|
Name |
Accession |
Description |
Interval |
E-value |
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
6-566 |
1.47e-133 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 398.28 E-value: 1.47e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 6 QALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDA----SEVAVE 81
Cdd:pfam00939 1 LTLWWKLLALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLakalSWALSG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 82 YLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPapLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHS 161
Cdd:pfam00939 81 FSSTTTWLVFGAFFISAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 162 SqassnveegsNNPTFELQEPSpqkevtkldngqalpvtsassegrahlsqkhlHLTQCMSLCVCYSASIGGIATLTGTA 241
Cdd:pfam00939 159 A----------FGSDPEKGSER--------------------------------RIGAYLMWTVYQSTSITSAMFLTAMA 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 242 PNLVLQGQINSlfpQNGNVVNFASWFSFAFPTMVILLLLAWLWLQILFLGFNFRKNfgigekmqeqqqAAYCVIQTEHRL 321
Cdd:pfam00939 197 PNLLLLGLMNS---ILGVTITWASWFLAAIPPGVILLLLAPLLLYVLYPPEIKSVP------------DAKAIAKTELKE 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 322 LGPMTFAEKAISILFVILVLLWFTRepgfflgwgnlafpnakGESMVSDGTVAIFIGIIMFIipskfpgltqdpvenpgk 401
Cdd:pfam00939 262 LGPMTFREKALLGLFVLLLLLWIFG-----------------GSLNIDATTVAIIGLALMLL------------------ 306
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 402 lkapLGLLDWK-TVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQS--VPAPAIAIILSLLVATFTECTSNV 478
Cdd:pfam00939 307 ----LRILDWKdIVKNKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSLSgfSPAMAFIIILSLFYLSHYLFASAT 382
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 479 ATTTIFLPILASMAQAICLHP-LYVMLPCTLATSLA-FMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAI 556
Cdd:pfam00939 383 AHTAAMLPIFAAVAQAIPGAPpLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLG 462
|
570
....*....|
gi 767996411 557 NSWGIPLFSL 566
Cdd:pfam00939 463 NWWWKPLGSL 472
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
39-560 |
5.48e-92 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 287.94 E-value: 5.48e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 39 AYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVG 118
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 119 VRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQassnveegsnnptfelqepspqkevtkldngqalp 198
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISP----------------------------------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 199 vtsassegrahlsqkhlhltQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQNGNvvnFASWFSFAFPTMVIll 278
Cdd:cd01115 126 --------------------SRLLMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQGFS---FFEFTPIGLPLLII-- 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 279 llawlwlqilflgfnfrknfgigekmqeqqqaaycviqtehrllgpmtfaekaisilfVILVLLWFTREPGFFLGWGNLA 358
Cdd:cd01115 181 ----------------------------------------------------------GLLYLWFIFRLAVLIITIVLLA 202
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 359 FPNA-KGESMVSDGTVAIFIGIIMFiipskfpgltqdpvenpgklkaplGLLDWKTVNQKMPWNIVLLLGGGYALAKGSE 437
Cdd:cd01115 203 ALAAiTGLLPVSVAIAIGAIVLVFG------------------------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALE 258
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 438 RSGLSEWLGNKLTP-LQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPLYVMLPCTLATSLAFML 516
Cdd:cd01115 259 SSGAAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFML 338
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 767996411 517 PVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSWG 560
Cdd:cd01115 339 PVGTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLIW 382
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
91-559 |
5.14e-75 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 243.52 E-value: 5.14e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 91 FGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSsqassnvEE 170
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGS-------EK 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 171 GSNNPTFelqepspqkevtkldngqalpvtsassegrahlsqkhlhltqcMSLCVCYSASIGGIATLTGTAPNLVLQGQI 250
Cdd:COG0471 74 RSKFGSA-------------------------------------------LLLPIAFAASIGGMGTLIGTPPNLIAAGLL 110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 251 NSLFPQNgnvVNFASWFSFAFPTMVILLLLAWLwlqilFLGFNFRKNFGIGEKMQEqqqaaycVIQTEHRLLGPMTFAEK 330
Cdd:COG0471 111 EEATGIP---ISFFEWMLVGLPVALVGLLLLWL-----VLYRLLPPEIKEVPGSKE-------VIREELAELGPLSRREK 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 331 AISILFVILVLLWFTrepGFFLGwgnlafpnakgesmVSDGTVAIFIGIIMFIipskfpgltqdpvenpgklkapLGLLD 410
Cdd:COG0471 176 IALAIFALTVLLWIT---GSLHG--------------IPIAVVALLGAVLLLL----------------------TGVLT 216
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 411 WKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTP-LQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILA 489
Cdd:COG0471 217 WKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLPlLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAI 296
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 490 SMAQAICLHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSW 559
Cdd:COG0471 297 SLAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
33-559 |
9.73e-48 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 172.91 E-value: 9.73e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 33 SKEAYCAYAI-ILMALFWCTEALPLAVTALFP-LILFPMMGIVDASEV--AVEYLKDSNL-LFFGGLLVAIAVEHWNLHK 107
Cdd:TIGR00785 7 NSGAWLLLAIfVAAIVGWILEPLPLPVTALLAiPIIAVLLGVLSAFKFknALSGFADPTIwLFFGAFILATALVKTGLGK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 108 RIALRVLLIVGVRPAPL-ILGFMLVTAFLSMWISNTA-TSAMMVPIAHAVLDQLHSSqassnveegsnnptfelqepspq 185
Cdd:TIGR00785 87 RIAYKLVGKMGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLLPLLGSK----------------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 186 kevtkldngqalPVTSASSEGRAhlsqkhlhltqcMSLCVCYSASIGGIATLTGTAPNLVLQGQinsLFPQNGNVVNFAS 265
Cdd:TIGR00785 144 ------------PEKSPRKIGKY------------LMLGIAYSASIGSSGFLTGSAPNALAAGI---LSKILGIQISWGD 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 266 WFSFAFPTMVILLLLAWLWLQILFLGfnfrknfgigEKMQEQQQAAycVIQTEHRLLGPMTFAEKAISILFVILVLLWFT 345
Cdd:TIGR00785 197 WFLAGLPLGIILLLLVPLLLYVLFPP----------ELKLKDEVDL--WAKEELEEMGPMSFREKALLGIFLLALLLWIF 264
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 346 repGFFLGwgnlafpnakgesmVSDGTVAIFIGIIMFIipskfpgltqdpvenpgklkapLGLLDWKTVNQ-KMPWNIVL 424
Cdd:TIGR00785 265 ---GGSLG--------------INASVVALLAVVLMLF----------------------LGIVTWKDIQKnKVAWNTLI 305
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 425 LLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATF--TECTSNVATTTIFLPILASMAQAICLHPLYV 502
Cdd:TIGR00785 306 LFGGLIGLAGGLKKSGFIKWFSEKLVGILDGLSPTIAVLVLVVLFYIilYFFASNTAHTAALVPIFFSVASAQGIPLELL 385
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 767996411 503 MLPCTLATSLA-FMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSW 559
Cdd:TIGR00785 386 ALALALSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVGTLW 443
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
6-566 |
1.47e-133 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 398.28 E-value: 1.47e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 6 QALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDA----SEVAVE 81
Cdd:pfam00939 1 LTLWWKLLALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLakalSWALSG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 82 YLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPapLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHS 161
Cdd:pfam00939 81 FSSTTTWLVFGAFFISAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 162 SqassnveegsNNPTFELQEPSpqkevtkldngqalpvtsassegrahlsqkhlHLTQCMSLCVCYSASIGGIATLTGTA 241
Cdd:pfam00939 159 A----------FGSDPEKGSER--------------------------------RIGAYLMWTVYQSTSITSAMFLTAMA 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 242 PNLVLQGQINSlfpQNGNVVNFASWFSFAFPTMVILLLLAWLWLQILFLGFNFRKNfgigekmqeqqqAAYCVIQTEHRL 321
Cdd:pfam00939 197 PNLLLLGLMNS---ILGVTITWASWFLAAIPPGVILLLLAPLLLYVLYPPEIKSVP------------DAKAIAKTELKE 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 322 LGPMTFAEKAISILFVILVLLWFTRepgfflgwgnlafpnakGESMVSDGTVAIFIGIIMFIipskfpgltqdpvenpgk 401
Cdd:pfam00939 262 LGPMTFREKALLGLFVLLLLLWIFG-----------------GSLNIDATTVAIIGLALMLL------------------ 306
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 402 lkapLGLLDWK-TVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQS--VPAPAIAIILSLLVATFTECTSNV 478
Cdd:pfam00939 307 ----LRILDWKdIVKNKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSLSgfSPAMAFIIILSLFYLSHYLFASAT 382
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 479 ATTTIFLPILASMAQAICLHP-LYVMLPCTLATSLA-FMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAI 556
Cdd:pfam00939 383 AHTAAMLPIFAAVAQAIPGAPpLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLG 462
|
570
....*....|
gi 767996411 557 NSWGIPLFSL 566
Cdd:pfam00939 463 NWWWKPLGSL 472
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
39-560 |
5.48e-92 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 287.94 E-value: 5.48e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 39 AYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVG 118
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 119 VRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQassnveegsnnptfelqepspqkevtkldngqalp 198
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISP----------------------------------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 199 vtsassegrahlsqkhlhltQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQNGNvvnFASWFSFAFPTMVIll 278
Cdd:cd01115 126 --------------------SRLLMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQGFS---FFEFTPIGLPLLII-- 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 279 llawlwlqilflgfnfrknfgigekmqeqqqaaycviqtehrllgpmtfaekaisilfVILVLLWFTREPGFFLGWGNLA 358
Cdd:cd01115 181 ----------------------------------------------------------GLLYLWFIFRLAVLIITIVLLA 202
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 359 FPNA-KGESMVSDGTVAIFIGIIMFiipskfpgltqdpvenpgklkaplGLLDWKTVNQKMPWNIVLLLGGGYALAKGSE 437
Cdd:cd01115 203 ALAAiTGLLPVSVAIAIGAIVLVFG------------------------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALE 258
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 438 RSGLSEWLGNKLTP-LQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPLYVMLPCTLATSLAFML 516
Cdd:cd01115 259 SSGAAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFML 338
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 767996411 517 PVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSWG 560
Cdd:cd01115 339 PVGTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLIW 382
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
91-559 |
5.14e-75 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 243.52 E-value: 5.14e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 91 FGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSsqassnvEE 170
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGS-------EK 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 171 GSNNPTFelqepspqkevtkldngqalpvtsassegrahlsqkhlhltqcMSLCVCYSASIGGIATLTGTAPNLVLQGQI 250
Cdd:COG0471 74 RSKFGSA-------------------------------------------LLLPIAFAASIGGMGTLIGTPPNLIAAGLL 110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 251 NSLFPQNgnvVNFASWFSFAFPTMVILLLLAWLwlqilFLGFNFRKNFGIGEKMQEqqqaaycVIQTEHRLLGPMTFAEK 330
Cdd:COG0471 111 EEATGIP---ISFFEWMLVGLPVALVGLLLLWL-----VLYRLLPPEIKEVPGSKE-------VIREELAELGPLSRREK 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 331 AISILFVILVLLWFTrepGFFLGwgnlafpnakgesmVSDGTVAIFIGIIMFIipskfpgltqdpvenpgklkapLGLLD 410
Cdd:COG0471 176 IALAIFALTVLLWIT---GSLHG--------------IPIAVVALLGAVLLLL----------------------TGVLT 216
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 411 WKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTP-LQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILA 489
Cdd:COG0471 217 WKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLPlLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAI 296
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 490 SMAQAICLHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSW 559
Cdd:COG0471 297 SLAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
33-559 |
9.73e-48 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 172.91 E-value: 9.73e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 33 SKEAYCAYAI-ILMALFWCTEALPLAVTALFP-LILFPMMGIVDASEV--AVEYLKDSNL-LFFGGLLVAIAVEHWNLHK 107
Cdd:TIGR00785 7 NSGAWLLLAIfVAAIVGWILEPLPLPVTALLAiPIIAVLLGVLSAFKFknALSGFADPTIwLFFGAFILATALVKTGLGK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 108 RIALRVLLIVGVRPAPL-ILGFMLVTAFLSMWISNTA-TSAMMVPIAHAVLDQLHSSqassnveegsnnptfelqepspq 185
Cdd:TIGR00785 87 RIAYKLVGKMGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLLPLLGSK----------------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 186 kevtkldngqalPVTSASSEGRAhlsqkhlhltqcMSLCVCYSASIGGIATLTGTAPNLVLQGQinsLFPQNGNVVNFAS 265
Cdd:TIGR00785 144 ------------PEKSPRKIGKY------------LMLGIAYSASIGSSGFLTGSAPNALAAGI---LSKILGIQISWGD 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 266 WFSFAFPTMVILLLLAWLWLQILFLGfnfrknfgigEKMQEQQQAAycVIQTEHRLLGPMTFAEKAISILFVILVLLWFT 345
Cdd:TIGR00785 197 WFLAGLPLGIILLLLVPLLLYVLFPP----------ELKLKDEVDL--WAKEELEEMGPMSFREKALLGIFLLALLLWIF 264
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 346 repGFFLGwgnlafpnakgesmVSDGTVAIFIGIIMFIipskfpgltqdpvenpgklkapLGLLDWKTVNQ-KMPWNIVL 424
Cdd:TIGR00785 265 ---GGSLG--------------INASVVALLAVVLMLF----------------------LGIVTWKDIQKnKVAWNTLI 305
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 425 LLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATF--TECTSNVATTTIFLPILASMAQAICLHPLYV 502
Cdd:TIGR00785 306 LFGGLIGLAGGLKKSGFIKWFSEKLVGILDGLSPTIAVLVLVVLFYIilYFFASNTAHTAALVPIFFSVASAQGIPLELL 385
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 767996411 503 MLPCTLATSLA-FMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSW 559
Cdd:TIGR00785 386 ALALALSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVGTLW 443
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
46-556 |
3.26e-42 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 156.64 E-value: 3.26e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 46 ALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIvGVRPAPLI 125
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARA-SKGSRRLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 126 LGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQassnveegsnnptfelqepspqkevtkldngqalpvtsasse 205
Cdd:cd00625 80 LLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSP------------------------------------------ 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 206 grahlsqkhlhlTQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINslfpqngnvVNFASWFSFAFPTMVILLLLAWLWL 285
Cdd:cd00625 118 ------------PVPLLLALAFAANIGGAATPIGNPPNLIIASLSG---------LGFLDFLAFMAPPALGLLLLLLGLL 176
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 286 QILFLGFNFRKNFGIGEKMQEQQQAAYcviqtehrllgpmTFAEKAISILFVILVLLWFtrepGFFLGWGNLafpnakge 365
Cdd:cd00625 177 YLLFRKKLLLPDEDKLTVLAEPLPARP-------------LLKKFLLLALLLLLLFVLL----FFFLIPLGL-------- 231
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 366 sMVSDGTVAIFIGIIMFiipskfpgltqdpvenpgklkaplglLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWL 445
Cdd:cd00625 232 -IALLGALLLLLLLVRG--------------------------LDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWL 284
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 446 GNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASM-----AQAICLHPLYVMLPCTLATSLAFMLPVAT 520
Cdd:cd00625 285 AELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLappepAWLALALGSTLGGNLTLIGSLANLIPLGA 364
|
490 500 510
....*....|....*....|....*....|....*.
gi 767996411 521 PPNAIVfsfgDLKVLDMARAGFLLNIIGVLIIALAI 556
Cdd:cd00625 365 AENAGV----GISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
46-504 |
1.06e-25 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 108.55 E-value: 1.06e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 46 ALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLI 125
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 126 LGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSqassnveegsnnptfelqePSPqkevtkldngqalpvtsasse 205
Cdd:pfam03600 81 VALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLP-------------------PSP--------------------- 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 206 grahlsqkhlhltqcMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQNGNVVNFASWFSFAFPTMVillllawlwl 285
Cdd:pfam03600 121 ---------------LLIALAFAANIGGTATPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGLL---------- 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 286 qilFLGFNFRKNFGIGEKMQEQQQAAYCVIQTEHRLLGpmtfaekaisILFVILVLLWFTREPGFFLGWGNLAfpnakge 365
Cdd:pfam03600 176 ---PLLLIFRKLLPVRKEEEAELEELRKRAIKDKLLLA----------ISALVLALVILGFLLLSVLALAGAL------- 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 366 smvsdgtvaifigiimfiipskfpgltqdpvenpgkLKAPLGLLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWL 445
Cdd:pfam03600 236 ------------------------------------LLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADAL 279
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 767996411 446 GNKLTPLqsVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPLYVML 504
Cdd:pfam03600 280 ADALGGL--SGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGDPDPLA 336
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
405-556 |
3.89e-10 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 61.56 E-value: 3.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 405 PLGLLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIF 484
Cdd:pfam03600 24 LLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLLVALMLATALLSAFLSNDGTVLIM 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767996411 485 LPILASMAQAICLHPLYVMLPCTLATSLAFML-PVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAI 556
Cdd:pfam03600 104 IPIVLALARRLGLPPSPLLIALAFAANIGGTAtPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGLLP 176
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
42-160 |
1.82e-08 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 56.70 E-value: 1.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 42 IILMALFWCTEA---LPLAVTALFPLILFPMMGIVDASEvAVEYLKDSNLLFFGGLL-VAIAVEHWNLHKRIALRVL-LI 116
Cdd:COG0471 181 FALTVLLWITGSlhgIPIAVVALLGAVLLLLTGVLTWKD-AYKSIPWGVLLLFGGGLaLGAALEKTGLAAWLADALLpLL 259
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 767996411 117 VGVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLH 160
Cdd:COG0471 260 GGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQALG 303
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
406-556 |
1.47e-07 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 53.98 E-value: 1.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 406 LGLLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFL 485
Cdd:COG1055 39 LGVVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLT 118
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767996411 486 PILASMAQAICLHPLYVMLPCTLATSLA-FMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAI 556
Cdd:COG1055 119 PVVLAIARRLGLNPVPFLIAIVFAANIGgAATPIGNPTNIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVL 190
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
421-563 |
2.28e-07 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 53.36 E-value: 2.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 421 NIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPL 500
Cdd:cd01115 47 PAVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPS 126
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 501 YVMLPCTLATSLAFML-PVATPPNAIV------FSFGDLKVLDMARAGFLLNIIGVLIIALAINSWGIPL 563
Cdd:cd01115 127 RLLMPLAFAASIGGMLtLIGTPPNLVAsgylesLGGQGFSFFEFTPIGLPLLIIGLLYLWFIFRLAVLII 196
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
8-165 |
3.72e-07 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 52.31 E-value: 3.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 8 LWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSN 87
Cdd:pfam03600 178 LLIFRKLLPVRKEEEAELEELRKRAIKDKLLLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTL 257
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767996411 88 LLFFGGLLVAIAVEHWNLHKRIAlrVLLIVGVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQAS 165
Cdd:pfam03600 258 LFFAGLFILVGALEKTGLADALA--DALGGLSGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGDPD 333
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
41-159 |
4.67e-05 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 45.89 E-value: 4.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 41 AIILMALFWctEALPLAVTALFPLILFPMMGIVDASEvAVEYLkDSNLLFF--GGLLVAIAVEHWNLHKRIALRVLLIVG 118
Cdd:COG1055 12 TYLLIILEP--RGLNRAVAALLGAALLLLLGVVSLED-ALEAI-DWNTILFllGMMIIVAILDESGFFEWLAIKLARRAK 87
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 767996411 119 VRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQL 159
Cdd:COG1055 88 GSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRL 128
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
41-154 |
4.80e-05 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 46.09 E-value: 4.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767996411 41 AIILMALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLV-AIAVEHWNLHKRIALRVLLIVGV 119
Cdd:cd00625 215 LLLLFVLLFFFLIPLGLIALLGALLLLLLLVRGLDPEEVLKSVDWGTLLFFAGLFVlVGALESTGLLEWLAELLVALVGL 294
|
90 100 110
....*....|....*....|....*....|....*
gi 767996411 120 RPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHA 154
Cdd:cd00625 295 PPLAALLLIGLLSALLSNFISNVPTVALLLPIAAS 329
|
|
| |
