|
Name |
Accession |
Description |
Interval |
E-value |
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
690-1001 |
2.16e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 78.05 E-value: 2.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 690 EREKDDMETKLLHLEDVVRALEKHVDLRENDR---LEFHRLSEE-----NTLLKNDLGRVRQELEAAESTHDAQRKEIEV 761
Cdd:COG1196 178 ERKLEATEENLERLEDILGELERQLEPLERQAekaERYRELKEElkeleAELLLLKLRELEAELEELEAELEELEAELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 762 LKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRV 841
Cdd:COG1196 258 LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 842 ELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVR--LVPQDRVAELHRLLsLQGEQARRRLDAQR 919
Cdd:COG1196 338 ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEelLEALRAAAELAAQL-EELEEAEEALLERL 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 920 EEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLL 999
Cdd:COG1196 417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
|
..
gi 768013530 1000 EE 1001
Cdd:COG1196 497 LE 498
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
690-1014 |
3.20e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.86 E-value: 3.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 690 EREKDDMETKLLHLEDVVRALEKHVDLRENDR---LEFHRLSEE-----NTLLKNDLGRVRQELEAAESTHDAQRKEIEV 761
Cdd:TIGR02168 178 ERKLERTRENLDRLEDILNELERQLKSLERQAekaERYKELKAElreleLALLVLRLEELREELEELQEELKEAEEELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 762 LKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRV 841
Cdd:TIGR02168 258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 842 ELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRlvpqdRVAELhrllslqgEQARRRLDAQREE 921
Cdd:TIGR02168 338 ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS-----KVAQL--------ELQIASLNNEIER 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 922 HEKQLKATEERVEEAEMILKNMEMLLQEKvdKLKEQFEKNTKSDLLLKELYVENAHLVRALQatEEKQRGAEKQSRLLEE 1001
Cdd:TIGR02168 405 LEARLERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALE--ELREELEEAEQALDAA 480
|
330
....*....|...
gi 768013530 1002 KvRALNKLVSRIA 1014
Cdd:TIGR02168 481 E-RELAQLQARLD 492
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
689-1015 |
5.95e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.09 E-value: 5.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 689 LEREKDDMETKLLHLEDVVRALEKHVdlrENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEK 768
Cdd:TIGR02168 717 LRKELEELSRQISALRKDLARLEAEV---EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 769 ACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEevvrsgqQQSDQIQKLRVELEclnq 848
Cdd:TIGR02168 794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE-------ELSEDIESLAAEIE---- 862
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 849 ehqslqlpwsELTQTLEESQDQVQgAHLRLRQAQAQHLQEVRLVPQDRVAELHRLlslqgEQARRRLDAQREEHEKQLKA 928
Cdd:TIGR02168 863 ----------ELEELIEELESELE-ALLNERASLEEALALLRSELEELSEELREL-----ESKRSELRRELEELREKLAQ 926
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 929 TEERVEEAEMilknmemllqeKVDKLKEQFekntksdlllkelyveNAHLVRALQATEEKQRGAEKQSRLLEEKVRALNK 1008
Cdd:TIGR02168 927 LELRLEGLEV-----------RIDNLQERL----------------SEEYSLTLEEAEALENKIEDDEEEARRRLKRLEN 979
|
....*..
gi 768013530 1009 LVSRIAP 1015
Cdd:TIGR02168 980 KIKELGP 986
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
723-1006 |
3.66e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.85 E-value: 3.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 723 EFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQ-------NYKDQLSQLNVRVL 795
Cdd:TIGR02169 689 ELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSsleqeieNVKSELKELEARIE 768
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 796 QLgqEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAH 875
Cdd:TIGR02169 769 EL--EEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLK 846
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 876 LRLRQ-AQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKL 954
Cdd:TIGR02169 847 EQIKSiEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 768013530 955 KEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRgaekqsrlLEEKVRAL 1006
Cdd:TIGR02169 927 EALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQR--------VEEEIRAL 970
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
622-1014 |
5.17e-09 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 60.74 E-value: 5.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 622 RSWSRGTQEQASEQQARAEGALEPGCHkhsveVARRGSLPSHLQLADP-QGSWQEQLAAPEegetkiALEREKDDMETKL 700
Cdd:PRK04863 293 RELYTSRRQLAAEQYRLVEMARELAEL-----NEAESDLEQDYQAASDhLNLVQTALRQQE------KIERYQADLEELE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 701 LHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLkkDKEKACSEMEVLNRQN 780
Cdd:PRK04863 362 ERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQAL--ERAKQLCGLPDLTADN 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 781 -----QNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSdQIQKLR--VELECLNQEHQSL 853
Cdd:PRK04863 440 aedwlEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDV-ARELLRrlREQRHLAEQLQQL 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 854 QLPWSELTQTLEESQDQVQgahlRLRQAQAQHLQEVrlvpqDRVAELHRLLSLQGEQ------ARRRLDAQREEHEKQLK 927
Cdd:PRK04863 519 RMRLSELEQRLRQQQRAER----LLAEFCKRLGKNL-----DDEDELEQLQEELEARleslseSVSEARERRMALRQQLE 589
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 928 ATEERVEEAEmILKNMEMLLQEKVDKLKEQFEKNtksdlllkelyVENAHLVRAL-QATEEKQRGAEKQSRLLEEKVRAL 1006
Cdd:PRK04863 590 QLQARIQRLA-ARAPAWLAAQDALARLREQSGEE-----------FEDSQDVTEYmQQLLERERELTVERDELAARKQAL 657
|
....*...
gi 768013530 1007 NKLVSRIA 1014
Cdd:PRK04863 658 DEEIERLS 665
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
671-957 |
2.05e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.54 E-value: 2.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 671 GSWQEQLAAPEEGETKIA-LEREKDDMETKLLHLEDVVRALEKhvdLRENDRLEFHRLSEENTL-LKNDLGRVRQELEAA 748
Cdd:TIGR02169 230 KEKEALERQKEAIERQLAsLEEELEKLTEEISELEKRLEEIEQ---LLEELNKKIKDLGEEEQLrVKEKIGELEAEIASL 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 749 ESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEhrvtiqmLTQSLEEVVRS 828
Cdd:TIGR02169 307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELED-------LRAELEEVDKE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 829 GQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQH--LQEVRLVPQDRVAELhrllsl 906
Cdd:TIGR02169 380 FAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIneLEEEKEDKALEIKKQ------ 453
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 768013530 907 qgEQARRRLDAQREEHEKQLKATEERVEEAEMILKNmemlLQEKVDKLKEQ 957
Cdd:TIGR02169 454 --EWKLEQLAADLSKYEQELYDLKEEYDRVEKELSK----LQRELAEAEAQ 498
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
696-1013 |
2.32e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 58.11 E-value: 2.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 696 METKLLHLEDVVRALEKHVDLrENDRL------------EFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRK------ 757
Cdd:TIGR04523 216 LESQISELKKQNNQLKDNIEK-KQQEInektteisntqtQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKqlnqlk 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 758 -EIEVLKKDKEKACS------------EMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEE 824
Cdd:TIGR04523 295 sEISDLNNQKEQDWNkelkselknqekKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEK 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 825 VVRSGQQQSDQIQKLRVELECLNQEHQSLQlpwsELTQTLEESQDQVQGAHLRLRQaQAQHLQEVRLVPQDRVAELHRLL 904
Cdd:TIGR04523 375 LKKENQSYKQEIKNLESQINDLESKIQNQE----KLNQQKDEQIKKLQQEKELLEK-EIERLKETIIKNNSEIKDLTNQD 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 905 SlQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELyvenahlvralqa 984
Cdd:TIGR04523 450 S-VKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDL------------- 515
|
330 340
....*....|....*....|....*....
gi 768013530 985 teekqrgaEKQSRLLEEKVRALNKLVSRI 1013
Cdd:TIGR04523 516 --------TKKISSLKEKIEKLESEKKEK 536
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
699-1004 |
6.78e-08 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 56.67 E-value: 6.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 699 KLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRvRQELEAAESTHDAQRKEIEVLKKDKEKACSEmevlnR 778
Cdd:pfam17380 273 QLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVER-RRKLEEAEKARQAEMDRQAAIYAEQERMAME-----R 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 779 QNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRsgqQQSDQIQKLRVELEclnQEHQSLQLPWS 858
Cdd:pfam17380 347 ERELERIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVR---QELEAARKVKILEE---ERQRKIQQQKV 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 859 ELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEER-VEEAE 937
Cdd:pfam17380 421 EMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRkILEKE 500
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768013530 938 MILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVR 1004
Cdd:pfam17380 501 LEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSR 567
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
734-1013 |
7.99e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 56.57 E-value: 7.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 734 LKNDLGRVRQELEAAESTHDAQRKEIEvlkkdkEKAcSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRV 813
Cdd:TIGR04523 340 LNEQISQLKKELTNSESENSEKQRELE------EKQ-NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDE 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 814 TIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQ---GAHLRLRQAQAQHLQEVR 890
Cdd:TIGR04523 413 QIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKvlsRSINKIKQNLEQKQKELK 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 891 LVPQD-------------RVAELHRLLSlQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEML-----LQEKVD 952
Cdd:TIGR04523 493 SKEKElkklneekkeleeKVKDLTKKIS-SLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEkeideKNKEIE 571
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768013530 953 KLKEQFE----KNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRI 1013
Cdd:TIGR04523 572 ELKQTQKslkkKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNI 636
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
681-921 |
9.69e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.48 E-value: 9.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 681 EEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFH-----------RLSEENTLLKNDLGRVRQELEAAE 749
Cdd:COG1196 250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLaelarleqdiaRLEERRRELEERLEELEEELAELE 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 750 STHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSG 829
Cdd:COG1196 330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 830 QQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGE 909
Cdd:COG1196 410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
|
250
....*....|..
gi 768013530 910 QARRRLDAQREE 921
Cdd:COG1196 490 AARLLLLLEAEA 501
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
720-972 |
8.74e-07 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 52.71 E-value: 8.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 720 DRLEFHRLSEENTLLKNDLGRVRQELeaaeSTHDAQRKEIEvlkkdkEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQ 799
Cdd:PHA02562 158 DLLDISVLSEMDKLNKDKIRELNQQI----QTLDMKIDHIQ------QQIKTYNKNIEEQRKKNGENIARKQNKYDELVE 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 800 EASTHQAQNEEhrvtiqmLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQlpwSEL------------TQTLEES 867
Cdd:PHA02562 228 EAKTIKAEIEE-------LTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQ---KVIkmyekggvcptcTQQISEG 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 868 QDQVQGAHLRLRQAQAQHLQEvrlvpQDRVAELHRLLSLQGEQARRRLDAQRE-EHEKQLKATEerVEEAEMILKNMEML 946
Cdd:PHA02562 298 PDRITKIKDKLKELQHSLEKL-----DTAIDELEEIMDEFNEQSKKLLELKNKiSTNKQSLITL--VDKAKKVKAAIEEL 370
|
250 260 270
....*....|....*....|....*....|....
gi 768013530 947 LQEKVD------KLKEQFEK--NTKSDlLLKELY 972
Cdd:PHA02562 371 QAEFVDnaeelaKLQDELDKivKTKSE-LVKEKY 403
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
721-984 |
2.16e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 51.67 E-value: 2.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 721 RLEFHRLSEENTLLKNDLG--RVRQELEAAESTHDAQ-----------RKEIEVLKK---DKEKACSEMEVLNRQNQNYK 784
Cdd:pfam05557 6 ESKARLSQLQNEKKQMELEhkRARIELEKKASALKRQldresdrnqelQKRIRLLEKreaEAEEALREQAELNRLKKKYL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 785 DQLSQLnvrvlqlgqeASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQ-- 862
Cdd:pfam05557 86 EALNKK----------LNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQlr 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 863 -TLEESQDQVQGAHLRLR------QAQAQHLQEVRlvpqDRVAELHRLLSLQGEQARRRldaqreEHEKQLKATEERVEe 935
Cdd:pfam05557 156 qNLEKQQSSLAEAEQRIKelefeiQSQEQDSEIVK----NSKSELARIPELEKELERLR------EHNKHLNENIENKL- 224
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 768013530 936 aemilknmemLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQA 984
Cdd:pfam05557 225 ----------LLKEEVEDLKRKLEREEKYREEAATLELEKEKLEQELQS 263
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
734-963 |
2.90e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.92 E-value: 2.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 734 LKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHR- 812
Cdd:COG4942 25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKe 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 813 ------VTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQslqlpwsELTQTLEESQDQVQgahlRLRQAQAQHL 886
Cdd:COG4942 105 elaellRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARR-------EQAEELRADLAELA----ALRAELEAER 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768013530 887 QEVRLVPQDRVAELHRLLSLQGEQAR--RRLDAQREEHEKQLKATEERVEEaemilknmemlLQEKVDKLKEQFEKNTK 963
Cdd:COG4942 174 AELEALLAELEEERAALEALKAERQKllARLEKELAELAAELAELQQEAEE-----------LEALIARLEAEAAAAAE 241
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
742-936 |
9.91e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.99 E-value: 9.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 742 RQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQS 821
Cdd:COG4942 26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 822 LEEVVRSGQQQS--------------------------------DQIQKLRVELECLNQEHQSLQlpwsELTQTLEESQD 869
Cdd:COG4942 106 LAELLRALYRLGrqpplalllspedfldavrrlqylkylaparrEQAEELRADLAELAALRAELE----AERAELEALLA 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768013530 870 QVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQgeQARRRLDAQREEHEKQLKATEERVEEA 936
Cdd:COG4942 182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQ--QEAEELEALIARLEAEAAAAAERTPAA 246
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
754-1013 |
1.04e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 49.67 E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 754 AQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNvrvlqlgQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQS 833
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELE-------EELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 834 DQIQKLRVELECLNQEHQslqlpwsELTQTLEESQD--QVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQA 911
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIE-------ELEERLEEAEEelAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA 819
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 912 rRRLDAQREEHEKQLKATEERVEEAEMILKNME---MLLQEKVDKLKEQFEK-NTKSDLLLKELYVENAHLVRA---LQA 984
Cdd:TIGR02168 820 -ANLRERLESLERRIAATERRLEDLEEQIEELSediESLAAEIEELEELIEElESELEALLNERASLEEALALLrseLEE 898
|
250 260
....*....|....*....|....*....
gi 768013530 985 TEEKQRGAEKQSRLLEEKVRALNKLVSRI 1013
Cdd:TIGR02168 899 LSEELRELESKRSELRRELEELREKLAQL 927
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
785-1019 |
1.94e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 1.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 785 DQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTL 864
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 865 EESQDQVqGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDaQREEHEKQLKATEERVEEAEMILKNME 944
Cdd:COG4942 100 EAQKEEL-AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE-QAEELRADLAELAALRAELEAERAELE 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768013530 945 MLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALS 1019
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALK 252
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
600-974 |
2.02e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.98 E-value: 2.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 600 LRPAASCRGQAERLQAIQEE--RARSWSRGTQE--QASEQQARAEGALEPGCHKHSVEVARRGSLPShlQLADPQGSWQE 675
Cdd:PTZ00121 1410 LKKAAAAKKKADEAKKKAEEkkKADEAKKKAEEakKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK--KKAEEAKKADE 1487
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 676 QLAAPEEGETKIALEREKDDMETKLLHLE--------DVVRALEKHVDLRENDRLEFHRLSEE----NTLLKNDLGRVRQ 743
Cdd:PTZ00121 1488 AKKKAEEAKKKADEAKKAAEAKKKADEAKkaeeakkaDEAKKAEEAKKADEAKKAEEKKKADElkkaEELKKAEEKKKAE 1567
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 744 ELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQlsqlNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLE 823
Cdd:PTZ00121 1568 EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAE----EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA 1643
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 824 EVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQtlEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRL 903
Cdd:PTZ00121 1644 EEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKK--AEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEEL 1721
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768013530 904 LSLQGEQARRRLDAQREEHEKQLKATEERVEEAEmilknmemllQEKVDKLKEQFEKNTKSDLLLKELYVE 974
Cdd:PTZ00121 1722 KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE----------KKKIAHLKKEEEKKAEEIRKEKEAVIE 1782
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
675-1004 |
2.29e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.53 E-value: 2.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 675 EQLAAPEEGETKIALEREK-DDMETKLLHLEDVVRALEKHVDLRENDR---LEFHRLSE-----ENTLLKNDLGRVRQEL 745
Cdd:TIGR02169 160 DEIAGVAEFDRKKEKALEElEEVEENIERLDLIIDEKRQQLERLRRERekaERYQALLKekreyEGYELLKEKEALERQK 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 746 EAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRqnqnykdQLSQLNVRVLQLGQ-EASTHQAQNEEHRVTIQMLTQSLEE 824
Cdd:TIGR02169 240 EAIERQLASLEEELEKLTEEISELEKRLEEIEQ-------LLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAE 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 825 VVRSGQQQSDQIQKLRVELECLNQEHQ--------------SLQLPWSELTQTLEESQDQVQ---GAHLRLRQAQAQHLQ 887
Cdd:TIGR02169 313 KERELEDAEERLAKLEAEIDKLLAEIEelereieeerkrrdKLTEEYAELKEELEDLRAELEevdKEFAETRDELKDYRE 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 888 EVRLVpQDRVAELHRLLSLQGEQArRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLL 967
Cdd:TIGR02169 393 KLEKL-KREINELKRELDRLQEEL-QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470
|
330 340 350
....*....|....*....|....*....|....*..
gi 768013530 968 LKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVR 1004
Cdd:TIGR02169 471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVR 507
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
737-1009 |
2.83e-05 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 48.13 E-value: 2.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 737 DLGRVRQELEAAESTHDAQRKEI-EVLK----------------KDKEKACSEMEVLNRQNQNYKDQLSQ---------- 789
Cdd:PRK10929 24 DEKQITQELEQAKAAKTPAQAEIvEALQsalnwleerkgsleraKQYQQVIDNFPKLSAELRQQLNNERDeprsvppnms 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 790 ---LNVRVLQLGQE--ASTHQAQNEEHRvtIQMLTQSLEEVvrsGQQQSDqIQKLrvelecLNQEHQSLQLPWSELTqTL 864
Cdd:PRK10929 104 tdaLEQEILQVSSQllEKSRQAQQEQDR--AREISDSLSQL---PQQQTE-ARRQ------LNEIERRLQTLGTPNT-PL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 865 EESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRvAELHRLLSLQGEQARRRLDAQREEHEKQLKAteERVEEAEMILKNME 944
Cdd:PRK10929 171 AQAQLTALQAESAALKALVDELELAQLSANNR-QELARLRSELAKKRSQQLDAYLQALRNQLNS--QRQREAERALESTE 247
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768013530 945 MLLQEKVD---KLKEQFEKNtksdlllKELYVENAHLVRALQATEEKQRGAEKQSrlleEKVR-ALNKL 1009
Cdd:PRK10929 248 LLAEQSGDlpkSIVAQFKIN-------RELSQALNQQAQRMDLIASQQRQAASQT----LQVRqALNTL 305
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
735-1009 |
4.55e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.76 E-value: 4.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 735 KNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKAcsemevlnrqnQNYKDQLSQL-NVRVLQLGQEASTHQAQNEEHRV 813
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDEKRQQLERLRREREKA-----------ERYQALLKEKrEYEGYELLKEKEALERQKEAIER 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 814 TIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLN--------QEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQH 885
Cdd:TIGR02169 245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNkkikdlgeEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERL 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 886 lqevrlvpQDRVAELHRLLSlQGEQARRRLDAQReeheKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEK----N 961
Cdd:TIGR02169 325 --------AKLEAEIDKLLA-EIEELEREIEEER----KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDElkdyR 391
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 768013530 962 TKSDLLLKELYVENAHLVRALqatEEKQRGAEKQSRLLEEKVRALNKL 1009
Cdd:TIGR02169 392 EKLEKLKREINELKRELDRLQ---EELQRLSEELADLNAAIAGIEAKI 436
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
603-1011 |
7.72e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.04 E-value: 7.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 603 AASCRGQAERLQaiqeerarswsrgTQEQASEQQARAEGALEPgCHKHSVEvARRGSLPSHLQLA-----DPQGSWQEQL 677
Cdd:pfam15921 287 ASSARSQANSIQ-------------SQLEIIQEQARNQNSMYM-RQLSDLE-STVSQLRSELREAkrmyeDKIEELEKQL 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 678 AAPEEGETKIALEREKDDMETKllHLEDVVRALEKHVDLREND----RLEFHRLSEENTLLKNDLGRVRQELEaaESTHD 753
Cdd:pfam15921 352 VLANSELTEARTERDQFSQESG--NLDDQLQKLLADLHKREKElsleKEQNKRLWDRDTGNSITIDHLRRELD--DRNME 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 754 AQRKEiEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLG----------QEASTHQAQNEEHRVTIQMLTQSLE 823
Cdd:pfam15921 428 VQRLE-ALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLEstkemlrkvvEELTAKKMTLESSERTVSDLTASLQ 506
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 824 EVVRSGQQQSDQIQKLRVELECLNQEHQSLqlpwseltqtleesqdQVQGAHLRLRQAQAQHLQeVRLVPQDRVAELHR- 902
Cdd:pfam15921 507 EKERAIEATNAEITKLRSRVDLKLQELQHL----------------KNEGDHLRNVQTECEALK-LQMAEKDKVIEILRq 569
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 903 ----LLSLQGEQARRRLDAQREEHEKQLKATEERVEeaemiLKNMEMLLQEKVDKLKEQFEKntKSDLLLKELYVENAHL 978
Cdd:pfam15921 570 qienMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLE-----LQEFKILKDKKDAKIRELEAR--VSDLELEKVKLVNAGS 642
|
410 420 430
....*....|....*....|....*....|...
gi 768013530 979 VRALQATEEKQrgaeKQSRLLEEKVRALNKLVS 1011
Cdd:pfam15921 643 ERLRAVKDIKQ----ERDQLLNEVKTSRNELNS 671
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
685-1013 |
7.76e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 46.55 E-value: 7.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 685 TKIALErEKDDMETKLLhLEDVVRALEKhvDLRENDRLEFHRLSEentlLKNDlgrvRQELEAAESTHDAQRKEIEVLKK 764
Cdd:TIGR04523 106 SKINSE-IKNDKEQKNK-LEVELNKLEK--QKKENKKNIDKFLTE----IKKK----EKELEKLNNKYNDLKKQKEELEN 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 765 DKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLgqeasthQAQNEEHRvtiqMLTQSLEEVVRSGQQQSDQIQKLRVELE 844
Cdd:TIGR04523 174 ELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNL-------KKKIQKNK----SLESQISELKKQNNQLKDNIEKKQQEIN 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 845 CLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEvrlvpQDRVAELHRLLSLQGEQARRRLDaqrEEHEK 924
Cdd:TIGR04523 243 EKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKEL-----EKQLNQLKSEISDLNNQKEQDWN---KELKS 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 925 QLKATEERVEEAEMILKNMEmllqEKVDKLKEQFEKNTKSdllLKELYVENAHLVRALqatEEKQRGAEKQSRLLEEKVR 1004
Cdd:TIGR04523 315 ELKNQEKKLEEIQNQISQNN----KIISQLNEQISQLKKE---LTNSESENSEKQREL---EEKQNEIEKLKKENQSYKQ 384
|
....*....
gi 768013530 1005 ALNKLVSRI 1013
Cdd:TIGR04523 385 EIKNLESQI 393
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
609-1011 |
8.21e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 46.76 E-value: 8.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 609 QAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGchKHSVEVARRGSLPSHL---QLADPQGSWQEQLAAPEEGET 685
Cdd:pfam12128 600 EELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKA--SREETFARTALKNARLdlrRLFDEKQSEKDKKNKALAERK 677
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 686 KIALEREKD-DMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEvlkk 764
Cdd:pfam12128 678 DSANERLNSlEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALE---- 753
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 765 dkekacsemevlnrqnQNYKDQLSQLNV---RVLQLGQEasthqaqneehrvtIQMLTQSLEEVVRSGQQQSDQIQKLRv 841
Cdd:pfam12128 754 ----------------TWYKRDLASLGVdpdVIAKLKRE--------------IRTLERKIERIAVRRQEVLRYFDWYQ- 802
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 842 elECLNQEHQSLQLPWSELTQTLEESQDQV--QGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLL-SLQGEQARRRLDAQ 918
Cdd:pfam12128 803 --ETWLQRRPRLATQLSNIERAISELQQQLarLIADTKLRRAKLEMERKASEKQQVRLSENLRGLrCEMSKLATLKEDAN 880
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 919 REEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDL------LLKELYVENAHLVRALQATEEKQRGA 992
Cdd:pfam12128 881 SEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADHSGSGLaetwesLREEDHYQNDKGIRLLDYRKLVPYLE 960
|
410
....*....|....*....
gi 768013530 993 EKQSRLLEEKVRALNKLVS 1011
Cdd:pfam12128 961 QWFDVRVPQSIMVLREQVS 979
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
752-1017 |
1.14e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.21 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 752 HDAQRKEIEVLKKDKEKACS---EMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRS 828
Cdd:TIGR02169 659 SRAPRGGILFSRSEPAELQRlreRLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER 738
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 829 GQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQ-EVRLVPQDRVAELHRLLSLQ 907
Cdd:TIGR02169 739 LEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQaELSKLEEEVSRIEARLREIE 818
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 908 GEQARRRLDAQREEHEKQ-LKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSdllLKELYVENAHLVRALQATE 986
Cdd:TIGR02169 819 QKLNRLTLEKEYLEKEIQeLQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA---LRDLESRLGDLKKERDELE 895
|
250 260 270
....*....|....*....|....*....|.
gi 768013530 987 EKQRGAEKQSRLLEEKVRALNKLVSRIAPAA 1017
Cdd:TIGR02169 896 AQLRELERKIEELEAQIEKKRKRLSELKAKL 926
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
14-269 |
1.15e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.20 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 14 YRERL-SLLRSEVEAERELfwEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKL 92
Cdd:TIGR02168 307 LRERLaNLERQLEELEAQL--EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 93 QKDLefvlkdklepqsAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSwspdgrRRQLPglg 172
Cdd:TIGR02168 385 RSKV------------AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL------QAELE--- 443
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 173 pagisflgnsapvsiETELMMEQVKEHYQDLRTQLETKvnyyEREIAALKRNFEKERKDMEQARRRevsvLEGQKADLEE 252
Cdd:TIGR02168 444 ---------------ELEEELEELQEELERLEEALEEL----REELEEAEQALDAAERELAQLQAR----LDSLERLQEN 500
|
250
....*....|....*..
gi 768013530 253 LHEKSQEVIWGLQEQLQ 269
Cdd:TIGR02168 501 LEGFSEGVKALLKNQSG 517
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
607-1002 |
1.23e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 46.29 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 607 RGQAERLQAIQEERARSwsRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSlpSHLQLADPQGSWQEQLAAPEEGETK 686
Cdd:PTZ00121 1377 KKKADAAKKKAEEKKKA--DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKA--EEKKKADEAKKKAEEAKKADEAKKK 1452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 687 IALEREKDDMETKLLHLEDVVRALEKHVDLRENDrlEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQ-RKEIEVLKKD 765
Cdd:PTZ00121 1453 AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKAD--EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEeAKKADEAKKA 1530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 766 KEKACSEmEVLNRQNQNYKDQLSQLNvRVLQLGQEASTHQAQNEEHRVtiQMLTQSLEEVVRSGQQQSDQIQKLRVELEC 845
Cdd:PTZ00121 1531 EEAKKAD-EAKKAEEKKKADELKKAE-ELKKAEEKKKAEEAKKAEEDK--NMALRKAEEAKKAEEARIEEVMKLYEEEKK 1606
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 846 LNQEhqslQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAElhRLLSLQGEQARRRLDAQREEHEKQ 925
Cdd:PTZ00121 1607 MKAE----EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE--EENKIKAAEEAKKAEEDKKKAEEA 1680
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 768013530 926 LKATEERVEEAEMILKNMEMllQEKVDKLKEQF-EKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEK 1002
Cdd:PTZ00121 1681 KKAEEDEKKAAEALKKEAEE--AKKAEELKKKEaEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK 1756
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
820-1020 |
1.53e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.82 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 820 QSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEvrlvpQDRVAE 899
Cdd:TIGR02168 677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-----EERIAQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 900 LHRLLSLQGEQaRRRLDAQREEHEKQLKATEERVEEaemilknmemlLQEKVDKLKEQFEKNTKS-DLLLKELYVENAHL 978
Cdd:TIGR02168 752 LSKELTELEAE-IEELEERLEEAEEELAEAEAEIEE-----------LEAQIEQLKEELKALREAlDELRAELTLLNEEA 819
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 768013530 979 VRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV 1020
Cdd:TIGR02168 820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
609-1006 |
2.07e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.31 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 609 QAERLQAIQEERARSWSRGTQEQASEQQARAEGALEpgchKHSVEVARRGSLPSHLQLADPQGSWQEQLAApEEGETKIA 688
Cdd:COG1196 366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ----LEELEEAEEALLERLERLEEELEELEEALAE-LEEEEEEE 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 689 LEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEK 768
Cdd:COG1196 441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 769 ACSEMEVLNRQNQNYKDQ---------LSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKL 839
Cdd:COG1196 521 GLAGAVAVLIGVEAAYEAaleaalaaaLQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAA 600
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 840 RVELECLNQEHQSLQLP-----------------WSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRlvpqdRVAELHR 902
Cdd:COG1196 601 VDLVASDLREADARYYVlgdtllgrtlvaarleaALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR-----ELLAALL 675
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 903 LLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRAL 982
Cdd:COG1196 676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755
|
410 420
....*....|....*....|....
gi 768013530 983 QATEEKQRGAEKQSRLLEEKVRAL 1006
Cdd:COG1196 756 LPEPPDLEELERELERLEREIEAL 779
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
688-854 |
2.52e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 2.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 688 ALEREKDDMETKLLHLEDVVRALEKHVDLREN---------------DRLEFHRLSEENTLLKNDLGRVRQELEAAESTH 752
Cdd:COG4913 239 RAHEALEDAREQIELLEPIRELAERYAAARERlaeleylraalrlwfAQRRLELLEAELEELRAELARLEAELERLEARL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 753 DAQRKEIEVLK--------KDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEE 824
Cdd:COG4913 319 DALREELDELEaqirgnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEE 398
|
170 180 190
....*....|....*....|....*....|....
gi 768013530 825 VVRSGQQQ----SDQIQKLRVELECLNQEHQSLQ 854
Cdd:COG4913 399 ELEALEEAlaeaEAALRDLRRELRELEAEIASLE 432
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
601-1003 |
2.52e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 45.28 E-value: 2.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 601 RPAASCRGQAERL--QAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSLPS--HLQLADPQGSwQEQ 676
Cdd:PLN02939 30 RLAVSCRARRRGFssQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSddDHNRASMQRD-EAI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 677 LAAPEEgetkiALEREKDDMETKLLHLEDVVRALekhvdlrendrlefhRLSEENTLLKNDlGRVR--QELEAAESTHDA 754
Cdd:PLN02939 109 AAIDNE-----QQTNSKDGEQLSDFQLEDLVGMI---------------QNAEKNILLLNQ-ARLQalEDLEKILTEKEA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 755 QRKEIEVLKKDKEKACSEM----------EVLNRQNQNYKDQLSQLNVR----VLQLGQEASTHQAQNEEHRVTIQMLTQ 820
Cdd:PLN02939 168 LQGKINILEMRLSETDARIklaaqekihvEILEEQLEKLRNELLIRGATeglcVHSLSKELDVLKEENMLLKDDIQFLKA 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 821 SLEEVVRSGQQqsdqiqklrveLECLNQEHQSLQLPWSELTQTLEESQDQVqgahLRLRQAQAQHLQEvrlvpqdRVAEL 900
Cdd:PLN02939 248 ELIEVAETEER-----------VFKLEKERSLLDASLRELESKFIVAQEDV----SKLSPLQYDCWWE-------KVENL 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 901 HRLL---SLQGEQARRRLDaQREEHEKQLKATEERVEEAEMILKNMEM--LLQEKVDKLKEQFEKNTKSDLLLKELYven 975
Cdd:PLN02939 306 QDLLdraTNQVEKAALVLD-QNQDLRDKVDKLEASLKEANVSKFSSYKveLLQQKLKLLEERLQASDHEIHSYIQLY--- 381
|
410 420
....*....|....*....|....*...
gi 768013530 976 AHLVRALQATEEKQRgAEKQSRLLEEKV 1003
Cdd:PLN02939 382 QESIKEFQDTLSKLK-EESKKRSLEHPA 408
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
743-1017 |
2.75e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.51 E-value: 2.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 743 QELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSL 822
Cdd:COG4372 31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 823 EEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHR 902
Cdd:COG4372 111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLK 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 903 LLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRAL 982
Cdd:COG4372 191 EANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVE 270
|
250 260 270
....*....|....*....|....*....|....*
gi 768013530 983 QATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAA 1017
Cdd:COG4372 271 KDTEEEELEIAALELEALEEAALELKLLALLLNLA 305
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
614-1017 |
3.97e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 44.56 E-value: 3.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 614 QAIQEERARSWSRgtQEQASEQQARAEGALEPGCHKhsvevARRGSLPSHLQLA-DPQGSWQEQLAAPEegetkiALERE 692
Cdd:COG3096 286 RALELRRELFGAR--RQLAEEQYRLVEMARELEELS-----ARESDLEQDYQAAsDHLNLVQTALRQQE------KIERY 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 693 KDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLkkDKEKACSE 772
Cdd:COG3096 353 QEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQAL--EKARALCG 430
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 773 MEVLNRQN-----QNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRS--GQQQSDQIQKLRvELEC 845
Cdd:COG3096 431 LPDLTPENaedylAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSqaWQTARELLRRYR-SQQA 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 846 LNQEHQSLQLPWSELTQTLEESQDQVqgahlRLRQAQAQHLQEVRlvpqDRVAELHRLLSlqgeqarrRLDAQREEHEKQ 925
Cdd:COG3096 510 LAQRLQQLRAQLAELEQRLRQQQNAE-----RLLEEFCQRIGQQL----DAAEELEELLA--------ELEAQLEELEEQ 572
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 926 LKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKEL--YVENAHLV-RALQATEEKQRGAEKQSRLLEEK 1002
Cdd:COG3096 573 AAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSgeALADSQEVtAAMQQLLEREREATVERDELAAR 652
|
410
....*....|....*
gi 768013530 1003 VRALNKLVSRIAPAA 1017
Cdd:COG3096 653 KQALESQIERLSQPG 667
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
688-873 |
4.22e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 4.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 688 ALEREKDDMETKLLHLE-DVVRALEKHVDLR---ENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLK 763
Cdd:TIGR02169 312 EKERELEDAEERLAKLEaEIDKLLAEIEELEreiEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 764 KDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQ-------NEEHRVTIQMLTQSLEEVVRSGQQQSDQI 836
Cdd:TIGR02169 392 EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKineleeeKEDKALEIKKQEWKLEQLAADLSKYEQEL 471
|
170 180 190
....*....|....*....|....*....|....*..
gi 768013530 837 QKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQG 873
Cdd:TIGR02169 472 YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRG 508
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
753-936 |
6.91e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 6.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 753 DAQRKeIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVR--VLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSgq 830
Cdd:COG4913 607 DNRAK-LAALEAELAELEEELAEAEERLEALEAELDALQERreALQRLAEYSWDEIDVASAEREIAELEAELERLDAS-- 683
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 831 qqSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAEL-HRLLSLQGE 909
Cdd:COG4913 684 --SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLeERFAAALGD 761
|
170 180 190
....*....|....*....|....*....|.
gi 768013530 910 ----QARRRLDAQREEHEKQLKATEERVEEA 936
Cdd:COG4913 762 averELRENLEERIDALRARLNRAEEELERA 792
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
727-1013 |
8.24e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 43.36 E-value: 8.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 727 LSEENTLLKNDLgrvRQELEAAESThDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQ-------------LSQLNVR 793
Cdd:PRK11281 54 LEAEDKLVQQDL---EQTLALLDKI-DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDndeetretlstlsLRQLESR 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 794 VLQLGQEASTHQ-------------------AQNE--EHRVTIQMLTQSLEEVVRSGQQQS-DQIQKLRVELECLNQ--E 849
Cdd:PRK11281 130 LAQTLDQLQNAQndlaeynsqlvslqtqperAQAAlyANSQRLQQIRNLLKGGKVGGKALRpSQRVLLQAEQALLNAqnD 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 850 HQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRlvpqdrvaelhrllslqgeqarrrldaqreeHEKQLKAT 929
Cdd:PRK11281 210 LQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAI-------------------------------NSKRLTLS 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 930 EERVEEAEmilkNMEMLLQEKVDKL-KEQFEKNTK-SDLLLK-----------ELYVENAhLVRALQATeekqrgaekqs 996
Cdd:PRK11281 259 EKTVQEAQ----SQDEAARIQANPLvAQELEINLQlSQRLLKateklntltqqNLRVKNW-LDRLTQSE----------- 322
|
330
....*....|....*....
gi 768013530 997 RLLEEKVRALNK--LVSRI 1013
Cdd:PRK11281 323 RNIKEQISVLKGslLLSRI 341
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
684-1007 |
8.70e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.50 E-value: 8.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 684 ETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEentLLKNDLGRVRQELEAAESTHDAQRKEIEVLK 763
Cdd:TIGR00606 688 QTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAP---GRQSIIDLKEKEIPELRNKLQKVNRDIQRLK 764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 764 KDKEKACSEMEVLNRQNQNYKDQLSQLNVrvlqlgqeasthqaqneehrvtIQMLTQSLEEVVRSGQQQSDQIQKLRVEL 843
Cdd:TIGR00606 765 NDIEEQETLLGTIMPEEESAKVCLTDVTI----------------------MERFQMELKDVERKIAQQAAKLQGSDLDR 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 844 EC--LNQEHQSLQLPWSELTQTLEESQDQVQGahlrlRQAQAQHLQEvrlvpqdRVAEL--HRLLSLQGEQARRRLDAQR 919
Cdd:TIGR00606 823 TVqqVNQEKQEKQHELDTVVSKIELNRKLIQD-----QQEQIQHLKS-------KTNELksEKLQIGTNLQRRQQFEEQL 890
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 920 EEHEKQLK----ATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEK-QRGAEK 994
Cdd:TIGR00606 891 VELSTEVQslirEIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKiQDGKDD 970
|
330
....*....|...
gi 768013530 995 QSRLLEEKVRALN 1007
Cdd:TIGR00606 971 YLKQKETELNTVN 983
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
607-962 |
1.07e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.19 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 607 RGQAERLQAIQEERARSWSRGTQEQASEQQARAegalepgchkhsvEVARRGSLPSHlqladpqgswQEQLAAPEEGE-T 685
Cdd:pfam17380 295 KMEQERLRQEKEEKAREVERRRKLEEAEKARQA-------------EMDRQAAIYAE----------QERMAMERERElE 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 686 KIALEREKDDMETklLHLEDVVRALEKhvdLRENDRLEFHRLSeentllKNDlgRVRQELEAAesthdaqrKEIEVLKKD 765
Cdd:pfam17380 352 RIRQEERKRELER--IRQEEIAMEISR---MRELERLQMERQQ------KNE--RVRQELEAA--------RKVKILEEE 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 766 KEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQM-LTQSLEEVVRSGQQQSDQIQKLRVELE 844
Cdd:pfam17380 411 RQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVeRLRQQEEERKRKKLELEKEKRDRKRAE 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 845 CLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRvaelhrllslqgeQARRRLDAQREEHEK 924
Cdd:pfam17380 491 EQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEER-------------RKQQEMEERRRIQEQ 557
|
330 340 350
....*....|....*....|....*....|....*....
gi 768013530 925 QLKATEERvEEAEMILKNMEMLLQ-EKVDKLKEQFEKNT 962
Cdd:pfam17380 558 MRKATEER-SRLEAMEREREMMRQiVESEKARAEYEATT 595
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
715-1014 |
1.11e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.29 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 715 DLRENDRLEFHRLSEEntlLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRV 794
Cdd:pfam12128 586 DLKRIDVPEWAASEEE---LRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEK 662
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 795 ----LQLGQEASTHQAQNEEHRVTIQ-MLTQSLEEVVRSGQQQSDQIQKLRVELeclnqehqslQLPWSELTQTLEESQD 869
Cdd:pfam12128 663 qsekDKKNKALAERKDSANERLNSLEaQLKQLDKKHQAWLEEQKEQKREARTEK----------QAYWQVVEGALDAQLA 732
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 870 QVQGAHLRLRQAQAQHLQEVRlvpqdrvAELHRLLSLQG--EQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLL 947
Cdd:pfam12128 733 LLKAAIAARRSGAKAELKALE-------TWYKRDLASLGvdPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETW 805
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 768013530 948 QEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGA-EKQSRLLEEKVRALNKLVSRIA 1014
Cdd:pfam12128 806 LQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKAsEKQQVRLSENLRGLRCEMSKLA 873
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
743-1014 |
1.19e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.03 E-value: 1.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 743 QELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYK---DQLSQLNVRVLQLGQEasthqaqNEEHRVTIQMLT 819
Cdd:TIGR00618 542 TSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKediPNLQNITVRLQDLTEK-------LSEAEDMLACEQ 614
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 820 QSLEEvvrsgqQQSDQIQKLRVELEcLNQEHQSLQLPWSELTQTLEE-SQDQVQGAHLRLRQAQAQHLQEVRLVPQdrvA 898
Cdd:TIGR00618 615 HALLR------KLQPEQDLQDVRLH-LQQCSQELALKLTALHALQLTlTQERVREHALSIRVLPKELLASRQLALQ---K 684
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 899 ELHRLLSLQG--EQARRRLDAQREEHEKQLKATEERVEEAEMI------LKNMEMLLQEKVDKLKEQFekntksDLLLKE 970
Cdd:TIGR00618 685 MQSEKEQLTYwkEMLAQCQTLLRELETHIEEYDREFNEIENASsslgsdLAAREDALNQSLKELMHQA------RTVLKA 758
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 768013530 971 LyvENAHLVRALQATEEKQRGAEKQ--SRLLEEKVRALNKLVSRIA 1014
Cdd:TIGR00618 759 R--TEAHFNNNEEVTAALQTGAELShlAAEIQFFNRLREEDTHLLK 802
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
12-269 |
1.33e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 1.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 12 QGYRERLSLLRSEVEAERELfWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLsdserlalk 91
Cdd:TIGR02168 701 AELRKELEELEEELEQLRKE-LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL--------- 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 92 lqkdlefvlkDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEglwaRLPKNRHSPSWSPDGRRRQLPGL 171
Cdd:TIGR02168 771 ----------EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT----LLNEEAANLRERLESLERRIAAT 836
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 172 GPAgISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKDMEQArRREVSVLEGQKADLE 251
Cdd:TIGR02168 837 ERR-LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL-SEELRELESKRSELR 914
|
250
....*....|....*...
gi 768013530 252 ELHEKSQEVIWGLQEQLQ 269
Cdd:TIGR02168 915 RELEELREKLAQLELRLE 932
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
744-1009 |
1.33e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 41.82 E-value: 1.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 744 ELEAAESTHDAQRKEIEVLKKDKEKacsemevLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLE 823
Cdd:COG1340 9 SLEELEEKIEELREEIEELKEKRDE-------LNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 824 EVVRSGQQQSDQIQKLRVELECLNQEHQSL--------QLPWSELTQTL---EESQ--DQVQGAHLRLRQAQAQHLQEVR 890
Cdd:COG1340 82 ELNEKLNELREELDELRKELAELNKAGGSIdklrkeieRLEWRQQTEVLspeEEKElvEKIKELEKELEKAKKALEKNEK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 891 LvpQDRVAELhRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEML------LQEKVDKLKEQFEKntks 964
Cdd:COG1340 162 L--KELRAEL-KELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELhkeiveAQEKADELHEEIIE---- 234
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 768013530 965 dllLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKL 1009
Cdd:COG1340 235 ---LQKELRELRKELKKLRKKQRALKREKEKEELEEKAEEIFEKL 276
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
716-949 |
1.49e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 716 LRENDRLEFHRLSEENTLLKNDLGRVRQELEAAEsthdaqrKEIEVLKKDkekacSEMEVLNRQNQNYKDQLSQLNVRVL 795
Cdd:COG3206 162 LEQNLELRREEARKALEFLEEQLPELRKELEEAE-------AALEEFRQK-----NGLVDLSEEAKLLLQQLSELESQLA 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 796 QLGQEASTHQAQNEEHRVTIQMLTQSLEEVvrsgqQQSDQIQKLRVELECLNQEhqslqlpWSELTQTLEESQDQVQGAH 875
Cdd:COG3206 230 EARAELAEAEARLAALRAQLGSGPDALPEL-----LQSPVIQQLRAQLAELEAE-------LAELSARYTPNHPDVIALR 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 876 LRLRQAQAQHLQEVRLVPQDRVAELhRLLSLQGEQARRRLDAQRE------EHEKQLKATEERVEEAEMILKNMEMLLQE 949
Cdd:COG3206 298 AQIAALRAQLQQEAQRILASLEAEL-EALQAREASLQAQLAQLEArlaelpELEAELRRLEREVEVARELYESLLQRLEE 376
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
674-1008 |
1.58e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 42.33 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 674 QEQLAAPEEGETKIA-LEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEfhrLSEENTLLKNDLGRVRQELEAAESTH 752
Cdd:PRK02224 240 DEVLEEHEERREELEtLEAEIEDLRETIAETEREREELAEEVRDLRERLEE---LEEERDDLLAEAGLDDADAEAVEARR 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 753 DAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQ 832
Cdd:PRK02224 317 EELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEEL 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 833 SDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQA-----------QHLQEVRLVP-----QDR 896
Cdd:PRK02224 397 RERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAlleagkcpecgQPVEGSPHVEtieedRER 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 897 VAELHRLLslqgEQARRRLDAQREEHE--KQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKntksdllLKELYVE 974
Cdd:PRK02224 477 VEELEAEL----EDLEEEVEEVEERLEraEDLVEAEDRIERLEERREDLEELIAERRETIEEKRER-------AEELRER 545
|
330 340 350
....*....|....*....|....*....|....
gi 768013530 975 NAHLVRALQATEEKQRGAEKQSRLLEEKVRALNK 1008
Cdd:PRK02224 546 AAELEAEAEEKREAAAEAEEEAEEAREEVAELNS 579
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
681-1008 |
2.64e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.97 E-value: 2.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 681 EEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIE 760
Cdd:PRK03918 197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 761 VLK------KDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQ---NEEHRVTIQMLTQSLEEVVR---- 827
Cdd:PRK03918 277 ELEekvkelKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERikeLEEKEERLEELKKKLKELEKrlee 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 828 ---------SGQQQSDQIQKLRVELECLNQEH------------QSLQLPWSELTQ---TLEESQDQVQGAHLRLRQAQA 883
Cdd:PRK03918 357 leerhelyeEAKAKKEELERLKKRLTGLTPEKlekeleelekakEEIEEEISKITArigELKKEIKELKKAIEELKKAKG 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 884 QHLQEVRLVPQDRVAELHRLLSLQGEQARRRLdAQREEHEKQLKATEERVE----EAEMILKNMEML-----LQEKVDKL 954
Cdd:PRK03918 437 KCPVCGRELTEEHRKELLEEYTAELKRIEKEL-KEIEEKERKLRKELRELEkvlkKESELIKLKELAeqlkeLEEKLKKY 515
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 768013530 955 -KEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNK 1008
Cdd:PRK03918 516 nLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEE 570
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
688-844 |
3.31e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.44 E-value: 3.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 688 ALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTL------LKNDLGRVRQELEAAESTHD-------- 753
Cdd:COG4913 614 ALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDeidvasAEREIAELEAELERLDASSDdlaaleeq 693
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 754 --AQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQ 831
Cdd:COG4913 694 leELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEE 773
|
170
....*....|...
gi 768013530 832 QSDQIQKLRVELE 844
Cdd:COG4913 774 RIDALRARLNRAE 786
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
691-1006 |
3.33e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 41.70 E-value: 3.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 691 REKDDMETKLLHLEDVV-RALEKHVDLRENDRlEFHRLSEENTLLKNDLgRVRQELEA-AESTH---DAQRKEIEVLKKD 765
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKeRQQKAESELKELEK-KHQQLCEEKNALQEQL-QAETELCAeAEEMRarlAARKQELEEILHE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 766 KEKACSEMEVLNRQNQNYKDQLSQlNVRVL--QLGQEASTHQAQNEEhRVTIQMLTQSLEEVVRSGQQQSDQIQKlrvel 843
Cdd:pfam01576 80 LESRLEEEEERSQQLQNEKKKMQQ-HIQDLeeQLDEEEAARQKLQLE-KVTTEAKIKKLEEDILLLEDQNSKLSK----- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 844 eclnqEHQSLQLPWSELTQTLEESQDQVQG-AHLRLRQAQAQHLQEVRLVPQDRvaelhrlLSLQGEQARRRLDAQREEH 922
Cdd:pfam01576 153 -----ERKLLEERISEFTSNLAEEEEKAKSlSKLKNKHEAMISDLEERLKKEEK-------GRQELEKAKRKLEGESTDL 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 923 EKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEK 1002
Cdd:pfam01576 221 QEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEE 300
|
....
gi 768013530 1003 VRAL 1006
Cdd:pfam01576 301 LEAL 304
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
680-785 |
4.75e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.00 E-value: 4.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 680 PEEGETKIALEREKDDMETKLLHLEDVVRALEKHV-DLREndrlEFHRLSEENTLLKNDLGRVRQELEA-AESTHDAQR- 756
Cdd:COG2433 395 PEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVeELEA----ELEEKDERIERLERELSEARSEERReIRKDREISRl 470
|
90 100 110
....*....|....*....|....*....|
gi 768013530 757 -KEIEVLKKDKEKACSEMEVLNRQNQNYKD 785
Cdd:COG2433 471 dREIERLERELEEERERIEELKRKLERLKE 500
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
578-1003 |
5.48e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 40.87 E-value: 5.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 578 ELPLLGTERDA-SQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEgalepgCHKHSVEVAR 656
Cdd:pfam15921 357 ELTEARTERDQfSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE------LDDRNMEVQR 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 657 RGSLPSHLQlADPQGSWQEQLAA---------------PEEGETKIALEREKDDMETKLLHLEDVVRALEK-HVDLREND 720
Cdd:pfam15921 431 LEALLKAMK-SECQGQMERQMAAiqgkneslekvssltAQLESTKEMLRKVVEELTAKKMTLESSERTVSDlTASLQEKE 509
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 721 RlEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRK---EIEVLKKDKEKACSEMEVLNRQNQNykdqLSQLnvrVLQL 797
Cdd:pfam15921 510 R-AIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNvqtECEALKLQMAEKDKVIEILRQQIEN----MTQL---VGQH 581
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 798 GQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEEsqdqvqgahlr 877
Cdd:pfam15921 582 GRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKD----------- 650
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 878 LRQAQAQHLQEVRLVPQD--RVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEM---------- 945
Cdd:pfam15921 651 IKQERDQLLNEVKTSRNElnSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGsdghamkvam 730
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768013530 946 --------------LLQEKVDKLKEQFEKNTKSDLLLKElyvENAHLVRALQ--ATEEKQRGAE-----KQSRLLEEKV 1003
Cdd:pfam15921 731 gmqkqitakrgqidALQSKIQFLEEAMTNANKEKHFLKE---EKNKLSQELStvATEKNKMAGElevlrSQERRLKEKV 806
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
50-149 |
6.51e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 39.12 E-value: 6.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 50 LQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDK--LEPQSAELLAQEERFAAVLKEYEL 127
Cdd:pfam13851 31 LKEEIAELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRKQLENYEKDKqsLKNLKARLKVLEKELKDLKWEHEV 110
|
90 100
....*....|....*....|..
gi 768013530 128 kcrdLQDRNDELQAELEGLWAR 149
Cdd:pfam13851 111 ----LEQRFEKVERERDELYDK 128
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
609-1009 |
6.96e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 40.51 E-value: 6.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 609 QAERLQAIQEERARSWSRGTQE--QASEQQARAEGALEPGCHKHSVEVARRGSlpSHLQLADPQGSWQEQLAAPEEGETK 686
Cdd:PTZ00121 1279 KADELKKAEEKKKADEAKKAEEkkKADEAKKKAEEAKKADEAKKKAEEAKKKA--DAAKKKAEEAKKAAEAAKAEAEAAA 1356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 687 IALEREKDDMETKLLHLEDVVRALEKHVDLRENDRL--EFHRLSEENtllKNDLGRVRQELEAAESTHDAQRKEIEVLKK 764
Cdd:PTZ00121 1357 DEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKadEAKKKAEED---KKKADELKKAAAAKKKADEAKKKAEEKKKA 1433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 765 D--KEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRvTIQMLTQSLEEVVRSGQQ--QSDQIQKLR 840
Cdd:PTZ00121 1434 DeaKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK-KADEAKKKAEEAKKKADEakKAAEAKKKA 1512
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 841 VELECLNQEHQSLQLPWSELTQTLEESQ--DQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSL-------QGEQA 911
Cdd:PTZ00121 1513 DEAKKAEEAKKADEAKKAEEAKKADEAKkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALrkaeeakKAEEA 1592
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 912 RRRLDAQREEHEKQLKATEERVEEAEMIlKNMEMLLQEKVDKLKEQFEKNT-----KSDLLLKElyvENAHLVRA----- 981
Cdd:PTZ00121 1593 RIEEVMKLYEEEKKMKAEEAKKAEEAKI-KAEELKKAEEEKKKVEQLKKKEaeekkKAEELKKA---EEENKIKAaeeak 1668
|
410 420 430
....*....|....*....|....*....|....*....
gi 768013530 982 -----------LQATEEKQRGAEKQSRLLEEKVRALNKL 1009
Cdd:PTZ00121 1669 kaeedkkkaeeAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
923-1008 |
7.20e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 40.20 E-value: 7.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 923 EKQLKATEERVEEAEMILKNMEML---LQEKVDKLKEQFEKnTKSDL------LLKELYVENAHLVRALQATEEKQRGAE 993
Cdd:PRK00409 526 EELERELEQKAEEAEALLKEAEKLkeeLEEKKEKLQEEEDK-LLEEAekeaqqAIKEAKKEADEIIKELRQLQKGGYASV 604
|
90
....*....|....*
gi 768013530 994 KqSRLLEEKVRALNK 1008
Cdd:PRK00409 605 K-AHELIEARKRLNK 618
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
829-1008 |
7.23e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.28 E-value: 7.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 829 GQQQSDQIQKLRVELECLNQEHQSLQlpwsELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVP-QDRVAELHRLLS-- 905
Cdd:COG4913 605 GFDNRAKLAALEAELAELEEELAEAE----ERLEALEAELDALQERREALQRLAEYSWDEIDVASaEREIAELEAELErl 680
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 906 LQGEQARRRLDAQREEHEKQLKATEERVEEaemilknmemlLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQAT 985
Cdd:COG4913 681 DASSDDLAALEEQLEELEAELEELEEELDE-----------LKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749
|
170 180
....*....|....*....|....
gi 768013530 986 E-EKQRGAEKQSRLLEEKVRALNK 1008
Cdd:COG4913 750 LlEERFAAALGDAVERELRENLEE 773
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
672-944 |
8.46e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 39.94 E-value: 8.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 672 SWQEQLAAPEEGETKIALEREKDDMETKLLH-LEDVVRALEKhvdlrendRLEFHRLSEENTLLKNDLGRVRQELEAAES 750
Cdd:COG5185 313 SLEEQLAAAEAEQELEESKRETETGIQNLTAeIEQGQESLTE--------NLEAIKEEIENIVGEVELSKSSEELDSFKD 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 751 THDAQRKEIEVLKKDKEKacsemevlnrQNQNYKDQLSQlnvrvlqlgqEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQ 830
Cdd:COG5185 385 TIESTKESLDEIPQNQRG----------YAQEILATLED----------TLKAADRQIEELQRQIEQATSSNEEVSKLLN 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 831 QQSDQIQKLRVELEclNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQ 910
Cdd:COG5185 445 ELISELNKVMREAD--EESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQV 522
|
250 260 270
....*....|....*....|....*....|....
gi 768013530 911 ARRRLDAQREEHEKQLKATEERVEEAEMILKNME 944
Cdd:COG5185 523 AESLKDFMRARGYAHILALENLIPASELIQASNA 556
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
670-1012 |
8.92e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 40.03 E-value: 8.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 670 QGSWQEQLAAPEEGETKIALEREK--DDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEEntllknDLGRVRQELEA 747
Cdd:TIGR00606 232 QLESSREIVKSYENELDPLKNRLKeiEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEK------VFQGTDEQLND 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 748 AESTHDAQRKEIEVLKKDKEKacsEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLE---- 823
Cdd:TIGR00606 306 LYHNHQRTVREKERELVDCQR---ELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLEldgf 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 824 --------------EVVRSGQQ-------------------QSDQIQKLRVELECLNQ----EHQSLQLPWSELTQTLEE 866
Cdd:TIGR00606 383 ergpfserqiknfhTLVIERQEdeaktaaqlcadlqskerlKQEQADEIRDEKKGLGRtielKKEILEKKQEELKFVIKE 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768013530 867 SQDQVQGAH--LRLRQAQAQHLQEVRLVPQDRVAE--LHRLLSLQGEQAR--RRLDAQREEHEKQLKATEERveeaemil 940
Cdd:TIGR00606 463 LQQLEGSSDriLELDQELRKAERELSKAEKNSLTEtlKKEVKSLQNEKADldRKLRKLDQEMEQLNHHTTTR-------- 534
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768013530 941 KNMEMLLQEKVDKLKEQFEKNTK-SDLLLKEL-YVENAhlvRALQATEEKQRGAEKQSRlleEKVRALNKLVSR 1012
Cdd:TIGR00606 535 TQMEMLTKDKMDKDEQIRKIKSRhSDELTSLLgYFPNK---KQLEDWLHSKSKEINQTR---DRLAKLNKELAS 602
|
|
| |
