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Conserved domains on  [gi|755562477|ref|XP_011246942|]
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serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X3 [Mus musculus]

Protein Classification

SAPS family protein( domain architecture ID 10517350)

SAPS (SIT4-associating proteins) family protein

Gene Ontology:  GO:0019888|GO:0043666
PubMed:  8649382

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SAPS pfam04499
SIT4 phosphatase-associated protein; This family includes a conserved region from a group of ...
128-513 2.64e-152

SIT4 phosphatase-associated protein; This family includes a conserved region from a group of yeast proteins that associate with the SIT4 phosphatase. This association is required for SIT4's role in G1 cyclin transcription and for bud formation. This family also includes homologous regions from other eukaryotes.


:

Pssm-ID: 398279  Cd Length: 383  Bit Score: 452.46  E-value: 2.64e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  128 LSILISRKPEQIVDFLKKKRDFVDLIIKHIGTSAIMDLLLRLLTCIEPpQPRQDVLNWLNEERIIQRLVEIVHPSQEEDR 207
Cdd:pfam04499   1 NENLLDRKTDQMIEFIRKQENFVDKFLKHIDTPAIMDLLLKLISTDKP-ELPTGVIEWLNEQNLIPKLLDLLSPSYDEDI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  208 HSNASQSLCEIVRLSRDQMLQVQNSTEPDPLLATLEKQEIIEQLLSNIFhKEKNESAIVSAIQILLTLLETRRPTFEGH- 286
Cdd:pfam04499  80 QSNASDFLKAIITISRNAPLQLQSSIGPNELTRELVSEESVEKLLDNML-KGKSGSALVNGVGIIIELIRKNNSDYDPVq 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  287 -----IEICPPGMSHSaCSVNkSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGILDPPVGNTRLNVIRLISSLLQTNTSS 361
Cdd:pfam04499 159 llyttLEEHPPSDRDP-IYLG-HLLRAFSPHLPDFHQLLLDPPKDSPLQTTLGVLIEPLGFERFKIVELIAELLHCSNMS 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  362 INGD---------LMELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPFENAENgtitdqdstgdNLLLKHLFQKCQ 432
Cdd:pfam04499 237 LLNEkkgeklkikLVDLGIIPTILDLFFKYPWNNFLHNVVEDIIQQILNGPMDFSYN-----------SFLVVDLFTDCN 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  433 LIERILEAWDTNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSALVQQLIKDLpdeVRERWETFCTNSLGETNKRNT 512
Cdd:pfam04499 306 LTQRILEGQKESDRFQAEKGPRLGYMGHLTLIAEEVVKFSEKYPPELISPDILEIL---ENEEWEEYVEETLEETRERYN 382

                  .
gi 755562477  513 V 513
Cdd:pfam04499 383 V 383
 
Name Accession Description Interval E-value
SAPS pfam04499
SIT4 phosphatase-associated protein; This family includes a conserved region from a group of ...
128-513 2.64e-152

SIT4 phosphatase-associated protein; This family includes a conserved region from a group of yeast proteins that associate with the SIT4 phosphatase. This association is required for SIT4's role in G1 cyclin transcription and for bud formation. This family also includes homologous regions from other eukaryotes.


Pssm-ID: 398279  Cd Length: 383  Bit Score: 452.46  E-value: 2.64e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  128 LSILISRKPEQIVDFLKKKRDFVDLIIKHIGTSAIMDLLLRLLTCIEPpQPRQDVLNWLNEERIIQRLVEIVHPSQEEDR 207
Cdd:pfam04499   1 NENLLDRKTDQMIEFIRKQENFVDKFLKHIDTPAIMDLLLKLISTDKP-ELPTGVIEWLNEQNLIPKLLDLLSPSYDEDI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  208 HSNASQSLCEIVRLSRDQMLQVQNSTEPDPLLATLEKQEIIEQLLSNIFhKEKNESAIVSAIQILLTLLETRRPTFEGH- 286
Cdd:pfam04499  80 QSNASDFLKAIITISRNAPLQLQSSIGPNELTRELVSEESVEKLLDNML-KGKSGSALVNGVGIIIELIRKNNSDYDPVq 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  287 -----IEICPPGMSHSaCSVNkSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGILDPPVGNTRLNVIRLISSLLQTNTSS 361
Cdd:pfam04499 159 llyttLEEHPPSDRDP-IYLG-HLLRAFSPHLPDFHQLLLDPPKDSPLQTTLGVLIEPLGFERFKIVELIAELLHCSNMS 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  362 INGD---------LMELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPFENAENgtitdqdstgdNLLLKHLFQKCQ 432
Cdd:pfam04499 237 LLNEkkgeklkikLVDLGIIPTILDLFFKYPWNNFLHNVVEDIIQQILNGPMDFSYN-----------SFLVVDLFTDCN 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  433 LIERILEAWDTNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSALVQQLIKDLpdeVRERWETFCTNSLGETNKRNT 512
Cdd:pfam04499 306 LTQRILEGQKESDRFQAEKGPRLGYMGHLTLIAEEVVKFSEKYPPELISPDILEIL---ENEEWEEYVEETLEETRERYN 382

                  .
gi 755562477  513 V 513
Cdd:pfam04499 383 V 383
 
Name Accession Description Interval E-value
SAPS pfam04499
SIT4 phosphatase-associated protein; This family includes a conserved region from a group of ...
128-513 2.64e-152

SIT4 phosphatase-associated protein; This family includes a conserved region from a group of yeast proteins that associate with the SIT4 phosphatase. This association is required for SIT4's role in G1 cyclin transcription and for bud formation. This family also includes homologous regions from other eukaryotes.


Pssm-ID: 398279  Cd Length: 383  Bit Score: 452.46  E-value: 2.64e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  128 LSILISRKPEQIVDFLKKKRDFVDLIIKHIGTSAIMDLLLRLLTCIEPpQPRQDVLNWLNEERIIQRLVEIVHPSQEEDR 207
Cdd:pfam04499   1 NENLLDRKTDQMIEFIRKQENFVDKFLKHIDTPAIMDLLLKLISTDKP-ELPTGVIEWLNEQNLIPKLLDLLSPSYDEDI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  208 HSNASQSLCEIVRLSRDQMLQVQNSTEPDPLLATLEKQEIIEQLLSNIFhKEKNESAIVSAIQILLTLLETRRPTFEGH- 286
Cdd:pfam04499  80 QSNASDFLKAIITISRNAPLQLQSSIGPNELTRELVSEESVEKLLDNML-KGKSGSALVNGVGIIIELIRKNNSDYDPVq 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  287 -----IEICPPGMSHSaCSVNkSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGILDPPVGNTRLNVIRLISSLLQTNTSS 361
Cdd:pfam04499 159 llyttLEEHPPSDRDP-IYLG-HLLRAFSPHLPDFHQLLLDPPKDSPLQTTLGVLIEPLGFERFKIVELIAELLHCSNMS 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  362 INGD---------LMELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPFENAENgtitdqdstgdNLLLKHLFQKCQ 432
Cdd:pfam04499 237 LLNEkkgeklkikLVDLGIIPTILDLFFKYPWNNFLHNVVEDIIQQILNGPMDFSYN-----------SFLVVDLFTDCN 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755562477  433 LIERILEAWDTNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSALVQQLIKDLpdeVRERWETFCTNSLGETNKRNT 512
Cdd:pfam04499 306 LTQRILEGQKESDRFQAEKGPRLGYMGHLTLIAEEVVKFSEKYPPELISPDILEIL---ENEEWEEYVEETLEETRERYN 382

                  .
gi 755562477  513 V 513
Cdd:pfam04499 383 V 383
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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