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Conserved domains on  [gi|767995774|ref|XP_011523490|]
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homologous recombination OB-fold protein isoform X2 [Homo sapiens]

Protein Classification

DUF4539 domain-containing protein( domain architecture ID 10633392)

DUF4539 domain-containing protein may belong to the OB (oligonucleotide/oligosaccharide binding) fold superfamily

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HROB pfam15072
Homologous recombination OB-fold protein; This family represents Homologous recombination ...
 465-548 1.24e-39

Homologous recombination OB-fold protein; This family represents Homologous recombination OB-fold protein (HROB). During homologous recombination, HROB acts by recruiting the MCM8-MCM9 helicase complex to sites of DNA damage to promote DNA repair synthesis.


:

Pssm-ID: 464486  Cd Length: 85  Bit Score: 139.59  E-value: 1.24e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767995774  465 NKVPNMAVMIKSLTRSTM-DASVVFKDPTGEMQGTVHRLLLETCQNELKPGSVLLLKQIGVFSPSLRNHYLNVTPNNLVH 543
Cdd:pfam15072   1 YKVPQLVVIIKSITPSSNgDATVVLKDPTGEIRGTIHRKVLEEYPDELVVGAVLLLKDVSVFSPSPRSHYLNITLNNLVA 80


                  ....*
gi 767995774  544 IYSPD 548
Cdd:pfam15072  81 VFSPE 85
 
Name Accession Description Interval E-value
HROB pfam15072
Homologous recombination OB-fold protein; This family represents Homologous recombination ...
 465-548 1.24e-39

Homologous recombination OB-fold protein; This family represents Homologous recombination OB-fold protein (HROB). During homologous recombination, HROB acts by recruiting the MCM8-MCM9 helicase complex to sites of DNA damage to promote DNA repair synthesis.


Pssm-ID: 464486  Cd Length: 85  Bit Score: 139.59  E-value: 1.24e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767995774  465 NKVPNMAVMIKSLTRSTM-DASVVFKDPTGEMQGTVHRLLLETCQNELKPGSVLLLKQIGVFSPSLRNHYLNVTPNNLVH 543
Cdd:pfam15072   1 YKVPQLVVIIKSITPSSNgDATVVLKDPTGEIRGTIHRKVLEEYPDELVVGAVLLLKDVSVFSPSPRSHYLNITLNNLVA 80


                  ....*
gi 767995774  544 IYSPD 548
Cdd:pfam15072  81 VFSPE 85
 
Name Accession Description Interval E-value
HROB pfam15072
Homologous recombination OB-fold protein; This family represents Homologous recombination ...
 465-548 1.24e-39

Homologous recombination OB-fold protein; This family represents Homologous recombination OB-fold protein (HROB). During homologous recombination, HROB acts by recruiting the MCM8-MCM9 helicase complex to sites of DNA damage to promote DNA repair synthesis.


Pssm-ID: 464486  Cd Length: 85  Bit Score: 139.59  E-value: 1.24e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767995774  465 NKVPNMAVMIKSLTRSTM-DASVVFKDPTGEMQGTVHRLLLETCQNELKPGSVLLLKQIGVFSPSLRNHYLNVTPNNLVH 543
Cdd:pfam15072   1 YKVPQLVVIIKSITPSSNgDATVVLKDPTGEIRGTIHRKVLEEYPDELVVGAVLLLKDVSVFSPSPRSHYLNITLNNLVA 80


                  ....*
gi 767995774  544 IYSPD 548
Cdd:pfam15072  81 VFSPE 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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