NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|767968137|ref|XP_011543317|]
View 

dnaJ homolog subfamily B member 13 isoform X7 [Homo sapiens]

Protein Classification

J domain-containing protein( domain architecture ID 10180526)

J domain-containing protein similar to the N-terminal conserved domain (called J domain) of DnaJ-like proteins, which is involved in regulating the ATPase activity of heat shock protein 70 (Hsp70) by ATP hydrolysis

Gene Ontology:  GO:0006457
PubMed:  9585179|23894646|15170475

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DnaJ_C cd10747
C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 ...
 35-161 6.80e-38

C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 protein mediates oligomerization and binding to denatured polypeptide substrate. DnaJ/Hsp40 is a widely conserved heat-shock protein. It prevents the aggregation of unfolded substrate and forms a ternary complex with both substrate and DnaK/Hsp70; the N-terminal J-domain of DnaJ/Hsp40 stimulates the ATPase activity of DnaK/Hsp70.


:

Pssm-ID: 199909 [Multi-domain]  Cd Length: 158  Bit Score: 127.54  E-value: 6.80e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  35 KDKILTIDVKPGWRQGTRITFEKEGDQGPN-IIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTlDD 113
Cdd:cd10747   33 EKKTLTVKIPAGVDDGQRLRLRGEGDAGPNgGPPGDLYVVIRVKPHPVFRRDGNDLYCEVPISLTEALLGGEIEVPT-LG 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 767968137 114 RLLNIPINDIIHPKYFKKVPGEGMPLPeDPTKKGDLFIFFDIQFPTRL 161
Cdd:cd10747  112 GKVKLKIPPGTQPGTVLRLKGKGMPRL-RGGGRGDLYVEVKVEFPKKL 158
 
Name Accession Description Interval E-value
DnaJ_C cd10747
C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 ...
 35-161 6.80e-38

C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 protein mediates oligomerization and binding to denatured polypeptide substrate. DnaJ/Hsp40 is a widely conserved heat-shock protein. It prevents the aggregation of unfolded substrate and forms a ternary complex with both substrate and DnaK/Hsp70; the N-terminal J-domain of DnaJ/Hsp40 stimulates the ATPase activity of DnaK/Hsp70.


Pssm-ID: 199909 [Multi-domain]  Cd Length: 158  Bit Score: 127.54  E-value: 6.80e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  35 KDKILTIDVKPGWRQGTRITFEKEGDQGPN-IIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTlDD 113
Cdd:cd10747   33 EKKTLTVKIPAGVDDGQRLRLRGEGDAGPNgGPPGDLYVVIRVKPHPVFRRDGNDLYCEVPISLTEALLGGEIEVPT-LG 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 767968137 114 RLLNIPINDIIHPKYFKKVPGEGMPLPeDPTKKGDLFIFFDIQFPTRL 161
Cdd:cd10747  112 GKVKLKIPPGTQPGTVLRLKGKGMPRL-RGGGRGDLYVEVKVEFPKKL 158
DnaJ_C pfam01556
DnaJ C terminal domain; This family consists of the C terminal region of the DnaJ protein. It ...
 33-158 2.07e-36

DnaJ C terminal domain; This family consists of the C terminal region of the DnaJ protein. It is always found associated with pfam00226 and pfam00684. DnaJ is a chaperone associated with the Hsp70 heat-shock system involved in protein folding and renaturation after stress. The two C-terminal domains CTDI and CTDII, both incorporated in this family are necessary for maintaining the J-domains in their specific relative positions. Structural analysis of PDB:1nlt shows that PF00684 is nested within this DnaJ C-terminal region.


Pssm-ID: 460251 [Multi-domain]  Cd Length: 213  Bit Score: 125.44  E-value: 2.07e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137   33 TIKDKILTIDVKPGWRQGTRITFEKEGDQGPN-IIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTL 111
Cdd:pfam01556  89 VVEKKTLEVKIPAGVDDGQRIRLRGEGDAGENgGPPGDLYVVIRVKPHPVFRRDGDDLYCTVPISLTEALLGGTIEVPTL 168

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 767968137  112 DDRL-LNIPINdiIHPKYFKKVPGEGMPLPeDPTKKGDLFIFFDIQFP 158
Cdd:pfam01556 169 DGKVkLKIPAG--TQPGTVLRLKGKGMPRL-KGGGRGDLYVTVKVEVP 213
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 37-170 1.94e-32

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 119.54  E-value: 1.94e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  37 KILTIDVKPGWRQGTRITFEKEGDQGPNIIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDDR-- 114
Cdd:PTZ00037 224 KILEVNIDKGVPNQHKITFHGEADEKPNEIPGNVVFILNEKPHDTFKREGGDLFITKKISLYEALTGFVFYITHLDGRkl 303

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767968137 115 LLNIPINDIIHPKYFKKVPGEGMPLPEDPTKKGDLFIFFDIQFPT--RLTPQKKQMLR 170
Cdd:PTZ00037 304 LVNTPPGEVVKPGDIKVINNEGMPTYKSPFKKGNLYVTFEVIFPVdrKFTNEEKEILK 361
 
Name Accession Description Interval E-value
DnaJ_C cd10747
C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 ...
 35-161 6.80e-38

C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 protein mediates oligomerization and binding to denatured polypeptide substrate. DnaJ/Hsp40 is a widely conserved heat-shock protein. It prevents the aggregation of unfolded substrate and forms a ternary complex with both substrate and DnaK/Hsp70; the N-terminal J-domain of DnaJ/Hsp40 stimulates the ATPase activity of DnaK/Hsp70.


Pssm-ID: 199909 [Multi-domain]  Cd Length: 158  Bit Score: 127.54  E-value: 6.80e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  35 KDKILTIDVKPGWRQGTRITFEKEGDQGPN-IIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTlDD 113
Cdd:cd10747   33 EKKTLTVKIPAGVDDGQRLRLRGEGDAGPNgGPPGDLYVVIRVKPHPVFRRDGNDLYCEVPISLTEALLGGEIEVPT-LG 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 767968137 114 RLLNIPINDIIHPKYFKKVPGEGMPLPeDPTKKGDLFIFFDIQFPTRL 161
Cdd:cd10747  112 GKVKLKIPPGTQPGTVLRLKGKGMPRL-RGGGRGDLYVEVKVEFPKKL 158
DnaJ_C pfam01556
DnaJ C terminal domain; This family consists of the C terminal region of the DnaJ protein. It ...
 33-158 2.07e-36

DnaJ C terminal domain; This family consists of the C terminal region of the DnaJ protein. It is always found associated with pfam00226 and pfam00684. DnaJ is a chaperone associated with the Hsp70 heat-shock system involved in protein folding and renaturation after stress. The two C-terminal domains CTDI and CTDII, both incorporated in this family are necessary for maintaining the J-domains in their specific relative positions. Structural analysis of PDB:1nlt shows that PF00684 is nested within this DnaJ C-terminal region.


Pssm-ID: 460251 [Multi-domain]  Cd Length: 213  Bit Score: 125.44  E-value: 2.07e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137   33 TIKDKILTIDVKPGWRQGTRITFEKEGDQGPN-IIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTL 111
Cdd:pfam01556  89 VVEKKTLEVKIPAGVDDGQRIRLRGEGDAGENgGPPGDLYVVIRVKPHPVFRRDGDDLYCTVPISLTEALLGGTIEVPTL 168

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 767968137  112 DDRL-LNIPINdiIHPKYFKKVPGEGMPLPeDPTKKGDLFIFFDIQFP 158
Cdd:pfam01556 169 DGKVkLKIPAG--TQPGTVLRLKGKGMPRL-KGGGRGDLYVTVKVEVP 213
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 37-170 1.94e-32

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 119.54  E-value: 1.94e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  37 KILTIDVKPGWRQGTRITFEKEGDQGPNIIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDDR-- 114
Cdd:PTZ00037 224 KILEVNIDKGVPNQHKITFHGEADEKPNEIPGNVVFILNEKPHDTFKREGGDLFITKKISLYEALTGFVFYITHLDGRkl 303

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767968137 115 LLNIPINDIIHPKYFKKVPGEGMPLPEDPTKKGDLFIFFDIQFPT--RLTPQKKQMLR 170
Cdd:PTZ00037 304 LVNTPPGEVVKPGDIKVINNEGMPTYKSPFKKGNLYVTFEVIFPVdrKFTNEEKEILK 361
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 29-171 1.01e-14

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 70.40  E-value: 1.01e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  29 GYSSTIKDKILTIDVKPGWRQGTRITFEKEGDQGPNIIPADIIFIVKE-KLHPRFRRENDNLFFVNPIPLGKALTCCTVE 107
Cdd:PRK14286 211 GQGLQEKRRTINIKIPPGVETGSRLKVSGEGEAGPNGGPHGDLYVVTHiKKHELFERQGNDLILVRKISLAQAILGAEIE 290

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767968137 108 VRTLDDRLLNIPINDIIHPKYFKKVPGEGMPLpEDPTKKGDLFIFFDIQFPTRLTPQKKQMLRQ 171
Cdd:PRK14286 291 VPTIDGKKAKMKIPEGTESGQVFRLKGHGMPY-LGAYGKGDQHVIVKIEIPKKITRRQRELIEE 353
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 33-171 1.70e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 66.50  E-value: 1.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  33 TIKDKILTIDVKPGWRQGTRITFEKEGDQGpniipADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLD 112
Cdd:PRK14299 152 EVAGERLSVRIPPGVREGQVIRLAGKGRQG-----GDLYLVVRLLPHPVFRLEGDDLYATVDVPAPIAVVGGKVRVMTLD 226

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137 113 DRL-LNIPIndiiHPKYFKKVPGEGMPLPEDPTKKGDLFIFFDIQFPTRLTPQKKQMLRQ 171
Cdd:PRK14299 227 GPVeVTIPP----RTQAGRKLRLKGKGWPRGPAGRGDQYAEVRITIPTRPTPEEERLYKQ 282
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 39-171 1.72e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 67.00  E-value: 1.72e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  39 LTIDVKPGWRQGTRITFEKEGDQGPNIIPADIIFI-VKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDDRLLN 117
Cdd:PRK14278 214 ITVKIPAGVGDGMRIRLAAQGEVGPGGGPAGDLYVeVHEQPHDVFVRDGDDLHCTVSVPMVDAALGTTVTVEAILDGPSE 293

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 767968137 118 IPINDIIHPKYFKKVPGEGMPLPEDpTKKGDLFIFFDIQFPTRLTPQKKQMLRQ 171
Cdd:PRK14278 294 ITIPPGTQPGSVITLRGRGMPHLRS-GGRGDLHAHVEVVVPTRLDHEDIELLRE 346
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 35-171 6.00e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 65.62  E-value: 6.00e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  35 KDKILTIDVKPGWRQGTRITFEKEGDQG-PNIIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDD 113
Cdd:PRK14283 217 ETKTISVKIPAGVETGSRLRVSGEGEMGdRGGEPGDLYVVIKVKPHKIFRREGANLYYEKPISFVQAALGDTVDVPTIDG 296

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 767968137 114 RL-LNIPINDIIHPKYfkKVPGEGMPLPEDPTkKGDLFIFFDIQFPTRLTPQKKQMLRQ 171
Cdd:PRK14283 297 PVeLKIPAGTQSGTTF--RLKGHGMPSLRWSG-KGNLYVKVKVVVPKKLSPKQKELLRE 352
PRK14293 PRK14293
molecular chaperone DnaJ;
37-171 1.43e-12

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 64.24  E-value: 1.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  37 KILTIDVKPGWRQGTRITFEKEGDQGPNIIPA-DIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLD-DR 114
Cdd:PRK14293 216 KKLKINIPAGVDTGTRLRVSGEGDAGLRGGPPgDLYVYLFVKNDPEFRRDGINILSEIKISYLQAILGDTLEVDTVDgPV 295

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767968137 115 LLNIPINdiIHPKYFKKVPGEGMPLPEDPTKKGDLFIFFDIQFPTRLTPQKKQMLRQ 171
Cdd:PRK14293 296 ELTIPAG--TQPNTVLTLENKGVPRLGNPVARGDHLITVKVKIPTRISDEERELLEK 350
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 35-171 7.45e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 62.56  E-value: 7.45e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  35 KDKILTIDVKPGWRQGTRITFEKEGDQG-PNIIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDD 113
Cdd:PRK14298 212 KTRKITVNVPAGADSGLRLKLSGEGEAGsPGAPSGDLYIVLHVKEHDYFERVGDDIISEIPISFTQAALGADIMVPTLYG 291

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 767968137 114 RL-LNIPINDIIHPKYfkKVPGEGMPLPEDpTKKGDLFIFFDIQFPTRLTPQKKQMLRQ 171
Cdd:PRK14298 292 KVkMNIPPGTQTHSVF--RLKDKGMPRLHG-HGKGDQLVKVIVKTPTKLTQEQKELLRE 347
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 29-158 9.36e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 62.09  E-value: 9.36e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  29 GYSSTIKDKILTIDVKPGWRQGTRITFEKEGDQGPNI-IPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVE 107
Cdd:PRK14291 216 GRGLVIKKETIKVRIPPGVDNGSKLRVPGKGHAGRFGgPPGDLYIIVKVKPHPLFERRGDNLYLDVNITVAEAVLGTELE 295

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767968137 108 VRTLDDRLLNIPINDIIHPKYFKKVPGEGMPLPEDpTKKGDLFIFFDIQFP 158
Cdd:PRK14291 296 VPLLDGKKEKVKIPPGTKEGDKIRVPGKGMPRLKG-SGYGDLVVRVHIDVP 345
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 29-171 1.94e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 58.21  E-value: 1.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  29 GYSSTIKDKILTIDVKPGWRQGTRITFEKEGDQGPNIIPA-DIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVE 107
Cdd:PRK14301 205 GSGIVQQTRELKVRIPAGVDTGSRLRLRGEGEPGVHGGPPgDLYVVITVEDDKIFQRQGQDLVVTQEISFVQAALGDRIE 284

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767968137 108 VRTLDDRL-LNIPiNDIIHPKYFkKVPGEGMPLPeDPTKKGDLFIFFDIQFPTRLTPQKKQMLRQ 171
Cdd:PRK14301 285 VPTLDDPVtLDIP-KGTQSGEVF-RLRGKGLPYL-GSSQKGDLLVEVSVVTPTKLTKRQEELLRE 346
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 29-169 4.29e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 57.21  E-value: 4.29e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  29 GYSSTIKDKILTIDVKPGWRQGTRITFEKEGDQGPNIiPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEV 108
Cdd:PRK14292 205 GRGRTLKAETVKVKLPRGIDEGYRIRVAGMGNEGPGG-NGDLYVHIEMEPHPELRREQEHLIYEARIGFAKAALGGQITV 283

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767968137 109 RTLDDRLLnIPINDIIHPKYFKKVPGEGMPLPEDpTKKGDLFIFFDIQFPTRLTPQKKQML 169
Cdd:PRK14292 284 PTLDGPQV-IEVKPGTQHGDLHRLRGQGMPRLQG-AGTGDLIVEYEIAVPKQLSPEAREAL 342
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 35-171 8.41e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 56.35  E-value: 8.41e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  35 KDKILTIDVKPGWRQGTRITFEKEGDQG----PNiipADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRT 110
Cdd:PRK14277 226 RRRKIKVNIPAGIDDGQMITLRGEGEPGikggPN---GDLYIVIKVKPHPLFKREGYNVYLEMPITFTDAALGGEIEIPT 302

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767968137 111 LDDRL-LNIPINDIIHPKYfkKVPGEGMPLPEDpTKKGDLFIFFDIQFPTRLTPQKKQMLRQ 171
Cdd:PRK14277 303 LDGKVkFTIPEGTQTGTKF--RLRGKGIPHLRG-RGRGDQIVKVYIEVPKKLTEKQKELLRE 361
PRK14289 PRK14289
molecular chaperone DnaJ;
34-169 2.77e-09

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 54.84  E-value: 2.77e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  34 IKDKILTIDVKPGWRQGTRITFEKEGDQGP-NIIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLD 112
Cdd:PRK14289 224 YGEEVITVKIPAGVAEGMQLSMNGKGNAGKhGGVNGDLLVVIEEEPHPELIRDENDLIYNLLLSVPTAALGGAVEVPTID 303

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767968137 113 DRlLNIPINDIIHPKYFKKVPGEGMPlPEDPTKKGDLFIFFDIQFPTRLTPQKKQML 169
Cdd:PRK14289 304 GK-AKVKIEAGTQPGKVLRLRNKGLP-SVNGYGTGDLLVNVSVYIPETLSKEEKQTL 358
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 5-171 3.23e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 54.77  E-value: 3.23e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137   5 SSEFFLLGFTRPYSQDFIRVL-----NEDGYSSTIKDKILTIDVKPGWRQGTRITFEKEGDQGPNIIPA-DIIFIVKEKL 78
Cdd:PRK14294 176 SQGFFSIRTTCPRCRGMGKVIvspckTCHGQGRVRVSKTVQVKIPAGVDTGSRLRLRGEGEAGVRGGPPgDLYVFLTVEP 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  79 HPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLD-DRLLNIPINdiIHPKYFKKVPGEGMP-LPEDptKKGDLFIFFDIQ 156
Cdd:PRK14294 256 HEFFERDGNDVHCKVPISFVQAALGAQIEVPTLEgERELKIPKG--TQPGDIFRFKGKGIPsLRGG--GRGDQIIEVEVK 331

                        170
                 ....*....|....*
gi 767968137 157 FPTRLTPQKKQMLRQ 171
Cdd:PRK14294 332 VPTRLTKKQEELLTE 346
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 28-171 2.64e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 49.16  E-value: 2.64e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  28 DGYSSTIKDKILTIDVKPGWRQGTRITFEKEGdQGPNIIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVE 107
Cdd:PRK14290 212 NGTGTVVVNEDISVKIPKGATDNLRLRVKGKG-QSYGGRTGDLYVVLRVNNDPNIQRINDDLYVDQKINFPQAALGGEIE 290

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767968137 108 VRTLDDRLlNIPINDIIHPKYFKKVPGEGMPlPEDPTKKGDLFIFFDIQFPTRLTPQKKQMLRQ 171
Cdd:PRK14290 291 IKLFREKY-NLKIPEGTQPGEVLKIKGAGMP-HLNGHGSGDLLVRINVEVPKRLTSKQKELIRE 352
PRK14295 PRK14295
molecular chaperone DnaJ;
40-169 6.12e-07

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 48.31  E-value: 6.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968137  40 TIDVK--PGWRQGTRITFEKEGDQGPNIIPA-DIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDDRLL 116
Cdd:PRK14295 236 TMQVRipAGVSDGQRIRLRGKGAPGERGGPAgDLYVVVHVDPHPVFGRSGDNLTVTVPVTFPEAALGAEVRVPTLGGPPV 315

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 767968137 117 NIPINDIIHPKYFKKVPGEGMPlPEDPTkKGDLFIFFDIQFPTRLTPQKKQML 169
Cdd:PRK14295 316 TVKLPPGTPNGRVLRVRGKGAV-RKDGT-RGDLLVTVEVAVPKDLSGKAREAL 366
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH