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Conserved domains on  [gi|922464567|ref|XP_013632920|]
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PREDICTED: uncharacterized protein LOC106338505 [Brassica oleracea var. oleracea]

Protein Classification

MULE family transposase( domain architecture ID 20350890)

MULE (Mutator-like element) family transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0006313|GO:0003677|GO:0004803|GO:0046872|GO:0032196|GO:0015074|GO:0006310|GO:0008270
PubMed:  30988700|19018586|17130173|22474413|20615441|11774877|20215432|20885819|17165262|12151216

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_PMZ smart00575
plant mutator transposase zinc finger;
522-549 3.09e-11

plant mutator transposase zinc finger;


:

Pssm-ID: 128845  Cd Length: 28  Bit Score: 58.34  E-value: 3.09e-11
                           10        20
                   ....*....|....*....|....*...
gi 922464567   522 RTCTCRRWDLTGIPCRHALKVIQDKKLN 549
Cdd:smart00575   1 KTCSCRKFQLSGIPCRHALAAAIHIGLS 28
MULE super family cl48097
MULE transposase domain; This domain was identified by Babu and colleagues.
 282-361 6.56e-11

MULE transposase domain; This domain was identified by Babu and colleagues.


The actual alignment was detected with superfamily member pfam10551:

Pssm-ID: 463145 [Multi-domain]  Cd Length: 98  Bit Score: 59.20  E-value: 6.56e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922464567  282 YNASCVLNNNQIYPVAWGIVQVEDTDNWKWFIQRVKSDLDLKNGEG-FTLISDKQKGLIKAVEEELPHIEHRTCARHIYG 360
Cdd:pfam10551  18 FTAVGVDHHGQSFPIAFGLVSNETEESFTWLFDQLIAFRECMSGLSpQVIITDRDKALKNAINLVFPEAQHRLCIFHINK 97


                  .
gi 922464567  361 N 361
Cdd:pfam10551  98 N 98
 
Name Accession Description Interval E-value
ZnF_PMZ smart00575
plant mutator transposase zinc finger;
522-549 3.09e-11

plant mutator transposase zinc finger;


Pssm-ID: 128845  Cd Length: 28  Bit Score: 58.34  E-value: 3.09e-11
                           10        20
                   ....*....|....*....|....*...
gi 922464567   522 RTCTCRRWDLTGIPCRHALKVIQDKKLN 549
Cdd:smart00575   1 KTCSCRKFQLSGIPCRHALAAAIHIGLS 28
MULE pfam10551
MULE transposase domain; This domain was identified by Babu and colleagues.
 282-361 6.56e-11

MULE transposase domain; This domain was identified by Babu and colleagues.


Pssm-ID: 463145 [Multi-domain]  Cd Length: 98  Bit Score: 59.20  E-value: 6.56e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922464567  282 YNASCVLNNNQIYPVAWGIVQVEDTDNWKWFIQRVKSDLDLKNGEG-FTLISDKQKGLIKAVEEELPHIEHRTCARHIYG 360
Cdd:pfam10551  18 FTAVGVDHHGQSFPIAFGLVSNETEESFTWLFDQLIAFRECMSGLSpQVIITDRDKALKNAINLVFPEAQHRLCIFHINK 97


                  .
gi 922464567  361 N 361
Cdd:pfam10551  98 N 98
SWIM pfam04434
SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is ...
 515-547 4.37e-07

SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is predicted to be organized into two N-terminal beta-strands and a C-terminal alpha helix, thus possibly adopting a fold similar to that of the C2H2 zinc finger (pfam00096). SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts.


Pssm-ID: 309540  Cd Length: 38  Bit Score: 46.64  E-value: 4.37e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 922464567  515 HTVNMD-----RRTCTCRRWDLTGIPCRHALKVIQDKK 547
Cdd:pfam04434   1 YRVQLDldgleKASCSCPDFQLNGIPCKHALAVLLALG 38
IS285 COG3328
Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];
304-401 1.59e-03

Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];


Pssm-ID: 442557  Cd Length: 400  Bit Score: 41.34  E-value: 1.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922464567 304 EDTDNWKWFIQrvksdlDLKN---GEGFTLISDKQKGLIKAVEEELPHIEHRTCARHIYGNIKKLHPNK--PRFKNLFWA 378
Cdd:COG3328  207 ESAAFWLEVLR------DLKNrglKDVLLVVSDGLKGLPEAIEAVFPGARWQRCIVHKIRNSLKYVPKKdrKAVAADLKA 280

                         90       100
                 ....*....|....*....|...
gi 922464567 379 VansFNEGDYKAALKELKAFDSQ 401
Cdd:COG3328  281 I---YQAPTKEAAEAALDAFAEK 300
 
Name Accession Description Interval E-value
ZnF_PMZ smart00575
plant mutator transposase zinc finger;
522-549 3.09e-11

plant mutator transposase zinc finger;


Pssm-ID: 128845  Cd Length: 28  Bit Score: 58.34  E-value: 3.09e-11
                           10        20
                   ....*....|....*....|....*...
gi 922464567   522 RTCTCRRWDLTGIPCRHALKVIQDKKLN 549
Cdd:smart00575   1 KTCSCRKFQLSGIPCRHALAAAIHIGLS 28
MULE pfam10551
MULE transposase domain; This domain was identified by Babu and colleagues.
 282-361 6.56e-11

MULE transposase domain; This domain was identified by Babu and colleagues.


Pssm-ID: 463145 [Multi-domain]  Cd Length: 98  Bit Score: 59.20  E-value: 6.56e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922464567  282 YNASCVLNNNQIYPVAWGIVQVEDTDNWKWFIQRVKSDLDLKNGEG-FTLISDKQKGLIKAVEEELPHIEHRTCARHIYG 360
Cdd:pfam10551  18 FTAVGVDHHGQSFPIAFGLVSNETEESFTWLFDQLIAFRECMSGLSpQVIITDRDKALKNAINLVFPEAQHRLCIFHINK 97


                  .
gi 922464567  361 N 361
Cdd:pfam10551  98 N 98
SWIM pfam04434
SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is ...
 515-547 4.37e-07

SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is predicted to be organized into two N-terminal beta-strands and a C-terminal alpha helix, thus possibly adopting a fold similar to that of the C2H2 zinc finger (pfam00096). SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts.


Pssm-ID: 309540  Cd Length: 38  Bit Score: 46.64  E-value: 4.37e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 922464567  515 HTVNMD-----RRTCTCRRWDLTGIPCRHALKVIQDKK 547
Cdd:pfam04434   1 YRVQLDldgleKASCSCPDFQLNGIPCKHALAVLLALG 38
IS285 COG3328
Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];
304-401 1.59e-03

Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];


Pssm-ID: 442557  Cd Length: 400  Bit Score: 41.34  E-value: 1.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922464567 304 EDTDNWKWFIQrvksdlDLKN---GEGFTLISDKQKGLIKAVEEELPHIEHRTCARHIYGNIKKLHPNK--PRFKNLFWA 378
Cdd:COG3328  207 ESAAFWLEVLR------DLKNrglKDVLLVVSDGLKGLPEAIEAVFPGARWQRCIVHKIRNSLKYVPKKdrKAVAADLKA 280

                         90       100
                 ....*....|....*....|...
gi 922464567 379 VansFNEGDYKAALKELKAFDSQ 401
Cdd:COG3328  281 I---YQAPTKEAAEAALDAFAEK 300
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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