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Conserved domains on  [gi|767925775|ref|XP_011510744|]
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leucine-rich repeat-containing protein 34 isoform X1 [Homo sapiens]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1006001)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNA1 super family cl34950
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 133-377 3.01e-32

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


The actual alignment was detected with superfamily member COG5238:

Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 127.60  E-value: 3.01e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 133 NLLCDVGAYYAAKLLQKQLNLIYLnlMFNDIGPEGGELIAKVLH-NRTLKYLRMTGNKIENKGGMFFAAMLQINSSLEKL 211
Cdd:COG5238  164 RLGLLAAISMAKALQNNSVETVYL--GCNQIGDEGIEELAEALTqNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTL 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 212 DLGDCDLGMQSVIAFATVLTQNQAIKAINLN-RPIlyseQEESTVHVGRMLKENHCLVALHMCKHDIKNSGIQQLCDALY 290
Cdd:COG5238  242 DLSNNQIGDEGVIALAEALKNNTTVETLYLSgNQI----GAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQ 317

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 291 LNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTShNRSLKALSVVSNNIEGEGLVAL 370
Cdd:COG5238  318 GNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLEG-NTTLRELNLGKNNIGKQGAEAL 396


                 ....*..
gi 767925775 371 SQSMKTN 377
Cdd:COG5238  397 IDALQTN 403
 
Name Accession Description Interval E-value
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 133-377 3.01e-32

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 127.60  E-value: 3.01e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 133 NLLCDVGAYYAAKLLQKQLNLIYLnlMFNDIGPEGGELIAKVLH-NRTLKYLRMTGNKIENKGGMFFAAMLQINSSLEKL 211
Cdd:COG5238  164 RLGLLAAISMAKALQNNSVETVYL--GCNQIGDEGIEELAEALTqNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTL 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 212 DLGDCDLGMQSVIAFATVLTQNQAIKAINLN-RPIlyseQEESTVHVGRMLKENHCLVALHMCKHDIKNSGIQQLCDALY 290
Cdd:COG5238  242 DLSNNQIGDEGVIALAEALKNNTTVETLYLSgNQI----GAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQ 317

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 291 LNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTShNRSLKALSVVSNNIEGEGLVAL 370
Cdd:COG5238  318 GNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLEG-NTTLRELNLGKNNIGKQGAEAL 396


                 ....*..
gi 767925775 371 SQSMKTN 377
Cdd:COG5238  397 IDALQTN 403
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 147-395 3.60e-28

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 113.60  E-value: 3.60e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 147 LQKQLNLIYLNLMFNDIGPEGGELIAKVLHNRTLKYLRMTGNKIENKGGMFFAAMLQINS-SLEKLDLGDCDLGMQSVIA 225
Cdd:cd00116   77 LTKGCGLQELDLSDNALGPDGCGVLESLLRSSSLQELKLNNNGLGDRGLRLLAKGLKDLPpALEKLVLGRNRLEGASCEA 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 226 FATVLTQNQAikainlnrpilyseqeestvhvgrmlkenhcLVALHMCKHDIKNSGIQQLCDALYLNSSLRYLDVSCNKI 305
Cdd:cd00116  157 LAKALRANRD-------------------------------LKELNLANNGIGDAGIRALAEGLKANCNLEVLDLNNNGL 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 306 THDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTSHNRSLKALSVVSNNIEGEGLVALSQSMKTNLTFSHIYI 385
Cdd:cd00116  206 TDEGASALAETLASLKSLEVLNLGDNNLTDAGAAALASALLSPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLELDL 285

                        250
                 ....*....|
gi 767925775 386 WGNKFDEATC 395
Cdd:cd00116  286 RGNKFGEEGA 295
LRR_8 pfam13855
Leucine rich repeat;
293-362 4.32e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.27  E-value: 4.32e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775  293 SSLRYLDVSCNKITHDGmvylADVLKSNTTLEVIDLSFNRIenagaNYLSETLTSHNRSLKALSVVSNNI 362
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLD----DGAFKGLSNLKVLDLSNNLL-----TTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI smart00368
Leucine rich repeat, ribonuclease inhibitor type;
292-319 4.01e-03

Leucine rich repeat, ribonuclease inhibitor type;


Pssm-ID: 197686 [Multi-domain]  Cd Length: 28  Bit Score: 34.69  E-value: 4.01e-03
                           10        20
                   ....*....|....*....|....*...
gi 767925775   292 NSSLRYLDVSCNKITHDGMVYLADVLKS 319
Cdd:smart00368   1 NPSLRELDLSNNKLGDEGARALAEALKD 28
 
Name Accession Description Interval E-value
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 133-377 3.01e-32

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 127.60  E-value: 3.01e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 133 NLLCDVGAYYAAKLLQKQLNLIYLnlMFNDIGPEGGELIAKVLH-NRTLKYLRMTGNKIENKGGMFFAAMLQINSSLEKL 211
Cdd:COG5238  164 RLGLLAAISMAKALQNNSVETVYL--GCNQIGDEGIEELAEALTqNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTL 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 212 DLGDCDLGMQSVIAFATVLTQNQAIKAINLN-RPIlyseQEESTVHVGRMLKENHCLVALHMCKHDIKNSGIQQLCDALY 290
Cdd:COG5238  242 DLSNNQIGDEGVIALAEALKNNTTVETLYLSgNQI----GAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQ 317

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 291 LNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTShNRSLKALSVVSNNIEGEGLVAL 370
Cdd:COG5238  318 GNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLEG-NTTLRELNLGKNNIGKQGAEAL 396


                 ....*..
gi 767925775 371 SQSMKTN 377
Cdd:COG5238  397 IDALQTN 403
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 174-403 4.08e-29

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 118.74  E-value: 4.08e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 174 VLHN-RTLKYLRMTGNKI-ENKGGMFFAAMLQINSSLEKLDLGDCDLGMQSVIAFATVLTQNQAIKAINLNR-PIlyseQ 250
Cdd:COG5238  146 VLKDpLGGNAVHLLGLAArLGLLAAISMAKALQNNSVETVYLGCNQIGDEGIEELAEALTQNTTVTTLWLKRnPI----G 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 251 EESTVHVGRMLKENHCLVALHMCKHDIKNSGIQQLCDALYLNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSF 330
Cdd:COG5238  222 DEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSV 301

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767925775 331 NRIENAGANYLSETLtSHNRSLKALSVVSNNIEGEGLVALSQSMKTNLTFSHIYIWGNKFDEATCIAYSDLIQ 403
Cdd:COG5238  302 NRIGDEGAIALAEGL-QGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLE 373
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 147-395 3.60e-28

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 113.60  E-value: 3.60e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 147 LQKQLNLIYLNLMFNDIGPEGGELIAKVLHNRTLKYLRMTGNKIENKGGMFFAAMLQINS-SLEKLDLGDCDLGMQSVIA 225
Cdd:cd00116   77 LTKGCGLQELDLSDNALGPDGCGVLESLLRSSSLQELKLNNNGLGDRGLRLLAKGLKDLPpALEKLVLGRNRLEGASCEA 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 226 FATVLTQNQAikainlnrpilyseqeestvhvgrmlkenhcLVALHMCKHDIKNSGIQQLCDALYLNSSLRYLDVSCNKI 305
Cdd:cd00116  157 LAKALRANRD-------------------------------LKELNLANNGIGDAGIRALAEGLKANCNLEVLDLNNNGL 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 306 THDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTSHNRSLKALSVVSNNIEGEGLVALSQSMKTNLTFSHIYI 385
Cdd:cd00116  206 TDEGASALAETLASLKSLEVLNLGDNNLTDAGAAALASALLSPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLELDL 285

                        250
                 ....*....|
gi 767925775 386 WGNKFDEATC 395
Cdd:cd00116  286 RGNKFGEEGA 295
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 125-345 3.57e-25

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 107.18  E-value: 3.57e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 125 INGLDVGYNLLCDVGAYYAAKLLQKQLNLIYLNLMFNDIGPEGGELIAKVL-HNRTLKYLRMTGNKIENKGGMFFAAMLQ 203
Cdd:COG5238  210 VTTLWLKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALkNNTTVETLYLSGNQIGAEGAIALAKALQ 289

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 204 INSSLEKLDLGDCDLGMQSVIAFATVLTQNQAIKAINLNrpilYSE-QEESTVHVGRMLKENHCLVALHMCKHDIKNSGI 282
Cdd:COG5238  290 GNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLA----YNGiGAQGAIALAKALQENTTLHSLDLSDNQIGDEGA 365

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767925775 283 QQLCDALYLNSSLRYLDVSCNKITHDGMVYLADVLKSNtTLEVIDLSFNRIENAGANYLSETL 345
Cdd:COG5238  366 IALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTN-RLHTLILDGNLIGAEAQQRLEQLL 427
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 85-289 1.89e-17

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 84.07  E-value: 1.89e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775  85 KGLAAGITLNIAGNNrlvpverVTGEDFWILSKILKNCLYINGLDVGYNLLCDVGAYYAAKLLQKQLNLIYLNLMFNDIG 164
Cdd:COG5238  233 KGNKSLTTLDLSNNQ-------IGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIG 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 165 PEGGELIAKVL-HNRTLKYLRMTGNKIENKGGMFFAAMLQINSSLEKLDLGDCDLGMQSVIAFATVLTQNQAIKAINLNR 243
Cdd:COG5238  306 DEGAIALAEGLqGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLRELNLGK 385

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 767925775 244 PILYSEQEEStvhVGRMLKENHcLVALHMCKHDIKNSGIQQLCDAL 289
Cdd:COG5238  386 NNIGKQGAEA---LIDALQTNR-LHTLILDGNLIGAEAQQRLEQLL 427
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 208-402 3.65e-11

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 63.91  E-value: 3.65e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 208 LEKLDLGDCDLGMQSVIAFATVLTQNQAIKAINLnRPILYSEQEESTVHVGRMLKENHCLVALhmckhDIKNSGIQ---- 283
Cdd:cd00116   25 LQVLRLEGNTLGEEAAKALASALRPQPSLKELCL-SLNETGRIPRGLQSLLQGLTKGCGLQEL-----DLSDNALGpdgc 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 284 QLCDALYLNSSLRYLDVSCNKITHDGMVYLADVLKSNT-TLEVIDLSFNRIENAGANYLSETLtSHNRSLKALSVVSNNI 362
Cdd:cd00116   99 GVLESLLRSSSLQELKLNNNGLGDRGLRLLAKGLKDLPpALEKLVLGRNRLEGASCEALAKAL-RANRDLKELNLANNGI 177

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 767925775 363 EGEGLVALSQSMKTNLTFSHIYIWGNKFDEATCIAYSDLI 402
Cdd:cd00116  178 GDAGIRALAEGLKANCNLEVLDLNNNGLTDEGASALAETL 217
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
276-363 2.74e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 43.00  E-value: 2.74e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 276 DIKNSGIQQLCDALYLNSSLRYLDVSCNKIThdgmvYLADVLKSNTTLEVIDLSFNRIENaganyLSETLtSHNRSLKAL 355
Cdd:COG4886  165 DLSNNQLTDLPEELGNLTNLKELDLSNNQIT-----DLPEPLGNLTNLEELDLSGNQLTD-----LPEPL-ANLTNLETL 233


                 ....*...
gi 767925775 356 SVVSNNIE 363
Cdd:COG4886  234 DLSNNQLT 241
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
276-390 3.96e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 42.61  E-value: 3.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 276 DIKNSGIQQLCDALYLNSSLRYLDVSCNKITHdgmvyLADVLKSNTTLEVIDLSFNRIENaganyLSETLtSHNRSLKAL 355
Cdd:COG4886  119 DLSGNQLTDLPEELANLTNLKELDLSNNQLTD-----LPEPLGNLTNLKSLDLSNNQLTD-----LPEEL-GNLTNLKEL 187

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 767925775 356 SVVSNNIEgeglvALSQSMK--TNLTfsHIYIWGNKF 390
Cdd:COG4886  188 DLSNNQIT-----DLPEPLGnlTNLE--ELDLSGNQL 217
LRR_8 pfam13855
Leucine rich repeat;
293-362 4.32e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.27  E-value: 4.32e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775  293 SSLRYLDVSCNKITHDGmvylADVLKSNTTLEVIDLSFNRIenagaNYLSETLTSHNRSLKALSVVSNNI 362
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLD----DGAFKGLSNLKVLDLSNNLL-----TTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI smart00368
Leucine rich repeat, ribonuclease inhibitor type;
292-319 4.01e-03

Leucine rich repeat, ribonuclease inhibitor type;


Pssm-ID: 197686 [Multi-domain]  Cd Length: 28  Bit Score: 34.69  E-value: 4.01e-03
                           10        20
                   ....*....|....*....|....*...
gi 767925775   292 NSSLRYLDVSCNKITHDGMVYLADVLKS 319
Cdd:smart00368   1 NPSLRELDLSNNKLGDEGARALAEALKD 28
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
286-392 5.72e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 39.15  E-value: 5.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925775 286 CDALYLNSSLRYLDVSCNKITHdgmvyLADVLKSNTTLEVIDLSFNRIENaganyLSETLtSHNRSLKALSVVSNNIEGe 365
Cdd:COG4886  106 NEELSNLTNLESLDLSGNQLTD-----LPEELANLTNLKELDLSNNQLTD-----LPEPL-GNLTNLKSLDLSNNQLTD- 173

                         90       100
                 ....*....|....*....|....*....
gi 767925775 366 glvaLSQSMK--TNLTfsHIYIWGNKFDE 392
Cdd:COG4886  174 ----LPEELGnlTNLK--ELDLSNNQITD 196
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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