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Conserved domains on  [gi|721631826|ref|XP_010230477|]
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translocon-associated protein subunit beta [Brachypodium distachyon]

Protein Classification

translocon-associated protein subunit beta( domain architecture ID 12065704)

translocon-associated protein subunit beta is part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins

Gene Ontology:  GO:0006613
PubMed:  28218252

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TRAP_beta pfam05753
Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic ...
 18-190 1.04e-53

Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic translocon-associated protein beta (TRAPB) or signal sequence receptor beta subunit (SSR-beta) proteins. The normal translocation of nascent polypeptides into the lumen of the endoplasmic reticulum (ER) is thought to be aided in part by a translocon-associated protein (TRAP) complex consisting of 4 protein subunits. The association of mature proteins with the ER and Golgi, or other intracellular locales, such as lysosomes, depends on the initial targeting of the nascent polypeptide to the ER membrane. A similar scenario must also exist for proteins destined for secretion.


:

Pssm-ID: 399046  Cd Length: 178  Bit Score: 169.06  E-value: 1.04e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721631826   18 FTATAAGDAPFIVAHKKVALSRPKPGVERLAVSLDLYNQGSATAYDVAITDDSWPKEAFELVSGEVSKTLERLDPGATAS 97
Cdd:pfam05753   8 LAALAQDDAPARLLVKKKILNRYLVEGRDLTVTYTIYNVGSSAAYDVSLVDNSFPEEAFEVVSGSLSASWERLAPGSNVS 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721631826   98 HVFVLETKAQGRFQGSPAVIKYRVPTKAV-LQEAFSTPILALDILAERPPVKKFEWAkklVAKYGALVSVVSFVAAFIYL 176
Cdd:pfam05753  88 HIFVVEPKKSGYFNFTAAEVTYRPSEDGAeLQVAYSSPPGEGGIFAERDYGKKFSLH---LLDWVAFAVMTLPSLGIPYL 164

                         170
                  ....*....|....
gi 721631826  177 VASPSKSGGAKAGK 190
Cdd:pfam05753 165 LWWVSKSKYETSKK 178
 
Name Accession Description Interval E-value
TRAP_beta pfam05753
Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic ...
 18-190 1.04e-53

Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic translocon-associated protein beta (TRAPB) or signal sequence receptor beta subunit (SSR-beta) proteins. The normal translocation of nascent polypeptides into the lumen of the endoplasmic reticulum (ER) is thought to be aided in part by a translocon-associated protein (TRAP) complex consisting of 4 protein subunits. The association of mature proteins with the ER and Golgi, or other intracellular locales, such as lysosomes, depends on the initial targeting of the nascent polypeptide to the ER membrane. A similar scenario must also exist for proteins destined for secretion.


Pssm-ID: 399046  Cd Length: 178  Bit Score: 169.06  E-value: 1.04e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721631826   18 FTATAAGDAPFIVAHKKVALSRPKPGVERLAVSLDLYNQGSATAYDVAITDDSWPKEAFELVSGEVSKTLERLDPGATAS 97
Cdd:pfam05753   8 LAALAQDDAPARLLVKKKILNRYLVEGRDLTVTYTIYNVGSSAAYDVSLVDNSFPEEAFEVVSGSLSASWERLAPGSNVS 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721631826   98 HVFVLETKAQGRFQGSPAVIKYRVPTKAV-LQEAFSTPILALDILAERPPVKKFEWAkklVAKYGALVSVVSFVAAFIYL 176
Cdd:pfam05753  88 HIFVVEPKKSGYFNFTAAEVTYRPSEDGAeLQVAYSSPPGEGGIFAERDYGKKFSLH---LLDWVAFAVMTLPSLGIPYL 164

                         170
                  ....*....|....
gi 721631826  177 VASPSKSGGAKAGK 190
Cdd:pfam05753 165 LWWVSKSKYETSKK 178
MJ0795 COG1361
S-layer protein MJ0795, predicted component of type IV pili-like system [General function ...
 17-104 7.41e-03

S-layer protein MJ0795, predicted component of type IV pili-like system [General function prediction only];


Pssm-ID: 440972 [Multi-domain]  Cd Length: 409  Bit Score: 36.60  E-value: 7.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721631826  17 SFTATAAGDAPFIVAHKKVALSRPKPGVerlaVSLDLYNQGSATAYDVAITDDSwpkeAFELVSGEVSKTLERLDPGATA 96
Cdd:COG1361  261 TIGVYVAPKADFEVENVESTITAGETVT----ITITVTNTGNETAKNVVARLSA----DDPLSSLDDEAFIGDLAPGESA 332


                 ....*...
gi 721631826  97 SHVFVLET 104
Cdd:COG1361  333 TVTFTVSA 340
 
Name Accession Description Interval E-value
TRAP_beta pfam05753
Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic ...
 18-190 1.04e-53

Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic translocon-associated protein beta (TRAPB) or signal sequence receptor beta subunit (SSR-beta) proteins. The normal translocation of nascent polypeptides into the lumen of the endoplasmic reticulum (ER) is thought to be aided in part by a translocon-associated protein (TRAP) complex consisting of 4 protein subunits. The association of mature proteins with the ER and Golgi, or other intracellular locales, such as lysosomes, depends on the initial targeting of the nascent polypeptide to the ER membrane. A similar scenario must also exist for proteins destined for secretion.


Pssm-ID: 399046  Cd Length: 178  Bit Score: 169.06  E-value: 1.04e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721631826   18 FTATAAGDAPFIVAHKKVALSRPKPGVERLAVSLDLYNQGSATAYDVAITDDSWPKEAFELVSGEVSKTLERLDPGATAS 97
Cdd:pfam05753   8 LAALAQDDAPARLLVKKKILNRYLVEGRDLTVTYTIYNVGSSAAYDVSLVDNSFPEEAFEVVSGSLSASWERLAPGSNVS 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721631826   98 HVFVLETKAQGRFQGSPAVIKYRVPTKAV-LQEAFSTPILALDILAERPPVKKFEWAkklVAKYGALVSVVSFVAAFIYL 176
Cdd:pfam05753  88 HIFVVEPKKSGYFNFTAAEVTYRPSEDGAeLQVAYSSPPGEGGIFAERDYGKKFSLH---LLDWVAFAVMTLPSLGIPYL 164

                         170
                  ....*....|....
gi 721631826  177 VASPSKSGGAKAGK 190
Cdd:pfam05753 165 LWWVSKSKYETSKK 178
MJ0795 COG1361
S-layer protein MJ0795, predicted component of type IV pili-like system [General function ...
 17-104 7.41e-03

S-layer protein MJ0795, predicted component of type IV pili-like system [General function prediction only];


Pssm-ID: 440972 [Multi-domain]  Cd Length: 409  Bit Score: 36.60  E-value: 7.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721631826  17 SFTATAAGDAPFIVAHKKVALSRPKPGVerlaVSLDLYNQGSATAYDVAITDDSwpkeAFELVSGEVSKTLERLDPGATA 96
Cdd:COG1361  261 TIGVYVAPKADFEVENVESTITAGETVT----ITITVTNTGNETAKNVVARLSA----DDPLSSLDDEAFIGDLAPGESA 332


                 ....*...
gi 721631826  97 SHVFVLET 104
Cdd:COG1361  333 TVTFTVSA 340
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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