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Conserved domains on  [gi|767939238|ref|XP_011512597|]
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inositol hexakisphosphate kinase 3 isoform X3 [Homo sapiens]

Protein Classification

inositol polyphosphate kinase family protein( domain architecture ID 36967)

inositol polyphosphate kinase family protein similar to inositol hexakisphosphate kinase, which converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5) and 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4

CATH:  1.10.510.50
EC:  2.7.-.-
Gene Ontology:  GO:0032958|GO:0016301|GO:0005524
SCOP:  4002804

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IPK super family cl12283
Inositol polyphosphate kinase; ArgRIII has has been demonstrated to be an inositol ...
 198-256 8.87e-35

Inositol polyphosphate kinase; ArgRIII has has been demonstrated to be an inositol polyphosphate kinase.


The actual alignment was detected with superfamily member pfam03770:

Pssm-ID: 416457  Cd Length: 190  Bit Score: 123.44  E-value: 8.87e-35
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767939238  198 FLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQM 256
Cdd:pfam03770   1 YILLEDLTAGFKKPCVLDLKMGTRTYGDDASEEKRRRQQKKCRETTSASLGFRICGMKV 59
 
Name Accession Description Interval E-value
IPK pfam03770
Inositol polyphosphate kinase; ArgRIII has has been demonstrated to be an inositol ...
 198-256 8.87e-35

Inositol polyphosphate kinase; ArgRIII has has been demonstrated to be an inositol polyphosphate kinase.


Pssm-ID: 397715  Cd Length: 190  Bit Score: 123.44  E-value: 8.87e-35
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767939238  198 FLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQM 256
Cdd:pfam03770   1 YILLEDLTAGFKKPCVLDLKMGTRTYGDDASEEKRRRQQKKCRETTSASLGFRICGMKV 59
PLN02667 PLN02667
inositol polyphosphate multikinase
 199-255 5.01e-14

inositol polyphosphate multikinase


Pssm-ID: 215359  Cd Length: 286  Bit Score: 70.14  E-value: 5.01e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767939238 199 LLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQ 255
Cdd:PLN02667  81 LVLEDLLAGYTKPCVMDVKMGSRTWYPEASEEYIQKCLKKDRETTTVSLGFRVSGFK 137
 
Name Accession Description Interval E-value
IPK pfam03770
Inositol polyphosphate kinase; ArgRIII has has been demonstrated to be an inositol ...
 198-256 8.87e-35

Inositol polyphosphate kinase; ArgRIII has has been demonstrated to be an inositol polyphosphate kinase.


Pssm-ID: 397715  Cd Length: 190  Bit Score: 123.44  E-value: 8.87e-35
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767939238  198 FLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQM 256
Cdd:pfam03770   1 YILLEDLTAGFKKPCVLDLKMGTRTYGDDASEEKRRRQQKKCRETTSASLGFRICGMKV 59
PLN02667 PLN02667
inositol polyphosphate multikinase
 199-255 5.01e-14

inositol polyphosphate multikinase


Pssm-ID: 215359  Cd Length: 286  Bit Score: 70.14  E-value: 5.01e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767939238 199 LLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQ 255
Cdd:PLN02667  81 LVLEDLLAGYTKPCVMDVKMGSRTWYPEASEEYIQKCLKKDRETTTVSLGFRVSGFK 137
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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