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Conserved domains on  [gi|767966108|ref|XP_011518497|]
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palmitoyltransferase ZDHHC13 isoform X6 [Homo sapiens]

Protein Classification

ankyrin repeat domain-containing DHHC palmitoyltransferase family protein( domain architecture ID 12790884)

DHHC family palmitoyltransferase may catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes; contains N-terminal ankyrin repeats;

EC:  2.3.1.-
Gene Ontology:  GO:0043543|GO:0016747
PubMed:  21388813

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DHHC pfam01529
DHHC palmitoyltransferase; This entry refers to the DHHC domain, found in DHHC proteins which ...
 293-429 1.95e-32

DHHC palmitoyltransferase; This entry refers to the DHHC domain, found in DHHC proteins which are palmitoyltransferases. Palmitoylation or, more specifically S-acylation, plays important roles in the regulation of protein localization, stability, and activity. It is a post-translational protein modification that involves the attachment of palmitic acid to Cys residues through a thioester linkage. Protein acyltransferases (PATs), also known as palmitoyltransferases, catalyze this reaction by transferring the palmitoyl group from palmitoyl-CoA to the thiol group of Cys residues. They are characterized by the presence of a 50-residue-long domain called the DHHC domain, which in most but not all cases is also cysteine-rich and gets its name from a highly conserved DHHC signature tetrapeptide (Asp-His-His-Cys). The Cys residue within the DHHC domain forms a stable acyl intermediate and transfers the acyl chain to the Cys residues of a target protein. Some proteins containing a DHHC domain include Drosophila DNZ1 protein, Mouse Abl-philin 2 (Aph2) protein, Mammalian ZDHHC9, Yeast ankyrin repeat-containing protein AKR1, Yeast Erf2 protein, and Arabidopsis thaliana tip growth defective 1.


:

Pssm-ID: 396215  Cd Length: 132  Bit Score: 120.16  E-value: 1.95e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108  293 DFRTFCTSCLIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFK 372
Cdd:pfam01529   3 DELKYCSTCNIYKPPRSKHCRVCNRCVLRFDHHCPWLNNCIGKRNHKYFILFLLYLTLYLILYLVLSLYYLVKLIESSTL 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767966108  373 EDGLWTYLNQivacspWVLYILMLATFHFSWSTFLLLNQLFQIaFLGLTSHERISLQ 429
Cdd:pfam01529  83 FFFLILFLFS------ISIILLILSLFFLLFLGILLFFHLYLI-SRNLTTYEFMKKK 132
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
1-140 1.23e-29

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 117.75  E-value: 1.23e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKviG-PEPTGFLLKFNPSL 79
Cdd:COG0666  102 IVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAAN--GnLEIVKLLLEAGADV 179

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767966108  80 NVVDKiHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHMLK 140
Cdd:COG0666  180 NARDN-DGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLL 239
 
Name Accession Description Interval E-value
DHHC pfam01529
DHHC palmitoyltransferase; This entry refers to the DHHC domain, found in DHHC proteins which ...
 293-429 1.95e-32

DHHC palmitoyltransferase; This entry refers to the DHHC domain, found in DHHC proteins which are palmitoyltransferases. Palmitoylation or, more specifically S-acylation, plays important roles in the regulation of protein localization, stability, and activity. It is a post-translational protein modification that involves the attachment of palmitic acid to Cys residues through a thioester linkage. Protein acyltransferases (PATs), also known as palmitoyltransferases, catalyze this reaction by transferring the palmitoyl group from palmitoyl-CoA to the thiol group of Cys residues. They are characterized by the presence of a 50-residue-long domain called the DHHC domain, which in most but not all cases is also cysteine-rich and gets its name from a highly conserved DHHC signature tetrapeptide (Asp-His-His-Cys). The Cys residue within the DHHC domain forms a stable acyl intermediate and transfers the acyl chain to the Cys residues of a target protein. Some proteins containing a DHHC domain include Drosophila DNZ1 protein, Mouse Abl-philin 2 (Aph2) protein, Mammalian ZDHHC9, Yeast ankyrin repeat-containing protein AKR1, Yeast Erf2 protein, and Arabidopsis thaliana tip growth defective 1.


Pssm-ID: 396215  Cd Length: 132  Bit Score: 120.16  E-value: 1.95e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108  293 DFRTFCTSCLIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFK 372
Cdd:pfam01529   3 DELKYCSTCNIYKPPRSKHCRVCNRCVLRFDHHCPWLNNCIGKRNHKYFILFLLYLTLYLILYLVLSLYYLVKLIESSTL 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767966108  373 EDGLWTYLNQivacspWVLYILMLATFHFSWSTFLLLNQLFQIaFLGLTSHERISLQ 429
Cdd:pfam01529  83 FFFLILFLFS------ISIILLILSLFFLLFLGILLFFHLYLI-SRNLTTYEFMKKK 132
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
1-140 1.23e-29

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 117.75  E-value: 1.23e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKviG-PEPTGFLLKFNPSL 79
Cdd:COG0666  102 IVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAAN--GnLEIVKLLLEAGADV 179

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767966108  80 NVVDKiHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHMLK 140
Cdd:COG0666  180 NARDN-DGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLL 239
COG5273 COG5273
Uncharacterized protein containing DHHC-type Zn finger [General function prediction only];
211-458 1.75e-24

Uncharacterized protein containing DHHC-type Zn finger [General function prediction only];


Pssm-ID: 227598 [Multi-domain]  Cd Length: 309  Bit Score: 103.29  E-value: 1.75e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108 211 YKNLVYLPTAFLLSSVFWIFMTwFILFFPDLAGAPFYFSFIFSIVAFLYFFYKTwaTDPGFTKASEEEKKVN--IITLAE 288
Cdd:COG5273   26 YAYKMFIGLFLLSRIVVYTLLV-IVKSLSLVVLFIILFIVILVLASFSYLLLLV--SDPGYLGENITLSGYRetISRLLD 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108 289 TGSLDFRTFCTSCLIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVcgwIIYgSFIYLSSHCA 368
Cdd:COG5273  103 DGKFGTENFCSTCNIYKPPRSHHCSICNRCVLKFDHHCPWINNCVGFRNYRFFYQFLLYTILV---ALV-VLLSTAYYIA 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108 369 TTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSW--STFLLLNQLFQIAFL-----GLTSHERISLQKQSKHMKQTLSL 441
Cdd:COG5273  179 GIFSIRHDTSLAICFLIFGCSLLGVVFFIITTLLLlfLIYLILNNLTTIEFIqisrgGSTLEFFPLCRESNLPFTNIFDS 258

                        250
                 ....*....|....*....
gi 767966108 442 RKT--PYNLGFMQNLADFF 458
Cdd:COG5273  259 SEGalPLDLGIGQNLSTIK 277
Ank_2 pfam12796
Ankyrin repeats (3 copies);
23-117 2.31e-13

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 65.52  E-value: 2.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   23 IHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKvigpeptG------FLLKFNpslNVVDKIHQNTPLHWAVA 96
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKN-------GhleivkLLLEHA---DVNLKDNGRTALHYAAR 70

                          90       100
                  ....*....|....*....|.
gi 767966108   97 AGNVNAVDKLLEAGSSLDIQN 117
Cdd:pfam12796  71 SGHLEIVKLLLEKGADINVKD 91
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 1-139 4.36e-12

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 67.77  E-value: 4.36e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQH--MPIIAYLISKGQSVN-MTDVNgqtplmlsahkvigpeptgFLLKFNP 77
Cdd:PHA03100 123 IVEYLLDNGANVNIKNSDGENLLHLYLESNKidLKILKLLIDKGVDINaKNRVN-------------------YLLSYGV 183

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767966108  78 SLNVVDKIHqNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHML 139
Cdd:PHA03100 184 PINIKDVYG-FTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLL 244
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 86-115 1.11e-03

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 36.41  E-value: 1.11e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 767966108    86 HQNTPLHWAVAAGNVNAVDKLLEAGSSLDI 115
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
 
Name Accession Description Interval E-value
DHHC pfam01529
DHHC palmitoyltransferase; This entry refers to the DHHC domain, found in DHHC proteins which ...
 293-429 1.95e-32

DHHC palmitoyltransferase; This entry refers to the DHHC domain, found in DHHC proteins which are palmitoyltransferases. Palmitoylation or, more specifically S-acylation, plays important roles in the regulation of protein localization, stability, and activity. It is a post-translational protein modification that involves the attachment of palmitic acid to Cys residues through a thioester linkage. Protein acyltransferases (PATs), also known as palmitoyltransferases, catalyze this reaction by transferring the palmitoyl group from palmitoyl-CoA to the thiol group of Cys residues. They are characterized by the presence of a 50-residue-long domain called the DHHC domain, which in most but not all cases is also cysteine-rich and gets its name from a highly conserved DHHC signature tetrapeptide (Asp-His-His-Cys). The Cys residue within the DHHC domain forms a stable acyl intermediate and transfers the acyl chain to the Cys residues of a target protein. Some proteins containing a DHHC domain include Drosophila DNZ1 protein, Mouse Abl-philin 2 (Aph2) protein, Mammalian ZDHHC9, Yeast ankyrin repeat-containing protein AKR1, Yeast Erf2 protein, and Arabidopsis thaliana tip growth defective 1.


Pssm-ID: 396215  Cd Length: 132  Bit Score: 120.16  E-value: 1.95e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108  293 DFRTFCTSCLIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFK 372
Cdd:pfam01529   3 DELKYCSTCNIYKPPRSKHCRVCNRCVLRFDHHCPWLNNCIGKRNHKYFILFLLYLTLYLILYLVLSLYYLVKLIESSTL 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767966108  373 EDGLWTYLNQivacspWVLYILMLATFHFSWSTFLLLNQLFQIaFLGLTSHERISLQ 429
Cdd:pfam01529  83 FFFLILFLFS------ISIILLILSLFFLLFLGILLFFHLYLI-SRNLTTYEFMKKK 132
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
1-140 1.23e-29

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 117.75  E-value: 1.23e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKviG-PEPTGFLLKFNPSL 79
Cdd:COG0666  102 IVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAAN--GnLEIVKLLLEAGADV 179

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767966108  80 NVVDKiHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHMLK 140
Cdd:COG0666  180 NARDN-DGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLL 239
COG5273 COG5273
Uncharacterized protein containing DHHC-type Zn finger [General function prediction only];
211-458 1.75e-24

Uncharacterized protein containing DHHC-type Zn finger [General function prediction only];


Pssm-ID: 227598 [Multi-domain]  Cd Length: 309  Bit Score: 103.29  E-value: 1.75e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108 211 YKNLVYLPTAFLLSSVFWIFMTwFILFFPDLAGAPFYFSFIFSIVAFLYFFYKTwaTDPGFTKASEEEKKVN--IITLAE 288
Cdd:COG5273   26 YAYKMFIGLFLLSRIVVYTLLV-IVKSLSLVVLFIILFIVILVLASFSYLLLLV--SDPGYLGENITLSGYRetISRLLD 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108 289 TGSLDFRTFCTSCLIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVcgwIIYgSFIYLSSHCA 368
Cdd:COG5273  103 DGKFGTENFCSTCNIYKPPRSHHCSICNRCVLKFDHHCPWINNCVGFRNYRFFYQFLLYTILV---ALV-VLLSTAYYIA 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108 369 TTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSW--STFLLLNQLFQIAFL-----GLTSHERISLQKQSKHMKQTLSL 441
Cdd:COG5273  179 GIFSIRHDTSLAICFLIFGCSLLGVVFFIITTLLLlfLIYLILNNLTTIEFIqisrgGSTLEFFPLCRESNLPFTNIFDS 258

                        250
                 ....*....|....*....
gi 767966108 442 RKT--PYNLGFMQNLADFF 458
Cdd:COG5273  259 SEGalPLDLGIGQNLSTIK 277
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
1-150 1.81e-21

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 94.25  E-value: 1.81e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKviG-PEPTGFLLKFNPSL 79
Cdd:COG0666  135 IVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAEN--GhLEIVKLLLEAGADV 212

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767966108  80 NVVDKiHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHMLKTEAKMRANQK 150
Cdd:COG0666  213 NAKDN-DGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAAL 282
Ank_2 pfam12796
Ankyrin repeats (3 copies);
23-117 2.31e-13

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 65.52  E-value: 2.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   23 IHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKvigpeptG------FLLKFNpslNVVDKIHQNTPLHWAVA 96
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKN-------GhleivkLLLEHA---DVNLKDNGRTALHYAAR 70

                          90       100
                  ....*....|....*....|.
gi 767966108   97 AGNVNAVDKLLEAGSSLDIQN 117
Cdd:pfam12796  71 SGHLEIVKLLLEKGADINVKD 91
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 1-139 4.36e-12

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 67.77  E-value: 4.36e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQH--MPIIAYLISKGQSVN-MTDVNgqtplmlsahkvigpeptgFLLKFNP 77
Cdd:PHA03100 123 IVEYLLDNGANVNIKNSDGENLLHLYLESNKidLKILKLLIDKGVDINaKNRVN-------------------YLLSYGV 183

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767966108  78 SLNVVDKIHqNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHML 139
Cdd:PHA03100 184 PINIKDVYG-FTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLL 244
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 1-130 2.90e-11

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 65.86  E-value: 2.90e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNgqtplMLSAHKVIGPEPTGFLLKFNPSLN 80
Cdd:PHA02876 193 MVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNINKNDLS-----LLKAIRNEDLETSLLLYDAGFSVN 267

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767966108  81 VVDkIHQNTPLHWAVAAGNVNA-VDKLLEAGSSLDIQNVKGETPLDMALQN 130
Cdd:PHA02876 268 SID-DCKNTPLHHASQAPSLSRlVPKLLERGADVNAKNIKGETPLYLMAKN 317
PHA03095 PHA03095
ankyrin-like protein; Provisional
 1-132 6.56e-11

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 64.28  E-value: 6.56e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHlavlfQHM-------PIIAYLISKGQSVNMTDVNGQTPLMLSA------HKVIGPe 67
Cdd:PHA03095 169 LLRLLIDAGADVYAVDDRFRSLLH-----HHLqsfkpraRIVRELIRAGCDPAATDMLGNTPLHSMAtgssckRSLVLP- 242

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767966108  68 ptgFLLKfNPSLNVVDKIHQnTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKN 132
Cdd:PHA03095 243 ---LLIA-GISINARNRYGQ-TPLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMVRNNN 302
PHA03095 PHA03095
ankyrin-like protein; Provisional
 2-139 9.18e-11

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 63.89  E-value: 9.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   2 VILLLQHGADPTLIDGEGFSSIHLAVLFQH-MPIIAYLISKGQSVNMTDVNGQTPlmLSAH---KVIGPEPTGFLLKFNP 77
Cdd:PHA03095  66 VRLLLEAGADVNAPERCGFTPLHLYLYNATtLDVIKLLIKAGADVNAKDKVGRTP--LHVYlsgFNINPKVIRLLLRKGA 143

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767966108  78 SLNVVDKiHQNTPLHWAVAAGNVNA--VDKLLEAGSSLDIQNVKGETPLDMALQN--KNQLIIHML 139
Cdd:PHA03095 144 DVNALDL-YGMTPLAVLLKSRNANVelLRLLIDAGADVYAVDDRFRSLLHHHLQSfkPRARIVREL 208
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
1-139 4.76e-10

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 60.74  E-value: 4.76e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLN 80
Cdd:COG0666    2 LLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADIN 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 767966108  81 VVDKiHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHML 139
Cdd:COG0666   82 AKDD-GGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLL 139
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 1-132 3.14e-09

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 58.91  E-value: 3.14e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQH-----MPIIAYLISKGQSVNMTDVNGQTPLMLSAHKVIG-PEPTGFLLK 74
Cdd:PHA03100  50 VVKILLDNGADINSSTKNNSTPLHYLSNIKYnltdvKEIVKLLLEYGANVNAPDNNGITPLLYAISKKSNsYSIVEYLLD 129

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767966108  75 FNPSLNVVDKIHQNtPLHWAVAAG---------------NVNA---VDKLLEAGSSLDIQNVKGETPLDMALQNKN 132
Cdd:PHA03100 130 NGANVNIKNSDGEN-LLHLYLESNkidlkilkllidkgvDINAknrVNYLLSYGVPINIKDVYGFTPLHYAVYNNN 204
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 4-128 7.60e-09

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 57.97  E-value: 7.60e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   4 LLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLNVVD 83
Cdd:PHA02878 186 LLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYCKDYDILKLLLEHGVDVNAKS 265

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 767966108  84 KIHQNTPLHWAVAAGNVnaVDKLLEAGSSLDIQNVKGETPLDMAL 128
Cdd:PHA02878 266 YILGLTALHSSIKSERK--LKLLLEYGADINSLNSYKLTPLSSAV 308
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 2-134 9.26e-09

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 57.28  E-value: 9.26e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   2 VILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPL----------------------MLS 59
Cdd:PHA02874 140 IKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLhnaaeygdyacikllidhgnhiMNK 219

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108  60 AHKVIGPEPTGF--------LLKFNPSLNVVDkIHQNTPLHWAVA-AGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQN 130
Cdd:PHA02874 220 CKNGFTPLHNAIihnrsaieLLINNASINDQD-IDGSTPLHHAINpPCDIDIIDILLYHKADISIKDNKGENPIDTAFKY 298


                 ....
gi 767966108 131 KNQL 134
Cdd:PHA02874 299 INKD 302
PHA03095 PHA03095
ankyrin-like protein; Provisional
 1-127 1.44e-08

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 56.96  E-value: 1.44e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFS--SIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPL--MLSAHKV----------IGP 66
Cdd:PHA03095  99 VIKLLIKAGADVNAKDKVGRTplHVYLSGFNINPKVIRLLLRKGADVNALDLYGMTPLavLLKSRNAnvellrllidAGA 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108  67 EPTG-----------FLLKFNPSLNVVDKI------------HQNTPLHWAVAAGNVNA--VDKLLEAGSSLDIQNVKGE 121
Cdd:PHA03095 179 DVYAvddrfrsllhhHLQSFKPRARIVRELiragcdpaatdmLGNTPLHSMATGSSCKRslVLPLLIAGISINARNRYGQ 258


                 ....*.
gi 767966108 122 TPLDMA 127
Cdd:PHA03095 259 TPLHYA 264
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 26-148 2.65e-08

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 55.77  E-value: 2.65e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108  26 AVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLsAHKVIGPEPTGFLLKFN--PSLNVVDkihQNTPLHWAVAAGNVNAV 103
Cdd:PHA02875   9 AILFGELDIARRLLDIGINPNFEIYDGISPIKL-AMKFRDSEAIKLLMKHGaiPDVKYPD---IESELHDAVEEGDVKAV 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 767966108 104 DKLLEAGSSL-DIQNVKGETPLDMALQNKNqliIHMLKTEAKMRAN 148
Cdd:PHA02875  85 EELLDLGKFAdDVFYKDGMTPLHLATILKK---LDIMKLLIARGAD 127
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 1-139 4.90e-08

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 55.00  E-value: 4.90e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNmtDV---NGQTPLMLsAHKVIGPEPTGFLLKF-- 75
Cdd:PHA02875  50 AIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEELLDLGKFAD--DVfykDGMTPLHL-ATILKKLDIMKLLIARga 126

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767966108  76 NPSLNVVDKIhqnTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHML 139
Cdd:PHA02875 127 DPDIPNTDKF---SPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKML 187
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 1-134 1.07e-07

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 54.12  E-value: 1.07e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLID-GEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLmlsaHKVI---GPEPTGFLLKFN 76
Cdd:PHA02878 149 ITKLLLSYGADINMKDrHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPL----HHAVkhyNKPIVHILLENG 224

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108  77 PSLNVVDKiHQNTPLHWAVAA-GNVNAVDKLLEAGSSLDIQN-VKGETPLDMALQNKNQL 134
Cdd:PHA02878 225 ASTDARDK-CGNTPLHISVGYcKDYDILKLLLEHGVDVNAKSyILGLTALHSSIKSERKL 283
Ank_5 pfam13857
Ankyrin repeats (many copies);
72-127 1.35e-07

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 48.11  E-value: 1.35e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767966108   72 LLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMA 127
Cdd:pfam13857   1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 3-139 1.86e-06

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 50.45  E-value: 1.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   3 ILLLQHGADPTLIDGEGFSSIHLAVLFQHMP-IIAYLISKGQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLNV 81
Cdd:PHA02876 257 LLLYDAGFSVNSIDDCKNTPLHHASQAPSLSrLVPKLLERGADVNAKNIKGETPLYLMAKNGYDTENIRTLIMLGADVNA 336

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 767966108  82 VDKIHqNTPLHWAVAAG-NVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHML 139
Cdd:PHA02876 337 ADRLY-ITPLHQASTLDrNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTL 394
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 1-128 2.44e-06

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 49.96  E-value: 2.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLsAHKVIGPEPTGFLLKFNPSLN 80
Cdd:PHA02874 106 MIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHI-AIKHNFFDIIKLLLEKGAYAN 184

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 767966108  81 VVDKiHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMAL 128
Cdd:PHA02874 185 VKDN-NGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAI 231
Ank_4 pfam13637
Ankyrin repeats (many copies);
87-139 6.20e-06

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 43.42  E-value: 6.20e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767966108   87 QNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHML 139
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
Ank_5 pfam13857
Ankyrin repeats (many copies);
5-56 2.20e-05

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 41.95  E-value: 2.20e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767966108    5 LLQHG-ADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPL 56
Cdd:pfam13857   1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTAL 53
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 1-126 2.90e-05

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 46.52  E-value: 2.90e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLS-AHKVIgpEPTGFLLKFNPSL 79
Cdd:PHA02875 117 IMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAmAKGDI--AICKMLLDSGANI 194

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 767966108  80 NVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQ-NVKGE--TPLDM 126
Cdd:PHA02875 195 DYFGKNGCVAALCYAIENNKIDIVRLFIKRGADCNIMfMIEGEecTILDM 244
Ank_2 pfam12796
Ankyrin repeats (3 copies);
91-139 5.35e-05

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 42.03  E-value: 5.35e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 767966108   91 LHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHML 139
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLL 49
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 86-117 2.79e-04

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 38.04  E-value: 2.79e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 767966108   86 HQNTPLHWAVA-AGNVNAVDKLLEAGSSLDIQN 117
Cdd:pfam00023   1 DGNTPLHLAAGrRGNLEIVKLLLSKGADVNARD 33
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 4-59 6.08e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 42.58  E-value: 6.08e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 767966108   4 LLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLS 59
Cdd:PTZ00322 100 ILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELA 155
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 86-115 1.11e-03

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 36.41  E-value: 1.11e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 767966108    86 HQNTPLHWAVAAGNVNAVDKLLEAGSSLDI 115
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
PHA03095 PHA03095
ankyrin-like protein; Provisional
 34-132 1.92e-03

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 40.78  E-value: 1.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108  34 IIAYLISKGQSVNMTDVNGQTPLMLSAHKVIGPEP--TGFLLKFNPSLNVVDkIHQNTPLHWAVAAGNVNAVDKLL-EAG 110
Cdd:PHA03095  29 EVRRLLAAGADVNFRGEYGKTPLHLYLHYSSEKVKdiVRLLLEAGADVNAPE-RCGFTPLHLYLYNATTLDVIKLLiKAG 107

                         90       100
                 ....*....|....*....|..
gi 767966108 111 SSLDIQNVKGETPLDMALQNKN 132
Cdd:PHA03095 108 ADVNAKDKVGRTPLHVYLSGFN 129
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 86-139 2.27e-03

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 40.65  E-value: 2.27e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 767966108  86 HQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHML 139
Cdd:PTZ00322 114 DGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLL 167
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 1-132 2.45e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 40.43  E-value: 2.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966108   1 MVILLLQHGADPTLIDGEGFSSIHLAVLFQH-MPIIAYLISKGQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSL 79
Cdd:PHA02876 289 LVPKLLERGADVNAKNIKGETPLYLMAKNGYdTENIRTLIMLGADVNAADRLYITPLHQASTLDRNKDIVITLLELGANV 368

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 767966108  80 NVVDkIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKN 132
Cdd:PHA02876 369 NARD-YCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFALCGTN 420
Ank_4 pfam13637
Ankyrin repeats (many copies);
21-62 3.17e-03

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 35.71  E-value: 3.17e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 767966108   21 SSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHK 62
Cdd:pfam13637   3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASN 44
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 63-139 3.20e-03

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 39.86  E-value: 3.20e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767966108  63 VIGPEPTGFLLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHML 139
Cdd:PHA02878 144 IIEAEITKLLLSYGADINMKDRHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHIL 220
Ank_4 pfam13637
Ankyrin repeats (many copies);
4-39 3.33e-03

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 35.71  E-value: 3.33e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 767966108    4 LLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLI 39
Cdd:pfam13637  19 LLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
Ank_2 pfam12796
Ankyrin repeats (3 copies);
1-49 4.66e-03

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 36.25  E-value: 4.66e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 767966108    1 MVILLLQHGAdpTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTD 49
Cdd:pfam12796  45 IVKLLLEHAD--VNLKDNGRTALHYAARSGHLEIVKLLLEKGADINVKD 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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