEKEIKCLQEESVVQCEELKSLLRD 838
Cdd:PRK01156  350 DLNNQILELEGY--EMDYNSYLKSIESLKKKIEEYSKNIERMSAfiseilKIQEIDPDAIKKELNEINVKLQDISSKVSS 427
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  839 YEQEKVLLRKELEEIQSEKEALQ---------SDLLEMKN-------ANEKTRLENQnlLIQVEEVSQTCNKNEIHNEK- 901
Cdd:PRK01156  428 LNQRIRALRENLDELSRNMEMLNgqsvcpvcgTTLGEEKSnhiinhyNEKKSRLEEK--IREIEIEVKDIDEKIVDLKKr 505
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  902 ----EKCSIKEHENLKPLLEQKESELRDTRAELILLKDSLAKSPSVQNDLLSSVKELEEKLENLEKEGKEKEEKINKIKL 977
Cdd:PRK01156  506 keylESEEINKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDIETN 585
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  978 VAVK--AKKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLE--------------YEKQSEQLDVE 1041
Cdd:PRK01156  586 RSRSneIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQEnkilieklrgkidnYKKQIAEIDSI 665
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 966982775 1042 KERANNFEHHVEDLTRQLRNSTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQR 1099
Cdd:PRK01156  666 IPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINE 723
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
98-292 4.86e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 4.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   98 LKKENIKMKQEVEDSVTKMEDAHKELEQSHINYVKEIENLKNELmavrAKYSEDKANLQKELEEAM---NKQLELSEQLK 174
Cdd:PRK05771   66 LPKLNPLREEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEI----SELENEIKELEQEIERLEpwgNFDLDLSLLLG 141
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  175 FQNN-------SEDNVKKLQEEIEKIRPAFEEQ--------ILYLQKQLDATTDEKKEtvTQLQNIIEANSQHYQKNINS 239
Cdd:PRK05771  142 FKYVsvfvgtvPEDKLEELKLESDVENVEYISTdkgyvyvvVVVLKELSDEVEEELKK--LGFERLELEEEGTPSELIRE 219
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 966982775  240 LQEELLQLKAIhQEEVKElmcQIEASAKEHETEINKLNELKENLVKQCEASEK 292
Cdd:PRK05771  220 IKEELEEIEKE-RESLLE---ELKELAKKYLEELLALYEYLEIELERAEALSK 268
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1188-1422 4.93e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 4.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1188 IEDLEQEIKIQKQKQETLqEEITSLQSSVQQYEEKNTKIKQLlvktkKELADSKQAETDHLILQAslkgELEASQQQVEV 1267
Cdd:COG4913   237 LERAHEALEDAREQIELL-EPIRELAERYAAARERLAELEYL-----RAALRLWFAQRRLELLEA----ELEELRAELAR 306
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1268 YKIQLAEITSEKHKIHEHLktsAEQHQRTLSAYRQRVTALQEESRAAKAEQATVtsefesykvrvhnvlkqqknksmsqa 1347
Cdd:COG4913   307 LEAELERLEARLDALREEL---DELEAQIRGNGGDRLEQLEREIERLERELEER-------------------------- 357
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966982775 1348 etegaKQEREHLEMLIDQLKIKLQDSQNNLQMNVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSE 1422
Cdd:COG4913   358 -----ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
984-1186 4.93e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 4.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  984 KELDSSRKETQTVREELESL-------------RSEKDQLSA--SMRDLIQAAESYKNLLLEYEKQSEQLDVEKERANNF 1048
Cdd:COG4913   235 DDLERAHEALEDAREQIELLepirelaeryaaaRERLAELEYlrAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1049 EHHVEDLTRQLRNSTLQCEKINSDnedllaRIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNE 1128
Cdd:COG4913   315 EARLDALREELDELEAQIRGNGGD------RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE 388
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 966982775 1129 LEELQVQLQKEKKQLQKTMQELELVKKDAQQttlmnmeiaDYERLMKELNQKLSNKNN 1186
Cdd:COG4913   389 AAALLEALEEELEALEEALAEAEAALRDLRR---------ELRELEAEIASLERRKSN 437
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
484-741 5.38e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 5.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  484 ESLREIMEILQtELG-----ESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNHLqgeneKLLSQQELVP 558
Cdd:PRK05771   16 SYKDEVLEALH-ELGvvhieDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKV-----SVKSLEELIK 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  559 ELENTIKNLEEKngvyllslsqrdtmLKELEAKINSLTEEKDDfINKLKNSYEEMDNFH---KKCEREERLILELGK-KV 634
Cdd:PRK05771   90 DVEEELEKIEKE--------------IKELEEEISELENEIKE-LEQEIERLEPWGNFDldlSLLLGFKYVSVFVGTvPE 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  635 EQTTQYNSELEQKVNELTGGLEE-------TLKEKDQNDQK-LEKLMVQMKVLSEDKeVLSAEVKSLYEENNKLSSEKKQ 706
Cdd:PRK05771  155 DKLEELKLESDVENVEYISTDKGyvyvvvvVLKELSDEVEEeLKKLGFERLELEEEG-TPSELIREIKEELEEIEKERES 233
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 966982775  707 LSRDLEVFLSQKNDVIL--KEHITELEKKLQLMVEER 741
Cdd:PRK05771  234 LLEELKELAKKYLEELLalYEYLEIELERAEALSKFL 270
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
99-923 5.40e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.50  E-value: 5.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775    99 KKENIKMKQEVEDSVTKMEDAHKELEQSHINYVKEIENLKNELMAVRAKYSEDKANLQKELEEAMNKQLELSEQLKFQNN 178
Cdd:pfam02463  171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQ 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   179 SEDNVKKLQEEIEKIRPAFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEEL------LQLKAIHQ 252
Cdd:pfam02463  251 EEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLkesekeKKKAEKEL 330
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   253 EEVKELMCQIEASAKEHETEINKLNELKENLVKQCEASEKNIQEKYECELENLRKATSNANQDNQMCSLLFQENTFVEQV 332
Cdd:pfam02463  331 KKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   333 VNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQgcvieklksela 412
Cdd:pfam02463  411 LELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ------------ 478
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   413 glnkqfccTVEQHNKEVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCDNLQQEKQEAILNYESLREIMEI 492
Cdd:pfam02463  479 --------LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVI 550
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   493 LQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNHLQGENEKLLSQQELVPELENTIKNLEEKNG 572
Cdd:pfam02463  551 VEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILK 630
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   573 VYLLSLSQRDTMLKELEAKINSLTEEKDDFINKLKNSYEEMDNFHKKCEREERLILELGKKVEqttQYNSELEQKVNELT 652
Cdd:pfam02463  631 DTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEE---ILRRQLEIKKKEQR 707
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   653 GGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKNDVILKEHITELEK 732
Cdd:pfam02463  708 EKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK 787
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   733 KLQLMVEERDNLNKLLENEQVQKLFVKTQLYGFLKDMGSEVSEDGEEKDVVNILQAVSESLAKINEEKCNLvfqcdkkVF 812
Cdd:pfam02463  788 VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELER-------LE 860
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   813 ELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTC 892
Cdd:pfam02463  861 EEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEEL 940
                          810       820       830
                   ....*....|....*....|....*....|.
gi 966982775   893 NKNEIHNEKEKCSIKEHENLKPLLEQKESEL 923
Cdd:pfam02463  941 LLEEADEKEKEENNKEEEEERNKRLLLAKEE 971
Filament pfam00038
Intermediate filament protein;
130-308 6.17e-03

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 40.67  E-value: 6.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   130 YVKEIENLKNELMAVRAkyseDKANLQKELEEAmnkqLELSEQLKfqnnsednvKKLQEEIEKiRPAFEEQILYLQKQLD 209
Cdd:pfam00038   52 YEKEIEDLRRQLDTLTV----ERARLQLELDNL----RLAAEDFR---------QKYEDELNL-RTSAENDLVGLRKDLD 113
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   210 ATTDEKketvTQLQNIIEansqhyqkninSLQEELLQLKAIHQEEVKELMCQIEASAKEHETEINK-------LNELKEN 282
Cdd:pfam00038  114 EATLAR----VDLEAKIE-----------SLKEELAFLKKNHEEEVRELQAQVSDTQVNVEMDAARkldltsaLAEIRAQ 178
                          170       180
                   ....*....|....*....|....*.
gi 966982775   283 LVKQCEASEKNIQEKYECELENLRKA 308
Cdd:pfam00038  179 YEEIAAKNREEAEEWYQSKLEELQQA 204
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
67-569 6.19e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.20  E-value: 6.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   67 TEGTDDIIKALTERLDAIL----------------LEKAETEQQCLSLKKENI----KMKQEVEDSVTKMEDAHKELEQS 126
Cdd:PRK03918  188 TENIEELIKEKEKELEEVLreineisselpelreeLEKLEKEVKELEELKEEIeeleKELESLEGSKRKLEEKIRELEER 267
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  127 HINYVKEIENLKN----------------ELMAVRAKYSEDKANLQKELEEAMNKQLELSEQLKFQNNSEDNVKKLQEEI 190
Cdd:PRK03918  268 IEELKKEIEELEEkvkelkelkekaeeyiKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKL 347
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  191 EKIRPAFEEQILYLQKqldatTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHE 270
Cdd:PRK03918  348 KELEKRLEELEERHEL-----YEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK 422
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  271 TEINKLNELKENLVK-------QCEASEKNIQEKYECELENLRKATSNANQDNqmcSLLFQENTFVEQVVNE-----KVK 338
Cdd:PRK03918  423 ELKKAIEELKKAKGKcpvcgreLTEEHRKELLEEYTAELKRIEKELKEIEEKE---RKLRKELRELEKVLKKeseliKLK 499
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  339 HLEDTLKELESQ-HSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEfKINELLLAKEEQGCVIEKLKSELAGLNKQ 417
Cdd:PRK03918  500 ELAEQLKELEEKlKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLDELEEELAELLKE 578
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  418 F----CCTVEQHNKEVQSLKEQHQKEISelnetfLSDSEKEKLTLMFEIQGLKEQCDNLQQEKQEAILNYESLREIMEIL 493
Cdd:PRK03918  579 LeelgFESVEELEERLKELEPFYNEYLE------LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEEL 652
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966982775  494 QTELG-ESAGKISQEFESMKQQQASdvheLQQKLRTAFTEKDALLETVNHLQGENEKLLSQQELVPELENTIKNLEE 569
Cdd:PRK03918  653 EKKYSeEEYEELREEYLELSRELAG----LRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE 725
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1093-1209 6.52e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.38  E-value: 6.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1093 QILEVQRAKAMVDKELEAEKL---------QKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTtlm 1163
Cdd:COG2433   380 EALEELIEKELPEEEPEAEREkeheereltEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE--- 456
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 966982775 1164 nmeiadyERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQEEI 1209
Cdd:COG2433   457 -------ERREIRKDREISRLDREIERLERELEEERERIEELKRKL 495
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
984-1321 7.12e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 40.99  E-value: 7.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  984 KELDSSRKETQTVREELESLrseKDQLSASMRDLIQAAESYKNLLLEYEKQseqlDVEKERANNFEhhVEDLTRQLRNST 1063
Cdd:PLN03229  422 KKREAVKTPVRELEGEVEKL---KEQILKAKESSSKPSELALNEMIEKLKK----EIDLEYTEAVI--AMGLQERLENLR 492
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1064 LQCEKINSDNE----DLLARIETLQSNAKL------------LEVQIL-EVQRAKAMVDKELEAEKLQKE--QKIKEhAT 1124
Cdd:PLN03229  493 EEFSKANSQDQlmhpVLMEKIEKLKDEFNKrlsrapnylslkYKLDMLnEFSRAKALSEKKSKAEKLKAEinKKFKE-VM 571
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1125 TVNELEElQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEI-ADYERLMKELNQKLSNKNNKIEDLEQEIKIQ--KQK 1201
Cdd:PLN03229  572 DRPEIKE-KMEALKAEVASSGASSGDELDDDLKEKVEKMKKEIeLELAGVLKSMGLEVIGVTKKNKDTAEQTPPPnlQEK 650
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1202 QETLQEEITSLQSSVQQYEEKNTKIKQLlvktKKELADSKQAEtdhlilQASLKGELEASQQQVEvYKIQLAEITSEKHK 1281
Cdd:PLN03229  651 IESLNEEINKKIERVIRSSDLKSKIELL----KLEVAKASKTP------DVTEKEKIEALEQQIK-QKIAEALNSSELKE 719
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 966982775 1282 IHEHLKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATV 1321
Cdd:PLN03229  720 KFEELEAELAAARETAAESNGSLKNDDDKEEDSKEDGSRV 759
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
132-317 7.23e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 7.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  132 KEIENLKNELMAVRAKYsedkANLQKELEEAMNKQLELSEQLKfqnNSEDNVKKLQEEIEKIrpafEEQILYLQKQLD-- 209
Cdd:COG3883    23 KELSELQAELEAAQAEL----DALQAELEELNEEYNELQAELE---ALQAEIDKLQAEIAEA----EAEIEERREELGer 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  210 -ATTDEKKETVTQLQNIIEANS--------------QHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHETEIN 274
Cdd:COG3883    92 aRALYRSGGSVSYLDVLLGSESfsdfldrlsalskiADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKA 171
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 966982775  275 KLNELK---ENLVKQCEASEKNIQEKYECELENLRKATSNANQDNQ 317
Cdd:COG3883   172 ELEAQQaeqEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217
PRK11281 PRK11281
mechanosensitive channel MscK;
75-355 7.31e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.05  E-value: 7.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   75 KALTERLDAILLEKAETEQQclslKKENIKMKQEVEDSVTKMEDAHKELeqshinyvkeiENLKNELMAVRAKYSEDK-- 152
Cdd:PRK11281   59 KLVQQDLEQTLALLDKIDRQ----KEETEQLKQQLAQAPAKLRQAQAEL-----------EALKDDNDEETRETLSTLsl 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  153 ANLQKELEEAMNKQLELSEQLKFQNNSEDNVKKLQEEIEKIRPAFEEQILYLQKQLDATTDEKKETVTQLQNIIEAnSQH 232
Cdd:PRK11281  124 RQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQA-EQA 202
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  233 YQKNINSLQEELL----QLKAIHQEEVKELMCQIEASAKEHE---TEIN-KLNELKENLVKQCEASEKN--IQE----KY 298
Cdd:PRK11281  203 LLNAQNDLQRKSLegntQLQDLLQKQRDYLTARIQRLEHQLQllqEAINsKRLTLSEKTVQEAQSQDEAarIQAnplvAQ 282
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966982775  299 ECEL-----ENLRKATSNANQdnqmcslLFQENTFVEQVVNekvkHLEDTLKELESQHSILK 355
Cdd:PRK11281  283 ELEInlqlsQRLLKATEKLNT-------LTQQNLRVKNWLD----RLTQSERNIKEQISVLK 333
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1007-1218 7.33e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 7.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1007 KDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDV------EKERANNFEHHVEDLTRQLRNSTLQCEKINSDNEDLLARI 1080
Cdd:COG3206   163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAaleefrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARL 242
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1081 ETLQSNAKLLEVQILEVQRAKAMVD-----KELEAEKLQKEQKIKEHATTV----NELEELQVQLQKEKKQLQKTMqELE 1151
Cdd:COG3206   243 AALRAQLGSGPDALPELLQSPVIQQlraqlAELEAELAELSARYTPNHPDVialrAQIAALRAQLQQEAQRILASL-EAE 321
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966982775 1152 LVKKDAQQTTLMNmEIADYERLMKELNQKLSnknnKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQ 1218
Cdd:COG3206   322 LEALQAREASLQA-QLAQLEARLAELPELEA----ELRRLEREVEVARELYESLLQRLEEARLAEAL 383
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
980-1441 8.03e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.19  E-value: 8.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775   980 VKAKKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLDVEkerannfehHVEDLTRQL 1059
Cdd:TIGR00606  322 VDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFE---------RGPFSERQI 392
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1060 RNS-TLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQV---Q 1135
Cdd:TIGR00606  393 KNFhTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGssdR 472
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1136 LQKEKKQLQKTMQELELVKKDAQQTTLMNMEI------ADYERLMKELNQKLSNKNNKIEDLEQEIKIQKQKQETLQE-- 1207
Cdd:TIGR00606  473 ILELDQELRKAERELSKAEKNSLTETLKKEVKslqnekADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQir 552
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1208 EITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLilqASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHL- 1286
Cdd:TIGR00606  553 KIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRL---AKLNKELASLEQNKNHINNELESKEEQLSSYEDKLf 629
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  1287 -KTSAEQHQRTLSAYRQRVtalqEESRAAKAEQATVTSEFESYKVRVHNvlkqqKNKSMSQAETEGAKQEREhLEMLIDQ 1365
Cdd:TIGR00606  630 dVCGSQDEESDLERLKEEI----EKSSKQRAMLAGATAVYSQFITQLTD-----ENQSCCPVCQRVFQTEAE-LQEFISD 699
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 966982775  1366 LKIKLQDSQNNLQMNVSELQTLQSEHDTLL---ERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQN 1441
Cdd:TIGR00606  700 LQSKLRLAPDKLKSTESELKKKEKRRDEMLglaPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIM 778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
960-1187 8.22e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 8.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  960 NLEKEGKekeekinkiklvavKAKKELDSSRKETQTVREELESLRSEKDQLSASMRDLIQAAESYKNLLLEYEKQSEQLD 1039
Cdd:COG4942    31 QLQQEIA--------------ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1040 VE-KERANNFEHHVEDLTRQLRNSTLQCEKINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAmvdkELEAEKLQKEQK 1118
Cdd:COG4942    97 AElEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA----ELAALRAELEAE 172
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1119 IKEHATTVNELEELQVQLQKEKKQLQKTMQELEL-VKKDAQQTTLMNMEIADYERLMKELNQKLSNKNNK 1187
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKeLAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
213-460 8.30e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 40.68  E-value: 8.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  213 DEKKETVTQLQN-----IIEANSQ-------HYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHETEINKLNELK 280
Cdd:PRK05771   16 SYKDEVLEALHElgvvhIEDLKEElsnerlrKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEEL 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  281 ENLVKQCEASEKNIQE------KYECELENLRKaTSNANQDNQmcslLFQENTFVEQVVNEKVKHLEDTLKELESQH--- 351
Cdd:PRK05771   96 EKIEKEIKELEEEISEleneikELEQEIERLEP-WGNFDLDLS----LLLGFKYVSVFVGTVPEDKLEELKLESDVEnve 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775  352 --SILKDEVTYM-NNLKLKlemdaqhiKDEFFHEREDLEFKINELL---LAKEeqgcVIEKLKSELAGLNKQfcctVEQH 425
Cdd:PRK05771  171 yiSTDKGYVYVVvVVLKEL--------SDEVEEELKKLGFERLELEeegTPSE----LIREIKEELEEIEKE----RESL 234
                         250       260       270
                  ....*....|....*....|....*....|....*
gi 966982775  426 NKEVQSLKEQHQKEISELNETFLSDSEKEKLTLMF 460
Cdd:PRK05771  235 LEELKELAKKYLEELLALYEYLEIELERAEALSKF 269
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1187-1397 9.93e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 9.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1187 KIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQllvktkkeLADSKQAETDHlilqASLKGELEASQQqve 1266
Cdd:COG4913   611 KLAALEAELAELEEELAEAEERLEALEAELDALQERREALQR--------LAEYSWDEIDV----ASAEREIAELEA--- 675
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966982775 1267 vykiQLAEITSEKHKIhEHLKTSAEQHQRTLSAYRQRVTALQEESRAAKAEQATVTSEFESYKVRVhnvlkqqknksmSQ 1346
Cdd:COG4913   676 ----ELERLDASSDDL-AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRL------------EA 738
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 966982775 1347 AETEGAKQEREHLEMLIDQLKIK--LQDSQNNLQMNVSELQTLQSEHDTLLER 1397
Cdd:COG4913   739 AEDLARLELRALLEERFAAALGDavERELRENLEERIDALRARLNRAEEELER 791
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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