NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|767966098|ref|XP_011518492|]
View 

cadherin-related family member 5 isoform X5 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 274-343 3.60e-10

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 56.94  E-value: 3.60e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767966098 274 IYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVP--SPMTFLLLVKGQ-QADLARYSVTQVTVE 343
Cdd:cd11304   19 VSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDreEQSSYTLTVTATdGGGPPLSSTATVTIT 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 37-120 2.76e-06

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 45.77  E-value: 2.76e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098  37 FEVEENTNVTEPLVDIHV-----PEGQEVT--LGALSTPFAFRIQGN--QLFLNVTPDYEEKSLLEAQLLCQSGGT--LV 105
Cdd:cd11304    4 VSVPENAPPGTVVLTVSAtdpdsGENGEVTysIVSGNEDGLFSIDPStgEITTAKPLDREEQSSYTLTVTATDGGGppLS 83

                         90
                 ....*....|....*
gi 767966098 106 TQLRVFVSVLDVNDN 120
Cdd:cd11304   84 STATVTITVLDVNDN 98
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
463-549 7.16e-05

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK12323:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 700  Bit Score: 45.64  E-value: 7.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098 463 ASPSLSTSTMAPGSSAAVAKLRSPSPKALTTRRSSLTTRPTGRPSPAPRTTPSPRRHRCPQSPHPPALPPQAVPLSPPQR 542
Cdd:PRK12323 405 APAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAA 484


                 ....*..
gi 767966098 543 PELAEAP 549
Cdd:PRK12323 485 PAAAPAP 491
Cadherin_3 super family cl28802
Cadherin-like;
110-165 3.40e-03

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 37.58  E-value: 3.40e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767966098  110 VFVSVLDVNDNAPEfPFKTKEIRVEEDTkvnSTVIPETQLQAEDRD--KDDILFYTLQ 165
Cdd:pfam16184   7 FNITIIPVNDEAPV-LTTNTGLRLWEGS---SRPITPDLLQAEDPDtpPEDLTYTVVQ 60
CA_like super family cl46864
Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 150-228 9.23e-03

Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers. This family also includes the cadherin-like repeats of extracellular alpha-dystroglycan.


The actual alignment was detected with superfamily member smart00112:

Pssm-ID: 481204 [Multi-domain]  Cd Length: 81  Bit Score: 35.40  E-value: 9.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098   150 QAEDRDKDD--ILFYTLQEmtAGASDYFSLVSVNRpALRLDRPLDFYERPNMTFWLLVRDtpgeNVEPSHTATATLVLNV 227
Cdd:smart00112   1 SATDADSGEngKVTYSILS--GNDDGLFSIDPETG-EITTTKPLDREEQPEYTLTVEATD----GGGPPLSSTATVTITV 73


                   .
gi 767966098   228 V 228
Cdd:smart00112  74 L 74
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 274-343 3.60e-10

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 56.94  E-value: 3.60e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767966098 274 IYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVP--SPMTFLLLVKGQ-QADLARYSVTQVTVE 343
Cdd:cd11304   19 VSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDreEQSSYTLTVTATdGGGPPLSSTATVTIT 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 276-314 8.38e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 46.96  E-value: 8.38e-07
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 767966098   276 AEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARS 314
Cdd:smart00112   2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKP 40
Cadherin pfam00028
Cadherin domain;
253-343 1.60e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 46.52  E-value: 1.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098  253 YHGAVPTGhILPSPLVLRpgpIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSV--PSPMTFLLLVKGQQA 330
Cdd:pfam00028   1 YSASVPEN-APVGTEVLT---VTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLdrESIGEYELTVEATDS 76

                          90
                  ....*....|....
gi 767966098  331 DL-ARYSVTQVTVE 343
Cdd:pfam00028  77 GGpPLSSTATVTIT 90
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 37-120 2.76e-06

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 45.77  E-value: 2.76e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098  37 FEVEENTNVTEPLVDIHV-----PEGQEVT--LGALSTPFAFRIQGN--QLFLNVTPDYEEKSLLEAQLLCQSGGT--LV 105
Cdd:cd11304    4 VSVPENAPPGTVVLTVSAtdpdsGENGEVTysIVSGNEDGLFSIDPStgEITTAKPLDREEQSSYTLTVTATDGGGppLS 83

                         90
                 ....*....|....*
gi 767966098 106 TQLRVFVSVLDVNDN 120
Cdd:cd11304   84 STATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 71-122 8.20e-06

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 43.88  E-value: 8.20e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767966098    71 FRI--QGNQLFLNVTPDYEEKSLLEAQLLCQSGGT--LVTQLRVFVSVLDVNDNAP 122
Cdd:smart00112  26 FSIdpETGEITTTKPLDREEQPEYTLTVEATDGGGppLSSTATVTITVLDVNDNAP 81
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
463-549 7.16e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.64  E-value: 7.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098 463 ASPSLSTSTMAPGSSAAVAKLRSPSPKALTTRRSSLTTRPTGRPSPAPRTTPSPRRHRCPQSPHPPALPPQAVPLSPPQR 542
Cdd:PRK12323 405 APAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAA 484


                 ....*..
gi 767966098 543 PELAEAP 549
Cdd:PRK12323 485 PAAAPAP 491
Cadherin_3 pfam16184
Cadherin-like;
110-165 3.40e-03

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 37.58  E-value: 3.40e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767966098  110 VFVSVLDVNDNAPEfPFKTKEIRVEEDTkvnSTVIPETQLQAEDRD--KDDILFYTLQ 165
Cdd:pfam16184   7 FNITIIPVNDEAPV-LTTNTGLRLWEGS---SRPITPDLLQAEDPDtpPEDLTYTVVQ 60
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 468-550 3.93e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 40.36  E-value: 3.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098   468 STSTMAPGSSAAvAKLRSPSPK--ALTTRRSSLTTRP-TGRPSPAPRTTPSPR--------RHRC---------PQSPHP 527
Cdd:TIGR00927  333 SSPAETKASTAA-WKIRNPLSRtsAPAVRIASATFRGlEKNPSTAPSTPATPRvravlttqVHHCvvvkpapavPTTPSP 411

                           90       100       110
                   ....*....|....*....|....*....|...
gi 767966098   528 -------PALPPQAVPLSPPQRPEL---AEAPR 550
Cdd:TIGR00927  412 slttalfPEAPSPSPSALPPGQPDLhpkAEYPP 444
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 150-228 9.23e-03

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 35.40  E-value: 9.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098   150 QAEDRDKDD--ILFYTLQEmtAGASDYFSLVSVNRpALRLDRPLDFYERPNMTFWLLVRDtpgeNVEPSHTATATLVLNV 227
Cdd:smart00112   1 SATDADSGEngKVTYSILS--GNDDGLFSIDPETG-EITTTKPLDREEQPEYTLTVEATD----GGGPPLSSTATVTITV 73


                   .
gi 767966098   228 V 228
Cdd:smart00112  74 L 74
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 274-343 3.60e-10

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 56.94  E-value: 3.60e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767966098 274 IYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVP--SPMTFLLLVKGQ-QADLARYSVTQVTVE 343
Cdd:cd11304   19 VSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDreEQSSYTLTVTATdGGGPPLSSTATVTIT 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 276-314 8.38e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 46.96  E-value: 8.38e-07
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 767966098   276 AEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARS 314
Cdd:smart00112   2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKP 40
Cadherin pfam00028
Cadherin domain;
253-343 1.60e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 46.52  E-value: 1.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098  253 YHGAVPTGhILPSPLVLRpgpIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSV--PSPMTFLLLVKGQQA 330
Cdd:pfam00028   1 YSASVPEN-APVGTEVLT---VTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLdrESIGEYELTVEATDS 76

                          90
                  ....*....|....
gi 767966098  331 DL-ARYSVTQVTVE 343
Cdd:pfam00028  77 GGpPLSSTATVTIT 90
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 37-120 2.76e-06

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 45.77  E-value: 2.76e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098  37 FEVEENTNVTEPLVDIHV-----PEGQEVT--LGALSTPFAFRIQGN--QLFLNVTPDYEEKSLLEAQLLCQSGGT--LV 105
Cdd:cd11304    4 VSVPENAPPGTVVLTVSAtdpdsGENGEVTysIVSGNEDGLFSIDPStgEITTAKPLDREEQSSYTLTVTATDGGGppLS 83

                         90
                 ....*....|....*
gi 767966098 106 TQLRVFVSVLDVNDN 120
Cdd:cd11304   84 STATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 71-122 8.20e-06

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 43.88  E-value: 8.20e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767966098    71 FRI--QGNQLFLNVTPDYEEKSLLEAQLLCQSGGT--LVTQLRVFVSVLDVNDNAP 122
Cdd:smart00112  26 FSIdpETGEITTTKPLDREEQPEYTLTVEATDGGGppLSSTATVTITVLDVNDNAP 81
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
463-549 7.16e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.64  E-value: 7.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098 463 ASPSLSTSTMAPGSSAAVAKLRSPSPKALTTRRSSLTTRPTGRPSPAPRTTPSPRRHRCPQSPHPPALPPQAVPLSPPQR 542
Cdd:PRK12323 405 APAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAA 484


                 ....*..
gi 767966098 543 PELAEAP 549
Cdd:PRK12323 485 PAAAPAP 491
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 473-550 3.10e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.91  E-value: 3.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098 473 APGSSAAVAKLRSPSP--KALTTRRSSLTTRPTG-RPSPAPRTTPSPRRHRCPQSPHPPALPPQavplspPQRPELAEAP 549
Cdd:PTZ00449 548 KPGETKEGEVGKKPGPakEHKPSKIPTLSKKPEFpKDPKHPKDPEEPKKPKRPRSAQRPTRPKS------PKLPELLDIP 621


                 .
gi 767966098 550 R 550
Cdd:PTZ00449 622 K 622
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 465-550 4.80e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.14  E-value: 4.80e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098 465 PSLSTSTMAPGSSAAVAKLRSP-SPKALTTrrsslTTRPTGRPSPA-------PRTTPSPRRHRCPQSPHPPALPpqavp 536
Cdd:PTZ00449 573 PTLSKKPEFPKDPKHPKDPEEPkKPKRPRS-----AQRPTRPKSPKlpelldiPKSPKRPESPKSPKRPPPPQRP----- 642

                         90
                 ....*....|....
gi 767966098 537 lSPPQRPELAEAPR 550
Cdd:PTZ00449 643 -SSPERPEGPKIIK 655
PHA03247 PHA03247
large tegument protein UL36; Provisional
 463-551 7.57e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 7.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098  463 ASPSLSTSTMAPgssAAVAKLRSPSPKALTTRRS-----SLTTRPTGRPSPA-PRTTPSPRRHRCPQSPHPPALPPQAVP 536
Cdd:PHA03247 2825 AGPLPPPTSAQP---TAPPPPPGPPPPSLPLGGSvapggDVRRRPPSRSPAAkPAAPARPPVRRLARPAVSRSTESFALP 2901

                          90
                  ....*....|....*
gi 767966098  537 LSPPQRPELAEAPRR 551
Cdd:PHA03247 2902 PDQPERPPQPQAPPP 2916
PHA03247 PHA03247
large tegument protein UL36; Provisional
 461-551 3.16e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 3.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098  461 SLASPSLSTSTMAPGSSAAVAKLR----SPSPKALTTRRSSLTTRPTGRPSPAPRTTPSPRRHRCPQSPHPPALPPQAVP 536
Cdd:PHA03247 2840 PPPPGPPPPSLPLGGSVAPGGDVRrrppSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQP 2919

                          90
                  ....*....|....*
gi 767966098  537 LSPPQRPELAEAPRR 551
Cdd:PHA03247 2920 QPQPPPPPQPQPPPP 2934
Cadherin_3 pfam16184
Cadherin-like;
110-165 3.40e-03

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 37.58  E-value: 3.40e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767966098  110 VFVSVLDVNDNAPEfPFKTKEIRVEEDTkvnSTVIPETQLQAEDRD--KDDILFYTLQ 165
Cdd:pfam16184   7 FNITIIPVNDEAPV-LTTNTGLRLWEGS---SRPITPDLLQAEDPDtpPEDLTYTVVQ 60
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 468-550 3.93e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 40.36  E-value: 3.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098   468 STSTMAPGSSAAvAKLRSPSPK--ALTTRRSSLTTRP-TGRPSPAPRTTPSPR--------RHRC---------PQSPHP 527
Cdd:TIGR00927  333 SSPAETKASTAA-WKIRNPLSRtsAPAVRIASATFRGlEKNPSTAPSTPATPRvravlttqVHHCvvvkpapavPTTPSP 411

                           90       100       110
                   ....*....|....*....|....*....|...
gi 767966098   528 -------PALPPQAVPLSPPQRPEL---AEAPR 550
Cdd:TIGR00927  412 slttalfPEAPSPSPSALPPGQPDLhpkAEYPP 444
PHA03378 PHA03378
EBNA-3B; Provisional
 479-551 4.25e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 40.05  E-value: 4.25e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767966098 479 AVAKLRSPSPKALTTRrsslTTRPTGRPSPAPRTTPSPRRHRCPQSPHPPALPPQAVP--LSPPQRPELAEAPRR 551
Cdd:PHA03378 718 AAATGRARPPAAAPGR----ARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPgaPTPQPPPQAPPAPQQ 788
PHA03378 PHA03378
EBNA-3B; Provisional
 465-551 5.22e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 39.67  E-value: 5.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098 465 PSLSTSTMAPgssAAVAKLRSPSPKALTTRRSslttRPTGRPSPAPRTTPSPRRHRCPQSPHPPALPPQAVPlSPPQRPE 544
Cdd:PHA03378 687 IQWAPGTMQP---PPRAPTPMRPPAAPPGRAQ----RPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAP-GRARPPA 758


                 ....*..
gi 767966098 545 LAEAPRR 551
Cdd:PHA03378 759 AAPGRAR 765
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 461-551 7.09e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 39.38  E-value: 7.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098  461 SLASPSLSTSTMAPGSSAAVAKLR--SPSPKALTTRRSSLTTRPTGRPSPAPRTTPSPRRHRCPQSPHPPAlPPQAVPLS 538
Cdd:PHA03307  307 PAPSSPRASSSSSSSRESSSSSTSssSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSS-PAASAGRP 385

                          90
                  ....*....|...
gi 767966098  539 PPQRPELAEAPRR 551
Cdd:PHA03307  386 TRRRARAAVAGRA 398
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 150-228 9.23e-03

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 35.40  E-value: 9.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767966098   150 QAEDRDKDD--ILFYTLQEmtAGASDYFSLVSVNRpALRLDRPLDFYERPNMTFWLLVRDtpgeNVEPSHTATATLVLNV 227
Cdd:smart00112   1 SATDADSGEngKVTYSILS--GNDDGLFSIDPETG-EITTTKPLDREEQPEYTLTVEATD----GGGPPLSSTATVTITV 73


                   .
gi 767966098   228 V 228
Cdd:smart00112  74 L 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH