INO80 complex subunit B isoform X1 [Macaca mulatta]
Protein Classification
PAPA-1 and zf-HIT domain-containing protein( domain architecture ID 10521558)
PAPA-1 and zf-HIT domain-containing protein
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| zf-HIT_IN80B | cd23021 | zinc finger HIT (zf-HIT) found in INO80 complex subunit B (INO80B) and similar proteins; ... |
329-361 | 2.08e-14 | ||
zinc finger HIT (zf-HIT) found in INO80 complex subunit B (INO80B) and similar proteins; INO80B, also called high mobility group AT-hook 1-like 4 (HMGA1L4), or IES2 homolog, or PAP-1-associated protein 1 (PAPA-1), or zinc finger HIT domain-containing protein 4 (ZNHIT4), is a nucleolar protein that induces growth and cell cycle arrests at the G1 phase of the cell cycle. It is a core component of the chromatin remodeling INO80 complex, which is involved in transcriptional regulation, DNA replication and probably DNA repair. INO80B harbors a zf-HIT domain which is characterized by a fold in "treble-clef" through interleaved CCCC and CCHC ZnF motifs that both bind a zinc atom. The yeast counterpart of INO80B is Ies2p (Ino eighty subunit 2), which doesn't have zf-HIT domain. : Pssm-ID: 467793 Cd Length: 33 Bit Score: 66.53 E-value: 2.08e-14
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| PAPA-1 | pfam04795 | PAPA-1-like conserved region; Family of proteins with a conserved region found in PAPA-1, a ... |
233-309 | 2.74e-09 | ||
PAPA-1-like conserved region; Family of proteins with a conserved region found in PAPA-1, a PAP-1 binding protein. : Pssm-ID: 461431 [Multi-domain] Cd Length: 78 Bit Score: 53.34 E-value: 2.74e-09
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| Name | Accession | Description | Interval | E-value | ||
| zf-HIT_IN80B | cd23021 | zinc finger HIT (zf-HIT) found in INO80 complex subunit B (INO80B) and similar proteins; ... |
329-361 | 2.08e-14 | ||
zinc finger HIT (zf-HIT) found in INO80 complex subunit B (INO80B) and similar proteins; INO80B, also called high mobility group AT-hook 1-like 4 (HMGA1L4), or IES2 homolog, or PAP-1-associated protein 1 (PAPA-1), or zinc finger HIT domain-containing protein 4 (ZNHIT4), is a nucleolar protein that induces growth and cell cycle arrests at the G1 phase of the cell cycle. It is a core component of the chromatin remodeling INO80 complex, which is involved in transcriptional regulation, DNA replication and probably DNA repair. INO80B harbors a zf-HIT domain which is characterized by a fold in "treble-clef" through interleaved CCCC and CCHC ZnF motifs that both bind a zinc atom. The yeast counterpart of INO80B is Ies2p (Ino eighty subunit 2), which doesn't have zf-HIT domain. Pssm-ID: 467793 Cd Length: 33 Bit Score: 66.53 E-value: 2.08e-14
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| PAPA-1 | pfam04795 | PAPA-1-like conserved region; Family of proteins with a conserved region found in PAPA-1, a ... |
233-309 | 2.74e-09 | ||
PAPA-1-like conserved region; Family of proteins with a conserved region found in PAPA-1, a PAP-1 binding protein. Pssm-ID: 461431 [Multi-domain] Cd Length: 78 Bit Score: 53.34 E-value: 2.74e-09
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| zf-HIT | pfam04438 | HIT zinc finger; This presumed zinc finger contains up to 6 cysteine residues that could ... |
327-358 | 1.27e-04 | ||
HIT zinc finger; This presumed zinc finger contains up to 6 cysteine residues that could coordinate zinc. The domain is named after the HIT protein. This domain is also found in the Thyroid receptor interacting protein 3 (TRIP-3) that specifically interact with the ligand binding domain of the thyroid receptor. Pssm-ID: 461310 Cd Length: 30 Bit Score: 38.77 E-value: 1.27e-04
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| Name | Accession | Description | Interval | E-value | ||
| zf-HIT_IN80B | cd23021 | zinc finger HIT (zf-HIT) found in INO80 complex subunit B (INO80B) and similar proteins; ... |
329-361 | 2.08e-14 | ||
zinc finger HIT (zf-HIT) found in INO80 complex subunit B (INO80B) and similar proteins; INO80B, also called high mobility group AT-hook 1-like 4 (HMGA1L4), or IES2 homolog, or PAP-1-associated protein 1 (PAPA-1), or zinc finger HIT domain-containing protein 4 (ZNHIT4), is a nucleolar protein that induces growth and cell cycle arrests at the G1 phase of the cell cycle. It is a core component of the chromatin remodeling INO80 complex, which is involved in transcriptional regulation, DNA replication and probably DNA repair. INO80B harbors a zf-HIT domain which is characterized by a fold in "treble-clef" through interleaved CCCC and CCHC ZnF motifs that both bind a zinc atom. The yeast counterpart of INO80B is Ies2p (Ino eighty subunit 2), which doesn't have zf-HIT domain. Pssm-ID: 467793 Cd Length: 33 Bit Score: 66.53 E-value: 2.08e-14
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| PAPA-1 | pfam04795 | PAPA-1-like conserved region; Family of proteins with a conserved region found in PAPA-1, a ... |
233-309 | 2.74e-09 | ||
PAPA-1-like conserved region; Family of proteins with a conserved region found in PAPA-1, a PAP-1 binding protein. Pssm-ID: 461431 [Multi-domain] Cd Length: 78 Bit Score: 53.34 E-value: 2.74e-09
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| zf-HIT | cd23020 | zinc finger HIT (zf-HIT) domain; The zinc finger HIT (zf-HIT) is a novel zinc-binding domain ... |
330-361 | 3.32e-08 | ||
zinc finger HIT (zf-HIT) domain; The zinc finger HIT (zf-HIT) is a novel zinc-binding domain with about 50 amino acids. It is characterized by a fold in "treble-clef" through interleaved CCCC and CCHC zinc finger motifs that both bind a zinc ion. zf-HIT domain may function as a protein-protein interaction domain. It is mainly found in nuclear proteins involved in gene regulation and chromatin remodeling. The zf-HIT family includes six proteins containing zf-HIT domain present in human and three in yeast proteome, all belonging to multimodular RNA/protein complexes. Pssm-ID: 467792 Cd Length: 31 Bit Score: 49.04 E-value: 3.32e-08
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| zf-HIT | pfam04438 | HIT zinc finger; This presumed zinc finger contains up to 6 cysteine residues that could ... |
327-358 | 1.27e-04 | ||
HIT zinc finger; This presumed zinc finger contains up to 6 cysteine residues that could coordinate zinc. The domain is named after the HIT protein. This domain is also found in the Thyroid receptor interacting protein 3 (TRIP-3) that specifically interact with the ligand binding domain of the thyroid receptor. Pssm-ID: 461310 Cd Length: 30 Bit Score: 38.77 E-value: 1.27e-04
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