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Conserved domains on  [gi|767945189|ref|XP_011513564|]
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integrator complex subunit 1 isoform X2 [Homo sapiens]

Protein Classification

integrator complex subunit 1( domain architecture ID 10575350)

integrator complex subunit 1 (INTS1), a DUF3677 domain-containing protein, is a component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3677 pfam12432
Protein of unknown function (DUF3677); This domain family is found in eukaryotes, and is ...
 350-430 3.74e-37

Protein of unknown function (DUF3677); This domain family is found in eukaryotes, and is approximately 80 amino acids in length.


:

Pssm-ID: 463578  Cd Length: 81  Bit Score: 134.30  E-value: 3.74e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767945189   350 LLRLLTSTCGYKEVRLLAVQKLEMWLQNPKLTRPAQDLLMSVCMNCNTHGSEDMDVISHLIKIRLKPKVLLNHFMLCIRE 429
Cdd:pfam12432    1 LLKLLSSTCGYPEVRLLAASRLEIWLQNPKLMRPAQELLLSLCVNCNTSAERDVEVIDYLLKMRLKTKPLINHYTACIKE 80


                   .
gi 767945189   430 L 430
Cdd:pfam12432   81 L 81
 
Name Accession Description Interval E-value
DUF3677 pfam12432
Protein of unknown function (DUF3677); This domain family is found in eukaryotes, and is ...
 350-430 3.74e-37

Protein of unknown function (DUF3677); This domain family is found in eukaryotes, and is approximately 80 amino acids in length.


Pssm-ID: 463578  Cd Length: 81  Bit Score: 134.30  E-value: 3.74e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767945189   350 LLRLLTSTCGYKEVRLLAVQKLEMWLQNPKLTRPAQDLLMSVCMNCNTHGSEDMDVISHLIKIRLKPKVLLNHFMLCIRE 429
Cdd:pfam12432    1 LLKLLSSTCGYPEVRLLAASRLEIWLQNPKLMRPAQELLLSLCVNCNTSAERDVEVIDYLLKMRLKTKPLINHYTACIKE 80


                   .
gi 767945189   430 L 430
Cdd:pfam12432   81 L 81
 
Name Accession Description Interval E-value
DUF3677 pfam12432
Protein of unknown function (DUF3677); This domain family is found in eukaryotes, and is ...
 350-430 3.74e-37

Protein of unknown function (DUF3677); This domain family is found in eukaryotes, and is approximately 80 amino acids in length.


Pssm-ID: 463578  Cd Length: 81  Bit Score: 134.30  E-value: 3.74e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767945189   350 LLRLLTSTCGYKEVRLLAVQKLEMWLQNPKLTRPAQDLLMSVCMNCNTHGSEDMDVISHLIKIRLKPKVLLNHFMLCIRE 429
Cdd:pfam12432    1 LLKLLSSTCGYPEVRLLAASRLEIWLQNPKLMRPAQELLLSLCVNCNTSAERDVEVIDYLLKMRLKTKPLINHYTACIKE 80


                   .
gi 767945189   430 L 430
Cdd:pfam12432   81 L 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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