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Conserved domains on  [gi|1622850710|ref|XP_014966037|]
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3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X1 [Macaca mulatta]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
46-376 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 554.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  46 AGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPV-FFREEYML 124
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 125 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 204
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 205 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFMLEEHMDKINSCFSANTMEEIIENL 284
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 285 KQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPA 362
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPA 317
                         330
                  ....*....|....
gi 1622850710 363 DLKEVTDEDLNNHF 376
Cdd:pfam16113 318 TLEEVTDEMVDAYF 331
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
46-376 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 554.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  46 AGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPV-FFREEYML 124
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 125 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 204
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 205 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFMLEEHMDKINSCFSANTMEEIIENL 284
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 285 KQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPA 362
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPA 317
                         330
                  ....*....|....
gi 1622850710 363 DLKEVTDEDLNNHF 376
Cdd:pfam16113 318 TLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
34-378 1.16e-158

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 449.27  E-value: 1.16e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  34 AAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNI 113
Cdd:PRK05617    1 TEDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 114 A-PVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLG 192
Cdd:PRK05617   81 AaDRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 193 YFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKE-NIASVLENYHTESKIDRdksfmLEEHMDKINSC 271
Cdd:PRK05617  161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGAdVVDAALAAFATPAPASE-----LAAQRAWIDEC 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 272 FSANTMEEIIENLKQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLI 351
Cdd:PRK05617  236 FAGDTVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLI 315
                         330       340
                  ....*....|....*....|....*..
gi 1622850710 352 DKDQSPKWKPADLKEVTDEDLNNHFKS 378
Cdd:PRK05617  316 DKDRNPKWSPATLEDVTPEDVEAFFAP 342
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
38-222 1.53e-60

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 193.93  E-value: 1.53e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIApVF 117
Cdd:cd06558     1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEAR-AF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 196
Cdd:cd06558    79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELL 158
                         170       180
                  ....*....|....*....|....*.
gi 1622850710 197 LTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:cd06558   159 LTGRRISAEEALELGLVDEVVPDEEL 184
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
38-350 3.68e-52

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 174.20  E-value: 3.68e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIApvF 117
Cdd:COG1024     1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAAAADPEEARA--F 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 196
Cdd:COG1024    78 ARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELL 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 197 LTGFRLKGRDVYRAGIATHFVDSEKLamleedllalkspskeniasvlenyhteskidrdksfmleehmdkinscfsant 276
Cdd:COG1024   158 LTGRRIDAEEALELGLVNRVVPDDEL------------------------------------------------------ 183
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622850710 277 MEEiienlkqdgssfALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVL 350
Cdd:COG1024   184 LAA------------ALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
26-222 1.68e-15

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 75.66  E-value: 1.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  26 LRMSKHTDAAADvllekkgcagvITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRV--- 102
Cdd:TIGR01929   4 IRYEKSTDGIAK-----------ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVrgd 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 103 ---ISEAEKAKQNIAPVffreeymlNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVG 179
Cdd:TIGR01929  73 ygyIDDSGVHRLNVLDV--------QRQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGY 144
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1622850710 180 GGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:TIGR01929 145 GSSYMARIVGqKKAREIWFLCRQYDAKQALDMGLVNTVVPLADL 188
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
46-376 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 554.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  46 AGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPV-FFREEYML 124
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 125 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 204
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 205 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFMLEEHMDKINSCFSANTMEEIIENL 284
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 285 KQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPA 362
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPA 317
                         330
                  ....*....|....
gi 1622850710 363 DLKEVTDEDLNNHF 376
Cdd:pfam16113 318 TLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
34-378 1.16e-158

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 449.27  E-value: 1.16e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  34 AAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNI 113
Cdd:PRK05617    1 TEDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 114 A-PVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLG 192
Cdd:PRK05617   81 AaDRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 193 YFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKE-NIASVLENYHTESKIDRdksfmLEEHMDKINSC 271
Cdd:PRK05617  161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGAdVVDAALAAFATPAPASE-----LAAQRAWIDEC 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 272 FSANTMEEIIENLKQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLI 351
Cdd:PRK05617  236 FAGDTVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLI 315
                         330       340
                  ....*....|....*....|....*..
gi 1622850710 352 DKDQSPKWKPADLKEVTDEDLNNHFKS 378
Cdd:PRK05617  316 DKDRNPKWSPATLEDVTPEDVEAFFAP 342
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
38-377 2.32e-112

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 333.30  E-value: 2.32e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIAPVF 117
Cdd:PLN02874   13 VLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDLKMFYDGRESDDSCLEVV 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 FREeYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLAL 197
Cdd:PLN02874   92 YRM-YWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPGHLGEYLAL 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 198 TGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFmleEHMDKINSCFSANTM 277
Cdd:PLN02874  171 TGARLNGKEMVACGLATHFVPSEKLPELEKRLLNLNSGDESAVQEAIEEFSKDVQADEDSIL---NKQSWINECFSKDTV 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 278 EEIIENL----KQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRG---HDFHEGVRAVL 350
Cdd:PLN02874  248 EEIIKAFeseaSKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRKQSLAECLKKEFRLTMNILRStvsDDVYEGIRALV 327
                         330       340
                  ....*....|....*....|....*..
gi 1622850710 351 IDKDQSPKWKPADLKEVTDEDLNNHFK 377
Cdd:PLN02874  328 IDKDNAPKWNPSTLDEVTDEKVDLVFQ 354
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
28-377 5.43e-92

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 281.22  E-value: 5.43e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  28 MSKHTDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGaGGKAFCAGGDIR-VISEA 106
Cdd:PLN02988    1 MAVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKG-HGRAFCAGGDVAaVVRDI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 107 EKAKQNIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR 186
Cdd:PLN02988   80 EQGNWRLGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSR 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 187 LQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFmleEHMD 266
Cdd:PLN02988  160 LPGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFASTILDAYTQHPRLKPQSAY---HRLD 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 267 KINSCFSANTMEEIIENLK----QDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGH-- 340
Cdd:PLN02988  237 VIDRCFSRRTVEEIISALEreatQEADGWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEis 316
                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1622850710 341 -DFHEGVRAVLIDKDQSPKWKPADLKEVTDEDLNNHFK 377
Cdd:PLN02988  317 kDFVEGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFE 354
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
18-383 1.69e-84

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 262.99  E-value: 1.69e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  18 RTNTILHHLRMS------KHTDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGg 91
Cdd:PLN02851   18 RFGSVSYGRSFSalpnyaANDDLQDQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG- 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  92 KAFCAGGDIRVISEA-EKAKQNIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPET 170
Cdd:PLN02851   97 RAFCSGADVVSLYHLiNEGNVEECKLFFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEV 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 171 AIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHte 250
Cdd:PLN02851  177 QMGFHPDAGASYYLSRLPGYLGEYLALTGQKLNGVEMIACGLATHYCLNARLPLIEERLGKLLTDDPAVIEDSLAQYG-- 254
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 251 SKIDRDKSFMLEEhMDKINSCFSANTMEEIIENLKQDGSS----FALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVL 326
Cdd:PLN02851  255 DLVYPDKSSVLHK-IETIDKCFGHDTVEEIIEALENEAASsydeWCKKALKKIKEASPLSLKVTLQSIREGRFQTLDQCL 333
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 327 TMEYRLSQACMR---GHDFHEGVRAVLIDKDQSPKWKPADLKEVTDEDLNNHFKSLGSND 383
Cdd:PLN02851  334 AREYRISLCGVSkwvSGDFCEGVRARLVDKDFAPKWDPPSLGEVSKDMVDCYFTPLDESE 393
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
5-379 4.31e-81

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 253.84  E-value: 4.31e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710   5 EVWRLmsrfnAFKRTntiLHHLRMSKHtDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLI 84
Cdd:PLN02157   15 KLWRF-----GYRRS---FCSLKLTPE-DLDYQVLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFV 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  85 IIKGAGgKAFCAGGDIRVISEAE-KAKQNIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKC 163
Cdd:PLN02157   86 MMKGSG-RAFCAGGDIVSLYHLRkRGSPDAIREFFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRT 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 164 LFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASV 243
Cdd:PLN02157  165 IFATPETIIGFHPDAGASFNLSHLPGRLGEYLGLTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLKKLLTDDPSVVESC 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 244 LENYhteSKIDRDKSFMLEEHMDKINSCFSANTMEEIIENLKQDGS----SFALEQLKVINKMSPTSLKITLRQLMEGSS 319
Cdd:PLN02157  245 LEKC---AEVAHPEKTGVIRRIDLLEKCFSHDTVEEIIDSLEIEAGrrkdTWCITTLRRLKESSPLSLKVALRSIREGRL 321
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622850710 320 KTLQEVLTMEYRLSQACMRG---HDFHEGVRAVLIDKDQSPKWKPADLKEVTDEDLNNHFKSL 379
Cdd:PLN02157  322 QTLDQCLIREYRMSLQGLIGpmsGNFCEGVRARLIDKDEAPKWDPPSLEKVSEDMVDDYFCAL 384
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
38-222 1.53e-60

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 193.93  E-value: 1.53e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIApVF 117
Cdd:cd06558     1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEAR-AF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 196
Cdd:cd06558    79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELL 158
                         170       180
                  ....*....|....*....|....*.
gi 1622850710 197 LTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:cd06558   159 LTGRRISAEEALELGLVDEVVPDEEL 184
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
38-350 3.68e-52

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 174.20  E-value: 3.68e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIApvF 117
Cdd:COG1024     1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAAAADPEEARA--F 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 196
Cdd:COG1024    78 ARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELL 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 197 LTGFRLKGRDVYRAGIATHFVDSEKLamleedllalkspskeniasvlenyhteskidrdksfmleehmdkinscfsant 276
Cdd:COG1024   158 LTGRRIDAEEALELGLVNRVVPDDEL------------------------------------------------------ 183
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622850710 277 MEEiienlkqdgssfALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVL 350
Cdd:COG1024   184 LAA------------ALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
34-350 9.61e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 131.53  E-value: 9.61e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  34 AAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKA-KQN 112
Cdd:PRK06688    3 MVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGR-AFSAGGDIKDFPKAPPKpPDE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 113 IAPVFfreeyMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLqgkLG 192
Cdd:PRK06688   82 LAPVN-----RFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRL---IG 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 193 YF----LALTGFRLKGRDVYRAGIATHFVDSEKLAmleedllalkspskeniasvlenyhteskidrdksfmleehmdki 268
Cdd:PRK06688  154 RAraaeMLLLGEPLSAEEALRIGLVNRVVPAAELD--------------------------------------------- 188
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 269 nscfsantmeeiienlkqdgsSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRA 348
Cdd:PRK06688  189 ---------------------AEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATA 247

                  ..
gi 1622850710 349 VL 350
Cdd:PRK06688  248 FI 249
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
37-279 4.19e-27

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 108.30  E-value: 4.19e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  37 DVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIS-----EAEKAKQ 111
Cdd:PRK05809    5 NVILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKdlneeEGRKFGL 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 112 NIAPVFFREEYMlnnavgscQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-K 190
Cdd:PRK05809   85 LGNKVFRKLENL--------DKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGpG 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 191 LGYFLALTGFRLKGRDVYRAGIATHFVDSEKLaMLEEDLLALKSPSKENIASVL--ENYHTESKIDRDKSFMLEEhmDKI 268
Cdd:PRK05809  157 KAKELIYTGDMINAEEALRIGLVNKVVEPEKL-MEEAKALANKIAANAPIAVKLckDAINRGMQVDIDTAVAIEA--EDF 233
                         250
                  ....*....|.
gi 1622850710 269 NSCFSANTMEE 279
Cdd:PRK05809  234 GECFSTEDQTE 244
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
47-245 3.09e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 105.97  E-value: 3.09e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  47 GVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDI--RVISEAEKAKQNIAPVffrEEYMl 124
Cdd:PRK07657   15 VKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLkeRAGMNEEQVRHAVSLI---RTTM- 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 125 nNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLK 203
Cdd:PRK07657   91 -EMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVgRAKELIYTGRRIS 169
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1622850710 204 GRDVYRAGIATHFVDSEKLAMLEEDL---LALKSP-----SKENIASVLE 245
Cdd:PRK07657  170 AQEAKEIGLVEFVVPAHLLEEKAIEIaekIASNGPiavrqAKEAISNGIQ 219
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
28-231 1.04e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 104.40  E-value: 1.04e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  28 MSKHTDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDirvISEAE 107
Cdd:PRK06127    3 MSSISSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGAD---ISQFE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 108 KAKQNIAPVFFREEYMLN--NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfpdvGGGY-FL 184
Cdd:PRK06127   80 ESRSDAEAVAAYEQAVEAaqAALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGL----GYGYdGV 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1622850710 185 PRLQGKLGYFLA----LTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLA 231
Cdd:PRK06127  156 KNLVDLVGPSAAkdlfYTARRFDAAEALRIGLVHRVTAADDLETALADYAA 206
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
41-222 1.08e-25

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 103.98  E-value: 1.08e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  41 EKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGaGGKAFCAGGDIRVISEAEKAKQNIapvfFRE 120
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQAL----YRE 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 121 EYM-LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALT 198
Cdd:pfam00378  76 NVLdLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHsKAMEMLLL 155
                         170       180
                  ....*....|....*....|....
gi 1622850710 199 GFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:pfam00378 156 GRRISAQEALKWGLVDKVVPEDQL 179
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
38-212 1.41e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 103.71  E-value: 1.41e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISE--AEKAKQNIAP 115
Cdd:PRK06072    2 IKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEG-RAFCVGADLSEFAPdfAIDLRETFYP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 116 VFfREeymlnnaVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFL 195
Cdd:PRK06072   81 II-RE-------IRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEI 152
                         170
                  ....*....|....*..
gi 1622850710 196 ALTGFRLKGRDVYRAGI 212
Cdd:PRK06072  153 LVLGGEFTAEEAERWGL 169
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
32-220 6.01e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 102.44  E-value: 6.01e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  32 TDAAADVLLEKKGCAGV--ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGaGGKAFCAGGDIRVISEAEKA 109
Cdd:PRK08138    2 MSTATDVVLLERPADGValLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTG-GEKVFAAGADIKEFATAGAI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 110 KqniapVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189
Cdd:PRK08138   81 E-----MYLRHTERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVG 155
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622850710 190 KL-GYFLALTGFRLKGRDVYRAGIATHFVDSE 220
Cdd:PRK08138  156 KFkAMRMALTGCMVPAPEALAIGLVSEVVEDE 187
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
38-199 1.29e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 101.37  E-value: 1.29e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPV- 116
Cdd:PRK05980    5 VLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADVALRd 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 117 FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFL 195
Cdd:PRK05980   85 FVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGrKRALEL 164

                  ....
gi 1622850710 196 ALTG 199
Cdd:PRK05980  165 LLTG 168
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
38-245 1.30e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 101.27  E-value: 1.30e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRviSEAEKAKQNIAPVF 117
Cdd:PRK06494    6 STVERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLK--EQAAGGKRGWPESG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 FreeymlnnavGS------CQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR---LQ 188
Cdd:PRK06494   84 F----------GGltsrfdLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRqigLK 153
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622850710 189 GKLGYFlaLTGFRLKGRDVYRAGIATHFV-DSEKLAMLE---EDLLALkSP-----SKENIASVLE 245
Cdd:PRK06494  154 RAMGMI--LTGRRVTAREGLELGFVNEVVpAGELLAAAErwaDDILAC-SPlsiraSKQAVYRGLE 216
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
38-231 3.00e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 100.12  E-value: 3.00e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRviseaEKAKQNIAPVf 117
Cdd:PRK05862    6 ILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGS-EKAFAAGADIK-----EMADLSFMDV- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 FREEYMLN-NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF-L 195
Cdd:PRK05862   79 YKGDYITNwEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMdL 158
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1622850710 196 ALTGFRLKGRDVYRAGIATHFVDSEKLamLEEDLLA 231
Cdd:PRK05862  159 CLTGRMMDAAEAERAGLVSRVVPADKL--LDEALAA 192
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
40-245 1.16e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 90.46  E-value: 1.16e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  40 LEKKGCAGVITLNRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVI------SEAEKAKQNI 113
Cdd:PRK07658    6 VRVEDHVAVITLNHPP-ANALSSQVLHELSELLDQVEKDDNVRVVVIHGEG-RFFSAGADIKEFtsvteaEQATELAQLG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 114 APVFFREEymlnnavgSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-G 192
Cdd:PRK07658   84 QVTFERVE--------KFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAkA 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622850710 193 YFLALTGFRLKGRDVYRAGIATHFVDSEKLamLEEDL-----LALKSPskENIASVLE 245
Cdd:PRK07658  156 LEMMLTSEPITGAEALKWGLVNGVFPEETL--LDDAKklakkIAGKSP--ATTRAVLE 209
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
48-235 2.14e-20

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 89.37  E-value: 2.14e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  48 VITLNRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEK------AKQNIAPVFFree 121
Cdd:PRK06495   16 VVTLDNPP-VNALSRELRDELIAVFDEISERPDVRVVVLTGAG-KVFCAGADLKGRPDVIKgpgdlrAHNRRTRECF--- 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 122 ymlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfpdVGGGYFLPRLQGK-LGYFLALTGF 200
Cdd:PRK06495   91 ----HAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLFGHsLTRRMMLTGY 163
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1622850710 201 RLKGRDVYRAGIATHFVDSEKL---AMLEEDLLALKSP 235
Cdd:PRK06495  164 RVPAAELYRRGVIEACLPPEELmpeAMEIAREIASKSP 201
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
38-236 7.85e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 88.06  E-value: 7.85e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDI---RVISEAEKAKQNIA 114
Cdd:PRK05995    6 LEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAG-KAFCAGADLnwmKKMAGYSDDENRAD 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 115 PVFFREeyMLNnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVgggyFLPRLQGKLG-- 192
Cdd:PRK05995   85 ARRLAD--MLR-AIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPAT----ISPYVIRAMGer 157
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1622850710 193 ----YFlaLTGFRLKGRDVYRAGIATHFVDSEKL-AMLEEDLLAL--KSPS 236
Cdd:PRK05995  158 aarrYF--LTAERFDAAEALRLGLVHEVVPAEALdAKVDELLAALvaNSPQ 206
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
38-222 8.61e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 87.72  E-value: 8.61e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISE------AEKAKQ 111
Cdd:PRK06190    6 LLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGA-DPAFCAGLDLKELGGdgsaygAQDALP 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 112 NIAPvffreeymlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-K 190
Cdd:PRK06190   85 NPSP-----------AWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGiG 153
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622850710 191 LGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK06190  154 RARRMSLTGDFLDAADALRAGLVTEVVPHDEL 185
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
38-226 1.22e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 87.09  E-value: 1.22e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEA--EKAKQNIAP 115
Cdd:PRK05870    5 VLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAG-KAFCAGADLTALGAApgRPAEDGLRR 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 116 VFfrEEYMlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYF 194
Cdd:PRK05870   84 IY--DGFL---AVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGpQVARA 158
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622850710 195 LALTGFRLKGRDVYRAGIATHFVDSEKLAMLE 226
Cdd:PRK05870  159 ALLFGMRFDAEAAVRHGLALMVADDPVAAALE 190
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
49-235 1.57e-19

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 87.13  E-value: 1.57e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  49 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRviseaEKAKQNIAPVFFREEYMLNNAV 128
Cdd:PRK09674   15 LTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNA-RFFAAGADLN-----EMAEKDLAATLNDPRPQLWQRL 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 129 GSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDV 207
Cdd:PRK09674   89 QAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKsLASQMVLTGESITAQQA 168
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1622850710 208 YRAGIATHFVDSE---KLAMLEEDLLALKSP 235
Cdd:PRK09674  169 QQAGLVSEVFPPEltlERALQLASKIARHSP 199
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
31-168 3.60e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 86.20  E-value: 3.60e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  31 HTDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAK 110
Cdd:PRK06144    3 MTTSTDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAE 82
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622850710 111 QNIAPVFFREEYMlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 168
Cdd:PRK06144   83 DAVAYERRIDRVL--GALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP 138
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
49-222 5.12e-19

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 85.90  E-value: 5.12e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  49 ITLNRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPVFF---REEYMLN 125
Cdd:PRK03580   16 ITLDRPK-ANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFaglTEIFDLD 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 126 navgscqKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKLGYFLA----LTGFR 201
Cdd:PRK03580   95 -------KPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPK---RLPPAIAnemvMTGRR 164
                         170       180
                  ....*....|....*....|.
gi 1622850710 202 LKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK03580  165 MDAEEALRWGIVNRVVPQAEL 185
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
49-235 5.20e-19

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 86.11  E-value: 5.20e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  49 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISE-------------AEKAKQNIAp 115
Cdd:PLN02664   21 LNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAG-DHFCSGIDLKTLNSiseqsssgdrgrsGERLRRKIK- 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 116 vfFREEYMlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLPRLQGKLGYF- 194
Cdd:PLN02664   99 --FLQDAI--TAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGT---LQRLPSIVGYGn 171
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1622850710 195 ---LALTGFRLKGRDVYRAG-IATHFVDSEKL---AMLEEDLLALKSP 235
Cdd:PLN02664  172 ameLALTGRRFSGSEAKELGlVSRVFGSKEDLdegVRLIAEGIAAKSP 219
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
38-222 5.33e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 80.01  E-value: 5.33e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLN-MIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAkQNIAPV 116
Cdd:PRK09245    5 LLVERDGHIVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAG-TAFSSGGNVKDMRARVGA-FGGSPA 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 117 FFREEY-----MLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-K 190
Cdd:PRK09245   83 DIRQGYrhgiqRIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGmA 162
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622850710 191 LGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK09245  163 RAAEMAFTGDAIDAATALEWGLVSRVVPADQL 194
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
35-218 2.05e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 78.22  E-value: 2.05e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  35 AADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAKQnia 114
Cdd:PRK07799    4 GPHALVEQRGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGG-AFCAGMDLKAATKKPPGDS--- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 115 pvfFRE--------EYMLNNAvgSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdVGGGYFlpR 186
Cdd:PRK07799   80 ---FKDgsydpsriDALLKGR--RLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFP-MGGSAV--R 151
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1622850710 187 LQGKLGYFLA----LTGFRLKGRDVYRAGIATHFVD 218
Cdd:PRK07799  152 LVRQIPYTVAcdllLTGRHITAAEAKEIGLIGHVVP 187
PLN02600 PLN02600
enoyl-CoA hydratase
48-217 2.64e-16

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 77.92  E-value: 2.64e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  48 VITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRV-----ISEAEKAKQNIAPVFfreey 122
Cdd:PLN02600    7 ELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKErrkmsPSEVQKFVNSLRSTF----- 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 123 mlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFR 201
Cdd:PLN02600   82 ---SSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRsRAKELIFTGRR 158
                         170
                  ....*....|....*.
gi 1622850710 202 LKGRDVYRAGIATHFV 217
Cdd:PLN02600  159 IGAREAASMGLVNYCV 174
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
38-242 1.13e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 76.22  E-value: 1.13e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDpETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIAPVF 117
Cdd:PRK07659    8 VVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAES-SAHIVVLRGNG-RGFSAGGDIKMMLSSNDESKFDGVMN 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 FREEYMLnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKLGYFLA- 196
Cdd:PRK07659   86 TISEIVV--TLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQK---RVGENKAk 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1622850710 197 ---LTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLA-LKSPSKENIAS 242
Cdd:PRK07659  161 qiiWEGKKLSATEALDLGLIDEVIGGDFQTAAKQKISEwLQKPLKAMIET 210
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
48-236 1.48e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 75.90  E-value: 1.48e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  48 VITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDI---RVISEAEKAKQNIAPVFF---REE 121
Cdd:PRK06210   18 VITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGA-GRGFCAGADMgelQTIDPSDGRRDTDVRPFVgnrRPD 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 122 YMLNNA-VGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF-LALTG 199
Cdd:PRK06210   97 YQTRYHfLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANALdLLLSA 176
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1622850710 200 FRLKGRDVYRAGIATHFVDSEKL--AMLE--EDLLALKSPS 236
Cdd:PRK06210  177 RTFYAEEALRLGLVNRVVPPDELmeRTLAyaEDLARNVSPA 217
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
26-222 1.68e-15

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 75.66  E-value: 1.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  26 LRMSKHTDAAADvllekkgcagvITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRV--- 102
Cdd:TIGR01929   4 IRYEKSTDGIAK-----------ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVrgd 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 103 ---ISEAEKAKQNIAPVffreeymlNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVG 179
Cdd:TIGR01929  73 ygyIDDSGVHRLNVLDV--------QRQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGY 144
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1622850710 180 GGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:TIGR01929 145 GSSYMARIVGqKKAREIWFLCRQYDAKQALDMGLVNTVVPLADL 188
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
49-189 2.63e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 75.81  E-value: 2.63e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  49 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQNIAPVFFREEYM----- 123
Cdd:PRK08260   17 ITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGA-GRAFCAGADLSAGGNTFDLDAPRTPVEADEEDRadpsd 95
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622850710 124 ---------LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189
Cdd:PRK08260   96 dgvrdgggrVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVG 170
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
34-213 2.84e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 75.03  E-value: 2.84e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  34 AAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEK----- 108
Cdd:PRK08252    1 MSDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGG-TFCAGMDLKAFARGERpsipg 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 109 ---AKQNIAPVffreeymlnnavgscQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLP 185
Cdd:PRK08252   80 rgfGGLTERPP---------------RKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGG---LL 141
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622850710 186 RLQGKLGYFLA----LTGFRLKGRDVYRAGIA 213
Cdd:PRK08252  142 RLPRRIPYHIAmelaLTGDMLTAERAHELGLV 173
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
35-275 3.20e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 75.03  E-value: 3.20e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  35 AADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEaekaKQNIA 114
Cdd:PRK07511    2 SAELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGG-FFCAGGNLNRLLE----NRAKP 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 115 PVFFREEY-MLNN---AVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR-LQG 189
Cdd:PRK07511   77 PSVQAASIdGLHDwirAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARaLPR 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 190 KLGYFLALTGFRLKGRDVYRAGIATHFVD-----SEKLAMLEEdlLALKSP-SKENIASVLENYHTESkidrdksfmLEE 263
Cdd:PRK07511  157 QLATELLLEGKPISAERLHALGVVNRLAEpgqalAEALALADQ--LAAGSPnALARIKSLIADAPEAT---------LAA 225
                         250
                  ....*....|..
gi 1622850710 264 HMDKINSCFSAN 275
Cdd:PRK07511  226 QLEAERDHFVAS 237
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
36-199 6.57e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 73.92  E-value: 6.57e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  36 ADVLLEKKGCAgVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKqniAP 115
Cdd:PRK06143    8 AGVTRDDRGVA-TLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQAS---AE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 116 VFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfPDVGGGYFLPRLQGKL-GYF 194
Cdd:PRK06143   84 AFISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVIHAALLPRLIGWArTRW 162

                  ....*
gi 1622850710 195 LALTG 199
Cdd:PRK06143  163 LLLTG 167
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
38-235 1.05e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 73.38  E-value: 1.05e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKK-GCAGViTLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDI-RVISEAEKAKQNIAP 115
Cdd:PRK07509    5 VSVTIEdGIADV-RLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGG-AFCAGLDVkSVASSPGNAVKLLFK 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 116 vffREEYMLNNAvgscQK----------PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLP 185
Cdd:PRK07509   83 ---RLPGNANLA----QRvslgwrrlpvPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLR 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1622850710 186 RLQGK-LGYFLALTGFRLKGRDVYRAGIATHFVDS---EKLAMLEEdlLALKSP 235
Cdd:PRK07509  156 GLVRKdVARELTYTARVFSAEEALELGLVTHVSDDplaAALALARE--IAQRSP 207
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
47-223 2.40e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 72.40  E-value: 2.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  47 GV--ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIAPVFFREEYML 124
Cdd:PRK07468   14 GVatLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLGWMRAQMTADRATRIEEARRLAMM 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 125 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 204
Cdd:PRK07468   93 LKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEANARRVFMSARLFDA 172
                         170
                  ....*....|....*....
gi 1622850710 205 RDVYRAGIATHFVDSEKLA 223
Cdd:PRK07468  173 EEAVRLGLLSRVVPAERLD 191
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
41-207 2.63e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 72.31  E-value: 2.63e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  41 EKKGCAGVITLNRPKFLNALTLNM---IRQIYSQLkkwEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIAPVF 117
Cdd:PRK06142   11 ELADHVAQVTLNRPGKGNAMNPAFwseLPEIFRWL---DADPEVRAVVLSGSG-KHFSYGIDLPAMAGVFGQLGKDGLAR 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 FREEY------MLN--NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189
Cdd:PRK06142   87 PRTDLrreilrLQAaiNAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIG 166
                         170       180
                  ....*....|....*....|
gi 1622850710 190 KlGYF--LALTgfrlkGRDV 207
Cdd:PRK06142  167 D-GHLreLALT-----GRDI 180
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
41-218 3.12e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 74.10  E-value: 3.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  41 EKKGCAGVITLNRPKF-LNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIsEAEKAKQNIAPVFFR 119
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMI-AACKTAQEVTQLSQE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 120 EEYMLNNAVGScQKPYVALIHGITMGGGVGLSVHGQFRVATE--KCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF-LA 196
Cdd:TIGR02441  97 GQEMFERIEKS-QKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALdMM 175
                         170       180
                  ....*....|....*....|..
gi 1622850710 197 LTGFRLKGRDVYRAGIATHFVD 218
Cdd:TIGR02441 176 LTGKKIRADRAKKMGIVDQLVD 197
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
38-223 4.60e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 71.48  E-value: 4.60e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEqDPETFLIIIKGAgGKAFCAGGDI--RVISEAEKA------ 109
Cdd:PRK08140    6 ILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGA-GRGFCAGQDLadRDVTPGGAMpdlges 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 110 -KQNIAPvffreeymLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQ 188
Cdd:PRK08140   84 iETFYNP--------LVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLV 155
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1622850710 189 GK---LGyfLALTGFRLKGRDVYRAGIATHFVDSEKLA 223
Cdd:PRK08140  156 GMaraLG--LALLGEKLSAEQAEQWGLIWRVVDDAALA 191
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
28-175 7.49e-14

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 71.13  E-value: 7.49e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  28 MSKHTDAAADVLLEKKGCAGVI--TLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVIse 105
Cdd:PRK08139    1 MMAPAAATEAPLLLREDRDGVAtlTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAA-GKAFCAGHDLKEM-- 77
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622850710 106 aeKAKQNIApvFFRE------EYMLnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLF 175
Cdd:PRK08139   78 --RAARGLA--YFRAlfarcsRVMQ--AIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLF 147
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
23-223 7.65e-14

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 71.15  E-value: 7.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  23 LHHLRMSKHTDAAADVLLEKKGCAGVITLNRPKFLNALTLnmirQIYSQLKKW----EQDPETFLIIIKGAGGkAFCAGG 98
Cdd:PRK08258    4 FRGSKRPLAGYEARHFLWEVDDGVATITLNRPERKNPLTF----ESYAELRDLfrelVYADDVKAVVLTGAGG-NFCSGG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  99 DIRVIseaekakqnIAPV----------FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 168
Cdd:PRK08258   79 DVHEI---------IGPLtkmdmpellaFTRMTGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFL 149
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622850710 169 ETAIGLF-PDVGGGYFLPRL--QGKLGYFLaLTGFRLKGRDVYRAGIATHFVDSEKLA 223
Cdd:PRK08258  150 FTRVGLAgADMGACALLPRIigQGRASELL-YTGRSMSAEEGERWGFFNRLVEPEELL 206
PLN02888 PLN02888
enoyl-CoA hydratase
28-222 8.03e-14

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 70.94  E-value: 8.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  28 MSKHTDAAADVLLEK-KGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEA 106
Cdd:PLN02888    1 TMTQTVSENLILVPKsRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGS-GRAFCSGVDLTAAEEV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 107 EKAK---QNIAPVFFREEymlnnavgsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYF 183
Cdd:PLN02888   80 FKGDvkdVETDPVAQMER---------CRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQK 150
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1622850710 184 LPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PLN02888  151 LSRIIGaNRAREVSLTAMPLTAETAERWGLVNHVVEESEL 190
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
38-230 8.05e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 70.54  E-value: 8.05e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKgAGGKAFCAGGDIRVISEAeKAKQNIAPVF 117
Cdd:PRK07260    4 IIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLIN-ANGKVFSVGGDLVEMKRA-VDEDDVQSLV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 FREEYM--LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYF 194
Cdd:PRK07260   82 KIAELVneISFAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGlNRATH 161
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1622850710 195 LALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLL 230
Cdd:PRK07260  162 LAMTGEALTAEKALEYGFVYRVAESEKLEKTCEQLL 197
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
38-217 2.53e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 69.28  E-value: 2.53e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLkkwEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKA-----KQN 112
Cdd:PRK08150    4 VSYELDGGVATIGLNRPAKRNALNDGLIAALRAAF---ARLPEGVRAVVLHGEGDHFCAGLDLSELRERDAGegmhhSRR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 113 IAPVFFREEYmlnnavgsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFpdVGGG--YFLPRLQGK 190
Cdd:PRK08150   81 WHRVFDKIQY--------GRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIF--VGGGgsVRVPRLIGV 150
                         170       180
                  ....*....|....*....|....*...
gi 1622850710 191 LGYF-LALTGFRLKGRDVYRAGIATHFV 217
Cdd:PRK08150  151 ARMTdMMLTGRVYDAQEGERLGLAQYLV 178
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
40-189 4.60e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 68.41  E-value: 4.60e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  40 LEKKGCAGVITLNRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPVFFR 119
Cdd:PRK09076    7 LEIDGHVAILTLNNPP-ANTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFADGDKAVAREMARRFG 85
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622850710 120 EEY-MLNNAVGscqkPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189
Cdd:PRK09076   86 EAFeALSAFRG----VSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVG 152
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
32-256 8.17e-13

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 67.78  E-value: 8.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  32 TDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAKQ 111
Cdd:PRK07827    2 TPVDTLVRYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGG-TFCAGADLSEAGGGGGDPY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 112 NIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL 191
Cdd:PRK07827   81 DAAVARAREMTALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRA 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622850710 192 G--YFlaLTGFRLKGRDVYRAGIATHFVDS--EKLAMLEEDlLALKSP-----SKE-NIASVLENYhteskiDRD 256
Cdd:PRK07827  161 AarYY--LTGEKFGAAEAARIGLVTAAADDvdAAVAALLAD-LRRGSPqglaeSKAlTTAAVLAGF------DRD 226
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
28-255 2.46e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 66.35  E-value: 2.46e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  28 MSKHtdaaadVLLEKKGCAG---VITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAG---GDIR 101
Cdd:PRK06023    1 MTDH------ILVERPGAHPgvqVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEG-CFSAGndmQDFL 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 102 VISEAEKAKQNIAPVFFReeymlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGG 181
Cdd:PRK06023   74 AAAMGGTSFGSEILDFLI-------ALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSS 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 182 YFLPRLQGKLGYF--LALtGFRLKGRDVYRAGI-----ATHFVDSEKLAMLEEdlLALKSPSKENIASVLENYHTESKID 254
Cdd:PRK06023  147 LLAPRLMGHQRAFalLAL-GEGFSAEAAQEAGLiwkivDEEAVEAETLKAAEE--LAAKPPQALQIARDLMRGPREDILA 223

                  .
gi 1622850710 255 R 255
Cdd:PRK06023  224 R 224
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
28-222 1.37e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 64.47  E-value: 1.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  28 MSKHTDAAADVLLE--KKGCAgVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISE 105
Cdd:PRK05864    1 VAGYRSTMSLVLVDhpRPEIA-LITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGA-GRGFSSGADHKSAGV 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 106 AEKAKQNIAPVF-FREEYMLNNAVGSCQK---PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLF-PDVGG 180
Cdd:PRK05864   79 VPHVEGLTRPTYaLRSMELLDDVILALRRlhqPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGL 158
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1622850710 181 GYFLPRLQGKLGYF-LALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK05864  159 SYLLPRAIGSSRAFeIMLTGRDVDAEEAERIGLVSRQVPDEQL 201
PLN02921 PLN02921
naphthoate synthase
37-189 2.11e-11

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 64.42  E-value: 2.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  37 DVLLEK---KGCAGvITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNI 113
Cdd:PLN02921   66 DIIYEKavgEGIAK-ITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGKDGYVGPDD 144
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622850710 114 APvffREEYM-LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFpDVG-GGYFLPRLQG 189
Cdd:PLN02921  145 AG---RLNVLdLQIQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSF-DAGyGSSIMARLVG 218
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
38-222 4.55e-11

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 62.83  E-value: 4.55e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDP-ETFLIIIKGAGgKAFCAG----------GDIRVISEA 106
Cdd:PRK05981    6 VTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAG-RGFCTGanlqgrgsggRESDSGGDA 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 107 EKAKQNIAPVFFReeymlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR 186
Cdd:PRK05981   85 GAALETAYHPFLR-------RLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPR 157
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1622850710 187 LQGKL-GYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK05981  158 LVGKArAMELSLLGEKLPAETALQWGLVNRVVDDAEL 194
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
46-212 6.86e-11

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 63.76  E-value: 6.86e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  46 AGVITLNRP-KFLNALTLNMIRQIYSQLKKWEQDPEtfliiIKG---AGGKA--FCAGGDIRVISEAEKAKQniAPVFFR 119
Cdd:PRK11154   16 IAVITIDVPgEKMNTLKAEFAEQVRAILKQLREDKE-----LKGvvfISGKPdnFIAGADINMLAACKTAQE--AEALAR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 120 EEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT--EKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 196
Cdd:PRK11154   89 QGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTddPKTVLGLPEVQLGLLPGSGGTQRLPRLIGvSTALDMI 168
                         170
                  ....*....|....*.
gi 1622850710 197 LTGFRLKGRDVYRAGI 212
Cdd:PRK11154  169 LTGKQLRAKQALKLGL 184
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
47-249 7.84e-11

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 61.97  E-value: 7.84e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  47 GVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK---AKQNIAPVFFReeym 123
Cdd:PRK11423   15 ATITFNNPAKRNALSKVLIDDLMQALSDLNRPEIRVVILRAPSGSKVWSAGHDIHELPSGGRdplSYDDPLRQILR---- 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 124 lnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLPRLQGKLGYFLA----LTG 199
Cdd:PRK11423   91 ---MIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSG---ILNFTNDAGFHIVkemfFTA 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622850710 200 FRLKGRDVYRAGIATHFVDSEKLAMLEEDL---LALKSP-----SKENIaSVLENYHT 249
Cdd:PRK11423  165 SPITAQRALAVGILNHVVEVEELEDFTLQMahhISEKAPlaiavIKEQL-RVLGEAHP 221
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
44-213 1.72e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 60.81  E-value: 1.72e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  44 GCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEqDPETFLIIIKGAGgKAFCAGGDIrviseaekAKQNIAPVFFREEYM 123
Cdd:PRK07854    8 GQVLTIELQRPERRNALNAELCEELREAVRKAV-DESARAIVLTGQG-TVFCAGADL--------SGDVYADDFPDALIE 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 124 LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDvggGYFLPRLQGKLGYFLA----LTG 199
Cdd:PRK07854   78 MLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALD---NWTIRRLSSLVGGGRAramlLGA 154
                         170
                  ....*....|....
gi 1622850710 200 FRLKGRDVYRAGIA 213
Cdd:PRK07854  155 EKLTAEQALATGMA 168
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
37-147 1.91e-10

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 61.06  E-value: 1.91e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  37 DVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRV------ISEAEKAK 110
Cdd:PRK07396   14 DILYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVrgyggyVDDDGVPR 93
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1622850710 111 QNIAPvffreeymLNNAVGSCQKPYVALIHGITMGGG 147
Cdd:PRK07396   94 LNVLD--------LQRLIRTCPKPVIAMVAGYAIGGG 122
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
51-235 3.16e-10

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 60.21  E-value: 3.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  51 LNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQNIAPVFFREEYMLNNAVGS 130
Cdd:PRK05674   21 LSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGR-GRHFSAGADLAWMQQSADLDYNTNLDDARELAELMYNLYR 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 131 CQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRA 210
Cdd:PRK05674  100 LKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERAARRYALTAERFDGRRAREL 179
                         170       180
                  ....*....|....*....|....*...
gi 1622850710 211 G-IATHFVDSEKLAMLEE--DLLALKSP 235
Cdd:PRK05674  180 GlLAESYPAAELEAQVEAwiANLLLNSP 207
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
27-243 4.48e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 60.06  E-value: 4.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  27 RMSKHTDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISE- 105
Cdd:PRK08272    1 IRPVDLDNLKTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGA-GKGFCAGYDLSAYAEg 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 106 --AEKAKQNIAPVFFREEY--------MLNNAVGS-----------CQKPYVALIHGITMGGGVGLSVHGQFRVATEkcl 164
Cdd:PRK08272   80 ssSGGGGGAYPGKRQAVNHlpddpwdpMIDYQMMSrfvrgfmslwhAHKPTVAKVHGYCVAGGTDIALHCDQVIAAD--- 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 165 fampETAIGLFPD-VGG----GYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLalkspskEN 239
Cdd:PRK08272  157 ----DAKIGYPPTrVWGvpatGMWAYRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLV-------ER 225

                  ....
gi 1622850710 240 IASV 243
Cdd:PRK08272  226 IAAV 229
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
38-220 1.02e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 58.43  E-value: 1.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQNIAPVF 117
Cdd:PRK06563    1 VSRERRGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAH-GEHFTAGLDLADVAPKLAAGGFPFPEG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 FREEYMLnnaVG-SCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdVGGGYFlpRLQGKLGYFLA 196
Cdd:PRK06563   80 GIDPWGT---VGrRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILP-FGGATL--RFPQAAGWGNA 153
                         170       180
                  ....*....|....*....|....*...
gi 1622850710 197 ----LTGFRLKGRDVYRAGIATHFVDSE 220
Cdd:PRK06563  154 mrylLTGDEFDAQEALRLGLVQEVVPPG 181
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
48-187 1.41e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 58.06  E-value: 1.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  48 VITLNRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKgAGGKAFCAGGDIRVISEAEKAKQNIAPVffREEYMLNNA 127
Cdd:PRK07938   14 EVTVDYPP-VNALPSAGWFALADAITAAGADPDTRVVVLR-AEGRGFNAGVDIKELQATPGFTALIDAN--RGCFAAFRA 89
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 128 VGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfpdVGGGYFLPRL 187
Cdd:PRK07938   90 VYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGA---LGAATHLQRL 146
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
49-222 3.24e-09

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 57.34  E-value: 3.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  49 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIAPVfFREEYMLNNAV 128
Cdd:PRK07327   25 IVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEG-KAFSAGGDLALVEEMADDFEVRARV-WREARDLVYNV 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 129 GSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGlfpdVGGG----YFLPRLQG--KLGYFLaLTGFRL 202
Cdd:PRK07327  103 INCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLG----VAAGdhaaIVWPLLCGmaKAKYYL-LLCEPV 177
                         170       180
                  ....*....|....*....|
gi 1622850710 203 KGRDVYRAGIATHFVDSEKL 222
Cdd:PRK07327  178 SGEEAERIGLVSLAVDDDEL 197
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
38-224 3.80e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 57.28  E-value: 3.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRviSEAEKAKQNIAPVF 117
Cdd:PRK08290    6 VRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGA-GKHFSAGHDLG--SGTPGRDRDPGPDQ 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 -------------------FREEYMLNNA--VGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfp 176
Cdd:PRK08290   83 hptlwwdgatkpgveqryaREWEVYLGMCrrWRDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI-- 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622850710 177 dVGGGYFL------PRlqgKLGYFLaLTGFRLKGRDVYRAGIATHFV-----DSEKLAM 224
Cdd:PRK08290  161 -PGVEYFAhpwelgPR---KAKELL-FTGDRLTADEAHRLGMVNRVVprdelEAETLEL 214
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
38-222 2.00e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 54.96  E-value: 2.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAG----------GDIRVISEAE 107
Cdd:PRK12478    7 LLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAG-RAFSGGydfgggfqhwGEAMMTDGRW 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 108 KAKQNIAPVFFRE-----EYMlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAI-GLFPDvggG 181
Cdd:PRK12478   86 DPGKDFAMVTAREtgptqKFM---AIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwGAYLT---G 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1622850710 182 YFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222
Cdd:PRK12478  160 MWLYRLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERL 200
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
38-189 1.20e-07

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 52.15  E-value: 1.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITL--NRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGaGGKAFCAGGDIRVISEAEKAKQNIAP 115
Cdd:PRK05869    8 VVSDGSQDAGLATLllSRPP-TNALTRQVYREIVAAANELGRRDDVAAVILYG-GHEIFSAGDDMPELRTLSAQEADTAA 85
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622850710 116 VFFREEYmlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189
Cdd:PRK05869   86 RVRQQAV---DAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAG 156
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
37-182 2.62e-07

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 51.74  E-value: 2.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  37 DVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAG-----GKAFCAGGDIRV------ISE 105
Cdd:COG0447    19 DITYHRAEGIARIAINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLTGNGpskdgGWAFCSGGDQRVrgrggyVYE 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 106 AEKAKQNIAPVffreeYMLnnaVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAmpETAiglfPDVG---GGY 182
Cdd:COG0447    99 DGVGRLNILEV-----QRL---IRFMPKPVIAMVAGWAIGGGHVLHVVCDLTIASENARFG--QTG----PDVGsfdAGY 164
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
134-189 1.45e-06

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 50.25  E-value: 1.45e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622850710 134 PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189
Cdd:PRK11730  104 PTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIG 159
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
38-189 1.56e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 49.12  E-value: 1.56e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  38 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAkqniapvf 117
Cdd:PRK08259    5 VRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGG-TFCAGADLKAVGTGRGN-------- 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 118 fREEYMLNNAVGSCQ----KPYVALIHGITMGGGVGLSVHGQFRVATEKCLFampetaiGLF------PDVGGGYF-LPR 186
Cdd:PRK08259   76 -RLHPSGDGPMGPSRmrlsKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVF-------GVFcrrwgvPLIDGGTVrLPR 147

                  ...
gi 1622850710 187 LQG 189
Cdd:PRK08259  148 LIG 150
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
49-217 2.12e-06

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 48.43  E-value: 2.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  49 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGG---DIRVISEAEKAkqniapvfFREEYMLN 125
Cdd:PRK07110   18 VTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGY-PNYFATGGtqeGLLSLQTGKGT--------FTEANLYS 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 126 NAVGsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKLGYFLA----LTGFR 201
Cdd:PRK07110   89 LALN-CPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPE---KLGLALGqemlLTARY 164
                         170
                  ....*....|....*.
gi 1622850710 202 LKGRDVYRAGIATHFV 217
Cdd:PRK07110  165 YRGAELKKRGVPFPVL 180
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
49-241 2.99e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 41.98  E-value: 2.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710  49 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETflIIIKGAGgKAFCAGGDIRVISEAEKAKQNIApvfFREE--YMLNN 126
Cdd:PRK07112   17 LQLHRPEAQNTINDRLIAECMDVLDRCEHAATI--VVLEGLP-EVFCFGADFSAIAEKPDAGRADL---IDAEplYDLWH 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850710 127 AVGScqKPYVALIH--GITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdvggGYFLPRLQGKLG----YFLALTGF 200
Cdd:PRK07112   91 RLAT--GPYVTIAHvrGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP----ACVLPFLIRRIGtqkaHYMTLMTQ 164
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1622850710 201 RLKGRDVYRAGIATHFV-DSEKLamLEEDLLALKSPSKENIA 241
Cdd:PRK07112  165 PVTAQQAFSWGLVDAYGaNSDTL--LRKHLLRLRCLNKAAVA 204
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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