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Conserved domains on  [gi|1034639196|ref|XP_011530118|]
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cilia- and flagella-associated protein 299 isoform X6 [Homo sapiens]

Protein Classification

CFAP299 family protein( domain architecture ID 141109)

CFAP299 family protein is a DUF4464 domain-containing protein; similar to Homo sapiens Cilia- and flagella-associated protein 299 (CFAP299) that may be involved in spermatogenesis

Gene Ontology:  GO:0005737

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4464 super family cl20648
Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins ...
 31-129 1.20e-47

Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins in this family are typically between 224 and 241 amino acids in length. There is a conserved YID sequence motif.


The actual alignment was detected with superfamily member pfam14713:

Pssm-ID: 464276  Cd Length: 229  Bit Score: 153.48  E-value: 1.20e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034639196  31 IVTQFNAYEDFLDSQITTVDLYYLEDETLARQLVELGYRGTGERVKREDFEARKAAIEIARLAERAQQKTLTSAGKDL-Q 109
Cdd:pfam14713   1 SLLEFNTYEDYLDSFITPEDLRYLENEELARQLVELGYRGTGEVLTREEFEARKKAAEEALLPKGLKPKQLFSAGLDLsK 80

                          90       100
                  ....*....|....*....|
gi 1034639196 110 DNFLTALAMREEDNRSGKLS 129
Cdd:pfam14713  81 DPFLQALAEREEPNRNGKLS 100
 
Name Accession Description Interval E-value
DUF4464 pfam14713
Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins ...
 31-129 1.20e-47

Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins in this family are typically between 224 and 241 amino acids in length. There is a conserved YID sequence motif.


Pssm-ID: 464276  Cd Length: 229  Bit Score: 153.48  E-value: 1.20e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034639196  31 IVTQFNAYEDFLDSQITTVDLYYLEDETLARQLVELGYRGTGERVKREDFEARKAAIEIARLAERAQQKTLTSAGKDL-Q 109
Cdd:pfam14713   1 SLLEFNTYEDYLDSFITPEDLRYLENEELARQLVELGYRGTGEVLTREEFEARKKAAEEALLPKGLKPKQLFSAGLDLsK 80

                          90       100
                  ....*....|....*....|
gi 1034639196 110 DNFLTALAMREEDNRSGKLS 129
Cdd:pfam14713  81 DPFLQALAEREEPNRNGKLS 100
 
Name Accession Description Interval E-value
DUF4464 pfam14713
Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins ...
 31-129 1.20e-47

Domain of unknown function (DUF4464); This family of proteins is found in eukaryotes. Proteins in this family are typically between 224 and 241 amino acids in length. There is a conserved YID sequence motif.


Pssm-ID: 464276  Cd Length: 229  Bit Score: 153.48  E-value: 1.20e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034639196  31 IVTQFNAYEDFLDSQITTVDLYYLEDETLARQLVELGYRGTGERVKREDFEARKAAIEIARLAERAQQKTLTSAGKDL-Q 109
Cdd:pfam14713   1 SLLEFNTYEDYLDSFITPEDLRYLENEELARQLVELGYRGTGEVLTREEFEARKKAAEEALLPKGLKPKQLFSAGLDLsK 80

                          90       100
                  ....*....|....*....|
gi 1034639196 110 DNFLTALAMREEDNRSGKLS 129
Cdd:pfam14713  81 DPFLQALAEREEPNRNGKLS 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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