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Conserved domains on  [gi|767914037|ref|XP_011530943|]
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C-type lectin domain family 4 member F isoform X5 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1005088)

coiled-coil domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CCDC158 super family cl37899
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 207-567 7.86e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


The actual alignment was detected with superfamily member pfam15921:

Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.14  E-value: 7.86e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   207 EAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDA----TTLSLQTQMLRSS 282
Cdd:pfam15921  432 EALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSertvSDLTASLQEKERA 511

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   283 LEGTNAEIQRLKEDLEkadaLTFQTLNFLKSS---LENTSIELHVLSRGLENANSEIQMLNASLETantQAQLANSSLKN 359
Cdd:pfam15921  512 IEATNAEITKLRSRVD----LKLQELQHLKNEgdhLRNVQTECEALKLQMAEKDKVIEILRQQIEN---MTQLVGQHGRT 584

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   360 ANAeIYVLRGHLD-SVNDLRTQNQVLRNSLEGANAEIQGLK--------ENLQNTNALNSQTQAF--IKSSFDNTSAEIQ 428
Cdd:pfam15921  585 AGA-MQVEKAQLEkEINDRRLELQEFKILKDKKDAKIRELEarvsdlelEKVKLVNAGSERLRAVkdIKQERDQLLNEVK 663

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   429 FLRGHLERAGDEIHVLKR-------DLKMVT----AQTQKANGRLDQTDTQIQVFK------------------SEMENV 479
Cdd:pfam15921  664 TSRNELNSLSEDYEVLKRnfrnkseEMETTTnklkMQLKSAQSELEQTRNTLKSMEgsdghamkvamgmqkqitAKRGQI 743

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   480 NTLNAQIQVLNGHMKNASREIQTLKQgmkNASALTSQTQMLDSNLQKASAEIQRLRGDLE--NTKALTMEIQQEQSRLKT 557
Cdd:pfam15921  744 DALQSKIQFLEEAMTNANKEKHFLKE---EKNKLSQELSTVATEKNKMAGELEVLRSQERrlKEKVANMEVALDKASLQF 820

                          410
                   ....*....|..
gi 767914037   558 LHV--VITSQEQ 567
Cdd:pfam15921  821 AECqdIIQRQEQ 832
 
Name Accession Description Interval E-value
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 207-567 7.86e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.14  E-value: 7.86e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   207 EAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDA----TTLSLQTQMLRSS 282
Cdd:pfam15921  432 EALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSertvSDLTASLQEKERA 511

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   283 LEGTNAEIQRLKEDLEkadaLTFQTLNFLKSS---LENTSIELHVLSRGLENANSEIQMLNASLETantQAQLANSSLKN 359
Cdd:pfam15921  512 IEATNAEITKLRSRVD----LKLQELQHLKNEgdhLRNVQTECEALKLQMAEKDKVIEILRQQIEN---MTQLVGQHGRT 584

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   360 ANAeIYVLRGHLD-SVNDLRTQNQVLRNSLEGANAEIQGLK--------ENLQNTNALNSQTQAF--IKSSFDNTSAEIQ 428
Cdd:pfam15921  585 AGA-MQVEKAQLEkEINDRRLELQEFKILKDKKDAKIRELEarvsdlelEKVKLVNAGSERLRAVkdIKQERDQLLNEVK 663

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   429 FLRGHLERAGDEIHVLKR-------DLKMVT----AQTQKANGRLDQTDTQIQVFK------------------SEMENV 479
Cdd:pfam15921  664 TSRNELNSLSEDYEVLKRnfrnkseEMETTTnklkMQLKSAQSELEQTRNTLKSMEgsdghamkvamgmqkqitAKRGQI 743

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   480 NTLNAQIQVLNGHMKNASREIQTLKQgmkNASALTSQTQMLDSNLQKASAEIQRLRGDLE--NTKALTMEIQQEQSRLKT 557
Cdd:pfam15921  744 DALQSKIQFLEEAMTNANKEKHFLKE---EKNKLSQELSTVATEKNKMAGELEVLRSQERrlKEKVANMEVALDKASLQF 820

                          410
                   ....*....|..
gi 767914037   558 LHV--VITSQEQ 567
Cdd:pfam15921  821 AECqdIIQRQEQ 832
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 206-556 5.41e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 62.35  E-value: 5.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  206 REAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKD----ATTLSLQTQMLRS 281
Cdd:TIGR04523  52 KEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNdkeqKNKLEVELNKLEK 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  282 SLEGTNA-------EIQRLKEDLEKADAlTFQTLNFLKSSLENtsiELHVLSRGLENANSEIQMLNASLetanTQAQLAN 354
Cdd:TIGR04523 132 QKKENKKnidkfltEIKKKEKELEKLNN-KYNDLKKQKEELEN---ELNLLEKEKLNIQKNIDKIKNKL----LKLELLL 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  355 SSLKNANAEIYVLrghLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNT-----NALNSQTQAF------------IK 417
Cdd:TIGR04523 204 SNLKKKIQKNKSL---ESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTqtqlnQLKDEQNKIKkqlsekqkeleqNN 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  418 SSFDNTSAEIQFLRGHL-----ERAGDEIHVLKRDL-----KMVTAQTQ--KANGRLDQTDTQIQVFKSEMENVNT---- 481
Cdd:TIGR04523 281 KKIKELEKQLNQLKSEIsdlnnQKEQDWNKELKSELknqekKLEEIQNQisQNNKIISQLNEQISQLKKELTNSESense 360

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767914037  482 LNAQIQVLNGHMKNASREIQTLKQGMKNasaLTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLK 556
Cdd:TIGR04523 361 KQRELEEKQNEIEKLKKENQSYKQEIKN---LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLK 432
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 291-572 2.06e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 2.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 291 QRLKEDLEKADA-LTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETA-------NTQAQLANSSLKNANA 362
Cdd:COG1196  216 RELKEELKELEAeLLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELrleleelELELEEAQAEEYELLA 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 363 EIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQntnalnsqtqafikssfdntsAEIQFLRGHLERAGDEIH 442
Cdd:COG1196  296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE---------------------EELEELEEELEEAEEELE 354

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 443 VLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENvntLNAQIQVLNGHMKNASREIQTLKQgmkNASALTSQTQMLDS 522
Cdd:COG1196  355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLE---ALRAAAELAAQLEELEEAEEALLE---RLERLEEELEELEE 428

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 767914037 523 NLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQ 572
Cdd:COG1196  429 ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA 478
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
288-547 1.30e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 1.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 288 AEIQRLKEDLEKADALTFQTLNFLKS-----SLENTSIELHVLSRGLENANSEIQMLNAS-LETANTQAQLANSSLKNAN 361
Cdd:PRK03918 459 AELKRIEKELKEIEEKERKLRKELRElekvlKKESELIKLKELAEQLKELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLK 538

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 362 AEIYVLRGHLDSVNDLRtqnqvlrNSLEGANAEIQGLKENLQNtnaLNSQTQAFIKSSFDNTSAEIQFLR---------- 431
Cdd:PRK03918 539 GEIKSLKKELEKLEELK-------KKLAELEKKLDELEEELAE---LLKELEELGFESVEELEERLKELEpfyneylelk 608

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 432 ---GHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKS-----EMENVNT-----------LNAQIQVLNGH 492
Cdd:PRK03918 609 daeKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKkyseeEYEELREeylelsrelagLRAELEELEKR 688

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 767914037 493 MKNASREIQTLKQGMKNasalTSQTQMLDSNLQKASAEIQRLRGDLENTKALTME 547
Cdd:PRK03918 689 REEIKKTLEKLKEELEE----REKAKKELEKLEKALERVEELREKVKKYKALLKE 739
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 428-576 1.34e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 1.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   428 QFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGH-MKNASREIQTLKQG 506
Cdd:smart00787 140 KLLEGLKEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTeLDRAKEKLKKLLQE 219

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767914037   507 M----KNASALTSQTQMLDSNLQKASAEIQRLRGDLentkaltMEIQQ--EQSRLKTLHVVITSQEQLQRTQSISG 576
Cdd:smart00787 220 ImikvKKLEELEEELQELESKIEDLTNKKSELNTEI-------AEAEKklEQCRGFTFKEIEKLKEQLKLLQSLTG 288
 
Name Accession Description Interval E-value
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 207-567 7.86e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.14  E-value: 7.86e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   207 EAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDA----TTLSLQTQMLRSS 282
Cdd:pfam15921  432 EALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSertvSDLTASLQEKERA 511

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   283 LEGTNAEIQRLKEDLEkadaLTFQTLNFLKSS---LENTSIELHVLSRGLENANSEIQMLNASLETantQAQLANSSLKN 359
Cdd:pfam15921  512 IEATNAEITKLRSRVD----LKLQELQHLKNEgdhLRNVQTECEALKLQMAEKDKVIEILRQQIEN---MTQLVGQHGRT 584

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   360 ANAeIYVLRGHLD-SVNDLRTQNQVLRNSLEGANAEIQGLK--------ENLQNTNALNSQTQAF--IKSSFDNTSAEIQ 428
Cdd:pfam15921  585 AGA-MQVEKAQLEkEINDRRLELQEFKILKDKKDAKIRELEarvsdlelEKVKLVNAGSERLRAVkdIKQERDQLLNEVK 663

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   429 FLRGHLERAGDEIHVLKR-------DLKMVT----AQTQKANGRLDQTDTQIQVFK------------------SEMENV 479
Cdd:pfam15921  664 TSRNELNSLSEDYEVLKRnfrnkseEMETTTnklkMQLKSAQSELEQTRNTLKSMEgsdghamkvamgmqkqitAKRGQI 743

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   480 NTLNAQIQVLNGHMKNASREIQTLKQgmkNASALTSQTQMLDSNLQKASAEIQRLRGDLE--NTKALTMEIQQEQSRLKT 557
Cdd:pfam15921  744 DALQSKIQFLEEAMTNANKEKHFLKE---EKNKLSQELSTVATEKNKMAGELEVLRSQERrlKEKVANMEVALDKASLQF 820

                          410
                   ....*....|..
gi 767914037   558 LHV--VITSQEQ 567
Cdd:pfam15921  821 AECqdIIQRQEQ 832
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 206-556 5.41e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 62.35  E-value: 5.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  206 REAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKD----ATTLSLQTQMLRS 281
Cdd:TIGR04523  52 KEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNdkeqKNKLEVELNKLEK 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  282 SLEGTNA-------EIQRLKEDLEKADAlTFQTLNFLKSSLENtsiELHVLSRGLENANSEIQMLNASLetanTQAQLAN 354
Cdd:TIGR04523 132 QKKENKKnidkfltEIKKKEKELEKLNN-KYNDLKKQKEELEN---ELNLLEKEKLNIQKNIDKIKNKL----LKLELLL 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  355 SSLKNANAEIYVLrghLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNT-----NALNSQTQAF------------IK 417
Cdd:TIGR04523 204 SNLKKKIQKNKSL---ESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTqtqlnQLKDEQNKIKkqlsekqkeleqNN 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  418 SSFDNTSAEIQFLRGHL-----ERAGDEIHVLKRDL-----KMVTAQTQ--KANGRLDQTDTQIQVFKSEMENVNT---- 481
Cdd:TIGR04523 281 KKIKELEKQLNQLKSEIsdlnnQKEQDWNKELKSELknqekKLEEIQNQisQNNKIISQLNEQISQLKKELTNSESense 360

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767914037  482 LNAQIQVLNGHMKNASREIQTLKQGMKNasaLTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLK 556
Cdd:TIGR04523 361 KQRELEEKQNEIEKLKKENQSYKQEIKN---LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLK 432
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 204-571 1.17e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 1.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   204 FGREAEMRELIQtfkghmenssawvvEIQMLKCRVDNVNSQLQVLGDHLGNTNadiQMVKGVLKDATTLSLQTQMLRSSL 283
Cdd:TIGR02168  673 LERRREIEELEE--------------KIEELEEKIAELEKALAELRKELEELE---EELEQLRKELEELSRQISALRKDL 735

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   284 EGTNAEIQRLKEDLEKADaltfQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAE 363
Cdd:TIGR02168  736 ARLEAEVEQLEERIAQLS----KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   364 iyvlrghLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHV 443
Cdd:TIGR02168  812 -------LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS 884

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   444 LKRDLKmvtaqtqKANGRLDQTDTQIQvfksEMEN-VNTLNAQIQVLNGHMKNASREIQTLKQGMKN-ASALTSQTQM-- 519
Cdd:TIGR02168  885 LEEALA-------LLRSELEELSEELR----ELESkRSELRRELEELREKLAQLELRLEGLEVRIDNlQERLSEEYSLtl 953

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   520 ---------LDSNLQKASAEIQRLRGDLE-----NTKALTmEIQQEQSRLKTL----HVVITSQEQLQRT 571
Cdd:TIGR02168  954 eeaealenkIEDDEEEARRRLKRLENKIKelgpvNLAAIE-EYEELKERYDFLtaqkEDLTEAKETLEEA 1022
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 235-574 1.93e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.44  E-value: 1.93e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   235 KCRVDNVNSQLQVLGDHLGNTNAdiqMVKGVLKDattLSLQTQMLRSSLEgtnaEIQRLKEDleKADALTFQtLNFLKSS 314
Cdd:pfam15921  291 RSQANSIQSQLEIIQEQARNQNS---MYMRQLSD---LESTVSQLRSELR----EAKRMYED--KIEELEKQ-LVLANSE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   315 LENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNA-------NAEIYVLRGHLDSVND--------LRT 379
Cdd:pfam15921  358 LTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLwdrdtgnSITIDHLRRELDDRNMevqrlealLKA 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   380 QNQVLRNSLEGANAEIQGLKENLQNTNALNSQ---TQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLK---RDLKMVTA 453
Cdd:pfam15921  438 MKSECQGQMERQMAAIQGKNESLEKVSSLTAQlesTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQekeRAIEATNA 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   454 QTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKN-----------ASALTSQTQMLDS 522
Cdd:pfam15921  518 EITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENmtqlvgqhgrtAGAMQVEKAQLEK 597

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 767914037   523 NLQKASAEIQRLR--GDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSI 574
Cdd:pfam15921  598 EINDRRLELQEFKilKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDI 651
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 207-493 3.54e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.60  E-value: 3.54e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   207 EAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQmvkgvlkdatTLSLQTQMLRSSLEGT 286
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEIS----------RLEQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   287 NAEIQRLKEDLEKadaltfqtlnfLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYV 366
Cdd:TIGR02168  315 ERQLEELEAQLEE-----------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   367 LRghlDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNA-LNSQTQAFIKSSFDNTSAEI--------------QFLR 431
Cdd:TIGR02168  384 LR---SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQeIEELLKKLEEAELKELQAELeeleeeleelqeelERLE 460

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767914037   432 GHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHM 493
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIL 522
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 269-534 5.66e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.84  E-value: 5.66e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   269 ATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADAL----------TFQTLNFLKSSLEN-TSIELHVLSRGLENANSEIQ 337
Cdd:TIGR02169  225 GYELLKEKEALERQKEAIERQLASLEEELEKLTEEiselekrleeIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIA 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   338 MLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEganAEIQGLKENLqntNALNSQTQAfIK 417
Cdd:TIGR02169  305 SLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT---EEYAELKEEL---EDLRAELEE-VD 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   418 SSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEmenVNTLNAQIQVLNGHMKNAS 497
Cdd:TIGR02169  378 KEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAK---INELEEEKEDKALEIKKQE 454

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 767914037   498 REIQTLKQGMKNAS----ALTSQTQMLDSNLQKASAEIQRL 534
Cdd:TIGR02169  455 WKLEQLAADLSKYEqelyDLKEEYDRVEKELSKLQRELAEA 495
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 291-572 2.06e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 2.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 291 QRLKEDLEKADA-LTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETA-------NTQAQLANSSLKNANA 362
Cdd:COG1196  216 RELKEELKELEAeLLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELrleleelELELEEAQAEEYELLA 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 363 EIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQntnalnsqtqafikssfdntsAEIQFLRGHLERAGDEIH 442
Cdd:COG1196  296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE---------------------EELEELEEELEEAEEELE 354

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 443 VLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENvntLNAQIQVLNGHMKNASREIQTLKQgmkNASALTSQTQMLDS 522
Cdd:COG1196  355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLE---ALRAAAELAAQLEELEEAEEALLE---RLERLEEELEELEE 428

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 767914037 523 NLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQ 572
Cdd:COG1196  429 ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA 478
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
288-547 1.30e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 1.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 288 AEIQRLKEDLEKADALTFQTLNFLKS-----SLENTSIELHVLSRGLENANSEIQMLNAS-LETANTQAQLANSSLKNAN 361
Cdd:PRK03918 459 AELKRIEKELKEIEEKERKLRKELRElekvlKKESELIKLKELAEQLKELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLK 538

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 362 AEIYVLRGHLDSVNDLRtqnqvlrNSLEGANAEIQGLKENLQNtnaLNSQTQAFIKSSFDNTSAEIQFLR---------- 431
Cdd:PRK03918 539 GEIKSLKKELEKLEELK-------KKLAELEKKLDELEEELAE---LLKELEELGFESVEELEERLKELEpfyneylelk 608

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 432 ---GHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKS-----EMENVNT-----------LNAQIQVLNGH 492
Cdd:PRK03918 609 daeKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKkyseeEYEELREeylelsrelagLRAELEELEKR 688

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 767914037 493 MKNASREIQTLKQGMKNasalTSQTQMLDSNLQKASAEIQRLRGDLENTKALTME 547
Cdd:PRK03918 689 REEIKKTLEKLKEELEE----REKAKKELEKLEKALERVEELREKVKKYKALLKE 739
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
388-574 2.61e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 46.82  E-value: 2.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 388 LEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDT 467
Cdd:COG4372    8 VGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNE 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 468 QIQvfkSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKN----ASALTSQTQMLDSNLQKASAEIQRLRGDLENTKA 543
Cdd:COG4372   88 QLQ---AAQAELAQAQEELESLQEEAEELQEELEELQKERQDleqqRKQLEAQIAELQSEIAEREEELKELEEQLESLQE 164

                        170       180       190
                 ....*....|....*....|....*....|.
gi 767914037 544 LTMEIQQEQSRLKTLHVVITSQEQLQRTQSI 574
Cdd:COG4372  165 ELAALEQELQALSEAEAEQALDELLKEANRN 195
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 268-556 3.42e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.02  E-value: 3.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  268 DATTLSLQtQMLRSslegtnaEIQRLKEDLEKADALTFQtlnflkssLENTSIELHVLSRGLENANSEIQML------NA 341
Cdd:pfam05483 355 EATTCSLE-ELLRT-------EQQRLEKNEDQLKIITME--------LQKKSSELEEMTKFKNNKEVELEELkkilaeDE 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  342 SLETANTQAQLANSSLKNANAE-IYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQtqafIKSSF 420
Cdd:pfam05483 419 KLLDEKKQFEKIAEELKGKEQElIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIE----LTAHC 494

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  421 DNTSAEIQFLrghLERAGDEIHVLKRdlkmvtaQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREI 500
Cdd:pfam05483 495 DKLLLENKEL---TQEASDMTLELKK-------HQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEV 564

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767914037  501 Q-TLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLK 556
Cdd:pfam05483 565 KcKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALK 621
PRK01156 PRK01156
chromosome segregation protein; Provisional
 261-566 3.44e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.82  E-value: 3.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 261 MVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADAltfqTLNFLKSSLENTSIELHVLSRGLENANSEIQMLN 340
Cdd:PRK01156 170 KLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEK----SHSITLKEIERLSIEYNNAMDDYNNLKSALNELS 245

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 341 ASLETAN--------TQAQLANSSLKNA-------------NAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLK 399
Cdd:PRK01156 246 SLEDMKNryeseiktAESDLSMELEKNNyykeleerhmkiiNDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYH 325

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 400 ENLQNTNALNSQTQAFI--KSSFDNTSAEIQFLRGH------------------------LERAGDEIhvlKRDLKMVTA 453
Cdd:PRK01156 326 AIIKKLSVLQKDYNDYIkkKSRYDDLNNQILELEGYemdynsylksieslkkkieeysknIERMSAFI---SEILKIQEI 402

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 454 QTQKANGRLDQTDTQIQVFKSEMENvntLNAQIQVLNGHMKNASREIQTLK-QGMKNASALTSQTQMLDSNLQKASAEIQ 532
Cdd:PRK01156 403 DPDAIKKELNEINVKLQDISSKVSS---LNQRIRALRENLDELSRNMEMLNgQSVCPVCGTTLGEEKSNHIINHYNEKKS 479

                        330       340       350
                 ....*....|....*....|....*....|....
gi 767914037 533 RLRGDLENTKALTMEIQQEQSRLKTLHVVITSQE 566
Cdd:PRK01156 480 RLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEE 513
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 205-558 5.85e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.21  E-value: 5.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   205 GREAEMRELIQTFKGHMENSSAwvvEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQM-------VKGVLKDATT----LS 273
Cdd:TIGR02169  674 AELQRLRERLEGLKRELSSLQS---ELRRIENRLDELSQELSDASRKIGEIEKEIEQleqeeekLKERLEELEEdlssLE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   274 LQTQMLRSSLEGTNAEIQRLKEDLEKadaltfqtlnfLKSSLENtsIELHVlsrglenANSEIQMLNASLETANTQAQLA 353
Cdd:TIGR02169  751 QEIENVKSELKELEARIEELEEDLHK-----------LEEALND--LEARL-------SHSRIPEIQAELSKLEEEVSRI 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   354 NSSLKNANAEIyvlrghldsvNDLrtqnQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGH 433
Cdd:TIGR02169  811 EARLREIEQKL----------NRL----TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA 876

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   434 LERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKsemENVNTLNAQIQVLNGHMKnasrEIQTLKQGMKNASAL 513
Cdd:TIGR02169  877 LRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR---KRLSELKAKLEALEEELS----EIEDPKGEDEEIPEE 949

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 767914037   514 TSQTQMLDSNLQKASAEIQRLrGDLeNTKALTmEIQQEQSRLKTL 558
Cdd:TIGR02169  950 ELSLEDVQAELQRVEEEIRAL-EPV-NMLAIQ-EYEEVLKRLDEL 991
46 PHA02562
endonuclease subunit; Provisional
 363-569 6.62e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.78  E-value: 6.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 363 EIYVLrGHLDSVN-----DLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERA 437
Cdd:PHA02562 161 DISVL-SEMDKLNkdkirELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEEL 239

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 438 GDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSE-------------MENVNTLNAQIQVLNGHMKNASREIQTLK 504
Cdd:PHA02562 240 TDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVikmyekggvcptcTQQISEGPDRITKIKDKLKELQHSLEKLD 319

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767914037 505 QGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQ-EQLQ 569
Cdd:PHA02562 320 TAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEElAKLQ 385
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
260-569 8.07e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 45.28  E-value: 8.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 260 QMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKAdaltfqtlnflKSSLENTSIELHVLSRGLENANSEIQML 339
Cdd:COG4372   31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQA-----------RSELEQLEEELEELNEQLQAAQAELAQA 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 340 NASLETANTQAQLANSSLKNANAEIYVLRghlDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNA-LNSQTQAFIKS 418
Cdd:COG4372  100 QEELESLQEEAEELQEELEELQKERQDLE---QQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEeLAALEQELQAL 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 419 SFDNTSAEIQflrgHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASR 498
Cdd:COG4372  177 SEAEAEQALD----ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELL 252

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767914037 499 EIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQ 569
Cdd:COG4372  253 EEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLE 323
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 279-556 9.25e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.42  E-value: 9.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   279 LRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSS---------LENTSIELHVLSRGLENANSEIQM--LNASLETAN 347
Cdd:TIGR00606  749 LRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAkvcltdvtiMERFQMELKDVERKIAQQAAKLQGsdLDRTVQQVN 828

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   348 TQAQLANSSLKNANAEIYVLRghlDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKssfdntsaEI 427
Cdd:TIGR00606  829 QEKQEKQHELDTVVSKIELNR---KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELST--------EV 897

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   428 QFLRGHLERAGDEIHVLKRDLKMvtaqtqkangrlDQTDTQIQVFKSEMEN------VNTLNAQIQVLNGHMKNASREIQ 501
Cdd:TIGR00606  898 QSLIREIKDAKEQDSPLETFLEK------------DQQEKEELISSKETSNkkaqdkVNDIKEKVKNIHGYMKDIENKIQ 965

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   502 T-----LKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLK 556
Cdd:TIGR00606  966 DgkddyLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRK 1025
46 PHA02562
endonuclease subunit; Provisional
 332-509 1.56e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 1.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 332 ANSEIQMLNASLETANTQAQLANSSLKNANAeiyvlrghLDSVNDLRTQNQV--LRNSLEGANAEIQGLKENLQN----- 404
Cdd:PHA02562 179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRK--------KNGENIARKQNKYdeLVEEAKTIKAEIEELTDELLNlvmdi 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 405 ---TNALN--SQTQAFIKSSFDNTSAEIQFLRGH----------------LERAGDEIHVLKRDLKMVTAQTQKANGRLD 463
Cdd:PHA02562 251 edpSAALNklNTAAAKIKSKIEQFQKVIKMYEKGgvcptctqqisegpdrITKIKDKLKELQHSLEKLDTAIDELEEIMD 330

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 767914037 464 QTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKN 509
Cdd:PHA02562 331 EFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVD 376
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
269-532 1.93e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 269 ATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADA--LTFQTLNflksslentsielhvlsrGLENANSEIQMLNASLETA 346
Cdd:COG3206  163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAalEEFRQKN------------------GLVDLSEEAKLLLQQLSEL 224

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 347 NTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQvlrnslegANAEIQGLKENLQNTNAlnsqTQAFIKSSFDNTSAE 426
Cdd:COG3206  225 ESQLAEARAELAEAEARLAALRAQLGSGPDALPELL--------QSPVIQQLRAQLAELEA----ELAELSARYTPNHPD 292

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 427 IQFLRghleragDEIHVLKRDLKmvtaqtQKANGRLDQTDTQIQVFKSEmenVNTLNAQIQVLNGHMKNASREIQTLKQG 506
Cdd:COG3206  293 VIALR-------AQIAALRAQLQ------QEAQRILASLEAELEALQAR---EASLQAQLAQLEARLAELPELEAELRRL 356

                        250       260
                 ....*....|....*....|....*.
gi 767914037 507 MKNASALTSQTQMLDSNLQKASAEIQ 532
Cdd:COG3206  357 EREVEVARELYESLLQRLEEARLAEA 382
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 410-571 6.94e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 6.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 410 SQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNT----LNAQ 485
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKeiaeLRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 486 IQVLNGHMKNASREIQTLKQ--------GMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKT 557
Cdd:COG4942   99 LEAQKEELAELLRALYRLGRqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                        170
                 ....*....|....
gi 767914037 558 LhvvITSQEQLQRT 571
Cdd:COG4942  179 L---LAELEEERAA 189
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 230-487 7.87e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 7.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  230 EIQMLKCRVDNVNSQLQvlgdHLGNTNADIQM-VKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKED-------LEKAD 301
Cdd:TIGR04523 385 EIKNLESQINDLESKIQ----NQEKLNQQKDEqIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQdsvkeliIKNLD 460

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  302 ALTFQ----------TLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHL 371
Cdd:TIGR04523 461 NTRESletqlkvlsrSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKI 540

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  372 DSVND-LRTQNQVLRNSL-----EGANAEIQGLKENlqNTNALNSQTQAFIKssFDNTSAEIQFLRGHLERAGDEIHVLK 445
Cdd:TIGR04523 541 SDLEDeLNKDDFELKKENlekeiDEKNKEIEELKQT--QKSLKKKQEEKQEL--IDQKEKEKKDLIKEIEEKEKKISSLE 616

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 767914037  446 RDLKmvtaQTQKANGRLdqtDTQIQVFKSEMENVNTLNAQIQ 487
Cdd:TIGR04523 617 KELE----KAKKENEKL---SSIIKNIKSKKNKLKQEVKQIK 651
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
270-478 8.05e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.81  E-value: 8.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 270 TTLSLQTQMLRSSLEGTNAEIQRLKEDLEKAdaltfqtlnflKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQ 349
Cdd:COG4372   27 AALSEQLRKALFELDKLQEELEQLREELEQA-----------REELEQLEEELEQARSELEQLEEELEELNEQLQAAQAE 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 350 AQLANSSLKNANAEIYVLRghlDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQtqafIKSSFDNTSAEIQF 429
Cdd:COG4372   96 LAQAQEELESLQEEAEELQ---EELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKE----LEEQLESLQEELAA 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 767914037 430 LRGHLERAgdEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMEN 478
Cdd:COG4372  169 LEQELQAL--SEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRE 215
PRK11281 PRK11281
mechanosensitive channel MscK;
257-430 8.69e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 8.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  257 ADIQMVKgvlKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNF--LKSSLENTSIELHVLSRGLENANS 334
Cdd:PRK11281   73 DKIDRQK---EETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLrqLESRLAQTLDQLQNAQNDLAEYNS 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  335 EIQMLN-------ASLETANTQAQLANSSLKNANAEIYVLRGhlDSVNDLRTQNQVLrnslegaNAEIQGLKENLQNtna 407
Cdd:PRK11281  150 QLVSLQtqperaqAALYANSQRLQQIRNLLKGGKVGGKALRP--SQRVLLQAEQALL-------NAQNDLQRKSLEG--- 217

                         170       180
                  ....*....|....*....|...
gi 767914037  408 lNSQTQAFIKSSFDNTSAEIQFL 430
Cdd:PRK11281  218 -NTQLQDLLQKQRDYLTARIQRL 239
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 407-573 9.07e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 9.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 407 ALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMEnvnTLNAQI 486
Cdd:COG3883    5 ALAAPTPAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIA---EAEAEI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 487 QVLNGHMKNASREIQtlKQGM-----------KNASALTSQTQMLD---SNLQKASAEIQRLRGDLENTKALTMEIQQEQ 552
Cdd:COG3883   82 EERREELGERARALY--RSGGsvsyldvllgsESFSDFLDRLSALSkiaDADADLLEELKADKAELEAKKAELEAKLAEL 159

                        170       180
                 ....*....|....*....|.
gi 767914037 553 SRLKTLhvVITSQEQLQRTQS 573
Cdd:COG3883  160 EALKAE--LEAAKAELEAQQA 178
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
359-556 9.47e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 9.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 359 NANAEIYVLRghldsvnDLRTQNQVLRNSLEGANAEIQGLKENLQNT-NALnsqtQAF-IKSSFDNTSAEIQFLRGHLER 436
Cdd:COG3206  155 NALAEAYLEQ-------NLELRREEARKALEFLEEQLPELRKELEEAeAAL----EEFrQKNGLVDLSEEAKLLLQQLSE 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 437 AGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQI------QVFKSEMENVNTLNAQIQVL-----NGH--MKNASREIQTL 503
Cdd:COG3206  224 LESQLAEARAELAEAEARLAALRAQLGSGPDALpellqsPVIQQLRAQLAELEAELAELsarytPNHpdVIALRAQIAAL 303

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767914037 504 KQGMKN-----ASALTSQTQMLDSNLQKASAEIQRLRGDLENTKaltmEIQQEQSRLK 556
Cdd:COG3206  304 RAQLQQeaqriLASLEAELEALQAREASLQAQLAQLEARLAELP----ELEAELRRLE 357
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 428-576 1.34e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 1.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   428 QFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGH-MKNASREIQTLKQG 506
Cdd:smart00787 140 KLLEGLKEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTeLDRAKEKLKKLLQE 219

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767914037   507 M----KNASALTSQTQMLDSNLQKASAEIQRLRGDLentkaltMEIQQ--EQSRLKTLHVVITSQEQLQRTQSISG 576
Cdd:smart00787 220 ImikvKKLEELEEELQELESKIEDLTNKKSELNTEI-------AEAEKklEQCRGFTFKEIEKLKEQLKLLQSLTG 288
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 275-558 1.45e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.75  E-value: 1.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   275 QTQMLRSSLEGTNAEIQ----RLKEDLEKADALTFQTL--NFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANT 348
Cdd:pfam12128  420 LESELREQLEAGKLEFNeeeyRLKSRLGELKLRLNQATatPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARK 499

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   349 QAQLANSSLKNANAEIYVLRGHLDSVND-LRTQNQVLrnsLEGANAEIQGLKENLQNTNAlnsqTQAFIKSSFDNTSAEI 427
Cdd:pfam12128  500 RRDQASEALRQASRRLEERQSALDELELqLFPQAGTL---LHFLRKEAPDWEQSIGKVIS----PELLHRTDLDPEVWDG 572

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   428 QfLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQvfkSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGM 507
Cdd:pfam12128  573 S-VGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQ---SAREKQAAAEEQLVQANGELEKASREETFARTAL 648

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 767914037   508 KNAsaltsqtqmlDSNLQKASAEIQRLRgdLENTKALTMEIQQEQSRLKTL 558
Cdd:pfam12128  649 KNA----------RLDLRRLFDEKQSEK--DKKNKALAERKDSANERLNSL 687
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 431-573 1.67e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 1.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037   431 RGHLERAGDEIHVLKRDLKMVTAQTQKA------NGRLDQTDTQIQV--FKSEMENVNTLNAQIQVLNGHMKNASREIQt 502
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKSLERQAEKAerykelKAELRELELALLVlrLEELREELEELQEELKEAEEELEELTAELQ- 263

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767914037   503 lkqgmknasALTSQTQMLDSNLQKASAEIQRLRGDLENTKA----LTMEIQQEQSRLKTLHVVITS-QEQLQRTQS 573
Cdd:TIGR02168  264 ---------ELEEKLEELRLEVSELEEEIEELQKELYALANeisrLEQQKQILRERLANLERQLEElEAQLEELES 330
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
367-580 2.47e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 2.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  367 LRGHLDSVNDLRTQNQVLRNsLEGANAEIQGLKENLQNTNALNSQTQAFIKSsfdntsAEIQFLRGHLERAGDEIHVLKR 446
Cdd:COG4913   237 LERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAALRLWFAQ------RRLELLEAELEELRAELARLEA 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  447 DLKMVTAQTQKANGRLDQTDTQIQvfKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMK--------NASALTSQTQ 518
Cdd:COG4913   310 ELERLEARLDALREELDELEAQIR--GNGGDRLEQLEREIERLERELEERERRRARLEALLAalglplpaSAEEFAALRA 387

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767914037  519 MLDSNLQKASAEIQRLRGDLENTKAltmEIQQEQSRLKTLHVVITSqeqLQRTQS-ISGRVHK 580
Cdd:COG4913   388 EAAALLEALEEELEALEEALAEAEA---ALRDLRRELRELEAEIAS---LERRKSnIPARLLA 444
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 230-425 3.72e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 39.81  E-value: 3.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 230 EIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDAttlslQTQM--LRSSLEGTNAEIQRLKEDLEKADALTFQ- 306
Cdd:COG3883   24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEAL-----QAEIdkLQAEIAEAEAEIEERREELGERARALYRs 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 307 --TLNFLKSSLENTSIE-----LHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRT 379
Cdd:COG3883   99 ggSVSYLDVLLGSESFSdfldrLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQA 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 767914037 380 QNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSA 425
Cdd:COG3883  179 EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 338-576 4.99e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.36  E-value: 4.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 338 MLNASLETANTQAQLANSSLKNANAEIYVLRGHLdsvNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIK 417
Cdd:COG4942   10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKEL---AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 418 ssfdNTSAEIQFLRGHLERagdeihvLKRDLK--MVTAQTQKANGRL---------DQTDTQIQVFKS----EMENVNTL 482
Cdd:COG4942   87 ----ELEKEIAELRAELEA-------QKEELAelLRALYRLGRQPPLalllspedfLDAVRRLQYLKYlapaRREQAEEL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 483 NAQIQVLNGHMKNASREIQTLKQGMKnasALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVI 562
Cdd:COG4942  156 RADLAELAALRAELEAERAELEALLA---ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232

                        250
                 ....*....|....
gi 767914037 563 TSQEQLQRTQSISG 576
Cdd:COG4942  233 EAEAAAAAERTPAA 246
mukB PRK04863
chromosome partition protein MukB;
315-569 6.67e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 39.56  E-value: 6.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  315 LENTSIELHVLSRGLENANSEIQMLNASLETANtqaQLANSSLKNA-----NAEIYVL---RGHLD-SVNDLRTQNQVLR 385
Cdd:PRK04863  788 IEQLRAEREELAERYATLSFDVQKLQRLHQAFS---RFIGSHLAVAfeadpEAELRQLnrrRVELErALADHESQEQQQR 864

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  386 NSLEGANAEIQGLKENLQNTNALnsqtqafikssFDNT-SAEIQFLRGHLERAgdeiHVLKRDLkmvtaqtQKANGRLDQ 464
Cdd:PRK04863  865 SQLEQAKEGLSALNRLLPRLNLL-----------ADETlADRVEEIREQLDEA----EEAKRFV-------QQHGNALAQ 922

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037  465 TDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALT-SQTQMLdsnLQKASAEIQRLRGDLEntka 543
Cdd:PRK04863  923 LEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFSyEDAAEM---LAKNSDLNEKLRQRLE---- 995

                         250       260
                  ....*....|....*....|....*.
gi 767914037  544 ltmEIQQEQSRLKTLHVviTSQEQLQ 569
Cdd:PRK04863  996 ---QAEQERTRAREQLR--QAQAQLA 1016
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
393-580 6.94e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 39.37  E-value: 6.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 393 AEIQGLKENLQNTNALNSQTQAFIKSsFDNTSAEIQFLRGHLERAGDEIHVLKR--DLKMVTAQTQKANGRLDQTDTQIQ 470
Cdd:COG4717   71 KELKELEEELKEAEEKEEEYAELQEE-LEELEEELEELEAELEELREELEKLEKllQLLPLYQELEALEAELAELPERLE 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767914037 471 VFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASAltsqtqmldSNLQKASAEIQRLRGDLENTKAltmEIQQ 550
Cdd:COG4717  150 ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---------EELQDLAEELEELQQRLAELEE---ELEE 217

                        170       180       190
                 ....*....|....*....|....*....|
gi 767914037 551 EQSRLKTLHVVITSQEQLQRTQSISGRVHK 580
Cdd:COG4717  218 AQEELEELEEELEQLENELEAAALEERLKE 247
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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