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Conserved domains on  [gi|755559294|ref|XP_011245003|]
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serine/arginine repetitive matrix protein 2 isoform X3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
cwf21_SRRM2 cd21375
cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive ...
39-102 5.43e-31

cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive matrix protein 2 (SRRM2) is also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803). It is required for pre-mRNA splicing as component of the spliceosome. It contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


:

Pssm-ID: 410601 [Multi-domain]  Cd Length: 64  Bit Score: 117.04  E-value: 5.43e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755559294   39 EEELRHLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21375     1 EEELRRLEAALVKKPNPDILDHERKRRVELKCLELEEMMEEQGYSEEEIQEKVATFRLMLLEKD 64
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
309-686 1.11e-09

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 64.42  E-value: 1.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  309 PSVEPGATNIQQPSSPAPSTKQSSSPyeDKDKKEKSAVRPSPSPERSSTGPELPAPTPLLVEQHVDSPRPLAAIPSSQEP 388
Cdd:PHA03307   75 PGTEAPANESRSTPTWSLSTLAPASP--AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASP 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  389 VNPSSEASPTRGCSPPKSPEKPPQSTSSES--CPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAK 466
Cdd:PHA03307  153 PAAGASPAAVASDAASSRQAALPLSSPEETarAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDA 232
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  467 RDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGwSRSRNTQ 546
Cdd:PHA03307  233 GASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPG-SGPAPSS 311
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  547 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPARRRSRSRTPARRGRSRSRTPARRRSRTRS 626
Cdd:PHA03307  312 PRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRAR 391
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  627 pvrrrsrsrsqarrsgrsrsrtPARRSGRSRSRTPARRGRSRSRTPARRSARSRSRTPAR 686
Cdd:PHA03307  392 ----------------------AAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR 429
PHA03247 super family cl33720
large tegument protein UL36; Provisional
1982-2466 1.89e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.80  E-value: 1.89e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 1982 SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPraargkrsltrsPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2061
Cdd:PHA03247 2596 ARPRAPVDDRGDPRGPAPPSPLPPDTHAPD------------PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR 2663
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2062 sSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSArtpmsvlqqtgGSMMDGPGPRIPDHPRSsvpenhaqsrialalTAIS 2141
Cdd:PHA03247 2664 -PRRARRLGRAAQASSPPQRPRRRAARPTVGSL-----------TSLADPPPPPPTPEPAP---------------HALV 2716
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2142 LGTARPPPSMSAAGLAARMSQVPAPVPLMslrTAPAANLASRIPAASAAAMNLASARTSAIPASvnladsrTPAAAAAMN 2221
Cdd:PHA03247 2717 SATPLPPGPAAARQASPALPAAPAPPAVP---AGPATPGGPARPARPPTTAGPPAPAPPAAPAA-------GPPRRLTRP 2786
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2222 LASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAAlsltgSGTPPTAANYPSSSRTPQAPTPANLVVGprsaHGTA 2301
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA-----GPLPPPTSAQPTAPPPPPGPPPPSLPLG----GSVA 2857
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2302 PVNIAGSRTPAGLAPTNLSSSRMAPALSganLTSPRVPLSAydrvsgRTSPLMLDRARSRTPPSAPSQSRMTSERERAPS 2381
Cdd:PHA03247 2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR---LARPAVSRST------ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2382 PASRM-VQASSQSLLPPAQDRPRSPVPS-AFSDQSRSVVQTTPVAGSQSLSSGTVAKSTSSASDHNGMLSGPAPGIS--- 2456
Cdd:PHA03247 2929 PQPPPpPPPRPQPPLAPTTDPAGAGEPSgAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSswa 3008
                         490
                  ....*....|....*
gi 755559294 2457 -----HAEGGEPPAS 2466
Cdd:PHA03247 3009 sslalHEETDPPPVS 3023
 
Name Accession Description Interval E-value
cwf21_SRRM2 cd21375
cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive ...
39-102 5.43e-31

cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive matrix protein 2 (SRRM2) is also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803). It is required for pre-mRNA splicing as component of the spliceosome. It contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410601 [Multi-domain]  Cd Length: 64  Bit Score: 117.04  E-value: 5.43e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755559294   39 EEELRHLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21375     1 EEELRRLEAALVKKPNPDILDHERKRRVELKCLELEEMMEEQGYSEEEIQEKVATFRLMLLEKD 64
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
309-686 1.11e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 64.42  E-value: 1.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  309 PSVEPGATNIQQPSSPAPSTKQSSSPyeDKDKKEKSAVRPSPSPERSSTGPELPAPTPLLVEQHVDSPRPLAAIPSSQEP 388
Cdd:PHA03307   75 PGTEAPANESRSTPTWSLSTLAPASP--AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASP 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  389 VNPSSEASPTRGCSPPKSPEKPPQSTSSES--CPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAK 466
Cdd:PHA03307  153 PAAGASPAAVASDAASSRQAALPLSSPEETarAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDA 232
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  467 RDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGwSRSRNTQ 546
Cdd:PHA03307  233 GASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPG-SGPAPSS 311
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  547 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPARRRSRSRTPARRGRSRSRTPARRRSRTRS 626
Cdd:PHA03307  312 PRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRAR 391
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  627 pvrrrsrsrsqarrsgrsrsrtPARRSGRSRSRTPARRGRSRSRTPARRSARSRSRTPAR 686
Cdd:PHA03307  392 ----------------------AAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR 429
PHA03247 PHA03247
large tegument protein UL36; Provisional
1982-2466 1.89e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.80  E-value: 1.89e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 1982 SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPraargkrsltrsPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2061
Cdd:PHA03247 2596 ARPRAPVDDRGDPRGPAPPSPLPPDTHAPD------------PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR 2663
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2062 sSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSArtpmsvlqqtgGSMMDGPGPRIPDHPRSsvpenhaqsrialalTAIS 2141
Cdd:PHA03247 2664 -PRRARRLGRAAQASSPPQRPRRRAARPTVGSL-----------TSLADPPPPPPTPEPAP---------------HALV 2716
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2142 LGTARPPPSMSAAGLAARMSQVPAPVPLMslrTAPAANLASRIPAASAAAMNLASARTSAIPASvnladsrTPAAAAAMN 2221
Cdd:PHA03247 2717 SATPLPPGPAAARQASPALPAAPAPPAVP---AGPATPGGPARPARPPTTAGPPAPAPPAAPAA-------GPPRRLTRP 2786
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2222 LASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAAlsltgSGTPPTAANYPSSSRTPQAPTPANLVVGprsaHGTA 2301
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA-----GPLPPPTSAQPTAPPPPPGPPPPSLPLG----GSVA 2857
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2302 PVNIAGSRTPAGLAPTNLSSSRMAPALSganLTSPRVPLSAydrvsgRTSPLMLDRARSRTPPSAPSQSRMTSERERAPS 2381
Cdd:PHA03247 2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR---LARPAVSRST------ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2382 PASRM-VQASSQSLLPPAQDRPRSPVPS-AFSDQSRSVVQTTPVAGSQSLSSGTVAKSTSSASDHNGMLSGPAPGIS--- 2456
Cdd:PHA03247 2929 PQPPPpPPPRPQPPLAPTTDPAGAGEPSgAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSswa 3008
                         490
                  ....*....|....*
gi 755559294 2457 -----HAEGGEPPAS 2466
Cdd:PHA03247 3009 sslalHEETDPPPVS 3023
cwf21 pfam08312
cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a ...
58-101 1.51e-07

cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe. The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevent Prp8 from binding. The structure of this domain has recently been solved which shows this domain to be composed of two alpha helices.


Pssm-ID: 462421 [Multi-domain]  Cd Length: 44  Bit Score: 49.73  E-value: 1.51e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 755559294    58 LDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEK 101
Cdd:pfam08312    1 LEHERKREIEVKVLELRDELEEQGLSEEEIEEKVDELRKKLLAE 44
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
499-603 1.53e-05

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 50.28  E-value: 1.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294   499 KRGHSRSRSPQWRRSRSAQRWgKSRSPQRRGRSRSpqRPGWSRSRNtqrrgrSRSARRGRSHSRSPATRGRSRSRTPARR 578
Cdd:TIGR01642   12 SRGRDRDRSSERPRRRSRDRS-RFRDRHRRSRERS--YREDSRPRD------RRRYDSRSPRSLRYSSVRRSRDRPRRRS 82
                           90       100
                   ....*....|....*....|....*
gi 755559294   579 GRSRSRTPARRRSRSRTPARRRSRS 603
Cdd:TIGR01642   83 RSVRSIEQHRRRLRDRSPSNQWRKD 107
RSRP pfam17069
Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.
436-604 5.73e-04

Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.


Pssm-ID: 293674 [Multi-domain]  Cd Length: 299  Bit Score: 44.77  E-value: 5.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294   436 PESLKPTPAPGSRREISSS-PTSKNRSHGRAKRDKSHSHTPSHRAGRSRS-PATKRGRSRSRTPTKR---GHSRSRSPQW 510
Cdd:pfam17069   10 PGSPQEKKSPSTSSSGSSSrLSSRSRSRSSSRSSRSHSRSSSRFSSRSRSrPRRSRSRSRSRRRHQRkyrRYSRSYSRSR 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294   511 RRSRSAQRWGKSRSPQRRGRSRSPQRpgwSRSRNTQRRGRSRSARRGRSHSRSpatrGRSRSRTPARRGRSRSRTpaRRR 590
Cdd:pfam17069   90 SRSRRRRYYRRSRYRYSRRYYRSPSR---SRSRSRSRSRGRSYYAIWRGSRYY----GFGRTVYPERSPRWRSRS--RTR 160
                          170
                   ....*....|....
gi 755559294   591 SRSRTPARRRSRSR 604
Cdd:pfam17069  161 SRSRTPFRLSEKER 174
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
2199-2422 9.89e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.10  E-value: 9.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  2199 TSAIPASvnlADSRTPAAAAAmnlASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAALSLTGSGTPPTAANYPSS 2278
Cdd:pfam17823  111 ASRALAA---AASSSPSSAAQ---SLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTA 184
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  2279 SRTPQAPTPAnlvvgPRSAHGTAPVNIAGSR-TPAGLAPTNLSSSRMAPALSGANLTSPRVPLSAYDRVSGRTspLMLDR 2357
Cdd:pfam17823  185 ASSTTAASSA-----PTTAASSAPATLTPARgISTAATATGHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAA--LATLA 257
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755559294  2358 ARSRTPPSAPSQSRMTSERERAPSPASRM-VQASSQSLLPPAQDRPRSPVPSAFSDQsrSVVQTTP 2422
Cdd:pfam17823  258 AAAGTVASAAGTINMGDPHARRLSPAKHMpSDTMARNPAAPMGAQAQGPIIQVSTDQ--PVHNTAG 321
 
Name Accession Description Interval E-value
cwf21_SRRM2 cd21375
cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive ...
39-102 5.43e-31

cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive matrix protein 2 (SRRM2) is also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803). It is required for pre-mRNA splicing as component of the spliceosome. It contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410601 [Multi-domain]  Cd Length: 64  Bit Score: 117.04  E-value: 5.43e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755559294   39 EEELRHLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21375     1 EEELRRLEAALVKKPNPDILDHERKRRVELKCLELEEMMEEQGYSEEEIQEKVATFRLMLLEKD 64
cwf21_SRRM3 cd21376
cwf21 domain found in serine/arginine repetitive matrix protein 3 and similar proteins; Serine ...
37-102 2.52e-23

cwf21 domain found in serine/arginine repetitive matrix protein 3 and similar proteins; Serine/arginine repetitive matrix protein 3 (SRRM3) may play a role in regulating breast cancer cell invasiveness. It may also be involved in RYBP-mediated breast cancer progression. SRRM3 contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410602 [Multi-domain]  Cd Length: 68  Bit Score: 95.19  E-value: 2.52e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755559294   37 KGEEELRHLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21376     1 KSEEEIKKLDAALVKKPNREILDHERKRKVELKCMEMQELMEEQGYTEEEIRQKVSTFRQMLMEKE 66
cwf21_SRRM2-like cd21373
cwf21 domain found in serine/arginine repetitive matrix proteins, SRRM2, SRRM3 and similar ...
53-102 6.20e-17

cwf21 domain found in serine/arginine repetitive matrix proteins, SRRM2, SRRM3 and similar proteins; This subfamily includes SRRM2 and SRRM3, both of which contain a cwf21 domain at the N-terminus. SRRM2, also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803), is required for pre-mRNA splicing as component of the spliceosome. SRRM3 may play a role in regulating breast cancer cell invasiveness. It may be involved in RYBP-mediated breast cancer progression. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410600 [Multi-domain]  Cd Length: 50  Bit Score: 76.46  E-value: 6.20e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 755559294   53 PNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21373     1 PNKEILDHERKRKIEVKCLELEDLLEEQGYTEEEIQAKVDEYRALLLEKD 50
cwf21 cd21369
cwf21 domain; The cwf21 domain is involved in mRNA splicing; it binds directly to the ...
55-101 3.02e-10

cwf21 domain; The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevents its binding to Prp8. The domain is composed of two alpha helices. Proteins containing the cwf21 domain include complexed with CEF1 protein 21 (CWC21) from budding yeast, complexed with cdc5 protein 21 (CWF21) from fission yeast, as well as their orthologs, serine/arginine repetitive matrix proteins (SRRM2 and SRRM3) from vertebrates. This domain family also includes U2-associated protein SR140 from Eumetazoa, protein RRC1, and similar proteins from plants.


Pssm-ID: 410596 [Multi-domain]  Cd Length: 48  Bit Score: 57.48  E-value: 3.02e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 755559294   55 PDILDHERKRRVELRCLELEEMMEEQG-YEEQQIQEKVATFRLMLLEK 101
Cdd:cd21369     1 MDEEKRAKKREIELKVMELRDELEEQGrKPEQQIQEKVEHYRDKLLQR 48
cwf21_CWC21-like cd21372
cwf21 domain found in fungal complexed with CEF1 protein 21 (CWC21) and similar proteins; This ...
54-102 4.32e-10

cwf21 domain found in fungal complexed with CEF1 protein 21 (CWC21) and similar proteins; This subfamily includes complexed with CEF1 protein 21 (CWC21) from budding yeast, complexed with cdc5 protein 21 (CWF21) from fission yeast, as well as their orthologs, serine/arginine repetitive matrix proteins (SRRM2 and SRRM3) from vertebrates. Both CWC21 and CWF21 are pre-mRNA-splicing factors that may function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome, together with ISY1. SRRM2 is required for pre-mRNA splicing as a component of the spliceosome. SRRM3 may play a role in regulating breast cancer cell invasiveness. It may be involved in RYBP-mediated breast cancer progression. Members of this family contain a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410599 [Multi-domain]  Cd Length: 49  Bit Score: 57.10  E-value: 4.32e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 755559294   54 NPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21372     1 DKEILEHERKRQIELKCLELRDELEDEGLSEEEIEEKVDELREKLLKEL 49
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
309-686 1.11e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 64.42  E-value: 1.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  309 PSVEPGATNIQQPSSPAPSTKQSSSPyeDKDKKEKSAVRPSPSPERSSTGPELPAPTPLLVEQHVDSPRPLAAIPSSQEP 388
Cdd:PHA03307   75 PGTEAPANESRSTPTWSLSTLAPASP--AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASP 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  389 VNPSSEASPTRGCSPPKSPEKPPQSTSSES--CPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAK 466
Cdd:PHA03307  153 PAAGASPAAVASDAASSRQAALPLSSPEETarAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDA 232
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  467 RDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGwSRSRNTQ 546
Cdd:PHA03307  233 GASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPG-SGPAPSS 311
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  547 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPARRRSRSRTPARRGRSRSRTPARRRSRTRS 626
Cdd:PHA03307  312 PRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRAR 391
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  627 pvrrrsrsrsqarrsgrsrsrtPARRSGRSRSRTPARRGRSRSRTPARRSARSRSRTPAR 686
Cdd:PHA03307  392 ----------------------AAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR 429
PHA03247 PHA03247
large tegument protein UL36; Provisional
1982-2466 1.89e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.80  E-value: 1.89e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 1982 SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPraargkrsltrsPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2061
Cdd:PHA03247 2596 ARPRAPVDDRGDPRGPAPPSPLPPDTHAPD------------PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR 2663
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2062 sSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSArtpmsvlqqtgGSMMDGPGPRIPDHPRSsvpenhaqsrialalTAIS 2141
Cdd:PHA03247 2664 -PRRARRLGRAAQASSPPQRPRRRAARPTVGSL-----------TSLADPPPPPPTPEPAP---------------HALV 2716
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2142 LGTARPPPSMSAAGLAARMSQVPAPVPLMslrTAPAANLASRIPAASAAAMNLASARTSAIPASvnladsrTPAAAAAMN 2221
Cdd:PHA03247 2717 SATPLPPGPAAARQASPALPAAPAPPAVP---AGPATPGGPARPARPPTTAGPPAPAPPAAPAA-------GPPRRLTRP 2786
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2222 LASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAAlsltgSGTPPTAANYPSSSRTPQAPTPANLVVGprsaHGTA 2301
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA-----GPLPPPTSAQPTAPPPPPGPPPPSLPLG----GSVA 2857
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2302 PVNIAGSRTPAGLAPTNLSSSRMAPALSganLTSPRVPLSAydrvsgRTSPLMLDRARSRTPPSAPSQSRMTSERERAPS 2381
Cdd:PHA03247 2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR---LARPAVSRST------ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2382 PASRM-VQASSQSLLPPAQDRPRSPVPS-AFSDQSRSVVQTTPVAGSQSLSSGTVAKSTSSASDHNGMLSGPAPGIS--- 2456
Cdd:PHA03247 2929 PQPPPpPPPRPQPPLAPTTDPAGAGEPSgAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSswa 3008
                         490
                  ....*....|....*
gi 755559294 2457 -----HAEGGEPPAS 2466
Cdd:PHA03247 3009 sslalHEETDPPPVS 3023
cwf21 pfam08312
cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a ...
58-101 1.51e-07

cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe. The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevent Prp8 from binding. The structure of this domain has recently been solved which shows this domain to be composed of two alpha helices.


Pssm-ID: 462421 [Multi-domain]  Cd Length: 44  Bit Score: 49.73  E-value: 1.51e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 755559294    58 LDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEK 101
Cdd:pfam08312    1 LEHERKREIEVKVLELRDELEEQGLSEEEIEEKVDELRKKLLAE 44
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2147-2405 4.17e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 52.54  E-value: 4.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2147 PPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTSAI---PASVNLADSRTPAAAAAMNLA 2223
Cdd:PRK07003  360 PAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAaaaAATRAEAPPAAPAPPATADRG 439
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2224 SPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPTPANLVVGPR-SAHGTAP 2302
Cdd:PRK07003  440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARaPAAASRE 519
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2303 VNIAGSRTPAGLAPTNLSSSRMAPALSGANLTSPRVPLSAYDRVSGRTSPLMLDRARS-----RTPPSAPSQSRMTSERE 2377
Cdd:PRK07003  520 DAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPaaapaAAPKPAAPRVAVQVPTP 599
                         250       260
                  ....*....|....*....|....*...
gi 755559294 2378 RAPSPASRMVQASSQSLLPPAQDRPRSP 2405
Cdd:PRK07003  600 RARAATGDAPPNGAARAEQAAESRGAPP 627
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
499-603 1.53e-05

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 50.28  E-value: 1.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294   499 KRGHSRSRSPQWRRSRSAQRWgKSRSPQRRGRSRSpqRPGWSRSRNtqrrgrSRSARRGRSHSRSPATRGRSRSRTPARR 578
Cdd:TIGR01642   12 SRGRDRDRSSERPRRRSRDRS-RFRDRHRRSRERS--YREDSRPRD------RRRYDSRSPRSLRYSSVRRSRDRPRRRS 82
                           90       100
                   ....*....|....*....|....*
gi 755559294   579 GRSRSRTPARRRSRSRTPARRRSRS 603
Cdd:TIGR01642   83 RSVRSIEQHRRRLRDRSPSNQWRKD 107
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
294-600 1.67e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.55  E-value: 1.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  294 QSPPLASGHQGEGDAPSVEPGATNIQQPSSPAPSTKQSSSPYEDKDKKEKSAVRPSPSPERSSTGPELPAPTPLLVEQHV 373
Cdd:PHA03307  150 ASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAA 229
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  374 DSPRPLAAIPSSQEPvnPSSEASPTRGCSPPKSPEKPPQSTSSESCPP-SPQPTKGSRHASSSPESLKPTPAPGSRREIS 452
Cdd:PHA03307  230 DDAGASSSDSSSSES--SGCGWGPENECPLPRPAPITLPTRIWEASGWnGPSSRPGPASSSSSPRERSPSPSPSSPGSGP 307
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  453 SSPTSKNRSHGRAKRDkSHSHTPSHRAGRSRSPATKRGRSRSRTPtkrghSRSRSPQWRRSrsaqrwgkSRSPQRRGRSR 532
Cdd:PHA03307  308 APSSPRASSSSSSSRE-SSSSSTSSSSESSRGAAVSPGPSPSRSP-----SPSRPPPPADP--------SSPRKRPRPSR 373
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755559294  533 SPQRPGWSRSRNTqrrgrsrsarrGRSHSRSPATRGRSRSRTPAR-RGRSRSRTPARRRSRSRTPARRR 600
Cdd:PHA03307  374 APSSPAASAGRPT-----------RRRARAAVAGRARRRDATGRFpAGRPRPSPLDAGAASGAFYARYP 431
PRK12678 PRK12678
transcription termination factor Rho; Provisional
400-610 5.11e-05

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 48.75  E-value: 5.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  400 GCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAKRDKSHSHTPSHRA 479
Cdd:PRK12678   62 GAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGA 141
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  480 GRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRS 559
Cdd:PRK12678  142 ARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRR 221
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 755559294  560 HSRSPATRGRSRSRTPARRGRSRSRTPARRR-----SRSRTPARRRSRSRTPARRG 610
Cdd:PRK12678  222 DGGDRRGRRRRRDRRDARGDDNREDRGDRDGddgegRGGRRGRRFRDRDRRGRRGG 277
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2200-2425 3.03e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.41  E-value: 3.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2200 SAIPASVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAAL------SLTGSGTPPTAA 2273
Cdd:PRK12323  372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALaaarqaSARGPGGAPAPA 451
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2274 NYPSSSRTPQAPTPANLVVGPRSAHGTAPVNIAGSRTPAGLAPTNLSSSRMAPALSGAnltSPRVPLSAYDRVSGRTSPl 2353
Cdd:PRK12323  452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASP---APAQPDAAPAGWVAESIP- 527
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755559294 2354 mldrarsRTPPSAPSQSRMTSERERAPSPASRMVQASSQSLLPPAQDRPRSPVPSAFSDQSRSVVQTTPVAG 2425
Cdd:PRK12323  528 -------DPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAARLPVRG 592
PRK12678 PRK12678
transcription termination factor Rho; Provisional
379-604 4.73e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 45.67  E-value: 4.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  379 LAAIPSSQEP-VNPSSEASPTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTS 457
Cdd:PRK12678   52 IAAIKEARGGgAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERR 131
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  458 KNRSHGRAKRDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRP 537
Cdd:PRK12678  132 ERGEAARRGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQ 211
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755559294  538 GWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTpARRRSRSRTPARRRSRSR 604
Cdd:PRK12678  212 GDRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRG-GRRGRRFRDRDRRGRRGG 277
RSRP pfam17069
Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.
436-604 5.73e-04

Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.


Pssm-ID: 293674 [Multi-domain]  Cd Length: 299  Bit Score: 44.77  E-value: 5.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294   436 PESLKPTPAPGSRREISSS-PTSKNRSHGRAKRDKSHSHTPSHRAGRSRS-PATKRGRSRSRTPTKR---GHSRSRSPQW 510
Cdd:pfam17069   10 PGSPQEKKSPSTSSSGSSSrLSSRSRSRSSSRSSRSHSRSSSRFSSRSRSrPRRSRSRSRSRRRHQRkyrRYSRSYSRSR 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294   511 RRSRSAQRWGKSRSPQRRGRSRSPQRpgwSRSRNTQRRGRSRSARRGRSHSRSpatrGRSRSRTPARRGRSRSRTpaRRR 590
Cdd:pfam17069   90 SRSRRRRYYRRSRYRYSRRYYRSPSR---SRSRSRSRSRGRSYYAIWRGSRYY----GFGRTVYPERSPRWRSRS--RTR 160
                          170
                   ....*....|....
gi 755559294   591 SRSRTPARRRSRSR 604
Cdd:pfam17069  161 SRSRTPFRLSEKER 174
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2143-2352 6.61e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.25  E-value: 6.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2143 GTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTSAIPASVNLADSRTPAAAAAMNL 2222
Cdd:PRK12323  370 GGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA 449
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2223 ASPRTAVAPSAVN---LADPRTPAASAVNLAGARTPAALAALSltGSGTPP---TAANYPSSSRTPQAPTPANLVVGPRS 2296
Cdd:PRK12323  450 PAPAPAAAPAAAArpaAAGPRPVAAAAAAAPARAAPAAAPAPA--DDDPPPweeLPPEFASPAPAQPDAAPAGWVAESIP 527
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 755559294 2297 AHGTAPvniagsrtPAGLAPTNLSSSRMAPALSGANLTSPRVPLSAYDRVSGRTSP 2352
Cdd:PRK12323  528 DPATAD--------PDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
SF-CC1 TIGR01622
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ...
511-608 1.05e-03

splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.


Pssm-ID: 273721 [Multi-domain]  Cd Length: 494  Bit Score: 44.52  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294   511 RRSRSAQRWGKSRSPQRRGRSRSPQRPGwSRSRNTQRRGRSRSARRgrshsrspatRGRSRSRTPARRGRSRSRTPaRRR 590
Cdd:TIGR01622    2 YRDRERERLRDSSSAGDRDRRRDKGRER-SRDRSRDRERSRSRRRD----------RHRDRDYYRGRERRSRSRRP-NRR 69
                           90
                   ....*....|....*...
gi 755559294   591 SRSRTPARRRSRSRTPAR 608
Cdd:TIGR01622   70 YRPREKRRRRGDSYRRRR 87
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2223-2431 1.32e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.10  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2223 ASPRTAVAPSaVNLADPRTPAASAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPTPANLVVGPRSAHGTAP 2302
Cdd:PRK12323  372 AGPATAAAAP-VAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAP 450
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2303 VNiAGSRTPAGLAPTNLSSSRMAPALSgANLTSPRVPLSAYDRVSGRTSPLM-LDRARSRTPPSAPSQSRMTSERERAPS 2381
Cdd:PRK12323  451 AP-APAAAPAAAARPAAAGPRPVAAAA-AAAPARAAPAAAPAPADDDPPPWEeLPPEFASPAPAQPDAAPAGWVAESIPD 528
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 755559294 2382 PASRMVQASSQSLLPPAqdrPRSPVPSAFSDQSRSVVQTTPVAGSQSLSS 2431
Cdd:PRK12323  529 PATADPDDAFETLAPAP---AAAPAPRAAAATEPVVAPRPPRASASGLPD 575
PHA03247 PHA03247
large tegument protein UL36; Provisional
165-462 1.47e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  165 PEPPKPYSLVRETSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKK 244
Cdd:PHA03247 2702 PPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPR 2781
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKI------HTTALTGQSPPLASGHQGEGDAP--SVEPGAT 316
Cdd:PHA03247 2782 RLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASpagplpPPTSAQPTAPPPPPGPPPPSLPLggSVAPGGD 2861
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  317 NIQQPSSPAPSTKQSSSPYEDKDKKEKSAVRPSPSPERSSTGPELPAPTPllveqhvDSPRPLAAIPSSQEPVNPSSeAS 396
Cdd:PHA03247 2862 VRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQP-------QAPPPPQPQPQPPPPPQPQP-PP 2933
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755559294  397 PTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSH 462
Cdd:PHA03247 2934 PPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGH 2999
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2104-2402 1.71e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 44.07  E-value: 1.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2104 TGGSmmdGPGPRIPDHPRSSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASR 2183
Cdd:PRK07003  363 TGGG---APGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRG 439
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2184 IPAASAAAMNLASARTSAIPASVNLADSRTPAAAAAMNlASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAALSL 2263
Cdd:PRK07003  440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSA-SAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASR 518
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2264 TGSGTPPTAANYPSSSRTPQAPTPANlvvgpRSAHGTAPVNI---AGSRTPAGlaptnlsSSRMAPALSGANLTSPRVPL 2340
Cdd:PRK07003  519 EDAPAAAAPPAPEARPPTPAAAAPAA-----RAGGAAAALDVlrnAGMRVSSD-------RGARAAAAAKPAAAPAAAPK 586
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755559294 2341 SAYDRVSgrtSPLMLDRARSRTPPSAPSQSrmtsererAPSPASrmvqASSQSLLPPAQDRP 2402
Cdd:PRK07003  587 PAAPRVA---VQVPTPRARAATGDAPPNGA--------ARAEQA----AESRGAPPPWEDIP 633
PHA03247 PHA03247
large tegument protein UL36; Provisional
162-610 2.00e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 2.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  162 QIAPEPPKPYSLVRETsssRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSK 241
Cdd:PHA03247 2572 RPAPRPSEPAVTSRAR---RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPP 2648
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  242 DKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKIHTTALTGQSPPlasghqgeGDAPSVEPGATNIQQP 321
Cdd:PHA03247 2649 PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP--------PPTPEPAPHALVSATP 2720
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  322 SSPAPSTKQSSSPyedkdkkeksAVRPSPSPERSSTGPELPAPtpllvEQHVDSPRPLAAIPSSQEPVNPSSEASPTrgc 401
Cdd:PHA03247 2721 LPPGPAAARQASP----------ALPAAPAPPAVPAGPATPGG-----PARPARPPTTAGPPAPAPPAAPAAGPPRR--- 2782
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  402 SPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAKRDKSHSHT-----PS 476
Cdd:PHA03247 2783 LTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSvapggDV 2862
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  477 HRAGRSRSPATK---RGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRS 553
Cdd:PHA03247 2863 RRRPPSRSPAAKpaaPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP 2942
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 755559294  554 ARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPaRRRSRSRTPARRRSRSRTPARRG 610
Cdd:PHA03247 2943 LAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVP-RFRVPQPAPSREAPASSTPPLTG 2998
PHA03247 PHA03247
large tegument protein UL36; Provisional
2164-2613 2.12e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 2.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2164 PAPVPLMSLRTAPAANLAsriPAASAAAMNLASARTSAIPASvnlADSRTPAAAAAMNLASPRTAVAPSAVNLADP--RT 2241
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPA---PRPSEPAVTSRARRPDAPPQS---ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPppPS 2630
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2242 PAASAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPTPANLVVGPRSAHGTAPVNIAGS--------RTPAG 2313
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSladpppppPTPEP 2710
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2314 LAPTNLSSSRMAPALSGANLTSPRVPLSAYDRVSGRTSPLMLDRARSRTPPSAPSQSRMTSERERAPSPASRMVQASSQS 2393
Cdd:PHA03247 2711 APHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVAS 2790
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2394 LlppAQDRPRSPVPSAFSDQSRSVVQTTPVAGSQSLSSGTVAKSTSSASDHNGMLSGPAPGISHAEGGEPPASTGAQQ-P 2472
Cdd:PHA03247 2791 L---SESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRpP 2867
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2473 STLAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSslPAQPEVALKRVPSPTPVPKEAIREGRPQEP 2552
Cdd:PHA03247 2868 SRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPP--PPQPQPQPPPPPQPQPPPPPPPRPQPPLAP 2945
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755559294 2553 TP------------------AKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQAL 2613
Cdd:PHA03247 2946 TTdpagagepsgavpqpwlgALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPPVSL 3024
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
313-444 3.31e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 42.84  E-value: 3.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  313 PGATNIQQPSSPAPStkQSSSPYEdkdkkEKSAVRPSPSPERSSTGPELPAPTPllVEQHVDSPRPLAAIPSSQEPVNPS 392
Cdd:PRK14971  370 SGGRGPKQHIKPVFT--QPAAAPQ-----PSAAAAASPSPSQSSAAAQPSAPQS--ATQPAGTPPTVSVDPPAAVPVNPP 440
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 755559294  393 SEASPTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPA 444
Cdd:PRK14971  441 STAPQAVRPAQFKEEKKIPVSKVSSLGPSTLRPIQEKAEQATGNIKEAPTGT 492
PRK12678 PRK12678
transcription termination factor Rho; Provisional
359-590 3.47e-03

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 42.97  E-value: 3.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  359 PELPAPTPLLVEQHVDSPRPLAAIPSSQEPVNPSSEASPTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPES 438
Cdd:PRK12678   68 ATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGAARKAGE 147
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  439 LKPTPAPGSRREISSSPTSKNRSHGRAKRDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQR 518
Cdd:PRK12678  148 GGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRR 227
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755559294  519 WGKSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARrgrshsrspatRGRSRSRTPARRGRSRSRTPARRR 590
Cdd:PRK12678  228 GRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGRRGR-----------RFRDRDRRGRRGGDGGNEREPELR 288
PHA03247 PHA03247
large tegument protein UL36; Provisional
2043-2619 4.23e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 4.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2043 ATPPATRNHS--GSRTPPVALSSSRMSCFSRPSMSPTPlDRCRSPGmlEPLGSARTPMsvlqQTGGSMMDGPGPRIPDHP 2120
Cdd:PHA03247 2558 AAPPAAPDRSvpPPRPAPRPSEPAVTSRARRPDAPPQS-ARPRAPV--DDRGDPRGPA----PPSPLPPDTHAPDPPPPS 2630
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2121 RSSVPENHAQSRIALA------LTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLR--TAPAANLAsRIPAASAAAM 2192
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVppperpRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARptVGSLTSLA-DPPPPPPTPE 2709
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2193 NLASARTSAIPASVNLADSRTPAAAAAMNLASPRTAVAPSAVnlADPRTPAASAVNlAGARTPAALAALSLTGSGTPPTA 2272
Cdd:PHA03247 2710 PAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATP--GGPARPARPPTT-AGPPAPAPPAAPAAGPPRRLTRP 2786
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2273 ANYPSSSRTPQAPTPANLVVGPRSAHGTAPVnIAGSRTPAGLAPTNLSSSRMAPALsganltsPRVPLSAYDRVSGRTSP 2352
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAA-LPPAASPAGPLPPPTSAQPTAPPP-------PPGPPPPSLPLGGSVAP 2858
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2353 --LMLDRARSRTPPSAPSQSRMTSERERAPSPASRmvQASSQSLLPPAQDRPRSPVPSAfsdqsrsvvQTTPVAGSQSLS 2430
Cdd:PHA03247 2859 ggDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSR--STESFALPPDQPERPPQPQAPP---------PPQPQPQPPPPP 2927
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2431 SGTVAKSTSSASDhngmlSGPAPGISHAEGGEPpasTGAQQPSTLAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS 2510
Cdd:PHA03247 2928 QPQPPPPPPPRPQ-----PPLAPTTDPAGAGEP---SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGH 2999
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2511 GSSSSDSEGSSLPAQPEVAlkrvpsptpvpkeairegrpqePTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2590
Cdd:PHA03247 3000 SLSRVSSWASSLALHEETD----------------------PPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEALDP 3057
                         570       580
                  ....*....|....*....|....*....
gi 755559294 2591 SSSSSSSSSSSSPSPAKPGPQALPKPASP 2619
Cdd:PHA03247 3058 LPPEPHDPFAHEPDPATPEAGARESPSSQ 3086
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
309-462 6.15e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.21  E-value: 6.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294   309 PSVEPGATNIQQPSSPAP--STKQSSSPYEDKDKKEKSAVRPSPSPERSST---GPELPAPTPLLV--EQHVDSPRPLAA 381
Cdd:pfam05109  449 PSSTHVPTNLTAPASTGPtvSTADVTSPTPAGTTSGASPVTPSPSPRDNGTeskAPDMTSPTSAVTtpTPNATSPTPAVT 528
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294   382 IPSSQEPVNPSSEASPTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESlkPTPAPGSRREISSSPTSKNRS 461
Cdd:pfam05109  529 TPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTT--PTPNATSPTVGETSPQANTTN 606

                   .
gi 755559294   462 H 462
Cdd:pfam05109  607 H 607
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
350-726 7.10e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.08  E-value: 7.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  350 PSPERSSTGPELPAPTPLLVEQHVDSPRPLAAIPSSQEPVNPSSEASPTRGCSPPKSPEKPPQSTSSEScpPSPQPTKGS 429
Cdd:PHA03307   39 SQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPT--PPGPSSPDP 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  430 RHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAKR-DKSHSHTPSHRAG-RSRSPATKRGRSRSRTPTKRGHSR--S 505
Cdd:PHA03307  117 PPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAaGASPAAVASDAASsRQAALPLSSPEETARAPSSPPAEPppS 196
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  506 RSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRT 585
Cdd:PHA03307  197 TPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWN 276
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  586 PARRR---SRSRTPARRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSQARRSGRSRSRTPArrsgrsrsrtpa 662
Cdd:PHA03307  277 GPSSRpgpASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPG------------ 344
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755559294  663 rRGRSRSRTPARRSARSRSRTPARRGRSRSRTPARRRSRSRSLVRRGRShSRTPQRRGRSGSSS 726
Cdd:PHA03307  345 -PSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA-AVAGRARRRDATGR 406
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
525-608 7.21e-03

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 41.80  E-value: 7.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294   525 PQRRGRSRSPQRP-GWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPA-----RRGRSRSRTPARRRSRSR-TPA 597
Cdd:TIGR01642   12 SRGRDRDRSSERPrRRSRDRSRFRDRHRRSRERSYREDSRPRDRRRYDSRSPRslrysSVRRSRDRPRRRSRSVRSiEQH 91
                           90
                   ....*....|.
gi 755559294   598 RRRSRSRTPAR 608
Cdd:TIGR01642   92 RRRLRDRSPSN 102
PHA03247 PHA03247
large tegument protein UL36; Provisional
2230-2610 7.67e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 7.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2230 APSAVNLADPRTPAASAVNLAGARTPAALAAlslTGSGTPPTAANYPSSSRTPQAPtpanlvvgPRSAHGTAPVNIAGSR 2309
Cdd:PHA03247 2552 PPPLPPAAPPAAPDRSVPPPRPAPRPSEPAV---TSRARRPDAPPQSARPRAPVDD--------RGDPRGPAPPSPLPPD 2620
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2310 TPAGLAPTNLSSSRMAPALSGANLTSPRVPLSAYDRVSGRTSPLMLDRARSRTP-PSAPSQSrmtsERERAPSPASRMVQ 2388
Cdd:PHA03247 2621 THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAqASSPPQR----PRRRAARPTVGSLT 2696
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2389 ASSQsllPPAQDRPRSPVPSAFSdqSRSVVQTTPVAGSQSLSSGTVAKSTSSASDHNGMLSGPAPGISHAEGGEPPASTG 2468
Cdd:PHA03247 2697 SLAD---PPPPPPTPEPAPHALV--SATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAP 2771
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294 2469 AQQPST---LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPAQPEVALKRVPSPTPVPKEAIR 2545
Cdd:PHA03247 2772 PAAPAAgppRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP 2851
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755559294 2546 EGRPQEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2610
Cdd:PHA03247 2852 LGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPP 2916
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
2199-2422 9.89e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.10  E-value: 9.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  2199 TSAIPASvnlADSRTPAAAAAmnlASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAALSLTGSGTPPTAANYPSS 2278
Cdd:pfam17823  111 ASRALAA---AASSSPSSAAQ---SLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTA 184
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755559294  2279 SRTPQAPTPAnlvvgPRSAHGTAPVNIAGSR-TPAGLAPTNLSSSRMAPALSGANLTSPRVPLSAYDRVSGRTspLMLDR 2357
Cdd:pfam17823  185 ASSTTAASSA-----PTTAASSAPATLTPARgISTAATATGHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAA--LATLA 257
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755559294  2358 ARSRTPPSAPSQSRMTSERERAPSPASRM-VQASSQSLLPPAQDRPRSPVPSAFSDQsrSVVQTTP 2422
Cdd:pfam17823  258 AAAGTVASAAGTINMGDPHARRLSPAKHMpSDTMARNPAAPMGAQAQGPIIQVSTDQ--PVHNTAG 321
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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