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Conserved domains on  [gi|688616512|ref|XP_009296180|]
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centrosomal protein of 290 kDa isoform X3 [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CEP209_CC5 pfam16574
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ...
 1272-1399 1.28e-45

Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.


:

Pssm-ID: 465184 [Multi-domain]  Cd Length: 128  Bit Score: 161.40  E-value: 1.28e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1272 TMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQ 1351
Cdd:pfam16574    1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 688616512  1352 REEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLER 1399
Cdd:pfam16574   81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1118-1985 4.60e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.14  E-value: 4.60e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1118 RKRITE--LEKTEANLRievsklrEVSDVAKmqvsaldarqqSREKEVESLRRQVLDYQAESDEKALIAKLHQHIVALQL 1195
Cdd:TIGR02168  173 RRKETErkLERTRENLD-------RLEDILN-----------ELERQLKSLERQAEKAERYKELKAELRELELALLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1196 -SETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRrqfsgalplAQQEKFSNTML 1274
Cdd:TIGR02168  235 eELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA---------NEISRLEQQKQ 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1275 HLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQ--KVSEWHKKLEDVRLLEMRQSRELNTQR 1352
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeaELEELEAELEELESRLEELEEQLETLR 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1353 EEIKYLKNCVAEQERTISGLEEELVQqnnlLEERQLIWDQREVQLERQLDSYEKQ--QNEVLNTAQKFEEATGSLPDPNQ 1430
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLER----LEDRRERLQQEIEELLKKLEEAELKelQAELEELEEELEELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1431 planqldyALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLrlpAAAEREKLLADLSKQED 1510
Cdd:TIGR02168  462 --------ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK---NQSGLSGILGVLSELIS 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1511 SESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLgkarqEQEEIAKRHEEEVRALH----QKLDVYMDTSLDRFKQTAL 1586
Cdd:TIGR02168  531 VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFL-----KQNELGRVTFLPLDSIKgteiQGNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1587 ELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLE-----DKHAAQ 1661
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILErrreiEELEEK 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1662 MKGLSQEAEELRAQLIQMEKELHYLRTELEA--QKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTS 1739
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQlrKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1740 QAEQQIITNAAQKEEALNVQQivdkqtkelracvrdLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQ 1819
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEE---------------LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1820 SEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPAdkRSTLKEDKSSKEEVVRweeg 1899
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA--LALLRSELEELSEELR---- 904

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1900 kkwqarvdKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAE 1979
Cdd:TIGR02168  905 --------ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976


                   ....*.
gi 688616512  1980 LEQQIK 1985
Cdd:TIGR02168  977 LENKIK 982
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 87-869 1.01e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 1.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    87 KVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQL 166
Cdd:TIGR02168  214 RYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   167 TRKNEQLQQDIEFYRKEAEQ---------RESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKN 237
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANlerqleeleAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   238 LEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvmaAVNAKVEEWKSVLSGKDL 317
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK------LEEAELKELQAELEELEE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   318 EILEYQQMIRDLREKLRTAQMDSDKsniiaLQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDH 397
Cdd:TIGR02168  448 ELEELQEELERLEEALEELREELEE-----AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   398 QRRLEDLS--AKLQVAERKVLEAQRAAQLAE-----RDARDKDKElNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVR 470
Cdd:TIGR02168  523 GVLSELISvdEGYEAAIEAALGGRLQAVVVEnlnaaKKAIAFLKQ-NELGRVTFLPLDSIKGTEIQGNDREILKNIEGFL 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   471 DREIEgMIKEINQLEMKINNLLDE---NEDLRERLGLNPKEE-------LDLSEFRRSKILKQRQYKAENQVLLKEIERL 540
Cdd:TIGR02168  602 GVAKD-LVKFDPKLRKALSYLLGGvlvVDDLDNALELAKKLRpgyrivtLDGDLVRPGGVITGGSAKTNSSILERRREIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   541 EEERLELKQRIRALVKDKGVTVVSNSLLDNSVEEKPVRSLRPSSGSTDDEIKRKNERLQKELSNKEKELELRRSESTQFK 620
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   621 AKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGvSIPSLERLVNALEMKYSEgkfdaslhLRTQVDQLTGRNEELRQ 700
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE-ELKALREALDELRAELTL--------LNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   701 EMKTAREEAANTLSQLTKANEKIARLESEMESMskstgssiphktlalpEEMTPTSAEAINALNEYTVQLLQEIKNKGDS 780
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEEL----------------EELIEELESELEALLNERASLEEALALLRSE 895

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   781 IEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVDAVKIKEynhLLETLEKDPSEIRR 860
Cdd:TIGR02168  896 LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEA---LENKIEDDEEEARR 972


                   ....*....
gi 688616512   861 EMAETGRKI 869
Cdd:TIGR02168  973 RLKRLENKI 981
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1774-2643 8.58e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 8.58e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1774 RDLNEELQLAKdgVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVEsdgpT 1853
Cdd:TIGR02168  216 KELKAELRELE--LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK----E 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1854 VDALQKKIRKLEHELDRKSisepaDKRSTLKEDKSSKEEVvrweegkkwqarvdkmrnvLKEKEREVDSQAKQLATMKEL 1933
Cdd:TIGR02168  290 LYALANEISRLEQQKQILR-----ERLANLERQLEELEAQ-------------------LEELESKLDELAEELAELEEK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1934 YSRLEQEKVSLQKKLKgrgvtadqvvgartlEADKEIEELHKRNAELEQQIKVMKQQQALPRdAAMEDITNRNRYLEERL 2013
Cdd:TIGR02168  346 LEELKEELESLEAELE---------------ELEAELEELESRLEELEEQLETLRSKVAQLE-LQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2014 YSMESRLSKeppsrpsdrhstspsqlswsskvrsmtfdvieaeqtqssllnstvvvTEKEISVIEDKATQTSFRSIDMGT 2093
Cdd:TIGR02168  410 ERLEDRRER-----------------------------------------------LQQEIEELLKKLEEAELKELQAEL 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2094 AEVNQDDENVAKNKIDLEQKAlmkddktEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELT 2173
Cdd:TIGR02168  443 EELEEELEELQEELERLEEAL-------EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2174 HREMMEKPLDEDQLEVENE-ETNAEEMLYSTMNQaeletpkVLLEGDEDYGQEPEELLKCECDPSAESKELDEEETALSN 2252
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGyEAAIEAALGGRLQA-------VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQG 588

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2253 STTFDAKLVSEQPAMEKNKSFTP---EAGFNPNLSEVSTSREL-NANTENDILGHLKAKVTRLNDKEHSMKSKARKTSGR 2328
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDpklRKALSYLLGGVLVVDDLdNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKT 668

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2329 GSDTPSQR----------------EHEFQKENLRLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKR 2392
Cdd:TIGR02168  669 NSSILERRreieeleekieeleekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2393 LNHLRGsgrsgktipELEKTIGLMKKVVEKVQRENENLKRTSE--VNVQEQLATLERDHEKLKSEYEKLKGKQEE----- 2465
Cdd:TIGR02168  749 IAQLSK---------ELTELEAEIEELEERLEEAEEELAEAEAeiEELEAQIEQLKEELKALREALDELRAELTLlneea 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2466 -QLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEEthqrlLLAQSKGATLLGVDSKT 2544
Cdd:TIGR02168  820 aNLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-----LLNERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2545 WKSSVvtrlfENKMKGLESDIAKKNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNVpveatTDEGLAREYQSVR 2624
Cdd:TIGR02168  895 ELEEL-----SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL-----TLEEAEALENKIE 964

                          890
                   ....*....|....*....
gi 688616512  2625 LANKQLEREKAQLLRQIQR 2643
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKE 983
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
988-1217 1.98e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  988 ERIDSINKELEISKEKLHTLEQAFEnisttggeiimdkatkavANSEIVSVSRRITTLEmkELNERQRAEHAQKMYEHLR 1067
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEPIRE------------------LAERYAAARERLAELE--YLRAALRLWFAQRRLELLE 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1068 NSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSvskhisdaDRKRITELEKTEANLRIEVSKLREVSDVAKM 1147
Cdd:COG4913   295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGN--------GGDRLEQLEREIERLERELEERERRRARLEA 366

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1148 QVSALDARQQSREKEVESLRRQVldyqaesdeKALIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQ 1217
Cdd:COG4913   367 LLAALGLPLPASAEEFAALRAEA---------AALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
 
Name Accession Description Interval E-value
CEP209_CC5 pfam16574
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ...
 1272-1399 1.28e-45

Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.


Pssm-ID: 465184 [Multi-domain]  Cd Length: 128  Bit Score: 161.40  E-value: 1.28e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1272 TMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQ 1351
Cdd:pfam16574    1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 688616512  1352 REEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLER 1399
Cdd:pfam16574   81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1118-1985 4.60e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.14  E-value: 4.60e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1118 RKRITE--LEKTEANLRievsklrEVSDVAKmqvsaldarqqSREKEVESLRRQVLDYQAESDEKALIAKLHQHIVALQL 1195
Cdd:TIGR02168  173 RRKETErkLERTRENLD-------RLEDILN-----------ELERQLKSLERQAEKAERYKELKAELRELELALLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1196 -SETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRrqfsgalplAQQEKFSNTML 1274
Cdd:TIGR02168  235 eELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA---------NEISRLEQQKQ 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1275 HLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQ--KVSEWHKKLEDVRLLEMRQSRELNTQR 1352
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeaELEELEAELEELESRLEELEEQLETLR 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1353 EEIKYLKNCVAEQERTISGLEEELVQqnnlLEERQLIWDQREVQLERQLDSYEKQ--QNEVLNTAQKFEEATGSLPDPNQ 1430
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLER----LEDRRERLQQEIEELLKKLEEAELKelQAELEELEEELEELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1431 planqldyALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLrlpAAAEREKLLADLSKQED 1510
Cdd:TIGR02168  462 --------ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK---NQSGLSGILGVLSELIS 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1511 SESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLgkarqEQEEIAKRHEEEVRALH----QKLDVYMDTSLDRFKQTAL 1586
Cdd:TIGR02168  531 VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFL-----KQNELGRVTFLPLDSIKgteiQGNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1587 ELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLE-----DKHAAQ 1661
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILErrreiEELEEK 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1662 MKGLSQEAEELRAQLIQMEKELHYLRTELEA--QKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTS 1739
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQlrKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1740 QAEQQIITNAAQKEEALNVQQivdkqtkelracvrdLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQ 1819
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEE---------------LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1820 SEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPAdkRSTLKEDKSSKEEVVRweeg 1899
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA--LALLRSELEELSEELR---- 904

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1900 kkwqarvdKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAE 1979
Cdd:TIGR02168  905 --------ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976


                   ....*.
gi 688616512  1980 LEQQIK 1985
Cdd:TIGR02168  977 LENKIK 982
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1200-1870 1.81e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 1.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1200 AISRLEATNTRLQKLEAqkLRDEqkLDEQQQALwhARQeghqrARhlrhtiQALR-RQFSGALPLAQQEKFSNTMLHLQE 1278
Cdd:COG1196   177 AERKLEATEENLERLED--ILGE--LERQLEPL--ERQ-----AE------KAERyRELKEELKELEAELLLLKLRELEA 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1279 DRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDakgaqkvsEWHKKLEDVRLLEMRQSRELNTQREEikyl 1358
Cdd:COG1196   240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL--------ELEEAQAEEYELLAELARLEQDIARL---- 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1359 kncvAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLpdpnqplANQLDY 1438
Cdd:COG1196   308 ----EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA-------EAELAE 376

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1439 ALGKIKEHVRTILETKTTCKILEEKLKEKEAAlwssEQNVLSRDKVINELRLRLPAAAEREKLLADLSKQEDSESQPTLK 1518
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQLEELEEA----EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1519 VAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEvRALHQKLDVYMDTSLDRFKQTALELIKKPTITVPT 1598
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL-LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1599 SKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAmeHAADMARLEDKHAAQMKGLSQEAEELRAQLIQ 1678
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL--PLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1679 MEKELHYLRTELEAQKEANVRspsntmknlverlknQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNV 1758
Cdd:COG1196   610 EADARYYVLGDTLLGRTLVAA---------------RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL 674

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1759 QQIVDKQTKELRACVRDLNEElqlakdgvRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQR 1838
Cdd:COG1196   675 LEAEAELEELAERLAEEELEL--------EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746

                         650       660       670
                  ....*....|....*....|....*....|..
gi 688616512 1839 LSSGLQAQVESDGPTVDALQKKIRKLEHELDR 1870
Cdd:COG1196   747 LLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 87-869 1.01e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 1.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    87 KVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQL 166
Cdd:TIGR02168  214 RYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   167 TRKNEQLQQDIEFYRKEAEQ---------RESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKN 237
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANlerqleeleAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   238 LEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvmaAVNAKVEEWKSVLSGKDL 317
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK------LEEAELKELQAELEELEE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   318 EILEYQQMIRDLREKLRTAQMDSDKsniiaLQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDH 397
Cdd:TIGR02168  448 ELEELQEELERLEEALEELREELEE-----AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   398 QRRLEDLS--AKLQVAERKVLEAQRAAQLAE-----RDARDKDKElNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVR 470
Cdd:TIGR02168  523 GVLSELISvdEGYEAAIEAALGGRLQAVVVEnlnaaKKAIAFLKQ-NELGRVTFLPLDSIKGTEIQGNDREILKNIEGFL 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   471 DREIEgMIKEINQLEMKINNLLDE---NEDLRERLGLNPKEE-------LDLSEFRRSKILKQRQYKAENQVLLKEIERL 540
Cdd:TIGR02168  602 GVAKD-LVKFDPKLRKALSYLLGGvlvVDDLDNALELAKKLRpgyrivtLDGDLVRPGGVITGGSAKTNSSILERRREIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   541 EEERLELKQRIRALVKDKGVTVVSNSLLDNSVEEKPVRSLRPSSGSTDDEIKRKNERLQKELSNKEKELELRRSESTQFK 620
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   621 AKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGvSIPSLERLVNALEMKYSEgkfdaslhLRTQVDQLTGRNEELRQ 700
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE-ELKALREALDELRAELTL--------LNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   701 EMKTAREEAANTLSQLTKANEKIARLESEMESMskstgssiphktlalpEEMTPTSAEAINALNEYTVQLLQEIKNKGDS 780
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEEL----------------EELIEELESELEALLNERASLEEALALLRSE 895

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   781 IEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVDAVKIKEynhLLETLEKDPSEIRR 860
Cdd:TIGR02168  896 LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEA---LENKIEDDEEEARR 972


                   ....*....
gi 688616512   861 EMAETGRKI 869
Cdd:TIGR02168  973 RLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 110-698 1.55e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 1.55e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  110 LRDEIRQLESHLERKEKEVTQLEK----EMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAE 185
Cdd:COG1196   191 LEDILGELERQLEPLERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  186 QRES--LQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTD 263
Cdd:COG1196   271 ELRLelEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  264 AIMDQLRKDRDHAKLQVRELTDQIQARVEEDDpvmaAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQmdsdkS 343
Cdd:COG1196   351 EELEEAEAELAEAEEALLEAEAELAEAEEELE----ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE-----E 421

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  344 NIIALQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKV---LEAQR 420
Cdd:COG1196   422 ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLlllLEAEA 501

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  421 AAQLAERDARDKDKELNDTLSRIRLYESGTDGLE----AAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENE 496
Cdd:COG1196   502 DYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDK 581

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  497 DLRERLGLNPKEELDLSEFRRSKILKQRQYKAENQVLLKEIERLEEERLELKQRIRALVKDKGVTVVSnSLLDNSVEEKP 576
Cdd:COG1196   582 IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREV-TLEGEGGSAGG 660

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  577 VRSLRpsSGSTDDEIKRKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTG 656
Cdd:COG1196   661 SLTGG--SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|..
gi 688616512  657 VSIPSLERLVNALEMKYSEGKFDASlHLRTQVDQLTGRNEEL 698
Cdd:COG1196   739 EELLEEEELLEEEALEELPEPPDLE-ELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1774-2643 8.58e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 8.58e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1774 RDLNEELQLAKdgVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVEsdgpT 1853
Cdd:TIGR02168  216 KELKAELRELE--LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK----E 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1854 VDALQKKIRKLEHELDRKSisepaDKRSTLKEDKSSKEEVvrweegkkwqarvdkmrnvLKEKEREVDSQAKQLATMKEL 1933
Cdd:TIGR02168  290 LYALANEISRLEQQKQILR-----ERLANLERQLEELEAQ-------------------LEELESKLDELAEELAELEEK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1934 YSRLEQEKVSLQKKLKgrgvtadqvvgartlEADKEIEELHKRNAELEQQIKVMKQQQALPRdAAMEDITNRNRYLEERL 2013
Cdd:TIGR02168  346 LEELKEELESLEAELE---------------ELEAELEELESRLEELEEQLETLRSKVAQLE-LQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2014 YSMESRLSKeppsrpsdrhstspsqlswsskvrsmtfdvieaeqtqssllnstvvvTEKEISVIEDKATQTSFRSIDMGT 2093
Cdd:TIGR02168  410 ERLEDRRER-----------------------------------------------LQQEIEELLKKLEEAELKELQAEL 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2094 AEVNQDDENVAKNKIDLEQKAlmkddktEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELT 2173
Cdd:TIGR02168  443 EELEEELEELQEELERLEEAL-------EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2174 HREMMEKPLDEDQLEVENE-ETNAEEMLYSTMNQaeletpkVLLEGDEDYGQEPEELLKCECDPSAESKELDEEETALSN 2252
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGyEAAIEAALGGRLQA-------VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQG 588

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2253 STTFDAKLVSEQPAMEKNKSFTP---EAGFNPNLSEVSTSREL-NANTENDILGHLKAKVTRLNDKEHSMKSKARKTSGR 2328
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDpklRKALSYLLGGVLVVDDLdNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKT 668

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2329 GSDTPSQR----------------EHEFQKENLRLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKR 2392
Cdd:TIGR02168  669 NSSILERRreieeleekieeleekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2393 LNHLRGsgrsgktipELEKTIGLMKKVVEKVQRENENLKRTSE--VNVQEQLATLERDHEKLKSEYEKLKGKQEE----- 2465
Cdd:TIGR02168  749 IAQLSK---------ELTELEAEIEELEERLEEAEEELAEAEAeiEELEAQIEQLKEELKALREALDELRAELTLlneea 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2466 -QLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEEthqrlLLAQSKGATLLGVDSKT 2544
Cdd:TIGR02168  820 aNLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-----LLNERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2545 WKSSVvtrlfENKMKGLESDIAKKNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNVpveatTDEGLAREYQSVR 2624
Cdd:TIGR02168  895 ELEEL-----SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL-----TLEEAEALENKIE 964

                          890
                   ....*....|....*....
gi 688616512  2625 LANKQLEREKAQLLRQIQR 2643
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 687-1403 1.82e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.46  E-value: 1.82e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   687 QVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSKSTGSsIPHKTLALPEEMTPTSAEaINALNEY 766
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE-LQKELYALANEISRLEQQ-KQILRER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   767 TVQLLQEIKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVdavkikeynh 846
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ---------- 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   847 lLETLEKDPSEIRREMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQAAVTERIgylqrfkemaa 926
Cdd:TIGR02168  381 -LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE----------- 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   927 fkMASLQKSLDVSVpaSELERANKQYTELTIKYRNLLQKDNHLVQKTTSLEHLETENMSLRERIdsinKELEISKEKLH- 1005
Cdd:TIGR02168  449 --LEELQEELERLE--EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV----KALLKNQSGLSg 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1006 ---------TLEQAFEN-ISTTGGE----IIMDKATKAVANSE------------IVSVSRRITTLEMKELNERQRAEHA 1059
Cdd:TIGR02168  521 ilgvlseliSVDEGYEAaIEAALGGrlqaVVVENLNAAKKAIAflkqnelgrvtfLPLDSIKGTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1060 QKMYEHLRNSLKQV-----------------------------EERNFELE----------TKFAELTKLNLEAQRIE-R 1099
Cdd:TIGR02168  601 LGVAKDLVKFDPKLrkalsyllggvlvvddldnalelakklrpGYRIVTLDgdlvrpggviTGGSAKTNSSILERRREiE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1100 ELRDELADSVSKhiSDADRKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDE 1179
Cdd:TIGR02168  681 ELEEKIEELEEK--IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1180 KA---------------LIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRAR 1244
Cdd:TIGR02168  759 LEaeieeleerleeaeeELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1245 HLRHTIQALRRQfsgalpLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEgkaQELELKLKGLEELIATLKDAkgA 1324
Cdd:TIGR02168  839 RLEDLEEQIEEL------SEDIESLAAEIEELEELIEELESELEALLNERASLE---EALALLRSELEELSEELREL--E 907

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616512  1325 QKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTisgLEEELVQQNNLLEERQLIWDQREVQLERQLDS 1403
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL---TLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 57-529 6.04e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 6.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    57 RMKLDEIKCAYEVVDsagaEQARIENELKAKVLkleSELEMAQRVMgggdKHFLRDEIRQLESHLERKEKEVTQLEKEMG 136
Cdd:pfam15921  291 RSQANSIQSQLEIIQ----EQARNQNSMYMRQL---SDLESTVSQL----RSELREAKRMYEDKIEELEKQLVLANSELT 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   137 KERKSNEELalrAEEAEEKNRKLKREIKQLTRKNEQLQQdiefyrkEAEQRESLQTKEESNEIQrrLTKANQQLYQCMEE 216
Cdd:pfam15921  360 EARTERDQF---SQESGNLDDQLQKLLADLHKREKELSL-------EKEQNKRLWDRDTGNSIT--IDHLRRELDDRNME 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   217 LQHAEDMAANLRSEnehLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRK--DRDHAKLQVRELTDQ----IQAR 290
Cdd:pfam15921  428 VQRLEALLKAMKSE---CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKvvEELTAKKMTLESSERtvsdLTAS 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   291 VEEDDPVMAAVNAKVEEWKSVLsgkDLEILEYQQMiRDLREKLRTAQMDSDksniiALQQAVQERDNQIKMLSEQVE--- 367
Cdd:pfam15921  505 LQEKERAIEATNAEITKLRSRV---DLKLQELQHL-KNEGDHLRNVQTECE-----ALKLQMAEKDKVIEILRQQIEnmt 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   368 QYTTEMERNAMLIEELKRPLKKDKghssdHQRRLEdlsaklqVAERKVLEAQRAAQLAERDARDKDKElndtLSRIRLYE 447
Cdd:pfam15921  576 QLVGQHGRTAGAMQVEKAQLEKEI-----NDRRLE-------LQEFKILKDKKDAKIRELEARVSDLE----LEKVKLVN 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   448 SGTDGLEaAISEIKECKNQirvrdreiegMIKEINQLEMKINNLLDENEDLRERLgLNPKEELDLSEFRRSKILKQRQYK 527
Cdd:pfam15921  640 AGSERLR-AVKDIKQERDQ----------LLNEVKTSRNELNSLSEDYEVLKRNF-RNKSEEMETTTNKLKMQLKSAQSE 707


                   ..
gi 688616512   528 AE 529
Cdd:pfam15921  708 LE 709
PTZ00121 PTZ00121
MAEBL; Provisional
 968-1828 4.51e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 4.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  968 HLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKA------TKAVANSEIVSVSRR 1041
Cdd:PTZ00121  993 HILQKPTCVIDKENHFSFTALTANTIDFNQNFNIEKIEELTEYGNNDDVLKEKDIIDEDidgnheGKAEAKAHVGQDEGL 1072

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1042 ITTLEMKELN--ERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSVSKHISDADRK 1119
Cdd:PTZ00121 1073 KPSYKDFDFDakEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAK 1152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1120 RITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALIAKLHQHivALQLSETT 1199
Cdd:PTZ00121 1153 RVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAED--AKKAEAVK 1230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1200 AISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQ---ALRRQFSGALPLAQQEKFSNTMLHL 1276
Cdd:PTZ00121 1231 KAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADElkkAEEKKKADEAKKAEEKKKADEAKKK 1310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1277 QEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLE-MRQSRELNTQREEI 1355
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEaKKKADAAKKKAEEK 1390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1356 KYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLPDPNQPLANQ 1435
Cdd:PTZ00121 1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1436 LDYALGKIKEHVRTILETKTTC----KILEEKLKEKEAALWSSEQNVLSRDKVINELRlrlpaAAEREKLLADLSKQEDS 1511
Cdd:PTZ00121 1471 KADEAKKKAEEAKKADEAKKKAeeakKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-----KAEEAKKADEAKKAEEK 1545

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1512 ESQPTLKVAHQtinnlqgrLDQKEEVLKKYQnllGKARQEQEEIAKRHEEEVRALHQKLDVYMDTSLDRFKQTALELIKK 1591
Cdd:PTZ00121 1546 KKADELKKAEE--------LKKAEEKKKAEE---AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK 1614

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1592 PTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLED-KHAAQMKGLSQEAE 1670
Cdd:PTZ00121 1615 AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEaKKAEEDEKKAAEAL 1694

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1671 ELRAQLIQMEKELHYLRTElEAQKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAA 1750
Cdd:PTZ00121 1695 KKEAEEAKKAEELKKKEAE-EKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1751 QKEEALNVQQIVDKQTKELRACV----RDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQnklQSEKEALE 1826
Cdd:PTZ00121 1774 RKEKEAVIEEELDEEDEKRRMEVdkkiKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQ---LEEADAFE 1850


                  ..
gi 688616512 1827 EH 1828
Cdd:PTZ00121 1851 KH 1852
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1344-1877 2.95e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.20  E-value: 2.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1344 QSRELNTQREEIK-YLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEAT 1422
Cdd:pfam15921  293 QANSIQSQLEIIQeQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQES 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1423 GSLPDPNQPLANQL--------------------DYALGKIKEHVRTILETKTT-CKILEEKLKEKEAALWSSEQNVLSR 1481
Cdd:pfam15921  373 GNLDDQLQKLLADLhkrekelslekeqnkrlwdrDTGNSITIDHLRRELDDRNMeVQRLEALLKAMKSECQGQMERQMAA 452

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1482 DKVINELRLR---LPAAAEREKLLADLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKAR-------QE 1551
Cdd:pfam15921  453 IQGKNESLEKvssLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRsrvdlklQE 532

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1552 QEEIaKRHEEEVRALHQKLDVYMDTSLDRFKQTALELIKKPTITVPTSKH-------LVRLAEMEQTVAEQDNSLsslsQ 1624
Cdd:pfam15921  533 LQHL-KNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHgrtagamQVEKAQLEKEINDRRLEL----Q 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1625 KLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQM---KGLSQEAEELRAQLIQMEKELHYLRTELEAQKEaNVRSP 1701
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR-NFRNK 686

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1702 SNTMKNLVERLKNQLALKEKQLKalskallelraeltsQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQ 1781
Cdd:pfam15921  687 SEEMETTTNKLKMQLKSAQSELE---------------QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQ 751

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1782 LAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKI 1861
Cdd:pfam15921  752 FLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQE 831

                          570       580
                   ....*....|....*....|.
gi 688616512  1862 R-----KLEHELDRKSISEPA 1877
Cdd:pfam15921  832 QesvrlKLQHTLDVKELQGPG 852
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
117-503 4.04e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 4.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  117 LESHLERKEkEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAE----QRESLQT 192
Cdd:PRK02224  243 LEEHEERRE-ELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEaveaRREELED 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  193 KEEsnEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKD 272
Cdd:PRK02224  322 RDE--ELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRER 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  273 RDHAKLQVRELTDQIQARVEEDDPVMAAVN-----------------AKVEEWKSVLSGKDLEILEYQQMIRDLREKLrt 335
Cdd:PRK02224  400 FGDAPVDLGNAEDFLEELREERDELREREAeleatlrtarerveeaeALLEAGKCPECGQPVEGSPHVETIEEDRERV-- 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  336 AQMDSDKSNIIALQQAVQERDNQIKMLSE---QVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAE 412
Cdd:PRK02224  478 EELEAELEDLEEEVEEVEERLERAEDLVEaedRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKR 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  413 RKVLEAQRAAQlaerDARDKDKELNDTLsrirlyesgtdgleAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLL 492
Cdd:PRK02224  558 EAAAEAEEEAE----EAREEVAELNSKL--------------AELKERIESLERIRTLLAAIADAEDEIERLREKREALA 619

                         410
                  ....*....|.
gi 688616512  493 DENEDLRERLG 503
Cdd:PRK02224  620 ELNDERRERLA 630
PTZ00121 PTZ00121
MAEBL; Provisional
 1758-2526 3.47e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 3.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1758 VQQIVDKQTKELRACVRDLNEElqlAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHlnelKKKIQ 1837
Cdd:PTZ00121 1029 IEELTEYGNNDDVLKEKDIIDE---DIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEA----FGKAE 1101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1838 RLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSisepadkrstlkEDKSSKEEVVRWEEGKkwqaRVDKMRNVLKEKE 1917
Cdd:PTZ00121 1102 EAKKTETGKAEEARKAEEAKKKAEDARKAEEARKA------------EDARKAEEARKAEDAK----RVEIARKAEDARK 1165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1918 REVDSQAKQLATMKELYSRLEQEKVSLQKKLKgrgvTADQVVGARTLEADKEIEELhkRNAELEQQIKVMKQQQALPRDA 1997
Cdd:PTZ00121 1166 AEEARKAEDAKKAEAARKAEEVRKAEELRKAE----DARKAEAARKAEEERKAEEA--RKAEDAKKAEAVKKAEEAKKDA 1239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1998 AMEDITNRNRYLEERLYSMESRLSKEPPSRPSDR--HSTSPSQLSWSSKVRSMTfDVIEAEQTQSSLLNSTVVVTEKEIS 2075
Cdd:PTZ00121 1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKaeEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKAD 1318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2076 VIEDKATQTSFRSidmgtAEVNQDDENVAKNKIDLEQKALMKDDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYA 2155
Cdd:PTZ00121 1319 EAKKKAEEAKKKA-----DAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2156 QEELKTNDEAEELESELTHREMMEKPLDEDQLEVEnEETNAEEMlystMNQAELETPKVLLEGDEDYGQEPEELLKcecd 2235
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE-EKKKADEA----KKKAEEAKKADEAKKKAEEAKKAEEAKK---- 1464

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2236 PSAESKELDEEETALSNSTTFDAKLVSEQPAMEKNKSFTPEAGFNPNLSEVSTSRELNANTENDilghlKAKVTRLNDKE 2315
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-----KAEEAKKADEA 1539

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2316 HSMKSKARKTSGRGSDTPSQREHEFQKENLRLSTENLELRFQLEQANKDLPrlKDQVSDLKEMCSVLKKEKAEVEKRLNH 2395
Cdd:PTZ00121 1540 KKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE--EARIEEVMKLYEEEKKMKAEEAKKAEE 1617

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2396 LRGSGRsgktipELEKTIGLMKKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKG---KQEEQLNSRLE 2472
Cdd:PTZ00121 1618 AKIKAE------ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAeeaKKAEEDEKKAA 1691

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....
gi 688616512 2473 SKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEETHQR 2526
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1962-2720 1.07e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1962 RTLEADKEIEELHKRNAELEQQIKVMKQQQALPRDAAMEDITNRNRYLEERLYSMESRLSKEPPSRPSDRHSTSPSQLSW 2041
Cdd:pfam02463  185 LAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2042 SSKVRSMTFDVIEAEQTQSSLLNSTVVVTEKEISVIE----DKATQTSFRSIDMGTAEVNQDDENVAKNKIDLEQKALMK 2117
Cdd:pfam02463  265 EKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllklERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2118 DDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELTHREMMEKpLDEDQLEVENEETNAE 2197
Cdd:pfam02463  345 KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEA-QLLLELARQLEDLLKE 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2198 EMLYSTMNQAELETPKVLLEGDEDYGQEPEELL---KCECDPSAESKELDEEETALSNSTTFDAKLVSEQPAMEKNKSFT 2274
Cdd:pfam02463  424 EKKEELEILEEEEESIELKQGKLTEEKEELEKQelkLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2275 P-EAGFNPNLSEVSTSRELNANTENDILGHLKAKVTRLNDKEHSMKSKARKTSGRGSDTPSQREHEFQKENLRLSTENLE 2353
Cdd:pfam02463  504 KaRSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLL 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2354 LRFQLEQANKDLP---------RLKDQVSDLKEMCSVLKKEKAEVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQ 2424
Cdd:pfam02463  584 IPKLKLPLKSIAVleidpilnlAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSE 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2425 RENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKGKQEEQLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRV 2504
Cdd:pfam02463  664 VKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQ 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2505 AKASLEVANEKLKAELEETHQRLLLAQSKGATLLGVDSKTWKSSVVTRLFENKMKGLESDIAKKNISISELKVQLKEANE 2584
Cdd:pfam02463  744 KIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLL 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2585 KLQATQHTVIQLKEQVELLKNVPVEATTDEGLAREYQSVRLANKQLEREKAQLLRQIQRNEVQLGTNKDGPGYTELQE-- 2662
Cdd:pfam02463  824 IEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEle 903

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 688616512  2663 ---QIKAANNEKKKLQDEVRKLTQELKHFDPTFFEELEDLKFNYNLEVKKNIVLEEQLKKL 2720
Cdd:pfam02463  904 eesQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2384-2503 3.43e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 46.00  E-value: 3.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2384 KEKAEVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQRENENLKRtsevnvqeQLATLERDHEKLKSEYEKLKGKQ 2463
Cdd:COG2433   386 IEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEA--------ELEEKDERIERLERELSEARSEE 457

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 688616512 2464 EEQLNSRLEsktkgIEKIMMENERLRKEIKKEAEAAEKLR 2503
Cdd:COG2433   458 RREIRKDRE-----ISRLDREIERLERELEEERERIEELK 492
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1201-1379 8.30e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 8.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1201 ISRLEATNTRLQKLEAQ--KLRDEQKLDEQQQALWHARQEGH---QRARHLRHTIQALRRQfsgalpLAQQEKFSNTMLH 1275
Cdd:COG4913   616 EAELAELEEELAEAEERleALEAELDALQERREALQRLAEYSwdeIDVASAEREIAELEAE------LERLDASSDDLAA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1276 LQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGA--QKVSEWHKKLEDVRLLEMRQSRELNTQRE 1353
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaeDLARLELRALLEERFAAALGDAVERELRE 769

                         170       180
                  ....*....|....*....|....*.
gi 688616512 1354 EikyLKNCVAEQERTISGLEEELVQQ 1379
Cdd:COG4913   770 N---LEERIDALRARLNRAEEELERA 792
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
988-1217 1.98e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  988 ERIDSINKELEISKEKLHTLEQAFEnisttggeiimdkatkavANSEIVSVSRRITTLEmkELNERQRAEHAQKMYEHLR 1067
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEPIRE------------------LAERYAAARERLAELE--YLRAALRLWFAQRRLELLE 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1068 NSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSvskhisdaDRKRITELEKTEANLRIEVSKLREVSDVAKM 1147
Cdd:COG4913   295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGN--------GGDRLEQLEREIERLERELEERERRRARLEA 366

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1148 QVSALDARQQSREKEVESLRRQVldyqaesdeKALIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQ 1217
Cdd:COG4913   367 LLAALGLPLPASAEEFAALRAEA---------AALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
 
Name Accession Description Interval E-value
CEP209_CC5 pfam16574
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ...
 1272-1399 1.28e-45

Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.


Pssm-ID: 465184 [Multi-domain]  Cd Length: 128  Bit Score: 161.40  E-value: 1.28e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1272 TMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQ 1351
Cdd:pfam16574    1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 688616512  1352 REEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLER 1399
Cdd:pfam16574   81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1118-1985 4.60e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.14  E-value: 4.60e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1118 RKRITE--LEKTEANLRievsklrEVSDVAKmqvsaldarqqSREKEVESLRRQVLDYQAESDEKALIAKLHQHIVALQL 1195
Cdd:TIGR02168  173 RRKETErkLERTRENLD-------RLEDILN-----------ELERQLKSLERQAEKAERYKELKAELRELELALLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1196 -SETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRrqfsgalplAQQEKFSNTML 1274
Cdd:TIGR02168  235 eELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA---------NEISRLEQQKQ 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1275 HLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQ--KVSEWHKKLEDVRLLEMRQSRELNTQR 1352
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeaELEELEAELEELESRLEELEEQLETLR 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1353 EEIKYLKNCVAEQERTISGLEEELVQqnnlLEERQLIWDQREVQLERQLDSYEKQ--QNEVLNTAQKFEEATGSLPDPNQ 1430
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLER----LEDRRERLQQEIEELLKKLEEAELKelQAELEELEEELEELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1431 planqldyALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLrlpAAAEREKLLADLSKQED 1510
Cdd:TIGR02168  462 --------ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK---NQSGLSGILGVLSELIS 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1511 SESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLgkarqEQEEIAKRHEEEVRALH----QKLDVYMDTSLDRFKQTAL 1586
Cdd:TIGR02168  531 VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFL-----KQNELGRVTFLPLDSIKgteiQGNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1587 ELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLE-----DKHAAQ 1661
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILErrreiEELEEK 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1662 MKGLSQEAEELRAQLIQMEKELHYLRTELEA--QKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTS 1739
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQlrKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1740 QAEQQIITNAAQKEEALNVQQivdkqtkelracvrdLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQ 1819
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEE---------------LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1820 SEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPAdkRSTLKEDKSSKEEVVRweeg 1899
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA--LALLRSELEELSEELR---- 904

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1900 kkwqarvdKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAE 1979
Cdd:TIGR02168  905 --------ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976


                   ....*.
gi 688616512  1980 LEQQIK 1985
Cdd:TIGR02168  977 LENKIK 982
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1053-1839 5.73e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 5.73e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1053 RQRAEHAQKMYEHLRNSLKQVEERNFELETKfaeLTKLNLEAQRIER--ELRDELaDSVSKHISDAD----RKRITELEK 1126
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLEDILNELERQ---LKSLERQAEKAERykELKAEL-RELELALLVLRleelREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1127 TEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAEsdekalIAKLHQHIVALQLSETTAISRLEA 1206
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE------ISRLEQQKQILRERLANLERQLEE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1207 TNTRLQKLEAQKLRDEQKLDEQQQALWHARQEgHQRARHLRHTIQALRRQFSGALPLAQQEkfsntMLHLQEDRARVRED 1286
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEE-LESLEAELEELEAELEELESRLEELEEQ-----LETLRSKVAQLELQ 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1287 AQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQE 1366
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1367 RTISGLEEELVQQNNLLEERQliwdqrevQLERQLDSYEKQQNEVLNTAQKFEEATGSLPD---PNQPLANQLDYALGKI 1443
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLE--------RLQENLEGFSEGVKALLKNQSGLSGILGVLSElisVDEGYEAAIEAALGGR 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1444 KEHVrtILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLPAAAEREKLLADLSKQEDSESQPTL------ 1517
Cdd:TIGR02168  547 LQAV--VVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALsyllgg 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1518 -KVAH--QTINNLQGRLDQKE------------------EVLKKYQNLLGKARQ--EQEEIAKRHEEEVRALHQKLDVY- 1573
Cdd:TIGR02168  625 vLVVDdlDNALELAKKLRPGYrivtldgdlvrpggvitgGSAKTNSSILERRREieELEEKIEELEEKIAELEKALAELr 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1574 --MDTSLDRFKQTALELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADM 1651
Cdd:TIGR02168  705 keLEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1652 ARLEdkhaAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKE--ANVRSPSNTMKNLVERLKNQLALKEKQLKALSKA 1729
Cdd:TIGR02168  785 EELE----AQIEQLKEELKALREALDELRAELTLLNEEAANLRErlESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1730 LLELRAELT-SQAEQQIITNA-AQKEEALNV----QQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLET 1803
Cdd:TIGR02168  861 IEELEELIEeLESELEALLNErASLEEALALlrseLEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 688616512  1804 LNK--------DLQRSQKSQNKLQSEKEALEEHLNELKKKIQRL 1839
Cdd:TIGR02168  941 LQErlseeyslTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1200-1870 1.81e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 1.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1200 AISRLEATNTRLQKLEAqkLRDEqkLDEQQQALwhARQeghqrARhlrhtiQALR-RQFSGALPLAQQEKFSNTMLHLQE 1278
Cdd:COG1196   177 AERKLEATEENLERLED--ILGE--LERQLEPL--ERQ-----AE------KAERyRELKEELKELEAELLLLKLRELEA 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1279 DRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDakgaqkvsEWHKKLEDVRLLEMRQSRELNTQREEikyl 1358
Cdd:COG1196   240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL--------ELEEAQAEEYELLAELARLEQDIARL---- 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1359 kncvAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLpdpnqplANQLDY 1438
Cdd:COG1196   308 ----EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA-------EAELAE 376

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1439 ALGKIKEHVRTILETKTTCKILEEKLKEKEAAlwssEQNVLSRDKVINELRLRLPAAAEREKLLADLSKQEDSESQPTLK 1518
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQLEELEEA----EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1519 VAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEvRALHQKLDVYMDTSLDRFKQTALELIKKPTITVPT 1598
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL-LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1599 SKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAmeHAADMARLEDKHAAQMKGLSQEAEELRAQLIQ 1678
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL--PLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1679 MEKELHYLRTELEAQKEANVRspsntmknlverlknQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNV 1758
Cdd:COG1196   610 EADARYYVLGDTLLGRTLVAA---------------RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL 674

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1759 QQIVDKQTKELRACVRDLNEElqlakdgvRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQR 1838
Cdd:COG1196   675 LEAEAELEELAERLAEEELEL--------EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746

                         650       660       670
                  ....*....|....*....|....*....|..
gi 688616512 1839 LSSGLQAQVESDGPTVDALQKKIRKLEHELDR 1870
Cdd:COG1196   747 LLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 87-869 1.01e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 1.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    87 KVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQL 166
Cdd:TIGR02168  214 RYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   167 TRKNEQLQQDIEFYRKEAEQ---------RESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKN 237
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANlerqleeleAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   238 LEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvmaAVNAKVEEWKSVLSGKDL 317
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK------LEEAELKELQAELEELEE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   318 EILEYQQMIRDLREKLRTAQMDSDKsniiaLQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDH 397
Cdd:TIGR02168  448 ELEELQEELERLEEALEELREELEE-----AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   398 QRRLEDLS--AKLQVAERKVLEAQRAAQLAE-----RDARDKDKElNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVR 470
Cdd:TIGR02168  523 GVLSELISvdEGYEAAIEAALGGRLQAVVVEnlnaaKKAIAFLKQ-NELGRVTFLPLDSIKGTEIQGNDREILKNIEGFL 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   471 DREIEgMIKEINQLEMKINNLLDE---NEDLRERLGLNPKEE-------LDLSEFRRSKILKQRQYKAENQVLLKEIERL 540
Cdd:TIGR02168  602 GVAKD-LVKFDPKLRKALSYLLGGvlvVDDLDNALELAKKLRpgyrivtLDGDLVRPGGVITGGSAKTNSSILERRREIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   541 EEERLELKQRIRALVKDKGVTVVSNSLLDNSVEEKPVRSLRPSSGSTDDEIKRKNERLQKELSNKEKELELRRSESTQFK 620
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   621 AKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGvSIPSLERLVNALEMKYSEgkfdaslhLRTQVDQLTGRNEELRQ 700
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE-ELKALREALDELRAELTL--------LNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   701 EMKTAREEAANTLSQLTKANEKIARLESEMESMskstgssiphktlalpEEMTPTSAEAINALNEYTVQLLQEIKNKGDS 780
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEEL----------------EELIEELESELEALLNERASLEEALALLRSE 895

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   781 IEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVDAVKIKEynhLLETLEKDPSEIRR 860
Cdd:TIGR02168  896 LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEA---LENKIEDDEEEARR 972


                   ....*....
gi 688616512   861 EMAETGRKI 869
Cdd:TIGR02168  973 RLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 110-698 1.55e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 1.55e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  110 LRDEIRQLESHLERKEKEVTQLEK----EMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAE 185
Cdd:COG1196   191 LEDILGELERQLEPLERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  186 QRES--LQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTD 263
Cdd:COG1196   271 ELRLelEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  264 AIMDQLRKDRDHAKLQVRELTDQIQARVEEDDpvmaAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQmdsdkS 343
Cdd:COG1196   351 EELEEAEAELAEAEEALLEAEAELAEAEEELE----ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE-----E 421

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  344 NIIALQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKV---LEAQR 420
Cdd:COG1196   422 ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLlllLEAEA 501

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  421 AAQLAERDARDKDKELNDTLSRIRLYESGTDGLE----AAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENE 496
Cdd:COG1196   502 DYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDK 581

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  497 DLRERLGLNPKEELDLSEFRRSKILKQRQYKAENQVLLKEIERLEEERLELKQRIRALVKDKGVTVVSnSLLDNSVEEKP 576
Cdd:COG1196   582 IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREV-TLEGEGGSAGG 660

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  577 VRSLRpsSGSTDDEIKRKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTG 656
Cdd:COG1196   661 SLTGG--SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|..
gi 688616512  657 VSIPSLERLVNALEMKYSEGKFDASlHLRTQVDQLTGRNEEL 698
Cdd:COG1196   739 EELLEEEELLEEEALEELPEPPDLE-ELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1649-2198 2.71e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.05  E-value: 2.71e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1649 ADMARLEDKHA---AQMKGLSQEAE------ELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKNLVERLKNQLALK 1719
Cdd:COG1196   186 ENLERLEDILGeleRQLEPLERQAEkaeryrELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAEL 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1720 EKQLKALSKALLELRAELTS--QAEQQIITNAAQKEEALNVQQI----VDKQTKELRACVRDLNEELQLAKDGVRAAKAR 1793
Cdd:COG1196   266 EAELEELRLELEELELELEEaqAEEYELLAELARLEQDIARLEErrreLEERLEELEEELAELEEELEELEEELEELEEE 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1794 ENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSI 1873
Cdd:COG1196   346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1874 SEPADKRSTLKEDKSSKEEVVRWEEGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGV 1953
Cdd:COG1196   426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1954 TADQVVGARTLEADKEIEElhkrnaELEQQIKVMKQQQALPRDAAMEDITNRNRYLEERLYSMESRLSKEPPSR------ 2027
Cdd:COG1196   506 FLEGVKAALLLAGLRGLAG------AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRatflpl 579

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2028 ----PSDRHSTSPSQLSWSSKVRSMTFDVIEAEQTQSSLLNSTVVVT------EKEISVIEDKATQTSFRSIDMGTAEVN 2097
Cdd:COG1196   580 dkirARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTlvaarlEAALRRAVTLAGRLREVTLEGEGGSAG 659

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2098 QDDENVAKNKIDLEQKALMKDDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELTHREM 2177
Cdd:COG1196   660 GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE 739

                         570       580
                  ....*....|....*....|.
gi 688616512 2178 MEKPLDEDQLEVENEETNAEE 2198
Cdd:COG1196   740 ELLEEEELLEEEALEELPEPP 760
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 400-1318 2.10e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 2.10e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   400 RLEDLSAKLqvaERKVLEAQRAAQLAERDardkdKELNDTLSRIRLYESGTDgLEAAISEIKECKNQIRVRDREIEGMIK 479
Cdd:TIGR02168  190 RLEDILNEL---ERQLKSLERQAEKAERY-----KELKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   480 EINQLEMKINNLLDENEDLRERLGLNPKEELDLSefrrskilkqrqykaenqvllkeierleeerlelkQRIRALVKDKG 559
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALA-----------------------------------NEISRLEQQKQ 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   560 VTVVSNSLLDNSVEEKPVRSlrpssgstdDEIKRKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKE 639
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQL---------EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   640 ilqaiqdtqkktptstgvsipsLERLVNALEMKYSEgkfdaslhLRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKA 719
Cdd:TIGR02168  377 ----------------------LEEQLETLRSKVAQ--------LELQIASLNNEIERLEARLERLEDRRERLQQEIEEL 426

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   720 NEKIARLESEMESMskstgssiphkTLALPEEMTPTSAEAINALNEYTVQLLQEIKNKGDSIEQLGSALEEYKRKFAVIR 799
Cdd:TIGR02168  427 LKKLEEAELKELQA-----------ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   800 HQQGLLYKEHQSERESWqKERDSFAELKSKLEEQREVDAvkikEYNHLLET-LEKDPSEIRREMAETGRKIVVLRVNEKC 878
Cdd:TIGR02168  496 RLQENLEGFSEGVKALL-KNQSGLSGILGVLSELISVDE----GYEAAIEAaLGGRLQAVVVENLNAAKKAIAFLKQNEL 570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   879 LTRrytTLLELEqhlRKENAKLKEDFTQMQAAVTERIGYLQRFKEMAAFKMASLQKSLDVSVPASELERANKQYTELTIK 958
Cdd:TIGR02168  571 GRV---TFLPLD---SIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPG 644

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   959 YRnLLQKDNHLV-----------QKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENIsttggeiimdKAT 1027
Cdd:TIGR02168  645 YR-IVTLDGDLVrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEEL----------EEE 713

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1028 KAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELEtkfAELTKLNLEAQRIERElRDELAD 1107
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE---ERLEEAEEELAEAEAE-IEELEA 789

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1108 SVSKHISDAD--RKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAE-SDEKALIA 1184
Cdd:TIGR02168  790 QIEQLKEELKalREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEiEELEELIE 869

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1185 KLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALwharqeghQRARHLRHTIQalrrqfsgalplA 1264
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRREL--------EELREKLAQLE------------L 929

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 688616512  1265 QQEKFSNTMLHLQEdraRVREDAQITEEE----RRKAEGKAQELELKLKGLEELIATL 1318
Cdd:TIGR02168  930 RLEGLEVRIDNLQE---RLSEEYSLTLEEaealENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 944-1561 2.71e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 2.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  944 ELERANKQYTELTIKYRNLLQKdnhLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAfenISTTGGEIIM 1023
Cdd:COG1196   240 ELEELEAELEELEAELEELEAE---LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQD---IARLEERRRE 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1024 DKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRD 1103
Cdd:COG1196   314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1104 ELAdsvskhisdADRKRITELEKTEANLRIEVSKLREvsdvakMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALI 1183
Cdd:COG1196   394 AAA---------ELAAQLEELEEAEEALLERLERLEE------ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1184 AKLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRRQFSGALPL 1263
Cdd:COG1196   459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1264 AQQEKFSNTMLHLQEDRARVREDAQitEEERRKAEGKAQELELklkgleeliATLKDAKGAQKVSEWHKKLEDVRLLEMR 1343
Cdd:COG1196   539 ALEAALAAALQNIVVEDDEVAAAAI--EYLKAAKAGRATFLPL---------DKIRARAALAAALARGAIGAAVDLVASD 607

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1344 QSRELNTQREEIKYLKNCVAEQERTISGLEeelvqqnnllEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATg 1423
Cdd:COG1196   608 LREADARYYVLGDTLLGRTLVAARLEAALR----------RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE- 676

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1424 slpdpnqpLANQLDYALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLPAAAEREKLLA 1503
Cdd:COG1196   677 --------AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 688616512 1504 DLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVlkkyqNLLgkARQEQEEIAKRHEE 1561
Cdd:COG1196   749 EEEALEELPEPPDLEELERELERLEREIEALGPV-----NLL--AIEEYEELEERYDF 799
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 781-1561 6.96e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.08  E-value: 6.96e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   781 IEQLGSALEEYKRKFAVIRHQ--QGLLYKEHQSERESWQK-----ERDSFAELKSKLEEQREVDAVKIKEYNHLLETLEK 853
Cdd:TIGR02168  188 LDRLEDILNELERQLKSLERQaeKAERYKELKAELRELELallvlRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   854 DPSEIRREMAETGRKIVVLrvnEKCLTRRYTTLLELEQHLRKENAKLKEDFTQmQAAVTERIGYLQRFKEMAAFKMASLQ 933
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEEL---QKELYALANEISRLEQQKQILRERLANLERQ-LEELEAQLEELESKLDELAEELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   934 KSLDVSvpASELERANKQYTELTIKYRNLLQKdnhLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFEN 1013
Cdd:TIGR02168  344 EKLEEL--KEELESLEAELEELEAELEELESR---LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1014 ISTTGGEiimdkATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLE 1093
Cdd:TIGR02168  419 LQQEIEE-----LLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1094 AQRIERELRDELADSV----SKHISDADRKRITELEKTEANLRIEVSK-LRE-----VSDVAKMQVSALDARQQSR---- 1159
Cdd:TIGR02168  494 LERLQENLEGFSEGVKallkNQSGLSGILGVLSELISVDEGYEAAIEAaLGGrlqavVVENLNAAKKAIAFLKQNElgrv 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1160 ---------EKEVESLRRQV-------------LDYQAESDEKALIAKLHQHIVALQLSETTAISRLE------------ 1205
Cdd:TIGR02168  574 tflpldsikGTEIQGNDREIlkniegflgvakdLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLrpgyrivtldgd 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1206 --------------------ATNTRLQKLEAQKLRDEQKLDEQQQAL---WHARQEGHQRARHLRHTIQALRRQFSGALP 1262
Cdd:TIGR02168  654 lvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELEKALaelRKELEELEEELEQLRKELEELSRQISALRK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1263 -----LAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKvsewhKKLEDV 1337
Cdd:TIGR02168  734 dlarlEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-----EALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1338 RLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLEErqliwdqrevqLERQLDSYEKQQNEVLNTAQK 1417
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES-----------LAAEIEELEELIEELESELEA 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1418 FEEATGSLPDPNQPLANQLDYALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNvlsrdkvINELRLRLpaaAE 1497
Cdd:TIGR02168  878 LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR-------IDNLQERL---SE 947

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 688616512  1498 REKLLADLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVlkkyqNLLgkARQEQEEIAKRHEE 1561
Cdd:TIGR02168  948 EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPV-----NLA--AIEEYEELKERYDF 1004
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1764-1998 7.29e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 63.63  E-value: 7.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1764 KQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGL 1843
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1844 QAQVESDGPTVDALQK--KIRKLEHELDRKSISEPADKRSTLKedksskeEVVRWEegkkwQARVDKMRNVLKEKEREVD 1921
Cdd:COG4942   100 EAQKEELAELLRALYRlgRQPPLALLLSPEDFLDAVRRLQYLK-------YLAPAR-----REQAEELRADLAELAALRA 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616512 1922 SQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEAdKEIEELHKRNAELEQQIKVMKQQQALPRDAA 1998
Cdd:COG4942   168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELA-AELAELQQEAEELEALIARLEAEAAAAAERT 243
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1118-1826 9.00e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 9.00e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1118 RKRITE--LEKTEANL-RIEVsKLREVsdvakmqvsaldarqqsrEKEVESLRRQV------LDYQAESDEKALIAKLHq 1188
Cdd:COG1196   173 RKEEAErkLEATEENLeRLED-ILGEL------------------ERQLEPLERQAekaeryRELKEELKELEAELLLL- 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1189 HIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRRqfsgalpLAQQEK 1268
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR-------LEQDIA 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1269 fsntmlHLQEDRARVREDAQITEEERRKAEGKAQELELKLkglEELIATLKDAKGAQKVSEwhKKLEDVRLLEMRQSREL 1348
Cdd:COG1196   306 ------RLEERRRELEERLEELEEELAELEEELEELEEEL---EELEEELEEAEEELEEAE--AELAEAEEALLEAEAEL 374

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1349 NTQREEIKylkncvAEQERTISGLEEELVQQNNLLEERQliwdqREVQLERQLDSYEKQQNEVLNTAQKFEEAtgslpdp 1428
Cdd:COG1196   375 AEAEEELE------ELAEELLEALRAAAELAAQLEELEE-----AEEALLERLERLEEELEELEEALAELEEE------- 436

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1429 nqplanqLDYALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVlsrdkviNELRLRLPAAAEREKLLADLSKQ 1508
Cdd:COG1196   437 -------EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL-------AELLEELAEAAARLLLLLEAEAD 502

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1509 EDSESQPTLKVAHQtinnlqgrldqkeevlkkyQNLLGKARQEQEEIAKRHEEEvRALHQKLDVYMDTSLDRFKQTALEL 1588
Cdd:COG1196   503 YEGFLEGVKAALLL-------------------AGLRGLAGAVAVLIGVEAAYE-AALEAALAAALQNIVVEDDEVAAAA 562

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1589 IKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQMKGLSQE 1668
Cdd:COG1196   563 IEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1669 AEELRAQLIQMEKELHYLRTELEAQKEANVRSpsntmknlvERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITN 1748
Cdd:COG1196   643 AGRLREVTLEGEGGSAGGSLTGGSRRELLAAL---------LEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 688616512 1749 AAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDGVRAAKAREnslkEDLETLNKDLQRsqksqnkLQSEKEALE 1826
Cdd:COG1196   714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP----PDLEELERELER-------LEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 807-1411 2.11e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.42  E-value: 2.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  807 KEHQSERESWQKERDSFAELKSKLEEQREVDAVKIKEYNHLLETLEKDPSEIRREMAETGRKIVVLRVNEKCLTRRYTTL 886
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  887 LELEQHLRKENAKLKEdftqmqaavterigylqrfkemaafkmaslqksldvsvpasELERANKQyteltikyrnLLQKD 966
Cdd:COG1196   301 EQDIARLEERRRELEE-----------------------------------------RLEELEEE----------LAELE 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  967 NHLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTtggEIIMDKATKAVANSEIVSVSRRITTLE 1046
Cdd:COG1196   330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE---ELEELAEELLEALRAAAELAAQLEELE 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1047 MKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSVSKHISDADRKRITELEK 1126
Cdd:COG1196   407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1127 TEANLRIEVSKLREVSDVAKMQV--SALDARQQSREKEVESLRRQVLDYQAESDEKALIAKLHQHIVALQLSETTAISRL 1204
Cdd:COG1196   487 AEAAARLLLLLEAEADYEGFLEGvkAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1205 EATN----TRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRRQFSGALPLAQQEKFSNTMLHLQEDR 1280
Cdd:COG1196   567 KAAKagraTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL 646

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1281 ARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEikylkn 1360
Cdd:COG1196   647 REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE------ 720

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 688616512 1361 cvAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEV 1411
Cdd:COG1196   721 --LEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1432-1987 2.68e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.03  E-value: 2.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1432 LANQLDYALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLpaaAEREKLLADLSKQEDS 1511
Cdd:COG1196   230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIAR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1512 ESQpTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVRALHQKLDvymdtSLDRFKQTALELIKK 1591
Cdd:COG1196   307 LEE-RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE-----ALLEAEAELAEAEEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1592 ptitvpTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQMKgLSQEAEE 1671
Cdd:COG1196   381 ------LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE-AAEEEAE 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1672 LRAQLIQMEKELHYLRTELE--AQKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNA 1749
Cdd:COG1196   454 LEEEEEALLELLAELLEEAAllEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1750 AQKEEALnvqqivdkQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHL 1829
Cdd:COG1196   534 AAYEAAL--------EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1830 NELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSIS------EPADKRSTLKEDKSSKEEVVRWEEGKKWQ 1903
Cdd:COG1196   606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTlegeggSAGGSLTGGSRRELLAALLEAEAELEELA 685

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1904 ARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQ----------VVGARTLEADKEIEEL 1973
Cdd:COG1196   686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEelleeeelleEEALEELPEPPDLEEL 765

                         570
                  ....*....|....
gi 688616512 1974 HKRNAELEQQIKVM 1987
Cdd:COG1196   766 ERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 35-646 3.12e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.65  E-value: 3.12e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   35 RDLKADDSEKMIQLFRISQTLLRMKLDEIKCAYEVVDSAGAEQARIENELKAKVLKLESELEMAQRvmgggDKHFLRDEI 114
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-----DIARLEERR 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  115 RQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEfyrkeAEQRESLQTKE 194
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA-----EAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  195 ESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRD 274
Cdd:COG1196   387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  275 HAKLQVRELTDQIQARVEEDDPVMAAVNAKVEewksvlsgkdlEILEYQQMIRDLREKLRTAQMDSDKSNIIALQQ--AV 352
Cdd:COG1196   467 ELLEEAALLEAALAELLEELAEAAARLLLLLE-----------AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGveAA 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  353 QERDNQIKMLSEQVEQYTTEMERNAMLIEELKRplkkdkghsSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDK 432
Cdd:COG1196   536 YEAALEAALAAALQNIVVEDDEVAAAAIEYLKA---------AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS 606

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  433 D-KELNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRERLGLNPKEELD 511
Cdd:COG1196   607 DlREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  512 LSEFRRSKILKQRQYKAENQVLLKEIERLEEERLELKQRIRALVKDKGVTVVSNSLLDNSVEEKPVRSLRPSSGSTdDEI 591
Cdd:COG1196   687 RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-EEL 765

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 688616512  592 KRKNERLQKELSNKEK-------ELElrrsestQFKAKLNEMLNENKQLEQGMKEILQAIQD 646
Cdd:COG1196   766 ERELERLEREIEALGPvnllaieEYE-------ELEERYDFLSEQREDLEEARETLEEAIEE 820
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 973-1679 4.72e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 4.72e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   973 TTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAfenISTTGGEIIMDKATKAVANSEIVSVSRRITTLEMKELNE 1052
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELTAELQELEEK---LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1053 RQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSVSKhiSDADRKRITELEKTEANLR 1132
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE--LEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1133 IEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALiAKLHQHIVALQLSETTAISRLEATNTRLQ 1212
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL-KELQAELEELEEELEELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1213 KLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRH---------TIQALRRQFSGALPLAQQ-----EKFSNTMLHLQE 1278
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDSLERLQENlegfsegvkALLKNQSGLSGILGVLSElisvdEGYEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1279 DRAR--VREDAQITEEE----RRKAEGKAQELELKLKG-------LEELIATLKDAKGAQK-----VSEWHKKLED---- 1336
Cdd:TIGR02168  545 GRLQavVVENLNAAKKAiaflKQNELGRVTFLPLDSIKgteiqgnDREILKNIEGFLGVAKdlvkfDPKLRKALSYllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1337 VRLLE-----MRQSRELN-------------------------------TQREEIKYLKNCVAEQERTISGLEEELVQQN 1380
Cdd:TIGR02168  625 VLVVDdldnaLELAKKLRpgyrivtldgdlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1381 NLLEERQliwdQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLPDPNQPLANQLDYALGKIKEHVRTILETKTTCKIL 1460
Cdd:TIGR02168  705 KELEELE----EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1461 EEKLKEKEAALWSSEQNVLSRDKVINELRLRLpaAAEREKLLADLSKQEDSESQptLKVAHQTINNLQGRLDQKEEVLKK 1540
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAEL--TLLNEEAANLRERLESLERR--IAATERRLEDLEEQIEELSEDIES 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1541 YQNLLGKARQEQEEIAKRHEEEVrALHQKLDVYMDTSLDRFKQTALELikkptitvptSKHLVRLAEMEQTVAEQDNSLS 1620
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALL-NERASLEEALALLRSELEELSEEL----------RELESKRSELRRELEELREKLA 925

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 688616512  1621 SLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQMKGLSQEAEELRAQLIQM 1679
Cdd:TIGR02168  926 QLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 75-368 5.00e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 5.00e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    75 AEQARIENELKAKVLKLESELEMAQRVMGGGDK--HFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEA 152
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKelEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   153 EEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQ-RESL--------QTKEESNEIQRRLTKANQQLYQCMEELQHAEDM 223
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlREALdelraeltLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   224 AANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvMAAVNA 303
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRE----LEELRE 922

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 688616512   304 KVEEWKSVLSGKDLEILEYQQMIRDLREklRTAQMDSDKSNIIALQQAVQERdnQIKMLSEQVEQ 368
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERLSEEYS--LTLEEAEALENKIEDDEEEARR--RLKRLENKIKE 983
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 112-460 6.32e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 6.32e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   112 DEIRQLESHLERKEKEVTQLEKEMGKERKSNEE-LALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESL 190
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQQLERLRREREKAERyQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   191 --QTKEESNEIQRRLTKANQQLYQCMEELQHA-EDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMD 267
Cdd:TIGR02169  260 isELEKRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   268 QLRKDRDHAKLQVRELTDQIQARVEEDDPVMA---AVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQMDSDKsn 344
Cdd:TIGR02169  340 ELEREIEEERKRRDKLTEEYAELKEELEDLRAeleEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQR-- 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   345 iiaLQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQL 424
Cdd:TIGR02169  418 ---LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE 494

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 688616512   425 AERDARDKDKELNDTLSRIRLYESGTDGLEAAISEI 460
Cdd:TIGR02169  495 AEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQL 530
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1291-1915 7.70e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 7.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1291 EEERRKAEgKAQELELKLKGLEeliatlkdakgaqkVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTIS 1370
Cdd:COG1196   206 ERQAEKAE-RYRELKEELKELE--------------AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1371 GLEEELVQQNNLLEERQliwdQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLpdpnqplANQLDYALGKIKEHVRTI 1450
Cdd:COG1196   271 ELRLELEELELELEEAQ----AEEYELLAELARLEQDIARLEERRRELEERLEEL-------EEELAELEEELEELEEEL 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1451 LETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLpaAAEREKLLADLSKQEDSESQptLKVAHQTINNLQGR 1530
Cdd:COG1196   340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL--EELAEELLEALRAAAELAAQ--LEELEEAEEALLER 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1531 LDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVRALHQKLDvymdtsldrfkqtalelikkptitvptskhlvRLAEMEQ 1610
Cdd:COG1196   416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE--------------------------------EEEALLE 463

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1611 TVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQMKGLSQEAEELRAQLIQMEKEL-HYLRTE 1689
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYeAALEAA 543

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1690 LEAQKEANVRSPSNTMKNLVERLKNQLA--------LKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQI 1761
Cdd:COG1196   544 LAAALQNIVVEDDEVAAAAIEYLKAAKAgratflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1762 VDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLE-TLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLS 1840
Cdd:COG1196   624 GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGgSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 688616512 1841 SGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPADKRSTLKEDKSSKEEVVRWEEGKKWQARVDKMRNVLKE 1915
Cdd:COG1196   704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1774-2643 8.58e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 8.58e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1774 RDLNEELQLAKdgVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVEsdgpT 1853
Cdd:TIGR02168  216 KELKAELRELE--LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK----E 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1854 VDALQKKIRKLEHELDRKSisepaDKRSTLKEDKSSKEEVvrweegkkwqarvdkmrnvLKEKEREVDSQAKQLATMKEL 1933
Cdd:TIGR02168  290 LYALANEISRLEQQKQILR-----ERLANLERQLEELEAQ-------------------LEELESKLDELAEELAELEEK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1934 YSRLEQEKVSLQKKLKgrgvtadqvvgartlEADKEIEELHKRNAELEQQIKVMKQQQALPRdAAMEDITNRNRYLEERL 2013
Cdd:TIGR02168  346 LEELKEELESLEAELE---------------ELEAELEELESRLEELEEQLETLRSKVAQLE-LQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2014 YSMESRLSKeppsrpsdrhstspsqlswsskvrsmtfdvieaeqtqssllnstvvvTEKEISVIEDKATQTSFRSIDMGT 2093
Cdd:TIGR02168  410 ERLEDRRER-----------------------------------------------LQQEIEELLKKLEEAELKELQAEL 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2094 AEVNQDDENVAKNKIDLEQKAlmkddktEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELT 2173
Cdd:TIGR02168  443 EELEEELEELQEELERLEEAL-------EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2174 HREMMEKPLDEDQLEVENE-ETNAEEMLYSTMNQaeletpkVLLEGDEDYGQEPEELLKCECDPSAESKELDEEETALSN 2252
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGyEAAIEAALGGRLQA-------VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQG 588

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2253 STTFDAKLVSEQPAMEKNKSFTP---EAGFNPNLSEVSTSREL-NANTENDILGHLKAKVTRLNDKEHSMKSKARKTSGR 2328
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDpklRKALSYLLGGVLVVDDLdNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKT 668

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2329 GSDTPSQR----------------EHEFQKENLRLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKR 2392
Cdd:TIGR02168  669 NSSILERRreieeleekieeleekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2393 LNHLRGsgrsgktipELEKTIGLMKKVVEKVQRENENLKRTSE--VNVQEQLATLERDHEKLKSEYEKLKGKQEE----- 2465
Cdd:TIGR02168  749 IAQLSK---------ELTELEAEIEELEERLEEAEEELAEAEAeiEELEAQIEQLKEELKALREALDELRAELTLlneea 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2466 -QLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEEthqrlLLAQSKGATLLGVDSKT 2544
Cdd:TIGR02168  820 aNLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-----LLNERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2545 WKSSVvtrlfENKMKGLESDIAKKNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNVpveatTDEGLAREYQSVR 2624
Cdd:TIGR02168  895 ELEEL-----SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL-----TLEEAEALENKIE 964

                          890
                   ....*....|....*....
gi 688616512  2625 LANKQLEREKAQLLRQIQR 2643
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 687-1403 1.82e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.46  E-value: 1.82e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   687 QVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSKSTGSsIPHKTLALPEEMTPTSAEaINALNEY 766
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE-LQKELYALANEISRLEQQ-KQILRER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   767 TVQLLQEIKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVdavkikeynh 846
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ---------- 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   847 lLETLEKDPSEIRREMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQAAVTERIgylqrfkemaa 926
Cdd:TIGR02168  381 -LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE----------- 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   927 fkMASLQKSLDVSVpaSELERANKQYTELTIKYRNLLQKDNHLVQKTTSLEHLETENMSLRERIdsinKELEISKEKLH- 1005
Cdd:TIGR02168  449 --LEELQEELERLE--EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV----KALLKNQSGLSg 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1006 ---------TLEQAFEN-ISTTGGE----IIMDKATKAVANSE------------IVSVSRRITTLEMKELNERQRAEHA 1059
Cdd:TIGR02168  521 ilgvlseliSVDEGYEAaIEAALGGrlqaVVVENLNAAKKAIAflkqnelgrvtfLPLDSIKGTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1060 QKMYEHLRNSLKQV-----------------------------EERNFELE----------TKFAELTKLNLEAQRIE-R 1099
Cdd:TIGR02168  601 LGVAKDLVKFDPKLrkalsyllggvlvvddldnalelakklrpGYRIVTLDgdlvrpggviTGGSAKTNSSILERRREiE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1100 ELRDELADSVSKhiSDADRKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDE 1179
Cdd:TIGR02168  681 ELEEKIEELEEK--IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1180 KA---------------LIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRAR 1244
Cdd:TIGR02168  759 LEaeieeleerleeaeeELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1245 HLRHTIQALRRQfsgalpLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEgkaQELELKLKGLEELIATLKDAkgA 1324
Cdd:TIGR02168  839 RLEDLEEQIEEL------SEDIESLAAEIEELEELIEELESELEALLNERASLE---EALALLRSELEELSEELREL--E 907

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616512  1325 QKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTisgLEEELVQQNNLLEERQLIWDQREVQLERQLDS 1403
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL---TLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 226-1094 3.02e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 3.02e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   226 NLRSENEHLQKnLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKdrdhakLQVRELTDQIQARVEEDDPVMAAVNAKV 305
Cdd:TIGR02168  180 KLERTRENLDR-LEDILNELERQLKSLERQAEKAERYKELKAELRE------LELALLVLRLEELREELEELQEELKEAE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   306 EEWKSV---LSGKDLEILEYQQMIRDLREKLRTAQmdsdkSNIIALQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEE 382
Cdd:TIGR02168  253 EELEELtaeLQELEEKLEELRLEVSELEEEIEELQ-----KELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   383 LKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDKDKElndtlsrirlyesgtdgLEAAISEIKE 462
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ-----------------LETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   463 CKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRERLGLNPKEELDLSEFRRSKILKQRQykAENQVLLKEIERLEE 542
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQ--EELERLEEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   543 ERLELKQRIRALvkdkgvtvvsnslldnsveekpvRSLRPSSGSTDDEIKRKNERLQKeLSNKEKELELRRSESTQFKAK 622
Cdd:TIGR02168  469 ELEEAEQALDAA-----------------------ERELAQLQARLDSLERLQENLEG-FSEGVKALLKNQSGLSGILGV 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   623 LNEMLNENKQLEQGMKEILQA-IQDTQKKTPTSTGVSIPSLER----LVNALEMKYSEGKFDASLHL--RTQVDQLTGRN 695
Cdd:TIGR02168  525 LSELISVDEGYEAAIEAALGGrLQAVVVENLNAAKKAIAFLKQnelgRVTFLPLDSIKGTEIQGNDReiLKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   696 EELRQEMKTAREEAANTLSQ------LTKANEKIARLESEMESMSKsTGSSIPHKTLalpeeMTPTSAEAINALNEYTvq 769
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLGGvlvvddLDNALELAKKLRPGYRIVTL-DGDLVRPGGV-----ITGGSAKTNSSILERR-- 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   770 llQEIKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREvdavKIKEYNHLLE 849
Cdd:TIGR02168  677 --REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA----EVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   850 TLEKDPSEIRREMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQAAVT---ERIGYLQRFKEMAA 926
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTllnEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   927 FKMASLQKSLDVSvpASELERANKQYTELTikyRNLLQKDNHLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHT 1006
Cdd:TIGR02168  831 RRIAATERRLEDL--EEQIEELSEDIESLA---AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1007 LEQAFENIsttggeiimdKATKAVANSEIVSVSRRITTLEMKELNERQR--------AEHAQKMYEHLRNSLKQVEERNF 1078
Cdd:TIGR02168  906 LESKRSEL----------RRELEELREKLAQLELRLEGLEVRIDNLQERlseeysltLEEAEALENKIEDDEEEARRRLK 975

                          890
                   ....*....|....*.
gi 688616512  1079 ELETKFAELTKLNLEA 1094
Cdd:TIGR02168  976 RLENKIKELGPVNLAA 991
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1448-2253 3.28e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 3.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1448 RTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLP---AAAEREKLLADLSKQEDSESqptLKVAHQTI 1524
Cdd:TIGR02168  158 RAIFEEAAGISKYKERRKETERKLERTRENLDRLEDILNELERQLKsleRQAEKAERYKELKAELRELE---LALLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1525 NNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEE---EVRALHQKLDVYmdtsldrfkQTALELIKKptitvptskh 1601
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEEL---------QKELYALAN---------- 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1602 lvRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQvtaaQAMEHAADMARLEDKHA---AQMKGLSQEAEELRAQLIQ 1678
Cdd:TIGR02168  296 --EISRLEQQKQILRERLANLERQLEELEAQLEELES----KLDELAEELAELEEKLEelkEELESLEAELEELEAELEE 369

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1679 MEKELHYLRTELEAQKEAnvrspSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQiitNAAQKEEALNV 1758
Cdd:TIGR02168  370 LESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL---EEAELKELQAE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1759 QQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKE---ALEEHLNELKKK 1835
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEgvkALLKNQSGLSGI 521

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1836 IQRLSSGLQAQVE------------SDGPTVDALQKKIRKLE----HELDRKSISE-----PADKRSTLKEDKSSKEEVV 1894
Cdd:TIGR02168  522 LGVLSELISVDEGyeaaieaalggrLQAVVVENLNAAKKAIAflkqNELGRVTFLPldsikGTEIQGNDREILKNIEGFL 601

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1895 RW-EEGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELysRLEQEKVSLQ-KKLKGRGVTADQVVGAR--TLEADKEI 1970
Cdd:TIGR02168  602 GVaKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKL--RPGYRIVTLDgDLVRPGGVITGGSAKTNssILERRREI 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1971 EELHKRNAELEQQIKVMKQQQALPRDAAmEDITNRNRYLEERLYSMESRLS--KEPPSRPSDRHSTSPSQLSWSSKVRSM 2048
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKEL-EELEEELEQLRKELEELSRQISalRKDLARLEAEVEQLEERIAQLSKELTE 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2049 TFDVIEAEQTQSSLLNSTVVVTEKEISVIEDKATQTS----------------FRSIDMGTAEVNQDDENVAKNKIDLEQ 2112
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKeelkalrealdelraeLTLLNEEAANLRERLESLERRIAATER 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2113 KALMKDDKTEQEESNKEK--GSVEKDEEQPDETQRGQDVAVFEYAQEEL---KTNDEAEELESELthREMMEKPLD-EDQ 2186
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESlaAEIEELEELIEELESELEALLNERASLEEalaLLRSELEELSEEL--RELESKRSElRRE 916

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616512  2187 LEVENEETNAEEMLYSTMNQAELETPKVLLegdEDYGQEPEELLKCECDPSAESKELDEEETALSNS 2253
Cdd:TIGR02168  917 LEELREKLAQLELRLEGLEVRIDNLQERLS---EEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1661-2496 5.07e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 5.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1661 QMKGLSQEAEE-LRAQLIQMEKElHYLRTELEAQKEANVRSPSNTMKNLvERLKNQLALKEKQLKALSKALLELRAELtS 1739
Cdd:TIGR02169  199 QLERLRREREKaERYQALLKEKR-EYEGYELLKEKEALERQKEAIERQL-ASLEEELEKLTEEISELEKRLEEIEQLL-E 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1740 QAEQQIitNAAQKEEALNVQQIVDKQTKELRACVR---DLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQN 1816
Cdd:TIGR02169  276 ELNKKI--KDLGEEEQLRVKEKIGELEAEIASLERsiaEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1817 KLQSEKEALEEHLNELKKKIQRLSSGLQAQVESdgptVDALQKKIRKLEHELDrkSISEPADKRSTLKEDKSS-----KE 1891
Cdd:TIGR02169  354 KLTEEYAELKEELEDLRAELEEVDKEFAETRDE----LKDYREKLEKLKREIN--ELKRELDRLQEELQRLSEeladlNA 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1892 EVVRWEEG-KKWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKG-----------RGVTADQVV 1959
Cdd:TIGR02169  428 AIAGIEAKiNELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKlqrelaeaeaqARASEERVR 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1960 GAR--TLEADKEIEELHKRNAELeqqIKVMKQQQALPRDAA--------MEDITNRNRYLEERLYSMESRLSKEPPSRPS 2029
Cdd:TIGR02169  508 GGRavEEVLKASIQGVHGTVAQL---GSVGERYATAIEVAAgnrlnnvvVEDDAVAKEAIELLKRRKAGRATFLPLNKMR 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2030 DRHStsPSQLSWSSKVRSMTFDVIEAEQTQSS----LLNSTVVVTEKEisviEDKATQTSFRSIDMGTAEVNQDDENVAK 2105
Cdd:TIGR02169  585 DERR--DLSILSEDGVIGFAVDLVEFDPKYEPafkyVFGDTLVVEDIE----AARRLMGKYRMVTLEGELFEKSGAMTGG 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2106 NKIDLEQKALMKDDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELTHREMMEKPLDED 2185
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER 738

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2186 QLEVENEETNAEEMLysTMNQAELET-PKVLLEGDEDYGQEPEELLKCECDPS--------AESKELDEEETALSNST-T 2255
Cdd:TIGR02169  739 LEELEEDLSSLEQEI--ENVKSELKElEARIEELEEDLHKLEEALNDLEARLShsripeiqAELSKLEEEVSRIEARLrE 816

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2256 FDAKLVSEQPAMEKNKSftpeagfnpnlsEVSTSRELNANTENDIlGHLKAKVTRLNDKEHSMKSKARKTSGRGSDTPSQ 2335
Cdd:TIGR02169  817 IEQKLNRLTLEKEYLEK------------EIQELQEQRIDLKEQI-KSIEKEIENLNGKKEELEEELEELEAALRDLESR 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2336 REHefqkenlrLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKRLNHLRGSGRSGKTIPELEKTIGL 2415
Cdd:TIGR02169  884 LGD--------LKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLED 955

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2416 MKKVVEKVQRENENLKRTSEVNVQEQLATLERdheklkseYEKLKGKQEeqlnsRLESKTKGIEKIMMENERLRKEIKKE 2495
Cdd:TIGR02169  956 VQAELQRVEEEIRALEPVNMLAIQEYEEVLKR--------LDELKEKRA-----KLEEERKAILERIEEYEKKKREVFME 1022


                   .
gi 688616512  2496 A 2496
Cdd:TIGR02169 1023 A 1023
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 180-793 5.65e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 5.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  180 YRKEAEQRESLQTKEESNEIQRRLTKANqqlyqcmEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAV 259
Cdd:COG1196   218 LKEELKELEAELLLLKLRELEAELEELE-------AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  260 QQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvmaavnakVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQmd 339
Cdd:COG1196   291 YELLAELARLEQDIARLEERRRELEERLEELEEE-----------LAELEEELEELEEELEELEEELEEAEEELEEAE-- 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  340 sdkSNIIALQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQ 419
Cdd:COG1196   358 ---AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  420 RAAQLAERDARDKDKELNDTLSRIrlyESGTDGLEAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLR 499
Cdd:COG1196   435 EEEEEEEEALEEAAEEEAELEEEE---EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  500 ERLGLNPKEELDLSEFRRSKILKQRQYKAENQVLLKEIERLEEERLELKQRIRALVKDKGVTVvsnSLLDNSVEEKPVRS 579
Cdd:COG1196   512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRA---TFLPLDKIRARAAL 588

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  580 LRPSSGSTDDEIKRKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGVSI 659
Cdd:COG1196   589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  660 PSLERLVNALEMKYSEGKFDASLHLRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMEsmskstgs 739
Cdd:COG1196   669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE-------- 740

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 688616512  740 siphktLALPEEMTPTSAEAINALNEYTVQLLQEIKNKGDSIEQLGS----ALEEYKR 793
Cdd:COG1196   741 ------LLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPvnllAIEEYEE 792
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 57-529 6.04e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 6.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    57 RMKLDEIKCAYEVVDsagaEQARIENELKAKVLkleSELEMAQRVMgggdKHFLRDEIRQLESHLERKEKEVTQLEKEMG 136
Cdd:pfam15921  291 RSQANSIQSQLEIIQ----EQARNQNSMYMRQL---SDLESTVSQL----RSELREAKRMYEDKIEELEKQLVLANSELT 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   137 KERKSNEELalrAEEAEEKNRKLKREIKQLTRKNEQLQQdiefyrkEAEQRESLQTKEESNEIQrrLTKANQQLYQCMEE 216
Cdd:pfam15921  360 EARTERDQF---SQESGNLDDQLQKLLADLHKREKELSL-------EKEQNKRLWDRDTGNSIT--IDHLRRELDDRNME 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   217 LQHAEDMAANLRSEnehLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRK--DRDHAKLQVRELTDQ----IQAR 290
Cdd:pfam15921  428 VQRLEALLKAMKSE---CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKvvEELTAKKMTLESSERtvsdLTAS 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   291 VEEDDPVMAAVNAKVEEWKSVLsgkDLEILEYQQMiRDLREKLRTAQMDSDksniiALQQAVQERDNQIKMLSEQVE--- 367
Cdd:pfam15921  505 LQEKERAIEATNAEITKLRSRV---DLKLQELQHL-KNEGDHLRNVQTECE-----ALKLQMAEKDKVIEILRQQIEnmt 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   368 QYTTEMERNAMLIEELKRPLKKDKghssdHQRRLEdlsaklqVAERKVLEAQRAAQLAERDARDKDKElndtLSRIRLYE 447
Cdd:pfam15921  576 QLVGQHGRTAGAMQVEKAQLEKEI-----NDRRLE-------LQEFKILKDKKDAKIRELEARVSDLE----LEKVKLVN 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   448 SGTDGLEaAISEIKECKNQirvrdreiegMIKEINQLEMKINNLLDENEDLRERLgLNPKEELDLSEFRRSKILKQRQYK 527
Cdd:pfam15921  640 AGSERLR-AVKDIKQERDQ----------LLNEVKTSRNELNSLSEDYEVLKRNF-RNKSEEMETTTNKLKMQLKSAQSE 707


                   ..
gi 688616512   528 AE 529
Cdd:pfam15921  708 LE 709
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1656-1884 1.56e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 1.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1656 DKHAAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKEAnvrspSNTMKNLVERLKNQLALKEKQLKALSKALLELRA 1735
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR-----IAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1736 ELTSQAEQ-----------------QIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLakdgVRAAKARENSLK 1798
Cdd:COG4942    98 ELEAQKEElaellralyrlgrqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE----LAALRAELEAER 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1799 EDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESdgptvdaLQKKIRKLEHELDRKSISEPAD 1878
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE-------LEALIARLEAEAAAAAERTPAA 246


                  ....*.
gi 688616512 1879 KRSTLK 1884
Cdd:COG4942   247 GFAALK 252
PTZ00121 PTZ00121
MAEBL; Provisional
 968-1828 4.51e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 4.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  968 HLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKA------TKAVANSEIVSVSRR 1041
Cdd:PTZ00121  993 HILQKPTCVIDKENHFSFTALTANTIDFNQNFNIEKIEELTEYGNNDDVLKEKDIIDEDidgnheGKAEAKAHVGQDEGL 1072

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1042 ITTLEMKELN--ERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSVSKHISDADRK 1119
Cdd:PTZ00121 1073 KPSYKDFDFDakEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAK 1152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1120 RITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALIAKLHQHivALQLSETT 1199
Cdd:PTZ00121 1153 RVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAED--AKKAEAVK 1230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1200 AISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQ---ALRRQFSGALPLAQQEKFSNTMLHL 1276
Cdd:PTZ00121 1231 KAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADElkkAEEKKKADEAKKAEEKKKADEAKKK 1310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1277 QEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLE-MRQSRELNTQREEI 1355
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEaKKKADAAKKKAEEK 1390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1356 KYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLPDPNQPLANQ 1435
Cdd:PTZ00121 1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1436 LDYALGKIKEHVRTILETKTTC----KILEEKLKEKEAALWSSEQNVLSRDKVINELRlrlpaAAEREKLLADLSKQEDS 1511
Cdd:PTZ00121 1471 KADEAKKKAEEAKKADEAKKKAeeakKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-----KAEEAKKADEAKKAEEK 1545

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1512 ESQPTLKVAHQtinnlqgrLDQKEEVLKKYQnllGKARQEQEEIAKRHEEEVRALHQKLDVYMDTSLDRFKQTALELIKK 1591
Cdd:PTZ00121 1546 KKADELKKAEE--------LKKAEEKKKAEE---AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK 1614

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1592 PTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLED-KHAAQMKGLSQEAE 1670
Cdd:PTZ00121 1615 AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEaKKAEEDEKKAAEAL 1694

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1671 ELRAQLIQMEKELHYLRTElEAQKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAA 1750
Cdd:PTZ00121 1695 KKEAEEAKKAEELKKKEAE-EKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1751 QKEEALNVQQIVDKQTKELRACV----RDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQnklQSEKEALE 1826
Cdd:PTZ00121 1774 RKEKEAVIEEELDEEDEKRRMEVdkkiKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQ---LEEADAFE 1850


                  ..
gi 688616512 1827 EH 1828
Cdd:PTZ00121 1851 KH 1852
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1718-1947 7.25e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 7.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1718 LKEKQLKALSKALLELRAELtSQAEQQIITnAAQKEEALnvQQIVDKQTKELRAcvRDLNEELQLAKDGVRAAKARE--N 1795
Cdd:COG4913   218 LEEPDTFEAADALVEHFDDL-ERAHEALED-AREQIELL--EPIRELAERYAAA--RERLAELEYLRAALRLWFAQRrlE 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1796 SLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQrlssglqaqvESDGPTVDALQKKIRKLEHELDRKsise 1875
Cdd:COG4913   292 LLEAELEELRAELARLEAELERLEARLDALREELDELEAQIR----------GNGGDRLEQLEREIERLERELEER---- 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1876 pADKRSTLKE--------DKSSKEEVvrWEEGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKK 1947
Cdd:COG4913   358 -ERRRARLEAllaalglpLPASAEEF--AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1604-1946 1.03e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.69  E-value: 1.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1604 RLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDkhaaqmkgLSQEAEELRAQLIQMEKEL 1683
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ--------LEQEEEKLKERLEELEEDL 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1684 HYLRTELEAQKEAnvrspsntmknlVERLKNQLALKEKQLKALSKALLELRAELtSQAEQQIITNAAQKEEALNVQQI-- 1761
Cdd:TIGR02169  747 SSLEQEIENVKSE------------LKELEARIEELEEDLHKLEEALNDLEARL-SHSRIPEIQAELSKLEEEVSRIEar 813

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1762 ---VDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQR 1838
Cdd:TIGR02169  814 lreIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1839 LSSGLQaqvesdgptvdALQKKIRKLEHELDRKS--ISEPADKRSTLKEDKSSKEEVVRW---------------EEGKK 1901
Cdd:TIGR02169  894 LEAQLR-----------ELERKIEELEAQIEKKRkrLSELKAKLEALEEELSEIEDPKGEdeeipeeelsledvqAELQR 962

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 688616512  1902 WQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQK 1946
Cdd:TIGR02169  963 VEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 77-381 1.72e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    77 QARIEnELKAKVLKLESELEMAQRVMgggdkHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKN 156
Cdd:TIGR02169  680 RERLE-GLKRELSSLQSELRRIENRL-----DELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEI 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   157 RKLKREIKQLTRKNEQLQQDIEFYRKEAE--------------QRESLQTKEESNEIQRRLTKANQQLYQCMEELQHAED 222
Cdd:TIGR02169  754 ENVKSELKELEARIEELEEDLHKLEEALNdlearlshsripeiQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   223 MAANLRSENEHLQ-------KNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELT---DQIQARVE 292
Cdd:TIGR02169  834 EIQELQEQRIDLKeqiksieKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELErkiEELEAQIE 913

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   293 EDDPVMAAVNAKVEEWKSVLS------GKDLEILEYQQMIRDLREKLRTAQMDSDKSNIIALqQAVQERDNQIKMLSEQV 366
Cdd:TIGR02169  914 KKRKRLSELKAKLEALEEELSeiedpkGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNM-LAIQEYEEVLKRLDELK 992

                          330
                   ....*....|....*
gi 688616512   367 EQYTTEMERNAMLIE 381
Cdd:TIGR02169  993 EKRAKLEEERKAILE 1007
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
61-502 2.10e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.77  E-value: 2.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   61 DEIKCAYEVVDSAGAEQARIE--NELKAKVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMgke 138
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAEL--- 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  139 rksnEELALRAEEAEEKNRKLKREIKQL-TRKNEQLQQDIEfyrkeaeqreslQTKEESNEIQRRLTKANQQLYQCMEEL 217
Cdd:COG4913   312 ----ERLEARLDALREELDELEAQIRGNgGDRLEQLEREIE------------RLERELEERERRRARLEALLAALGLPL 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  218 QHAEDMAANLRSENEHLQKNLEESVKEME----KMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQI--QARV 291
Cdd:COG4913   376 PASAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALaeALGL 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  292 EEDDPVMAA----VNAKVEEWKS----VLSGKDLEIL----EYQQMIR-----DLREKLRTAQMDSDKSNIIA------- 347
Cdd:COG4913   456 DEAELPFVGelieVRPEEERWRGaierVLGGFALTLLvppeHYAAALRwvnrlHLRGRLVYERVRTGLPDPERprldpds 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  348 ---------------LQQAVQERDNQIKMLS-EQVEQYTTEMERNAMLIEELKRPLKKDKGHS-------SDHQRRLEDL 404
Cdd:COG4913   536 lagkldfkphpfrawLEAELGRRFDYVCVDSpEELRRHPRAITRAGQVKGNGTRHEKDDRRRIrsryvlgFDNRAKLAAL 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  405 SAKLQVAERKVLEAQRAAQLAER-----------------------DARDKDKELNDTLSRIRLYESGTDGLEAAISEIK 461
Cdd:COG4913   616 EAELAELEEELAEAEERLEALEAeldalqerrealqrlaeyswdeiDVASAEREIAELEAELERLDASSDDLAALEEQLE 695

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|.
gi 688616512  462 ECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRERL 502
Cdd:COG4913   696 ELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRL 736
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2357-2685 2.61e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 2.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2357 QLEQANKDLPRLKDQVSDLKEMCSVLKKEkAEVEKRLNHLRGSGRsgktipELEKTIGLMKKVVEKVQRENenlkrtsev 2436
Cdd:TIGR02168  180 KLERTRENLDRLEDILNELERQLKSLERQ-AEKAERYKELKAELR------ELELALLVLRLEELREELEE--------- 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2437 nVQEQLATLERDHEKLKSEYEKLKGKQEEqLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKL 2516
Cdd:TIGR02168  244 -LQEELKEAEEELEELTAELQELEEKLEE-LRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2517 KAELEETHQRLLLAQSKGATLlgvdsktwksSVVTRLFENKMKGLESDIAKKNISISELKVQLKEANEKLQATQHTVIQL 2596
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAEL----------EEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2597 KEQVELLKNvpveatTDEGLAREYQSVRLANKQLEREKAQLLRQIQRN---EVQLGTNKDGPGYTELQEQIKAANNEKKK 2673
Cdd:TIGR02168  392 ELQIASLNN------EIERLEARLERLEDRRERLQQEIEELLKKLEEAelkELQAELEELEEELEELQEELERLEEALEE 465

                          330
                   ....*....|..
gi 688616512  2674 LQDEVRKLTQEL 2685
Cdd:TIGR02168  466 LREELEEAEQAL 477
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1344-1877 2.95e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.20  E-value: 2.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1344 QSRELNTQREEIK-YLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEAT 1422
Cdd:pfam15921  293 QANSIQSQLEIIQeQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQES 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1423 GSLPDPNQPLANQL--------------------DYALGKIKEHVRTILETKTT-CKILEEKLKEKEAALWSSEQNVLSR 1481
Cdd:pfam15921  373 GNLDDQLQKLLADLhkrekelslekeqnkrlwdrDTGNSITIDHLRRELDDRNMeVQRLEALLKAMKSECQGQMERQMAA 452

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1482 DKVINELRLR---LPAAAEREKLLADLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKAR-------QE 1551
Cdd:pfam15921  453 IQGKNESLEKvssLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRsrvdlklQE 532

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1552 QEEIaKRHEEEVRALHQKLDVYMDTSLDRFKQTALELIKKPTITVPTSKH-------LVRLAEMEQTVAEQDNSLsslsQ 1624
Cdd:pfam15921  533 LQHL-KNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHgrtagamQVEKAQLEKEINDRRLEL----Q 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1625 KLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQM---KGLSQEAEELRAQLIQMEKELHYLRTELEAQKEaNVRSP 1701
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR-NFRNK 686

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1702 SNTMKNLVERLKNQLALKEKQLKalskallelraeltsQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQ 1781
Cdd:pfam15921  687 SEEMETTTNKLKMQLKSAQSELE---------------QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQ 751

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1782 LAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKI 1861
Cdd:pfam15921  752 FLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQE 831

                          570       580
                   ....*....|....*....|.
gi 688616512  1862 R-----KLEHELDRKSISEPA 1877
Cdd:pfam15921  832 QesvrlKLQHTLDVKELQGPG 852
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
117-503 4.04e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 4.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  117 LESHLERKEkEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAE----QRESLQT 192
Cdd:PRK02224  243 LEEHEERRE-ELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEaveaRREELED 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  193 KEEsnEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKD 272
Cdd:PRK02224  322 RDE--ELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRER 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  273 RDHAKLQVRELTDQIQARVEEDDPVMAAVN-----------------AKVEEWKSVLSGKDLEILEYQQMIRDLREKLrt 335
Cdd:PRK02224  400 FGDAPVDLGNAEDFLEELREERDELREREAeleatlrtarerveeaeALLEAGKCPECGQPVEGSPHVETIEEDRERV-- 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  336 AQMDSDKSNIIALQQAVQERDNQIKMLSE---QVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAE 412
Cdd:PRK02224  478 EELEAELEDLEEEVEEVEERLERAEDLVEaedRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKR 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  413 RKVLEAQRAAQlaerDARDKDKELNDTLsrirlyesgtdgleAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLL 492
Cdd:PRK02224  558 EAAAEAEEEAE----EAREEVAELNSKL--------------AELKERIESLERIRTLLAAIADAEDEIERLREKREALA 619

                         410
                  ....*....|.
gi 688616512  493 DENEDLRERLG 503
Cdd:PRK02224  620 ELNDERRERLA 630
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 981-1979 4.20e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 52.74  E-value: 4.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   981 TENMSLRERIDSINKELEISKeKLHTLEQAFENISTTGGEIIMDKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQ 1060
Cdd:TIGR00606  166 SEGKALKQKFDEIFSATRYIK-ALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1061 KMYEHLRNSLKQVEE---RNFELETKFAELTKLNLEAQRIERELRDEL------ADSVSKHISDADRKRITELEKTEANL 1131
Cdd:TIGR00606  245 NELDPLKNRLKEIEHnlsKIMKLDNEIKALKSRKKQMEKDNSELELKMekvfqgTDEQLNDLYHNHQRTVREKERELVDC 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1132 RIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALIAKLHQHivalqlsETTAISRLEATNTRL 1211
Cdd:TIGR00606  325 QRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGF-------ERGPFSERQIKNFHT 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1212 QKLEaqklrdeqkldeqqqalwhaRQEGHQRarhlrhTIQALRRQFSGALPLAQQEkfsntmlhLQEDRARVREDAQITE 1291
Cdd:TIGR00606  398 LVIE--------------------RQEDEAK------TAAQLCADLQSKERLKQEQ--------ADEIRDEKKGLGRTIE 443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1292 EERRKAEGKAQELELKLKGLEELIATLKDAkgAQKVSEWHKKLEDVRLLEMRQSRElnTQREEIKYLKNCVAEQERTISG 1371
Cdd:TIGR00606  444 LKKEILEKKQEELKFVIKELQQLEGSSDRI--LELDQELRKAERELSKAEKNSLTE--TLKKEVKSLQNEKADLDRKLRK 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1372 LEEELVQQNNLLEERQliwdQREVQLERQLDSYEKQQNevlNTAQKFEEATGSLPD-PNQPLANQLDYALGKIKehvrti 1450
Cdd:TIGR00606  520 LDQEMEQLNHHTTTRT----QMEMLTKDKMDKDEQIRK---IKSRHSDELTSLLGYfPNKKQLEDWLHSKSKEI------ 586

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1451 letkttcKILEEKLKEKEAALWSSEQNvlsRDKVINELRLRLPAAAEREKLLADLSKQEDSESQ-PTLKVAHQTINNLQG 1529
Cdd:TIGR00606  587 -------NQTRDRLAKLNKELASLEQN---KNHINNELESKEEQLSSYEDKLFDVCGSQDEESDlERLKEEIEKSSKQRA 656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1530 RLDQKEEVLKKYQNLLGKARQEQEEIAKR---HEEEVRALHQKLDVYMDTSLDRFKQTALELIKKPTitvpTSKHLVRLA 1606
Cdd:TIGR00606  657 MLAGATAVYSQFITQLTDENQSCCPVCQRvfqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK----RRDEMLGLA 732

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1607 EMEQTVAE-QDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQ-----MKGLSQEAEELRAQLIQME 1680
Cdd:TIGR00606  733 PGRQSIIDlKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLtdvtiMERFQMELKDVERKIAQQA 812

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1681 KELHYLRTELEA----QKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAEltsqaEQQIITNAAQKeeal 1756
Cdd:TIGR00606  813 AKLQGSDLDRTVqqvnQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSE-----KLQIGTNLQRR---- 883

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1757 nvqQIVDKQTKELRACVRDLNEELQLAKDGVRA-AKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEE---HLNEL 1832
Cdd:TIGR00606  884 ---QQFEEQLVELSTEVQSLIREIKDAKEQDSPlETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNihgYMKDI 960

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1833 KKKIQRLSSGLQAQVESDGPTVDALQKkirklEHELDRKSISEpaDKRSTLKEDKSSKEEvvrwEEGKKWQARVDKMRNV 1912
Cdd:TIGR00606  961 ENKIQDGKDDYLKQKETELNTVNAQLE-----ECEKHQEKINE--DMRLMRQDIDTQKIQ----ERWLQDNLTLRKRENE 1029

                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 688616512  1913 LKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGR----GVTADQVVGARTLEADKEIEELHKRNAE 1979
Cdd:TIGR00606 1030 LKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRnhvlALGRQKGYEKEIKHFKKELREPQFRDAE 1100
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
56-254 5.63e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 5.63e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   56 LRMKLDEIKCAYEVVDSAGAEQARIENELKAkvlkLESELEMAQRVmggGDKHFLRDEIRQLESHLERKEKEVTQLEKEM 135
Cdd:COG4913   612 LAALEAELAELEEELAEAEERLEALEAELDA----LQERREALQRL---AEYSWDEIDVASAEREIAELEAELERLDASS 684

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  136 GKERKSNEELA---LRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRRLTKANQQlyq 212
Cdd:COG4913   685 DDLAALEEQLEeleAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD--- 761

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 688616512  213 cmeelQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNK 254
Cdd:COG4913   762 -----AVERELRENLEERIDALRARLNRAEEELERAMRAFNR 798
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 781-1561 6.25e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 6.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   781 IEQLGSALEEYKRKFAVIRhqqgLLYKEHQSERESWQKERDSFAELKSKLEEQREVDAvkiKEYNHLLETLEKDPSEIRR 860
Cdd:TIGR02169  172 KEKALEELEEVEENIERLD----LIIDEKRQQLERLRREREKAERYQALLKEKREYEG---YELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   861 EMAETGRKIVVLrvnEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQAAVTERIGYLQ----------RFKEMAAFKMA 930
Cdd:TIGR02169  245 QLASLEEELEKL---TEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEaeiaslersiAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   931 SLQKSLDVSVP---------ASELERANKQYTELTIKYRNLLQKDNHLVQKTTSLE----HLETENMSLRERIDSINKEL 997
Cdd:TIGR02169  322 ERLAKLEAEIDkllaeieelEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDkefaETRDELKDYREKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   998 EISKEKLHTLEQAFENISTTGGEIIMD----KATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQV 1073
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAiagiEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1074 EERNFELETKFAEL---TKLNLEAQRIERELRDELADSVS------KHISDADRKRITELEKTEANLRIEVskLREVSDV 1144
Cdd:TIGR02169  482 EKELSKLQRELAEAeaqARASEERVRGGRAVEEVLKASIQgvhgtvAQLGSVGERYATAIEVAAGNRLNNV--VVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1145 AKMQVSALDARQQSR------------EKEVESLRRQ-VLDYQ---AESDEKaliaklHQHIVALQLSETTAISRLEA-- 1206
Cdd:TIGR02169  560 AKEAIELLKRRKAGRatflplnkmrdeRRDLSILSEDgVIGFAvdlVEFDPK------YEPAFKYVFGDTLVVEDIEAar 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1207 ---------------------------------TNTRLQKLEAQKLRDE-QKLDEQQQALWHARQEGHQRARHLRHTIQA 1252
Cdd:TIGR02169  634 rlmgkyrmvtlegelfeksgamtggsraprggiLFSRSEPAELQRLRERlEGLKRELSSLQSELRRIENRLDELSQELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1253 LRRQFSGALplAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHK 1332
Cdd:TIGR02169  714 ASRKIGEIE--KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1333 KLEDVRllemRQSRELNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEvl 1412
Cdd:TIGR02169  792 RIPEIQ----AELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE-- 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1413 nTAQKFEEATGSLpdpnqplaNQLDYALGKIKehvRTILETKTTCKILEEKLKEKEAALWSSEQNvlsrdkvINELRLRL 1492
Cdd:TIGR02169  866 -LEEELEELEAAL--------RDLESRLGDLK---KERDELEAQLRELERKIEELEAQIEKKRKR-------LSELKAKL 926

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616512  1493 PAAAEREKLLADLSKQEDSESQPTLkvahqTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEE 1561
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPEEEL-----SLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDE 990
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1384-2030 6.27e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.89  E-value: 6.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1384 EERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLpdpNQPLANQLDYALGKIKEHVRTILETKTTCKILEEK 1463
Cdd:TIGR00618  164 EKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQL---LTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQ 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1464 LKEKEAALWSSEQNVLSRDKVINELRLRLPAAAEREKLLADLSKQEDSESQPTLKVAHQtinnlqgrlDQKEEVLKKYQN 1543
Cdd:TIGR00618  241 SHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHI---------KAVTQIEQQAQR 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1544 LLGKARQEQEEIAKRHEEEVRALHQKLDVYMDTSLDRFKQTALELIKKPTiTVPTS--KHLVRLAEMEQTVAEQDNSLSS 1621
Cdd:TIGR00618  312 IHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAH-EVATSirEISCQQHTLTQHIHTLQQQKTT 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1622 LSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDK-HAAQMKGLSQEAEELRAQLIQMEkelhylrTELEAQKEANVRS 1700
Cdd:TIGR00618  391 LTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLaHAKKQQELQQRYAELCAAAITCT-------AQCEKLEKIHLQE 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1701 PSNTMKNLVERLKN--QLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQIVdkqtkelRACVRDLNE 1778
Cdd:TIGR00618  464 SAQSLKEREQQLQTkeQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT-------RRMQRGEQT 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1779 ELQLAKDGvRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQ 1858
Cdd:TIGR00618  537 YAQLETSE-EDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQH 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1859 KKIRKLEHELDRKSIS--------EPADKRSTL--------KEDKSSKEEVVRWEEGKKWQARVDKM------------- 1909
Cdd:TIGR00618  616 ALLRKLQPEQDLQDVRlhlqqcsqELALKLTALhalqltltQERVREHALSIRVLPKELLASRQLALqkmqsekeqltyw 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1910 RNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAELEQQIKVMKQ 1989
Cdd:TIGR00618  696 KEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQ 775

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 688616512  1990 QQALPRDAAmEDITNRNRYLEERLYSMESRLSKEPPSRPSD 2030
Cdd:TIGR00618  776 TGAELSHLA-AEIQFFNRLREEDTHLLKTLEAEIGQEIPSD 815
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1608-1826 7.11e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.56  E-value: 7.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1608 MEQTVAEQDNSLSSLSQKLKIVTQELDQ-QRQVTAAQAMEHAADMARLEDKHAAQMKGLSQEAEELRAQLIQMEKELHYL 1686
Cdd:COG3206   166 LELRREEARKALEFLEEQLPELRKELEEaEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1687 RTELEAQKEANVRSPSNTmknLVERLKNQLALKEKQLKALSK-------ALLELRAELtSQAEQQIitnaaqKEEALNVQ 1759
Cdd:COG3206   246 RAQLGSGPDALPELLQSP---VIQQLRAQLAELEAELAELSArytpnhpDVIALRAQI-AALRAQL------QQEAQRIL 315

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616512 1760 QIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENslkeDLETLNKDLQRSQKSQNKLQSEKEALE 1826
Cdd:COG3206   316 ASLEAELEALQAREASLQAQLAQLEARLAELPELEA----ELRRLEREVEVARELYESLLQRLEEAR 378
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
126-735 7.56e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.60  E-value: 7.56e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  126 KEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESlqTKEESNEIQRRLTK 205
Cdd:PRK03918  172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE--LKEEIEELEKELES 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  206 ANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEEsVKEMEKMTDEYNKMKiavqqtdaimdQLRKDRDHAKLQVRELTD 285
Cdd:PRK03918  250 LEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE-LKELKEKAEEYIKLS-----------EFYEEYLDELREIEKRLS 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  286 QIQARVEEDDPVMAAVNAKVEEWKSvLSGKDLEILEYQQMIRDLREKLRTAQMDSDKSNIIALQQAVQERDNQIKMLsEQ 365
Cdd:PRK03918  318 RLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKEL-EE 395

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  366 VEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDKDkelndtlsrirl 445
Cdd:PRK03918  396 LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKR------------ 463

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  446 yesgtdgLEAAISEIKECKNQIRVRDREIEGMIKEINQLeMKINNLLDENEDLRERLGLNPKEELDlSEFRRSKILKQRQ 525
Cdd:PRK03918  464 -------IEKELKEIEEKERKLRKELRELEKVLKKESEL-IKLKELAEQLKELEEKLKKYNLEELE-KKAEEYEKLKEKL 534

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  526 YKAENQVllKEIERLEEERLELKQRIRALVKDKGvtvvsnslldnSVEEKPVRSLRPSSGSTDDEIKRKNERLQKELSNK 605
Cdd:PRK03918  535 IKLKGEI--KSLKKELEKLEELKKKLAELEKKLD-----------ELEEELAELLKELEELGFESVEELEERLKELEPFY 601

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  606 EKELELRRSEStqfkaKLNEMLNENKQLEQGMKEILQAIQDTQKKtptstgvsIPSLERLVNALEMKYSEGKFDASLHLR 685
Cdd:PRK03918  602 NEYLELKDAEK-----ELEREEKELKKLEEELDKAFEELAETEKR--------LEELRKELEELEKKYSEEEYEELREEY 668

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|
gi 688616512  686 TQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSK 735
Cdd:PRK03918  669 LELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEK 718
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 593-1215 8.75e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.66  E-value: 8.75e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   593 RKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGVSIPSLERLVNALEMK 672
Cdd:pfam15921  138 QSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRS 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   673 YSEGKFDASLHLRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANE-KIARLESEME---SMSKSTGSSIPHKTLAL 748
Cdd:pfam15921  218 LGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQdRIEQLISEHEveiTGLTEKASSARSQANSI 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   749 PEEMTPTSAEAINALNEYTVQLlqeiKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKS 828
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQL----SDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESG 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   829 KLEEQ----------REVDAVKIKEYNHLLETLEKDPS----EIRREMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLR 894
Cdd:pfam15921  374 NLDDQlqklladlhkREKELSLEKEQNKRLWDRDTGNSitidHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   895 KENAKLKEDFTQMQAAVTERIGYLQRFKEMAAFKMASLQKS----LDVSVPASELERA----NKQYTELTIKYRNLLQKD 966
Cdd:pfam15921  454 QGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSertvSDLTASLQEKERAieatNAEITKLRSRVDLKLQEL 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   967 NHLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKatkavANSEIVSVSRRITTLE 1046
Cdd:pfam15921  534 QHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEK-----AQLEKEINDRRLELQE 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1047 MKELNERQRAEhaqkmyehlrnsLKQVEERNFELETKFAELTKLNLEAQRIEREL---RDELADSVSKHISDADrKRITE 1123
Cdd:pfam15921  609 FKILKDKKDAK------------IRELEARVSDLELEKVKLVNAGSERLRAVKDIkqeRDQLLNEVKTSRNELN-SLSED 675

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1124 LEKTEANLRIEVSKLREVSDVAKMQVsaldarqQSREKEVESLRRQVLDYQAESDEKALIAklhqhiVALQLSETTAISR 1203
Cdd:pfam15921  676 YEVLKRNFRNKSEEMETTTNKLKMQL-------KSAQSELEQTRNTLKSMEGSDGHAMKVA------MGMQKQITAKRGQ 742

                          650
                   ....*....|..
gi 688616512  1204 LEATNTRLQKLE 1215
Cdd:pfam15921  743 IDALQSKIQFLE 754
PRK11281 PRK11281
mechanosensitive channel MscK;
1667-1831 9.74e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.45  E-value: 9.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1667 QEAEELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKNL-VERLKNQLALKEKQLKALSKALLELRAELTS---QAE 1742
Cdd:PRK11281   80 EETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLsLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSlqtQPE 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1743 --QQIITNAAQKEEALNVQQIVDKQTKE-LRACVRD-LNEELQL--AKDGVRAAKARENSLKEDLETLNKDLQRSQksQN 1816
Cdd:PRK11281  160 raQAALYANSQRLQQIRNLLKGGKVGGKaLRPSQRVlLQAEQALlnAQNDLQRKSLEGNTQLQDLLQKQRDYLTAR--IQ 237

                         170
                  ....*....|....*
gi 688616512 1817 KLQSEKEALEEHLNE 1831
Cdd:PRK11281  238 RLEHQLQLLQEAINS 252
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 75-281 1.06e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    75 AEQARIENELKAKvlKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEE 154
Cdd:TIGR02169  301 AEIASLERSIAEK--ERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDK 378

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   155 KNRKLKREIKQLTRKNEQLQQdiefyRKEAEQRESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHL 234
Cdd:TIGR02169  379 EFAETRDELKDYREKLEKLKR-----EINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ 453

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 688616512   235 QKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVR 281
Cdd:TIGR02169  454 EWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
57-195 1.59e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 50.63  E-value: 1.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   57 RMKLDEIKcaYEVVDSAGAEQArIEnELKAKVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMG 136
Cdd:COG2433   362 DVDRDEVK--ARVIRGLSIEEA-LE-ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELE 437

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 688616512  137 KERKSNEELALRAEEA-EEKNRKLK--REIKQLTRKNEQLQQDIEfyrKEAEQRESLQTKEE 195
Cdd:COG2433   438 EKDERIERLERELSEArSEERREIRkdREISRLDREIERLERELE---EERERIEELKRKLE 496
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 178-528 1.70e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 1.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   178 EFYRKEAEQRESLQTKEES-NEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEH----LQKNLEESVKEMEKMTDEY 252
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENiERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYegyeLLKEKEALERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   253 NKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDdpvMAAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREK 332
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEE---QLRVKEKIGELEAEIASLERSIAEKERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   333 LRTAQMDSDKsniialqqavqerdnqikmLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAE 412
Cdd:TIGR02169  324 LAKLEAEIDK-------------------LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   413 RKVLEAQRAAQLAERDARDKDKELNDTLSRIRLYESGTDGLEAAISEIKECKNQIrvrDREIEGMIKEINQLEMKINNLL 492
Cdd:TIGR02169  385 DELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINEL---EEEKEDKALEIKKQEWKLEQLA 461

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 688616512   493 DENEDLRERLgLNPKEELDLSEFRRSKilKQRQYKA 528
Cdd:TIGR02169  462 ADLSKYEQEL-YDLKEEYDRVEKELSK--LQRELAE 494
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 110-288 2.35e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  110 LRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQR-- 187
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELlr 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  188 -----------ESLQTKEESNEIQRRLT---KANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKmtdEYN 253
Cdd:COG4942   112 alyrlgrqpplALLLSPEDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE---ERA 188

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 688616512  254 KMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQ 288
Cdd:COG4942   189 ALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1118-1308 2.73e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 2.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1118 RKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQsrekevesLRRQVLDYQAESDEkalIAKLHQHIVALQlse 1197
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE--------ALQRLAEYSWDEID---VASAEREIAELE--- 674

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1198 tTAISRLEATNTRLQKLEAQ--KLRDE-QKLDEQQQALWHARQEGHQRARHLRHTIQALRRQFSGALPLAQQEKFSN--T 1272
Cdd:COG4913   675 -AELERLDASSDDLAALEEQleELEAElEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleE 753

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 688616512 1273 MLHLQEDRARVREDAQITEEERRKAEGKAQELELKL 1308
Cdd:COG4913   754 RFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
PTZ00121 PTZ00121
MAEBL; Provisional
 1758-2526 3.47e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 3.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1758 VQQIVDKQTKELRACVRDLNEElqlAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHlnelKKKIQ 1837
Cdd:PTZ00121 1029 IEELTEYGNNDDVLKEKDIIDE---DIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEA----FGKAE 1101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1838 RLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSisepadkrstlkEDKSSKEEVVRWEEGKkwqaRVDKMRNVLKEKE 1917
Cdd:PTZ00121 1102 EAKKTETGKAEEARKAEEAKKKAEDARKAEEARKA------------EDARKAEEARKAEDAK----RVEIARKAEDARK 1165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1918 REVDSQAKQLATMKELYSRLEQEKVSLQKKLKgrgvTADQVVGARTLEADKEIEELhkRNAELEQQIKVMKQQQALPRDA 1997
Cdd:PTZ00121 1166 AEEARKAEDAKKAEAARKAEEVRKAEELRKAE----DARKAEAARKAEEERKAEEA--RKAEDAKKAEAVKKAEEAKKDA 1239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1998 AMEDITNRNRYLEERLYSMESRLSKEPPSRPSDR--HSTSPSQLSWSSKVRSMTfDVIEAEQTQSSLLNSTVVVTEKEIS 2075
Cdd:PTZ00121 1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKaeEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKAD 1318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2076 VIEDKATQTSFRSidmgtAEVNQDDENVAKNKIDLEQKALMKDDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYA 2155
Cdd:PTZ00121 1319 EAKKKAEEAKKKA-----DAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2156 QEELKTNDEAEELESELTHREMMEKPLDEDQLEVEnEETNAEEMlystMNQAELETPKVLLEGDEDYGQEPEELLKcecd 2235
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE-EKKKADEA----KKKAEEAKKADEAKKKAEEAKKAEEAKK---- 1464

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2236 PSAESKELDEEETALSNSTTFDAKLVSEQPAMEKNKSFTPEAGFNPNLSEVSTSRELNANTENDilghlKAKVTRLNDKE 2315
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-----KAEEAKKADEA 1539

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2316 HSMKSKARKTSGRGSDTPSQREHEFQKENLRLSTENLELRFQLEQANKDLPrlKDQVSDLKEMCSVLKKEKAEVEKRLNH 2395
Cdd:PTZ00121 1540 KKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE--EARIEEVMKLYEEEKKMKAEEAKKAEE 1617

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2396 LRGSGRsgktipELEKTIGLMKKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKG---KQEEQLNSRLE 2472
Cdd:PTZ00121 1618 AKIKAE------ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAeeaKKAEEDEKKAA 1691

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....
gi 688616512 2473 SKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEETHQR 2526
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
110-496 3.66e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 3.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  110 LRDEIRQLESHLERKEKEVTQLEKEMGKERKsneelALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRES 189
Cdd:COG4717    93 LQEELEELEEELEELEAELEELREELEKLEK-----LLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEE 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  190 LQT--KEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMD 267
Cdd:COG4717   168 LEAelAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKE 247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  268 QLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQMDSDKSNIIA 347
Cdd:COG4717   248 ARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAA 327

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  348 LQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRplkkdkghsSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAER 427
Cdd:COG4717   328 LGLPPDLSPEELLELLDRIEELQELLREAEELEEELQL---------EELEQEIAALLAEAGVEDEEELRAALEQAEEYQ 398

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 688616512  428 DARDKDKELNDTLSRI---RLYESGTDGLEAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENE 496
Cdd:COG4717   399 ELKEELEELEEQLEELlgeLEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGE 470
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 77-236 3.90e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 49.26  E-value: 3.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    77 QARIEnELKAKVLKLESELEMaqrvmgggdkhfLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELalraEEAEEKN 156
Cdd:pfam05667  341 QEQLE-DLESSIQELEKEIKK------------LESSIKQVEEELEELKEQNEELEKQYKVKKKTLDLL----PDAEENI 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   157 RKLKREIKQLTRKNEQLQQDIEFYR----KEAEQRESLQTKEESnEIQRRLTKA---NQQLYQCMEELQHAEDMAANLRS 229
Cdd:pfam05667  404 AKLQALVDASAQRLVELAGQWEKHRvpliEEYRALKEAKSNKED-ESQRKLEEIkelREKIKEVAEEAKQKEELYKQLVA 482


                   ....*..
gi 688616512   230 ENEHLQK 236
Cdd:pfam05667  483 EYERLPK 489
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1750-2023 4.27e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.30  E-value: 4.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1750 AQKEEALNVQQIVDKQTKELRACVRDLNEELQ-LAKDGVRAAKARE-----------------NSLKEDLETLNKDLQRS 1811
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLErLRREREKAERYQAllkekreyegyellkekEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1812 QKSQNKLQSEK-------EALEEHLNELKKKIQRLSSGLQAQVESDGPTVDA----LQKKIRKLEHEL---DRKSISEPA 1877
Cdd:TIGR02169  250 EEELEKLTEEIselekrlEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAeiasLERSIAEKERELedaEERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1878 DKRSTLKEDKSSKEEVVRWE-EGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTAD 1956
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERkRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELD 409

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616512  1957 QVVgartleadKEIEELHKRNAELEQQIKVMKQQQAlPRDAAMEDITNRNRYLEERLYSMESRLSKE 2023
Cdd:TIGR02169  410 RLQ--------EELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWKLEQLAADLSKY 467
PTZ00121 PTZ00121
MAEBL; Provisional
 59-292 5.70e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.98  E-value: 5.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   59 KLDEIKCAYEVVDSAGAEQARIENELKAKVLKLESELEMaqrvmgggdkhflRDEIRQLESHLERKEKEVTQLEKEMGKE 138
Cdd:PTZ00121 1593 RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE-------------KKKVEQLKKKEAEEKKKAEELKKAEEEN 1659

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  139 RKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRRLTKANQQLYQCMEELQ 218
Cdd:PTZ00121 1660 KIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA 1739

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 688616512  219 HAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVqqtdaIMDQLRKDRDHAKLQVRELTDQIQARVE 292
Cdd:PTZ00121 1740 EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV-----IEEELDEEDEKRRMEVDKKIKDIFDNFA 1808
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 110-349 7.93e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 7.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  110 LRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRes 189
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ-- 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  190 lqtKEESNEIQRRLTKANQQLYqcMEELQHAEDMAANLRSenehlQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQL 269
Cdd:COG4942   103 ---KEELAELLRALYRLGRQPP--LALLLSPEDFLDAVRR-----LQYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  270 RKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQMDSDKSNIIALQ 349
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALK 252
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
110-501 8.42e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 8.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  110 LRDEIRQLESHLERKEKEVtqleKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRES 189
Cdd:PRK03918  212 ISSELPELREELEKLEKEV----KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  190 LQ---------------TKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRsENEHLQKNLEESVKEMEKMTDEYNK 254
Cdd:PRK03918  288 LKekaeeyiklsefyeeYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLE-ELKKKLKELEKRLEELEERHELYEE 366

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  255 MKIAVQQTDAIMDQLR-----------KDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSV-----LSGKDL- 317
Cdd:PRK03918  367 AKAKKEELERLKKRLTgltpeklekelEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpVCGRELt 446

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  318 --------------------EILEYQQMIRDLREKLRTAQMD-SDKSNIIALQQAVQerdnQIKMLSEQVEQYTTE-MER 375
Cdd:PRK03918  447 eehrkelleeytaelkriekELKEIEEKERKLRKELRELEKVlKKESELIKLKELAE----QLKELEEKLKKYNLEeLEK 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  376 NAMLIEELKRPLKKDKGHSS---DHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDKD----KELNDTLSRIRLYES 448
Cdd:PRK03918  523 KAEEYEKLKEKLIKLKGEIKslkKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfesvEELEERLKELEPFYN 602

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 688616512  449 GTDGLEAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRER 501
Cdd:PRK03918  603 EYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKK 655
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 1706-1866 8.95e-05

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 48.13  E-value: 8.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1706 KNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAqkEEALNVQQIVDKQTKELRACVRDLNEELQLAKD 1785
Cdd:pfam13166  320 ELDVEDIESEAEVLNSQLDGLRRALEAKRKDPFKSIELDSVDAKI--ESINDLVASINELIAKHNEITDNFEEEKNKAKK 397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1786 GVRAAkaRENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIqrlsSGLQAQVESDGPTVDALQKKIRKLE 1865
Cdd:pfam13166  398 KLRLH--LVEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKLREEI----KELEAQLRDHKPGADEINKLLKAFG 471


                   .
gi 688616512  1866 H 1866
Cdd:pfam13166  472 F 472
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1962-2720 1.07e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1962 RTLEADKEIEELHKRNAELEQQIKVMKQQQALPRDAAMEDITNRNRYLEERLYSMESRLSKEPPSRPSDRHSTSPSQLSW 2041
Cdd:pfam02463  185 LAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2042 SSKVRSMTFDVIEAEQTQSSLLNSTVVVTEKEISVIE----DKATQTSFRSIDMGTAEVNQDDENVAKNKIDLEQKALMK 2117
Cdd:pfam02463  265 EKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllklERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2118 DDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELTHREMMEKpLDEDQLEVENEETNAE 2197
Cdd:pfam02463  345 KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEA-QLLLELARQLEDLLKE 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2198 EMLYSTMNQAELETPKVLLEGDEDYGQEPEELL---KCECDPSAESKELDEEETALSNSTTFDAKLVSEQPAMEKNKSFT 2274
Cdd:pfam02463  424 EKKEELEILEEEEESIELKQGKLTEEKEELEKQelkLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2275 P-EAGFNPNLSEVSTSRELNANTENDILGHLKAKVTRLNDKEHSMKSKARKTSGRGSDTPSQREHEFQKENLRLSTENLE 2353
Cdd:pfam02463  504 KaRSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLL 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2354 LRFQLEQANKDLP---------RLKDQVSDLKEMCSVLKKEKAEVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQ 2424
Cdd:pfam02463  584 IPKLKLPLKSIAVleidpilnlAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSE 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2425 RENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKGKQEEQLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRV 2504
Cdd:pfam02463  664 VKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQ 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2505 AKASLEVANEKLKAELEETHQRLLLAQSKGATLLGVDSKTWKSSVVTRLFENKMKGLESDIAKKNISISELKVQLKEANE 2584
Cdd:pfam02463  744 KIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLL 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2585 KLQATQHTVIQLKEQVELLKNVPVEATTDEGLAREYQSVRLANKQLEREKAQLLRQIQRNEVQLGTNKDGPGYTELQE-- 2662
Cdd:pfam02463  824 IEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEle 903

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 688616512  2663 ---QIKAANNEKKKLQDEVRKLTQELKHFDPTFFEELEDLKFNYNLEVKKNIVLEEQLKKL 2720
Cdd:pfam02463  904 eesQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 145-368 1.41e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  145 LALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEfyrKEAEQRESLQtkEESNEIQRRLTKANQQLYQCMEELQHAEDMA 224
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELA---ALKKEEKALL--KQLAALERRIAALARRIRALEQELAALEAEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  225 ANLRSENEHLQKNLEESVKEMEKM------TDEYNKMKIAVQQTDAiMDQLRKDRDHAKL--QVRELTDQIQARVEEDDP 296
Cdd:COG4942    86 AELEKEIAELRAELEAQKEELAELlralyrLGRQPPLALLLSPEDF-LDAVRRLQYLKYLapARREQAEELRADLAELAA 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 688616512  297 VMAAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKLRT--AQMDSDKSNIIALQQAVQERDNQIKMLSEQVEQ 368
Cdd:COG4942   165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARleKELAELAAELAELQQEAEELEALIARLEAEAAA 238
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1619-2020 1.53e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 1.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1619 LSSLSQKLKIVTQELD--QQRQVTAAQAMEHAADMARLEDKHAAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKEA 1696
Cdd:PRK02224  208 LNGLESELAELDEEIEryEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRER 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1697 --NVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELtSQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVR 1774
Cdd:PRK02224  288 leELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRL-EECRVAAQAHNEEAESLREDADDLEERAEELREEAA 366

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1775 DLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQaqvesdgptv 1854
Cdd:PRK02224  367 ELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR---------- 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1855 dALQKKIRKLEHELDrksisepADKRSTLKEDKSSKEEVVRWEEGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELY 1934
Cdd:PRK02224  437 -TARERVEEAEALLE-------AGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1935 SRLEqekvslqkKLKGRGVTADQVVGAR--TLEADKE-IEELHKRNAELEQQIKVMKQQQALPRDAAmEDITNRNRYLEE 2011
Cdd:PRK02224  509 DRIE--------RLEERREDLEELIAERreTIEEKRErAEELRERAAELEAEAEEKREAAAEAEEEA-EEAREEVAELNS 579


                  ....*....
gi 688616512 2012 RLYSMESRL 2020
Cdd:PRK02224  580 KLAELKERI 588
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1491-1736 1.58e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1491 RLPAAAER-EKLLADLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEiakrHEEEVRALHQK 1569
Cdd:COG4913   256 PIRELAERyAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDA----LREELDELEAQ 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1570 LDvymDTSLDRfkqtaLELIKKptitvptskhlvRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAA 1649
Cdd:COG4913   332 IR---GNGGDR-----LEQLER------------EIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1650 DMARLEDKHAAqmkgLSQEAEELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKnLVERLKNQLALKEKQLKALSKa 1729
Cdd:COG4913   392 LLEALEEELEA----LEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLA-LRDALAEALGLDEAELPFVGE- 465


                  ....*..
gi 688616512 1730 LLELRAE 1736
Cdd:COG4913   466 LIEVRPE 472
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 947-1835 1.69e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 1.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   947 RANKQYTELTIKYRNLLQKDNHLVQKTTSLEHLETENMSLRERIDSINKELEiskEKLHTLEQAFENIS-TTGGEIIMDK 1025
Cdd:TIGR02169  217 LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLE---EIEQLLEELNKKIKdLGEEEQLRVK 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1026 ATKAVANSEIVSVSRRIttlEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQrierELRDEL 1105
Cdd:TIGR02169  294 EKIGELEAEIASLERSI---AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYA----ELKEEL 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1106 ADSVSkhisdadrkRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAE-SDEKALIA 1184
Cdd:TIGR02169  367 EDLRA---------ELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAiAGIEAKIN 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1185 KLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQrarhLRHTIQALRRQFSGALPLA 1264
Cdd:TIGR02169  438 ELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE----AEAQARASEERVRGGRAVE 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1265 QQEKFSNTMLH-LQEDRARVREDAQITEEERRKAEGKAQELELKLKGlEELIATLKDAKGAqkvsewhkKLEDVRLLEMR 1343
Cdd:TIGR02169  514 EVLKASIQGVHgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVA-KEAIELLKRRKAG--------RATFLPLNKMR 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1344 QS-RELNTQREE--IKYLKNCV---AEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLdsyekqqnevlntaqk 1417
Cdd:TIGR02169  585 DErRDLSILSEDgvIGFAVDLVefdPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEGEL---------------- 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1418 FEEATGSLPDPNQPLANQLDYALGKIKEhvrtiletkttcKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLPAAae 1497
Cdd:TIGR02169  649 FEKSGAMTGGSRAPRGGILFSRSEPAEL------------QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDA-- 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1498 reklladlsKQEDSESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVRALHQKldvymdts 1577
Cdd:TIGR02169  715 ---------SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL-------- 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1578 ldrfkQTALELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELD------QQRQVTAAQAMEHAADM 1651
Cdd:TIGR02169  778 -----EEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEylekeiQELQEQRIDLKEQIKSI 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1652 ARLEDKHAAQMKGLSQEAEELRAQLIQMEKELHYL---RTELEAQKEAnvrspsntMKNLVERLKNQLALKEKQLKALSK 1728
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESRLGDLkkeRDELEAQLRE--------LERKIEELEAQIEKKRKRLSELKA 924

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1729 ALLELRAELTsqaeqQIITNAAQKEEALNVQQIVDKQTKELRACVRDLneelqlakdgvRAAKARENSLKEDLETLNKDL 1808
Cdd:TIGR02169  925 KLEALEEELS-----EIEDPKGEDEEIPEEELSLEDVQAELQRVEEEI-----------RALEPVNMLAIQEYEEVLKRL 988

                          890       900
                   ....*....|....*....|....*..
gi 688616512  1809 QRSQKSQNKLQSEKEALEEHLNELKKK 1835
Cdd:TIGR02169  989 DELKEKRAKLEEERKAILERIEEYEKK 1015
PTZ00121 PTZ00121
MAEBL; Provisional
 59-508 1.71e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 1.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   59 KLDEIKCAYEVVDSAGAEQAriENELKAKVLKLESELEMAQRVMGGGDKHFLRDE----IRQLESHLERKEKEVTQLEKE 134
Cdd:PTZ00121 1523 KADEAKKAEEAKKADEAKKA--EEKKKADELKKAEELKKAEEKKKAEEAKKAEEDknmaLRKAEEAKKAEEARIEEVMKL 1600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  135 MGKERKSNEELALRAEEAEEKNRKLKREiKQLTRKNEQLQQDIEFYRKEAEQresLQTKEESNEIQR-RLTKANQQLYQC 213
Cdd:PTZ00121 1601 YEEEKKMKAEEAKKAEEAKIKAEELKKA-EEEKKKVEQLKKKEAEEKKKAEE---LKKAEEENKIKAaEEAKKAEEDKKK 1676

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  214 MEELQHAEDmaaNLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAvqqtdaimDQLRKDRDHAKLQVReltdqiQARVEE 293
Cdd:PTZ00121 1677 AEEAKKAEE---DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA--------EELKKAEEENKIKAE------EAKKEA 1739

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  294 DDPVMAAVNAKVEEwksvlsgkdleilEYQQMIRDLREKLRTAQMDSDKSNIIALQQAVQERDNQIKMlseQVEQYTTEM 373
Cdd:PTZ00121 1740 EEDKKKAEEAKKDE-------------EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRM---EVDKKIKDI 1803

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  374 ERNAMLIEELKR---PLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAErDARDKDKELNdtlsrirlYESGT 450
Cdd:PTZ00121 1804 FDNFANIIEGGKegnLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNE-NGEDGNKEAD--------FNKEK 1874

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 688616512  451 DGLEAAISEIKECKNQIRVRDREIEGMIKEiNQLEMKINNLLDENEDLRERLGLNPKE 508
Cdd:PTZ00121 1875 DLKEDDEEEIEEADEIEKIDKDDIEREIPN-NNMAGKNNDIIDDKLDKDEYIKRDAEE 1931
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1314-1558 1.75e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1314 LIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEELV---QQNNLLEERQLIW 1390
Cdd:COG4942     9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRaleQELAALEAELAEL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1391 DQREVQLERQLDSYEKQQNEVLNTAQKFEEATG-----SLPDPNQPLANQ--LDYALGKIKEHVRTILETKTTCKILEEK 1463
Cdd:COG4942    89 EKEIAELRAELEAQKEELAELLRALYRLGRQPPlalllSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAE 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1464 LKEKEAALWSSEQNVLSRDKVINELRlrlpaaAEREKLLADLSKQEDSESQptlkvahqtinnlqgRLDQKEEVLKKYQN 1543
Cdd:COG4942   169 LEAERAELEALLAELEEERAALEALK------AERQKLLARLEKELAELAA---------------ELAELQQEAEELEA 227

                         250
                  ....*....|....*
gi 688616512 1544 LLGKARQEQEEIAKR 1558
Cdd:COG4942   228 LIARLEAEAAAAAER 242
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1659-1882 1.81e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.75  E-value: 1.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1659 AAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKEAnvrspsntmknlVERLKNQLALKEKQLKALSKALLELRAELT 1738
Cdd:COG3883    22 QKELSELQAELEAAQAELDALQAELEELNEEYNELQAE------------LEALQAEIDKLQAEIAEAEAEIEERREELG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1739 SQAEQQ-----------IITNAAQKEEALN----VQQIVDKQTKELRAcVRDLNEELQLAKDGVRAAKARENSLKEDLET 1803
Cdd:COG3883    90 ERARALyrsggsvsyldVLLGSESFSDFLDrlsaLSKIADADADLLEE-LKADKAELEAKKAELEAKLAELEALKAELEA 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616512 1804 LNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPADKRST 1882
Cdd:COG3883   169 AKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAA 247
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
971-1394 1.96e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 1.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  971 QKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIImdkATKAVANSEIVSVSRRITTLEMKE- 1049
Cdd:PRK02224  248 ERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLL---AEAGLDDADAEAVEARREELEDRDe 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1050 ------LNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAEL------TKLNLEAQRIERELRDELADSVSKHISDAD 1117
Cdd:PRK02224  325 elrdrlEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELeseleeAREAVEDRREEIEELEEEIEELRERFGDAP 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1118 --------------------RKRITELEKTEANLRIEVSKLREVSDVAKM-----------QVSALDARQQSREK---EV 1163
Cdd:PRK02224  405 vdlgnaedfleelreerdelREREAELEATLRTARERVEEAEALLEAGKCpecgqpvegspHVETIEEDRERVEEleaEL 484

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1164 ESLRRQVLDYQAESDEKALIAKLHQHIVALQLSETTAISRLEATNTRL--QKLEAQKLRDE-QKLDEQQQALWHARQEGH 1240
Cdd:PRK02224  485 EDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIeeKRERAEELRERaAELEAEAEEKREAAAEAE 564

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1241 QRARHLRHTIQALRRQFSgalPLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKD 1320
Cdd:PRK02224  565 EEAEEAREEVAELNSKLA---ELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEA 641

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 688616512 1321 AKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNcvaeqerTISGLEEELVQQNNLLEERQLIWDQRE 1394
Cdd:PRK02224  642 EFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQA-------EIGAVENELEELEELRERREALENRVE 708
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1599-1830 2.21e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 2.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1599 SKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHA---AQMKGLSQEAEELRAQ 1675
Cdd:COG4913   231 VEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLElleAELEELRAELARLEAE 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1676 LIQMEKELHYLRTELEAQKEANVRSPSNTmknlVERLKNQLALKEKQLKALSKALLELrAELTSQAEQQIITNAAQKEEA 1755
Cdd:COG4913   311 LERLEARLDALREELDELEAQIRGNGGDR----LEQLEREIERLERELEERERRRARL-EALLAALGLPLPASAEEFAAL 385

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616512 1756 LnvqqivdkqtKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQN----KLQSEKEALEEHLN 1830
Cdd:COG4913   386 R----------AEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSnipaRLLALRDALAEALG 454
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1496-1718 3.20e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1496 AEREKLLADLSKQEDSeSQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVRALHQKLDVYMD 1575
Cdd:COG4942    37 AELEKELAALKKEEKA-LLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1576 TSldrfKQTALELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLE 1655
Cdd:COG4942   116 LG----RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALE 191

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 688616512 1656 ---DKHAAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKNLVERLKNQLAL 1718
Cdd:COG4942   192 alkAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKLPW 257
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1019-1839 3.23e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.50  E-value: 3.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1019 GEIIMDKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIE 1098
Cdd:pfam02463  163 AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1099 REL---RDELADSVSKHISDADRKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQA 1175
Cdd:pfam02463  243 QELlrdEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1176 ESDEKALIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARhlRHTIQALRR 1255
Cdd:pfam02463  323 KKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK--LKEEELELK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1256 QFSGALPLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQE----------LELKLKGLEELIATLKDAKGAQ 1325
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEekeelekqelKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1326 KVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLE-ERQLIWDQREVQLERQLDSY 1404
Cdd:pfam02463  481 KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEnYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1405 EKQQNEVLNTAQKFEEATGSLPDPNQPLANQLDYALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKV 1484
Cdd:pfam02463  561 EERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKES 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1485 INELRLRLPAAAEREKLLADLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVR 1564
Cdd:pfam02463  641 AKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1565 ALHQKLDVYMDTSLDRFKQTALELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQA 1644
Cdd:pfam02463  721 ELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1645 MEHAADMARLEDKHAAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKNLVERLKNQLALKEKQLK 1724
Cdd:pfam02463  801 EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1725 ALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETL 1804
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE 960

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 688616512  1805 NKDLQRSQKSQ-----NKLQSEKEALEEHLNELKKKIQRL 1839
Cdd:pfam02463  961 RNKRLLLAKEElgkvnLMAIEEFEEKEERYNKDELEKERL 1000
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2384-2503 3.43e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 46.00  E-value: 3.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2384 KEKAEVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQRENENLKRtsevnvqeQLATLERDHEKLKSEYEKLKGKQ 2463
Cdd:COG2433   386 IEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEA--------ELEEKDERIERLERELSEARSEE 457

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 688616512 2464 EEQLNSRLEsktkgIEKIMMENERLRKEIKKEAEAAEKLR 2503
Cdd:COG2433   458 RREIRKDRE-----ISRLDREIERLERELEEERERIEELK 492
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1639-1845 3.88e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 3.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1639 VTAAQAMEHAADMARLEDKHAAqmkgLSQEAEELRAQLIQMEKELHYLRTELEAQKEANVRSpsntmknLVERLKNQLAL 1718
Cdd:COG4913   245 EDAREQIELLEPIRELAERYAA----ARERLAELEYLRAALRLWFAQRRLELLEAELEELRA-------ELARLEAELER 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1719 KEKQLKALSKALLELRAELTS-------QAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELqlaKDGVRAAK 1791
Cdd:COG4913   314 LEARLDALREELDELEAQIRGnggdrleQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEF---AALRAEAA 390

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 688616512 1792 ARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQA 1845
Cdd:COG4913   391 ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLA 444
mukB PRK04863
chromosome partition protein MukB;
1128-1868 4.40e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.10  E-value: 4.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1128 EANLRIEVSKlrEVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQaesdeKALIAklhQHIVALQLSEttAISRLEAT 1207
Cdd:PRK04863  359 ELEERLEEQN--EVVEEADEQQEENEARAEAAEEEVDELKSQLADYQ-----QALDV---QQTRAIQYQQ--AVQALERA 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1208 NTRLQK--LEAQKLRD--EQKLDEQQQALWHARQEGHQRARHlrhtiQALRRQFSGALPLAQ-----------QEKFSNT 1272
Cdd:PRK04863  427 KQLCGLpdLTADNAEDwlEEFQAKEQEATEELLSLEQKLSVA-----QAAHSQFEQAYQLVRkiagevsrseaWDVAREL 501

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1273 MLHLQEDRARVREDAQIteeerrkaEGKAQELELKLKGLEELIATLKDAKGAQKVSewhkkLEDVRLLEMRQSrELNTQR 1352
Cdd:PRK04863  502 LRRLREQRHLAEQLQQL--------RMRLSELEQRLRQQQRAERLLAEFCKRLGKN-----LDDEDELEQLQE-ELEARL 567

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1353 EEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLER-------------QLDSYEKQQNEVLNTAQ--- 1416
Cdd:PRK04863  568 ESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARlreqsgeefedsqDVTEYMQQLLERERELTver 647

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1417 -KFEEATGSLPDPNQPLANQ---LDYALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVlsrdkVINELRLRL 1492
Cdd:PRK04863  648 dELAARKQALDEEIERLSQPggsEDPRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPARHAI-----VVPDLSDAA 722

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1493 PAAAEREKLLADLSKQEDS---------ESQPTLKVAHQTINNLQGRLDQKEEVlkkyqNLLGKA---------RQEQEE 1554
Cdd:PRK04863  723 EQLAGLEDCPEDLYLIEGDpdsfddsvfSVEELEKAVVVKIADRQWRYSRFPEV-----PLFGRAarekrieqlRAEREE 797

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1555 IAKRHEE------EVRALHQKLDVYMDTSLdrfkqtALELIKKPTitvptskhlVRLAEMEQTVAEQDNSLSSLSQKLKI 1628
Cdd:PRK04863  798 LAERYATlsfdvqKLQRLHQAFSRFIGSHL------AVAFEADPE---------AELRQLNRRRVELERALADHESQEQQ 862

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1629 VTQELDQQRQVTAAQAmEHAADMARLEDKHaaqmkgLSQEAEELRAQLIQMEKELHYLR------TELEAQKEANVRSPS 1702
Cdd:PRK04863  863 QRSQLEQAKEGLSALN-RLLPRLNLLADET------LADRVEEIREQLDEAEEAKRFVQqhgnalAQLEPIVSVLQSDPE 935

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1703 N--TMKNLVERLKNQLALKEKQLKALSKaLLELRAELTSQAEQQIITnaaqKEEALNVQqivdkqtkeLRACVRDLNEEL 1780
Cdd:PRK04863  936 QfeQLKQDYQQAQQTQRDAKQQAFALTE-VVQRRAHFSYEDAAEMLA----KNSDLNEK---------LRQRLEQAEQER 1001

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1781 QLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEAL--------EEHLNELKKKI-QRLS------SGLQA 1845
Cdd:PRK04863 1002 TRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLgvpadsgaEERARARRDELhARLSanrsrrNQLEK 1081

                         810       820
                  ....*....|....*....|...
gi 688616512 1846 QVESDGPTVDALQKKIRKLEHEL 1868
Cdd:PRK04863 1082 QLTFCEAEMDNLTKKLRKLERDY 1104
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
988-1388 4.92e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 4.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  988 ERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKM--YEH 1065
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPerLEE 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1066 LRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSVSKHISDAD--RKRITELEKTEANLRIEVSKLREVSD 1143
Cdd:COG4717   151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEelQQRLAELEEELEEAQEELEELEEELE 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1144 VAKMQVSALDARQQSREKEVESLRRQVL-----DYQAESDEKALIAKLHQHIVALQLSETTAISRLEATNT----RLQKL 1214
Cdd:COG4717   231 QLENELEAAALEERLKEARLLLLIAAALlallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGkeaeELQAL 310

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1215 EAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRRQFSGALPLAQQEKFSNTMLHLQEDRARVREDaqiTEEER 1294
Cdd:COG4717   311 PALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVE---DEEEL 387

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1295 RKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEE 1374
Cdd:COG4717   388 RAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEE 467

                         410
                  ....*....|....
gi 688616512 1375 ELVQQNNLLEERQL 1388
Cdd:COG4717   468 DGELAELLQELEEL 481
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
145-383 5.08e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 5.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  145 LALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRkeaEQRESLQTKEESNEIQRRLTKANQQLYQcmeelqhAEDMA 224
Cdd:COG3206   166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFR---QKNGLVDLSEEAKLLLQQLSELESQLAE-------ARAEL 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  225 ANLRSENEHLQKNLEESVKEmekmtdeynkmkIAVQQTDAIMDQLRKDRDHAKLQVRELtdqiQARVEEDDPVMAAVNAK 304
Cdd:COG3206   236 AEAEARLAALRAQLGSGPDA------------LPELLQSPVIQQLRAQLAELEAELAEL----SARYTPNHPDVIALRAQ 299

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616512  305 VEEWKSVLsgkdleileyQQMIRDLREKLRtAQMDSDKSNIIALQQAVQERDNQIKMLSEQVEQYtTEMERNAMLIEEL 383
Cdd:COG3206   300 IAALRAQL----------QQEAQRILASLE-AELEALQAREASLQAQLAQLEARLAELPELEAEL-RRLEREVEVAREL 366
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2414-2722 5.26e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 5.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2414 GLMKKVVEKVQRENENLKRTSEVnvQEQLATLERDHEKLKSEYEKLKGKQEEqLNSRLESKTKGIEKIMMENERLRKEIK 2493
Cdd:TIGR02169  692 SLQSELRRIENRLDELSQELSDA--SRKIGEIEKEIEQLEQEEEKLKERLEE-LEEDLSSLEQEIENVKSELKELEARIE 768

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2494 KEAEAAEKLRVAKASLEVAN--------EKLKAELEETHQRLllaqskGATLLGVDSKTWKSSVVTRLFENKMKGLESDI 2565
Cdd:TIGR02169  769 ELEEDLHKLEEALNDLEARLshsripeiQAELSKLEEEVSRI------EARLREIEQKLNRLTLEKEYLEKEIQELQEQR 842

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2566 AKKNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNvpveatTDEGLAREYQSVRLANKQLEREKAQLLRQIQRNE 2645
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES------RLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2646 VQLGTNKDGPGytELQEQIKAANNEKK-------------KLQDEVRKLTQELKHFDPTFF---EELEDLKFNYNLEVKK 2709
Cdd:TIGR02169  917 KRLSELKAKLE--ALEEELSEIEDPKGedeeipeeelsleDVQAELQRVEEEIRALEPVNMlaiQEYEEVLKRLDELKEK 994

                          330
                   ....*....|...
gi 688616512  2710 NIVLEEQLKKLSD 2722
Cdd:TIGR02169  995 RAKLEEERKAILE 1007
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 286-626 5.72e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 5.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   286 QIQARVEEDDPVMAAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQMDSDKsniiaLQQAVQERDNQIKMLSEQ 365
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEK-----LKERLEELEEDLSSLEQE 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   366 VEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQlaERDARDKDKELNDTLSRIRL 445
Cdd:TIGR02169  753 IENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRI--EARLREIEQKLNRLTLEKEY 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   446 YESGTDGLEaaiSEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRERLGLNPKEELDLSEFRRSKILKQRQ 525
Cdd:TIGR02169  831 LEKEIQELQ---EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE 907

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   526 YKAENQVLLKEIERLEEERLELKQRIRALVKDK--GVTVVSNSLLDNSVEEK------PVRSLRPSSGSTDDEIKRKNER 597
Cdd:TIGR02169  908 LEAQIEKKRKRLSELKAKLEALEEELSEIEDPKgeDEEIPEEELSLEDVQAElqrveeEIRALEPVNMLAIQEYEEVLKR 987

                          330       340
                   ....*....|....*....|....*....
gi 688616512   598 LqKELSNKEKELELRRSESTQFKAKLNEM 626
Cdd:TIGR02169  988 L-DELKEKRAKLEEERKAILERIEEYEKK 1015
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2353-2697 7.26e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 7.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2353 ELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQRENENLKR 2432
Cdd:PRK03918  263 ELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2433 TSE--VNVQEQLATLERDHEklksEYEKLKGKQEEQLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLE 2510
Cdd:PRK03918  343 LKKklKELEKRLEELEERHE----LYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK 418

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2511 VANEKLKAELEETHQRLLLAQSKGATLLGVDSKTWKSSvvtrlFENKMKGLESDIAKKNISISELKVQLKEAnEKLQATQ 2590
Cdd:PRK03918  419 KEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEE-----YTAELKRIEKELKEIEEKERKLRKELREL-EKVLKKE 492

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2591 HTVIQLKEQVELLKNVP-----VEATTDEGLAREYQSVRLANKQLEREKAQLLRQIQRNEvqlgtnkdgpgytELQEQIK 2665
Cdd:PRK03918  493 SELIKLKELAEQLKELEeklkkYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE-------------ELKKKLA 559

                         330       340       350
                  ....*....|....*....|....*....|..
gi 688616512 2666 AANNEKKKLQDEVRKLTQELKHFDPTFFEELE 2697
Cdd:PRK03918  560 ELEKKLDELEEELAELLKELEELGFESVEELE 591
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1715-1845 7.75e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 7.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1715 QLALKEKQLKALSKALLELRAELTS-QAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDGVRAAKAr 1793
Cdd:COG4913   611 KLAALEAELAELEEELAEAEERLEAlEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA- 689

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 688616512 1794 ensLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQA 1845
Cdd:COG4913   690 ---LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA 738
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 374-641 8.18e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.92  E-value: 8.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  374 ERNAMLIEELKRPLKKDkghssdhqrRLEDLSAKLQVAERKVleaqraAQLaeRDARDKDKELNDTLSRIRLyesgtDGL 453
Cdd:PRK05771   27 ELGVVHIEDLKEELSNE---------RLRKLRSLLTKLSEAL------DKL--RSYLPKLNPLREEKKKVSV-----KSL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  454 EAAISEIKECKNQIrvrDREIEGMIKEINQLEMKINNLLDENEDLrERLGlnpKEELDLSEFRRSKILKQ------RQYK 527
Cdd:PRK05771   85 EELIKDVEEELEKI---EKEIKELEEEISELENEIKELEQEIERL-EPWG---NFDLDLSLLLGFKYVSVfvgtvpEDKL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  528 AENQVLLKEIERLEEERLELKQRIRALVKDKGVTVVSNSLLDNSVEEKPVrslrPSSGSTDDEIkrknerlqkelSNKEK 607
Cdd:PRK05771  158 EELKLESDVENVEYISTDKGYVYVVVVVLKELSDEVEEELKKLGFERLEL----EEEGTPSELI-----------REIKE 222

                         250       260       270
                  ....*....|....*....|....*....|....
gi 688616512  608 ELELRRSESTQFKAKLNEMLNENKQLEQGMKEIL 641
Cdd:PRK05771  223 ELEEIEKERESLLEELKELAKKYLEELLALYEYL 256
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1201-1379 8.30e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 8.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1201 ISRLEATNTRLQKLEAQ--KLRDEQKLDEQQQALWHARQEGH---QRARHLRHTIQALRRQfsgalpLAQQEKFSNTMLH 1275
Cdd:COG4913   616 EAELAELEEELAEAEERleALEAELDALQERREALQRLAEYSwdeIDVASAEREIAELEAE------LERLDASSDDLAA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1276 LQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGA--QKVSEWHKKLEDVRLLEMRQSRELNTQRE 1353
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaeDLARLELRALLEERFAAALGDAVERELRE 769

                         170       180
                  ....*....|....*....|....*.
gi 688616512 1354 EikyLKNCVAEQERTISGLEEELVQQ 1379
Cdd:COG4913   770 N---LEERIDALRARLNRAEEELERA 792
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2335-2606 8.63e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 8.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2335 QREHEFQKENLRLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKRLNHLRgsgrsgKTIPELEKTIg 2414
Cdd:COG1196   246 AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLE------ERRRELEERL- 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2415 lmkkvvEKVQRENENLKRTSEvNVQEQLATLERDHEKLKSEYEKLKGKQEEQLNSRLESKTKGIEKImmenERLRKEIKK 2494
Cdd:COG1196   319 ------EELEEELAELEEELE-ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE----EELEELAEE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2495 EAEAAEKLRVAKASLEVANEKLKAELEETHQRLLLAQSKGATLLGVDSKTWKSSVVTRLFENKMKGLESDIAKKNISISE 2574
Cdd:COG1196   388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270
                  ....*....|....*....|....*....|..
gi 688616512 2575 LKVQLKEANEKLQATQHTVIQLKEQVELLKNV 2606
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLEA 499
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1123-1399 9.23e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 9.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1123 ELEKTEANLRIEVSKLREVSDvakmQVSALDARQQSREKEVESLRRQVLDYQAESDEkaliaklhQHIVALQLSEttAIS 1202
Cdd:COG3096   355 DLEELTERLEEQEEVVEEAAE----QLAEAEARLEAAEEEVDSLKSQLADYQQALDV--------QQTRAIQYQQ--AVQ 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1203 RLEatntrlqklEAQKLRDEQKLDEQQQALWHAR-----QEGHQRARHLRHTI---QALRRQFSGALPLAQQekfsntmL 1274
Cdd:COG3096   421 ALE---------KARALCGLPDLTPENAEDYLAAfrakeQQATEEVLELEQKLsvaDAARRQFEKAYELVCK-------I 484

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1275 HLQEDRARVREDAQITEEERRKAE---GKAQELELKLKGLEELIATLKDAKGAQKvsEWHKK----LEDVRLLEMRQSrE 1347
Cdd:COG3096   485 AGEVERSQAWQTARELLRRYRSQQalaQRLQQLRAQLAELEQRLRQQQNAERLLE--EFCQRigqqLDAAEELEELLA-E 561

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 688616512 1348 LNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLER 1399
Cdd:COG3096   562 LEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALER 613
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 84-754 1.02e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    84 LKAKVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKS----NEELALRAEEAEEKNRKL 159
Cdd:pfam15921  236 LKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQansiQSQLEIIQEQARNQNSMY 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   160 KREIKQLTRKNEQLQqdiefyrkeAEQRESLQTKEES-NEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNL 238
Cdd:pfam15921  316 MRQLSDLESTVSQLR---------SELREAKRMYEDKiEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADL 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   239 EESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvmaaVNAKVEEWKSVLSGKDLE 318
Cdd:pfam15921  387 HKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSE-------CQGQMERQMAAIQGKNES 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   319 ILEYQQMirdlreklrTAQMDSDKsniialqqavqerdnqiKMLSEQVEQYTTEmernAMLIEelkrplkkdkghssDHQ 398
Cdd:pfam15921  460 LEKVSSL---------TAQLESTK-----------------EMLRKVVEELTAK----KMTLE--------------SSE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   399 RRLEDLSAKLQVAERKVlEAQRAAQLAERDARD-KDKELNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVRDREIEGM 477
Cdd:pfam15921  496 RTVSDLTASLQEKERAI-EATNAEITKLRSRVDlKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENM 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   478 IKEINQLEMKINNLLDENEDLRERLGlnpKEELDLSEFRRSKILKQRQYKAENQVLLKEIERLEEERLELKQRIRALvkd 557
Cdd:pfam15921  575 TQLVGQHGRTAGAMQVEKAQLEKEIN---DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAV--- 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   558 KGVTVVSNSLLDnsvEEKPVRSLRPSSGSTDDEIKR--KNERLQKELSNKEKELELRRSEStqfkaKLNEMLNENKQLEQ 635
Cdd:pfam15921  649 KDIKQERDQLLN---EVKTSRNELNSLSEDYEVLKRnfRNKSEEMETTTNKLKMQLKSAQS-----ELEQTRNTLKSMEG 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   636 GMKEILQAIQDTQKKTPTSTGvSIPSLERLVNALE------------MKYSEGKFDASLH-LRTQVDQLTGRNEELRQEM 702
Cdd:pfam15921  721 SDGHAMKVAMGMQKQITAKRG-QIDALQSKIQFLEeamtnankekhfLKEEKNKLSQELStVATEKNKMAGELEVLRSQE 799

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 688616512   703 KTAREEAANTLSQLTKANEKIARLESEMESMSKSTGSSIPHKTLALPEEMTP 754
Cdd:pfam15921  800 RRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGP 851
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1680-2523 1.03e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.58  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1680 EKELHYLRTELEAQKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQ 1759
Cdd:pfam02463  185 LAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1760 QIVDKQTKELRACvrdlNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRL 1839
Cdd:pfam02463  265 EKLAQVLKENKEE----EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEEL 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1840 ssglQAQVESDGPTVDALQKKIRKLEHELDRKSISEPADKRSTLKEDKSSKEEVVRWEEGKKWQARVDKMRNVLKEKERE 1919
Cdd:pfam02463  341 ----EKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQ 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1920 VDSQAKQLATmKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAELEQQIKVMKQQQALPRDAAM 1999
Cdd:pfam02463  417 LEDLLKEEKK-EELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2000 EDITNRNRYLEERLYSMESRLSKEPPSRPSDRHSTSPSQLSWSSKVRSMTFDV---------IEAEQTQSSLLNSTVVVT 2070
Cdd:pfam02463  496 EERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAvivevsataDEVEERQKLVRALTELPL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2071 EKEISVIEDKATQTSFRSIDMGTAEVNQDDENVAKNKIDLEQKALMKDDKTEQEESNKEKGSVEKDEEQPDETQRGQDVA 2150
Cdd:pfam02463  576 GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2151 VFEYAQEELKTNDEAEELESELTHREMMEKPLDEDQLEVENEETNAEEMLYSTmnQAELETPKVLLEGDEDYGQEPEELL 2230
Cdd:pfam02463  656 EGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQRE--KEELKKLKLEAEELLADRVQEAQDK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2231 KCECDPSAESKELDEEETALSNSTTFDAKLVSEQPAMEKNKSFTPEAGFNPNLSEVSTSRELNANTENDILGHLKAKVTR 2310
Cdd:pfam02463  734 INEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEE 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2311 LNDKEHSMKSKARKTSGRGSDTPSQR---EHEFQKENLRLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKA 2387
Cdd:pfam02463  814 AELLEEEQLLIEQEEKIKEEELEELAlelKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE 893

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2388 EVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKGKQEEQL 2467
Cdd:pfam02463  894 KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 688616512  2468 NSRLESKTKGIEKimmENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEET 2523
Cdd:pfam02463  974 KVNLMAIEEFEEK---EERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELF 1026
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 126-908 1.05e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.58  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   126 KEVTQLEKEMGKERKSNEELALRAEE---AEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRR 202
Cdd:pfam02463  142 GKIEIIAMMKPERRLEIEEEAAGSRLkrkKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   203 LTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRE 282
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   283 LTDQIQARVEEDDPVMAAVNAKVEEWKSVLsgKDLEILEYQQMIRDLREKLRTAQMDSDKSNIIALQQAVQERDNQIKML 362
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELK--KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKK 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   363 SEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDKDKELNDTLSR 442
Cdd:pfam02463  380 KLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELK 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   443 IRLYESGTDGLEAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRERLGLNPKEELDLSEFRRSKILK 522
Cdd:pfam02463  460 LLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVE 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   523 QRQYKAENQVLLKEIERLEEERLELKQRIRALVKDKGVTVVSnslLDNSVEEKPVRSLRPSSGSTDDEIKRKNERLQKEL 602
Cdd:pfam02463  540 NYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLR---LLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEAD 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   603 SNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGVSIPSLERLVNALEMKYSEGKFDASL 682
Cdd:pfam02463  617 EDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   683 HLRTQVDQLTGRNEELRQEMKTARE-EAANTLSQLTKANEKIARLESEMESMSKSTGSSIPHKTLALPEEMTPTSAEAIN 761
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEElLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   762 ALNE-YTVQLLQEIKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVDAVK 840
Cdd:pfam02463  777 AEEReKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEEL 856

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 688616512   841 IKEYNHLLETLEKDPSEIRREMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQ 908
Cdd:pfam02463  857 ERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIK 924
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
110-503 1.15e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  110 LRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRES 189
Cdd:COG4717    51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPL 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  190 LQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEE--------SVKEMEKMTDEYNKMKIAVQQ 261
Cdd:COG4717   131 YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEElleqlslaTEEELQDLAEELEELQQRLAE 210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  262 TDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGKDLEILEYQQMIRD---LREKLRTAQM 338
Cdd:COG4717   211 LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlfLVLGLLALLF 290

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  339 DSDKSNIIALQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEA 418
Cdd:COG4717   291 LLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQ 370

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  419 QRAAQLAERDARDKDkELNDTLSRIRLYESGTDGLEAAISEIKECKNQIR--VRDREIEGMIKEINQLEMKINNLLDENE 496
Cdd:COG4717   371 EIAALLAEAGVEDEE-ELRAALEQAEEYQELKEELEELEEQLEELLGELEelLEALDEEELEEELEELEEELEELEEELE 449


                  ....*..
gi 688616512  497 DLRERLG 503
Cdd:COG4717   450 ELREELA 456
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1143-1920 1.20e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.44  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1143 DVAKMQVSALDARQQSREKEVESlRRQVLDYQAESDEKALIAKLHQHIVALQlsetTAISRLEATNTRLQKLEAQKLRDE 1222
Cdd:pfam12128  197 DVKSMIVAILEDDGVVPPKSRLN-RQQVEHWIRDIQAIAGIMKIRPEFTKLQ----QEFNTLESAELRLSHLHFGYKSDE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1223 QKLDEQQQALWHARQEGHQRARHLRHTIQALRRQFSGALPlAQQEKFSNTMLHLQ--EDRARVREDAQIteeERRKAEGK 1300
Cdd:pfam12128  272 TLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELS-AADAAVAKDRSELEalEDQHGAFLDADI---ETAAADQE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1301 -----AQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEE 1375
Cdd:pfam12128  348 qlpswQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQ 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1376 LVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLPDPNQPLANQL-------------DYALGK 1442
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVErlqselrqarkrrDQASEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1443 IKEHVRTILETKTTCKILEEKLK----------EKEAALWSSeqnvlSRDKVIN-ELRLRLPAAAErekLLADLSKQEDS 1511
Cdd:pfam12128  508 LRQASRRLEERQSALDELELQLFpqagtllhflRKEAPDWEQ-----SIGKVISpELLHRTDLDPE---VWDGSVGGELN 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1512 ESQPTLKVAHQTINNLQgrldQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVRALHQKLD---VYMDTSLDRFKQTALEL 1588
Cdd:pfam12128  580 LYGVKLDLKRIDVPEWA----ASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEkasREETFARTALKNARLDL 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1589 IKKPTITVPTSKHLVRLAEMEQTVAEQdnSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAadMARLEDKHAAQmkglsqe 1668
Cdd:pfam12128  656 RRLFDEKQSEKDKKNKALAERKDSANE--RLNSLEAQLKQLDKKHQAWLEEQKEQKREAR--TEKQAYWQVVE------- 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1669 aEELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKNL------VERLKNQLALKEKQLKALSK---ALLELRAELTS 1739
Cdd:pfam12128  725 -GALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLgvdpdvIAKLKREIRTLERKIERIAVrrqEVLRYFDWYQE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1740 QAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQ 1819
Cdd:pfam12128  804 TWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQ 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1820 SEKEALE--EHLNELKKKIQRLSsglqaqvesdgptvDALQKKIRKLEHELDRKSISEPADKRSTLKEDKSSK-EEVVRW 1896
Cdd:pfam12128  884 AQGSIGErlAQLEDLKLKRDYLS--------------ESVKKYVEHFKNVIADHSGSGLAETWESLREEDHYQnDKGIRL 949

                          810       820
                   ....*....|....*....|....
gi 688616512  1897 EEGKKWQARVDKMRNVLKEKEREV 1920
Cdd:pfam12128  950 LDYRKLVPYLEQWFDVRVPQSIMV 973
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 108-210 1.27e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 44.56  E-value: 1.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  108 HFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAeQR 187
Cdd:PRK11448  145 HALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERKQKRKEI-TD 223

                          90       100
                  ....*....|....*....|...
gi 688616512  188 ESLQTKEESNEIQRRLTkaNQQL 210
Cdd:PRK11448  224 QAAKRLELSEEETRILI--DQQL 244
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1522-1943 1.35e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1522 QTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIA------KRHEEEVRALHQKLDVYMDtsLDRFKQTALELIKKPTit 1595
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEeleaelEELREELEKLEKLLQLLPL--YQELEALEAELAELPE-- 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1596 vptskHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQMKGLSQEAEELRAQ 1675
Cdd:COG4717   147 -----RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEE 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1676 LIQMEKELHYLRTELEAQKEAN-----------------VRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELT 1738
Cdd:COG4717   222 LEELEEELEQLENELEAAALEErlkearlllliaaallaLLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLG 301

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1739 SQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDgVRAAKARENSLKEDLETLNKDLQRSQKSQNKL 1818
Cdd:COG4717   302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEE-LQELLREAEELEEELQLEELEQEIAALLAEAG 380

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1819 QSEKEALEEHL------NELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPADKRSTLKEDKSS-KE 1891
Cdd:COG4717   381 VEDEEELRAALeqaeeyQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAElEA 460

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 688616512 1892 EVVRWEEGK---KWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVS 1943
Cdd:COG4717   461 ELEQLEEDGelaELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLP 515
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 68-731 1.63e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    68 EVVDSAGAEQARIENELKAKVLKLESELEmaqrvmggGDKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELAL 147
Cdd:TIGR00618  176 DQYTQLALMEFAKKKSLHGKAELLTLRSQ--------LLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQ 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   148 RAEEAEEKNRKlKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANL 227
Cdd:TIGR00618  248 KREAQEEQLKK-QQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   228 RSENEHLQK---NLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRK---DRDHAKLQVRELT-----DQIQARVEEDDP 296
Cdd:TIGR00618  327 LMKRAAHVKqqsSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQqhtLTQHIHTLQQQKTtltqkLQSLCKELDILQ 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   297 VMAAVNAKVEEWKSVLSGKDLEI---LEYQQMIRDLREKLRTAQMDSDKSNIIALQQAVQ------ERDNQIKMLSEQVE 367
Cdd:TIGR00618  407 REQATIDTRTSAFRDLQGQLAHAkkqQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQslkereQQLQTKEQIHLQET 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   368 QYTTEMERNAMLIEELKRPLKKDKGHSSDHQ-------------RRLEDLSAKLQVAERKV-----LEAQRAAQLAERDA 429
Cdd:TIGR00618  487 RKKAVVLARLLELQEEPCPLCGSCIHPNPARqdidnpgpltrrmQRGEQTYAQLETSEEDVyhqltSERKQRASLKEQMQ 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   430 RDKDKELNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINN----LLDENEDLRERLGLN 505
Cdd:TIGR00618  567 EIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLqdvrLHLQQCSQELALKLT 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   506 PKEELDLS---EFRRSKILKQRQYKAEnqvllkEIERLEEERLELKQRIRALVKDKGVTVVSNSLL---DNSVEE--KPV 577
Cdd:TIGR00618  647 ALHALQLTltqERVREHALSIRVLPKE------LLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLrelETHIEEydREF 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   578 RSLRPSSGSTDDEIKRKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGV 657
Cdd:TIGR00618  721 NEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHL 800

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 688616512   658 SIPSLERLVNalEMKYSEGKFDASLHL----RTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEME 731
Cdd:TIGR00618  801 LKTLEAEIGQ--EIPSDEDILNLQCETlvqeEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSD 876
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 75-321 1.63e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 44.27  E-value: 1.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   75 AEQARieneLKAKVlkleSELEMAQRVMGGgdkhflRDEIRQLESHL-----ERKEKEVTQLEKEMGKERKSNEELAL-R 148
Cdd:PRK10929  180 AESAA----LKALV----DELELAQLSANN------RQELARLRSELakkrsQQLDAYLQALRNQLNSQRQREAERALeS 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  149 AEEAEEKNRKLKREIKQLTRKNEQLQQDIefyrKEAEQRESLQTKEesneiQRRLTKANQQLYQCMEELQhaeDMAANLR 228
Cdd:PRK10929  246 TELLAEQSGDLPKSIVAQFKINRELSQAL----NQQAQRMDLIASQ-----QRQAASQTLQVRQALNTLR---EQSQWLG 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  229 SEN---EHLQKNLEEsVKEMEKMtdeynkmkiavQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVN--- 302
Cdd:PRK10929  314 VSNalgEALRAQVAR-LPEMPKP-----------QQLDTEMAQLRVQRLRYEDLLNKQPQLRQIRQADGQPLTAEQNril 381

                         250       260
                  ....*....|....*....|....
gi 688616512  303 -----AKVEEWKSVLSGKDLEILE 321
Cdd:PRK10929  382 daqlrTQRELLNSLLSGGDTLILE 405
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 70-337 1.73e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 1.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    70 VDSAGAEQARIENELKAKVLKLESEL----EMAQRVMGGGDkhflrDEIRQLESHLERKEKEVTQLEKemgkerkSNEEL 145
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEqlleELNKKIKDLGE-----EEQLRVKEKIGELEAEIASLER-------SIAEK 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   146 ALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEaeqRESLQTKEESNEIQRRLTKAnqqlyqcmeELQHAEDMAA 225
Cdd:TIGR02169  314 ERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKR---RDKLTEEYAELKEELEDLRA---------ELEEVDKEFA 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   226 NLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELtdqiQARVEEDDPVMAAVNAKV 305
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINEL----EEEKEDKALEIKKQEWKL 457

                          250       260       270
                   ....*....|....*....|....*....|..
gi 688616512   306 EEWKSVLSGKDLEILEYQQMIRDLREKLRTAQ 337
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
988-1217 1.98e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  988 ERIDSINKELEISKEKLHTLEQAFEnisttggeiimdkatkavANSEIVSVSRRITTLEmkELNERQRAEHAQKMYEHLR 1067
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEPIRE------------------LAERYAAARERLAELE--YLRAALRLWFAQRRLELLE 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1068 NSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSvskhisdaDRKRITELEKTEANLRIEVSKLREVSDVAKM 1147
Cdd:COG4913   295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGN--------GGDRLEQLEREIERLERELEERERRRARLEA 366

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1148 QVSALDARQQSREKEVESLRRQVldyqaesdeKALIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQ 1217
Cdd:COG4913   367 LLAALGLPLPASAEEFAALRAEA---------AALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1659-1839 2.21e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1659 AAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKE-----ANVRSPSNTMKNlVERLKNQLALKEKQLKALSKALLEL 1733
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQErrealQRLAEYSWDEID-VASAEREIAELEAELERLDASSDDL 687

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1734 RaeltsQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENS-----LKEDLETLNKDL 1808
Cdd:COG4913   688 A-----ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLelralLEERFAAALGDA 762

                         170       180       190
                  ....*....|....*....|....*....|.
gi 688616512 1809 QRSQKSQNkLQSEKEALEEHLNELKKKIQRL 1839
Cdd:COG4913   763 VERELREN-LEERIDALRARLNRAEEELERA 792
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2484-2723 2.63e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 2.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2484 ENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELE------ETHQRLLLAQSKGATLLGVDSKTWKSSVVTRLFENk 2557
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEqlrkelEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL- 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2558 mKGLESDIAKKNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNVPVEATTDEG-LAREYQSVRLANKQLEREKAQ 2636
Cdd:TIGR02168  757 -TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTlLNEEAANLRERLESLERRIAA 835

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2637 LLRQIQRNEVQLGtnkdgpgytELQEQIKAANNEKKKLQDEVRKLTQELKHFD---PTFFEELEDLKFNYNLEVKKNIVL 2713
Cdd:TIGR02168  836 TERRLEDLEEQIE---------ELSEDIESLAAEIEELEELIEELESELEALLnerASLEEALALLRSELEELSEELREL 906

                          250
                   ....*....|
gi 688616512  2714 EEQLKKLSDQ 2723
Cdd:TIGR02168  907 ESKRSELRRE 916
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
117-256 2.72e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 43.31  E-value: 2.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  117 LESHLERKEKEVtqLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEfyrkeaEQRESLQtkees 196
Cdd:COG2433   378 IEEALEELIEKE--LPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELE------EKDERIE----- 444

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  197 nEIQRRLTKANQQLYQCMEELQHAEdmaaNLRSENEHLQKNLEESVKEMEKMTDEYNKMK 256
Cdd:COG2433   445 -RLERELSEARSEERREIRKDREIS----RLDREIERLERELEEERERIEELKRKLERLK 499
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
152-444 2.77e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 2.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  152 AEEKNRKLKREIKQLTRKNEQLQQDIEfyrKEAEQRESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSEN 231
Cdd:COG4913   608 NRAKLAALEAELAELEEELAEAEERLE---ALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASS 684

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  232 ---EHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDdpvmaavnakVEEW 308
Cdd:COG4913   685 ddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL----------LEER 754

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  309 KSVLSGKDLEileyQQMIRDLREKLRTA--QMDSDKSNIIALQQAVQERDNqikmlsEQVEQYTTEMERNAMLIEELKRp 386
Cdd:COG4913   755 FAAALGDAVE----RELRENLEERIDALraRLNRAEEELERAMRAFNREWP------AETADLDADLESLPEYLALLDR- 823

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 688616512  387 LKKDKGHssDHQRRLEDLsaKLQVAERKVLEAQRAAQLAERDARDKDKELNDTLSRIR 444
Cdd:COG4913   824 LEEDGLP--EYEERFKEL--LNENSIEFVADLLSKLRRAIREIKERIDPLNDSLKRIP 877
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1145-1390 2.81e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1145 AKMQVSALDARQQSREKEVESLRRQVLDYQAEsdekalIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQK 1224
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQ------LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1225 LDEQQQALwhARQEGHQRARHLRHTIQALRRQFSGALPLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQEL 1304
Cdd:COG4942    99 LEAQKEEL--AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1305 ELKLKGLEELIATLKDAKGAQKvsewhKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLE 1384
Cdd:COG4942   177 EALLAELEEERAALEALKAERQ-----KLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251


                  ....*.
gi 688616512 1385 ERQLIW 1390
Cdd:COG4942   252 KGKLPW 257
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 118-314 2.84e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 2.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  118 ESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRE--------S 189
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERReelgerarA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  190 LQTKEESN-------------------EIQRRLTKANQQLyqcMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTD 250
Cdd:COG3883    95 LYRSGGSVsyldvllgsesfsdfldrlSALSKIADADADL---LEELKADKAELEAKKAELEAKLAELEALKAELEAAKA 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 688616512  251 EYNKmkiAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSG 314
Cdd:COG3883   172 ELEA---QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 684-835 2.89e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 2.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  684 LRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSKS---TGSSIPHKTLAL----PEEMTpTS 756
Cdd:COG3883    42 LQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAlyrSGGSVSYLDVLLgsesFSDFL-DR 120

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616512  757 AEAINALNEYTVQLLQEIKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQRE 835
Cdd:COG3883   121 LSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLA 199
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 110-465 3.04e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 3.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   110 LRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRES 189
Cdd:TIGR00606  693 LQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQET 772

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   190 L----------------------QTKEESNEIQRR------------LTKANQQLYQCMEELQHAEDMAANLRSENEHLQ 235
Cdd:TIGR00606  773 LlgtimpeeesakvcltdvtimeRFQMELKDVERKiaqqaaklqgsdLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLI 852

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   236 KNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGK 315
Cdd:TIGR00606  853 QDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSK 932

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   316 DLEILEYQQMIRDLREKLRTA---QMDSDKSNIIALQQAVQERDNQIKMLSEQVEQYTTEMERnamlIEELKRPLKKDKG 392
Cdd:TIGR00606  933 ETSNKKAQDKVNDIKEKVKNIhgyMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEK----INEDMRLMRQDID 1008

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   393 HSSDHQRRLEDLSAKL------------------QVAERKVLEAQRAAQLAERDARDKDKELNDTLSRIRLYESGTDGLE 454
Cdd:TIGR00606 1009 TQKIQERWLQDNLTLRkrenelkeveeelkqhlkEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFK 1088

                          410
                   ....*....|.
gi 688616512   455 AAISEiKECKN 465
Cdd:TIGR00606 1089 KELRE-PQFRD 1098
PRK11281 PRK11281
mechanosensitive channel MscK;
137-368 3.47e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.98  E-value: 3.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  137 KERKSNEELALRAEEAEEKNRKLKREIKQLTRKNeqlqqdiefyrkEAEQRESLQtKEESNEIQRRLTKANQQLYQCMEE 216
Cdd:PRK11281   77 RQKEETEQLKQQLAQAPAKLRQAQAELEALKDDN------------DEETRETLS-TLSLRQLESRLAQTLDQLQNAQND 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  217 LQHAEDMAANLRSENEHLQKNLEEsvkemekmtdeynkmkiAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARveeddp 296
Cdd:PRK11281  144 LAEYNSQLVSLQTQPERAQAALYA-----------------NSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAE------ 200

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 688616512  297 vMAAVNAKVEEWKSVLSGKDLEILEYQQmIRDlrekLRTAQMDSDKSNIIALQQAVQERdnQIKMLSEQVEQ 368
Cdd:PRK11281  201 -QALLNAQNDLQRKSLEGNTQLQDLLQK-QRD----YLTARIQRLEHQLQLLQEAINSK--RLTLSEKTVQE 264
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 805-1445 3.54e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.03  E-value: 3.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   805 LYKEHQSERESWQKERDSFAELKSKLEEQREVDavkikeynhlleTLEKDPSEIRREMAETGRKIVVLRVNEKCLTRR-- 882
Cdd:TIGR00618  224 LEKELKHLREALQQTQQSHAYLTQKREAQEEQL------------KKQQLLKQLRARIEELRAQEAVLEETQERINRArk 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   883 YTTLLELEQHLRKENAKLKEDFTQMQAAVTERIGYLQRFKemaafkmASLQKSLDVSVPASELERANKQYTELTIKYRNL 962
Cdd:TIGR00618  292 AAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRA-------AHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVA 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   963 LQKDNHLVQKTTSLEHLETenmsLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKATKAVANSEIVSVSRRI 1042
Cdd:TIGR00618  365 TSIREISCQQHTLTQHIHT----LQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1043 TTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELET-------KFAELTKLNLEAQRIERELRDEL----ADSVSK 1111
Cdd:TIGR00618  441 ELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQihlqetrKKAVVLARLLELQEEPCPLCGSCihpnPARQDI 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1112 HISDADRKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALIAKLHQHIV 1191
Cdd:TIGR00618  521 DNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLT 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1192 ALQLSETtaISRLEATNTRLQKLEAQ------KLRDEQKLDEQQQALWHARQEGHQRARHlRHTIQALRRQFSGALPLAQ 1265
Cdd:TIGR00618  601 EKLSEAE--DMLACEQHALLRKLQPEqdlqdvRLHLQQCSQELALKLTALHALQLTLTQE-RVREHALSIRVLPKELLAS 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1266 QEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEdvrllEMRQS 1345
Cdd:TIGR00618  678 RQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKE-----LMHQA 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1346 RELNTQREEIKYLKN---CVAEQERT-ISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEA 1421
Cdd:TIGR00618  753 RTVLKARTEAHFNNNeevTAALQTGAeLSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQ 832

                          650       660
                   ....*....|....*....|....
gi 688616512  1422 TGSLPDPNQPLANQLDYALGKIKE 1445
Cdd:TIGR00618  833 FLSRLEEKSATLGEITHQLLKYEE 856
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 113-254 3.81e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 3.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  113 EIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKeAEQRESLQT 192
Cdd:COG1579    18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN-NKEYEALQK 96

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 688616512  193 KEESNEiqRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNK 254
Cdd:COG1579    97 EIESLK--RRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA 156
PRK12704 PRK12704
phosphodiesterase; Provisional
 2417-2522 3.97e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 3.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2417 KKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKGKQEEQLNSR---LESKTKGIEKIMMENERLRKEIK 2493
Cdd:PRK12704   41 KRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKeenLDRKLELLEKREEELEKKEKELE 120

                          90       100
                  ....*....|....*....|....*....
gi 688616512 2494 KEAEAAEKLrvaKASLEVANEKLKAELEE 2522
Cdd:PRK12704  121 QKQQELEKK---EEELEELIEEQLQELER 146
TMCO5 pfam14992
TMCO5 family; The TMCO5 family includes human transmembrane and coiled-coil domain-containing ...
 129-252 4.05e-03

TMCO5 family; The TMCO5 family includes human transmembrane and coiled-coil domain-containing proteins 5A and 5B.


Pssm-ID: 464427 [Multi-domain]  Cd Length: 278  Bit Score: 41.63  E-value: 4.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   129 TQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQlTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEiqrRLTKANQ 208
Cdd:pfam14992    6 SDLEKDLQRLDEANQVLLLKIQEKEEEIQSLEREITL-TRSLAEDEEREELNFTIMEKEDALQELELETA---KLEKKNE 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   209 QLYQCMEELQHAEDMA--ANLRSENEHLQKNLEESV--------------KEMEKMTDEY 252
Cdd:pfam14992   82 ILVKSVMELQRKLSRKsdKNTGLEQETLKQMLEELKvklqqseescadqeKELAKVESDY 141
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1604-2012 4.08e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 4.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1604 RLAEMEQTVAEQDNSLSSLSQKLKIvtQELDQQRQVTAAQAMEHAADMARLEDKHAaQMKGLSQEAEELRAQLIQMEKEL 1683
Cdd:COG4717   103 ELEELEAELEELREELEKLEKLLQL--LPLYQELEALEAELAELPERLEELEERLE-ELRELEEELEELEAELAELQEEL 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1684 HYLRTELEAQKEANVRSPSNTMKNL---VERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQ 1760
Cdd:COG4717   180 EELLEQLSLATEEELQDLAEELEELqqrLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALL 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1761 IVDKQTKELRACVRDLNEELQLAkdgVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLS 1840
Cdd:COG4717   260 ALLGLGGSLLSLILTIAGVLFLV---LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSP 336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1841 SGLQAQVEsDGPTVDALQKKIRKLEHELDRKSISEpaDKRSTLKEDKSSKEE-----VVRWEEGKKWQARVDKMRNVLKE 1915
Cdd:COG4717   337 EELLELLD-RIEELQELLREAEELEEELQLEELEQ--EIAALLAEAGVEDEEelraaLEQAEEYQELKEELEELEEQLEE 413

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1916 KEREVDSQAKQLAtmkelYSRLEQEKVSLQKKLKgrgvtadqvvgartlEADKEIEELHKRNAELEQQIKVMKQQQALPR 1995
Cdd:COG4717   414 LLGELEELLEALD-----EEELEEELEELEEELE---------------ELEEELEELREELAELEAELEQLEEDGELAE 473

                         410
                  ....*....|....*...
gi 688616512 1996 -DAAMEDITNRNRYLEER 2012
Cdd:COG4717   474 lLQELEELKAELRELAEE 491
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1732-1878 4.27e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.96  E-value: 4.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1732 ELRAELtSQAEQQIITnAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKdgvRAAKARENSLKEDLETLNkDLQRS 1811
Cdd:COG1566    80 DLQAAL-AQAEAQLAA-AEAQLARLEAELGAEAEIAAAEAQLAAAQAQLDLAQ---RELERYQALYKKGAVSQQ-ELDEA 153

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616512 1812 QKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVEsdgptVDALQKKIRKLEHELDRKSISEPAD 1878
Cdd:COG1566   154 RAALDAAQAQLEAAQAQLAQAQAGLREEEELAAAQAQ-----VAQAEAALAQAELNLARTTIRAPVD 215
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1763-1992 4.33e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 4.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1763 DKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSG 1842
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1843 LQAQvESDGPTVDALqkkirkleheLDRKSISEPADKRSTLKEDKSSKEEVVrwEEGKKWQARVDKMRNVLKEKEREVDS 1922
Cdd:COG3883    95 LYRS-GGSVSYLDVL----------LGSESFSDFLDRLSALSKIADADADLL--EELKADKAELEAKKAELEAKLAELEA 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1923 QAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAELEQQIKVMKQQQA 1992
Cdd:COG3883   162 LKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1756-2010 4.54e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 4.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1756 LNVQQIVDKQTKELRACVRDLNEELQLAKDGV---RAAKARENSLKEDLETLNKdlQRSQKSQNKLQSEKEALEEHLNEL 1832
Cdd:PRK05771   28 LGVVHIEDLKEELSNERLRKLRSLLTKLSEALdklRSYLPKLNPLREEKKKVSV--KSLEELIKDVEEELEKIEKEIKEL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1833 KKKIQRLSSglqaqvesdgptvdalqkKIRKLEHELDR----KSIS-EPADKRS---------TLKEDKSSKEEVVrWEE 1898
Cdd:PRK05771  106 EEEISELEN------------------EIKELEQEIERlepwGNFDlDLSLLLGfkyvsvfvgTVPEDKLEELKLE-SDV 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1899 GKKWQARVDKMRN-----VLKEKEREVDSQAKQL----------ATMKELYSRLEQEKVSLQKKLKgrgvtadqvvgart 1963
Cdd:PRK05771  167 ENVEYISTDKGYVyvvvvVLKELSDEVEEELKKLgferleleeeGTPSELIREIKEELEEIEKERE-------------- 232

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 688616512 1964 lEADKEIEELHKRNAELEQQIK-----VMKQQQALPRDAamedITNRNRYLE 2010
Cdd:PRK05771  233 -SLLEELKELAKKYLEELLALYeyleiELERAEALSKFL----KTDKTFAIE 279
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 683-1285 4.59e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 4.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  683 HLRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSkstgssiphktlalpeemtptsaEAINA 762
Cdd:COG1196   236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ-----------------------AEEYE 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  763 LNEYTVQLLQEIKNKGDSIEQLGSALEEYKRkfavirhqqgllykehqsERESWQKERDSFAELKSKLEEQREVDAVKIK 842
Cdd:COG1196   293 LLAELARLEQDIARLEERRRELEERLEELEE------------------ELAELEEELEELEEELEELEEELEEAEEELE 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  843 EYNHLLETLEKDPSEIRREMAETGRKIVvlrvnekcltRRYTTLLELEQHLRKENAKLKEDFTQMQAAVTERIGYLQRFK 922
Cdd:COG1196   355 EAEAELAEAEEALLEAEAELAEAEEELE----------ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE 424

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  923 EMAAFKMASLQKSLDVSVPASELERAnkqyteltikyrnLLQKDNHLVQKTTSLEHLETENMSLRERIDSINKELEISKE 1002
Cdd:COG1196   425 ELEEALAELEEEEEEEEEALEEAAEE-------------EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1003 KLHTLEQAFENISTTGGEIImdKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELET 1082
Cdd:COG1196   492 RLLLLLEAEADYEGFLEGVK--AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1083 KFAELTKLNLEAQRIERELRDELADSVS-KHISDADRKRITELEKTEANLRIEVSKLREVSDVAkmQVSALDARQQSREK 1161
Cdd:COG1196   570 KAGRATFLPLDKIRARAALAAALARGAIgAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE--AALRRAVTLAGRLR 647

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1162 EVESLRRQVLDYQAESDEKALIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQ 1241
Cdd:COG1196   648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALE 727

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....
gi 688616512 1242 RARHLRHTIQALRRQFSGALPLAQQEKFSNTMLHLQEDRARVRE 1285
Cdd:COG1196   728 EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1660-1878 4.63e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.58  E-value: 4.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1660 AQMKGLSQE---AEELRAQLIQMEKEL-----------HYLRTELEAQKEANVrspsnTMKNLVERLK----------NQ 1715
Cdd:PLN02939  184 ARIKLAAQEkihVEILEEQLEKLRNELlirgateglcvHSLSKELDVLKEENM-----LLKDDIQFLKaelievaeteER 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1716 LALKEKQLKALSKALLELRAELTSqAEQQIITNAAQKEEAL-----NVQQIVDKQTK--ELRACVRDLNEELQLAKDGVR 1788
Cdd:PLN02939  259 VFKLEKERSLLDASLRELESKFIV-AQEDVSKLSPLQYDCWwekveNLQDLLDRATNqvEKAALVLDQNQDLRDKVDKLE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1789 AAKARENSLKEDLETLnkDLqrsqksqnkLQSEKEALEEHLnelkkkiQRLSSGLQAQVESDGPTVDALQKKIRKLEHEL 1868
Cdd:PLN02939  338 ASLKEANVSKFSSYKV--EL---------LQQKLKLLEERL-------QASDHEIHSYIQLYQESIKEFQDTLSKLKEES 399

                         250
                  ....*....|
gi 688616512 1869 DRKSISEPAD 1878
Cdd:PLN02939  400 KKRSLEHPAD 409
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2408-2684 4.83e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 4.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2408 ELEKTIGLMKKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKlkGKQEEQLNSRLESKTKGIEKIMMENER 2487
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL--LAELARLEQDIARLEERRRELEERLEE 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2488 LRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEETHQRLLLAQSKGATLlgvdsktwkssvvtrlfENKMKGLESDIAK 2567
Cdd:COG1196   321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA-----------------EAELAEAEEELEE 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2568 KNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNvpvEATTDEGLAREYQSVRLANKQLEREKAQLLRQIQRNEVQ 2647
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 688616512 2648 LGTNKDGPGYTELQEQIKAANNEKKKLQDEVRKLTQE 2684
Cdd:COG1196   461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
46 PHA02562
endonuclease subunit; Provisional
 157-399 5.16e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 5.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  157 RKLKREIKQLTRKNEQLQQDIEFYRKEAEQreslqtkeesneiQRRLTKANQQLYQCMEElQHAEDmAANLRSENEHLQK 236
Cdd:PHA02562  177 RELNQQIQTLDMKIDHIQQQIKTYNKNIEE-------------QRKKNGENIARKQNKYD-ELVEE-AKTIKAEIEELTD 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  237 NLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKD----RDHAKLQVreLTDQIqarvEEDDPVMAAVNAKVEEWKSVL 312
Cdd:PHA02562  242 ELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVikmyEKGGVCPT--CTQQI----SEGPDRITKIKDKLKELQHSL 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  313 SGKDLEILEYQQMIRDLREKLRTAQmdSDKSNIIALQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKG 392
Cdd:PHA02562  316 EKLDTAIDELEEIMDEFNEQSKKLL--ELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVK 393


                  ....*..
gi 688616512  393 HSSDHQR 399
Cdd:PHA02562  394 TKSELVK 400
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 782-1576 5.21e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.27  E-value: 5.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   782 EQLGSALEEYKRKFAVIRHQQGLLYKEH--QSERESWQKERDSFAELKSKLEEQREVDAVKIKEYNHLLETLEKDPSEIR 859
Cdd:pfam02463  213 YQLKEKLELEEEYLLYLDYLKLNEERIDllQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   860 REMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQAAVTERIGYLQRFKEMAAFKMASLQKSLDV- 938
Cdd:pfam02463  293 KEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLe 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   939 -SVPASELERANKQYTELTIKYRNLLQKDNHLVQKTTSLEHLETENMSLRERIdsiNKELEISKEKLHTLEQAFENISTT 1017
Cdd:pfam02463  373 eELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEK---KEELEILEEEEESIELKQGKLTEE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1018 GGEIIMDKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRI 1097
Cdd:pfam02463  450 KEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHG 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1098 ERELRDELADSVSKHISDAD-------------------RKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQS 1158
Cdd:pfam02463  530 RLGDLGVAVENYKVAISTAVivevsatadeveerqklvrALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLD 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1159 REKEVESLRRQVLDYQAESDEKALIAKLHQHIVALQ--LSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHAR 1236
Cdd:pfam02463  610 KATLEADEDDKRAKVVEGILKDTELTKLKESAKAKEsgLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESEL 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1237 QEGHQRARHLRHTIQALRRQFSGALPLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAE--GKAQELELKLKGLEEL 1314
Cdd:pfam02463  690 AKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEeeKSRLKKEEKEEEKSEL 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1315 IATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQRE 1394
Cdd:pfam02463  770 SLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLE 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1395 VQLERQLDSYEKQQNEVLNTAQKfEEATGSLPDPNQPLANQLDYALGKIKEHvrtILETKTTCKILEEKlKEKEAALWSS 1474
Cdd:pfam02463  850 KLAEEELERLEEEITKEELLQEL-LLKEEELEEQKLKDELESKEEKEKEEKK---ELEEESQKLNLLEE-KENEIEERIK 924

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  1475 EQNVLSRDKVINELRLRLPAAAEREKLLADLSKQEDSESQPTLKVAHQTINNLqGRLDQKEEVLKKYQNLLGKARQEQEE 1554
Cdd:pfam02463  925 EEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNL-MAIEEFEEKEERYNKDELEKERLEEE 1003

                          810       820
                   ....*....|....*....|..
gi 688616512  1555 IAKRHEEEVRALHQKLDVYMDT 1576
Cdd:pfam02463 1004 KKKLIRAIIEETCQRLKEFLEL 1025
PTZ00121 PTZ00121
MAEBL; Provisional
 148-868 5.68e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 5.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  148 RAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRrltkanqqlyqcMEELQHAEDMAANL 227
Cdd:PTZ00121 1088 RADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARK------------AEEARKAEDAKRVE 1155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  228 RSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEE 307
Cdd:PTZ00121 1156 IARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEA 1235

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  308 WKSVLSGKDLEILEYQQMIRDLREklrtAQMDSDKSNIIALQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPl 387
Cdd:PTZ00121 1236 KKDAEEAKKAEEERNNEEIRKFEE----ARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKK- 1310

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  388 KKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDKDKELndtlsrirlyESGTDGLEAAISEIKECKNQI 467
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEA----------EAAEEKAEAAEKKKEEAKKKA 1380

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  468 RVRDREIEgMIKEINQLEMKINNLLDENEDLRERLGLNPKEEldlsEFRRSKILKQRQYKAENQVLLKEIERLEEERLEL 547
Cdd:PTZ00121 1381 DAAKKKAE-EKKKADEAKKKAEEDKKKADELKKAAAAKKKAD----EAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEE 1455

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  548 KQRIRALVKDKGVTVVSNSLLDNSVEEKPVRSLRPSSgstdDEIKRKNERLQKELSNKEKELELRRSESTQ--------- 618
Cdd:PTZ00121 1456 AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKA----EEAKKKADEAKKAAEAKKKADEAKKAEEAKkadeakkae 1531

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  619 --------FKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGVSIPSLERLVNALEMKYSEGKFDASLHLRTQVDQ 690
Cdd:PTZ00121 1532 eakkadeaKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEE 1611

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  691 LTGRNEE-LRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSKStgSSIPHKTLALPEEMTPTSAEAINALNEYTVQ 769
Cdd:PTZ00121 1612 AKKAEEAkIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEE--NKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK 1689

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  770 LLQEIKNKGDS---IEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVDAVKIKEYNH 846
Cdd:PTZ00121 1690 AAEALKKEAEEakkAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769

                         730       740
                  ....*....|....*....|..
gi 688616512  847 LLETLEKDPSEIRREMAETGRK 868
Cdd:PTZ00121 1770 AEEIRKEKEAVIEEELDEEDEK 1791
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 1705-2036 6.10e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 42.34  E-value: 6.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1705 MKNLVERLKNQL----ALKEKQLKALSKAllelRAELTSQAEQQIIT---NAAQKEEALNVQQIVDKQTKELRACVRDLN 1777
Cdd:PTZ00108 1004 LERELARLSNKVrfikHVINGELVITNAK----KKDLVKELKKLGYVrfkDIIKKKSEKITAEEEEGAEEDDEADDEDDE 1079

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1778 EELQLAKDGVRAAKARENSL-KEDLETLNKDLQRSQKSQNKLQSE-------------KEALEEHLNELKKKIQRLSSGL 1843
Cdd:PTZ00108 1080 EELGAAVSYDYLLSMPIWSLtKEKVEKLNAELEKKEKELEKLKNTtpkdmwledldkfEEALEEQEEVEEKEIAKEQRLK 1159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1844 QAQVESDGPtvdaLQKKIRKLEHELDRKSISEPADKRSTLKEDKSSKEEVVRweegKKWQARVDKMRNVLKEKEREVDSQ 1923
Cdd:PTZ00108 1160 SKTKGKASK----LRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKR----KLDDKPDNKKSNSSGSDQEDDEEQ 1231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1924 AKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAELEQQIKVMKQQQALPRDAAMEDIT 2003
Cdd:PTZ00108 1232 KTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVK 1311

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 688616512 2004 NRNRYL--------EERLYSMESRLSKEPPSRPSDRHSTSP 2036
Cdd:PTZ00108 1312 KRLEGSlaalkkkkKSEKKTARKKKSKTRVKQASASQSSRL 1352
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 106-512 6.46e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.93  E-value: 6.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   106 DKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNE---ELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFyrk 182
Cdd:TIGR04523  174 ELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISN--- 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   183 eaEQRESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSE------------NEHLQKNLEESVKEMEKMTD 250
Cdd:TIGR04523  251 --TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEisdlnnqkeqdwNKELKSELKNQEKKLEEIQN 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   251 EYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGK---DLEILEYQQMIR 327
Cdd:TIGR04523  329 QISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQIndlESKIQNQEKLNQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   328 DLREKLRTAQMDSDK--SNIIALQQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLS 405
Cdd:TIGR04523  409 QKDEQIKKLQQEKELleKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   406 AKLQVAERKVLEAQRAAQLAERDARDKDKELNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVR------DREIEGMIK 479
Cdd:TIGR04523  489 KELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFElkkenlEKEIDEKNK 568

                          410       420       430
                   ....*....|....*....|....*....|...
gi 688616512   480 EINQLEMKINNLLDENEDLRERLGLNPKEELDL 512
Cdd:TIGR04523  569 EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDL 601
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
82-279 6.70e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 6.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   82 NELKAKVLKLESELEMAQRvmgggdkhfLRDEIRQLESHLERKEKEVTQLEKEMGKER-KSNEELALRAEEAE------- 153
Cdd:PRK03918  535 IKLKGEIKSLKKELEKLEE---------LKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEpfyneyl 605

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  154 -------------EKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRRLTKANQQLYQCMEELQHA 220
Cdd:PRK03918  606 elkdaekelereeKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEEL 685

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 688616512  221 EDmaanLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQ 279
Cdd:PRK03918  686 EK----RREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKER 740
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1631-1813 6.88e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 6.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1631 QELDQQRQVTAAQAMEHAADMARLEDKHAA--QMKGLSQEAEELRAQLIQMEkELHYLRTELEAQKEAnVRSPSNTmknl 1708
Cdd:COG4913   613 AALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVA-SAEREIAELEAELER-LDASSDD---- 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1709 VERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQIVDKQTKELRAcvrDLNEELQLAKDGVR 1788
Cdd:COG4913   687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA---LLEERFAAALGDAV 763

                         170       180
                  ....*....|....*....|....*
gi 688616512 1789 AAKARENsLKEDLETLNKDLQRSQK 1813
Cdd:COG4913   764 ERELREN-LEERIDALRARLNRAEE 787
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
977-1179 6.92e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 6.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  977 EHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKATKAVANseivsvsrRITTLEMKELNERQRA 1056
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQ--------QLSELESQLAEARAEL 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1057 EHAQKMYEHLRNSLKQVEERNFELETKfAELTKLNLEAQRIERELRDELADSVSKHIsdadrkRITELEKTEANLRIEVS 1136
Cdd:COG3206   236 AEAEARLAALRAQLGSGPDALPELLQS-PVIQQLRAQLAELEAELAELSARYTPNHP------DVIALRAQIAALRAQLQ 308

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 688616512 1137 K-LREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDE 1179
Cdd:COG3206   309 QeAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAE 352
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1275-1376 7.04e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.77  E-value: 7.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1275 HLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKD--AKGAQKVSEWHKKLEDVRL---LEMRQSRELN 1349
Cdd:COG2433   389 ELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAelEEKDERIERLERELSEARSeerREIRKDREIS 468

                          90       100
                  ....*....|....*....|....*..
gi 688616512 1350 TQREEIKYLKNCVAEQERTISGLEEEL 1376
Cdd:COG2433   469 RLDREIERLERELEEERERIEELKRKL 495
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1695-1870 7.16e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 7.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1695 EANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQI-VDKQTKELRACV 1773
Cdd:COG3206   163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAeARAELAEAEARL 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1774 RDLNEELQLAKDGVRAAKA--RENSLKEDLETLNKDL----QRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQV 1847
Cdd:COG3206   243 AALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELaelsARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAEL 322

                         170       180
                  ....*....|....*....|...
gi 688616512 1848 ESDGPTVDALQKKIRKLEHELDR 1870
Cdd:COG3206   323 EALQAREASLQAQLAQLEARLAE 345
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
75-462 7.27e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 7.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   75 AEQARIENELKAKVLKLESELEMAQRVmgggdkHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSN-EELALRAEEAE 153
Cdd:COG4717   132 QELEALEAELAELPERLEELEERLEEL------RELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQ 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  154 EKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRS---- 229
Cdd:COG4717   206 QRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLvlgl 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  230 ---ENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEeddpvmaaVNAKVE 306
Cdd:COG4717   286 lalLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQE--------LLREAE 357

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  307 EWKsvlsgKDLEILEYQQMIRDLrekLRTAQMDSDKS--NIIALQQAVQERDNQIKMLSEQVEQYTTEMERNAMLI--EE 382
Cdd:COG4717   358 ELE-----EELQLEELEQEIAAL---LAEAGVEDEEElrAALEQAEEYQELKEELEELEEQLEELLGELEELLEALdeEE 429

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  383 LKRPLKKDKGHSSDHQRRLEDLSAKLQ--VAERKVLEAQRAAQLAERDARDKDKELNDTLSRIRLYESGTDGLEAAISEI 460
Cdd:COG4717   430 LEEELEELEEELEELEEELEELREELAelEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEY 509


                  ..
gi 688616512  461 KE 462
Cdd:COG4717   510 RE 511
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 112-225 7.40e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.99  E-value: 7.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  112 DEIRQLESHLERKEKEVTQLEKEmgKERKSNEELA-LRAEEAEeknrkLKREIKQLTRKNEQLQQDIEFYRKEAEQREsl 190
Cdd:COG0542   411 EELDELERRLEQLEIEKEALKKE--QDEASFERLAeLRDELAE-----LEEELEALKARWEAEKELIEEIQELKEELE-- 481

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 688616512  191 QTKEESNEIQRRLTKANQQLYQCMEELQH---AEDMAA 225
Cdd:COG0542   482 QRYGKIPELEKELAELEEELAELAPLLREevtEEDIAE 519
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2358-2520 8.52e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 8.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2358 LEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVE---------KRLNHLRGSGRSGKTIPE--LEKTIGLMKKVVEKVQRE 2426
Cdd:PRK05771   95 LEKIEKEIKELEEEISELENEIKELEQEIERLEpwgnfdldlSLLLGFKYVSVFVGTVPEdkLEELKLESDVENVEYIST 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2427 NENLKRTSEVNVQEQLATLERDHEKLksEYEKLKGKQEEQLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAk 2506
Cdd:PRK05771  175 DKGYVYVVVVVLKELSDEVEEELKKL--GFERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLA- 251

                         170
                  ....*....|....
gi 688616512 2507 ASLEVANEKLKAEL 2520
Cdd:PRK05771  252 LYEYLEIELERAEA 265
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 2051-2259 8.93e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.52  E-value: 8.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2051 DVIEAEQTQSSLLNSTVVVTEKEISVIEDKATQtsfrsidmgtAEVNQDDENVAKNKIDLEQKALMKDDKTEQEESNKEK 2130
Cdd:TIGR00927  634 DVAEAEHTGERTGEEGERPTEAEGENGEESGGE----------AEQEGETETKGENESEGEIPAERKGEQEGEGEIEAKE 703

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512  2131 GSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAE----ELESELTHREMMEKPLDEDQLEVENE------------ET 2194
Cdd:TIGR00927  704 ADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEevedEGEGEAEGKHEVETEGDRKETEHEGEteaegkededegEI 783

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 688616512  2195 NAEEMlySTMNQAELETPKVLLEGDEDYGQEPEELLKCECDPSAESKELDEEETALSNSTTFDAK 2259
Cdd:TIGR00927  784 QAGED--GEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAK 846
PRK12704 PRK12704
phosphodiesterase; Provisional
 2415-2522 9.16e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 9.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 2415 LMKKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKGKQE--EQLNSRLESKTKGIEKIMMENERLRKEI 2492
Cdd:PRK12704   54 IKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLEllEKREEELEKKEKELEQKQQELEKKEEEL 133

                          90       100       110
                  ....*....|....*....|....*....|..
gi 688616512 2493 -KKEAEAAEKL-RVAKASLEVANEKLKAELEE 2522
Cdd:PRK12704  134 eELIEEQLQELeRISGLTAEEAKEILLEKVEE 165
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 37-834 9.32e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.50  E-value: 9.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512    37 LKADDSEKMIQLFRISQTLLRMKLDEIKCAYEVVDSAGAEQARIENELKAKVLKLESELEmaQRVMGGGDKHFLRDEIRQ 116
Cdd:pfam02463  248 DEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLER--RKVDDEEKLKESEKEKKK 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   117 LESHLERKEKEVTQLEKEM-------GKERKSNEELALRAEEAEEKNRKLKREIKQLTRkneqlqqdiefyRKEAEQRES 189
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELkeleikrEAEEEEEEELEKLQEKLEQLEEELLAKKKLESE------------RLSSAAKLK 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   190 LQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTD-AIMDQ 268
Cdd:pfam02463  394 EEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELkKSEDL 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   269 LRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREklrtaQMDSDKSNIIAL 348
Cdd:pfam02463  474 LKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGV-----AVENYKVAISTA 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   349 QQAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAERD 428
Cdd:pfam02463  549 VIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGI 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   429 ARDKDKELNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVRDReiegmiKEINQLEMKINNLLDENEDLRERLGLNPKE 508
Cdd:pfam02463  629 LKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELT------KELLEIQELQEKAESELAKEEILRRQLEIK 702

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   509 ELDLSEFRRSKILKQRQYKAENQVLLKEIERLEEERLELKQRIRALVKDKGVTVVSNSLLDNSVEEKPVRSLRPSSGSTD 588
Cdd:pfam02463  703 KKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREK 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   589 DEIKRKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGVSIPSLERLVNA 668
Cdd:pfam02463  783 TEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   669 LEMKYSEGKFDASLHLRTQVDQLTgRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSKstgssIPHKTLAL 748
Cdd:pfam02463  863 ITKEELLQELLLKEEELEEQKLKD-ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAE-----ILLKYEEE 936

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512   749 PEEMTPTSAEAINALNEYTVQLLQEIKNKGDSIEQLGSALEEYKRKFAVIRHQqgllYKEHQSERESWQKERDSFAELKS 828
Cdd:pfam02463  937 PEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEER----YNKDELEKERLEEEKKKLIRAII 1012


                   ....*.
gi 688616512   829 KLEEQR 834
Cdd:pfam02463 1013 EETCQR 1018
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1738-1983 9.92e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 9.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1738 TSQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQksqnk 1817
Cdd:COG3883    11 PAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERR----- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1818 lqsekEALEEHLNELKKKiQRLSSGLQAQVESDGPTvDALQK--KIRKLEhELDRKSISEPADKRSTLKEDKSSKEevvr 1895
Cdd:COG3883    86 -----EELGERARALYRS-GGSVSYLDVLLGSESFS-DFLDRlsALSKIA-DADADLLEELKADKAELEAKKAELE---- 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616512 1896 wEEGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHK 1975
Cdd:COG3883   154 -AKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232


                  ....*...
gi 688616512 1976 RNAELEQQ 1983
Cdd:COG3883   233 AAAAAAAA 240
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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