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Conserved domains on  [gi|966981458|ref|XP_014967959|]
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N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 isoform X1 [Macaca mulatta]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229488)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Galactosyl_T super family cl21608
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 156-345 2.97e-40

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


The actual alignment was detected with superfamily member pfam01762:

Pssm-ID: 473923 [Multi-domain]  Cd Length: 195  Bit Score: 141.69  E-value: 2.97e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458  156 ARRQAIRESWGQESNTGNQTVVRVFLLGQTPPEDNhpDLSDMLKFESDKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSC 235
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKSLFLVGLSADTDG--KVADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKC 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458  236 PDTEFVFKGDDDVFVNTHHILNYLNSLSKSKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYS-GLYPPYAGGGGFLYSGH 314
Cdd:pfam01762  79 PSAKYIGKIDDDVYFFPDKLLSLLDNGNIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKcSRYPPYASGPFYVLSRD 158

                         170       180       190
                  ....*....|....*....|....*....|.
gi 966981458  315 LALRLYHITDQVHLYPIDDVYTGMCLQKLGL 345
Cdd:pfam01762 159 AAEKLLKASKHRRFLQIEDVYVGILANDLGI 189
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 156-345 2.97e-40

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 141.69  E-value: 2.97e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458  156 ARRQAIRESWGQESNTGNQTVVRVFLLGQTPPEDNhpDLSDMLKFESDKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSC 235
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKSLFLVGLSADTDG--KVADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKC 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458  236 PDTEFVFKGDDDVFVNTHHILNYLNSLSKSKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYS-GLYPPYAGGGGFLYSGH 314
Cdd:pfam01762  79 PSAKYIGKIDDDVYFFPDKLLSLLDNGNIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKcSRYPPYASGPFYVLSRD 158

                         170       180       190
                  ....*....|....*....|....*....|.
gi 966981458  315 LALRLYHITDQVHLYPIDDVYTGMCLQKLGL 345
Cdd:pfam01762 159 AAEKLLKASKHRRFLQIEDVYVGILANDLGI 189
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 139-391 2.49e-14

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 74.45  E-value: 2.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458 139 AKKPF-LLLAIKSLTPHFARRQAIRESWGQESNTGNQTVVRVFLLGQtppeDNHPDLSDMLKFESDKHQDILMWNYRDtF 217
Cdd:PLN03133 381 PKKPLdLFIGVFSTANNFKRRMAVRRTWMQYDAVRSGAVAVRFFVGL----HKNQMVNEELWNEARTYGDIQLMPFVD-Y 455

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458 218 FNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVFVNTHHILNYLNSLSKSKAkdLFIGDVIHNAGPHRDKKLKYYI-PEVVY 296
Cdd:PLN03133 456 YSLITWKTLAICIFGTEVVSAKYVMKTDDDAFVRVDEVLASLKRTNVSHG--LLYGLINSDSQPHRNPDSKWYIsPEEWP 533

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458 297 SGLYPPYAGGGGFLYSGHLALRLY--HITDQVHLYPIDDVYTGMCLQKLglvpEKHKGFRTFDIEEKNKNNICS--YVdl 372
Cdd:PLN03133 534 EETYPPWAHGPGYVVSRDIAKEVYkrHKEGRLKMFKLEDVAMGIWIAEM----KKEGLEVKYENDGRIYNEGCKdgYV-- 607

                        250
                 ....*....|....*....
gi 966981458 373 mLVHSRKPQEMIDIWSQLQ 391
Cdd:PLN03133 608 -VAHYQSPREMLCLWQKLQ 625
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 156-345 2.97e-40

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 141.69  E-value: 2.97e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458  156 ARRQAIRESWGQESNTGNQTVVRVFLLGQTPPEDNhpDLSDMLKFESDKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSC 235
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKSLFLVGLSADTDG--KVADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKC 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458  236 PDTEFVFKGDDDVFVNTHHILNYLNSLSKSKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYS-GLYPPYAGGGGFLYSGH 314
Cdd:pfam01762  79 PSAKYIGKIDDDVYFFPDKLLSLLDNGNIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKcSRYPPYASGPFYVLSRD 158

                         170       180       190
                  ....*....|....*....|....*....|.
gi 966981458  315 LALRLYHITDQVHLYPIDDVYTGMCLQKLGL 345
Cdd:pfam01762 159 AAEKLLKASKHRRFLQIEDVYVGILANDLGI 189
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 139-391 2.49e-14

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 74.45  E-value: 2.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458 139 AKKPF-LLLAIKSLTPHFARRQAIRESWGQESNTGNQTVVRVFLLGQtppeDNHPDLSDMLKFESDKHQDILMWNYRDtF 217
Cdd:PLN03133 381 PKKPLdLFIGVFSTANNFKRRMAVRRTWMQYDAVRSGAVAVRFFVGL----HKNQMVNEELWNEARTYGDIQLMPFVD-Y 455

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458 218 FNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVFVNTHHILNYLNSLSKSKAkdLFIGDVIHNAGPHRDKKLKYYI-PEVVY 296
Cdd:PLN03133 456 YSLITWKTLAICIFGTEVVSAKYVMKTDDDAFVRVDEVLASLKRTNVSHG--LLYGLINSDSQPHRNPDSKWYIsPEEWP 533

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458 297 SGLYPPYAGGGGFLYSGHLALRLY--HITDQVHLYPIDDVYTGMCLQKLglvpEKHKGFRTFDIEEKNKNNICS--YVdl 372
Cdd:PLN03133 534 EETYPPWAHGPGYVVSRDIAKEVYkrHKEGRLKMFKLEDVAMGIWIAEM----KKEGLEVKYENDGRIYNEGCKdgYV-- 607

                        250
                 ....*....|....*....
gi 966981458 373 mLVHSRKPQEMIDIWSQLQ 391
Cdd:PLN03133 608 -VAHYQSPREMLCLWQKLQ 625
PLN03153 PLN03153
hypothetical protein; Provisional
 234-358 6.31e-03

hypothetical protein; Provisional


Pssm-ID: 215605 [Multi-domain]  Cd Length: 537  Bit Score: 38.74  E-value: 6.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966981458 234 SCPDTEFVFKGDDDVFVNTHHILNYLNSLSKSKAkdLFIGdvihnaGPHRDKKLKYYIPevvYSGLYppyaGGGGFLYSG 313
Cdd:PLN03153 207 GLPDVRWFVLGDDDTIFNADNLVAVLSKYDPSEM--VYVG------GPSESHSANSYFS---HNMAF----GGGGIAISY 271

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 966981458 314 HLALRLYHITDQV-----HLYPIDDVYTGmCLQKLGLVPEKHKGFRTFDI 358
Cdd:PLN03153 272 PLAEALSRILDDCldrypKLYGSDDRLHA-CITELGVPLSREPGFHQWDI 320
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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