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Conserved domains on  [gi|741927987|ref|XP_010803885|]
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peroxisomal biogenesis factor 5 isoform X3 [Bos taurus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 1000094)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 333-550 2.91e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 91.98  E-value: 2.91e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 333 MEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVAPGEEGAG 412
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 413 GVGLGSSKRILGsllsdsLFLEVKELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKL 492
Cdd:COG3914   81 LELAALLLQALG------RYEEALALYRRALALNPDN--AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNL 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 741927987 493 GATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 550
Cdd:COG3914  153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 250-398 1.24e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


:

Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 1.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 250 DFWDKLQAELEEMAKRDAEAHPWLSDHDDLTSASYDKGYHFEEENPLRDHPQPFEEGLRRLqeGDLPNAVLLFEAAVQQD 329
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKL--GDFEESLALLEQALQLD 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 741927987 330 PKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYTP 398
Cdd:COG5010   85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 333-550 2.91e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 91.98  E-value: 2.91e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 333 MEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVAPGEEGAG 412
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 413 GVGLGSSKRILGsllsdsLFLEVKELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKL 492
Cdd:COG3914   81 LELAALLLQALG------RYEEALALYRRALALNPDN--AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNL 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 741927987 493 GATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 550
Cdd:COG3914  153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 310-547 3.34e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 72.81  E-value: 3.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  310 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFtneSLQRQACET 389
Cdd:TIGR02917  33 LQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAY---LLQGKFQQV 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  390 LRdwlrYTPAYAHLvaPGEEGAGGVGLgsskRILGSLLSDSLfLEVKELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYD 469
Cdd:TIGR02917 110 LD----ELPGKTLL--DDEGAAELLAL----RGLAYLGLGQL-ELAQKSYEQALAIDPRS--LYAKLGLAQLALAENRFD 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 741927987  470 KAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHfLEAL 547
Cdd:TIGR02917 177 EARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKH-ADAL 253
TPR_12 pfam13424
Tetratricopeptide repeat;
488-552 4.00e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.07  E-value: 4.00e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 741927987  488 LWNKLGATLANGNQSEEAVAAYRRALELQ--------PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRK 552
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 250-398 1.24e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 1.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 250 DFWDKLQAELEEMAKRDAEAHPWLSDHDDLTSASYDKGYHFEEENPLRDHPQPFEEGLRRLqeGDLPNAVLLFEAAVQQD 329
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKL--GDFEESLALLEQALQLD 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 741927987 330 PKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYTP 398
Cdd:COG5010   85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 310-541 1.10e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.54  E-value: 1.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 310 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNR-TALMALA-VSFTNESLQ--RQ 385
Cdd:cd24142   11 LDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyEKYLYLGqLSGGEEALQyyEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 386 ACETLRDWLRYTPAYAHLVAPGEEGAggvglgsSKRILGSLLS-------DSLFLE-----VKELFLAAVRLDPTSidPD 453
Cdd:cd24142   91 GIEILEEELQALQAASAEAEEEAEEL-------KRKLSSALCAlaeiymtDLCDEPdaeqrCEELITKALELDPTN--PE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 454 VQCGLGVLFNLSGEYDKAVDCFTAALSvrpddylLWNKLGATLANGNQSEEAvaayrrALELQPGYiRSRYNLGISCINL 533
Cdd:cd24142  162 ALQTLASLRISQQRPDEAKEALRRSLE-------LWKDLKEEDEEEAEEDEA------EEEDVPSY-EFRISLAKLLIEL 227


                 ....*...
gi 741927987 534 GAHREAVE 541
Cdd:cd24142  228 EMYEEALE 235
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 452-485 1.19e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.19e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 741927987   452 PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDD 485
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 333-550 2.91e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 91.98  E-value: 2.91e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 333 MEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVAPGEEGAG 412
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 413 GVGLGSSKRILGsllsdsLFLEVKELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKL 492
Cdd:COG3914   81 LELAALLLQALG------RYEEALALYRRALALNPDN--AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNL 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 741927987 493 GATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 550
Cdd:COG3914  153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 303-550 1.18e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 83.24  E-value: 1.18e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 303 FEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESL 382
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 383 QRQAcetlrdwlryTPAYAHLVAPGEEGAggvglgSSKRILGSL-LSDSLFLEVKELFLAAVRLDPTsiDPDVQCGLGVL 461
Cdd:COG2956   92 LDRA----------EELLEKLLELDPDDA------EALRLLAEIyEQEGDWEKAIEVLERLLKLGPE--NAHAYCELAEL 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 462 FNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVE 541
Cdd:COG2956  154 YLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALE 233


                 ....*....
gi 741927987 542 HFLEALNMQ 550
Cdd:COG2956  234 LLRKALELD 242
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
437-550 1.38e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 82.75  E-value: 1.38e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 437 ELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 516
Cdd:COG0457   29 EDYEKALELDPD--DAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELD 106

                         90       100       110
                 ....*....|....*....|....*....|....
gi 741927987 517 PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 550
Cdd:COG0457  107 PDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
326-548 4.83e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.82  E-value: 4.83e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 326 VQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQACEtlrdwlrytpayahlva 405
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALA----------------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 406 pgeegaggvglgsskrilgsllsdslflevkeLFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDD 485
Cdd:COG0457   64 --------------------------------DYEQALELDPD--DAEALNNLGLALQALGRYEEALEDYDKALELDPDD 109

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 741927987 486 YLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALN 548
Cdd:COG0457  110 AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEA 172
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
443-550 1.18e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.97  E-value: 1.18e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 443 VRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRS 522
Cdd:COG0457    1 LELDPD--DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA 78

                         90       100
                 ....*....|....*....|....*...
gi 741927987 523 RYNLGISCINLGAHREAVEHFLEALNMQ 550
Cdd:COG0457   79 LNNLGLALQALGRYEEALEDYDKALELD 106
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 305-526 2.86e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 75.80  E-value: 2.86e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 305 EGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLG----TTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNE 380
Cdd:COG3914    7 LALAALAAAALLAAAAAAELALAAELEAAALAAALGlallLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAAL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 381 SLQRQ-----ACETLRDWLRYTPAYAHLVApgeegaggvglgsskrILGSLLSDS-LFLEVKELFLAAVRLDPTsiDPDV 454
Cdd:COG3914   87 LLQALgryeeALALYRRALALNPDNAEALF----------------NLGNLLLALgRLEEALAALRRALALNPD--FAEA 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 741927987 455 QCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 526
Cdd:COG3914  149 YLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 434-547 3.51e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.84  E-value: 3.51e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 434 EVKELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRAL 513
Cdd:COG4783   22 EAEALLEKALELDPD--NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99

                         90       100       110
                 ....*....|....*....|....*....|....
gi 741927987 514 ELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 547
Cdd:COG4783  100 KLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
458-547 4.79e-14

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 71.87  E-value: 4.79e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 458 LGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHR 537
Cdd:COG4785   79 RGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYE 158

                         90
                 ....*....|
gi 741927987 538 EAVEHFLEAL 547
Cdd:COG4785  159 LAIADLEKAL 168
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 441-549 6.44e-14

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 68.88  E-value: 6.44e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 441 AAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYI 520
Cdd:COG4235    8 QALAANPN--DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                         90       100
                 ....*....|....*....|....*....
gi 741927987 521 RSRYNLGISCINLGAHREAVEHFLEALNM 549
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 310-547 3.34e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 72.81  E-value: 3.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  310 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFtneSLQRQACET 389
Cdd:TIGR02917  33 LQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAY---LLQGKFQQV 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  390 LRdwlrYTPAYAHLvaPGEEGAGGVGLgsskRILGSLLSDSLfLEVKELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYD 469
Cdd:TIGR02917 110 LD----ELPGKTLL--DDEGAAELLAL----RGLAYLGLGQL-ELAQKSYEQALAIDPRS--LYAKLGLAQLALAENRFD 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 741927987  470 KAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHfLEAL 547
Cdd:TIGR02917 177 EARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKH-ADAL 253
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 310-550 2.43e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 2.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 310 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGttQAENEQELL--AISALRKCLELKPDNRTALMALAVSFTNESLQRQAC 387
Cdd:COG2956   53 RRRGEYDRAIRIHQKLLERDPDRAEALLELA--QDYLKAGLLdrAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAI 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 388 ETLRDWLRYTPAYAHLVapgeegaggVGLGSSKRILGSllsdslFLEVKELFLAAVRLDPTSIDpdVQCGLGVLFNLSGE 467
Cdd:COG2956  131 EVLERLLKLGPENAHAY---------CELAELYLEQGD------YDEAIEALEKALKLDPDCAR--ALLLLAELYLEQGD 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 468 YDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGyIRSRYNLGISCINLGAHREAVEHFLEAL 547
Cdd:COG2956  194 YEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQL 272


                 ...
gi 741927987 548 NMQ 550
Cdd:COG2956  273 RRH 275
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 297-526 5.76e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 68.96  E-value: 5.76e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  297 RDHPQP-FEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAV 375
Cdd:TIGR02917 258 PNSPLAhYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLAS 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  376 SFTNESLQRQACETLRDWLR---------------------YTPAYAHLVAPGEEGAGGVGLGSSKRILGSLLSDSlfLE 434
Cdd:TIGR02917 338 IQLRLGRVDEAIATLSPALGldpddpaalsllgeaylalgdFEKAAEYLAKATELDPENAAARTQLGISKLSQGDP--SE 415

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  435 VKELFLAAVRLDPTSIDPDVQCGLGVLfnLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALE 514
Cdd:TIGR02917 416 AIADLETAAQLDPELGRADLLLILSYL--RSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALS 493

                         250
                  ....*....|..
gi 741927987  515 LQPGYIRSRYNL 526
Cdd:TIGR02917 494 IEPDFFPAAANL 505
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
466-554 6.22e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 59.03  E-value: 6.22e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 466 GEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVaAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLE 545
Cdd:COG3063    6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                 ....*....
gi 741927987 546 ALNMQRKSR 554
Cdd:COG3063   85 ALELDPSAL 93
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 458-550 6.66e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.59  E-value: 6.66e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 458 LGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHR 537
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                         90
                 ....*....|...
gi 741927987 538 EAVEHFLEALNMQ 550
Cdd:COG4783   90 EALALLEKALKLD 102
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 460-548 6.07e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 58.05  E-value: 6.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 460 VLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREA 539
Cdd:COG5010   62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141


                 ....*....
gi 741927987 540 VEHFLEALN 548
Cdd:COG5010  142 KAALQRALG 150
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 437-553 1.92e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.97  E-value: 1.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 437 ELFLAAVRLDPTSIDpdVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 516
Cdd:COG2956   29 DLLEEALELDPETVE--AHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELD 106

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 741927987 517 PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKS 553
Cdd:COG2956  107 PDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN 143
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 470-547 4.73e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.93  E-value: 4.73e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 741927987 470 KAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 547
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERAL 78
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 458-553 6.27e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.35  E-value: 6.27e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 458 LGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHR 537
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                         90
                 ....*....|....*.
gi 741927987 538 EAVEHFLEALNMQRKS 553
Cdd:COG2956   94 RAEELLEKLLELDPDD 109
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 437-553 1.14e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.58  E-value: 1.14e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 437 ELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 516
Cdd:COG2956   63 RIHQKLLERDPDR--AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLG 140

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 741927987 517 PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKS 553
Cdd:COG2956  141 PENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDC 177
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 318-485 1.21e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.77  E-value: 1.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 318 AVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQAcetlrdwlryt 397
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEA----------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 398 payahlvapgeegaggvglgsskrilgsllsdslflevKELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTA 477
Cdd:COG4235   71 --------------------------------------EELLERALALDPD--NPEALYLLGLAAFQQGDYAEAIAAWQK 110


                 ....*...
gi 741927987 478 ALSVRPDD 485
Cdd:COG4235  111 LLALLPAD 118
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
439-559 1.41e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 52.61  E-value: 1.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 439 FLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPG 518
Cdd:COG4785   96 FDQALELDPDL--AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPN 173

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 741927987 519 YIRSRYNLGISCINLGAHrEAVEHFLEALNMQRKSRGPRGE 559
Cdd:COG4785  174 DPERALWLYLAERKLDPE-KALALLLEDWATAYLLQGDTEE 213
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 432-517 3.29e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 50.34  E-value: 3.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 432 FLEVKELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRR 511
Cdd:COG5010   70 FEESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147


                 ....*.
gi 741927987 512 ALELQP 517
Cdd:COG5010  148 ALGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 437-519 3.72e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 3.72e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 437 ELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 516
Cdd:COG4783   59 VLLHEALELDPD--EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136


                 ...
gi 741927987 517 PGY 519
Cdd:COG4783  137 PDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 297-401 1.34e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.88  E-value: 1.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 297 RDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVS 376
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100
                 ....*....|....*....|....*
gi 741927987 377 FTNESLQRQACETLRDWLRYTPAYA 401
Cdd:COG4783   82 LLKAGDYDEALALLEKALKLDPEHP 106
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
436-517 2.20e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.32  E-value: 2.20e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 436 KELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDcFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALEL 515
Cdd:COG3063   12 EEYYEKALELDPD--NADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALEL 88


                 ..
gi 741927987 516 QP 517
Cdd:COG3063   89 DP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 310-552 2.44e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 2.44e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  310 LQEGDLPNAVLLFEAAVQQDPKHMEAWQ-----------------YLGTTQAENEQEL-----------------LAISA 355
Cdd:TIGR02917 510 IQEGNPDDAIQRFEKVLTIDPKNLRAILalaglylrtgneeeavaWLEKAAELNPQEIepalalaqyylgkgqlkKALAI 589

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  356 LRKCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYTP---------AYAHLVAPGEEGAggvgLGSSKRilgSL 426
Cdd:TIGR02917 590 LNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsalallllADAYAVMKNYAKA----ITSLKR---AL 662

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  427 LSDSLFLEVK----ELFLAAVRLDPT-----------SIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNK 491
Cdd:TIGR02917 663 ELKPDNTEAQiglaQLLLAAKRTESAkkiakslqkqhPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKL 742

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 741927987  492 LGATLANGNQSEeAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRK 552
Cdd:TIGR02917 743 HRALLASGNTAE-AVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPD 802
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 437-517 2.97e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 2.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 437 ELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 516
Cdd:COG4235   38 AAYEKALRLDPD--NADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALL 115


                 .
gi 741927987 517 P 517
Cdd:COG4235  116 P 116
TPR_12 pfam13424
Tetratricopeptide repeat;
488-552 4.00e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.07  E-value: 4.00e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 741927987  488 LWNKLGATLANGNQSEEAVAAYRRALELQ--------PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRK 552
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 310-400 6.22e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.95  E-value: 6.22e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 310 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQACET 389
Cdd:COG4783   49 LQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAA 128

                         90
                 ....*....|.
gi 741927987 390 LRDWLRYTPAY 400
Cdd:COG4783  129 LEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 303-405 7.55e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.80  E-value: 7.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 303 FEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESL 382
Cdd:COG2956  148 CELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGD 227

                         90       100
                 ....*....|....*....|...
gi 741927987 383 QRQACETLRDWLRYTPAYAHLVA 405
Cdd:COG2956  228 PEEALELLRKALELDPSDDLLLA 250
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 310-401 1.13e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.00  E-value: 1.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 310 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQACET 389
Cdd:COG4235   28 LRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAA 107

                         90
                 ....*....|..
gi 741927987 390 LRDWLRYTPAYA 401
Cdd:COG4235  108 WQKLLALLPADA 119
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 250-398 1.24e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 1.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 250 DFWDKLQAELEEMAKRDAEAHPWLSDHDDLTSASYDKGYHFEEENPLRDHPQPFEEGLRRLqeGDLPNAVLLFEAAVQQD 329
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKL--GDFEESLALLEQALQLD 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 741927987 330 PKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYTP 398
Cdd:COG5010   85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
303-377 1.81e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.45  E-value: 1.81e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 741927987 303 FEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSF 377
Cdd:COG4785   77 YERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIAL 151
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
310-399 1.90e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.62  E-value: 1.90e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 310 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAIsALRKCLELKPDNRTALMALAVSFTNESLQRQACET 389
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                         90
                 ....*....|
gi 741927987 390 LRDWLRYTPA 399
Cdd:COG3063   82 LERALELDPS 91
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
306-446 2.32e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 46.15  E-value: 2.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 306 GLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQ 385
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 741927987 386 ACETLRDWLRYTPAYAHLVAPGEEGAGGVGLGSSKRILGSLLSDSLFLEVKELFLAAVRLD 446
Cdd:COG0457  163 ALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELL 223
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 309-371 2.45e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 2.45e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 741927987 309 RLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALM 371
Cdd:COG4235   61 LLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARL 123
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 465-548 2.52e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.83  E-value: 2.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 465 SGEYDKAVDCFTAALSVRPDDYLLWN---KLGATLANGNQSEEAVAAYRRALELQPGYIR---SRYNLGISCINLGAHRE 538
Cdd:COG1729    6 AGDYDEAIAAFKAFLKRYPNSPLAPDalyWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDK 85

                         90
                 ....*....|
gi 741927987 539 AVEHFLEALN 548
Cdd:COG1729   86 ARATLEELIK 95
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
482-547 2.64e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 45.68  E-value: 2.64e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 741927987 482 RPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 547
Cdd:COG4785   69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 477-583 3.66e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.18  E-value: 3.66e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 477 AALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKsrgp 556
Cdd:COG5010   45 AGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---- 120

                         90       100
                 ....*....|....*....|....*..
gi 741927987 557 rgeggamSENIWSTLRLALSMLGQSDA 583
Cdd:COG5010  121 -------NPNAYSNLAALLLSLGQDDE 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
306-401 4.59e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.38  E-value: 4.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 306 GLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQ 385
Cdd:COG0457   49 GLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128

                         90
                 ....*....|....*.
gi 741927987 386 ACETLRDWLRYTPAYA 401
Cdd:COG0457  129 AIEAYERALELDPDDA 144
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 310-518 7.77e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 44.90  E-value: 7.77e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 310 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTT--QAENEQELLAI-SALRKCLELKPDNRTALMALAVSftnESLQRQA 386
Cdd:COG3071   96 LDQGQAEQALATLEALRAGAPRHPQVLRLLLQAyrQLGDWEELLELlPALRKHKALSAEEAQALERRAYL---GLLRQAA 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 387 --CETLRDW-------LRYTPAYA-----HLVAPGEEG-AGGVGLGSSKRI----LGSLLSDSLFLEVKELFL---AAVR 444
Cdd:COG3071  173 rdAEALKALwkalpraERRDPELAaayarALIALGDHDeAERLLREALKRQwdprLVRLYGRLQGGDPAKQLKraeKWLK 252

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 741927987 445 LDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPD--DYLLwnkLGATLANGNQSEEAVAAYRRALELQPG 518
Cdd:COG3071  253 KHPN--DPDLLLALGRLCLRNQLWGKAREYLEAALALRPSaeAYAE---LARLLEQLGDPEEAAEHYRKALALALG 323
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 310-541 1.10e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.54  E-value: 1.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 310 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNR-TALMALA-VSFTNESLQ--RQ 385
Cdd:cd24142   11 LDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyEKYLYLGqLSGGEEALQyyEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 386 ACETLRDWLRYTPAYAHLVAPGEEGAggvglgsSKRILGSLLS-------DSLFLE-----VKELFLAAVRLDPTSidPD 453
Cdd:cd24142   91 GIEILEEELQALQAASAEAEEEAEEL-------KRKLSSALCAlaeiymtDLCDEPdaeqrCEELITKALELDPTN--PE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 454 VQCGLGVLFNLSGEYDKAVDCFTAALSvrpddylLWNKLGATLANGNQSEEAvaayrrALELQPGYiRSRYNLGISCINL 533
Cdd:cd24142  162 ALQTLASLRISQQRPDEAKEALRRSLE-------LWKDLKEEDEEEAEEDEA------EEEDVPSY-EFRISLAKLLIEL 227


                 ....*...
gi 741927987 534 GAHREAVE 541
Cdd:cd24142  228 EMYEEALE 235
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 310-548 2.87e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.92  E-value: 2.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  310 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTA-LMALAVSFTNEslQRQACE 388
Cdd:TIGR02917 680 LAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAiKLHRALLASGN--TAEAVK 757

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  389 TLRDWLRYTPAYAhlvapgeegaggvglgsskrILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEY 468
Cdd:TIGR02917 758 TLEAWLKTHPNDA--------------------VLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLEL 817

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  469 D--KAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEA 546
Cdd:TIGR02917 818 KdpRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARKELDKL 897


                  ..
gi 741927987  547 LN 548
Cdd:TIGR02917 898 LN 899
TPR_1 pfam00515
Tetratricopeptide repeat;
452-485 5.00e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.79  E-value: 5.00e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 741927987  452 PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDD 485
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 452-485 1.19e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.19e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 741927987   452 PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPDD 485
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 310-391 2.11e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.05  E-value: 2.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 310 LQEGDLPNAVLLFEAAVQQDPKHM---EAWQYLGTTQAENEQELLAISALRKCLELKPDNRT---ALMALAVSFTNESLQ 383
Cdd:COG1729    4 LKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDY 83


                 ....*...
gi 741927987 384 RQACETLR 391
Cdd:COG1729   84 DKARATLE 91
TPR_12 pfam13424
Tetratricopeptide repeat;
454-515 3.51e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.60  E-value: 3.51e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  454 VQCGLGVLFNLSGEYDKAVDCFTAALSV--------RPDDYLLWNKLGATLANGNQSEEAVAAYRRALEL 515
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
TPR_11 pfam13414
TPR repeat;
500-527 3.75e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.53  E-value: 3.75e-03
                          10        20
                  ....*....|....*....|....*...
gi 741927987  500 NQSEEAVAAYRRALELQPGYIRSRYNLG 527
Cdd:pfam13414   8 GKYEEAIEAYKKALKLDPDNPEAYYNLG 35
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 434-518 4.40e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 4.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987 434 EVKELFLAAVRLDPTS-IDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPD-----DYLLwnKLGATLANGNQSEEAVA 507
Cdd:COG1729   11 EAIAAFKAFLKRYPNSpLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkapDALL--KLGLSYLELGDYDKARA 88

                         90
                 ....*....|.
gi 741927987 508 AYRRALELQPG 518
Cdd:COG1729   89 TLEELIKKYPD 99
LcrH_SycD TIGR02552
type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in ...
 465-573 4.52e-03

type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array.


Pssm-ID: 274197 [Multi-domain]  Cd Length: 135  Bit Score: 37.66  E-value: 4.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 741927987  465 SGEYDKAVDCFTAALSVRPDDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 544
Cdd:TIGR02552  30 QGRYDEALKLFQLLAAYDPYNSRYWLGLAACCQMLKEYEEAIDAYALAAALDPDDPRPYFHAAECLLALGEPESALKALD 109

                          90       100
                  ....*....|....*....|....*....
gi 741927987  545 EALNMQRKSRgprgEGGAMSENIWSTLRL 573
Cdd:TIGR02552 110 LAIEICGENP----EYSELKERAEAMLES 134
TPR_1 pfam00515
Tetratricopeptide repeat;
489-519 4.62e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.09  E-value: 4.62e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 741927987  489 WNKLGATLANGNQSEEAVAAYRRALELQPGY 519
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 489-554 4.86e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 4.86e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 741927987 489 WNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSR 554
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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