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Conserved domains on  [gi|767943729|ref|XP_011534492|]
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fibronectin type III domain-containing protein 1 isoform X1 [Homo sapiens]

Protein Classification

fibronectin type III domain-containing protein( domain architecture ID 13885110)

fibronectin type III (FN3) domain-containing protein may be involved in specific interactions with other molecules through its FN3 domain; similar to Homo sapiens interleukin-27 subunit beta that associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity; fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III domain-containing protein similar to mammalian interleukin-9 and interleukin-21 receptors, and vertebrate phytanoyl-CoA hydroxylase-interacting protein; fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh), also called ABI gene family member 3-binding protein (ABI3BP), with 2 repeats; fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh) and Drosophila melanogaster cytokine receptor (protein domeless); fibronectin type III domain-containing protein similar to mammalian interleukin-9 and interleukin-21 receptors, and vertebrate phytanoyl-CoA hydroxylase-interacting protein; fibronectin type III (FN3) domain-containing protein similar to human Target of Nesh-SH3 (Tarsh), also called ABI gene family member 3-binding protein (ABI3BP), with 2 repeats

Gene Ontology:  GO:0005515

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1635-1726 3.65e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.05  E-value: 3.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1635 APRNITVVAVEgcHSFVIVDWDK-ATPGDVVTGYLVYsasYEDFIRNKW---STQASSVTHLPIENLKPNTRYYFKVQAQ 1710
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPpEDDGGPITGYVVE---YREKGSGDWkevEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                          90
                  ....*....|....*.
gi 767943729 1711 NPHGYGPISPSVSFVT 1726
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 339-429 6.87e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 63.28  E-value: 6.87e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  339 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 418
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

                          90
                  ....*....|.
gi 767943729  419 GLGPHSKAFIV 429
Cdd:cd00063    81 GESPPSESVTV 91
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 609-1041 1.51e-11

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 69.81  E-value: 1.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  609 RPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQPR----PALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAe 684
Cdd:PHA03307   31 AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP- 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  685 eDSSASAPPSRLSPPHGGSSrllPTQPHLSSPLSKGGKDGEDAPATNSNAPsrstmsssvsshlssrtqVSEGAEASDGE 764
Cdd:PHA03307  110 -GPSSPDPPPPTPPPASPPP---SPAPDLSEMLRPVGSPGPPPAASPPAAG------------------ASPAAVASDAA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  765 SHGDGdredgGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHpRVPSHSDS 844
Cdd:PHA03307  168 SSRQA-----ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAG-ASSSDSSS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  845 HPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPqgkySSLAS 924
Cdd:PHA03307  242 SESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP----RASSS 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  925 KAQDVQQSTDADTEGHSPKAQPGStdrhaSPARPPA-ARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGR 1003
Cdd:PHA03307  318 SSSSRESSSSSTSSSSESSRGAAV-----SPGPSPSrSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 767943729 1004 SPSQPRL-----SLTQAGRPRPTSQGRSHSSSDPYTASSRGML 1041
Cdd:PHA03307  393 AVAGRARrrdatGRFPAGRPRPSPLDAGAASGAFYARYPLLTP 435
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 788-1329 2.20e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.03  E-value: 2.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  788 RPASGHFhllrhkPFAANG-RSPsrfsiGRGPRLQPSSSPQSTVPSRA-HPRVPSHSDSHPKLSSGIHGDEE---DEKPL 862
Cdd:PHA03247 2482 RPAEARF------PFAAGAaPDP-----GGGGPPDPDAPPAPSRLAPAiLPDEPVGEPVHPRMLTWIRGLEElasDDAGD 2550

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  863 PATVVndhvPSSSRQPisrgwedlrrSPQRGASLHRKEPIPENPKSTGADTHPqgkysslaskaqdvqqstDADTEGHSP 942
Cdd:PHA03247 2551 PPPPL----PPAAPPA----------APDRSVPPPRPAPRPSEPAVTSRARRP------------------DAPPQSARP 2598

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  943 KAQPGSTDRHASPARPPAARSQQHPsvPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAgrsPSQPRLSLTQagrpRPTS 1022
Cdd:PHA03247 2599 RAPVDDRGDPRGPAPPSPLPPDTHA--PDPPPPSPSPAANEPDPHPPPTVPPPERPRDD---PAPGRVSRPR----RARR 2669

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1023 QGRSHSSSDPYTASSRGMLPTALQN----QDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGA 1098
Cdd:PHA03247 2670 LGRAAQASSPPQRPRRRAARPTVGSltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1099 GGDHRSQRGHAASPARPSRPGGPQSRARVPSRAAPgksePPSKRPLSSkSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVP 1178
Cdd:PHA03247 2750 TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASP 2824

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1179 KwPSSSTPRGGKDADGSLAKEEREPAIALaprGGSLAP---VKRPLPPPPGSSPRAShvPSRLPPRSAATVSPVAGTHPW 1255
Cdd:PHA03247 2825 A-GPLPPPTSAQPTAPPPPPGPPPPSLPL---GGSVAPggdVRRRPPSRSPAAKPAA--PARPPVRRLARPAVSRSTESF 2898

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767943729 1256 PQyttraPPGHFSTTPMLSLRQRMMharfRNPLSRQPARPSYRQGYNGRPNVEGKVLPGSNGKPNGQRIINGPQ 1329
Cdd:PHA03247 2899 AL-----PPDQPERPPQPQAPPPPQ----PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 238-331 2.27e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 55.97  E-value: 2.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  238 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGE--LARWDYKQIANRRVLIENLIPDTVYEFAVRIS 315
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSW-TPPEDDGGPIT---GYVVEYREKGSgdWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                          90
                  ....*....|....*.
gi 767943729  316 QGERDGKWSTSVFQRT 331
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 40-120 3.00e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


:

Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 49.92  E-value: 3.00e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729     40 PLKPRHVKLLS-TKMGLKVTWDPPKDATSR-PVEHYNIAYGKSLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHS 117
Cdd:smart00060    1 PSPPSNLRVTDvTSTSVTLSWEPPPDDGITgYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80


                    ...
gi 767943729    118 GVS 120
Cdd:smart00060   81 GEG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 135-221 4.05e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  135 PNKPLRVRVRS-SDDRLSVAWKAPRLSGAksprRSRGFLLGYGESGRK--MNYVPLTRDERTHEIKKLASESVYVVSLQS 211
Cdd:cd00063     1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGG----PITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRA 76

                          90
                  ....*....|
gi 767943729  212 MNSQGRSQPV 221
Cdd:cd00063    77 VNGGGESPPS 86
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1635-1726 3.65e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.05  E-value: 3.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1635 APRNITVVAVEgcHSFVIVDWDK-ATPGDVVTGYLVYsasYEDFIRNKW---STQASSVTHLPIENLKPNTRYYFKVQAQ 1710
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPpEDDGGPITGYVVE---YREKGSGDWkevEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                          90
                  ....*....|....*.
gi 767943729 1711 NPHGYGPISPSVSFVT 1726
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 339-429 6.87e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 63.28  E-value: 6.87e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  339 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 418
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

                          90
                  ....*....|.
gi 767943729  419 GLGPHSKAFIV 429
Cdd:cd00063    81 GESPPSESVTV 91
fn3 pfam00041
Fibronectin type III domain;
339-424 8.11e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 8.11e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729   339 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 418
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79


                   ....*.
gi 767943729   419 GLGPHS 424
Cdd:pfam00041   80 GEGPPS 85
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 609-1041 1.51e-11

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 69.81  E-value: 1.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  609 RPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQPR----PALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAe 684
Cdd:PHA03307   31 AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP- 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  685 eDSSASAPPSRLSPPHGGSSrllPTQPHLSSPLSKGGKDGEDAPATNSNAPsrstmsssvsshlssrtqVSEGAEASDGE 764
Cdd:PHA03307  110 -GPSSPDPPPPTPPPASPPP---SPAPDLSEMLRPVGSPGPPPAASPPAAG------------------ASPAAVASDAA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  765 SHGDGdredgGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHpRVPSHSDS 844
Cdd:PHA03307  168 SSRQA-----ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAG-ASSSDSSS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  845 HPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPqgkySSLAS 924
Cdd:PHA03307  242 SESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP----RASSS 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  925 KAQDVQQSTDADTEGHSPKAQPGStdrhaSPARPPA-ARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGR 1003
Cdd:PHA03307  318 SSSSRESSSSSTSSSSESSRGAAV-----SPGPSPSrSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 767943729 1004 SPSQPRL-----SLTQAGRPRPTSQGRSHSSSDPYTASSRGML 1041
Cdd:PHA03307  393 AVAGRARrrdatGRFPAGRPRPSPLDAGAASGAFYARYPLLTP 435
PHA03247 PHA03247
large tegument protein UL36; Provisional
 788-1329 2.20e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.03  E-value: 2.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  788 RPASGHFhllrhkPFAANG-RSPsrfsiGRGPRLQPSSSPQSTVPSRA-HPRVPSHSDSHPKLSSGIHGDEE---DEKPL 862
Cdd:PHA03247 2482 RPAEARF------PFAAGAaPDP-----GGGGPPDPDAPPAPSRLAPAiLPDEPVGEPVHPRMLTWIRGLEElasDDAGD 2550

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  863 PATVVndhvPSSSRQPisrgwedlrrSPQRGASLHRKEPIPENPKSTGADTHPqgkysslaskaqdvqqstDADTEGHSP 942
Cdd:PHA03247 2551 PPPPL----PPAAPPA----------APDRSVPPPRPAPRPSEPAVTSRARRP------------------DAPPQSARP 2598

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  943 KAQPGSTDRHASPARPPAARSQQHPsvPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAgrsPSQPRLSLTQagrpRPTS 1022
Cdd:PHA03247 2599 RAPVDDRGDPRGPAPPSPLPPDTHA--PDPPPPSPSPAANEPDPHPPPTVPPPERPRDD---PAPGRVSRPR----RARR 2669

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1023 QGRSHSSSDPYTASSRGMLPTALQN----QDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGA 1098
Cdd:PHA03247 2670 LGRAAQASSPPQRPRRRAARPTVGSltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1099 GGDHRSQRGHAASPARPSRPGGPQSRARVPSRAAPgksePPSKRPLSSkSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVP 1178
Cdd:PHA03247 2750 TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASP 2824

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1179 KwPSSSTPRGGKDADGSLAKEEREPAIALaprGGSLAP---VKRPLPPPPGSSPRAShvPSRLPPRSAATVSPVAGTHPW 1255
Cdd:PHA03247 2825 A-GPLPPPTSAQPTAPPPPPGPPPPSLPL---GGSVAPggdVRRRPPSRSPAAKPAA--PARPPVRRLARPAVSRSTESF 2898

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767943729 1256 PQyttraPPGHFSTTPMLSLRQRMMharfRNPLSRQPARPSYRQGYNGRPNVEGKVLPGSNGKPNGQRIINGPQ 1329
Cdd:PHA03247 2899 AL-----PPDQPERPPQPQAPPPPQ----PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 238-331 2.27e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 55.97  E-value: 2.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  238 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGE--LARWDYKQIANRRVLIENLIPDTVYEFAVRIS 315
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSW-TPPEDDGGPIT---GYVVEYREKGSgdWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                          90
                  ....*....|....*.
gi 767943729  316 QGERDGKWSTSVFQRT 331
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1635-1716 5.02e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 51.85  E-value: 5.02e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729   1635 APRNITVVAVEGchSFVIVDWDKAtPGDVVTGYLV-YSASYEDfIRNKWSTQASSV--THLPIENLKPNTRYYFKVQAQN 1711
Cdd:smart00060    3 PPSNLRVTDVTS--TSVTLSWEPP-PDDGITGYIVgYRVEYRE-EGSEWKEVNVTPssTSYTLTGLKPGTEYEFRVRAVN 78


                    ....*
gi 767943729   1712 PHGYG 1716
Cdd:smart00060   79 GAGEG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 40-120 3.00e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 49.92  E-value: 3.00e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729     40 PLKPRHVKLLS-TKMGLKVTWDPPKDATSR-PVEHYNIAYGKSLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHS 117
Cdd:smart00060    1 PSPPSNLRVTDvTSTSVTLSWEPPPDDGITgYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80


                    ...
gi 767943729    118 GVS 120
Cdd:smart00060   81 GEG 83
fn3 pfam00041
Fibronectin type III domain;
1635-1719 4.12e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 49.34  E-value: 4.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  1635 APRNITVVAVEgcHSFVIVDWDKATPGD-VVTGYLVYSASYEDFIRNKWSTQASSVTHLPIENLKPNTRYYFKVQAQNPH 1713
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNgPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79


                   ....*.
gi 767943729  1714 GYGPIS 1719
Cdd:pfam00041   80 GEGPPS 85
fn3 pfam00041
Fibronectin type III domain;
238-324 9.84e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 48.18  E-value: 9.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729   238 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGELARWDYKQIAN--RRVLIENLIPDTVYEFAVRIS 315
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSW-TPPPDGNGPIT---GYEVEYRPKNSGEPWNEITVPGttTSVTLTGLKPGTEYEVRVQAV 76


                   ....*....
gi 767943729   316 QGERDGKWS 324
Cdd:pfam00041   77 NGGGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 339-421 1.20e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 47.99  E-value: 1.20e-06
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729    339 APENLNVWPVNgkPTVVAASWDALPETEGKvkEYILSYAPALKPFGA--KSLTYPGDTTSALVDGLQPGERYLFKIRATN 416
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGIT--GYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVN 78


                    ....*
gi 767943729    417 RRGLG 421
Cdd:smart00060   79 GAGEG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 40-127 1.61e-06

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.88  E-value: 1.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729   40 PLKPRHVKLLS-TKMGLKVTWDPPKDATSrPVEHYNIAYGK--SLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENH 116
Cdd:cd00063     1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGG-PITGYVVEYREkgSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                          90
                  ....*....|.
gi 767943729  117 SGVSRPVYRAE 127
Cdd:cd00063    80 GGESPPSESVT 90
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
240-481 2.51e-06

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 52.31  E-value: 2.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  240 PDDISVRVMSSQSVLVSWvDPVLEKqkkvvASRQYTVrYREKGELARWdyKQIANRRVLI---ENLIPDTVYEFAVR-IS 315
Cdd:COG3401   236 PTGLTATADTPGSVTLSW-DPVTES-----DATGYRV-YRSNSGDGPF--TKVATVTTTSytdTGLTNGTTYYYRVTaVD 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  316 QGERDGKWSTSVfQRTPESAPTTAPENLNVwpVNGKPTVVAASWDalPETEGKVKEYILSYAPAlKPFGAKSLTYPGDTT 395
Cdd:COG3401   307 AAGNESAPSNVV-SVTTDLTPPAAPSGLTA--TAVGSSSITLSWT--ASSDADVTGYNVYRSTS-GGGTYTKIAETVTTT 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  396 SALVDGLQPGERYLFKIRATNRRGLGPHSKAFIVAMPTTskaDVEQNTEDNGKPEKPEPSSPSPRAPASSQHPSVPASPQ 475
Cdd:COG3401   381 SYTDTGLTPGTTYYYKVTAVDAAGNESAPSEEVSATTAS---AASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAV 457


                  ....*.
gi 767943729  476 GRNAKD 481
Cdd:COG3401   458 LADGGD 463
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 240-313 1.33e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 45.30  E-value: 1.33e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767943729    240 PDDISVRVMSSQSVLVSWVDPVLEKQKKvvasrqYTVRYREKGELARWDYKQI----ANRRVLIENLIPDTVYEFAVR 313
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSWEPPPDDGITG------YIVGYRVEYREEGSEWKEVnvtpSSTSYTLTGLKPGTEYEFRVR 75
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
30-163 3.04e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 45.76  E-value: 3.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729   30 ASSAAASVDHPLKPRHVKLLS-TKMGLKVTWDPPKDAtsrPVEHYNIaYGKSLKSLKYIKVN--AETYSFLIEDVEPGVV 106
Cdd:COG3401   317 VVSVTTDLTPPAAPSGLTATAvGSSSITLSWTASSDA---DVTGYNV-YRSTSGGGTYTKIAetVTTTSYTDTGLTPGTT 392

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767943729  107 YFVLLTAENHSGVsrpvyraESPPEKEVPNKPLRVRVRSSDDRLSVAWKAPRLSGAK 163
Cdd:COG3401   393 YYYKVTAVDAAGN-------ESAPSEEVSATTASAASGESLTASVDAVPLTDVAGAT 442
fn3 pfam00041
Fibronectin type III domain;
55-122 4.49e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.86  E-value: 4.49e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729    55 LKVTWDPPKDAtSRPVEHYNIAYGK--SLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHSGVSRP 122
Cdd:pfam00041   16 LTVSWTPPPDG-NGPITGYEVEYRPknSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 135-221 4.05e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  135 PNKPLRVRVRS-SDDRLSVAWKAPRLSGAksprRSRGFLLGYGESGRK--MNYVPLTRDERTHEIKKLASESVYVVSLQS 211
Cdd:cd00063     1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGG----PITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRA 76

                          90
                  ....*....|
gi 767943729  212 MNSQGRSQPV 221
Cdd:cd00063    77 VNGGGESPPS 86
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1635-1726 3.65e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.05  E-value: 3.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1635 APRNITVVAVEgcHSFVIVDWDK-ATPGDVVTGYLVYsasYEDFIRNKW---STQASSVTHLPIENLKPNTRYYFKVQAQ 1710
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPpEDDGGPITGYVVE---YREKGSGDWkevEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                          90
                  ....*....|....*.
gi 767943729 1711 NPHGYGPISPSVSFVT 1726
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 339-429 6.87e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 63.28  E-value: 6.87e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  339 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 418
Cdd:cd00063     3 PPTNLRVTDVT--STSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

                          90
                  ....*....|.
gi 767943729  419 GLGPHSKAFIV 429
Cdd:cd00063    81 GESPPSESVTV 91
fn3 pfam00041
Fibronectin type III domain;
339-424 8.11e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 8.11e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729   339 APENLNVWPVNgkPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRR 418
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79


                   ....*.
gi 767943729   419 GLGPHS 424
Cdd:pfam00041   80 GEGPPS 85
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 609-1041 1.51e-11

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 69.81  E-value: 1.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  609 RPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQPR----PALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAe 684
Cdd:PHA03307   31 AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEpptgPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP- 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  685 eDSSASAPPSRLSPPHGGSSrllPTQPHLSSPLSKGGKDGEDAPATNSNAPsrstmsssvsshlssrtqVSEGAEASDGE 764
Cdd:PHA03307  110 -GPSSPDPPPPTPPPASPPP---SPAPDLSEMLRPVGSPGPPPAASPPAAG------------------ASPAAVASDAA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  765 SHGDGdredgGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHpRVPSHSDS 844
Cdd:PHA03307  168 SSRQA-----ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAG-ASSSDSSS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  845 HPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPqgkySSLAS 924
Cdd:PHA03307  242 SESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP----RASSS 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  925 KAQDVQQSTDADTEGHSPKAQPGStdrhaSPARPPA-ARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGR 1003
Cdd:PHA03307  318 SSSSRESSSSSTSSSSESSRGAAV-----SPGPSPSrSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 767943729 1004 SPSQPRL-----SLTQAGRPRPTSQGRSHSSSDPYTASSRGML 1041
Cdd:PHA03307  393 AVAGRARrrdatGRFPAGRPRPSPLDAGAASGAFYARYPLLTP 435
PHA03247 PHA03247
large tegument protein UL36; Provisional
 788-1329 2.20e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.03  E-value: 2.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  788 RPASGHFhllrhkPFAANG-RSPsrfsiGRGPRLQPSSSPQSTVPSRA-HPRVPSHSDSHPKLSSGIHGDEE---DEKPL 862
Cdd:PHA03247 2482 RPAEARF------PFAAGAaPDP-----GGGGPPDPDAPPAPSRLAPAiLPDEPVGEPVHPRMLTWIRGLEElasDDAGD 2550

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  863 PATVVndhvPSSSRQPisrgwedlrrSPQRGASLHRKEPIPENPKSTGADTHPqgkysslaskaqdvqqstDADTEGHSP 942
Cdd:PHA03247 2551 PPPPL----PPAAPPA----------APDRSVPPPRPAPRPSEPAVTSRARRP------------------DAPPQSARP 2598

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  943 KAQPGSTDRHASPARPPAARSQQHPsvPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAgrsPSQPRLSLTQagrpRPTS 1022
Cdd:PHA03247 2599 RAPVDDRGDPRGPAPPSPLPPDTHA--PDPPPPSPSPAANEPDPHPPPTVPPPERPRDD---PAPGRVSRPR----RARR 2669

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1023 QGRSHSSSDPYTASSRGMLPTALQN----QDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGA 1098
Cdd:PHA03247 2670 LGRAAQASSPPQRPRRRAARPTVGSltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1099 GGDHRSQRGHAASPARPSRPGGPQSRARVPSRAAPgksePPSKRPLSSkSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVP 1178
Cdd:PHA03247 2750 TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASP 2824

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1179 KwPSSSTPRGGKDADGSLAKEEREPAIALaprGGSLAP---VKRPLPPPPGSSPRAShvPSRLPPRSAATVSPVAGTHPW 1255
Cdd:PHA03247 2825 A-GPLPPPTSAQPTAPPPPPGPPPPSLPL---GGSVAPggdVRRRPPSRSPAAKPAA--PARPPVRRLARPAVSRSTESF 2898

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767943729 1256 PQyttraPPGHFSTTPMLSLRQRMMharfRNPLSRQPARPSYRQGYNGRPNVEGKVLPGSNGKPNGQRIINGPQ 1329
Cdd:PHA03247 2899 AL-----PPDQPERPPQPQAPPPPQ----PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 238-331 2.27e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 55.97  E-value: 2.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  238 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGE--LARWDYKQIANRRVLIENLIPDTVYEFAVRIS 315
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSW-TPPEDDGGPIT---GYVVEYREKGSgdWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAV 77

                          90
                  ....*....|....*.
gi 767943729  316 QGERDGKWSTSVFQRT 331
Cdd:cd00063    78 NGGGESPPSESVTVTT 93
PHA03247 PHA03247
large tegument protein UL36; Provisional
 454-1107 4.77e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.88  E-value: 4.77e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  454 PSSPSPRAPASSQHPSVPAS---PQGRNAKDLLLDLKNKILANGGAPRKPQLRAKKAEELdlqsTEITGEEELGSRED-- 528
Cdd:PHA03247 2475 PGAPVYRRPAEARFPFAAGAapdPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRML----TWIRGLEELASDDAgd 2550

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  529 -----SPMSPSDTQDQKrtlRPPSRHGHSVVAPGRTAvRARMPALPRRegvdkpgfslATQPR-PGAPPSASASPAHHAS 602
Cdd:PHA03247 2551 pppplPPAAPPAAPDRS---VPPPRPAPRPSEPAVTS-RARRPDAPPQ----------SARPRaPVDDRGDPRGPAPPSP 2616

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  603 TQGTSHRPSLPASLNdndlvDSDEDERAVGSLHPKGAFAQPRPALSPSRQSPSSVLRDRS-SVHPGAKPASPARRTPHSG 681
Cdd:PHA03247 2617 LPPDTHAPDPPPPSP-----SPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGrAAQASSPPQRPRRRAARPT 2691

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  682 AAEEDSSASAPPsrlsPPHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMSSSvsshlssrTQVSEGAEAS 761
Cdd:PHA03247 2692 VGSLTSLADPPP----PPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA--------TPGGPARPAR 2759

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  762 DGESHGDGDREDGGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTV--PSRAHPRVP 839
Cdd:PHA03247 2760 PPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLppPTSAQPTAP 2839

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  840 SHSDSHPKLSSGIHGDEEDEKPL----PATVVNDHVPSSSRQPISR-GWEDLRRSPQrgaSLHRKEPIPENPKSTGADTH 914
Cdd:PHA03247 2840 PPPPGPPPPSLPLGGSVAPGGDVrrrpPSRSPAAKPAAPARPPVRRlARPAVSRSTE---SFALPPDQPERPPQPQAPPP 2916

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  915 PQgkysslaskaqdVQQSTDADTEGHSPKAQPGSTDRHASPARPPAARSQQHPSVPR----RMTPGRAPQQQPPPpvats 990
Cdd:PHA03247 2917 PQ------------PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQpwlgALVPGRVAVPRFRV----- 2979

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  991 qhhpgPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRS---HSSSDPYTASSRGMLPTALQNQDEDAQGSYDDDSTEVEAQD 1067
Cdd:PHA03247 2980 -----PQPAPSREAPASSTPPLTGHSLSRVSSWASSlalHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEA 3054

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|
gi 767943729 1068 VRApahaarAKEAAASLPKHQQVESPTGAGAGGDHRSQRG 1107
Cdd:PHA03247 3055 LDP------LPPEPHDPFAHEPDPATPEAGARESPSSQFG 3088
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 901-1330 4.84e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 61.73  E-value: 4.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  901 PIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHSPKAQPGSTDRHASPARPPAARSQQHPSVPRRMTPgrAPQ 980
Cdd:PHA03307   78 EAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASP--PAA 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  981 QQPPPPVATSQHHPG---------PQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSrgmlPTALQNQDED 1051
Cdd:PHA03307  156 GASPAAVASDAASSRqaalplsspEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPA----PAPGRSAADD 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1052 AQGSYDDDSTEVEAQDVRAPAHAARakeaaasLPKHQQVESPT--GAGAGGDHRSQRghaASPARPSrpGGPQSRARVPS 1129
Cdd:PHA03307  232 AGASSSDSSSSESSGCGWGPENECP-------LPRPAPITLPTriWEASGWNGPSSR---PGPASSS--SSPRERSPSPS 299

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1130 RAAPGKSEPPSKRPLSSKSQQSVSAEDDEEEDAGFfkggkedlLSSSVPKWPSSSTPRGGKDADGSlakeerepaialAP 1209
Cdd:PHA03307  300 PSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSE--------SSRGAAVSPGPSPSRSPSPSRPP------------PP 359

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1210 RGGSlaPVKRPLPPPPGSSPRASHVPSRLPPRSAATVSPvagthpwpqyttrappghfsttpmlslRQRMMHARFRNPLS 1289
Cdd:PHA03307  360 ADPS--SPRKRPRPSRAPSSPAASAGRPTRRRARAAVAG---------------------------RARRRDATGRFPAG 410

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 767943729 1290 RQPARPSYRQGYNGRPNVE-------GKVLPGSNGKPNGqRIINGPQG 1330
Cdd:PHA03307  411 RPRPSPLDAGAASGAFYARyplltpsGEPWPGSPPPPPG-RVRYGGLG 457
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1635-1716 5.02e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 51.85  E-value: 5.02e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729   1635 APRNITVVAVEGchSFVIVDWDKAtPGDVVTGYLV-YSASYEDfIRNKWSTQASSV--THLPIENLKPNTRYYFKVQAQN 1711
Cdd:smart00060    3 PPSNLRVTDVTS--TSVTLSWEPP-PDDGITGYIVgYRVEYRE-EGSEWKEVNVTPssTSYTLTGLKPGTEYEFRVRAVN 78


                    ....*
gi 767943729   1712 PHGYG 1716
Cdd:smart00060   79 GAGEG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 40-120 3.00e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 49.92  E-value: 3.00e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729     40 PLKPRHVKLLS-TKMGLKVTWDPPKDATSR-PVEHYNIAYGKSLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHS 117
Cdd:smart00060    1 PSPPSNLRVTDvTSTSVTLSWEPPPDDGITgYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80


                    ...
gi 767943729    118 GVS 120
Cdd:smart00060   81 GEG 83
fn3 pfam00041
Fibronectin type III domain;
1635-1719 4.12e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 49.34  E-value: 4.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  1635 APRNITVVAVEgcHSFVIVDWDKATPGD-VVTGYLVYSASYEDFIRNKWSTQASSVTHLPIENLKPNTRYYFKVQAQNPH 1713
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPPDGNgPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79


                   ....*.
gi 767943729  1714 GYGPIS 1719
Cdd:pfam00041   80 GEGPPS 85
fn3 pfam00041
Fibronectin type III domain;
238-324 9.84e-07

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 48.18  E-value: 9.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729   238 DVPDDISVRVMSSQSVLVSWvDPVLEKQKKVVasrQYTVRYREKGELARWDYKQIAN--RRVLIENLIPDTVYEFAVRIS 315
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSW-TPPPDGNGPIT---GYEVEYRPKNSGEPWNEITVPGttTSVTLTGLKPGTEYEVRVQAV 76


                   ....*....
gi 767943729   316 QGERDGKWS 324
Cdd:pfam00041   77 NGGGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 339-421 1.20e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 47.99  E-value: 1.20e-06
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729    339 APENLNVWPVNgkPTVVAASWDALPETEGKvkEYILSYAPALKPFGA--KSLTYPGDTTSALVDGLQPGERYLFKIRATN 416
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGIT--GYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVN 78


                    ....*
gi 767943729    417 RRGLG 421
Cdd:smart00060   79 GAGEG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 40-127 1.61e-06

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.88  E-value: 1.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729   40 PLKPRHVKLLS-TKMGLKVTWDPPKDATSrPVEHYNIAYGK--SLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENH 116
Cdd:cd00063     1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGG-PITGYVVEYREkgSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                          90
                  ....*....|.
gi 767943729  117 SGVSRPVYRAE 127
Cdd:cd00063    80 GGESPPSESVT 90
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 447-826 2.38e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 52.87  E-value: 2.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  447 GKPEKPEPSSPSPRAPassqhPSVPASPQGRNAKDLLLDLKnkilANGGAPRKPQLRAKKAEELDLQSTEITGEeelgSR 526
Cdd:PHA03307  104 GSPTPPGPSSPDPPPP-----TPPPASPPPSPAPDLSEMLR----PVGSPGPPPAASPPAAGASPAAVASDAAS----SR 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  527 EDSPMSPSdTQDQKRTLRPPSRHGHSVVAPGRTAVRARMPALPRREGVDKPGFSLATQPRPGAPPSASASPAHHASTQGT 606
Cdd:PHA03307  171 QAALPLSS-PEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGW 249

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  607 SHRPSLPASLNDNDLVDSDEDERAVGSLHPkgafaqPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEED 686
Cdd:PHA03307  250 GPENECPLPRPAPITLPTRIWEASGWNGPS------SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRE 323

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  687 SSASAPPSRLSPPHGGSSRllPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMSSSVSSHLSSRTQVSEGAEASDGesh 766
Cdd:PHA03307  324 SSSSSTSSSSESSRGAAVS--PGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRA--- 398

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  767 gdgdredggRQAEATAQTLRARPASGhfhllrhkPFAANGRSPSRFSigRGPRLQPSSSP 826
Cdd:PHA03307  399 ---------RRRDATGRFPAGRPRPS--------PLDAGAASGAFYA--RYPLLTPSGEP 439
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
240-481 2.51e-06

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 52.31  E-value: 2.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  240 PDDISVRVMSSQSVLVSWvDPVLEKqkkvvASRQYTVrYREKGELARWdyKQIANRRVLI---ENLIPDTVYEFAVR-IS 315
Cdd:COG3401   236 PTGLTATADTPGSVTLSW-DPVTES-----DATGYRV-YRSNSGDGPF--TKVATVTTTSytdTGLTNGTTYYYRVTaVD 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  316 QGERDGKWSTSVfQRTPESAPTTAPENLNVwpVNGKPTVVAASWDalPETEGKVKEYILSYAPAlKPFGAKSLTYPGDTT 395
Cdd:COG3401   307 AAGNESAPSNVV-SVTTDLTPPAAPSGLTA--TAVGSSSITLSWT--ASSDADVTGYNVYRSTS-GGGTYTKIAETVTTT 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  396 SALVDGLQPGERYLFKIRATNRRGLGPHSKAFIVAMPTTskaDVEQNTEDNGKPEKPEPSSPSPRAPASSQHPSVPASPQ 475
Cdd:COG3401   381 SYTDTGLTPGTTYYYKVTAVDAAGNESAPSEEVSATTAS---AASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAV 457


                  ....*.
gi 767943729  476 GRNAKD 481
Cdd:COG3401   458 LADGGD 463
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 240-313 1.33e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 45.30  E-value: 1.33e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767943729    240 PDDISVRVMSSQSVLVSWVDPVLEKQKKvvasrqYTVRYREKGELARWDYKQI----ANRRVLIENLIPDTVYEFAVR 313
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSWEPPPDDGITG------YIVGYRVEYREEGSEWKEVnvtpSSTSYTLTGLKPGTEYEFRVR 75
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1629-1731 1.83e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 49.62  E-value: 1.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1629 DLPPQHAPRNITVVAVEGchSFVIVDWDKATPGDVvTGYLVYSASYEDFIRNKWSTQASSVTHLpIENLKPNTRYYFKVQ 1708
Cdd:COG3401   323 DLTPPAAPSGLTATAVGS--SSITLSWTASSDADV-TGYNVYRSTSGGGTYTKIAETVTTTSYT-DTGLTPGTTYYYKVT 398

                          90       100
                  ....*....|....*....|....
gi 767943729 1709 AQNPHG-YGPISPSVSFVTESDNP 1731
Cdd:COG3401   399 AVDAAGnESAPSEEVSATTASAAS 422
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
249-445 2.99e-05

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 49.17  E-value: 2.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  249 SSQSVLVSWVDPVlekqkkvVASRqYTVRYREKGElaRWDYKQIANRRVLIENLIPDTVYEFAVR-ISQGERDGKWSTSV 327
Cdd:COG4733   550 AVTTLTVSWDAPA-------GAVA-YEVEWRRDDG--NWVSVPRTSGTSFEVPGIYAGDYEVRVRaINALGVSSAWAASS 619

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  328 -FQRTPESAPTTAPENLNVWPVNGKptvVAASWDALPETEgkVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGE 406
Cdd:COG4733   620 eTTVTGKTAPPPAPTGLTATGGLGG---ITLSWSFPVDAD--TLRTEIRYSTTGDWASATVAQALYPGNTYTLAGLKAGQ 694

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767943729  407 RYLFKIRATNRRGLgpHSKAFIVAMPTTSKADVEQNTED 445
Cdd:COG4733   695 TYYYRARAVDRSGN--VSAWWVSGQASADAAGILDAITG 731
PHA03247 PHA03247
large tegument protein UL36; Provisional
 818-1253 5.71e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 5.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  818 PRLQPSSSPQSTVPSRAHPRVP--------SHSDSHPKLSSG-IHGDEEDEKPLPAtvvndhvPSSSRQPISRGWEDLRR 888
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPAPRPSepavtsraRRPDAPPQSARPrAPVDDRGDPRGPA-------PPSPLPPDTHAPDPPPP 2629

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  889 SPQRGASLHRKEPIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDAD--TEGHSPKAQPGSTDRHASPARPPAARSQQH 966
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASspPQRPRRRAARPTVGSLTSLADPPPPPPTPE 2709

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  967 PSvPRRMTPGRAPQQQPPPPVATSQHHP-GPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSRGMLPTAL 1045
Cdd:PHA03247 2710 PA-PHALVSATPLPPGPAAARQASPALPaAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAV 2788

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1046 QNQDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASL----PKHQQVESPTGAGAGGDHRSQRGHAAsparpsrPGGP 1121
Cdd:PHA03247 2789 ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPlpppTSAQPTAPPPPPGPPPPSLPLGGSVA-------PGGD 2861

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1122 QSRaRVPSRAAPGKSEPPSK-------RPLSSKSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVPKWPSSSTPRGGKDADG 1194
Cdd:PHA03247 2862 VRR-RPPSRSPAAKPAAPARppvrrlaRPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ 2940

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767943729 1195 SLAKEEREPAIALAPRGGSLAPVKRPLPPPPGSSPRaSHVPSRLPPRSAATVSPVAGTH 1253
Cdd:PHA03247 2941 PPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPR-FRVPQPAPSREAPASSTPPLTG 2998
PHA03247 PHA03247
large tegument protein UL36; Provisional
 449-1021 5.86e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 5.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  449 PEKPEPSSPSP-RAPASSQHPSVPASPQ-GRNAKDLLLDlknkilANGGAPRKPQLRakkaeeldlqsTEITGEEELGSR 526
Cdd:PHA03247 2484 AEARFPFAAGAaPDPGGGGPPDPDAPPApSRLAPAILPD------EPVGEPVHPRML-----------TWIRGLEELASD 2546

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  527 ED-------SPMSPSDTQDQKRtlrPPSRHGHSVVAPGRTAvRARMPALPRREgvdkpgfslaTQPR-PGAPPSASASPA 598
Cdd:PHA03247 2547 DAgdpppplPPAAPPAAPDRSV---PPPRPAPRPSEPAVTS-RARRPDAPPQS----------ARPRaPVDDRGDPRGPA 2612

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  599 HHASTQGTSHRPSLPASLNDndlvdSDEDERAVGSLHPKGAFAQPRPALSPSRQSPSSVLRDRS-SVHPGAKPASPARRT 677
Cdd:PHA03247 2613 PPSPLPPDTHAPDPPPPSPS-----PAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGrAAQASSPPQRPRRRA 2687

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  678 PHSGAAEEDSSASAPPsrlsPPHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMsssvsshlssrTQVSEG 757
Cdd:PHA03247 2688 ARPTVGSLTSLADPPP----PPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPA-----------GPATPG 2752

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  758 AEASdgeshgdgdredggrqaeataqtlRARPASghfhllrhkPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHPR 837
Cdd:PHA03247 2753 GPAR------------------------PARPPT---------TAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLP 2799

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  838 VPSHSDSHPKLSSGIHGDEEDEK----PLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADT 913
Cdd:PHA03247 2800 SPWDPADPPAAVLAPAAALPPAAspagPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPA 2879

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  914 HPqgKYSSLASKAqdVQQSTDadteghsPKAQPGStdrhaSPARPPAARSQQHPsvprrmtpgrapqqqPPPPVATSQHH 993
Cdd:PHA03247 2880 RP--PVRRLARPA--VSRSTE-------SFALPPD-----QPERPPQPQAPPPP---------------QPQPQPPPPPQ 2928

                         570       580
                  ....*....|....*....|....*...
gi 767943729  994 PGPQSRDAGRSPSQPRLSLTQAGRPRPT 1021
Cdd:PHA03247 2929 PQPPPPPPPRPQPPLAPTTDPAGAGEPS 2956
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
30-163 3.04e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 45.76  E-value: 3.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729   30 ASSAAASVDHPLKPRHVKLLS-TKMGLKVTWDPPKDAtsrPVEHYNIaYGKSLKSLKYIKVN--AETYSFLIEDVEPGVV 106
Cdd:COG3401   317 VVSVTTDLTPPAAPSGLTATAvGSSSITLSWTASSDA---DVTGYNV-YRSTSGGGTYTKIAetVTTTSYTDTGLTPGTT 392

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767943729  107 YFVLLTAENHSGVsrpvyraESPPEKEVPNKPLRVRVRSSDDRLSVAWKAPRLSGAK 163
Cdd:COG3401   393 YYYKVTAVDAAGN-------ESAPSEEVSATTASAASGESLTASVDAVPLTDVAGAT 442
fn3 pfam00041
Fibronectin type III domain;
55-122 4.49e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.86  E-value: 4.49e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729    55 LKVTWDPPKDAtSRPVEHYNIAYGK--SLKSLKYIKVNAETYSFLIEDVEPGVVYFVLLTAENHSGVSRP 122
Cdd:pfam00041   16 LTVSWTPPPDG-NGPITGYEVEYRPknSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 564-959 4.70e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.16  E-value: 4.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  564 RMPALPRREGVDKPGFSLATQPRPgappsasaspahhastqgtshRPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQP 643
Cdd:PHA03307   95 LAPASPAREGSPTPPGPSSPDPPP---------------------PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPP 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  644 RPALSPSRqspssvlrdrssvhPGAKPASPARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLLPTQPHLSSPLSKGGKD 723
Cdd:PHA03307  154 AAGASPAA--------------VASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASS 219

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  724 GEDAPATNSNAPsrstmsssvsshlssRTQVSEGAEASDGESHGDGDREDGGRQAEATAQTLRARPASGHFHLLRHKPFA 803
Cdd:PHA03307  220 PAPAPGRSAADD---------------AGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGP 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  804 ANGRSPSRfsiGRGPRLQPSSSPQSTVPSRaHPRVPSHSDSHPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPiSRGW 883
Cdd:PHA03307  285 ASSSSSPR---ERSPSPSPSSPGSGPAPSS-PRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSR-PPPP 359

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767943729  884 EDLRRSPQRGASlhrkEPIPENPKSTGADTHPQGKYSSLASKAqdVQQSTDADTEGHSPKAQPGSTDRHAS--PARPP 959
Cdd:PHA03307  360 ADPSSPRKRPRP----SRAPSSPAASAGRPTRRRARAAVAGRA--RRRDATGRFPAGRPRPSPLDAGAASGafYARYP 431
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1631-1731 1.04e-03

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 43.84  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1631 PPQhAPRNITVVAVEgcHSFVIVDWDKATPGDVvTGYLVYSASYEDfirNKWS----TQASSVTHlpiENLKPNTRYYFK 1706
Cdd:COG3401   232 PPS-APTGLTATADT--PGSVTLSWDPVTESDA-TGYRVYRSNSGD---GPFTkvatVTTTSYTD---TGLTNGTTYYYR 301

                          90       100
                  ....*....|....*....|....*.
gi 767943729 1707 VQAQNPHG-YGPISPSVSFVTESDNP 1731
Cdd:COG3401   302 VTAVDAAGnESAPSNVVSVTTDLTPP 327
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 628-1071 1.30e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 1.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  628 ERAVGSLHPKGAFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPAsPARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLL 707
Cdd:PRK07764  391 AGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPA-PAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPA 469

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  708 PTQPHLSSPLSKGGKDGEDAPATnsnapsrstmsssvsshlssRTQVSEGAEASDGESHGDGDRE--DGGRQA--EATAQ 783
Cdd:PRK07764  470 PAAAPEPTAAPAPAPPAAPAPAA--------------------APAAPAAPAAPAGADDAATLRErwPEILAAvpKRSRK 529

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  784 TLRARPASGHFHLLR--------HKPFAANgrspsRFSIGRGPR-----LQPSSSPQSTVPSRAHPRVPSHSDSHPKLSS 850
Cdd:PRK07764  530 TWAILLPEATVLGVRgdtlvlgfSTGGLAR-----RFASPGNAEvlvtaLAEELGGDWQVEAVVGPAPGAAGGEGPPAPA 604

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  851 GIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLRRSPQRGASlhrKEPIPENPKSTGADTHPQGKYSSLASKAQDVQ 930
Cdd:PRK07764  605 SSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAA---PEHHPKHVAVPDASDGGDGWPAKAGGAAPAAP 681

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  931 QSTDADTEGHSPKAQPGSTDRHASPARPPAARSQQHPSVPRRmtpgrapqqqppppVATSQHHPGPQSRDAGRSPSQPRL 1010
Cdd:PRK07764  682 PPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQ--------------AAQGASAPSPAADDPVPLPPEPDD 747

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767943729 1011 sltQAGRPRPTSQGRSHSSSDPYTASSRGMLPTALqnqdEDAQGSYDDDSTEVEAQDVRAP 1071
Cdd:PRK07764  748 ---PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPP----SEEEEMAEDDAPSMDDEDRRDA 801
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 944-1162 1.64e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.44  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  944 AQPGSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGRSPSQPRLSLTQAGRPRPTSQ 1023
Cdd:PRK07764  586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1024 GrshsssDPYTASSRGMLPTALQNQDEDAQGsyDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDHR 1103
Cdd:PRK07764  666 G------DGWPAKAGGAAPAAPPPAPAPAAP--AAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADD 737

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767943729 1104 SQRGHAAsPARPSRPGGPQSRARVPSRAAPGKSEPPSKRPlSSKSQQSVSAEDDEEEDA 1162
Cdd:PRK07764  738 PVPLPPE-PDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPP-SPPSEEEEMAEDDAPSMD 794
Pur_ac_phosph_N pfam16656
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple ...
 1651-1726 2.64e-03

Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple acid phosphatase proteins.


Pssm-ID: 465220 [Multi-domain]  Cd Length: 93  Bit Score: 38.93  E-value: 2.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  1651 VIVDWdkATPGDVVTGYLVYSASYEDfirNKWSTQASSVT------------HLPIENLKPNTRYYFKVQAQNphgyGPI 1718
Cdd:pfam16656   15 MTVSW--VTPSAVTSPVVQYGTSSSA---LTSTATATSSTyttgdggtgyihRATLTGLEPGTTYYYRVGDDN----GGW 85


                   ....*...
gi 767943729  1719 SPSVSFVT 1726
Cdd:pfam16656   86 SEVYSFTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 135-221 4.05e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 4.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  135 PNKPLRVRVRS-SDDRLSVAWKAPRLSGAksprRSRGFLLGYGESGRK--MNYVPLTRDERTHEIKKLASESVYVVSLQS 211
Cdd:cd00063     1 PSPPTNLRVTDvTSTSVTLSWTPPEDDGG----PITGYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRA 76

                          90
                  ....*....|
gi 767943729  212 MNSQGRSQPV 221
Cdd:cd00063    77 VNGGGESPPS 86
COG3979 COG3979
Chitodextrinase [Carbohydrate transport and metabolism];
1635-1748 4.84e-03

Chitodextrinase [Carbohydrate transport and metabolism];


Pssm-ID: 443178 [Multi-domain]  Cd Length: 369  Bit Score: 41.30  E-value: 4.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1635 APRNITVVAVEGchSFVIVDWDKATPGDVVTGYLVYSASyedfirNKWSTQASSVTHLpIENLKPNTRYYFKVQAQNPHG 1714
Cdd:COG3979     5 APTGLTASNVTS--SSVSLSWDASTDNVGVTGYDVYRGG------DQVATVTGLTAWT-VTGLTPGTEYTFTVGACDAAG 75

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767943729 1715 YGPISPSVSFVTESDNPLLVVRPPGGEPIWIPFA 1748
Cdd:COG3979    76 NVSAASGTSTAMFGGSSTTLGSAEGVADTSGNLA 109
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
99-395 6.63e-03

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 41.14  E-value: 6.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729   99 EDVEPGVVYFVLLTAENHSGVSRPVYRAESPPEKEVPNKPLRVRVRS-SDDRLSVAWKAPRLSGAKsprrsrGFLLGYGE 177
Cdd:COG3401   197 GDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATAdTPGSVTLSWDPVTESDAT------GYRVYRSN 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  178 SGRKmNYVPLTRDERTHEI-KKLASESVYVVSLQSMNSQG-RSQPVYRAALTKRKISeedeLDVPDDISVRVMSSQSVLV 255
Cdd:COG3401   271 SGDG-PFTKVATVTTTSYTdTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTP----PAAPSGLTATAVGSSSITL 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  256 SWvDPVLEKQkkvVASrqYTVrYREKGELARWDY--KQIANRRVLIENLIPDTVYEFAVR-ISQgerDGKWSTSVFQRTP 332
Cdd:COG3401   346 SW-TASSDAD---VTG--YNV-YRSTSGGGTYTKiaETVTTTSYTDTGLTPGTTYYYKVTaVDA---AGNESAPSEEVSA 415

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767943729  333 ESAPTTAPENL----NVWPVNGKPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTT 395
Cdd:COG3401   416 TTASAASGESLtasvDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTT 482
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 553-789 7.90e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 7.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  553 VVAPGRTAVRARMPALPRREGVDKPGFSLATQPRPGappsasaspAHHASTQGTSHRPSLPASLNDNDLVDSDEDERAVG 632
Cdd:PRK07764  587 VVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPA---------APAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHV 657

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  633 SLHPKGAFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLLPTQPH 712
Cdd:PRK07764  658 AVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADD 737

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  713 LSSPLSKGGKDGEDAPATNSNAPSRSTMSSSVSSHLSSRTQVSEGAEA--SDGESHGDGDREDGGRQA-EATAQTLRARP 789
Cdd:PRK07764  738 PVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMaeDDAPSMDDEDRRDAEEVAmELLEEELGAKK 817
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 942-1265 8.03e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 8.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729  942 PKAQPGSTDRHASPARPPAAR---SQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGRSPSQPRLSLTQAGRP 1018
Cdd:PRK07764  413 AAAAPAAAAAPAPAAAPQPAPapaPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA 492

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1019 RPTSQGRSHSSSDPYTA--------------------SSRGMLPTA--LQNQDE----------DAQGSYDDDSTEVEAQ 1066
Cdd:PRK07764  493 APAAPAAPAAPAGADDAatlrerwpeilaavpkrsrkTWAILLPEAtvLGVRGDtlvlgfstggLARRFASPGNAEVLVT 572

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1067 DVRApahaarakeaaaSLPKHQQVE-----SPTGAGAGGDHRSQRGHAAS----PARPSRPGGPQSRARVPSRAAPGKSE 1137
Cdd:PRK07764  573 ALAE------------ELGGDWQVEavvgpAPGAAGGEGPPAPASSGPPEeaarPAAPAAPAAPAAPAPAGAAAAPAEAS 640

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767943729 1138 PPSKRPLSSKSQQSVSAEDDEEEDAGFFKGGKEDLLSSSVPKWPSSSTPRGGKDADGSLAKEEREPAIALAPRGGSLAPV 1217
Cdd:PRK07764  641 AAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQ 720

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 767943729 1218 KRPLPPPPGSSPRASHVPSRLPPrsAATVSPVAGTHPWPQYTTRAPPG 1265
Cdd:PRK07764  721 PPQAAQGASAPSPAADDPVPLPP--EPDDPPDPAGAPAQPPPPPAPAP 766
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
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