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Conserved domains on  [gi|767905182|ref|XP_011540102|]
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type-1 angiotensin II receptor-associated protein isoform X1 [Homo sapiens]

Protein Classification

AGTRAP domain-containing protein( domain architecture ID 10533969)

AGTRAP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AGTRAP pfam06396
Angiotensin II, type I receptor-associated protein (AGTRAP); This family consists of several ...
 22-166 3.16e-91

Angiotensin II, type I receptor-associated protein (AGTRAP); This family consists of several angiotensin II, type I receptor-associated protein (AGTRAP) sequences. AGTRAP is known to interact specifically with the carboxyl-terminal cytoplasmic region of the angiotensin II type 1 (AT(1)) receptor to regulate different aspects of AT(1) receptor physiology. The function of this family is unclear.


:

Pssm-ID: 461896  Cd Length: 148  Bit Score: 262.31  E-value: 3.16e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767905182   22 VILLGHWLLTTWGCIV--FSGSYAWANFTILALGVWAVAQRDSIDAISMFLGGLLATIFLDIVHISIFYPRVSLTDTGRF 99
Cdd:pfam06396   2 AIVLVHWLLTTWGCLGswLPGAYAWANFTVLAVGVWAIAQRDSIDAISMFLIGLLATILTDIIHIGIYYPRDILSDTNRF 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767905182  100 GVGMAILSLLLKPLSCCFVYHMYRERGGELLVHTGFLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQ 166
Cdd:pfam06396  82 SAGMAILSLLLKPVSCFFVYRMYRERGGELQVNSGFLGPSSDRSAYQTIDSPDQPADPTNSPPGRNV 148
 
Name Accession Description Interval E-value
AGTRAP pfam06396
Angiotensin II, type I receptor-associated protein (AGTRAP); This family consists of several ...
 22-166 3.16e-91

Angiotensin II, type I receptor-associated protein (AGTRAP); This family consists of several angiotensin II, type I receptor-associated protein (AGTRAP) sequences. AGTRAP is known to interact specifically with the carboxyl-terminal cytoplasmic region of the angiotensin II type 1 (AT(1)) receptor to regulate different aspects of AT(1) receptor physiology. The function of this family is unclear.


Pssm-ID: 461896  Cd Length: 148  Bit Score: 262.31  E-value: 3.16e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767905182   22 VILLGHWLLTTWGCIV--FSGSYAWANFTILALGVWAVAQRDSIDAISMFLGGLLATIFLDIVHISIFYPRVSLTDTGRF 99
Cdd:pfam06396   2 AIVLVHWLLTTWGCLGswLPGAYAWANFTVLAVGVWAIAQRDSIDAISMFLIGLLATILTDIIHIGIYYPRDILSDTNRF 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767905182  100 GVGMAILSLLLKPLSCCFVYHMYRERGGELLVHTGFLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQ 166
Cdd:pfam06396  82 SAGMAILSLLLKPVSCFFVYRMYRERGGELQVNSGFLGPSSDRSAYQTIDSPDQPADPTNSPPGRNV 148
AGTRAP smart00805
Angiotensin II, type I receptor-associated protein; This family consists of several ...
 1-171 6.92e-86

Angiotensin II, type I receptor-associated protein; This family consists of several angiotensin II, type I receptor-associated protein (AGTRAP) sequences. AGTRAP is known to interact specifically with the C-terminal cytoplasmic region of the angiotensin II type 1 (AT(1)) receptor to regulate different aspects of AT(1) receptor physiology. The function of this family is unclear.


Pssm-ID: 197883  Cd Length: 159  Bit Score: 249.01  E-value: 6.92e-86
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767905182     1 MELPAVNLKcasssvprnhphVILLGHWLLTTWGCIV--FSGSYAWANFTILALGVWAVAQRDSIDAISMFLGGLLATIF 78
Cdd:smart00805   1 MELPAVNLK------------VILFVHWLLTTWACLVswFSGAYAWANFTILALGVWAVAQRDSIDAIQMFLGGLLATIF 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767905182    79 LDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYHMYRERGGELLVHTGFLGSSQDRSAYQTIDsaeAPADPF 158
Cdd:smart00805  69 LDIVSISLFFTEVPLGDTGRFGVGMAILSLLLKPLSCCLVYHMYRERGGELPVNTGFVGPSQDRSSYQTID---APADPF 145

                          170
                   ....*....|....
gi 767905182   159 AVPEGRSQD-ARGY 171
Cdd:smart00805 146 ATNENKGPNvARGY 159
 
Name Accession Description Interval E-value
AGTRAP pfam06396
Angiotensin II, type I receptor-associated protein (AGTRAP); This family consists of several ...
 22-166 3.16e-91

Angiotensin II, type I receptor-associated protein (AGTRAP); This family consists of several angiotensin II, type I receptor-associated protein (AGTRAP) sequences. AGTRAP is known to interact specifically with the carboxyl-terminal cytoplasmic region of the angiotensin II type 1 (AT(1)) receptor to regulate different aspects of AT(1) receptor physiology. The function of this family is unclear.


Pssm-ID: 461896  Cd Length: 148  Bit Score: 262.31  E-value: 3.16e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767905182   22 VILLGHWLLTTWGCIV--FSGSYAWANFTILALGVWAVAQRDSIDAISMFLGGLLATIFLDIVHISIFYPRVSLTDTGRF 99
Cdd:pfam06396   2 AIVLVHWLLTTWGCLGswLPGAYAWANFTVLAVGVWAIAQRDSIDAISMFLIGLLATILTDIIHIGIYYPRDILSDTNRF 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767905182  100 GVGMAILSLLLKPLSCCFVYHMYRERGGELLVHTGFLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQ 166
Cdd:pfam06396  82 SAGMAILSLLLKPVSCFFVYRMYRERGGELQVNSGFLGPSSDRSAYQTIDSPDQPADPTNSPPGRNV 148
AGTRAP smart00805
Angiotensin II, type I receptor-associated protein; This family consists of several ...
 1-171 6.92e-86

Angiotensin II, type I receptor-associated protein; This family consists of several angiotensin II, type I receptor-associated protein (AGTRAP) sequences. AGTRAP is known to interact specifically with the C-terminal cytoplasmic region of the angiotensin II type 1 (AT(1)) receptor to regulate different aspects of AT(1) receptor physiology. The function of this family is unclear.


Pssm-ID: 197883  Cd Length: 159  Bit Score: 249.01  E-value: 6.92e-86
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767905182     1 MELPAVNLKcasssvprnhphVILLGHWLLTTWGCIV--FSGSYAWANFTILALGVWAVAQRDSIDAISMFLGGLLATIF 78
Cdd:smart00805   1 MELPAVNLK------------VILFVHWLLTTWACLVswFSGAYAWANFTILALGVWAVAQRDSIDAIQMFLGGLLATIF 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767905182    79 LDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYHMYRERGGELLVHTGFLGSSQDRSAYQTIDsaeAPADPF 158
Cdd:smart00805  69 LDIVSISLFFTEVPLGDTGRFGVGMAILSLLLKPLSCCLVYHMYRERGGELPVNTGFVGPSQDRSSYQTID---APADPF 145

                          170
                   ....*....|....
gi 767905182   159 AVPEGRSQD-ARGY 171
Cdd:smart00805 146 ATNENKGPNvARGY 159
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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