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Conserved domains on  [gi|767923709|ref|XP_011532193|]
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DALR anticodon-binding domain-containing protein 3 isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Anticodon_Ia_like super family cl12020
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This ...
 403-464 3.31e-07

Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This domain is found in a variety of class Ia aminoacyl tRNA synthetases, C-terminal to the catalytic core domain. It recognizes and specifically binds to the anticodon of the tRNA. Aminoacyl tRNA synthetases catalyze the transfer of cognate amino acids to the 3'-end of their tRNAs by specifically recognizing cognate from non-cognate amino acids. Members include valyl-, leucyl-, isoleucyl-, cysteinyl-, arginyl-, and methionyl-tRNA synthethases. This superfamily also includes a domain from MshC, an enzyme in the mycothiol biosynthetic pathway.


The actual alignment was detected with superfamily member smart00836:

Pssm-ID: 472259 [Multi-domain]  Cd Length: 122  Bit Score: 49.11  E-value: 3.31e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767923709   403 VMYNCARLATLFESYKcsmEQGLypTFPPVSSLDFSLLHDEGEWLLLFnSILPFPDLLSRTA 464
Cdd:smart00836   1 VQYAHARICSILRKAG---EAGE--TLPDIADADLSLLTEPEEWALLL-KLARFPEVLEAAA 56
 
Name Accession Description Interval E-value
DALR_1 smart00836
DALR anticodon binding domain; This all alpha helical domain is the anticodon binding domain ...
 403-464 3.31e-07

DALR anticodon binding domain; This all alpha helical domain is the anticodon binding domain of Arginyl tRNA synthetase. This domain is known as the DALR domain after characteristic conserved amino acids.


Pssm-ID: 214846 [Multi-domain]  Cd Length: 122  Bit Score: 49.11  E-value: 3.31e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767923709   403 VMYNCARLATLFESYKcsmEQGLypTFPPVSSLDFSLLHDEGEWLLLFnSILPFPDLLSRTA 464
Cdd:smart00836   1 VQYAHARICSILRKAG---EAGE--TLPDIADADLSLLTEPEEWALLL-KLARFPEVLEAAA 56
 
Name Accession Description Interval E-value
DALR_1 smart00836
DALR anticodon binding domain; This all alpha helical domain is the anticodon binding domain ...
 403-464 3.31e-07

DALR anticodon binding domain; This all alpha helical domain is the anticodon binding domain of Arginyl tRNA synthetase. This domain is known as the DALR domain after characteristic conserved amino acids.


Pssm-ID: 214846 [Multi-domain]  Cd Length: 122  Bit Score: 49.11  E-value: 3.31e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767923709   403 VMYNCARLATLFESYKcsmEQGLypTFPPVSSLDFSLLHDEGEWLLLFnSILPFPDLLSRTA 464
Cdd:smart00836   1 VQYAHARICSILRKAG---EAGE--TLPDIADADLSLLTEPEEWALLL-KLARFPEVLEAAA 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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