NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1622855211|ref|XP_014967786|]
View 

tetratricopeptide repeat protein 7A isoform X5 [Macaca mulatta]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TTC7_N super family cl44857
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 9-403 3.85e-150

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


The actual alignment was detected with superfamily member pfam19440:

Pssm-ID: 466084  Cd Length: 386  Bit Score: 447.30  E-value: 3.85e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211   9 SHLKVESELERCRAEGHWDRMPELVRQLQSLSMPggggnrrgipsaaftfpdTDDFGKLLLAEALLEQCLKENHAKIKDS 88
Cdd:pfam19440   8 SGYRLETEIERCRSECQWDKVPELVEQLKAKRIA------------------NDDMANLLLGEGKLEQYLKENPPILENS 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211  89 IpllEKNEPKMSEAKNYLSSILNHGRLTPQYMCEAMLILGKLHYVEGSYRDAISMYARAGIDDVSMENKPLYQMRLLSEA 168
Cdd:pfam19440  70 T---EKNQPKLSEAKKHLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEA 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 169 FVIKGLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLKGCHPV-DYELTYFLEAALQSA 247
Cdd:pfam19440 147 YAIKGLCLEKQAVSSSSRVRLAEREEEMITCYEKAGDIALLYLQELERINSNTQNRSPKPGPPSqEQELGFFLETALQRA 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 248 YVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEE-NSFATQA--- 323
Cdd:pfam19440 227 YVLYFKKGNLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPlKGTNTKNytp 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 324 LRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRAVSLQNAAAIYDLLSITLGRRGQYVMLSECL 403
Cdd:pfam19440 307 SRKPRVYSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 734-871 1.06e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 94.29  E-value: 1.06e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 734 LEQIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLML 813
Cdd:COG3914    77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622855211 814 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 871
Cdd:COG3914   157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNA 214
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 367-628 1.00e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.27  E-value: 1.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 367 EQEEDRAVS-LQNAAAI---YDLLSITLG----RRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLR 438
Cdd:COG2956    21 NGQPDKAIDlLEEALELdpeTVEAHLALGnlyrRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 439 ECVKLRPSDPTVPLMAAKVCIGSLHWlEEAERFAMMVISLGEEAGEFlpkgYLALGLTYslqatdatLKSKQDElhrKAL 518
Cdd:COG2956   101 KLLELDPDDAEALRLLAEIYEQEGDW-EKAIEVLERLLKLGPENAHA----YCELAELY--------LEQGDYD---EAI 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 519 QTLERAQQLAPGDPQVILYVSLQLALVRQISSAMEQLQEALKVCKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPE 598
Cdd:COG2956   165 EALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244

                         250       260       270
                  ....*....|....*....|....*....|
gi 1622855211 599 NfNLMFTKVKLEQALKGPEEALVTCRQMLR 628
Cdd:COG2956   245 D-DLLLALADLLERKEGLEAALALLERQLR 273
 
Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 9-403 3.85e-150

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 447.30  E-value: 3.85e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211   9 SHLKVESELERCRAEGHWDRMPELVRQLQSLSMPggggnrrgipsaaftfpdTDDFGKLLLAEALLEQCLKENHAKIKDS 88
Cdd:pfam19440   8 SGYRLETEIERCRSECQWDKVPELVEQLKAKRIA------------------NDDMANLLLGEGKLEQYLKENPPILENS 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211  89 IpllEKNEPKMSEAKNYLSSILNHGRLTPQYMCEAMLILGKLHYVEGSYRDAISMYARAGIDDVSMENKPLYQMRLLSEA 168
Cdd:pfam19440  70 T---EKNQPKLSEAKKHLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEA 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 169 FVIKGLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLKGCHPV-DYELTYFLEAALQSA 247
Cdd:pfam19440 147 YAIKGLCLEKQAVSSSSRVRLAEREEEMITCYEKAGDIALLYLQELERINSNTQNRSPKPGPPSqEQELGFFLETALQRA 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 248 YVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEE-NSFATQA--- 323
Cdd:pfam19440 227 YVLYFKKGNLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPlKGTNTKNytp 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 324 LRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRAVSLQNAAAIYDLLSITLGRRGQYVMLSECL 403
Cdd:pfam19440 307 SRKPRVYSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 734-871 1.06e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 94.29  E-value: 1.06e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 734 LEQIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLML 813
Cdd:COG3914    77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622855211 814 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 871
Cdd:COG3914   157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNA 214
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 367-628 1.00e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.27  E-value: 1.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 367 EQEEDRAVS-LQNAAAI---YDLLSITLG----RRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLR 438
Cdd:COG2956    21 NGQPDKAIDlLEEALELdpeTVEAHLALGnlyrRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 439 ECVKLRPSDPTVPLMAAKVCIGSLHWlEEAERFAMMVISLGEEAGEFlpkgYLALGLTYslqatdatLKSKQDElhrKAL 518
Cdd:COG2956   101 KLLELDPDDAEALRLLAEIYEQEGDW-EKAIEVLERLLKLGPENAHA----YCELAELY--------LEQGDYD---EAI 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 519 QTLERAQQLAPGDPQVILYVSLQLALVRQISSAMEQLQEALKVCKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPE 598
Cdd:COG2956   165 EALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244

                         250       260       270
                  ....*....|....*....|....*....|
gi 1622855211 599 NfNLMFTKVKLEQALKGPEEALVTCRQMLR 628
Cdd:COG2956   245 D-DLLLALADLLERKEGLEAALALLERQLR 273
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 662-879 2.10e-06

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 51.52  E-value: 2.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 662 RGGGLEKDGSLGEGlTMKKQSGMHLTLPDAhDADSGSRRASSIAASRLE-------EAMS-ELTMPSSVLKQGP------ 727
Cdd:TIGR00990 276 RPAGLEDSNELDEE-TGNGQLQLGLKSPES-KADESYEEAARAFEKALDlgklgekEAIAlNLRGTFKCLKGKHlealad 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 728 ----MQLWTTLEQIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGV 803
Cdd:TIGR00990 354 lsksIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFI 433

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622855211 804 RIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIP 879
Cdd:TIGR00990 434 FSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPMYMNVLP 509
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 506-872 1.30e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 1.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 506 LKSKQDElhrKALQTLERAQQLAPGDPQViLYVSLQLALVR-QISSAMEQLQEALKVCKDDAHALHLLALLFSAQKHHQH 584
Cdd:TIGR02917 238 IEAGEFE---EAEKHADALLKKAPNSPLA-HYLKALVDFQKkNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQ 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 585 ALDVVNMAITEHPENFNLMFTKVKLEQALKGPEEALVTCRQMLRLwqtlysfsqlgDSGSPEGFQTPqrnvcnSEIYRGG 664
Cdd:TIGR02917 314 AYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGL-----------DPDDPAALSLL------GEAYLAL 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 665 G--------LEKDGSLGEGLTMKK-QSGM-HLTLPDAHDADsgsrrASSIAASRLEEAM--SELTMPSSVLKQGPM---- 728
Cdd:TIGR02917 377 GdfekaaeyLAKATELDPENAAARtQLGIsKLSQGDPSEAI-----ADLETAAQLDPELgrADLLLILSYLRSGQFdkal 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 729 --------------QLWTTLEQIWLQAAELFMEQKHLKEAgfcIQEAAGLFPTSHSVLymrgRLAEVKGSLEEAKQLYKE 794
Cdd:TIGR02917 452 aaakklekkqpdnaSLHNLLGAIYLGKGDLAKAREAFEKA---LSIEPDFFPAAANLA----RIDIQEGNPDDAIQRFEK 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 795 ALTVNPDGVRIMHSLGLMLSRLGHKS---------------------------LAQK-------VLRDAVERQSTCHEAW 840
Cdd:TIGR02917 525 VLTIDPKNLRAILALAGLYLRTGNEEeavawlekaaelnpqeiepalalaqyyLGKGqlkkalaILNEAADAAPDSPEAW 604

                         410       420       430
                  ....*....|....*....|....*....|..
gi 1622855211 841 QGLGEVLQAQGQNEAAVDCFLTALELEASSPV 872
Cdd:TIGR02917 605 LMLGRAQLAAGDLNKAVSSFKKLLALQPDSAL 636
TPR_11 pfam13414
TPR repeat;
782-817 3.10e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.30  E-value: 3.10e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1622855211 782 KGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLG 817
Cdd:pfam13414   7 QGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
 
Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 9-403 3.85e-150

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 447.30  E-value: 3.85e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211   9 SHLKVESELERCRAEGHWDRMPELVRQLQSLSMPggggnrrgipsaaftfpdTDDFGKLLLAEALLEQCLKENHAKIKDS 88
Cdd:pfam19440   8 SGYRLETEIERCRSECQWDKVPELVEQLKAKRIA------------------NDDMANLLLGEGKLEQYLKENPPILENS 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211  89 IpllEKNEPKMSEAKNYLSSILNHGRLTPQYMCEAMLILGKLHYVEGSYRDAISMYARAGIDDVSMENKPLYQMRLLSEA 168
Cdd:pfam19440  70 T---EKNQPKLSEAKKHLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEA 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 169 FVIKGLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLKGCHPV-DYELTYFLEAALQSA 247
Cdd:pfam19440 147 YAIKGLCLEKQAVSSSSRVRLAEREEEMITCYEKAGDIALLYLQELERINSNTQNRSPKPGPPSqEQELGFFLETALQRA 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 248 YVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEE-NSFATQA--- 323
Cdd:pfam19440 227 YVLYFKKGNLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPlKGTNTKNytp 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 324 LRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRAVSLQNAAAIYDLLSITLGRRGQYVMLSECL 403
Cdd:pfam19440 307 SRKPRVYSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 734-871 1.06e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 94.29  E-value: 1.06e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 734 LEQIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLML 813
Cdd:COG3914    77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622855211 814 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 871
Cdd:COG3914   157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNA 214
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
736-867 2.48e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 82.36  E-value: 2.48e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 736 QIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 815
Cdd:COG0457     9 EAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQA 88

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1622855211 816 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELE 867
Cdd:COG0457    89 LGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 736-868 3.41e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 73.30  E-value: 3.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 736 QIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 815
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1622855211 816 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEA 868
Cdd:COG4783    85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 704-873 2.45e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.38  E-value: 2.45e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 704 IAASRLEEAMSELtmpSSVLKQGPMQlwttlEQIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKG 783
Cdd:COG2956    87 LKAGLLDRAEELL---EKLLELDPDD-----AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQG 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 784 SLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTA 863
Cdd:COG2956   159 DYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKA 238

                         170
                  ....*....|
gi 1622855211 864 LELEASSPVL 873
Cdd:COG2956   239 LELDPSDDLL 248
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
736-868 1.14e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.58  E-value: 1.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 736 QIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 815
Cdd:COG0457    43 EALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLE 122

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1622855211 816 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEA 868
Cdd:COG0457   123 LGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAAL 175
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 735-867 1.38e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.07  E-value: 1.38e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 735 EQIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLS 814
Cdd:COG2956    76 AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1622855211 815 RLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELE 867
Cdd:COG2956   156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD 208
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
764-871 2.20e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.81  E-value: 2.20e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 764 LFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGL 843
Cdd:COG0457     3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                          90       100
                  ....*....|....*....|....*...
gi 1622855211 844 GEVLQAQGQNEAAVDCFLTALELEASSP 871
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALELDPDDA 110
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 684-871 3.61e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.49  E-value: 3.61e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 684 MHLTLPDAHDADSGSRRASSIAASRLEEAmsELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQKHLKEAGFCIQEAAG 763
Cdd:COG3914     2 AAAALLALAALAAAALLAAAAAAELALAA--ELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 764 LFPTSHSVLYMRGRLaevkgslEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGL 843
Cdd:COG3914    80 LLELAALLLQALGRY-------EEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNL 152

                         170       180
                  ....*....|....*....|....*...
gi 1622855211 844 GEVLQAQGQNEAAVDCFLTALELEASSP 871
Cdd:COG3914   153 GEALRRLGRLEEAIAALRRALELDPDNA 180
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 770-871 2.55e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 65.21  E-value: 2.55e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 770 SVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQA 849
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90       100
                  ....*....|....*....|..
gi 1622855211 850 QGQNEAAVDCFLTALELEASSP 871
Cdd:COG4783    85 AGDYDEALALLEKALKLDPEHP 106
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 735-865 2.97e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 2.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 735 EQIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLS 814
Cdd:COG2956   144 AHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYE 223

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1622855211 815 RLGHKSLAQKVLRDAVERQSTcHEAWQGLGEVLQAQGQNEAAVDCFLTALE 865
Cdd:COG2956   224 KLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLR 273
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 782-867 5.84e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 61.51  E-value: 5.84e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 782 KGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFL 861
Cdd:COG5010    67 LGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQ 146


                  ....*.
gi 1622855211 862 TALELE 867
Cdd:COG5010   147 RALGTS 152
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 753-866 1.26e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.02  E-value: 1.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 753 EAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVER 832
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1622855211 833 QSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALEL 866
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 736-871 2.53e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.05  E-value: 2.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 736 QIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 815
Cdd:COG2956    43 EAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQ 122

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622855211 816 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 871
Cdd:COG2956   123 EGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCA 178
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 738-866 4.01e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 61.67  E-value: 4.01e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 738 WLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLG 817
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1622855211 818 HKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALEL 866
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 736-877 1.50e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.55  E-value: 1.50e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 736 QIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 815
Cdd:COG3914   113 EALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQD 192

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622855211 816 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVL-PFSI 877
Cdd:COG3914   193 LGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELsPFAL 255
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
782-869 1.80e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 55.56  E-value: 1.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 782 KGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKvLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFL 861
Cdd:COG3063     5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83


                  ....*...
gi 1622855211 862 TALELEAS 869
Cdd:COG3063    84 RALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 773-871 8.93e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.43  E-value: 8.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 773 YMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQ 852
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                          90
                  ....*....|....*....
gi 1622855211 853 NEAAVDCFLTALELEASSP 871
Cdd:COG2956    92 LDRAEELLEKLLELDPDDA 110
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 736-832 3.85e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.70  E-value: 3.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 736 QIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 815
Cdd:COG4235    18 EGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQ 97

                          90
                  ....*....|....*..
gi 1622855211 816 LGHKSLAQKVLRDAVER 832
Cdd:COG4235    98 QGDYAEAIAAWQKLLAL 114
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
744-833 3.07e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.01  E-value: 3.07e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 744 LFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQlYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQ 823
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|
gi 1622855211 824 KVLRDAVERQ 833
Cdd:COG3063    80 AYLERALELD 89
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 367-628 1.00e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.27  E-value: 1.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 367 EQEEDRAVS-LQNAAAI---YDLLSITLG----RRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLR 438
Cdd:COG2956    21 NGQPDKAIDlLEEALELdpeTVEAHLALGnlyrRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 439 ECVKLRPSDPTVPLMAAKVCIGSLHWlEEAERFAMMVISLGEEAGEFlpkgYLALGLTYslqatdatLKSKQDElhrKAL 518
Cdd:COG2956   101 KLLELDPDDAEALRLLAEIYEQEGDW-EKAIEVLERLLKLGPENAHA----YCELAELY--------LEQGDYD---EAI 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 519 QTLERAQQLAPGDPQVILYVSLQLALVRQISSAMEQLQEALKVCKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPE 598
Cdd:COG2956   165 EALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244

                         250       260       270
                  ....*....|....*....|....*....|
gi 1622855211 599 NfNLMFTKVKLEQALKGPEEALVTCRQMLR 628
Cdd:COG2956   245 D-DLLLALADLLERKEGLEAALALLERQLR 273
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
796-867 1.01e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.78  E-value: 1.01e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622855211 796 LTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELE 867
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELD 72
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 662-879 2.10e-06

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 51.52  E-value: 2.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 662 RGGGLEKDGSLGEGlTMKKQSGMHLTLPDAhDADSGSRRASSIAASRLE-------EAMS-ELTMPSSVLKQGP------ 727
Cdd:TIGR00990 276 RPAGLEDSNELDEE-TGNGQLQLGLKSPES-KADESYEEAARAFEKALDlgklgekEAIAlNLRGTFKCLKGKHlealad 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 728 ----MQLWTTLEQIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGV 803
Cdd:TIGR00990 354 lsksIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFI 433

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622855211 804 RIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIP 879
Cdd:TIGR00990 434 FSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPMYMNVLP 509
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 417-629 3.75e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 49.34  E-value: 3.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 417 WYQVALSMVACGKSAYAVSLLRECVKLRPSDPtvplmAAKVCIGSLHW----LEEAERFAMMVISLGEEAgeflPKGYLA 492
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETV-----EAHLALGNLYRrrgeYDRAIRIHQKLLERDPDR----AEALLE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 493 LGLTY--------------SLQATDATLKSKQDEL---------HRKALQTLERAQQLAPGDPQVILYVSLQLALVRQIS 549
Cdd:COG2956    82 LAQDYlkaglldraeelleKLLELDPDDAEALRLLaeiyeqegdWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYD 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 550 SAMEQLQEALKVCKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQALKGPEEALVTCRQMLRL 629
Cdd:COG2956   162 EAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALEL 241
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 460-629 1.10e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 49.22  E-value: 1.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 460 GSLHWLEEAERFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDelHRKALQTLERAQQLAPGDPQVILYVS 539
Cdd:COG3914    42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--YEEALALYRRALALNPDNAEALFNLG 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 540 LQLALVRQISSAMEQLQEALKVCKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQALKGPEEA 619
Cdd:COG3914   120 NLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199

                         170
                  ....*....|
gi 1622855211 620 LVTCRQMLRL 629
Cdd:COG3914   200 IAAYRRALEL 209
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
729-865 1.30e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 47.22  E-value: 1.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 729 QLWTTLEQIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHS 808
Cdd:COG4785    67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622855211 809 LGLMLSRLGHKSLAQKVLRDAVERQSTCHEA--WQGL------------------GEVLQAQGQNEAAVDCFLTALE 865
Cdd:COG4785   147 RGIALYYLGRYELAIADLEKALELDPNDPERalWLYLaerkldpekalallledwATAYLLQGDTEEARELFKLALA 223
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 787-871 2.99e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.61  E-value: 2.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 787 EAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALEL 866
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                  ....*
gi 1622855211 867 EASSP 871
Cdd:COG4235    81 DPDNP 85
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 506-872 1.30e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 1.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 506 LKSKQDElhrKALQTLERAQQLAPGDPQViLYVSLQLALVR-QISSAMEQLQEALKVCKDDAHALHLLALLFSAQKHHQH 584
Cdd:TIGR02917 238 IEAGEFE---EAEKHADALLKKAPNSPLA-HYLKALVDFQKkNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQ 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 585 ALDVVNMAITEHPENFNLMFTKVKLEQALKGPEEALVTCRQMLRLwqtlysfsqlgDSGSPEGFQTPqrnvcnSEIYRGG 664
Cdd:TIGR02917 314 AYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGL-----------DPDDPAALSLL------GEAYLAL 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 665 G--------LEKDGSLGEGLTMKK-QSGM-HLTLPDAHDADsgsrrASSIAASRLEEAM--SELTMPSSVLKQGPM---- 728
Cdd:TIGR02917 377 GdfekaaeyLAKATELDPENAAARtQLGIsKLSQGDPSEAI-----ADLETAAQLDPELgrADLLLILSYLRSGQFdkal 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 729 --------------QLWTTLEQIWLQAAELFMEQKHLKEAgfcIQEAAGLFPTSHSVLymrgRLAEVKGSLEEAKQLYKE 794
Cdd:TIGR02917 452 aaakklekkqpdnaSLHNLLGAIYLGKGDLAKAREAFEKA---LSIEPDFFPAAANLA----RIDIQEGNPDDAIQRFEK 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 795 ALTVNPDGVRIMHSLGLMLSRLGHKS---------------------------LAQK-------VLRDAVERQSTCHEAW 840
Cdd:TIGR02917 525 VLTIDPKNLRAILALAGLYLRTGNEEeavawlekaaelnpqeiepalalaqyyLGKGqlkkalaILNEAADAAPDSPEAW 604

                         410       420       430
                  ....*....|....*....|....*....|..
gi 1622855211 841 QGLGEVLQAQGQNEAAVDCFLTALELEASSPV 872
Cdd:TIGR02917 605 LMLGRAQLAAGDLNKAVSSFKKLLALQPDSAL 636
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
772-871 1.44e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.14  E-value: 1.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 772 LYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQG 851
Cdd:COG4785    76 YYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                          90       100
                  ....*....|....*....|
gi 1622855211 852 QNEAAVDCFLTALELEASSP 871
Cdd:COG4785   156 RYELAIADLEKALELDPNDP 175
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 803-871 2.21e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.10  E-value: 2.21e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622855211 803 VRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 871
Cdd:COG4783     4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP 72
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 736-802 4.04e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.14  E-value: 4.04e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622855211 736 QIWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDG 802
Cdd:COG4235    52 DALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 372-472 6.31e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 43.44  E-value: 6.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 372 RAVSLQ-NAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTV 450
Cdd:COG3914   103 RALALNpDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEA 182

                          90       100
                  ....*....|....*....|..
gi 1622855211 451 PLMAAKVCIgSLHWLEEAERFA 472
Cdd:COG3914   183 LNNLGNALQ-DLGRLEEAIAAY 203
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 737-866 6.39e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 42.98  E-value: 6.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 737 IWLQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSV-LYMRGRLAEVKGSLEEAKQlykeALTVNPDGVRIMHSLGLMLSR 815
Cdd:COG3071   195 LAAAYARALIALGDHDEAERLLREALKRQWDPRLVrLYGRLQGGDPAKQLKRAEK----WLKKHPNDPDLLLALGRLCLR 270

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1622855211 816 LGHKSLAQKVLRDAVERQSTChEAWQGLGEVLQAQGQNEAAVDCFLTALEL 866
Cdd:COG3071   271 NQLWGKAREYLEAALALRPSA-EAYAELARLLEQLGDPEEAAEHYRKALAL 320
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
378-560 7.38e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 42.30  E-value: 7.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 378 NAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKV 457
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 458 CIgSLHWLEEAERFAMMVISLGEEagefLPKGYLALGLTYSLQatdatlkskqdELHRKALQTLERAQQLAPGDPQVILY 537
Cdd:COG0457    86 LQ-ALGRYEEALEDYDKALELDPD----DAEALYNLGLALLEL-----------GRYDEAIEAYERALELDPDDADALYN 149

                         170       180
                  ....*....|....*....|...
gi 1622855211 538 VSLQLALVRQISSAMEQLQEALK 560
Cdd:COG0457   150 LGIALEKLGRYEEALELLEKLEA 172
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 739-832 8.99e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 8.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 739 LQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGH 818
Cdd:TIGR02917 163 LGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGE 242

                          90
                  ....*....|....
gi 1622855211 819 KSLAQKVLRDAVER 832
Cdd:TIGR02917 243 FEEAEKHADALLKK 256
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 371-457 9.62e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 9.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 371 DRAVSLQ-NAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPT 449
Cdd:COG4783    28 EKALELDpDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE 107


                  ....*...
gi 1622855211 450 VPLMAAKV 457
Cdd:COG4783   108 AYLRLARA 115
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 771-832 1.09e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.59  E-value: 1.09e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622855211 771 VLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRI---MHSLGLMLSRLGHKSLAQKVLRDAVER 832
Cdd:COG1729    32 ALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDKARATLEELIKK 96
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 514-629 1.09e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 514 HRKALQTLERAQQLAPGDPQVILYVSLQLALVRQISSAMEQLQEALKVCKDDAHALHLLALLFSAQKHHQHALDVVNMAI 593
Cdd:COG4783    20 YDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1622855211 594 TEHPENFNLMFTKVKLEQALKGPEEALVTCRQMLRL 629
Cdd:COG4783   100 KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 785-872 1.11e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.71  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 785 LEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTAL 864
Cdd:COG5010    36 NTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKAL 115


                  ....*...
gi 1622855211 865 ELEASSPV 872
Cdd:COG5010   116 ALSPDNPN 123
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 487-612 2.50e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.83  E-value: 2.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 487 PKGYLALGLTYSLQatdatlkskqdELHRKALQTLERAQQLAPGDPQVILYVSLQLALVRQISSAMEQLQEALKVCKDDA 566
Cdd:COG4235    17 AEGWLLLGRAYLRL-----------GRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1622855211 567 HALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQA 612
Cdd:COG4235    86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAEA 131
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 771-866 2.74e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 2.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 771 VLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQ 850
Cdd:TIGR02917 127 LLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSL 206

                          90
                  ....*....|....*.
gi 1622855211 851 GQNEAAVDCFLTALEL 866
Cdd:TIGR02917 207 GNIELALAAYRKAIAL 222
TPR_11 pfam13414
TPR repeat;
782-817 3.10e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.30  E-value: 3.10e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1622855211 782 KGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLG 817
Cdd:pfam13414   7 QGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 739-875 4.72e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 4.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 739 LQAAELFMEQKHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGH 818
Cdd:TIGR02917 571 LALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKN 650

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622855211 819 KSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAvdcFLTALELEASSPVLPF 875
Cdd:TIGR02917 651 YAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESA---KKIAKSLQKQHPKAAL 704
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
465-625 5.28e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.60  E-value: 5.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 465 LEEAERFAMMVISLGEEagefLPKGYLALGLTYSLQatdatlkskqdELHRKALQTLERAQQLAPGDPQVILYVSLQLAL 544
Cdd:COG0457    24 YEEAIEDYEKALELDPD----DAEALYNLGLAYLRL-----------GRYEEALADYEQALELDPDDAEALNNLGLALQA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622855211 545 VRQISSAMEQLQEALKVCKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQALKGPEEALVTCR 624
Cdd:COG0457    89 LGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLE 168


                  .
gi 1622855211 625 Q 625
Cdd:COG0457   169 K 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH