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Conserved domains on  [gi|768014524|ref|XP_011527680|]
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protein sel-1 homolog 2 isoform X8 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11434433)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
170-364 1.66e-45

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 160.86  E-value: 1.66e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 170 WDIYQYYKFLAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKY 249
Cdd:COG0790   48 AAAAAAAAAAAAAGGAEAQYNLGLMYAEGR-GVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEW 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 250 FSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 329
Cdd:COG0790  126 YEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQG 205

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 768014524 330 QPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 364
Cdd:COG0790  206 DADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
12-219 7.21e-18

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 83.05  E-value: 7.21e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524  12 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 91
Cdd:COG0790   80 PKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524  92 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVadyiadtfeksegvpvekvrlterpenlssnseildwd 171
Cdd:COG0790  160 EWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKA-------------------------------------- 201

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 768014524 172 iyqyykflAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKA 219
Cdd:COG0790  202 --------AEQGDADAQYNLGRLYLNGE-GVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
386-508 2.43e-12

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 66.88  E-value: 2.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 386 SLVQYALLAEMGYEVAQSNSAFILESKKANILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATH 465
Cdd:COG0790   10 AAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEW 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 768014524 466 YSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 508
Cdd:COG0790   90 FEKAAEQ-GDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAE 131
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
170-364 1.66e-45

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 160.86  E-value: 1.66e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 170 WDIYQYYKFLAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKY 249
Cdd:COG0790   48 AAAAAAAAAAAAAGGAEAQYNLGLMYAEGR-GVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEW 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 250 FSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 329
Cdd:COG0790  126 YEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQG 205

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 768014524 330 QPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 364
Cdd:COG0790  206 DADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
12-219 7.21e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 83.05  E-value: 7.21e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524  12 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 91
Cdd:COG0790   80 PKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524  92 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVadyiadtfeksegvpvekvrlterpenlssnseildwd 171
Cdd:COG0790  160 EWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKA-------------------------------------- 201

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 768014524 172 iyqyykflAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKA 219
Cdd:COG0790  202 --------AEQGDADAQYNLGRLYLNGE-GVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
386-508 2.43e-12

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 66.88  E-value: 2.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 386 SLVQYALLAEMGYEVAQSNSAFILESKKANILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATH 465
Cdd:COG0790   10 AAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEW 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 768014524 466 YSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 508
Cdd:COG0790   90 FEKAAEQ-GDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAE 131
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 476-508 3.72e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 43.70  E-value: 3.72e-06
                           10        20        30
                   ....*....|....*....|....*....|...
gi 768014524   476 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 508
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 476-508 4.13e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 43.66  E-value: 4.13e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 768014524  476 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 508
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAE 33
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 295-329 5.09e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 43.32  E-value: 5.09e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 768014524   295 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 329
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 259-293 1.80e-05

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 41.74  E-value: 1.80e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 768014524  259 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 293
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
170-364 1.66e-45

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 160.86  E-value: 1.66e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 170 WDIYQYYKFLAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKY 249
Cdd:COG0790   48 AAAAAAAAAAAAAGGAEAQYNLGLMYAEGR-GVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEW 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 250 FSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 329
Cdd:COG0790  126 YEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQG 205

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 768014524 330 QPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 364
Cdd:COG0790  206 DADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
204-366 3.24e-37

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 138.14  E-value: 3.24e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 204 QDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEAL 283
Cdd:COG0790   45 AGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRG-VPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKAL 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 284 KYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCE 363
Cdd:COG0790  124 EWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAE 203


                 ...
gi 768014524 364 LGH 366
Cdd:COG0790  204 QGD 206
TPR COG0790
TPR repeat [General function prediction only];
214-508 2.55e-35

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 133.13  E-value: 2.55e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 214 LKAAKAGSANAMAFIGKMYLEGNAAVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 293
Cdd:COG0790   18 LAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQG 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 294 WPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVELYKgvcelghwaekflt 373
Cdd:COG0790   98 DAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYR-------------- 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 374 ayfaykdgdidsslvqyallaemgyevaqsnsafileskkanilekekmypmalllwnRAAIQGNAFARVKIGDYHYYGY 453
Cdd:COG0790  164 ----------------------------------------------------------KAAEQGDADAQYNLGVLYENGR 185

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 768014524 454 GTKKDYQTAATHYSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 508
Cdd:COG0790  186 GVPKDPAKALEWYRKAAEQ-GDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAE 239
TPR COG0790
TPR repeat [General function prediction only];
16-325 5.03e-31

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 120.80  E-value: 5.03e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524  16 EEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKALIYYT 95
Cdd:COG0790   12 AAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFE 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524  96 FGSAGGNMMSQMILGYRYLSGinvlqncevalsyykkvadyiadtfeksegvpvekvrlterpenlssnseildwdiyqy 175
Cdd:COG0790   92 KAAEQGDAEAQYNLGLMYEEG----------------------------------------------------------- 112

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 176 ykflaergdvqiqvslgqlhligrKGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNaAVPQNNATAFKYFSMAAS 255
Cdd:COG0790  113 ------------------------LGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGE-GVPKDPAKAAEWYRKAAE 167

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 256 KGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLA 325
Cdd:COG0790  168 QGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKA 237
TPR COG0790
TPR repeat [General function prediction only];
12-219 7.21e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 83.05  E-value: 7.21e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524  12 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 91
Cdd:COG0790   80 PKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524  92 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVadyiadtfeksegvpvekvrlterpenlssnseildwd 171
Cdd:COG0790  160 EWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKA-------------------------------------- 201

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 768014524 172 iyqyykflAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKA 219
Cdd:COG0790  202 --------AEQGDADAQYNLGRLYLNGE-GVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
386-508 2.43e-12

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 66.88  E-value: 2.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 386 SLVQYALLAEMGYEVAQSNSAFILESKKANILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATH 465
Cdd:COG0790   10 AAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEW 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 768014524 466 YSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 508
Cdd:COG0790   90 FEKAAEQ-GDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAE 131
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 476-508 3.72e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 43.70  E-value: 3.72e-06
                           10        20        30
                   ....*....|....*....|....*....|...
gi 768014524   476 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 508
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 476-508 4.13e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 43.66  E-value: 4.13e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 768014524  476 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 508
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAE 33
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 295-329 5.09e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 43.32  E-value: 5.09e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 768014524   295 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 329
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 259-293 7.83e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 42.93  E-value: 7.83e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 768014524   259 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 293
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 259-293 1.80e-05

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 41.74  E-value: 1.80e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 768014524  259 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 293
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
TPR COG0790
TPR repeat [General function prediction only];
419-508 1.24e-04

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 43.76  E-value: 1.24e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768014524 419 KEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATHYSIAANKYHNAQAMFNLAYMYEHGLGITKDIHL 498
Cdd:COG0790    6 AAAAAAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEK 85

                         90
                 ....*....|
gi 768014524 499 ARRLYDMAAQ 508
Cdd:COG0790   86 ALEWFEKAAE 95
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 331-366 2.12e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 38.69  E-value: 2.12e-04
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 768014524   331 PLAIYYLAKMYATGTGVVRSCRTAVELYKGVCELGH 366
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 295-329 4.33e-04

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 37.89  E-value: 4.33e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 768014524  295 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 329
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 222-258 5.97e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 34.84  E-value: 5.97e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 768014524   222 ANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGN 258
Cdd:smart00671   1 AEAQYNLGQMYEYGLG-VPKDLEKALEYYKKAAELGN 36
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 439-474 7.34e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 34.46  E-value: 7.34e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 768014524   439 AFARVKIGDYHYYGYGTKKDYQTAATHYSIAANKYH 474
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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