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Conserved domains on  [gi|767943731|ref|XP_011534493|]
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fibronectin type III domain-containing protein 1 isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
1541-1632 2.88e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.44  E-value: 2.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1541 APRNITVVAVEgcHSFVIVDWDK-ATPGDVVTGYLVYsasYEDFIRNKW---STQASSVTHLPIENLKPNTRYYFKVQAQ 1616
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPpEDDGGPITGYVVE---YREKGSGDWkevEVTPGSETSYTLTGLKPGTEYEFRVRAV 77
                          90
                  ....*....|....*.
gi 767943731 1617 NPHGYGPISPSVSFVT 1632
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
245-335 5.58e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 63.28  E-value: 5.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  245 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 324
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80
                          90
                  ....*....|.
gi 767943731  325 GLGPHSKAFIV 335
Cdd:cd00063    81 GESPPSESVTV 91
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
515-947 3.27e-11

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 68.66  E-value: 3.27e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  515 RPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQPR----PALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAe 590
Cdd:PHA03307   31 AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP- 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  591 eDSSASAPPSRLSPPHGGSSrllPTQPHLSSPLSKGGKDGEDAPATNSNAPsrstmsssvsshlssrtqVSEGAEASDGE 670
Cdd:PHA03307  110 -GPSSPDPPPPTPPPASPPP---SPAPDLSEMLRPVGSPGPPPAASPPAAG------------------ASPAAVASDAA 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  671 SHGDGdredgGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHpRVPSHSDS 750
Cdd:PHA03307  168 SSRQA-----ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAG-ASSSDSSS 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  751 HPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPqgkySSLAS 830
Cdd:PHA03307  242 SESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP----RASSS 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  831 KAQDVQQSTDADTEGHSPKAQPGStdrhaSPARPPA-ARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGR 909
Cdd:PHA03307  318 SSSSRESSSSSTSSSSESSRGAAV-----SPGPSPSrSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 767943731  910 SPSQPRL-----SLTQAGRPRPTSQGRSHSSSDPYTASSRGML 947
Cdd:PHA03307  393 AVAGRARrrdatGRFPAGRPRPSPLDAGAASGAFYARYPLLTP 435
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
144-237 1.84e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 56.35  E-value: 1.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  144 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGE--LARWDYKQIANRRVLIENLIPDTVYEFAVRIS 221
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSW-TPPEDDGGPIT---GYVVEYREKGSgdWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77
                          90
                  ....*....|....*.
gi 767943731  222 QGERDGKWSTSVFQRT 237
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
PHA03247 super family cl33720
large tegument protein UL36; Provisional
694-1235 4.76e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.88  E-value: 4.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  694 RPASGHFhllrhkPFAANG-RSPsrfsiGRGPRLQPSSSPQSTVPSRA-HPRVPSHSDSHPKLSSGIHGDEE---DEKPL 768
Cdd:PHA03247 2482 RPAEARF------PFAAGAaPDP-----GGGGPPDPDAPPAPSRLAPAiLPDEPVGEPVHPRMLTWIRGLEElasDDAGD 2550
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  769 PATVVNDHVPSSSrqpisrgwedlrrsPQRGASLHRKEPIPENPKSTGADTHPqgkysslaskaqdvqqstDADTEGHSP 848
Cdd:PHA03247 2551 PPPPLPPAAPPAA--------------PDRSVPPPRPAPRPSEPAVTSRARRP------------------DAPPQSARP 2598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  849 KAQPGSTDRHASPARPPAARSQQHPsvPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAgrsPSQPRLSLTQagrpRPTS 928
Cdd:PHA03247 2599 RAPVDDRGDPRGPAPPSPLPPDTHA--PDPPPPSPSPAANEPDPHPPPTVPPPERPRDD---PAPGRVSRPR----RARR 2669
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  929 QGRSHSSSDPYTASSRGMLPTALQN----QDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGA 1004
Cdd:PHA03247 2670 LGRAAQASSPPQRPRRRAARPTVGSltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1005 GGDHRSQRGHAASPARPSRPGGPQSRARVPSRAAPgksePPSKRPLSSkSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVP 1084
Cdd:PHA03247 2750 TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASP 2824
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1085 KwPSSSTPRGGKDADGSLAKEEREPAIALaprGGSLAP---VKRPLPPPPGSSPRAShvPSRLPPRSAATVSPVAGTHPW 1161
Cdd:PHA03247 2825 A-GPLPPPTSAQPTAPPPPPGPPPPSLPL---GGSVAPggdVRRRPPSRSPAAKPAA--PARPPVRRLARPAVSRSTESF 2898
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767943731 1162 PQyttraPPGHFSTTPMLSLRQRMMharfRNPLSRQPARPSYRQGYNGRPNVEGKVLPGSNGKPNGQRIINGPQ 1235
Cdd:PHA03247 2899 AL-----PPDQPERPPQPQAPPPPQ----PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
41-127 3.48e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 3.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731   41 PNKPLRVRVRS-SDDRLSVAWKAPRLSGAksprRSRGFLLGYGESGRK--MNYVPLTRDERTHEIKKLASESVYVVSLQS 117
Cdd:cd00063     1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGG----PITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRA 76
                          90
                  ....*....|
gi 767943731  118 MNSQGRSQPV 127
Cdd:cd00063    77 VNGGGESPPS 86
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
1541-1632 2.88e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.44  E-value: 2.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1541 APRNITVVAVEgcHSFVIVDWDK-ATPGDVVTGYLVYsasYEDFIRNKW---STQASSVTHLPIENLKPNTRYYFKVQAQ 1616
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPpEDDGGPITGYVVE---YREKGSGDWkevEVTPGSETSYTLTGLKPGTEYEFRVRAV 77
                          90
                  ....*....|....*.
gi 767943731 1617 NPHGYGPISPSVSFVT 1632
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
245-335 5.58e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 63.28  E-value: 5.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  245 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 324
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80
                          90
                  ....*....|.
gi 767943731  325 GLGPHSKAFIV 335
Cdd:cd00063    81 GESPPSESVTV 91
fn3 pfam00041
Fibronectin type III domain;
245-330 7.47e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 7.47e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731   245 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 324
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

                   ....*.
gi 767943731   325 GLGPHS 330
Cdd:pfam00041   80 GEGPPS 85
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
515-947 3.27e-11

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 68.66  E-value: 3.27e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  515 RPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQPR----PALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAe 590
Cdd:PHA03307   31 AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP- 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  591 eDSSASAPPSRLSPPHGGSSrllPTQPHLSSPLSKGGKDGEDAPATNSNAPsrstmsssvsshlssrtqVSEGAEASDGE 670
Cdd:PHA03307  110 -GPSSPDPPPPTPPPASPPP---SPAPDLSEMLRPVGSPGPPPAASPPAAG------------------ASPAAVASDAA 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  671 SHGDGdredgGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHpRVPSHSDS 750
Cdd:PHA03307  168 SSRQA-----ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAG-ASSSDSSS 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  751 HPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPqgkySSLAS 830
Cdd:PHA03307  242 SESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP----RASSS 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  831 KAQDVQQSTDADTEGHSPKAQPGStdrhaSPARPPA-ARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGR 909
Cdd:PHA03307  318 SSSSRESSSSSTSSSSESSRGAAV-----SPGPSPSrSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 767943731  910 SPSQPRL-----SLTQAGRPRPTSQGRSHSSSDPYTASSRGML 947
Cdd:PHA03307  393 AVAGRARrrdatGRFPAGRPRPSPLDAGAASGAFYARYPLLTP 435
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
144-237 1.84e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 56.35  E-value: 1.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  144 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGE--LARWDYKQIANRRVLIENLIPDTVYEFAVRIS 221
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSW-TPPEDDGGPIT---GYVVEYREKGSgdWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77
                          90
                  ....*....|....*.
gi 767943731  222 QGERDGKWSTSVFQRT 237
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
PHA03247 PHA03247
large tegument protein UL36; Provisional
694-1235 4.76e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.88  E-value: 4.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  694 RPASGHFhllrhkPFAANG-RSPsrfsiGRGPRLQPSSSPQSTVPSRA-HPRVPSHSDSHPKLSSGIHGDEE---DEKPL 768
Cdd:PHA03247 2482 RPAEARF------PFAAGAaPDP-----GGGGPPDPDAPPAPSRLAPAiLPDEPVGEPVHPRMLTWIRGLEElasDDAGD 2550
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  769 PATVVNDHVPSSSrqpisrgwedlrrsPQRGASLHRKEPIPENPKSTGADTHPqgkysslaskaqdvqqstDADTEGHSP 848
Cdd:PHA03247 2551 PPPPLPPAAPPAA--------------PDRSVPPPRPAPRPSEPAVTSRARRP------------------DAPPQSARP 2598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  849 KAQPGSTDRHASPARPPAARSQQHPsvPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAgrsPSQPRLSLTQagrpRPTS 928
Cdd:PHA03247 2599 RAPVDDRGDPRGPAPPSPLPPDTHA--PDPPPPSPSPAANEPDPHPPPTVPPPERPRDD---PAPGRVSRPR----RARR 2669
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  929 QGRSHSSSDPYTASSRGMLPTALQN----QDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGA 1004
Cdd:PHA03247 2670 LGRAAQASSPPQRPRRRAARPTVGSltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1005 GGDHRSQRGHAASPARPSRPGGPQSRARVPSRAAPgksePPSKRPLSSkSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVP 1084
Cdd:PHA03247 2750 TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASP 2824
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1085 KwPSSSTPRGGKDADGSLAKEEREPAIALaprGGSLAP---VKRPLPPPPGSSPRAShvPSRLPPRSAATVSPVAGTHPW 1161
Cdd:PHA03247 2825 A-GPLPPPTSAQPTAPPPPPGPPPPSLPL---GGSVAPggdVRRRPPSRSPAAKPAA--PARPPVRRLARPAVSRSTESF 2898
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767943731 1162 PQyttraPPGHFSTTPMLSLRQRMMharfRNPLSRQPARPSYRQGYNGRPNVEGKVLPGSNGKPNGQRIINGPQ 1235
Cdd:PHA03247 2899 AL-----PPDQPERPPQPQAPPPPQ----PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
1541-1622 4.11e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 52.23  E-value: 4.11e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731   1541 APRNITVVAVEGchSFVIVDWDKAtPGDVVTGYLV-YSASYEDfIRNKWSTQASSV--THLPIENLKPNTRYYFKVQAQN 1617
Cdd:smart00060    3 PPSNLRVTDVTS--TSVTLSWEPP-PDDGITGYIVgYRVEYRE-EGSEWKEVNVTPssTSYTLTGLKPGTEYEFRVRAVN 78

                    ....*
gi 767943731   1618 PHGYG 1622
Cdd:smart00060   79 GAGEG 83
fn3 pfam00041
Fibronectin type III domain;
1541-1625 3.99e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 49.34  E-value: 3.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  1541 APRNITVVAVEgcHSFVIVDWDKATPGD-VVTGYLVYSASYEDFIRNKWSTQASSVTHLPIENLKPNTRYYFKVQAQNPH 1619
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNgPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

                   ....*.
gi 767943731  1620 GYGPIS 1625
Cdd:pfam00041   80 GEGPPS 85
fn3 pfam00041
Fibronectin type III domain;
144-230 8.89e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 48.57  E-value: 8.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731   144 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGELARWDYKQIAN--RRVLIENLIPDTVYEFAVRIS 221
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSW-TPPPDGNGPIT---GYEVEYRPKNSGEPWNEITVPGttTSVTLTGLKPGTEYEVRVQAV 76

                   ....*....
gi 767943731   222 QGERDGKWS 230
Cdd:pfam00041   77 NGGGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
245-327 9.76e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 48.38  E-value: 9.76e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731    245 APENLNVWPVNgkPTVVAASWDALPETEGKvkEYILSYAPALKPFGA--KSLTYPGDTTSALVDGLQPGERYLFKIRATN 322
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGIT--GYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVN 78

                    ....*
gi 767943731    323 RRGLG 327
Cdd:smart00060   79 GAGEG 83
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
146-387 1.85e-06

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 52.70  E-value: 1.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  146 PDDISVRVMSSQSVLVSWvDPVLEKqkkvvASRQYTVrYREKGELARWdyKQIANRRVLI---ENLIPDTVYEFAVR--I 220
Cdd:COG3401   236 PTGLTATADTPGSVTLSW-DPVTES-----DATGYRV-YRSNSGDGPF--TKVATVTTTSytdTGLTNGTTYYYRVTavD 306
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  221 SQGERdGKWSTSVfQRTPESAPTTAPENLNVwpVNGKPTVVAASWDalPETEGKVKEYILSYAPAlKPFGAKSLTYPGDT 300
Cdd:COG3401   307 AAGNE-SAPSNVV-SVTTDLTPPAAPSGLTA--TAVGSSSITLSWT--ASSDADVTGYNVYRSTS-GGGTYTKIAETVTT 379
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  301 TSALVDGLQPGERYLFKIRATNRRGLGPHSKAFIVAMPTTskaDVEQNTEDNGKPEKPEPSSPSPRAPASSQHPSVPASP 380
Cdd:COG3401   380 TSYTDTGLTPGTTYYYKVTAVDAAGNESAPSEEVSATTAS---AASGESLTASVDAVPLTDVAGATAAASAASNPGVSAA 456

                  ....*..
gi 767943731  381 QGRNAKD 387
Cdd:COG3401   457 VLADGGD 463
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
146-219 1.16e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 45.30  E-value: 1.16e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767943731    146 PDDISVRVMSSQSVLVSWVDPVLEKQKKvvasrqYTVRYREKGELARWDYKQI----ANRRVLIENLIPDTVYEFAVR 219
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSWEPPPDDGITG------YIVGYRVEYREEGSEWKEVnvtpSSTSYTLTGLKPGTEYEFRVR 75
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
206-325 1.53e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 50.00  E-value: 1.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  206 ENLIPDTVYEFAVRISQGERDGKWSTSVFQRTPESAPtTAPENLNVwpVNGKPTVVAASWDalPETEGKVKEYILSYAPA 285
Cdd:COG3401   197 GDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTA--TADTPGSVTLSWD--PVTESDATGYRVYRSNS 271
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 767943731  286 lkpfGAKSLTYPGDT--TSALVDGLQPGERYLFKIRATNRRG 325
Cdd:COG3401   272 ----GDGPFTKVATVttTSYTDTGLTNGTTYYYRVTAVDAAG 309
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
41-127 3.48e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 3.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731   41 PNKPLRVRVRS-SDDRLSVAWKAPRLSGAksprRSRGFLLGYGESGRK--MNYVPLTRDERTHEIKKLASESVYVVSLQS 117
Cdd:cd00063     1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGG----PITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRA 76
                          90
                  ....*....|
gi 767943731  118 MNSQGRSQPV 127
Cdd:cd00063    77 VNGGGESPPS 86
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
1541-1632 2.88e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.44  E-value: 2.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1541 APRNITVVAVEgcHSFVIVDWDK-ATPGDVVTGYLVYsasYEDFIRNKW---STQASSVTHLPIENLKPNTRYYFKVQAQ 1616
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPpEDDGGPITGYVVE---YREKGSGDWkevEVTPGSETSYTLTGLKPGTEYEFRVRAV 77
                          90
                  ....*....|....*.
gi 767943731 1617 NPHGYGPISPSVSFVT 1632
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
245-335 5.58e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 63.28  E-value: 5.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  245 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 324
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80
                          90
                  ....*....|.
gi 767943731  325 GLGPHSKAFIV 335
Cdd:cd00063    81 GESPPSESVTV 91
fn3 pfam00041
Fibronectin type III domain;
245-330 7.47e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 7.47e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731   245 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 324
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

                   ....*.
gi 767943731   325 GLGPHS 330
Cdd:pfam00041   80 GEGPPS 85
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
515-947 3.27e-11

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 68.66  E-value: 3.27e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  515 RPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQPR----PALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAe 590
Cdd:PHA03307   31 AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP- 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  591 eDSSASAPPSRLSPPHGGSSrllPTQPHLSSPLSKGGKDGEDAPATNSNAPsrstmsssvsshlssrtqVSEGAEASDGE 670
Cdd:PHA03307  110 -GPSSPDPPPPTPPPASPPP---SPAPDLSEMLRPVGSPGPPPAASPPAAG------------------ASPAAVASDAA 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  671 SHGDGdredgGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHpRVPSHSDS 750
Cdd:PHA03307  168 SSRQA-----ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAG-ASSSDSSS 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  751 HPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPqgkySSLAS 830
Cdd:PHA03307  242 SESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP----RASSS 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  831 KAQDVQQSTDADTEGHSPKAQPGStdrhaSPARPPA-ARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGR 909
Cdd:PHA03307  318 SSSSRESSSSSTSSSSESSRGAAV-----SPGPSPSrSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 767943731  910 SPSQPRL-----SLTQAGRPRPTSQGRSHSSSDPYTASSRGML 947
Cdd:PHA03307  393 AVAGRARrrdatGRFPAGRPRPSPLDAGAASGAFYARYPLLTP 435
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
144-237 1.84e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 56.35  E-value: 1.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  144 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGE--LARWDYKQIANRRVLIENLIPDTVYEFAVRIS 221
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSW-TPPEDDGGPIT---GYVVEYREKGSgdWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77
                          90
                  ....*....|....*.
gi 767943731  222 QGERDGKWSTSVFQRT 237
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
PHA03247 PHA03247
large tegument protein UL36; Provisional
694-1235 4.76e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.88  E-value: 4.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  694 RPASGHFhllrhkPFAANG-RSPsrfsiGRGPRLQPSSSPQSTVPSRA-HPRVPSHSDSHPKLSSGIHGDEE---DEKPL 768
Cdd:PHA03247 2482 RPAEARF------PFAAGAaPDP-----GGGGPPDPDAPPAPSRLAPAiLPDEPVGEPVHPRMLTWIRGLEElasDDAGD 2550
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  769 PATVVNDHVPSSSrqpisrgwedlrrsPQRGASLHRKEPIPENPKSTGADTHPqgkysslaskaqdvqqstDADTEGHSP 848
Cdd:PHA03247 2551 PPPPLPPAAPPAA--------------PDRSVPPPRPAPRPSEPAVTSRARRP------------------DAPPQSARP 2598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  849 KAQPGSTDRHASPARPPAARSQQHPsvPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAgrsPSQPRLSLTQagrpRPTS 928
Cdd:PHA03247 2599 RAPVDDRGDPRGPAPPSPLPPDTHA--PDPPPPSPSPAANEPDPHPPPTVPPPERPRDD---PAPGRVSRPR----RARR 2669
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  929 QGRSHSSSDPYTASSRGMLPTALQN----QDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGA 1004
Cdd:PHA03247 2670 LGRAAQASSPPQRPRRRAARPTVGSltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1005 GGDHRSQRGHAASPARPSRPGGPQSRARVPSRAAPgksePPSKRPLSSkSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVP 1084
Cdd:PHA03247 2750 TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASP 2824
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1085 KwPSSSTPRGGKDADGSLAKEEREPAIALaprGGSLAP---VKRPLPPPPGSSPRAShvPSRLPPRSAATVSPVAGTHPW 1161
Cdd:PHA03247 2825 A-GPLPPPTSAQPTAPPPPPGPPPPSLPL---GGSVAPggdVRRRPPSRSPAAKPAA--PARPPVRRLARPAVSRSTESF 2898
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767943731 1162 PQyttraPPGHFSTTPMLSLRQRMMharfRNPLSRQPARPSYRQGYNGRPNVEGKVLPGSNGKPNGQRIINGPQ 1235
Cdd:PHA03247 2899 AL-----PPDQPERPPQPQAPPPPQ----PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
PHA03247 PHA03247
large tegument protein UL36; Provisional
360-1013 8.65e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 8.65e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  360 PSSPSPRAPASSQHPSVPAS---PQGRNAKDLLLDLKNKILANGGAPRKPQLRAKKAEELdlqsTEITGEEELGSRED-- 434
Cdd:PHA03247 2475 PGAPVYRRPAEARFPFAAGAapdPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRML----TWIRGLEELASDDAgd 2550
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  435 -----SPMSPSDTQDQKrtlRPPSRHGHSVVAPGRTAvRARMPALPRRegvdkpgfslATQPR-PGAPPSASASPAHHAS 508
Cdd:PHA03247 2551 pppplPPAAPPAAPDRS---VPPPRPAPRPSEPAVTS-RARRPDAPPQ----------SARPRaPVDDRGDPRGPAPPSP 2616
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  509 TQGTSHRPSLPASLNdndlvDSDEDERAVGSLHPKGAFAQPRPALSPSRQSPSSVLRDRS-SVHPGAKPASPARRTPHSG 587
Cdd:PHA03247 2617 LPPDTHAPDPPPPSP-----SPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGrAAQASSPPQRPRRRAARPT 2691
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  588 AAEEDSSASAPPsrlsPPHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMSSSvsshlssrTQVSEGAEAS 667
Cdd:PHA03247 2692 VGSLTSLADPPP----PPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA--------TPGGPARPAR 2759
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  668 DGESHGDGDREDGGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTV--PSRAHPRVP 745
Cdd:PHA03247 2760 PPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLppPTSAQPTAP 2839
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  746 SHSDSHPKLSSGIHGDEEDEKPL----PATVVNDHVPSSSRQPISR-GWEDLRRSPQrgaSLHRKEPIPENPKSTGADTH 820
Cdd:PHA03247 2840 PPPPGPPPPSLPLGGSVAPGGDVrrrpPSRSPAAKPAAPARPPVRRlARPAVSRSTE---SFALPPDQPERPPQPQAPPP 2916
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  821 PQgkysslaskaqdVQQSTDADTEGHSPKAQPGSTDRHASPARPPAARSQQHPSVPR----RMTPGRAPQQQPPPpvats 896
Cdd:PHA03247 2917 PQ------------PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQpwlgALVPGRVAVPRFRV----- 2979
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  897 qhhpgPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRS---HSSSDPYTASSRGMLPTALQNQDEDAQGSYDDDSTEVEAQD 973
Cdd:PHA03247 2980 -----PQPAPSREAPASSTPPLTGHSLSRVSSWASSlalHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEA 3054
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|
gi 767943731  974 VRApahaarAKEAAASLPKHQQVESPTGAGAGGDHRSQRG 1013
Cdd:PHA03247 3055 LDP------LPPEPHDPFAHEPDPATPEAGARESPSSQFG 3088
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
807-1236 1.02e-08

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 60.57  E-value: 1.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  807 PIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHSPKAQPGSTD-RHASPARPPAARSQQHPSVPRRMTPGRAP 885
Cdd:PHA03307   78 EAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPpSPAPDLSEMLRPVGSPGPPPAASPPAAGA 157
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  886 QQQPPPPVATSQHHP------GPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSrgmlPTALQNQDEDAQ 959
Cdd:PHA03307  158 SPAAVASDAASSRQAalplssPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPA----PAPGRSAADDAG 233
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  960 GSYDDDSTEVEAQDVRAPAHAARakeaaasLPKHQQVESPT--GAGAGGDHRSQRghaASPARPSrpGGPQSRARVPSRA 1037
Cdd:PHA03307  234 ASSSDSSSSESSGCGWGPENECP-------LPRPAPITLPTriWEASGWNGPSSR---PGPASSS--SSPRERSPSPSPS 301
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1038 APGKSEPPSKRPLSSKSQQSVSAEDDEEEDAGFfkggkedlLSSSVPKWPSSSTPRGGKDADGSlakeerepaialAPRG 1117
Cdd:PHA03307  302 SPGSGPAPSSPRASSSSSSSRESSSSSTSSSSE--------SSRGAAVSPGPSPSRSPSPSRPP------------PPAD 361
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1118 GSlaPVKRPLPPPPGSSPRASHVPSRLPPRSAATVSPvagthpwpqyttrappghfsttpmlslRQRMMHARFRNPLSRQ 1197
Cdd:PHA03307  362 PS--SPRKRPRPSRAPSSPAASAGRPTRRRARAAVAG---------------------------RARRRDATGRFPAGRP 412
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 767943731 1198 PARPSYRQGYNGRPNVE-------GKVLPGSNGKPNGqRIINGPQG 1236
Cdd:PHA03307  413 RPSPLDAGAASGAFYARyplltpsGEPWPGSPPPPPG-RVRYGGLG 457
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
1541-1622 4.11e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 52.23  E-value: 4.11e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731   1541 APRNITVVAVEGchSFVIVDWDKAtPGDVVTGYLV-YSASYEDfIRNKWSTQASSV--THLPIENLKPNTRYYFKVQAQN 1617
Cdd:smart00060    3 PPSNLRVTDVTS--TSVTLSWEPP-PDDGITGYIVgYRVEYRE-EGSEWKEVNVTPssTSYTLTGLKPGTEYEFRVRAVN 78

                    ....*
gi 767943731   1618 PHGYG 1622
Cdd:smart00060   79 GAGEG 83
fn3 pfam00041
Fibronectin type III domain;
1541-1625 3.99e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 49.34  E-value: 3.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  1541 APRNITVVAVEgcHSFVIVDWDKATPGD-VVTGYLVYSASYEDFIRNKWSTQASSVTHLPIENLKPNTRYYFKVQAQNPH 1619
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNgPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79

                   ....*.
gi 767943731  1620 GYGPIS 1625
Cdd:pfam00041   80 GEGPPS 85
fn3 pfam00041
Fibronectin type III domain;
144-230 8.89e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 48.57  E-value: 8.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731   144 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGELARWDYKQIAN--RRVLIENLIPDTVYEFAVRIS 221
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSW-TPPPDGNGPIT---GYEVEYRPKNSGEPWNEITVPGttTSVTLTGLKPGTEYEVRVQAV 76

                   ....*....
gi 767943731   222 QGERDGKWS 230
Cdd:pfam00041   77 NGGGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
245-327 9.76e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 48.38  E-value: 9.76e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731    245 APENLNVWPVNgkPTVVAASWDALPETEGKvkEYILSYAPALKPFGA--KSLTYPGDTTSALVDGLQPGERYLFKIRATN 322
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGIT--GYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVN 78

                    ....*
gi 767943731    323 RRGLG 327
Cdd:smart00060   79 GAGEG 83
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
146-387 1.85e-06

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 52.70  E-value: 1.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  146 PDDISVRVMSSQSVLVSWvDPVLEKqkkvvASRQYTVrYREKGELARWdyKQIANRRVLI---ENLIPDTVYEFAVR--I 220
Cdd:COG3401   236 PTGLTATADTPGSVTLSW-DPVTES-----DATGYRV-YRSNSGDGPF--TKVATVTTTSytdTGLTNGTTYYYRVTavD 306
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  221 SQGERdGKWSTSVfQRTPESAPTTAPENLNVwpVNGKPTVVAASWDalPETEGKVKEYILSYAPAlKPFGAKSLTYPGDT 300
Cdd:COG3401   307 AAGNE-SAPSNVV-SVTTDLTPPAAPSGLTA--TAVGSSSITLSWT--ASSDADVTGYNVYRSTS-GGGTYTKIAETVTT 379
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  301 TSALVDGLQPGERYLFKIRATNRRGLGPHSKAFIVAMPTTskaDVEQNTEDNGKPEKPEPSSPSPRAPASSQHPSVPASP 380
Cdd:COG3401   380 TSYTDTGLTPGTTYYYKVTAVDAAGNESAPSEEVSATTAS---AASGESLTASVDAVPLTDVAGATAAASAASNPGVSAA 456

                  ....*..
gi 767943731  381 QGRNAKD 387
Cdd:COG3401   457 VLADGGD 463
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
353-732 4.33e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 52.10  E-value: 4.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  353 GKPEKPEPSSPSPRAPassqhPSVPASPQGRNAKDLLLDLKnkilANGGAPRKPQLRAKKAEELDLQSTEITGEeelgSR 432
Cdd:PHA03307  104 GSPTPPGPSSPDPPPP-----TPPPASPPPSPAPDLSEMLR----PVGSPGPPPAASPPAAGASPAAVASDAAS----SR 170
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  433 EDSPMSPSdTQDQKRTLRPPSRHGHSVVAPGRTAVRARMPALPRREGVDKPGFSLATQPRPGAPPSASASPAHHASTQGT 512
Cdd:PHA03307  171 QAALPLSS-PEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGW 249
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  513 SHRPSLPASLNDNDLVDSDEDERAVGSLHPkgafaqPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEED 592
Cdd:PHA03307  250 GPENECPLPRPAPITLPTRIWEASGWNGPS------SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRE 323
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  593 SSASAPPSRLSPPHGGSSRllPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMSSSVSSHLSSRTQVSEGAEASDGesh 672
Cdd:PHA03307  324 SSSSSTSSSSESSRGAAVS--PGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRA--- 398
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  673 gdgdredggRQAEATAQTLRARPASGhfhllrhkPFAANGRSPSRFSigRGPRLQPSSSP 732
Cdd:PHA03307  399 ---------RRRDATGRFPAGRPRPS--------PLDAGAASGAFYA--RYPLLTPSGEP 439
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
146-219 1.16e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 45.30  E-value: 1.16e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767943731    146 PDDISVRVMSSQSVLVSWVDPVLEKQKKvvasrqYTVRYREKGELARWDYKQI----ANRRVLIENLIPDTVYEFAVR 219
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSWEPPPDDGITG------YIVGYRVEYREEGSEWKEVnvtpSSTSYTLTGLKPGTEYEFRVR 75
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1535-1637 1.51e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 50.00  E-value: 1.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1535 DLPPQHAPRNITVVAVEGchSFVIVDWDKATPGDVvTGYLVYSASYEDFIRNKWSTQASSVTHLpIENLKPNTRYYFKVQ 1614
Cdd:COG3401   323 DLTPPAAPSGLTATAVGS--SSITLSWTASSDADV-TGYNVYRSTSGGGTYTKIAETVTTTSYT-DTGLTPGTTYYYKVT 398
                          90       100
                  ....*....|....*....|....
gi 767943731 1615 AQNPHG-YGPISPSVSFVTESDNP 1637
Cdd:COG3401   399 AVDAAGnESAPSEEVSATTASAAS 422
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
206-325 1.53e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 50.00  E-value: 1.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  206 ENLIPDTVYEFAVRISQGERDGKWSTSVFQRTPESAPtTAPENLNVwpVNGKPTVVAASWDalPETEGKVKEYILSYAPA 285
Cdd:COG3401   197 GDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTA--TADTPGSVTLSWD--PVTESDATGYRVYRSNS 271
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 767943731  286 lkpfGAKSLTYPGDT--TSALVDGLQPGERYLFKIRATNRRG 325
Cdd:COG3401   272 ----GDGPFTKVATVttTSYTDTGLTNGTTYYYRVTAVDAAG 309
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
155-351 3.51e-05

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 48.79  E-value: 3.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  155 SSQSVLVSWVDPVlekqkkvVASRqYTVRYREKGElaRWDYKQIANRRVLIENLIPDTVYEFAVR-ISQGERDGKWSTSV 233
Cdd:COG4733   550 AVTTLTVSWDAPA-------GAVA-YEVEWRRDDG--NWVSVPRTSGTSFEVPGIYAGDYEVRVRaINALGVSSAWAASS 619
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  234 -FQRTPESAPTTAPENLNVWPVNGKptvVAASWDALPETEgkVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGE 312
Cdd:COG4733   620 eTTVTGKTAPPPAPTGLTATGGLGG---ITLSWSFPVDAD--TLRTEIRYSTTGDWASATVAQALYPGNTYTLAGLKAGQ 694
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767943731  313 RYLFKIRATNRRGLgpHSKAFIVAMPTTSKADVEQNTED 351
Cdd:COG4733   695 TYYYRARAVDRSGN--VSAWWVSGQASADAAGILDAITG 731
PHA03247 PHA03247
large tegument protein UL36; Provisional
724-1159 7.67e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 7.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  724 PRLQPSSSPQSTVPSRAHPRVP--------SHSDSHPKLSSG-IHGDEEDEKPLPAtvvndhvPSSSRQPISRGWEDLRR 794
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPAPRPSepavtsraRRPDAPPQSARPrAPVDDRGDPRGPA-------PPSPLPPDTHAPDPPPP 2629
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  795 SPQRGASLHRKEPIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDAD--TEGHSPKAQPGSTDRHASPARPPAARSQQH 872
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASspPQRPRRRAARPTVGSLTSLADPPPPPPTPE 2709
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  873 PSvPRRMTPGRAPQQQPPPPVATSQHHP-GPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSRGMLPTAL 951
Cdd:PHA03247 2710 PA-PHALVSATPLPPGPAAARQASPALPaAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAV 2788
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  952 QNQDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASL----PKHQQVESPTGAGAGGDHRSQRGHAAsparpsrPGGP 1027
Cdd:PHA03247 2789 ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPlpppTSAQPTAPPPPPGPPPPSLPLGGSVA-------PGGD 2861
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1028 QSRaRVPSRAAPGKSEPPSK-------RPLSSKSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVPKWPSSSTPRGGKDADG 1100
Cdd:PHA03247 2862 VRR-RPPSRSPAAKPAAPARppvrrlaRPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ 2940
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767943731 1101 SLAKEEREPAIALAPRGGSLAPVKRPLPPPPGSSPRaSHVPSRLPPRSAATVSPVAGTH 1159
Cdd:PHA03247 2941 PPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPR-FRVPQPAPSREAPASSTPPLTG 2998
PHA03247 PHA03247
large tegument protein UL36; Provisional
355-927 1.14e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.24  E-value: 1.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  355 PEKPEPSSPSP-RAPASSQHPSVPASPQ-GRNAKDLLLDlknkilANGGAPRKPQLRakkaeeldlqsTEITGEEELGSR 432
Cdd:PHA03247 2484 AEARFPFAAGAaPDPGGGGPPDPDAPPApSRLAPAILPD------EPVGEPVHPRML-----------TWIRGLEELASD 2546
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  433 ED-------SPMSPSDTQDQKRtlrPPSRHGHSVVAPGRTAvRARMPALPRREgvdkpgfslaTQPR-PGAPPSASASPA 504
Cdd:PHA03247 2547 DAgdpppplPPAAPPAAPDRSV---PPPRPAPRPSEPAVTS-RARRPDAPPQS----------ARPRaPVDDRGDPRGPA 2612
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  505 HHASTQGTSHRPSLPASLNDndlvdSDEDERAVGSLHPKGAFAQPRPALSPSRQSPSSVLRDRS-SVHPGAKPASPARRT 583
Cdd:PHA03247 2613 PPSPLPPDTHAPDPPPPSPS-----PAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGrAAQASSPPQRPRRRA 2687
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  584 PHSGAAEEDSSASAPPsrlsPPHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMsssvsshlssrTQVSEG 663
Cdd:PHA03247 2688 ARPTVGSLTSLADPPP----PPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPA-----------GPATPG 2752
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  664 AEASdgeshgdgdredggrqaeataqtlRARPASghfhllrhkPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHPR 743
Cdd:PHA03247 2753 GPAR------------------------PARPPT---------TAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLP 2799
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  744 VPSHSDSHPKLSSGIHGDEEDEK----PLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADT 819
Cdd:PHA03247 2800 SPWDPADPPAAVLAPAAALPPAAspagPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPA 2879
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  820 HPqgKYSSLASKAqdVQQSTDadteghsPKAQPGStdrhaSPARPPAARSQQHPsvprrmtpgrapqqqPPPPVATSQHH 899
Cdd:PHA03247 2880 RP--PVRRLARPA--VSRSTE-------SFALPPD-----QPERPPQPQAPPPP---------------QPQPQPPPPPQ 2928
                         570       580
                  ....*....|....*....|....*...
gi 767943731  900 PGPQSRDAGRSPSQPRLSLTQAGRPRPT 927
Cdd:PHA03247 2929 PQPPPPPPPRPQPPLAPTTDPAGAGEPS 2956
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1537-1637 7.79e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.22  E-value: 7.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1537 PPQhAPRNITVVAVEgcHSFVIVDWDKATPGDVvTGYLVYSASYEDfirNKWS----TQASSVTHlpiENLKPNTRYYFK 1612
Cdd:COG3401   232 PPS-APTGLTATADT--PGSVTLSWDPVTESDA-TGYRVYRSNSGD---GPFTkvatVTTTSYTD---TGLTNGTTYYYR 301
                          90       100
                  ....*....|....*....|....*.
gi 767943731 1613 VQAQNPHG-YGPISPSVSFVTESDNP 1637
Cdd:COG3401   302 VTAVDAAGnESAPSNVVSVTTDLTPP 327
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
470-865 1.01e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.01  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  470 RMPALPRREGVDKPGFSLATQPRPgappsasaspahhastqgtshRPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQP 549
Cdd:PHA03307   95 LAPASPAREGSPTPPGPSSPDPPP---------------------PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPP 153
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  550 RPALSPSRqspssvlrdrssvhPGAKPASPARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLLPTQPHLSSPLSKGGKD 629
Cdd:PHA03307  154 AAGASPAA--------------VASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASS 219
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  630 GEDAPATNSNAPsrstmsssvsshlssRTQVSEGAEASDGESHGDGDREDGGRQAEATAQTLRARPASGHFHLLRHKPFA 709
Cdd:PHA03307  220 PAPAPGRSAADD---------------AGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGP 284
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  710 ANGRSPSRfsiGRGPRLQPSSSPQSTVPSRaHPRVPSHSDSHPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPiSRGW 789
Cdd:PHA03307  285 ASSSSSPR---ERSPSPSPSSPGSGPAPSS-PRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSR-PPPP 359
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767943731  790 EDLRRSPQRGASlhrkEPIPENPKSTGADTHPQGKYSSLASKAqdVQQSTDADTEGHSPKAQPGSTDRHAS--PARPP 865
Cdd:PHA03307  360 ADPSSPRKRPRP----SRAPSSPAASAGRPTRRRARAAVAGRA--RRRDATGRFPAGRPRPSPLDAGAASGafYARYP 431
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
534-977 1.85e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.05  E-value: 1.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  534 ERAVGSLHPKGAFAQPRPALSPSRQSPSSvlrdrssvhPGAKPASPARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLL 613
Cdd:PRK07764  379 ERLERRLGVAGGAGAPAAAAPSAAAAAPA---------AAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAP 449
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  614 PTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMSSSVSSHLSSRTQVSEGAEASDGESHGDGDRE--DGGRQA--EATAQ 689
Cdd:PRK07764  450 AGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRErwPEILAAvpKRSRK 529
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  690 TLRARPASGHFHLLR--------HKPFAANgrspsRFSIGRGPR-----LQPSSSPQSTVPSRAHPRVPSHSDSHPKLSS 756
Cdd:PRK07764  530 TWAILLPEATVLGVRgdtlvlgfSTGGLAR-----RFASPGNAEvlvtaLAEELGGDWQVEAVVGPAPGAAGGEGPPAPA 604
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  757 GIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASlhrKEPIPENPKSTGADTHPQGKYSSLASKAQDVQ 836
Cdd:PRK07764  605 SSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAA---PEHHPKHVAVPDASDGGDGWPAKAGGAAPAAP 681
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  837 QSTDADTEGHSPKAQPGSTDRHASPARPPAARSQQHPSVPRRmtpgrapqqqppppVATSQHHPGPQSRDAGRSPSQPRL 916
Cdd:PRK07764  682 PPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQ--------------AAQGASAPSPAADDPVPLPPEPDD 747
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767943731  917 sltQAGRPRPTSQGRSHSSSDPYTASSRGMLPTALqnqdEDAQGSYDDDSTEVEAQDVRAP 977
Cdd:PRK07764  748 ---PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPP----SEEEEMAEDDAPSMDDEDRRDA 801
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
850-1068 1.85e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.05  E-value: 1.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  850 AQPGSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGRSPSQPRLSLTQAGRPRPTSQ 929
Cdd:PRK07764  586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  930 GrshsssDPYTASSRGMLPTALQNQDEDAQGsyDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDHR 1009
Cdd:PRK07764  666 G------DGWPAKAGGAAPAAPPPAPAPAAP--AAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADD 737
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767943731 1010 SQRGHAAsPARPSRPGGPQSRARVPSRAAPGKSEPPSKRPlSSKSQQSVSAEDDEEEDA 1068
Cdd:PRK07764  738 PVPLPPE-PDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPP-SPPSEEEEMAEDDAPSMD 794
Pur_ac_phosph_N pfam16656
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple ...
1557-1632 2.34e-03

Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple acid phosphatase proteins.


Pssm-ID: 465220 [Multi-domain]  Cd Length: 93  Bit Score: 38.93  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  1557 VIVDWdkATPGDVVTGYLVYSASYEDfirNKWSTQASSVT------------HLPIENLKPNTRYYFKVQAQNphgyGPI 1624
Cdd:pfam16656   15 MTVSW--VTPSAVTSPVVQYGTSSSA---LTSTATATSSTyttgdggtgyihRATLTGLEPGTTYYYRVGDDN----GGW 85

                   ....*...
gi 767943731  1625 SPSVSFVT 1632
Cdd:pfam16656   86 SEVYSFTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
41-127 3.48e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 3.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731   41 PNKPLRVRVRS-SDDRLSVAWKAPRLSGAksprRSRGFLLGYGESGRK--MNYVPLTRDERTHEIKKLASESVYVVSLQS 117
Cdd:cd00063     1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGG----PITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRA 76
                          90
                  ....*....|
gi 767943731  118 MNSQGRSQPV 127
Cdd:cd00063    77 VNGGGESPPS 86
COG3979 COG3979
Chitodextrinase [Carbohydrate transport and metabolism];
1541-1654 5.12e-03

Chitodextrinase [Carbohydrate transport and metabolism];


Pssm-ID: 443178 [Multi-domain]  Cd Length: 369  Bit Score: 41.30  E-value: 5.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731 1541 APRNITVVAVEGchSFVIVDWDKATPGDVVTGYLVYSASyedfirNKWSTQASSVTHLpIENLKPNTRYYFKVQAQNPHG 1620
Cdd:COG3979     5 APTGLTASNVTS--SSVSLSWDASTDNVGVTGYDVYRGG------DQVATVTGLTAWT-VTGLTPGTEYTFTVGACDAAG 75
                          90       100       110
                  ....*....|....*....|....*....|....
gi 767943731 1621 YGPISPSVSFVTESDNPLLVVRPPGGEPIWIPFA 1654
Cdd:COG3979    76 NVSAASGTSTAMFGGSSTTLGSAEGVADTSGNLA 109
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
459-695 8.26e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 8.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  459 VVAPGRTAVRARMPALPRREGVDKPGFSLATQPRPGappsasaspAHHASTQGTSHRPSLPASLNDNDLVDSDEDERAVG 538
Cdd:PRK07764  587 VVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPA---------APAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHV 657
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  539 SLHPKGAFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLLPTQPH 618
Cdd:PRK07764  658 AVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADD 737
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943731  619 LSSPLSKGGKDGEDAPATNSNAPSRSTMSSSVSSHLSSRTQVSEGAEA--SDGESHGDGDREDGGRQA-EATAQTLRARP 695
Cdd:PRK07764  738 PVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMaeDDAPSMDDEDRRDAEEVAmELLEEELGAKK 817
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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