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Conserved domains on  [gi|755511569|ref|XP_011239048|]
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uncharacterized protein KIAA0232 isoform X1 [Mus musculus]

Protein Classification

DUF4603 domain-containing protein( domain architecture ID 10634086)

DUF4603 domain-containing protein similar to Homo sapiens protein KIAA0232

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 23-1330 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


:

Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2172.26  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569    23 GPVSVSDMSLLHALGPVQTWLGQELEKCGIDAMIYSRYILSLLLHDSYDYDLQEQENDI-LSWEKGAYKKWGRSKKKCSD 101
Cdd:pfam15376    1 GPLPASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIfLGWEKGAGKKWGKSKKKGTD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   102 LTLEEMKKQAAVQCLRSASDESSGIETLVEELCCRLKDLQSEQ--EEKIHKKLEGSPSPEEELSPTAKDQVEMYvrllsl 179
Cdd:pfam15376   81 LSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQkeEKKINKKSEGSQSPERDESPSSKDQVEMY------ 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   180 kyYEAFPPLSEKPVCLQEIMTVWNKSKPCSYSSSSSSsTVPPASTDTSSPKDCNSESEAVRERSSVASVPMHEKA-QSRS 258
Cdd:pfam15376  155 --YEAFPPLSEKPVCLQEIMTVWNKAKACSYSSSSSS-AAPQTSTDTSSPKDCNSEGEATKERNSEAPATTSERTqQRRS 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   259 RHEKESKLSSSTIEEKPAFY-KRQIRHKPEGKTRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKARE-IRNRKGRN 336
Cdd:pfam15376  232 KKEKENRFHNGAAEEKSAVHsKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSREaVRNKKGRN 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   337 GQNRHSLKHCGKAERGVHAGSGGSSSSSSNGsiRQLCKRGKRPAKETgRSDSGNTAVKDLYVDSRNNKEYKEEPLWYTEP 416
Cdd:pfam15376  312 GQVKLALKVIDKEERRNAGGSSSSASGGSIK--QQLCKKGKRPLKEI-RKDPGWVEGKESGGEARNKKEYMEEPLWYTEP 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   417 IAEYFVPLSRKSKLETTYRNREDTSTLTA--EAVEDLSDSVRGLCISNSNIHRTYLAAGTFIDGHFVEMPAVINEDIDLA 494
Cdd:pfam15376  389 ITEYFVPLSRKSKLETKYRSKEDSPDGFAlsIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNEAADLN 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   495 GTSLCSLPEDNKYLDDIHLSELTHFYEVDIDQSMLDPGASETMQgESRILNMIRQKSKENTDFEAECCIVLDGMELQGER 574
Cdd:pfam15376  469 GTSSCPQPEDNKDLDDEHLSEFTHFYEVDIYQSILDPSASDSVQ-ESRILNMIRQKSKEQRDFEAECCIVLDGLELQGES 547

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   575 AIWTDSTSSVGAEGFFLQDLGNLAQFWECCS-SSSGDADGESFGGDSPVRLSPILDSTMLSSHILAGNQE-PFSNINEGS 652
Cdd:pfam15376  548 AIRADSTSASGAEGFLMQDLENIAQVWECCSsSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEeLFSEANEGS 627

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   653 GIN-SCFSVFEVQCSNSVLPFSFETLNLGSEHADSS--ANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEE 729
Cdd:pfam15376  628 GLNsSCFSLFEVQYDSSTFPFPRDSLTLGHENTDSSscLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSEE 707

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   730 ARSDNETLNIQFEESTQFTAEDINYVVPRVSSDFVDEELLDFLQDETCQQNSRTLGEIPTLVFKKRSKLESVCGIQLEQK 809
Cdd:pfam15376  708 TRSDNEQFNAQAEESAQFGNEEINCVIPPLSSTYLEEELLDFLQEESCHQEEVSVSTASNQTFKKKSKLESVCGIALEQD 787

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   810 aESKNFETTH-ACSESSPHGDGYSSGVIKDIWTKMVGRSSVAAVETERTGEELFSTDVNNY-CCCLDTEAKMEALQEPSR 887
Cdd:pfam15376  788 -ESKQYESTGvFSDNSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYcCCCLDVEAKGEPLQEQKK 866

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   888 AVQRSEYHLWEGQKENMEKRAFVSSELSKVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPGHTKG 967
Cdd:pfam15376  867 AVQRSEYHLWEGQKENLEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSDSRG 946

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   968 SLLQCAASDVVTIAGTDVFMTPGNSFAPGHRQLWKPFVSFEQSDMP-KSGENGVNKGFSFIFHEDLLGACSNFQVEDPGL 1046
Cdd:pfam15376  947 SLLQCAASDVVTIAGTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAiKGGGDGLNKGFSFIFHEDLLGSCGNFRGEEPGL 1026

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569  1047 EYSLSSFDLSNPFSQVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVERTQYRAIRISPRTHFRPISASE 1126
Cdd:pfam15376 1027 EYPFSSFDLNNPFSQVLHVECSFEPEDIASFSPGFKPKSILCSDSENEVFHPRIYGINRTQYRAIRISPRTHFRPISASE 1106

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569  1127 LSPGGGSESEFESEKDEASVPIPSQVDVFEDPQADLKPLEEDAEKEGHYYGKLELESGKFLPRLKKSGMEKSAQTSLDSQ 1206
Cdd:pfam15376 1107 LSPGGGSESEAESEKEEASIPVLSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQ 1186

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569  1207 EEATGILP--KQNQCLECNFNESLE-INLESSAANCKIMTQCEEE---MSEFCSCKAGCQFPACEDNPVSSGQLEEigkk 1280
Cdd:pfam15376 1187 EGSGGLLPiaEQEICLDCSIAASLEsISTEGSKTNCKIGEPQKEEssgEKEFCSCKAACQIPKYGKAYDFAGDLPE---- 1262

                         1290      1300      1310      1320      1330
                   ....*....|....*....|....*....|....*....|....*....|
gi 755511569  1281 eneerskilptttiflrflFPVLNTDVQEVTRNQEKQSWWEKALYSPLFP 1330
Cdd:pfam15376 1263 -------------------FPLLNIDLQGGTGSQQEECWWQKALCSPLFP 1293
 
Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 23-1330 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2172.26  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569    23 GPVSVSDMSLLHALGPVQTWLGQELEKCGIDAMIYSRYILSLLLHDSYDYDLQEQENDI-LSWEKGAYKKWGRSKKKCSD 101
Cdd:pfam15376    1 GPLPASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIfLGWEKGAGKKWGKSKKKGTD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   102 LTLEEMKKQAAVQCLRSASDESSGIETLVEELCCRLKDLQSEQ--EEKIHKKLEGSPSPEEELSPTAKDQVEMYvrllsl 179
Cdd:pfam15376   81 LSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQkeEKKINKKSEGSQSPERDESPSSKDQVEMY------ 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   180 kyYEAFPPLSEKPVCLQEIMTVWNKSKPCSYSSSSSSsTVPPASTDTSSPKDCNSESEAVRERSSVASVPMHEKA-QSRS 258
Cdd:pfam15376  155 --YEAFPPLSEKPVCLQEIMTVWNKAKACSYSSSSSS-AAPQTSTDTSSPKDCNSEGEATKERNSEAPATTSERTqQRRS 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   259 RHEKESKLSSSTIEEKPAFY-KRQIRHKPEGKTRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKARE-IRNRKGRN 336
Cdd:pfam15376  232 KKEKENRFHNGAAEEKSAVHsKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSREaVRNKKGRN 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   337 GQNRHSLKHCGKAERGVHAGSGGSSSSSSNGsiRQLCKRGKRPAKETgRSDSGNTAVKDLYVDSRNNKEYKEEPLWYTEP 416
Cdd:pfam15376  312 GQVKLALKVIDKEERRNAGGSSSSASGGSIK--QQLCKKGKRPLKEI-RKDPGWVEGKESGGEARNKKEYMEEPLWYTEP 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   417 IAEYFVPLSRKSKLETTYRNREDTSTLTA--EAVEDLSDSVRGLCISNSNIHRTYLAAGTFIDGHFVEMPAVINEDIDLA 494
Cdd:pfam15376  389 ITEYFVPLSRKSKLETKYRSKEDSPDGFAlsIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNEAADLN 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   495 GTSLCSLPEDNKYLDDIHLSELTHFYEVDIDQSMLDPGASETMQgESRILNMIRQKSKENTDFEAECCIVLDGMELQGER 574
Cdd:pfam15376  469 GTSSCPQPEDNKDLDDEHLSEFTHFYEVDIYQSILDPSASDSVQ-ESRILNMIRQKSKEQRDFEAECCIVLDGLELQGES 547

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   575 AIWTDSTSSVGAEGFFLQDLGNLAQFWECCS-SSSGDADGESFGGDSPVRLSPILDSTMLSSHILAGNQE-PFSNINEGS 652
Cdd:pfam15376  548 AIRADSTSASGAEGFLMQDLENIAQVWECCSsSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEeLFSEANEGS 627

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   653 GIN-SCFSVFEVQCSNSVLPFSFETLNLGSEHADSS--ANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEE 729
Cdd:pfam15376  628 GLNsSCFSLFEVQYDSSTFPFPRDSLTLGHENTDSSscLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSEE 707

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   730 ARSDNETLNIQFEESTQFTAEDINYVVPRVSSDFVDEELLDFLQDETCQQNSRTLGEIPTLVFKKRSKLESVCGIQLEQK 809
Cdd:pfam15376  708 TRSDNEQFNAQAEESAQFGNEEINCVIPPLSSTYLEEELLDFLQEESCHQEEVSVSTASNQTFKKKSKLESVCGIALEQD 787

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   810 aESKNFETTH-ACSESSPHGDGYSSGVIKDIWTKMVGRSSVAAVETERTGEELFSTDVNNY-CCCLDTEAKMEALQEPSR 887
Cdd:pfam15376  788 -ESKQYESTGvFSDNSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYcCCCLDVEAKGEPLQEQKK 866

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   888 AVQRSEYHLWEGQKENMEKRAFVSSELSKVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPGHTKG 967
Cdd:pfam15376  867 AVQRSEYHLWEGQKENLEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSDSRG 946

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   968 SLLQCAASDVVTIAGTDVFMTPGNSFAPGHRQLWKPFVSFEQSDMP-KSGENGVNKGFSFIFHEDLLGACSNFQVEDPGL 1046
Cdd:pfam15376  947 SLLQCAASDVVTIAGTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAiKGGGDGLNKGFSFIFHEDLLGSCGNFRGEEPGL 1026

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569  1047 EYSLSSFDLSNPFSQVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVERTQYRAIRISPRTHFRPISASE 1126
Cdd:pfam15376 1027 EYPFSSFDLNNPFSQVLHVECSFEPEDIASFSPGFKPKSILCSDSENEVFHPRIYGINRTQYRAIRISPRTHFRPISASE 1106

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569  1127 LSPGGGSESEFESEKDEASVPIPSQVDVFEDPQADLKPLEEDAEKEGHYYGKLELESGKFLPRLKKSGMEKSAQTSLDSQ 1206
Cdd:pfam15376 1107 LSPGGGSESEAESEKEEASIPVLSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQ 1186

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569  1207 EEATGILP--KQNQCLECNFNESLE-INLESSAANCKIMTQCEEE---MSEFCSCKAGCQFPACEDNPVSSGQLEEigkk 1280
Cdd:pfam15376 1187 EGSGGLLPiaEQEICLDCSIAASLEsISTEGSKTNCKIGEPQKEEssgEKEFCSCKAACQIPKYGKAYDFAGDLPE---- 1262

                         1290      1300      1310      1320      1330
                   ....*....|....*....|....*....|....*....|....*....|
gi 755511569  1281 eneerskilptttiflrflFPVLNTDVQEVTRNQEKQSWWEKALYSPLFP 1330
Cdd:pfam15376 1263 -------------------FPLLNIDLQGGTGSQQEECWWQKALCSPLFP 1293
 
Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 23-1330 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2172.26  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569    23 GPVSVSDMSLLHALGPVQTWLGQELEKCGIDAMIYSRYILSLLLHDSYDYDLQEQENDI-LSWEKGAYKKWGRSKKKCSD 101
Cdd:pfam15376    1 GPLPASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIfLGWEKGAGKKWGKSKKKGTD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   102 LTLEEMKKQAAVQCLRSASDESSGIETLVEELCCRLKDLQSEQ--EEKIHKKLEGSPSPEEELSPTAKDQVEMYvrllsl 179
Cdd:pfam15376   81 LSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQkeEKKINKKSEGSQSPERDESPSSKDQVEMY------ 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   180 kyYEAFPPLSEKPVCLQEIMTVWNKSKPCSYSSSSSSsTVPPASTDTSSPKDCNSESEAVRERSSVASVPMHEKA-QSRS 258
Cdd:pfam15376  155 --YEAFPPLSEKPVCLQEIMTVWNKAKACSYSSSSSS-AAPQTSTDTSSPKDCNSEGEATKERNSEAPATTSERTqQRRS 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   259 RHEKESKLSSSTIEEKPAFY-KRQIRHKPEGKTRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKARE-IRNRKGRN 336
Cdd:pfam15376  232 KKEKENRFHNGAAEEKSAVHsKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSREaVRNKKGRN 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   337 GQNRHSLKHCGKAERGVHAGSGGSSSSSSNGsiRQLCKRGKRPAKETgRSDSGNTAVKDLYVDSRNNKEYKEEPLWYTEP 416
Cdd:pfam15376  312 GQVKLALKVIDKEERRNAGGSSSSASGGSIK--QQLCKKGKRPLKEI-RKDPGWVEGKESGGEARNKKEYMEEPLWYTEP 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   417 IAEYFVPLSRKSKLETTYRNREDTSTLTA--EAVEDLSDSVRGLCISNSNIHRTYLAAGTFIDGHFVEMPAVINEDIDLA 494
Cdd:pfam15376  389 ITEYFVPLSRKSKLETKYRSKEDSPDGFAlsIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNEAADLN 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   495 GTSLCSLPEDNKYLDDIHLSELTHFYEVDIDQSMLDPGASETMQgESRILNMIRQKSKENTDFEAECCIVLDGMELQGER 574
Cdd:pfam15376  469 GTSSCPQPEDNKDLDDEHLSEFTHFYEVDIYQSILDPSASDSVQ-ESRILNMIRQKSKEQRDFEAECCIVLDGLELQGES 547

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   575 AIWTDSTSSVGAEGFFLQDLGNLAQFWECCS-SSSGDADGESFGGDSPVRLSPILDSTMLSSHILAGNQE-PFSNINEGS 652
Cdd:pfam15376  548 AIRADSTSASGAEGFLMQDLENIAQVWECCSsSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEeLFSEANEGS 627

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   653 GIN-SCFSVFEVQCSNSVLPFSFETLNLGSEHADSS--ANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEE 729
Cdd:pfam15376  628 GLNsSCFSLFEVQYDSSTFPFPRDSLTLGHENTDSSscLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSEE 707

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   730 ARSDNETLNIQFEESTQFTAEDINYVVPRVSSDFVDEELLDFLQDETCQQNSRTLGEIPTLVFKKRSKLESVCGIQLEQK 809
Cdd:pfam15376  708 TRSDNEQFNAQAEESAQFGNEEINCVIPPLSSTYLEEELLDFLQEESCHQEEVSVSTASNQTFKKKSKLESVCGIALEQD 787

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   810 aESKNFETTH-ACSESSPHGDGYSSGVIKDIWTKMVGRSSVAAVETERTGEELFSTDVNNY-CCCLDTEAKMEALQEPSR 887
Cdd:pfam15376  788 -ESKQYESTGvFSDNSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYcCCCLDVEAKGEPLQEQKK 866

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   888 AVQRSEYHLWEGQKENMEKRAFVSSELSKVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPGHTKG 967
Cdd:pfam15376  867 AVQRSEYHLWEGQKENLEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSDSRG 946

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569   968 SLLQCAASDVVTIAGTDVFMTPGNSFAPGHRQLWKPFVSFEQSDMP-KSGENGVNKGFSFIFHEDLLGACSNFQVEDPGL 1046
Cdd:pfam15376  947 SLLQCAASDVVTIAGTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAiKGGGDGLNKGFSFIFHEDLLGSCGNFRGEEPGL 1026

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569  1047 EYSLSSFDLSNPFSQVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVERTQYRAIRISPRTHFRPISASE 1126
Cdd:pfam15376 1027 EYPFSSFDLNNPFSQVLHVECSFEPEDIASFSPGFKPKSILCSDSENEVFHPRIYGINRTQYRAIRISPRTHFRPISASE 1106

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569  1127 LSPGGGSESEFESEKDEASVPIPSQVDVFEDPQADLKPLEEDAEKEGHYYGKLELESGKFLPRLKKSGMEKSAQTSLDSQ 1206
Cdd:pfam15376 1107 LSPGGGSESEAESEKEEASIPVLSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQ 1186

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755511569  1207 EEATGILP--KQNQCLECNFNESLE-INLESSAANCKIMTQCEEE---MSEFCSCKAGCQFPACEDNPVSSGQLEEigkk 1280
Cdd:pfam15376 1187 EGSGGLLPiaEQEICLDCSIAASLEsISTEGSKTNCKIGEPQKEEssgEKEFCSCKAACQIPKYGKAYDFAGDLPE---- 1262

                         1290      1300      1310      1320      1330
                   ....*....|....*....|....*....|....*....|....*....|
gi 755511569  1281 eneerskilptttiflrflFPVLNTDVQEVTRNQEKQSWWEKALYSPLFP 1330
Cdd:pfam15376 1263 -------------------FPLLNIDLQGGTGSQQEECWWQKALCSPLFP 1293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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