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Conserved domains on  [gi|688616510|ref|XP_009296179|]
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centrosomal protein of 290 kDa isoform X1 [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CEP209_CC5 pfam16574
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ...
 1279-1406 9.47e-46

Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.


:

Pssm-ID: 465184 [Multi-domain]  Cd Length: 128  Bit Score: 161.78  E-value: 9.47e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1279 TMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQ 1358
Cdd:pfam16574    1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 688616510  1359 REEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLER 1406
Cdd:pfam16574   81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1125-1992 3.74e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.52  E-value: 3.74e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1125 RKRITE--LEKTEANLRievsklrEVSDVAKmqvsaldarqqSREKEVESLRRQVLDYQAESDEKALIAKLHQHIVALQL 1202
Cdd:TIGR02168  173 RRKETErkLERTRENLD-------RLEDILN-----------ELERQLKSLERQAEKAERYKELKAELRELELALLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1203 -SETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRrqfsgalplAQQEKFSNTML 1281
Cdd:TIGR02168  235 eELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA---------NEISRLEQQKQ 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1282 HLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQ--KVSEWHKKLEDVRLLEMRQSRELNTQR 1359
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeaELEELEAELEELESRLEELEEQLETLR 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1360 EEIKYLKNCVAEQERTISGLEEELVQqnnlLEERQLIWDQREVQLERQLDSYEKQ--QNEVLNTAQKFEEATGSLPDPNQ 1437
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLER----LEDRRERLQQEIEELLKKLEEAELKelQAELEELEEELEELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1438 planqldyALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLrlpAAAEREKLLADLSKQED 1517
Cdd:TIGR02168  462 --------ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK---NQSGLSGILGVLSELIS 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1518 SESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLgkarqEQEEIAKRHEEEVRALH----QKLDVYMDTSLDRFKQTAL 1593
Cdd:TIGR02168  531 VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFL-----KQNELGRVTFLPLDSIKgteiQGNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1594 ELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLE-----DKHAAQ 1668
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILErrreiEELEEK 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1669 MKGLSQEAEELRAQLIQMEKELHYLRTELEA--QKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTS 1746
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQlrKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1747 QAEQQIITNAAQKEEALNVQQivdkqtkelracvrdLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQ 1826
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEE---------------LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1827 SEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPAdkRSTLKEDKSSKEEVVRweeg 1906
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA--LALLRSELEELSEELR---- 904

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1907 kkwqarvdKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAE 1986
Cdd:TIGR02168  905 --------ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976


                   ....*.
gi 688616510  1987 LEQQIK 1992
Cdd:TIGR02168  977 LENKIK 982
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 87-876 1.16e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 1.16e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    87 KVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQL 166
Cdd:TIGR02168  214 RYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   167 TRKNEQLQQDIEFYRKEAEQ---------RESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKN 237
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANlerqleeleAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   238 LEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvmaAVNAKVEEWKSVLSGKDL 317
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK------LEEAELKELQAELEELEE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   318 EILEYQQMIRDLREKLRTAQMDSDKsniiaLQQVIYELCGAVQERDNQIKMLSEQVEQYTTemernamLIEELKRPLKKD 397
Cdd:TIGR02168  448 ELEELQEELERLEEALEELREELEE-----AEQALDAAERELAQLQARLDSLERLQENLEG-------FSEGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   398 KGHSSDHQRRLEDLS--AKLQVAERKVLEAQRAAQLAE-----RDARDKDKElNDTLSRIRLYESGTDGLEAAISEIKEC 470
Cdd:TIGR02168  516 SGLSGILGVLSELISvdEGYEAAIEAALGGRLQAVVVEnlnaaKKAIAFLKQ-NELGRVTFLPLDSIKGTEIQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   471 KNQIRVRDREIEgMIKEINQLEMKINNLLDE---NEDLRERLGLNPKEE-------LDLSEFRRSKILKQRQYKAENQVL 540
Cdd:TIGR02168  595 KNIEGFLGVAKD-LVKFDPKLRKALSYLLGGvlvVDDLDNALELAKKLRpgyrivtLDGDLVRPGGVITGGSAKTNSSIL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   541 LKEIERLEEERLELKQRIRALVKDKGVTVVSNSLLDNSVEEKPVRSLRPSSGSTDDEIKRKNERLQKELSNKEKELELRR 620
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   621 SESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGvSIPSLERLVNALEMKYSEgkfdaslhLRTQVDQLTG 700
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE-ELKALREALDELRAELTL--------LNEEAANLRE 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   701 RNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMskstgssiphktlalpEEMTPTSAEAINALNEYTVQLLQE 780
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL----------------EELIEELESELEALLNERASLEEA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   781 IKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVDAVKIKEynhLLETLEK 860
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEA---LENKIED 965

                          810
                   ....*....|....*.
gi 688616510   861 DPSEIRREMAETGRKI 876
Cdd:TIGR02168  966 DEEEARRRLKRLENKI 981
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1781-2650 6.68e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 6.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1781 RDLNEELQLAKdgVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVEsdgpT 1860
Cdd:TIGR02168  216 KELKAELRELE--LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK----E 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1861 VDALQKKIRKLEHELDRKSisepaDKRSTLKEDKSSKEEVvrweegkkwqarvdkmrnvLKEKEREVDSQAKQLATMKEL 1940
Cdd:TIGR02168  290 LYALANEISRLEQQKQILR-----ERLANLERQLEELEAQ-------------------LEELESKLDELAEELAELEEK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1941 YSRLEQEKVSLQKKLKgrgvtadqvvgartlEADKEIEELHKRNAELEQQIKVMKQQQALPRdAAMEDITNRNRYLEERL 2020
Cdd:TIGR02168  346 LEELKEELESLEAELE---------------ELEAELEELESRLEELEEQLETLRSKVAQLE-LQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2021 YSMESRLSKeppsrpsdrhstspsqlswsskvrsmtfdvieaeqtqssllnstvvvTEKEISVIEDKATQTSFRSIDMGT 2100
Cdd:TIGR02168  410 ERLEDRRER-----------------------------------------------LQQEIEELLKKLEEAELKELQAEL 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2101 AEVNQDDENVAKNKIDLEQKAlmkddktEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELT 2180
Cdd:TIGR02168  443 EELEEELEELQEELERLEEAL-------EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2181 HREMMEKPLDEDQLEVENE-ETNAEEMLYSTMNQaeletpkVLLEGDEDYGQEPEELLKCECDPSAESKELDEEETALSN 2259
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGyEAAIEAALGGRLQA-------VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQG 588

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2260 STTFDAKLVSEQPAMEKNKSFTP---EAGFNPNLSEVSTSREL-NANTENDILGHLKAKVTRLNDKEHSMKSKARKTSGR 2335
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDpklRKALSYLLGGVLVVDDLdNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKT 668

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2336 GSDTPSQR----------------EHEFQKENLRLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKR 2399
Cdd:TIGR02168  669 NSSILERRreieeleekieeleekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2400 LNHLRGsgrsgktipELEKTIGLMKKVVEKVQRENENLKRTSE--VNVQEQLATLERDHEKLKSEYEKLKGKQEE----- 2472
Cdd:TIGR02168  749 IAQLSK---------ELTELEAEIEELEERLEEAEEELAEAEAeiEELEAQIEQLKEELKALREALDELRAELTLlneea 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2473 -QLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEEthqrlLLAQSKGATLLGVDSKT 2551
Cdd:TIGR02168  820 aNLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-----LLNERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2552 WKSSVvtrlfENKMKGLESDIAKKNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNVpveatTDEGLAREYQSVR 2631
Cdd:TIGR02168  895 ELEEL-----SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL-----TLEEAEALENKIE 964

                          890
                   ....*....|....*....
gi 688616510  2632 LANKQLEREKAQLLRQIQR 2650
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKE 983
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
995-1224 1.88e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  995 ERIDSINKELEISKEKLHTLEQAFEnisttggeiimdkatkavANSEIVSVSRRITTLEmkELNERQRAEHAQKMYEHLR 1074
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEPIRE------------------LAERYAAARERLAELE--YLRAALRLWFAQRRLELLE 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1075 NSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSvskhisdaDRKRITELEKTEANLRIEVSKLREVSDVAKM 1154
Cdd:COG4913   295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGN--------GGDRLEQLEREIERLERELEERERRRARLEA 366

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1155 QVSALDARQQSREKEVESLRRQVldyqaesdeKALIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQ 1224
Cdd:COG4913   367 LLAALGLPLPASAEEFAALRAEA---------AALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
 
Name Accession Description Interval E-value
CEP209_CC5 pfam16574
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ...
 1279-1406 9.47e-46

Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.


Pssm-ID: 465184 [Multi-domain]  Cd Length: 128  Bit Score: 161.78  E-value: 9.47e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1279 TMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQ 1358
Cdd:pfam16574    1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 688616510  1359 REEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLER 1406
Cdd:pfam16574   81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1125-1992 3.74e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.52  E-value: 3.74e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1125 RKRITE--LEKTEANLRievsklrEVSDVAKmqvsaldarqqSREKEVESLRRQVLDYQAESDEKALIAKLHQHIVALQL 1202
Cdd:TIGR02168  173 RRKETErkLERTRENLD-------RLEDILN-----------ELERQLKSLERQAEKAERYKELKAELRELELALLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1203 -SETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRrqfsgalplAQQEKFSNTML 1281
Cdd:TIGR02168  235 eELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA---------NEISRLEQQKQ 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1282 HLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQ--KVSEWHKKLEDVRLLEMRQSRELNTQR 1359
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeaELEELEAELEELESRLEELEEQLETLR 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1360 EEIKYLKNCVAEQERTISGLEEELVQqnnlLEERQLIWDQREVQLERQLDSYEKQ--QNEVLNTAQKFEEATGSLPDPNQ 1437
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLER----LEDRRERLQQEIEELLKKLEEAELKelQAELEELEEELEELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1438 planqldyALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLrlpAAAEREKLLADLSKQED 1517
Cdd:TIGR02168  462 --------ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK---NQSGLSGILGVLSELIS 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1518 SESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLgkarqEQEEIAKRHEEEVRALH----QKLDVYMDTSLDRFKQTAL 1593
Cdd:TIGR02168  531 VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFL-----KQNELGRVTFLPLDSIKgteiQGNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1594 ELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLE-----DKHAAQ 1668
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILErrreiEELEEK 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1669 MKGLSQEAEELRAQLIQMEKELHYLRTELEA--QKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTS 1746
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQlrKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1747 QAEQQIITNAAQKEEALNVQQivdkqtkelracvrdLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQ 1826
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEE---------------LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1827 SEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPAdkRSTLKEDKSSKEEVVRweeg 1906
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA--LALLRSELEELSEELR---- 904

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1907 kkwqarvdKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAE 1986
Cdd:TIGR02168  905 --------ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976


                   ....*.
gi 688616510  1987 LEQQIK 1992
Cdd:TIGR02168  977 LENKIK 982
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1207-1877 1.58e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 1.58e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1207 AISRLEATNTRLQKLEAqkLRDEqkLDEQQQALwhARQeghqrARhlrhtiQALR-RQFSGALPLAQQEKFSNTMLHLQE 1285
Cdd:COG1196   177 AERKLEATEENLERLED--ILGE--LERQLEPL--ERQ-----AE------KAERyRELKEELKELEAELLLLKLRELEA 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1286 DRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDakgaqkvsEWHKKLEDVRLLEMRQSRELNTQREEikyl 1365
Cdd:COG1196   240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL--------ELEEAQAEEYELLAELARLEQDIARL---- 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1366 kncvAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLpdpnqplANQLDY 1445
Cdd:COG1196   308 ----EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA-------EAELAE 376

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1446 ALGKIKEHVRTILETKTTCKILEEKLKEKEAAlwssEQNVLSRDKVINELRLRLPAAAEREKLLADLSKQEDSESQPTLK 1525
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQLEELEEA----EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1526 VAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEvRALHQKLDVYMDTSLDRFKQTALELIKKPTITVPT 1605
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL-LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1606 SKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAmeHAADMARLEDKHAAQMKGLSQEAEELRAQLIQ 1685
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL--PLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1686 MEKELHYLRTELEAQKEANVRspsntmknlverlknQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNV 1765
Cdd:COG1196   610 EADARYYVLGDTLLGRTLVAA---------------RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL 674

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1766 QQIVDKQTKELRACVRDLNEElqlakdgvRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQR 1845
Cdd:COG1196   675 LEAEAELEELAERLAEEELEL--------EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746

                         650       660       670
                  ....*....|....*....|....*....|..
gi 688616510 1846 LSSGLQAQVESDGPTVDALQKKIRKLEHELDR 1877
Cdd:COG1196   747 LLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 87-876 1.16e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 1.16e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    87 KVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQL 166
Cdd:TIGR02168  214 RYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   167 TRKNEQLQQDIEFYRKEAEQ---------RESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKN 237
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANlerqleeleAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   238 LEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvmaAVNAKVEEWKSVLSGKDL 317
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK------LEEAELKELQAELEELEE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   318 EILEYQQMIRDLREKLRTAQMDSDKsniiaLQQVIYELCGAVQERDNQIKMLSEQVEQYTTemernamLIEELKRPLKKD 397
Cdd:TIGR02168  448 ELEELQEELERLEEALEELREELEE-----AEQALDAAERELAQLQARLDSLERLQENLEG-------FSEGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   398 KGHSSDHQRRLEDLS--AKLQVAERKVLEAQRAAQLAE-----RDARDKDKElNDTLSRIRLYESGTDGLEAAISEIKEC 470
Cdd:TIGR02168  516 SGLSGILGVLSELISvdEGYEAAIEAALGGRLQAVVVEnlnaaKKAIAFLKQ-NELGRVTFLPLDSIKGTEIQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   471 KNQIRVRDREIEgMIKEINQLEMKINNLLDE---NEDLRERLGLNPKEE-------LDLSEFRRSKILKQRQYKAENQVL 540
Cdd:TIGR02168  595 KNIEGFLGVAKD-LVKFDPKLRKALSYLLGGvlvVDDLDNALELAKKLRpgyrivtLDGDLVRPGGVITGGSAKTNSSIL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   541 LKEIERLEEERLELKQRIRALVKDKGVTVVSNSLLDNSVEEKPVRSLRPSSGSTDDEIKRKNERLQKELSNKEKELELRR 620
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   621 SESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGvSIPSLERLVNALEMKYSEgkfdaslhLRTQVDQLTG 700
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE-ELKALREALDELRAELTL--------LNEEAANLRE 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   701 RNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMskstgssiphktlalpEEMTPTSAEAINALNEYTVQLLQE 780
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL----------------EELIEELESELEALLNERASLEEA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   781 IKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVDAVKIKEynhLLETLEK 860
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEA---LENKIED 965

                          810
                   ....*....|....*.
gi 688616510   861 DPSEIRREMAETGRKI 876
Cdd:TIGR02168  966 DEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 110-705 8.40e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 8.40e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  110 LRDEIRQLESHLERKEKEVTQLEK----EMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAE 185
Cdd:COG1196   191 LEDILGELERQLEPLERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  186 QRES--LQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTD 263
Cdd:COG1196   271 ELRLelEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  264 AIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvmaavnakVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQmdsdkS 343
Cdd:COG1196   351 EELEEAEAELAEAEEALLEAEAELAEAEEE-----------LEELAEELLEALRAAAELAAQLEELEEAEEALL-----E 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  344 NIIALQQVIYELCGAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKV- 422
Cdd:COG1196   415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLl 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  423 --LEAQRAAQLAERDARDKDKELNDTLSRIRLYESGTDGLE----AAISEIKECKNQIRVRDREIEGMIKEINQLEMKIN 496
Cdd:COG1196   495 llLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRA 574

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  497 NLLDENEDLRERLGLNPKEELDLSEFRRSKILKQRQYKAENQVLLKEIERLEEERLELKQRIRALVKDKGVTVVSnSLLD 576
Cdd:COG1196   575 TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREV-TLEG 653

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  577 NSVEEKPVRSLRpsSGSTDDEIKRKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQK 656
Cdd:COG1196   654 EGGSAGGSLTGG--SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 688616510  657 KTPTSTGVSIPSLERLVNALEMKYSEGKFDASlHLRTQVDQLTGRNEEL 705
Cdd:COG1196   732 AEREELLEELLEEEELLEEEALEELPEPPDLE-ELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1781-2650 6.68e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 6.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1781 RDLNEELQLAKdgVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVEsdgpT 1860
Cdd:TIGR02168  216 KELKAELRELE--LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK----E 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1861 VDALQKKIRKLEHELDRKSisepaDKRSTLKEDKSSKEEVvrweegkkwqarvdkmrnvLKEKEREVDSQAKQLATMKEL 1940
Cdd:TIGR02168  290 LYALANEISRLEQQKQILR-----ERLANLERQLEELEAQ-------------------LEELESKLDELAEELAELEEK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1941 YSRLEQEKVSLQKKLKgrgvtadqvvgartlEADKEIEELHKRNAELEQQIKVMKQQQALPRdAAMEDITNRNRYLEERL 2020
Cdd:TIGR02168  346 LEELKEELESLEAELE---------------ELEAELEELESRLEELEEQLETLRSKVAQLE-LQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2021 YSMESRLSKeppsrpsdrhstspsqlswsskvrsmtfdvieaeqtqssllnstvvvTEKEISVIEDKATQTSFRSIDMGT 2100
Cdd:TIGR02168  410 ERLEDRRER-----------------------------------------------LQQEIEELLKKLEEAELKELQAEL 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2101 AEVNQDDENVAKNKIDLEQKAlmkddktEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELT 2180
Cdd:TIGR02168  443 EELEEELEELQEELERLEEAL-------EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2181 HREMMEKPLDEDQLEVENE-ETNAEEMLYSTMNQaeletpkVLLEGDEDYGQEPEELLKCECDPSAESKELDEEETALSN 2259
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGyEAAIEAALGGRLQA-------VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQG 588

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2260 STTFDAKLVSEQPAMEKNKSFTP---EAGFNPNLSEVSTSREL-NANTENDILGHLKAKVTRLNDKEHSMKSKARKTSGR 2335
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDpklRKALSYLLGGVLVVDDLdNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKT 668

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2336 GSDTPSQR----------------EHEFQKENLRLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKR 2399
Cdd:TIGR02168  669 NSSILERRreieeleekieeleekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2400 LNHLRGsgrsgktipELEKTIGLMKKVVEKVQRENENLKRTSE--VNVQEQLATLERDHEKLKSEYEKLKGKQEE----- 2472
Cdd:TIGR02168  749 IAQLSK---------ELTELEAEIEELEERLEEAEEELAEAEAeiEELEAQIEQLKEELKALREALDELRAELTLlneea 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2473 -QLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEEthqrlLLAQSKGATLLGVDSKT 2551
Cdd:TIGR02168  820 aNLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-----LLNERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2552 WKSSVvtrlfENKMKGLESDIAKKNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNVpveatTDEGLAREYQSVR 2631
Cdd:TIGR02168  895 ELEEL-----SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL-----TLEEAEALENKIE 964

                          890
                   ....*....|....*....
gi 688616510  2632 LANKQLEREKAQLLRQIQR 2650
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 694-1410 1.49e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 1.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   694 QVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSKSTGSsIPHKTLALPEEMTPTSAEaINALNEY 773
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE-LQKELYALANEISRLEQQ-KQILRER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   774 TVQLLQEIKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVdavkikeynh 853
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ---------- 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   854 lLETLEKDPSEIRREMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQAAVTERIgylqrfkemaa 933
Cdd:TIGR02168  381 -LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE----------- 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   934 fkMASLQKSLDVSVpaSELERANKQYTELTIKYRNLLQKDNHLVQKTTSLEHLETENMSLRERIdsinKELEISKEKLH- 1012
Cdd:TIGR02168  449 --LEELQEELERLE--EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV----KALLKNQSGLSg 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1013 ---------TLEQAFEN-ISTTGGE----IIMDKATKAVANSE------------IVSVSRRITTLEMKELNERQRAEHA 1066
Cdd:TIGR02168  521 ilgvlseliSVDEGYEAaIEAALGGrlqaVVVENLNAAKKAIAflkqnelgrvtfLPLDSIKGTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1067 QKMYEHLRNSLKQV-----------------------------EERNFELE----------TKFAELTKLNLEAQRIE-R 1106
Cdd:TIGR02168  601 LGVAKDLVKFDPKLrkalsyllggvlvvddldnalelakklrpGYRIVTLDgdlvrpggviTGGSAKTNSSILERRREiE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1107 ELRDELADSVSKhiSDADRKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDE 1186
Cdd:TIGR02168  681 ELEEKIEELEEK--IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1187 KA---------------LIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRAR 1251
Cdd:TIGR02168  759 LEaeieeleerleeaeeELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1252 HLRHTIQALRRQfsgalpLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEgkaQELELKLKGLEELIATLKDAkgA 1331
Cdd:TIGR02168  839 RLEDLEEQIEEL------SEDIESLAAEIEELEELIEELESELEALLNERASLE---EALALLRSELEELSEELREL--E 907

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616510  1332 QKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTisgLEEELVQQNNLLEERQLIWDQREVQLERQLDS 1410
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL---TLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
PTZ00121 PTZ00121
MAEBL; Provisional
 975-1835 2.71e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  975 HLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKA------TKAVANSEIVSVSRR 1048
Cdd:PTZ00121  993 HILQKPTCVIDKENHFSFTALTANTIDFNQNFNIEKIEELTEYGNNDDVLKEKDIIDEDidgnheGKAEAKAHVGQDEGL 1072

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1049 ITTLEMKELN--ERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSVSKHISDADRK 1126
Cdd:PTZ00121 1073 KPSYKDFDFDakEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAK 1152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1127 RITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALIAKLHQHivALQLSETT 1206
Cdd:PTZ00121 1153 RVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAED--AKKAEAVK 1230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1207 AISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQ---ALRRQFSGALPLAQQEKFSNTMLHL 1283
Cdd:PTZ00121 1231 KAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADElkkAEEKKKADEAKKAEEKKKADEAKKK 1310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1284 QEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLE-MRQSRELNTQREEI 1362
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEaKKKADAAKKKAEEK 1390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1363 KYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLPDPNQPLANQ 1442
Cdd:PTZ00121 1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1443 LDYALGKIKEHVRTILETKTTC----KILEEKLKEKEAALWSSEQNVLSRDKVINELRlrlpaAAEREKLLADLSKQEDS 1518
Cdd:PTZ00121 1471 KADEAKKKAEEAKKADEAKKKAeeakKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-----KAEEAKKADEAKKAEEK 1545

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1519 ESQPTLKVAHQtinnlqgrLDQKEEVLKKYQnllGKARQEQEEIAKRHEEEVRALHQKLDVYMDTSLDRFKQTALELIKK 1598
Cdd:PTZ00121 1546 KKADELKKAEE--------LKKAEEKKKAEE---AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK 1614

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1599 PTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLED-KHAAQMKGLSQEAE 1677
Cdd:PTZ00121 1615 AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEaKKAEEDEKKAAEAL 1694

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1678 ELRAQLIQMEKELHYLRTElEAQKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAA 1757
Cdd:PTZ00121 1695 KKEAEEAKKAEELKKKEAE-EKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1758 QKEEALNVQQIVDKQTKELRACV----RDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQnklQSEKEALE 1833
Cdd:PTZ00121 1774 RKEKEAVIEEELDEEDEKRRMEVdkkiKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQ---LEEADAFE 1850


                  ..
gi 688616510 1834 EH 1835
Cdd:PTZ00121 1851 KH 1852
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1351-1884 2.61e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.20  E-value: 2.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1351 QSRELNTQREEIK-YLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEAT 1429
Cdd:pfam15921  293 QANSIQSQLEIIQeQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQES 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1430 GSLPDPNQPLANQL--------------------DYALGKIKEHVRTILETKTT-CKILEEKLKEKEAALWSSEQNVLSR 1488
Cdd:pfam15921  373 GNLDDQLQKLLADLhkrekelslekeqnkrlwdrDTGNSITIDHLRRELDDRNMeVQRLEALLKAMKSECQGQMERQMAA 452

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1489 DKVINELRLR---LPAAAEREKLLADLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKAR-------QE 1558
Cdd:pfam15921  453 IQGKNESLEKvssLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRsrvdlklQE 532

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1559 QEEIaKRHEEEVRALHQKLDVYMDTSLDRFKQTALELIKKPTITVPTSKH-------LVRLAEMEQTVAEQDNSLsslsQ 1631
Cdd:pfam15921  533 LQHL-KNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHgrtagamQVEKAQLEKEINDRRLEL----Q 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1632 KLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQM---KGLSQEAEELRAQLIQMEKELHYLRTELEAQKEaNVRSP 1708
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR-NFRNK 686

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1709 SNTMKNLVERLKNQLALKEKQLKalskallelraeltsQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQ 1788
Cdd:pfam15921  687 SEEMETTTNKLKMQLKSAQSELE---------------QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQ 751

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1789 LAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKI 1868
Cdd:pfam15921  752 FLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQE 831

                          570       580
                   ....*....|....*....|.
gi 688616510  1869 R-----KLEHELDRKSISEPA 1884
Cdd:pfam15921  832 QesvrlKLQHTLDVKELQGPG 852
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 57-536 2.91e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.20  E-value: 2.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    57 RMKLDEIKCAYEVVDsagaEQARIENELKAKVLkleSELEMAQRVMgggdKHFLRDEIRQLESHLERKEKEVTQLEKEMG 136
Cdd:pfam15921  291 RSQANSIQSQLEIIQ----EQARNQNSMYMRQL---SDLESTVSQL----RSELREAKRMYEDKIEELEKQLVLANSELT 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   137 KERKSNEELalrAEEAEEKNRKLKREIKQLTRKNEQLQQdiefyrkEAEQRESLQTKEESNEIQrrLTKANQQLYQCMEE 216
Cdd:pfam15921  360 EARTERDQF---SQESGNLDDQLQKLLADLHKREKELSL-------EKEQNKRLWDRDTGNSIT--IDHLRRELDDRNME 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   217 LQHAEDMAANLRSEnehLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRK--DRDHAKLQVRELTDQ----IQAR 290
Cdd:pfam15921  428 VQRLEALLKAMKSE---CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKvvEELTAKKMTLESSERtvsdLTAS 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   291 VEEDDPVMAAVNAKVEEWKSVLsgkDLEILEYQQMiRDLREKLRTAQMDSDKsniIALQqviyelcgaVQERDNQIKMLS 370
Cdd:pfam15921  505 LQEKERAIEATNAEITKLRSRV---DLKLQELQHL-KNEGDHLRNVQTECEA---LKLQ---------MAEKDKVIEILR 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   371 EQVE---QYTTEMERNAMLIEELKRPLKKDKghssdHQRRLEdlsaklqVAERKVLEAQRAAQLAERDARDKDKElndtL 447
Cdd:pfam15921  569 QQIEnmtQLVGQHGRTAGAMQVEKAQLEKEI-----NDRRLE-------LQEFKILKDKKDAKIRELEARVSDLE----L 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   448 SRIRLYESGTDGLEaAISEIKECKNQirvrdreiegMIKEINQLEMKINNLLDENEDLRERLgLNPKEELDLSEFRRSKI 527
Cdd:pfam15921  633 EKVKLVNAGSERLR-AVKDIKQERDQ----------LLNEVKTSRNELNSLSEDYEVLKRNF-RNKSEEMETTTNKLKMQ 700


                   ....*....
gi 688616510   528 LKQRQYKAE 536
Cdd:pfam15921  701 LKSAQSELE 709
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
126-742 1.47e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 1.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  126 KEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESlqTKEESNEIQRRLTK 205
Cdd:PRK03918  172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE--LKEEIEELEKELES 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  206 ANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEEsVKEMEKMTDEYNKMKiavqqtdAIMDQLRKDRDHAKLQVRELTD 285
Cdd:PRK03918  250 LEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE-LKELKEKAEEYIKLS-------EFYEEYLDELREIEKRLSRLEE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  286 QIQArVEEDDPVMAAVNAKVEEWKSVLSG--KDLEILE-YQQMIRDLREKLRTAQMDSDKSNIIALQQVIYELcgavqer 362
Cdd:PRK03918  322 EING-IEERIKELEEKEERLEELKKKLKEleKRLEELEeRHELYEEAKAKKEELERLKKRLTGLTPEKLEKEL------- 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  363 dnqikmlsEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDKDke 442
Cdd:PRK03918  394 --------EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKR-- 463

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  443 lndtlsrirlyesgtdgLEAAISEIKECKNQIRVRDREIEGMIKEINQLeMKINNLLDENEDLRERLGLNPKEELDlSEF 522
Cdd:PRK03918  464 -----------------IEKELKEIEEKERKLRKELRELEKVLKKESEL-IKLKELAEQLKELEEKLKKYNLEELE-KKA 524

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  523 RRSKILKQRQYKAENQVllKEIERLEEERLELKQRIRALVKDKGvtvvsnslldnSVEEKPVRSLRPSSGSTDDEIKRKN 602
Cdd:PRK03918  525 EEYEKLKEKLIKLKGEI--KSLKKELEKLEELKKKLAELEKKLD-----------ELEEELAELLKELEELGFESVEELE 591

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  603 ERLQKELSNKEKELELRRSEStqfkaKLNEMLNENKQLEQGMKEILQAIQDTQKKtptstgvsIPSLERLVNALEMKYSE 682
Cdd:PRK03918  592 ERLKELEPFYNEYLELKDAEK-----ELEREEKELKKLEEELDKAFEELAETEKR--------LEELRKELEELEKKYSE 658

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  683 GKFDASLHLRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSK 742
Cdd:PRK03918  659 EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEK 718
PTZ00121 PTZ00121
MAEBL; Provisional
 1765-2533 1.95e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 1.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1765 VQQIVDKQTKELRACVRDLNEElqlAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHlnelKKKIQ 1844
Cdd:PTZ00121 1029 IEELTEYGNNDDVLKEKDIIDE---DIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEA----FGKAE 1101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1845 RLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSisepadkrstlkEDKSSKEEVVRWEEGKkwqaRVDKMRNVLKEKE 1924
Cdd:PTZ00121 1102 EAKKTETGKAEEARKAEEAKKKAEDARKAEEARKA------------EDARKAEEARKAEDAK----RVEIARKAEDARK 1165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1925 REVDSQAKQLATMKELYSRLEQEKVSLQKKLKgrgvTADQVVGARTLEADKEIEELhkRNAELEQQIKVMKQQQALPRDA 2004
Cdd:PTZ00121 1166 AEEARKAEDAKKAEAARKAEEVRKAEELRKAE----DARKAEAARKAEEERKAEEA--RKAEDAKKAEAVKKAEEAKKDA 1239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2005 AMEDITNRNRYLEERLYSMESRLSKEPPSRPSDR--HSTSPSQLSWSSKVRSMTfDVIEAEQTQSSLLNSTVVVTEKEIS 2082
Cdd:PTZ00121 1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKaeEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKAD 1318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2083 VIEDKATQTSFRSidmgtAEVNQDDENVAKNKIDLEQKALMKDDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYA 2162
Cdd:PTZ00121 1319 EAKKKAEEAKKKA-----DAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2163 QEELKTNDEAEELESELTHREMMEKPLDEDQLEVEnEETNAEEMlystMNQAELETPKVLLEGDEDYGQEPEELLKcecd 2242
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE-EKKKADEA----KKKAEEAKKADEAKKKAEEAKKAEEAKK---- 1464

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2243 PSAESKELDEEETALSNSTTFDAKLVSEQPAMEKNKSFTPEAGFNPNLSEVSTSRELNANTENDilghlKAKVTRLNDKE 2322
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-----KAEEAKKADEA 1539

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2323 HSMKSKARKTSGRGSDTPSQREHEFQKENLRLSTENLELRFQLEQANKDLPrlKDQVSDLKEMCSVLKKEKAEVEKRLNH 2402
Cdd:PTZ00121 1540 KKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE--EARIEEVMKLYEEEKKMKAEEAKKAEE 1617

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2403 LRGSGRsgktipELEKTIGLMKKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKG---KQEEQLNSRLE 2479
Cdd:PTZ00121 1618 AKIKAE------ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAeeaKKAEEDEKKAA 1691

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....
gi 688616510 2480 SKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEETHQR 2533
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1969-2727 9.71e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 9.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1969 RTLEADKEIEELHKRNAELEQQIKVMKQQQALPRDAAMEDITNRNRYLEERLYSMESRLSKEPPSRPSDRHSTSPSQLSW 2048
Cdd:pfam02463  185 LAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2049 SSKVRSMTFDVIEAEQTQSSLLNSTVVVTEKEISVIE----DKATQTSFRSIDMGTAEVNQDDENVAKNKIDLEQKALMK 2124
Cdd:pfam02463  265 EKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllklERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2125 DDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELTHREMMEKpLDEDQLEVENEETNAE 2204
Cdd:pfam02463  345 KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEA-QLLLELARQLEDLLKE 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2205 EMLYSTMNQAELETPKVLLEGDEDYGQEPEELL---KCECDPSAESKELDEEETALSNSTTFDAKLVSEQPAMEKNKSFT 2281
Cdd:pfam02463  424 EKKEELEILEEEEESIELKQGKLTEEKEELEKQelkLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2282 P-EAGFNPNLSEVSTSRELNANTENDILGHLKAKVTRLNDKEHSMKSKARKTSGRGSDTPSQREHEFQKENLRLSTENLE 2360
Cdd:pfam02463  504 KaRSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLL 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2361 LRFQLEQANKDLP---------RLKDQVSDLKEMCSVLKKEKAEVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQ 2431
Cdd:pfam02463  584 IPKLKLPLKSIAVleidpilnlAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSE 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2432 RENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKGKQEEQLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRV 2511
Cdd:pfam02463  664 VKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQ 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2512 AKASLEVANEKLKAELEETHQRLLLAQSKGATLLGVDSKTWKSSVVTRLFENKMKGLESDIAKKNISISELKVQLKEANE 2591
Cdd:pfam02463  744 KIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLL 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2592 KLQATQHTVIQLKEQVELLKNVPVEATTDEGLAREYQSVRLANKQLEREKAQLLRQIQRNEVQLGTNKDGPGYTELQE-- 2669
Cdd:pfam02463  824 IEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEle 903

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 688616510  2670 ---QIKAANNEKKKLQDEVRKLTQELKHFDPTFFEELEDLKFNYNLEVKKNIVLEEQLKKL 2727
Cdd:pfam02463  904 eesQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2391-2510 3.38e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 46.00  E-value: 3.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2391 KEKAEVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQRENENLKRtsevnvqeQLATLERDHEKLKSEYEKLKGKQ 2470
Cdd:COG2433   386 IEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEA--------ELEEKDERIERLERELSEARSEE 457

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 688616510 2471 EEQLNSRLEsktkgIEKIMMENERLRKEIKKEAEAAEKLR 2510
Cdd:COG2433   458 RREIRKDRE-----ISRLDREIERLERELEEERERIEELK 492
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1208-1386 7.78e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 7.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1208 ISRLEATNTRLQKLEAQ--KLRDEQKLDEQQQALWHARQEGH---QRARHLRHTIQALRRQfsgalpLAQQEKFSNTMLH 1282
Cdd:COG4913   616 EAELAELEEELAEAEERleALEAELDALQERREALQRLAEYSwdeIDVASAEREIAELEAE------LERLDASSDDLAA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1283 LQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGA--QKVSEWHKKLEDVRLLEMRQSRELNTQRE 1360
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaeDLARLELRALLEERFAAALGDAVERELRE 769

                         170       180
                  ....*....|....*....|....*.
gi 688616510 1361 EikyLKNCVAEQERTISGLEEELVQQ 1386
Cdd:COG4913   770 N---LEERIDALRARLNRAEEELERA 792
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
995-1224 1.88e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  995 ERIDSINKELEISKEKLHTLEQAFEnisttggeiimdkatkavANSEIVSVSRRITTLEmkELNERQRAEHAQKMYEHLR 1074
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEPIRE------------------LAERYAAARERLAELE--YLRAALRLWFAQRRLELLE 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1075 NSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSvskhisdaDRKRITELEKTEANLRIEVSKLREVSDVAKM 1154
Cdd:COG4913   295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGN--------GGDRLEQLEREIERLERELEERERRRARLEA 366

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1155 QVSALDARQQSREKEVESLRRQVldyqaesdeKALIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQ 1224
Cdd:COG4913   367 LLAALGLPLPASAEEFAALRAEA---------AALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
PRK12704 PRK12704
phosphodiesterase; Provisional
 1295-1430 9.83e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 9.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1295 QITEEERRKAEGKAQELELKLKgleeliatlkdakgaqkvSEWHKKLEDVRllemrqsRELNTQREEIKYLKNCVAEQER 1374
Cdd:PRK12704   42 RILEEAKKEAEAIKKEALLEAK------------------EEIHKLRNEFE-------KELRERRNELQKLEKRLLQKEE 96

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 688616510 1375 TISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLntaQKFEEATG 1430
Cdd:PRK12704   97 NLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQL---QELERISG 149
 
Name Accession Description Interval E-value
CEP209_CC5 pfam16574
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ...
 1279-1406 9.47e-46

Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.


Pssm-ID: 465184 [Multi-domain]  Cd Length: 128  Bit Score: 161.78  E-value: 9.47e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1279 TMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQ 1358
Cdd:pfam16574    1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 688616510  1359 REEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLER 1406
Cdd:pfam16574   81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1125-1992 3.74e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.52  E-value: 3.74e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1125 RKRITE--LEKTEANLRievsklrEVSDVAKmqvsaldarqqSREKEVESLRRQVLDYQAESDEKALIAKLHQHIVALQL 1202
Cdd:TIGR02168  173 RRKETErkLERTRENLD-------RLEDILN-----------ELERQLKSLERQAEKAERYKELKAELRELELALLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1203 -SETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRrqfsgalplAQQEKFSNTML 1281
Cdd:TIGR02168  235 eELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA---------NEISRLEQQKQ 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1282 HLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQ--KVSEWHKKLEDVRLLEMRQSRELNTQR 1359
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeaELEELEAELEELESRLEELEEQLETLR 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1360 EEIKYLKNCVAEQERTISGLEEELVQqnnlLEERQLIWDQREVQLERQLDSYEKQ--QNEVLNTAQKFEEATGSLPDPNQ 1437
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLER----LEDRRERLQQEIEELLKKLEEAELKelQAELEELEEELEELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1438 planqldyALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLrlpAAAEREKLLADLSKQED 1517
Cdd:TIGR02168  462 --------ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK---NQSGLSGILGVLSELIS 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1518 SESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLgkarqEQEEIAKRHEEEVRALH----QKLDVYMDTSLDRFKQTAL 1593
Cdd:TIGR02168  531 VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFL-----KQNELGRVTFLPLDSIKgteiQGNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1594 ELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLE-----DKHAAQ 1668
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILErrreiEELEEK 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1669 MKGLSQEAEELRAQLIQMEKELHYLRTELEA--QKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTS 1746
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQlrKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1747 QAEQQIITNAAQKEEALNVQQivdkqtkelracvrdLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQ 1826
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEE---------------LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1827 SEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPAdkRSTLKEDKSSKEEVVRweeg 1906
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA--LALLRSELEELSEELR---- 904

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1907 kkwqarvdKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAE 1986
Cdd:TIGR02168  905 --------ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976


                   ....*.
gi 688616510  1987 LEQQIK 1992
Cdd:TIGR02168  977 LENKIK 982
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1060-1846 4.31e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 4.31e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1060 RQRAEHAQKMYEHLRNSLKQVEERNFELETKfaeLTKLNLEAQRIER--ELRDELaDSVSKHISDAD----RKRITELEK 1133
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLEDILNELERQ---LKSLERQAEKAERykELKAEL-RELELALLVLRleelREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1134 TEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAEsdekalIAKLHQHIVALQLSETTAISRLEA 1213
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE------ISRLEQQKQILRERLANLERQLEE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1214 TNTRLQKLEAQKLRDEQKLDEQQQALWHARQEgHQRARHLRHTIQALRRQFSGALPLAQQEkfsntMLHLQEDRARVRED 1293
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEE-LESLEAELEELEAELEELESRLEELEEQ-----LETLRSKVAQLELQ 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1294 AQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQE 1373
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1374 RTISGLEEELVQQNNLLEERQliwdqrevQLERQLDSYEKQQNEVLNTAQKFEEATGSLPD---PNQPLANQLDYALGKI 1450
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLE--------RLQENLEGFSEGVKALLKNQSGLSGILGVLSElisVDEGYEAAIEAALGGR 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1451 KEHVrtILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLPAAAEREKLLADLSKQEDSESQPTL------ 1524
Cdd:TIGR02168  547 LQAV--VVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALsyllgg 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1525 -KVAH--QTINNLQGRLDQKE------------------EVLKKYQNLLGKARQ--EQEEIAKRHEEEVRALHQKLDVY- 1580
Cdd:TIGR02168  625 vLVVDdlDNALELAKKLRPGYrivtldgdlvrpggvitgGSAKTNSSILERRREieELEEKIEELEEKIAELEKALAELr 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1581 --MDTSLDRFKQTALELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADM 1658
Cdd:TIGR02168  705 keLEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1659 ARLEdkhaAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKE--ANVRSPSNTMKNLVERLKNQLALKEKQLKALSKA 1736
Cdd:TIGR02168  785 EELE----AQIEQLKEELKALREALDELRAELTLLNEEAANLRErlESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1737 LLELRAELT-SQAEQQIITNA-AQKEEALNV----QQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLET 1810
Cdd:TIGR02168  861 IEELEELIEeLESELEALLNErASLEEALALlrseLEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 688616510  1811 LNK--------DLQRSQKSQNKLQSEKEALEEHLNELKKKIQRL 1846
Cdd:TIGR02168  941 LQErlseeyslTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1207-1877 1.58e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 1.58e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1207 AISRLEATNTRLQKLEAqkLRDEqkLDEQQQALwhARQeghqrARhlrhtiQALR-RQFSGALPLAQQEKFSNTMLHLQE 1285
Cdd:COG1196   177 AERKLEATEENLERLED--ILGE--LERQLEPL--ERQ-----AE------KAERyRELKEELKELEAELLLLKLRELEA 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1286 DRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDakgaqkvsEWHKKLEDVRLLEMRQSRELNTQREEikyl 1365
Cdd:COG1196   240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL--------ELEEAQAEEYELLAELARLEQDIARL---- 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1366 kncvAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLpdpnqplANQLDY 1445
Cdd:COG1196   308 ----EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA-------EAELAE 376

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1446 ALGKIKEHVRTILETKTTCKILEEKLKEKEAAlwssEQNVLSRDKVINELRLRLPAAAEREKLLADLSKQEDSESQPTLK 1525
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQLEELEEA----EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1526 VAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEvRALHQKLDVYMDTSLDRFKQTALELIKKPTITVPT 1605
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL-LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1606 SKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAmeHAADMARLEDKHAAQMKGLSQEAEELRAQLIQ 1685
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL--PLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1686 MEKELHYLRTELEAQKEANVRspsntmknlverlknQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNV 1765
Cdd:COG1196   610 EADARYYVLGDTLLGRTLVAA---------------RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL 674

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1766 QQIVDKQTKELRACVRDLNEElqlakdgvRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQR 1845
Cdd:COG1196   675 LEAEAELEELAERLAEEELEL--------EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746

                         650       660       670
                  ....*....|....*....|....*....|..
gi 688616510 1846 LSSGLQAQVESDGPTVDALQKKIRKLEHELDR 1877
Cdd:COG1196   747 LLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1656-2205 2.23e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.05  E-value: 2.23e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1656 ADMARLEDKHA---AQMKGLSQEAE------ELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKNLVERLKNQLALK 1726
Cdd:COG1196   186 ENLERLEDILGeleRQLEPLERQAEkaeryrELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAEL 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1727 EKQLKALSKALLELRAELTS--QAEQQIITNAAQKEEALNVQQI----VDKQTKELRACVRDLNEELQLAKDGVRAAKAR 1800
Cdd:COG1196   266 EAELEELRLELEELELELEEaqAEEYELLAELARLEQDIARLEErrreLEERLEELEEELAELEEELEELEEELEELEEE 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1801 ENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSI 1880
Cdd:COG1196   346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1881 SEPADKRSTLKEDKSSKEEVVRWEEGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGV 1960
Cdd:COG1196   426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1961 TADQVVGARTLEADKEIEElhkrnaELEQQIKVMKQQQALPRDAAMEDITNRNRYLEERLYSMESRLSKEPPSR------ 2034
Cdd:COG1196   506 FLEGVKAALLLAGLRGLAG------AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRatflpl 579

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2035 ----PSDRHSTSPSQLSWSSKVRSMTFDVIEAEQTQSSLLNSTVVVT------EKEISVIEDKATQTSFRSIDMGTAEVN 2104
Cdd:COG1196   580 dkirARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTlvaarlEAALRRAVTLAGRLREVTLEGEGGSAG 659

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2105 QDDENVAKNKIDLEQKALMKDDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELTHREM 2184
Cdd:COG1196   660 GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE 739

                         570       580
                  ....*....|....*....|.
gi 688616510 2185 MEKPLDEDQLEVENEETNAEE 2205
Cdd:COG1196   740 ELLEEEELLEEEALEELPEPP 760
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 87-876 1.16e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 1.16e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    87 KVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQL 166
Cdd:TIGR02168  214 RYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   167 TRKNEQLQQDIEFYRKEAEQ---------RESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKN 237
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANlerqleeleAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   238 LEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvmaAVNAKVEEWKSVLSGKDL 317
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK------LEEAELKELQAELEELEE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   318 EILEYQQMIRDLREKLRTAQMDSDKsniiaLQQVIYELCGAVQERDNQIKMLSEQVEQYTTemernamLIEELKRPLKKD 397
Cdd:TIGR02168  448 ELEELQEELERLEEALEELREELEE-----AEQALDAAERELAQLQARLDSLERLQENLEG-------FSEGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   398 KGHSSDHQRRLEDLS--AKLQVAERKVLEAQRAAQLAE-----RDARDKDKElNDTLSRIRLYESGTDGLEAAISEIKEC 470
Cdd:TIGR02168  516 SGLSGILGVLSELISvdEGYEAAIEAALGGRLQAVVVEnlnaaKKAIAFLKQ-NELGRVTFLPLDSIKGTEIQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   471 KNQIRVRDREIEgMIKEINQLEMKINNLLDE---NEDLRERLGLNPKEE-------LDLSEFRRSKILKQRQYKAENQVL 540
Cdd:TIGR02168  595 KNIEGFLGVAKD-LVKFDPKLRKALSYLLGGvlvVDDLDNALELAKKLRpgyrivtLDGDLVRPGGVITGGSAKTNSSIL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   541 LKEIERLEEERLELKQRIRALVKDKGVTVVSNSLLDNSVEEKPVRSLRPSSGSTDDEIKRKNERLQKELSNKEKELELRR 620
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   621 SESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGvSIPSLERLVNALEMKYSEgkfdaslhLRTQVDQLTG 700
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE-ELKALREALDELRAELTL--------LNEEAANLRE 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   701 RNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMskstgssiphktlalpEEMTPTSAEAINALNEYTVQLLQE 780
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL----------------EELIEELESELEALLNERASLEEA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   781 IKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVDAVKIKEynhLLETLEK 860
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEA---LENKIED 965

                          810
                   ....*....|....*.
gi 688616510   861 DPSEIRREMAETGRKI 876
Cdd:TIGR02168  966 DEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 407-1325 1.86e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.86e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   407 RLEDLSAKLqvaERKVLEAQRAAQLAERDardkdKELNDTLSRIRLYESGTDgLEAAISEIKECKNQIRVRDREIEGMIK 486
Cdd:TIGR02168  190 RLEDILNEL---ERQLKSLERQAEKAERY-----KELKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   487 EINQLEMKINNLLDENEDLRERLGLNPKEELDLSefrrskilkqrqykaenqvllkeierleeerlelkQRIRALVKDKG 566
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALA-----------------------------------NEISRLEQQKQ 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   567 VTVVSNSLLDNSVEEKPVRSlrpssgstdDEIKRKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKE 646
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQL---------EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   647 ilqaiqdtqkktptstgvsipsLERLVNALEMKYSEgkfdaslhLRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKA 726
Cdd:TIGR02168  377 ----------------------LEEQLETLRSKVAQ--------LELQIASLNNEIERLEARLERLEDRRERLQQEIEEL 426

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   727 NEKIARLESEMESMskstgssiphkTLALPEEMTPTSAEAINALNEYTVQLLQEIKNKGDSIEQLGSALEEYKRKFAVIR 806
Cdd:TIGR02168  427 LKKLEEAELKELQA-----------ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   807 HQQGLLYKEHQSERESWqKERDSFAELKSKLEEQREVDAvkikEYNHLLET-LEKDPSEIRREMAETGRKIVVLRVNEKC 885
Cdd:TIGR02168  496 RLQENLEGFSEGVKALL-KNQSGLSGILGVLSELISVDE----GYEAAIEAaLGGRLQAVVVENLNAAKKAIAFLKQNEL 570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   886 LTRrytTLLELEqhlRKENAKLKEDFTQMQAAVTERIGYLQRFKEMAAFKMASLQKSLDVSVPASELERANKQYTELTIK 965
Cdd:TIGR02168  571 GRV---TFLPLD---SIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPG 644

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   966 YRnLLQKDNHLV-----------QKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENIsttggeiimdKAT 1034
Cdd:TIGR02168  645 YR-IVTLDGDLVrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEEL----------EEE 713

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1035 KAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELEtkfAELTKLNLEAQRIERElRDELAD 1114
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE---ERLEEAEEELAEAEAE-IEELEA 789

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1115 SVSKHISDAD--RKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAE-SDEKALIA 1191
Cdd:TIGR02168  790 QIEQLKEELKalREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEiEELEELIE 869

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1192 KLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALwharqeghQRARHLRHTIQalrrqfsgalplA 1271
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRREL--------EELREKLAQLE------------L 929

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 688616510  1272 QQEKFSNTMLHLQEdraRVREDAQITEEE----RRKAEGKAQELELKLKGLEELIATL 1325
Cdd:TIGR02168  930 RLEGLEVRIDNLQE---RLSEEYSLTLEEaealENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 110-705 8.40e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 8.40e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  110 LRDEIRQLESHLERKEKEVTQLEK----EMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAE 185
Cdd:COG1196   191 LEDILGELERQLEPLERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  186 QRES--LQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTD 263
Cdd:COG1196   271 ELRLelEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  264 AIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvmaavnakVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQmdsdkS 343
Cdd:COG1196   351 EELEEAEAELAEAEEALLEAEAELAEAEEE-----------LEELAEELLEALRAAAELAAQLEELEEAEEALL-----E 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  344 NIIALQQVIYELCGAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKV- 422
Cdd:COG1196   415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLl 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  423 --LEAQRAAQLAERDARDKDKELNDTLSRIRLYESGTDGLE----AAISEIKECKNQIRVRDREIEGMIKEINQLEMKIN 496
Cdd:COG1196   495 llLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRA 574

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  497 NLLDENEDLRERLGLNPKEELDLSEFRRSKILKQRQYKAENQVLLKEIERLEEERLELKQRIRALVKDKGVTVVSnSLLD 576
Cdd:COG1196   575 TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREV-TLEG 653

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  577 NSVEEKPVRSLRpsSGSTDDEIKRKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQK 656
Cdd:COG1196   654 EGGSAGGSLTGG--SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 688616510  657 KTPTSTGVSIPSLERLVNALEMKYSEGKFDASlHLRTQVDQLTGRNEEL 705
Cdd:COG1196   732 AEREELLEELLEEEELLEEEALEELPEPPDLE-ELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 951-1568 2.42e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 2.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  951 ELERANKQYTELTIKYRNLLQKdnhLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAfenISTTGGEIIM 1030
Cdd:COG1196   240 ELEELEAELEELEAELEELEAE---LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQD---IARLEERRRE 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1031 DKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRD 1110
Cdd:COG1196   314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1111 ELAdsvskhisdADRKRITELEKTEANLRIEVSKLREvsdvakMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALI 1190
Cdd:COG1196   394 AAA---------ELAAQLEELEEAEEALLERLERLEE------ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1191 AKLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRRQFSGALPL 1270
Cdd:COG1196   459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1271 AQQEKFSNTMLHLQEDRARVREDAQitEEERRKAEGKAQELELklkgleeliATLKDAKGAQKVSEWHKKLEDVRLLEMR 1350
Cdd:COG1196   539 ALEAALAAALQNIVVEDDEVAAAAI--EYLKAAKAGRATFLPL---------DKIRARAALAAALARGAIGAAVDLVASD 607

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1351 QSRELNTQREEIKYLKNCVAEQERTISGLEeelvqqnnllEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATg 1430
Cdd:COG1196   608 LREADARYYVLGDTLLGRTLVAARLEAALR----------RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE- 676

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1431 slpdpnqpLANQLDYALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLPAAAEREKLLA 1510
Cdd:COG1196   677 --------AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 688616510 1511 DLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVlkkyqNLLgkARQEQEEIAKRHEE 1568
Cdd:COG1196   749 EEEALEELPEPPDLEELERELERLEREIEALGPV-----NLL--AIEEYEELEERYDF 799
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 788-1568 5.60e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 5.60e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   788 IEQLGSALEEYKRKFAVIRHQ--QGLLYKEHQSERESWQK-----ERDSFAELKSKLEEQREVDAVKIKEYNHLLETLEK 860
Cdd:TIGR02168  188 LDRLEDILNELERQLKSLERQaeKAERYKELKAELRELELallvlRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   861 DPSEIRREMAETGRKIVVLrvnEKCLTRRYTTLLELEQHLRKENAKLKEDFTQmQAAVTERIGYLQRFKEMAAFKMASLQ 940
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEEL---QKELYALANEISRLEQQKQILRERLANLERQ-LEELEAQLEELESKLDELAEELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   941 KSLDVSvpASELERANKQYTELTIKYRNLLQKdnhLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFEN 1020
Cdd:TIGR02168  344 EKLEEL--KEELESLEAELEELEAELEELESR---LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1021 ISTTGGEiimdkATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLE 1100
Cdd:TIGR02168  419 LQQEIEE-----LLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1101 AQRIERELRDELADSV----SKHISDADRKRITELEKTEANLRIEVSK-LRE-----VSDVAKMQVSALDARQQSR---- 1166
Cdd:TIGR02168  494 LERLQENLEGFSEGVKallkNQSGLSGILGVLSELISVDEGYEAAIEAaLGGrlqavVVENLNAAKKAIAFLKQNElgrv 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1167 ---------EKEVESLRRQV-------------LDYQAESDEKALIAKLHQHIVALQLSETTAISRLE------------ 1212
Cdd:TIGR02168  574 tflpldsikGTEIQGNDREIlkniegflgvakdLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLrpgyrivtldgd 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1213 --------------------ATNTRLQKLEAQKLRDEQKLDEQQQAL---WHARQEGHQRARHLRHTIQALRRQFSGALP 1269
Cdd:TIGR02168  654 lvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELEKALaelRKELEELEEELEQLRKELEELSRQISALRK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1270 -----LAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKvsewhKKLEDV 1344
Cdd:TIGR02168  734 dlarlEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-----EALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1345 RLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLEErqliwdqrevqLERQLDSYEKQQNEVLNTAQK 1424
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES-----------LAAEIEELEELIEELESELEA 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1425 FEEATGSLPDPNQPLANQLDYALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNvlsrdkvINELRLRLpaaAE 1504
Cdd:TIGR02168  878 LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR-------IDNLQERL---SE 947

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 688616510  1505 REKLLADLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVlkkyqNLLgkARQEQEEIAKRHEE 1568
Cdd:TIGR02168  948 EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPV-----NLA--AIEEYEELKERYDF 1004
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1771-2005 6.29e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 64.01  E-value: 6.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1771 KQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGL 1850
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1851 QAQVESDGPTVDALQK--KIRKLEHELDRKSISEPADKRSTLKedksskeEVVRWEegkkwQARVDKMRNVLKEKEREVD 1928
Cdd:COG4942   100 EAQKEELAELLRALYRlgRQPPLALLLSPEDFLDAVRRLQYLK-------YLAPAR-----REQAEELRADLAELAALRA 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616510 1929 SQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEAdKEIEELHKRNAELEQQIKVMKQQQALPRDAA 2005
Cdd:COG4942   168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELA-AELAELQQEAEELEALIARLEAEAAAAAERT 243
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 112-467 1.07e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.32  E-value: 1.07e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   112 DEIRQLESHLERKEKEVTQLEKEMGKERKSNEE-LALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESL 190
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQQLERLRREREKAERyQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   191 --QTKEESNEIQRRLTKANQQLYQCMEELQHA-EDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMD 267
Cdd:TIGR02169  260 isELEKRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   268 QLRKDRDHAKLQVreltDQIQARVEEDDPVMAAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKlrtaqMDSDKSNIIA 347
Cdd:TIGR02169  340 ELEREIEEERKRR----DKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE-----INELKRELDR 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   348 LQQVIYELCGAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQR 427
Cdd:TIGR02169  411 LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 688616510   428 AAQLAERDARDKDKELNDTLSRIRLYESGTDGLEAAISEI 467
Cdd:TIGR02169  491 ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQL 530
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 35-653 1.39e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 1.39e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   35 RDLKADDSEKMIQLFRISQTLLRMKLDEIKCAYEVVDSAGAEQARIENELKAKVLKLESELEMAQRvmgggDKHFLRDEI 114
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-----DIARLEERR 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  115 RQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEfyrkeAEQRESLQTKE 194
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA-----EAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  195 ESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRD 274
Cdd:COG1196   387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  275 HAKLQVRELTDQIQARVEEddpvmaavnakVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQMDSDKSNIIALQQVIYE 354
Cdd:COG1196   467 ELLEEAALLEAALAELLEE-----------LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  355 LCGAVQERdnqikMLSEQVEQYTTEMERNAMLIEELKRplkkdkghsSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAER 434
Cdd:COG1196   536 YEAALEAA-----LAAALQNIVVEDDEVAAAAIEYLKA---------AKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  435 DARDKD-KELNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRERLGLNP 513
Cdd:COG1196   602 DLVASDlREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL 681

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  514 KEELDLSEFRRSKILKQRQYKAENQVLLKEIERLEEERLELKQRIRALVKDKGVTVVSNSLLDNSVEEKPVRSLRPSSGS 593
Cdd:COG1196   682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616510  594 TdDEIKRKNERLQKELSNKEK-------ELElrrsestQFKAKLNEMLNENKQLEQGMKEILQAIQD 653
Cdd:COG1196   762 L-EELERELERLEREIEALGPvnllaieEYE-------ELEERYDFLSEQREDLEEARETLEEAIEE 820
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 814-1418 1.78e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 1.78e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  814 KEHQSERESWQKERDSFAELKSKLEEQREVDAVKIKEYNHLLETLEKDPSEIRREMAETGRKIVVLRVNEKCLTRRYTTL 893
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  894 LELEQHLRKENAKLKEdftqmqaavterigylqrfkemaafkmaslqksldvsvpasELERANKQyteltikyrnLLQKD 973
Cdd:COG1196   301 EQDIARLEERRRELEE-----------------------------------------RLEELEEE----------LAELE 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  974 NHLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTtggEIIMDKATKAVANSEIVSVSRRITTLE 1053
Cdd:COG1196   330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE---ELEELAEELLEALRAAAELAAQLEELE 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1054 MKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSVSKHISDADRKRITELEK 1133
Cdd:COG1196   407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1134 TEANLRIEVSKLREVSDVAKMQV--SALDARQQSREKEVESLRRQVLDYQAESDEKALIAKLHQHIVALQLSETTAISRL 1211
Cdd:COG1196   487 AEAAARLLLLLEAEADYEGFLEGvkAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1212 EATN----TRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRRQFSGALPLAQQEKFSNTMLHLQEDR 1287
Cdd:COG1196   567 KAAKagraTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL 646

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1288 ARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEikylkn 1367
Cdd:COG1196   647 REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE------ 720

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 688616510 1368 cvAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEV 1418
Cdd:COG1196   721 --LEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1439-1994 2.37e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.42  E-value: 2.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1439 LANQLDYALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLpaaAEREKLLADLSKQEDS 1518
Cdd:COG1196   230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIAR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1519 ESQpTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVRALHQKLDvymdtSLDRFKQTALELIKK 1598
Cdd:COG1196   307 LEE-RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE-----ALLEAEAELAEAEEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1599 ptitvpTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQMKgLSQEAEE 1678
Cdd:COG1196   381 ------LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE-AAEEEAE 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1679 LRAQLIQMEKELHYLRTELE--AQKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNA 1756
Cdd:COG1196   454 LEEEEEALLELLAELLEEAAllEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1757 AQKEEALnvqqivdkQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHL 1836
Cdd:COG1196   534 AAYEAAL--------EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1837 NELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSIS------EPADKRSTLKEDKSSKEEVVRWEEGKKWQ 1910
Cdd:COG1196   606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTlegeggSAGGSLTGGSRRELLAALLEAEAELEELA 685

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1911 ARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQ----------VVGARTLEADKEIEEL 1980
Cdd:COG1196   686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEelleeeelleEEALEELPEPPDLEEL 765

                         570
                  ....*....|....
gi 688616510 1981 HKRNAELEQQIKVM 1994
Cdd:COG1196   766 ERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 980-1686 3.83e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.77  E-value: 3.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   980 TTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAfenISTTGGEIIMDKATKAVANSEIVSVSRRITTLEMKELNE 1059
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELTAELQELEEK---LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1060 RQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSVSKhiSDADRKRITELEKTEANLR 1139
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE--LEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1140 IEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALiAKLHQHIVALQLSETTAISRLEATNTRLQ 1219
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL-KELQAELEELEEELEELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1220 KLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRH---------TIQALRRQFSGALPLAQQ-----EKFSNTMLHLQE 1285
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDSLERLQENlegfsegvkALLKNQSGLSGILGVLSElisvdEGYEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1286 DRAR--VREDAQITEEE----RRKAEGKAQELELKLKG-------LEELIATLKDAKGAQK-----VSEWHKKLED---- 1343
Cdd:TIGR02168  545 GRLQavVVENLNAAKKAiaflKQNELGRVTFLPLDSIKgteiqgnDREILKNIEGFLGVAKdlvkfDPKLRKALSYllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1344 VRLLE-----MRQSRELN-------------------------------TQREEIKYLKNCVAEQERTISGLEEELVQQN 1387
Cdd:TIGR02168  625 VLVVDdldnaLELAKKLRpgyrivtldgdlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1388 NLLEERQliwdQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLPDPNQPLANQLDYALGKIKEHVRTILETKTTCKIL 1467
Cdd:TIGR02168  705 KELEELE----EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1468 EEKLKEKEAALWSSEQNVLSRDKVINELRLRLpaAAEREKLLADLSKQEDSESQptLKVAHQTINNLQGRLDQKEEVLKK 1547
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAEL--TLLNEEAANLRERLESLERR--IAATERRLEDLEEQIEELSEDIES 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1548 YQNLLGKARQEQEEIAKRHEEEVrALHQKLDVYMDTSLDRFKQTALELikkptitvptSKHLVRLAEMEQTVAEQDNSLS 1627
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALL-NERASLEEALALLRSELEELSEEL----------RELESKRSELRRELEELREKLA 925

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 688616510  1628 SLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQMKGLSQEAEELRAQLIQM 1686
Cdd:TIGR02168  926 QLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 75-329 6.09e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 6.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    75 AEQARIENELKAKVLKLESELEMAQRVMGGGDK--HFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEA 152
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKelEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   153 EEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQ-RESL--------QTKEESNEIQRRLTKANQQLYQCMEELQHAEDM 223
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlREALdelraeltLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   224 AANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEddpvMAAVNA 303
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRE----LEELRE 922

                          250       260
                   ....*....|....*....|....*.
gi 688616510   304 KVEEWKSVLSGKDLEILEYQQMIRDL 329
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERLSEE 948
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1781-2650 6.68e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 6.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1781 RDLNEELQLAKdgVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVEsdgpT 1860
Cdd:TIGR02168  216 KELKAELRELE--LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK----E 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1861 VDALQKKIRKLEHELDRKSisepaDKRSTLKEDKSSKEEVvrweegkkwqarvdkmrnvLKEKEREVDSQAKQLATMKEL 1940
Cdd:TIGR02168  290 LYALANEISRLEQQKQILR-----ERLANLERQLEELEAQ-------------------LEELESKLDELAEELAELEEK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1941 YSRLEQEKVSLQKKLKgrgvtadqvvgartlEADKEIEELHKRNAELEQQIKVMKQQQALPRdAAMEDITNRNRYLEERL 2020
Cdd:TIGR02168  346 LEELKEELESLEAELE---------------ELEAELEELESRLEELEEQLETLRSKVAQLE-LQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2021 YSMESRLSKeppsrpsdrhstspsqlswsskvrsmtfdvieaeqtqssllnstvvvTEKEISVIEDKATQTSFRSIDMGT 2100
Cdd:TIGR02168  410 ERLEDRRER-----------------------------------------------LQQEIEELLKKLEEAELKELQAEL 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2101 AEVNQDDENVAKNKIDLEQKAlmkddktEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELT 2180
Cdd:TIGR02168  443 EELEEELEELQEELERLEEAL-------EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2181 HREMMEKPLDEDQLEVENE-ETNAEEMLYSTMNQaeletpkVLLEGDEDYGQEPEELLKCECDPSAESKELDEEETALSN 2259
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGyEAAIEAALGGRLQA-------VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQG 588

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2260 STTFDAKLVSEQPAMEKNKSFTP---EAGFNPNLSEVSTSREL-NANTENDILGHLKAKVTRLNDKEHSMKSKARKTSGR 2335
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDpklRKALSYLLGGVLVVDDLdNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKT 668

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2336 GSDTPSQR----------------EHEFQKENLRLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKR 2399
Cdd:TIGR02168  669 NSSILERRreieeleekieeleekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2400 LNHLRGsgrsgktipELEKTIGLMKKVVEKVQRENENLKRTSE--VNVQEQLATLERDHEKLKSEYEKLKGKQEE----- 2472
Cdd:TIGR02168  749 IAQLSK---------ELTELEAEIEELEERLEEAEEELAEAEAeiEELEAQIEQLKEELKALREALDELRAELTLlneea 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2473 -QLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEEthqrlLLAQSKGATLLGVDSKT 2551
Cdd:TIGR02168  820 aNLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-----LLNERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2552 WKSSVvtrlfENKMKGLESDIAKKNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNVpveatTDEGLAREYQSVR 2631
Cdd:TIGR02168  895 ELEEL-----SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL-----TLEEAEALENKIE 964

                          890
                   ....*....|....*....
gi 688616510  2632 LANKQLEREKAQLLRQIQR 2650
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1298-1922 7.04e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 7.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1298 EEERRKAEgKAQELELKLKGLEeliatlkdakgaqkVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTIS 1377
Cdd:COG1196   206 ERQAEKAE-RYRELKEELKELE--------------AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1378 GLEEELVQQNNLLEERQliwdQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLpdpnqplANQLDYALGKIKEHVRTI 1457
Cdd:COG1196   271 ELRLELEELELELEEAQ----AEEYELLAELARLEQDIARLEERRRELEERLEEL-------EEELAELEEELEELEEEL 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1458 LETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLpaAAEREKLLADLSKQEDSESQptLKVAHQTINNLQGR 1537
Cdd:COG1196   340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL--EELAEELLEALRAAAELAAQ--LEELEEAEEALLER 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1538 LDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVRALHQKLDvymdtsldrfkqtalelikkptitvptskhlvRLAEMEQ 1617
Cdd:COG1196   416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE--------------------------------EEEALLE 463

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1618 TVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQMKGLSQEAEELRAQLIQMEKEL-HYLRTE 1696
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYeAALEAA 543

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1697 LEAQKEANVRSPSNTMKNLVERLKNQLA--------LKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQI 1768
Cdd:COG1196   544 LAAALQNIVVEDDEVAAAAIEYLKAAKAgratflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1769 VDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLE-TLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLS 1847
Cdd:COG1196   624 GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGgSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 688616510 1848 SGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPADKRSTLKEDKSSKEEVVRWEEGKKWQARVDKMRNVLKE 1922
Cdd:COG1196   704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 694-1410 1.49e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 1.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   694 QVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSKSTGSsIPHKTLALPEEMTPTSAEaINALNEY 773
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE-LQKELYALANEISRLEQQ-KQILRER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   774 TVQLLQEIKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREVdavkikeynh 853
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ---------- 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   854 lLETLEKDPSEIRREMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQAAVTERIgylqrfkemaa 933
Cdd:TIGR02168  381 -LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE----------- 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   934 fkMASLQKSLDVSVpaSELERANKQYTELTIKYRNLLQKDNHLVQKTTSLEHLETENMSLRERIdsinKELEISKEKLH- 1012
Cdd:TIGR02168  449 --LEELQEELERLE--EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV----KALLKNQSGLSg 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1013 ---------TLEQAFEN-ISTTGGE----IIMDKATKAVANSE------------IVSVSRRITTLEMKELNERQRAEHA 1066
Cdd:TIGR02168  521 ilgvlseliSVDEGYEAaIEAALGGrlqaVVVENLNAAKKAIAflkqnelgrvtfLPLDSIKGTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1067 QKMYEHLRNSLKQV-----------------------------EERNFELE----------TKFAELTKLNLEAQRIE-R 1106
Cdd:TIGR02168  601 LGVAKDLVKFDPKLrkalsyllggvlvvddldnalelakklrpGYRIVTLDgdlvrpggviTGGSAKTNSSILERRREiE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1107 ELRDELADSVSKhiSDADRKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDE 1186
Cdd:TIGR02168  681 ELEEKIEELEEK--IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1187 KA---------------LIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRAR 1251
Cdd:TIGR02168  759 LEaeieeleerleeaeeELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1252 HLRHTIQALRRQfsgalpLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEgkaQELELKLKGLEELIATLKDAkgA 1331
Cdd:TIGR02168  839 RLEDLEEQIEEL------SEDIESLAAEIEELEELIEELESELEALLNERASLE---EALALLRSELEELSEELREL--E 907

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616510  1332 QKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTisgLEEELVQQNNLLEERQLIWDQREVQLERQLDS 1410
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL---TLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1455-2260 2.43e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 2.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1455 RTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLP---AAAEREKLLADLSKQEDSESqptLKVAHQTI 1531
Cdd:TIGR02168  158 RAIFEEAAGISKYKERRKETERKLERTRENLDRLEDILNELERQLKsleRQAEKAERYKELKAELRELE---LALLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1532 NNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEE---EVRALHQKLDVYmdtsldrfkQTALELIKKptitvptskh 1608
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEEL---------QKELYALAN---------- 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1609 lvRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQvtaaQAMEHAADMARLEDKHA---AQMKGLSQEAEELRAQLIQ 1685
Cdd:TIGR02168  296 --EISRLEQQKQILRERLANLERQLEELEAQLEELES----KLDELAEELAELEEKLEelkEELESLEAELEELEAELEE 369

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1686 MEKELHYLRTELEAQKEAnvrspSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQiitNAAQKEEALNV 1765
Cdd:TIGR02168  370 LESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL---EEAELKELQAE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1766 QQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKE---ALEEHLNELKKK 1842
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEgvkALLKNQSGLSGI 521

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1843 IQRLSSGLQAQVE------------SDGPTVDALQKKIRKLE----HELDRKSISE-----PADKRSTLKEDKSSKEEVV 1901
Cdd:TIGR02168  522 LGVLSELISVDEGyeaaieaalggrLQAVVVENLNAAKKAIAflkqNELGRVTFLPldsikGTEIQGNDREILKNIEGFL 601

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1902 RW-EEGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELysRLEQEKVSLQ-KKLKGRGVTADQVVGAR--TLEADKEI 1977
Cdd:TIGR02168  602 GVaKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKL--RPGYRIVTLDgDLVRPGGVITGGSAKTNssILERRREI 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1978 EELHKRNAELEQQIKVMKQQQALPRDAAmEDITNRNRYLEERLYSMESRLS--KEPPSRPSDRHSTSPSQLSWSSKVRSM 2055
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKEL-EELEEELEQLRKELEELSRQISalRKDLARLEAEVEQLEERIAQLSKELTE 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2056 TFDVIEAEQTQSSLLNSTVVVTEKEISVIEDKATQTS----------------FRSIDMGTAEVNQDDENVAKNKIDLEQ 2119
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKeelkalrealdelraeLTLLNEEAANLRERLESLERRIAATER 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2120 KALMKDDKTEQEESNKEK--GSVEKDEEQPDETQRGQDVAVFEYAQEEL---KTNDEAEELESELthREMMEKPLD-EDQ 2193
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESlaAEIEELEELIEELESELEALLNERASLEEalaLLRSELEELSEEL--RELESKRSElRRE 916

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616510  2194 LEVENEETNAEEMLYSTMNQAELETPKVLLegdEDYGQEPEELLKCECDPSAESKELDEEETALSNS 2260
Cdd:TIGR02168  917 LEELREKLAQLELRLEGLEVRIDNLQERLS---EEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 226-1101 2.45e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 2.45e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   226 NLRSENEHLQKnLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKdrdhakLQVRELTDQIQARVEEDDPVMAAVNAKV 305
Cdd:TIGR02168  180 KLERTRENLDR-LEDILNELERQLKSLERQAEKAERYKELKAELRE------LELALLVLRLEELREELEELQEELKEAE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   306 EEWKSvlsgKDLEILEYQQMIRDLREKLRTAQMDSDksniiALQQVIYELCGAVQERDNQIKMLSEQVEQYTTEMERNAM 385
Cdd:TIGR02168  253 EELEE----LTAELQELEEKLEELRLEVSELEEEIE-----ELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   386 LIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDKDKElndtlsrirlyesgtdgLEAAIS 465
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ-----------------LETLRS 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   466 EIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRERLGLNPKEELDLSEFRRSKILKQRQykAENQVLLKEIE 545
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQ--EELERLEEALE 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   546 RLEEERLELKQRIRALvkdkgvtvvsnslldnsveekpvRSLRPSSGSTDDEIKRKNERLQKeLSNKEKELELRRSESTQ 625
Cdd:TIGR02168  465 ELREELEEAEQALDAA-----------------------ERELAQLQARLDSLERLQENLEG-FSEGVKALLKNQSGLSG 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   626 FKAKLNEMLNENKQLEQGMKEILQA-IQDTQKKTPTSTGVSIPSLER----LVNALEMKYSEGKFDASLHL--RTQVDQL 698
Cdd:TIGR02168  521 ILGVLSELISVDEGYEAAIEAALGGrLQAVVVENLNAAKKAIAFLKQnelgRVTFLPLDSIKGTEIQGNDReiLKNIEGF 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   699 TGRNEELRQEMKTAREEAANTLSQ------LTKANEKIARLESEMESMSKsTGSSIPHKTLalpeeMTPTSAEAINALNE 772
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYLLGGvlvvddLDNALELAKKLRPGYRIVTL-DGDLVRPGGV-----ITGGSAKTNSSILE 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   773 YTvqllQEIKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQREvdavKIKEYN 852
Cdd:TIGR02168  675 RR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA----EVEQLE 746

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   853 HLLETLEKDPSEIRREMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQAAVT---ERIGYLQRFK 929
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTllnEEAANLRERL 826

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   930 EMAAFKMASLQKSLDVSvpASELERANKQYTELTikyRNLLQKDNHLVQKTTSLEHLETENMSLRERIDSINKELEISKE 1009
Cdd:TIGR02168  827 ESLERRIAATERRLEDL--EEQIEELSEDIESLA---AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1010 KLHTLEQAFENIsttggeiimdKATKAVANSEIVSVSRRITTLEMKELNERQR--------AEHAQKMYEHLRNSLKQVE 1081
Cdd:TIGR02168  902 ELRELESKRSEL----------RRELEELREKLAQLELRLEGLEVRIDNLQERlseeysltLEEAEALENKIEDDEEEAR 971

                          890       900
                   ....*....|....*....|
gi 688616510  1082 ERNFELETKFAELTKLNLEA 1101
Cdd:TIGR02168  972 RRLKRLENKIKELGPVNLAA 991
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1668-2503 3.57e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 3.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1668 QMKGLSQEAEE-LRAQLIQMEKElHYLRTELEAQKEANVRSPSNTMKNLvERLKNQLALKEKQLKALSKALLELRAELtS 1746
Cdd:TIGR02169  199 QLERLRREREKaERYQALLKEKR-EYEGYELLKEKEALERQKEAIERQL-ASLEEELEKLTEEISELEKRLEEIEQLL-E 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1747 QAEQQIitNAAQKEEALNVQQIVDKQTKELRACVR---DLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQN 1823
Cdd:TIGR02169  276 ELNKKI--KDLGEEEQLRVKEKIGELEAEIASLERsiaEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1824 KLQSEKEALEEHLNELKKKIQRLSSGLQAQVESdgptVDALQKKIRKLEHELDrkSISEPADKRSTLKEDKSS-----KE 1898
Cdd:TIGR02169  354 KLTEEYAELKEELEDLRAELEEVDKEFAETRDE----LKDYREKLEKLKREIN--ELKRELDRLQEELQRLSEeladlNA 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1899 EVVRWEEG-KKWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKG-----------RGVTADQVV 1966
Cdd:TIGR02169  428 AIAGIEAKiNELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKlqrelaeaeaqARASEERVR 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1967 GAR--TLEADKEIEELHKRNAELeqqIKVMKQQQALPRDAA--------MEDITNRNRYLEERLYSMESRLSKEPPSRPS 2036
Cdd:TIGR02169  508 GGRavEEVLKASIQGVHGTVAQL---GSVGERYATAIEVAAgnrlnnvvVEDDAVAKEAIELLKRRKAGRATFLPLNKMR 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2037 DRHStsPSQLSWSSKVRSMTFDVIEAEQTQSS----LLNSTVVVTEKEisviEDKATQTSFRSIDMGTAEVNQDDENVAK 2112
Cdd:TIGR02169  585 DERR--DLSILSEDGVIGFAVDLVEFDPKYEPafkyVFGDTLVVEDIE----AARRLMGKYRMVTLEGELFEKSGAMTGG 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2113 NKIDLEQKALMKDDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELTHREMMEKPLDED 2192
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER 738

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2193 QLEVENEETNAEEMLysTMNQAELET-PKVLLEGDEDYGQEPEELLKCECDPS--------AESKELDEEETALSNST-T 2262
Cdd:TIGR02169  739 LEELEEDLSSLEQEI--ENVKSELKElEARIEELEEDLHKLEEALNDLEARLShsripeiqAELSKLEEEVSRIEARLrE 816

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2263 FDAKLVSEQPAMEKNKSftpeagfnpnlsEVSTSRELNANTENDIlGHLKAKVTRLNDKEHSMKSKARKTSGRGSDTPSQ 2342
Cdd:TIGR02169  817 IEQKLNRLTLEKEYLEK------------EIQELQEQRIDLKEQI-KSIEKEIENLNGKKEELEEELEELEAALRDLESR 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2343 REHefqkenlrLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKRLNHLRGSGRSGKTIPELEKTIGL 2422
Cdd:TIGR02169  884 LGD--------LKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLED 955

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2423 MKKVVEKVQRENENLKRTSEVNVQEQLATLERdheklkseYEKLKGKQEeqlnsRLESKTKGIEKIMMENERLRKEIKKE 2502
Cdd:TIGR02169  956 VQAELQRVEEEIRALEPVNMLAIQEYEEVLKR--------LDELKEKRA-----KLEEERKAILERIEEYEKKKREVFME 1022


                   .
gi 688616510  2503 A 2503
Cdd:TIGR02169 1023 A 1023
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 111-416 7.20e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.53  E-value: 7.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   111 RDEIRQLESHLERKEKEVTQLEKEMgkerksnEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESL 190
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKAL-------AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   191 --QTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQ 268
Cdd:TIGR02168  749 iaQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   269 LRKDRDHAKLQVRELTDQI---QARVEEDDPVMAAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQ-----MDS 340
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIeelSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSeelreLES 908

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616510   341 DKSNIIALQQVIYELCGAVQERDNQIKM-LSEQVEQYTTEMERNAMLIEELKRPLKKDkghSSDHQRRLEDLSAKLQ 416
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVrIDNLQERLSEEYSLTLEEAEALENKIEDD---EEEARRRLKRLENKIK 982
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1663-1891 1.30e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.70  E-value: 1.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1663 DKHAAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKEAnvrspSNTMKNLVERLKNQLALKEKQLKALSKALLELRA 1742
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR-----IAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1743 ELTSQAEQ-----------------QIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLakdgVRAAKARENSLK 1805
Cdd:COG4942    98 ELEAQKEElaellralyrlgrqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE----LAALRAELEAER 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1806 EDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESdgptvdaLQKKIRKLEHELDRKSISEPAD 1885
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE-------LEALIARLEAEAAAAAERTPAA 246


                  ....*.
gi 688616510 1886 KRSTLK 1891
Cdd:COG4942   247 GFAALK 252
PTZ00121 PTZ00121
MAEBL; Provisional
 975-1835 2.71e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  975 HLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKA------TKAVANSEIVSVSRR 1048
Cdd:PTZ00121  993 HILQKPTCVIDKENHFSFTALTANTIDFNQNFNIEKIEELTEYGNNDDVLKEKDIIDEDidgnheGKAEAKAHVGQDEGL 1072

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1049 ITTLEMKELN--ERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSVSKHISDADRK 1126
Cdd:PTZ00121 1073 KPSYKDFDFDakEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAK 1152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1127 RITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALIAKLHQHivALQLSETT 1206
Cdd:PTZ00121 1153 RVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAED--AKKAEAVK 1230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1207 AISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQ---ALRRQFSGALPLAQQEKFSNTMLHL 1283
Cdd:PTZ00121 1231 KAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADElkkAEEKKKADEAKKAEEKKKADEAKKK 1310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1284 QEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLE-MRQSRELNTQREEI 1362
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEaKKKADAAKKKAEEK 1390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1363 KYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLPDPNQPLANQ 1442
Cdd:PTZ00121 1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1443 LDYALGKIKEHVRTILETKTTC----KILEEKLKEKEAALWSSEQNVLSRDKVINELRlrlpaAAEREKLLADLSKQEDS 1518
Cdd:PTZ00121 1471 KADEAKKKAEEAKKADEAKKKAeeakKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-----KAEEAKKADEAKKAEEK 1545

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1519 ESQPTLKVAHQtinnlqgrLDQKEEVLKKYQnllGKARQEQEEIAKRHEEEVRALHQKLDVYMDTSLDRFKQTALELIKK 1598
Cdd:PTZ00121 1546 KKADELKKAEE--------LKKAEEKKKAEE---AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK 1614

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1599 PTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLED-KHAAQMKGLSQEAE 1677
Cdd:PTZ00121 1615 AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEaKKAEEDEKKAAEAL 1694

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1678 ELRAQLIQMEKELHYLRTElEAQKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAA 1757
Cdd:PTZ00121 1695 KKEAEEAKKAEELKKKEAE-EKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1758 QKEEALNVQQIVDKQTKELRACV----RDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQnklQSEKEALE 1833
Cdd:PTZ00121 1774 RKEKEAVIEEELDEEDEKRRMEVdkkiKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQ---LEEADAFE 1850


                  ..
gi 688616510 1834 EH 1835
Cdd:PTZ00121 1851 KH 1852
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 75-648 3.85e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 56.23  E-value: 3.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    75 AEQARIENELKAKvlKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEE 154
Cdd:TIGR02169  301 AEIASLERSIAEK--ERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDK 378

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   155 KNR-------KLKREIKQLTRKNEQLQQDIEFYRKEAEQRES----------------LQTKEESNEIQRRLTKANQQLY 211
Cdd:TIGR02169  379 EFAetrdelkDYREKLEKLKREINELKRELDRLQEELQRLSEeladlnaaiagieakiNELEEEKEDKALEIKKQEWKLE 458

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   212 QCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVREL-------- 283
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLgsvgerya 538

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   284 -------TDQIQARVEEDDPVMAAVNAKVEEWK-------------------SVLS-----GKDLEILEYQQMIRD---- 328
Cdd:TIGR02169  539 taievaaGNRLNNVVVEDDAVAKEAIELLKRRKagratflplnkmrderrdlSILSedgviGFAVDLVEFDPKYEPafky 618

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   329 ------LREKLRTAQMDSDKSNIIALQQVIYELCGAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSS 402
Cdd:TIGR02169  619 vfgdtlVVEDIEAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELR 698

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   403 DHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDKDKELNDTLSRIRLYEsgtDGLEAAISEIKECKNQIRVRDREIE 482
Cdd:TIGR02169  699 RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE---QEIENVKSELKELEARIEELEEDLH 775

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   483 GMIKEINQLEMKIN-----NLLDENEDLRERLGLNPKEELDLSEFRRSKILKQRQYKAENQVLLKEIERLEEERLELKQR 557
Cdd:TIGR02169  776 KLEEALNDLEARLShsripEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE 855

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   558 IRALVKDKGVTvvsnslldNSVEEKPVRSLRPSSGSTDDeIKRKNERLQKELSNKEK-------ELELRRSESTQFKAKL 630
Cdd:TIGR02169  856 IENLNGKKEEL--------EEELEELEAALRDLESRLGD-LKKERDELEAQLRELERkieeleaQIEKKRKRLSELKAKL 926

                          650
                   ....*....|....*...
gi 688616510   631 NEMLNENKQLEQGMKEIL 648
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDE 944
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 54-740 4.84e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.83  E-value: 4.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    54 TLLRMKLDEIKCAYEVVDSAGAEQARIENELKAKVLKLESELEMAQRvmgggDKHFLRDEIRQLESHLERKEKEVTQLEK 133
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS-----KVAQLELQIASLNNEIERLEARLERLED 414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   134 EMGKERKSNEELALRAEEAEeknrkLKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQtkEESNEIQRRLTKANQQLYQC 213
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEAE-----LKELQAELEELEEELEELQEELERLEEALEELR--EELEEAEQALDAAERELAQL 487

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   214 MEELQHAEDMAANLRSENEHLQKNLEES---------VKEMEKMTDEYNK----------MKIAVQQTDAIMD--QLRKD 272
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQsglsgilgvLSELISVDEGYEAaieaalggrlQAVVVENLNAAKKaiAFLKQ 567

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   273 RDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGKDLE-------ILEYQQMIRDLREKLRTAQMDSDKSNI 345
Cdd:TIGR02168  568 NELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyLLGGVLVVDDLDNALELAKKLRPGYRI 647

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   346 IALQQVIYELCGAV-----------QERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAK 414
Cdd:TIGR02168  648 VTLDGDLVRPGGVItggsaktnssiLERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   415 LQVAERKVLEAQRAAQLAERDARDKDKELNDTLSRIRLYESGTDGLEAAISEIKEcknqirvrdreiegmikEINQLEMK 494
Cdd:TIGR02168  728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA-----------------EIEELEAQ 790

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   495 INNLLDENEDLRERLGLNPKEELDLSEFRRSKILKQRQYKAEnqvllkeierleeeRLELKQRIRALVKDKGvtvvsnsl 574
Cdd:TIGR02168  791 IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR--------------IAATERRLEDLEEQIE-------- 848

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   575 lDNSVEEKPVRSLRPSSGSTDDEIKRKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEilqaiqdt 654
Cdd:TIGR02168  849 -ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE-------- 919

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   655 qkktptstgvsipsLERLVNALEMKYSEgkfdaslhLRTQVDQLTGR-NEELRQEMKTAREEAANTLSQLTKANEKIARL 733
Cdd:TIGR02168  920 --------------LREKLAQLELRLEG--------LEVRIDNLQERlSEEYSLTLEEAEALENKIEDDEEEARRRLKRL 977


                   ....*..
gi 688616510   734 ESEMESM 740
Cdd:TIGR02168  978 ENKIKEL 984
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1725-1954 6.46e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.31  E-value: 6.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1725 LKEKQLKALSKALLELRAELtSQAEQQIITnAAQKEEALnvQQIVDKQTKELRAcvRDLNEELQLAKDGVRAAKARE--N 1802
Cdd:COG4913   218 LEEPDTFEAADALVEHFDDL-ERAHEALED-AREQIELL--EPIRELAERYAAA--RERLAELEYLRAALRLWFAQRrlE 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1803 SLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQrlssglqaqvESDGPTVDALQKKIRKLEHELDRKsise 1882
Cdd:COG4913   292 LLEAELEELRAELARLEAELERLEARLDALREELDELEAQIR----------GNGGDRLEQLEREIERLERELEER---- 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1883 pADKRSTLKE--------DKSSKEEVvrWEEGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKK 1954
Cdd:COG4913   358 -ERRRARLEAllaalglpLPASAEEF--AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 76-337 7.30e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 7.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    76 EQARIENELKAKVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQ-------LEKEMGKERKSNEELALR 148
Cdd:TIGR02169  201 ERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKlteeiseLEKRLEEIEQLLEELNKK 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   149 AEE-AEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAE--QRESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAA 225
Cdd:TIGR02169  281 IKDlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEdaEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYA 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   226 NLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDhaklQVRELTDQIQARVEEDDPVMAAVNAKV 305
Cdd:TIGR02169  361 ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELD----RLQEELQRLSEELADLNAAIAGIEAKI 436

                          250       260       270
                   ....*....|....*....|....*....|..
gi 688616510   306 EEWKSVLSGKDLEILEYQQMIRDLREKLRTAQ 337
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1611-1953 9.97e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.69  E-value: 9.97e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1611 RLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDkhaaqmkgLSQEAEELRAQLIQMEKEL 1690
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ--------LEQEEEKLKERLEELEEDL 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1691 HYLRTELEAQKEAnvrspsntmknlVERLKNQLALKEKQLKALSKALLELRAELtSQAEQQIITNAAQKEEALNVQQI-- 1768
Cdd:TIGR02169  747 SSLEQEIENVKSE------------LKELEARIEELEEDLHKLEEALNDLEARL-SHSRIPEIQAELSKLEEEVSRIEar 813

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1769 ---VDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQR 1845
Cdd:TIGR02169  814 lreIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1846 LSSGLQaqvesdgptvdALQKKIRKLEHELDRKS--ISEPADKRSTLKEDKSSKEEVVRW---------------EEGKK 1908
Cdd:TIGR02169  894 LEAQLR-----------ELERKIEELEAQIEKKRkrLSELKAKLEALEEELSEIEDPKGEdeeipeeelsledvqAELQR 962

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 688616510  1909 WQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQK 1953
Cdd:TIGR02169  963 VEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 77-334 1.72e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    77 QARIEnELKAKVLKLESELEMAQRVMgggdkHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKN 156
Cdd:TIGR02169  680 RERLE-GLKRELSSLQSELRRIENRL-----DELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEI 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   157 RKLKREIKQLTRKNEQLQQDIEFYRKEAE--------------QRESLQTKEESNEIQRRLTKANQQLYQCMEELQHAED 222
Cdd:TIGR02169  754 ENVKSELKELEARIEELEEDLHKLEEALNdlearlshsripeiQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   223 MAANLRSENEHLQ-------KNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELT---DQIQARVE 292
Cdd:TIGR02169  834 EIQELQEQRIDLKeqiksieKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELErkiEELEAQIE 913

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 688616510   293 EDDPVMAAVNAKVEEWKSVLS------GKDLEILEYQQMIRDLREKLR 334
Cdd:TIGR02169  914 KKRKRLSELKAKLEALEEELSeiedpkGEDEEIPEEELSLEDVQAELQ 961
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2364-2692 2.44e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.52  E-value: 2.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2364 QLEQANKDLPRLKDQVSDLKEMCSVLKKEkAEVEKRLNHLRGSGRsgktipELEKTIGLMKKVVEKVQRENenlkrtsev 2443
Cdd:TIGR02168  180 KLERTRENLDRLEDILNELERQLKSLERQ-AEKAERYKELKAELR------ELELALLVLRLEELREELEE--------- 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2444 nVQEQLATLERDHEKLKSEYEKLKGKQEEqLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKL 2523
Cdd:TIGR02168  244 -LQEELKEAEEELEELTAELQELEEKLEE-LRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2524 KAELEETHQRLLLAQSKGATLlgvdsktwksSVVTRLFENKMKGLESDIAKKNISISELKVQLKEANEKLQATQHTVIQL 2603
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAEL----------EEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2604 KEQVELLKNvpveatTDEGLAREYQSVRLANKQLEREKAQLLRQIQRN---EVQLGTNKDGPGYTELQEQIKAANNEKKK 2680
Cdd:TIGR02168  392 ELQIASLNN------EIERLEARLERLEDRRERLQQEIEELLKKLEEAelkELQAELEELEEELEELQEELERLEEALEE 465

                          330
                   ....*....|..
gi 688616510  2681 LQDEVRKLTQEL 2692
Cdd:TIGR02168  466 LREELEEAEQAL 477
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1351-1884 2.61e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.20  E-value: 2.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1351 QSRELNTQREEIK-YLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEAT 1429
Cdd:pfam15921  293 QANSIQSQLEIIQeQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQES 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1430 GSLPDPNQPLANQL--------------------DYALGKIKEHVRTILETKTT-CKILEEKLKEKEAALWSSEQNVLSR 1488
Cdd:pfam15921  373 GNLDDQLQKLLADLhkrekelslekeqnkrlwdrDTGNSITIDHLRRELDDRNMeVQRLEALLKAMKSECQGQMERQMAA 452

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1489 DKVINELRLR---LPAAAEREKLLADLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKAR-------QE 1558
Cdd:pfam15921  453 IQGKNESLEKvssLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRsrvdlklQE 532

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1559 QEEIaKRHEEEVRALHQKLDVYMDTSLDRFKQTALELIKKPTITVPTSKH-------LVRLAEMEQTVAEQDNSLsslsQ 1631
Cdd:pfam15921  533 LQHL-KNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHgrtagamQVEKAQLEKEINDRRLEL----Q 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1632 KLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQM---KGLSQEAEELRAQLIQMEKELHYLRTELEAQKEaNVRSP 1708
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR-NFRNK 686

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1709 SNTMKNLVERLKNQLALKEKQLKalskallelraeltsQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQ 1788
Cdd:pfam15921  687 SEEMETTTNKLKMQLKSAQSELE---------------QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQ 751

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1789 LAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKI 1868
Cdd:pfam15921  752 FLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQE 831

                          570       580
                   ....*....|....*....|.
gi 688616510  1869 R-----KLEHELDRKSISEPA 1884
Cdd:pfam15921  832 QesvrlKLQHTLDVKELQGPG 852
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 988-1986 2.74e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.13  E-value: 2.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   988 TENMSLRERIDSINKELEISKeKLHTLEQAFENISTTGGEIIMDKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQ 1067
Cdd:TIGR00606  166 SEGKALKQKFDEIFSATRYIK-ALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1068 KMYEHLRNSLKQVEE---RNFELETKFAELTKLNLEAQRIERELRDEL------ADSVSKHISDADRKRITELEKTEANL 1138
Cdd:TIGR00606  245 NELDPLKNRLKEIEHnlsKIMKLDNEIKALKSRKKQMEKDNSELELKMekvfqgTDEQLNDLYHNHQRTVREKERELVDC 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1139 RIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALIAKLHQHivalqlsETTAISRLEATNTRL 1218
Cdd:TIGR00606  325 QRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGF-------ERGPFSERQIKNFHT 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1219 QKLEaqklrdeqkldeqqqalwhaRQEGHQRarhlrhTIQALRRQFSGALPLAQQEkfsntmlhLQEDRARVREDAQITE 1298
Cdd:TIGR00606  398 LVIE--------------------RQEDEAK------TAAQLCADLQSKERLKQEQ--------ADEIRDEKKGLGRTIE 443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1299 EERRKAEGKAQELELKLKGLEELIATLKDAkgAQKVSEWHKKLEDVRLLEMRQSRElnTQREEIKYLKNCVAEQERTISG 1378
Cdd:TIGR00606  444 LKKEILEKKQEELKFVIKELQQLEGSSDRI--LELDQELRKAERELSKAEKNSLTE--TLKKEVKSLQNEKADLDRKLRK 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1379 LEEELVQQNNLLEERQliwdQREVQLERQLDSYEKQQNevlNTAQKFEEATGSLPD-PNQPLANQLDYALGKIKehvrti 1457
Cdd:TIGR00606  520 LDQEMEQLNHHTTTRT----QMEMLTKDKMDKDEQIRK---IKSRHSDELTSLLGYfPNKKQLEDWLHSKSKEI------ 586

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1458 letkttcKILEEKLKEKEAALWSSEQNvlsRDKVINELRLRLPAAAEREKLLADLSKQEDSESQ-PTLKVAHQTINNLQG 1536
Cdd:TIGR00606  587 -------NQTRDRLAKLNKELASLEQN---KNHINNELESKEEQLSSYEDKLFDVCGSQDEESDlERLKEEIEKSSKQRA 656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1537 RLDQKEEVLKKYQNLLGKARQEQEEIAKR---HEEEVRALHQKLDVYMDTSLDRFKQTALELIKKPTitvpTSKHLVRLA 1613
Cdd:TIGR00606  657 MLAGATAVYSQFITQLTDENQSCCPVCQRvfqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK----RRDEMLGLA 732

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1614 EMEQTVAE-QDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQ-----MKGLSQEAEELRAQLIQME 1687
Cdd:TIGR00606  733 PGRQSIIDlKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLtdvtiMERFQMELKDVERKIAQQA 812

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1688 KELHYLRTELEA----QKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAEltsqaEQQIITNAAQKeeal 1763
Cdd:TIGR00606  813 AKLQGSDLDRTVqqvnQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSE-----KLQIGTNLQRR---- 883

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1764 nvqQIVDKQTKELRACVRDLNEELQLAKDGVRA-AKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEE---HLNEL 1839
Cdd:TIGR00606  884 ---QQFEEQLVELSTEVQSLIREIKDAKEQDSPlETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNihgYMKDI 960

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1840 KKKIQRLSSGLQAQVESDGPTVDALQKkirklEHELDRKSISEpaDKRSTLKEDKSSKEEvvrwEEGKKWQARVDKMRNV 1919
Cdd:TIGR00606  961 ENKIQDGKDDYLKQKETELNTVNAQLE-----ECEKHQEKINE--DMRLMRQDIDTQKIQ----ERWLQDNLTLRKRENE 1029

                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 688616510  1920 LKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGR----GVTADQVVGARTLEADKEIEELHKRNAE 1986
Cdd:TIGR00606 1030 LKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRnhvlALGRQKGYEKEIKHFKKELREPQFRDAE 1100
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 57-536 2.91e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.20  E-value: 2.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    57 RMKLDEIKCAYEVVDsagaEQARIENELKAKVLkleSELEMAQRVMgggdKHFLRDEIRQLESHLERKEKEVTQLEKEMG 136
Cdd:pfam15921  291 RSQANSIQSQLEIIQ----EQARNQNSMYMRQL---SDLESTVSQL----RSELREAKRMYEDKIEELEKQLVLANSELT 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   137 KERKSNEELalrAEEAEEKNRKLKREIKQLTRKNEQLQQdiefyrkEAEQRESLQTKEESNEIQrrLTKANQQLYQCMEE 216
Cdd:pfam15921  360 EARTERDQF---SQESGNLDDQLQKLLADLHKREKELSL-------EKEQNKRLWDRDTGNSIT--IDHLRRELDDRNME 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   217 LQHAEDMAANLRSEnehLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRK--DRDHAKLQVRELTDQ----IQAR 290
Cdd:pfam15921  428 VQRLEALLKAMKSE---CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKvvEELTAKKMTLESSERtvsdLTAS 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   291 VEEDDPVMAAVNAKVEEWKSVLsgkDLEILEYQQMiRDLREKLRTAQMDSDKsniIALQqviyelcgaVQERDNQIKMLS 370
Cdd:pfam15921  505 LQEKERAIEATNAEITKLRSRV---DLKLQELQHL-KNEGDHLRNVQTECEA---LKLQ---------MAEKDKVIEILR 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   371 EQVE---QYTTEMERNAMLIEELKRPLKKDKghssdHQRRLEdlsaklqVAERKVLEAQRAAQLAERDARDKDKElndtL 447
Cdd:pfam15921  569 QQIEnmtQLVGQHGRTAGAMQVEKAQLEKEI-----NDRRLE-------LQEFKILKDKKDAKIRELEARVSDLE----L 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   448 SRIRLYESGTDGLEaAISEIKECKNQirvrdreiegMIKEINQLEMKINNLLDENEDLRERLgLNPKEELDLSEFRRSKI 527
Cdd:pfam15921  633 EKVKLVNAGSERLR-AVKDIKQERDQ----------LLNEVKTSRNELNSLSEDYEVLKRNF-RNKSEEMETTTNKLKMQ 700


                   ....*....
gi 688616510   528 LKQRQYKAE 536
Cdd:pfam15921  701 LKSAQSELE 709
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
56-254 4.89e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 4.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   56 LRMKLDEIKCAYEVVDSAGAEQARIENELKAkvlkLESELEMAQRVmggGDKHFLRDEIRQLESHLERKEKEVTQLEKEM 135
Cdd:COG4913   612 LAALEAELAELEEELAEAEERLEALEAELDA----LQERREALQRL---AEYSWDEIDVASAEREIAELEAELERLDASS 684

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  136 GKERKSNEELA---LRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRRLTKANQQlyq 212
Cdd:COG4913   685 DDLAALEEQLEeleAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD--- 761

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 688616510  213 cmeelQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNK 254
Cdd:COG4913   762 -----AVERELRENLEERIDALRARLNRAEEELERAMRAFNR 798
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 788-1568 4.99e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 4.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   788 IEQLGSALEEYKRKFAVIRhqqgLLYKEHQSERESWQKERDSFAELKSKLEEQREVDAvkiKEYNHLLETLEKDPSEIRR 867
Cdd:TIGR02169  172 KEKALEELEEVEENIERLD----LIIDEKRQQLERLRREREKAERYQALLKEKREYEG---YELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   868 EMAETGRKIVVLrvnEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQAAVTERIGYLQ----------RFKEMAAFKMA 937
Cdd:TIGR02169  245 QLASLEEELEKL---TEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEaeiaslersiAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   938 SLQKSLDVSVP---------ASELERANKQYTELTIKYRNLLQKDNHLVQKTTSLE----HLETENMSLRERIDSINKEL 1004
Cdd:TIGR02169  322 ERLAKLEAEIDkllaeieelEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDkefaETRDELKDYREKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1005 EISKEKLHTLEQAFENISTTGGEIIMD----KATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQV 1080
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAiagiEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1081 EERNFELETKFAEL---TKLNLEAQRIERELRDELADSVS------KHISDADRKRITELEKTEANLRIEVskLREVSDV 1151
Cdd:TIGR02169  482 EKELSKLQRELAEAeaqARASEERVRGGRAVEEVLKASIQgvhgtvAQLGSVGERYATAIEVAAGNRLNNV--VVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1152 AKMQVSALDARQQSR------------EKEVESLRRQ-VLDYQ---AESDEKaliaklHQHIVALQLSETTAISRLEA-- 1213
Cdd:TIGR02169  560 AKEAIELLKRRKAGRatflplnkmrdeRRDLSILSEDgVIGFAvdlVEFDPK------YEPAFKYVFGDTLVVEDIEAar 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1214 ---------------------------------TNTRLQKLEAQKLRDE-QKLDEQQQALWHARQEGHQRARHLRHTIQA 1259
Cdd:TIGR02169  634 rlmgkyrmvtlegelfeksgamtggsraprggiLFSRSEPAELQRLRERlEGLKRELSSLQSELRRIENRLDELSQELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1260 LRRQFSGALplAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHK 1339
Cdd:TIGR02169  714 ASRKIGEIE--KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1340 KLEDVRllemRQSRELNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEvl 1419
Cdd:TIGR02169  792 RIPEIQ----AELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE-- 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1420 nTAQKFEEATGSLpdpnqplaNQLDYALGKIKehvRTILETKTTCKILEEKLKEKEAALWSSEQNvlsrdkvINELRLRL 1499
Cdd:TIGR02169  866 -LEEELEELEAAL--------RDLESRLGDLK---KERDELEAQLRELERKIEELEAQIEKKRKR-------LSELKAKL 926

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616510  1500 PAAAEREKLLADLSKQEDSESQPTLkvahqTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEE 1568
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPEEEL-----SLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDE 990
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1391-2037 5.18e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.28  E-value: 5.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1391 EERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLpdpNQPLANQLDYALGKIKEHVRTILETKTTCKILEEK 1470
Cdd:TIGR00618  164 EKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQL---LTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQ 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1471 LKEKEAALWSSEQNVLSRDKVINELRLRLPAAAEREKLLADLSKQEDSESQPTLKVAHQtinnlqgrlDQKEEVLKKYQN 1550
Cdd:TIGR00618  241 SHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHI---------KAVTQIEQQAQR 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1551 LLGKARQEQEEIAKRHEEEVRALHQKLDVYMDTSLDRFKQTALELIKKPTiTVPTS--KHLVRLAEMEQTVAEQDNSLSS 1628
Cdd:TIGR00618  312 IHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAH-EVATSirEISCQQHTLTQHIHTLQQQKTT 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1629 LSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDK-HAAQMKGLSQEAEELRAQLIQMEkelhylrTELEAQKEANVRS 1707
Cdd:TIGR00618  391 LTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLaHAKKQQELQQRYAELCAAAITCT-------AQCEKLEKIHLQE 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1708 PSNTMKNLVERLKN--QLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQIVdkqtkelRACVRDLNE 1785
Cdd:TIGR00618  464 SAQSLKEREQQLQTkeQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT-------RRMQRGEQT 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1786 ELQLAKDGvRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQ 1865
Cdd:TIGR00618  537 YAQLETSE-EDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQH 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1866 KKIRKLEHELDRKSIS--------EPADKRSTL--------KEDKSSKEEVVRWEEGKKWQARVDKM------------- 1916
Cdd:TIGR00618  616 ALLRKLQPEQDLQDVRlhlqqcsqELALKLTALhalqltltQERVREHALSIRVLPKELLASRQLALqkmqsekeqltyw 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1917 RNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAELEQQIKVMKQ 1996
Cdd:TIGR00618  696 KEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQ 775

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 688616510  1997 QQALPRDAAmEDITNRNRYLEERLYSMESRLSKEPPSRPSD 2037
Cdd:TIGR00618  776 TGAELSHLA-AEIQFFNRLREEDTHLLKTLEAEIGQEIPSD 815
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
61-509 5.94e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 5.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   61 DEIKCAYEVVDSAGAEQARIE--NELKAKVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMgke 138
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAEL--- 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  139 rksnEELALRAEEAEEKNRKLKREIKQL-TRKNEQLQQDIEfyrkeaeqreslQTKEESNEIQRRLTKANQQLYQCMEEL 217
Cdd:COG4913   312 ----ERLEARLDALREELDELEAQIRGNgGDRLEQLEREIE------------RLERELEERERRRARLEALLAALGLPL 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  218 QHAEDMAANLRSENEHLQKNLEESVKEME----KMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQI--QARV 291
Cdd:COG4913   376 PASAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALaeALGL 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  292 EEDDPVMAA----VNAKVEEWKS----VLSGKDLEIL----EYQQMIR-----DLREKLRTAQMDSDKSNIIAL------ 348
Cdd:COG4913   456 DEAELPFVGelieVRPEEERWRGaierVLGGFALTLLvppeHYAAALRwvnrlHLRGRLVYERVRTGLPDPERPrldpds 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  349 ---------------------QQVIYELCGAVQE---------RDNQIKMLSEQVEQYTTEMER--------NAMLIEEL 390
Cdd:COG4913   536 lagkldfkphpfrawleaelgRRFDYVCVDSPEElrrhpraitRAGQVKGNGTRHEKDDRRRIRsryvlgfdNRAKLAAL 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  391 KRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQL--AERDARDKDKELNDTLSRIRLYESGTDGLEAAISEIK 468
Cdd:COG4913   616 EAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYswDEIDVASAEREIAELEAELERLDASSDDLAALEEQLE 695

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|.
gi 688616510  469 ECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRERL 509
Cdd:COG4913   696 ELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRL 736
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1615-1833 6.55e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.94  E-value: 6.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1615 MEQTVAEQDNSLSSLSQKLKIVTQELDQ-QRQVTAAQAMEHAADMARLEDKHAAQMKGLSQEAEELRAQLIQMEKELHYL 1693
Cdd:COG3206   166 LELRREEARKALEFLEEQLPELRKELEEaEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1694 RTELEAQKEANVRSPSNTmknLVERLKNQLALKEKQLKALSK-------ALLELRAELtSQAEQQIitnaaqKEEALNVQ 1766
Cdd:COG3206   246 RAQLGSGPDALPELLQSP---VIQQLRAQLAELEAELAELSArytpnhpDVIALRAQI-AALRAQL------QQEAQRIL 315

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616510 1767 QIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENslkeDLETLNKDLQRSQKSQNKLQSEKEALE 1833
Cdd:COG3206   316 ASLEAELEALQAREASLQAQLAQLEARLAELPELEA----ELRRLEREVEVARELYESLLQRLEEAR 378
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 178-535 8.27e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 8.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   178 EFYRKEAEQRESLQTKEES-NEIQRRLTKANQQLYQCMEELQHAEdmaanlrsENEHLQKNLEESvkEMEKMTDEYNKMK 256
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENiERLDLIIDEKRQQLERLRREREKAE--------RYQALLKEKREY--EGYELLKEKEALE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   257 IAVQQTDAIMDQLRKDRDhaklQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVlsgkdlEILEYQQMIRDLreklrTA 336
Cdd:TIGR02169  237 RQKEAIERQLASLEEELE----KLTEEISELEKRLEEIEQLLEELNKKIKDLGEE------EQLRVKEKIGEL-----EA 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   337 QMDSDKSNIIALQQVIYELCGAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQ 416
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   417 VAERKVLEAQRAAQLAERDARDKDKELNDTLSRIRLYESGTDGLEAAISEIKECKNQIrvrDREIEGMIKEINQLEMKIN 496
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINEL---EEEKEDKALEIKKQEWKLE 458

                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 688616510   497 NLLDENEDLRERLgLNPKEELDLSEFRRSKilKQRQYKA 535
Cdd:TIGR02169  459 QLAADLSKYEQEL-YDLKEEYDRVEKELSK--LQRELAE 494
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 600-1222 8.41e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.66  E-value: 8.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   600 RKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGVSIPSLERLVNALEMK 679
Cdd:pfam15921  138 QSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRS 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   680 YSEGKFDASLHLRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANE-KIARLESEME---SMSKSTGSSIPHKTLAL 755
Cdd:pfam15921  218 LGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQdRIEQLISEHEveiTGLTEKASSARSQANSI 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   756 PEEMTPTSAEAINALNEYTVQLlqeiKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKS 835
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQL----SDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESG 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   836 KLEEQ----------REVDAVKIKEYNHLLETLEKDPS----EIRREMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLR 901
Cdd:pfam15921  374 NLDDQlqklladlhkREKELSLEKEQNKRLWDRDTGNSitidHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   902 KENAKLKEDFTQMQAAVTERIGYLQRFKEMAAFKMASLQKS----LDVSVPASELERA----NKQYTELTIKYRNLLQKD 973
Cdd:pfam15921  454 QGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSertvSDLTASLQEKERAieatNAEITKLRSRVDLKLQEL 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   974 NHLVQKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKatkavANSEIVSVSRRITTLE 1053
Cdd:pfam15921  534 QHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEK-----AQLEKEINDRRLELQE 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1054 MKELNERQRAEhaqkmyehlrnsLKQVEERNFELETKFAELTKLNLEAQRIEREL---RDELADSVSKHISDADrKRITE 1130
Cdd:pfam15921  609 FKILKDKKDAK------------IRELEARVSDLELEKVKLVNAGSERLRAVKDIkqeRDQLLNEVKTSRNELN-SLSED 675

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1131 LEKTEANLRIEVSKLREVSDVAKMQVsaldarqQSREKEVESLRRQVLDYQAESDEKALIAklhqhiVALQLSETTAISR 1210
Cdd:pfam15921  676 YEVLKRNFRNKSEEMETTTNKLKMQL-------KSAQSELEQTRNTLKSMEGSDGHAMKVA------MGMQKQITAKRGQ 742

                          650
                   ....*....|..
gi 688616510  1211 LEATNTRLQKLE 1222
Cdd:pfam15921  743 IDALQSKIQFLE 754
PRK11281 PRK11281
mechanosensitive channel MscK;
1674-1838 9.93e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.45  E-value: 9.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1674 QEAEELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKNL-VERLKNQLALKEKQLKALSKALLELRAELTS---QAE 1749
Cdd:PRK11281   80 EETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLsLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSlqtQPE 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1750 --QQIITNAAQKEEALNVQQIVDKQTKE-LRACVRD-LNEELQL--AKDGVRAAKARENSLKEDLETLNKDLQRSQksQN 1823
Cdd:PRK11281  160 raQAALYANSQRLQQIRNLLKGGKVGGKaLRPSQRVlLQAEQALlnAQNDLQRKSLEGNTQLQDLLQKQRDYLTAR--IQ 237

                         170
                  ....*....|....*
gi 688616510 1824 KLQSEKEALEEHLNE 1838
Cdd:PRK11281  238 RLEHQLQLLQEAINS 252
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
126-742 1.47e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 1.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  126 KEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESlqTKEESNEIQRRLTK 205
Cdd:PRK03918  172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE--LKEEIEELEKELES 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  206 ANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEEsVKEMEKMTDEYNKMKiavqqtdAIMDQLRKDRDHAKLQVRELTD 285
Cdd:PRK03918  250 LEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE-LKELKEKAEEYIKLS-------EFYEEYLDELREIEKRLSRLEE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  286 QIQArVEEDDPVMAAVNAKVEEWKSVLSG--KDLEILE-YQQMIRDLREKLRTAQMDSDKSNIIALQQVIYELcgavqer 362
Cdd:PRK03918  322 EING-IEERIKELEEKEERLEELKKKLKEleKRLEELEeRHELYEEAKAKKEELERLKKRLTGLTPEKLEKEL------- 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  363 dnqikmlsEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDKDke 442
Cdd:PRK03918  394 --------EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKR-- 463

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  443 lndtlsrirlyesgtdgLEAAISEIKECKNQIRVRDREIEGMIKEINQLeMKINNLLDENEDLRERLGLNPKEELDlSEF 522
Cdd:PRK03918  464 -----------------IEKELKEIEEKERKLRKELRELEKVLKKESEL-IKLKELAEQLKELEEKLKKYNLEELE-KKA 524

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  523 RRSKILKQRQYKAENQVllKEIERLEEERLELKQRIRALVKDKGvtvvsnslldnSVEEKPVRSLRPSSGSTDDEIKRKN 602
Cdd:PRK03918  525 EEYEKLKEKLIKLKGEI--KSLKKELEKLEELKKKLAELEKKLD-----------ELEEELAELLKELEELGFESVEELE 591

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  603 ERLQKELSNKEKELELRRSEStqfkaKLNEMLNENKQLEQGMKEILQAIQDTQKKtptstgvsIPSLERLVNALEMKYSE 682
Cdd:PRK03918  592 ERLKELEPFYNEYLELKDAEK-----ELEREEKELKKLEEELDKAFEELAETEKR--------LEELRKELEELEKKYSE 658

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  683 GKFDASLHLRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSK 742
Cdd:PRK03918  659 EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEK 718
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
57-195 1.60e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 50.63  E-value: 1.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   57 RMKLDEIKcaYEVVDSAGAEQArIEnELKAKVLKLESELEMAQRVMGGGDKHFLRDEIRQLESHLERKEKEVTQLEKEMG 136
Cdd:COG2433   362 DVDRDEVK--ARVIRGLSIEEA-LE-ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELE 437

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 688616510  137 KERKSNEELALRAEEA-EEKNRKLK--REIKQLTRKNEQLQQDIEfyrKEAEQRESLQTKEE 195
Cdd:COG2433   438 EKDERIERLERELSEArSEERREIRkdREISRLDREIERLERELE---EERERIEELKRKLE 496
PTZ00121 PTZ00121
MAEBL; Provisional
 1765-2533 1.95e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 1.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1765 VQQIVDKQTKELRACVRDLNEElqlAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHlnelKKKIQ 1844
Cdd:PTZ00121 1029 IEELTEYGNNDDVLKEKDIIDE---DIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEA----FGKAE 1101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1845 RLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSisepadkrstlkEDKSSKEEVVRWEEGKkwqaRVDKMRNVLKEKE 1924
Cdd:PTZ00121 1102 EAKKTETGKAEEARKAEEAKKKAEDARKAEEARKA------------EDARKAEEARKAEDAK----RVEIARKAEDARK 1165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1925 REVDSQAKQLATMKELYSRLEQEKVSLQKKLKgrgvTADQVVGARTLEADKEIEELhkRNAELEQQIKVMKQQQALPRDA 2004
Cdd:PTZ00121 1166 AEEARKAEDAKKAEAARKAEEVRKAEELRKAE----DARKAEAARKAEEERKAEEA--RKAEDAKKAEAVKKAEEAKKDA 1239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2005 AMEDITNRNRYLEERLYSMESRLSKEPPSRPSDR--HSTSPSQLSWSSKVRSMTfDVIEAEQTQSSLLNSTVVVTEKEIS 2082
Cdd:PTZ00121 1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKaeEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKAD 1318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2083 VIEDKATQTSFRSidmgtAEVNQDDENVAKNKIDLEQKALMKDDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYA 2162
Cdd:PTZ00121 1319 EAKKKAEEAKKKA-----DAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2163 QEELKTNDEAEELESELTHREMMEKPLDEDQLEVEnEETNAEEMlystMNQAELETPKVLLEGDEDYGQEPEELLKcecd 2242
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE-EKKKADEA----KKKAEEAKKADEAKKKAEEAKKAEEAKK---- 1464

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2243 PSAESKELDEEETALSNSTTFDAKLVSEQPAMEKNKSFTPEAGFNPNLSEVSTSRELNANTENDilghlKAKVTRLNDKE 2322
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-----KAEEAKKADEA 1539

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2323 HSMKSKARKTSGRGSDTPSQREHEFQKENLRLSTENLELRFQLEQANKDLPrlKDQVSDLKEMCSVLKKEKAEVEKRLNH 2402
Cdd:PTZ00121 1540 KKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE--EARIEEVMKLYEEEKKMKAEEAKKAEE 1617

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2403 LRGSGRsgktipELEKTIGLMKKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKG---KQEEQLNSRLE 2479
Cdd:PTZ00121 1618 AKIKAE------ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAeeaKKAEEDEKKAA 1691

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....
gi 688616510 2480 SKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEETHQR 2533
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 110-288 2.20e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  110 LRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQR-- 187
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELlr 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  188 -----------ESLQTKEESNEIQRRLT---KANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKmtdEYN 253
Cdd:COG4942   112 alyrlgrqpplALLLSPEDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE---ERA 188

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 688616510  254 KMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQ 288
Cdd:COG4942   189 ALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1125-1315 2.58e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 2.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1125 RKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQsrekevesLRRQVLDYQAESDEkalIAKLHQHIVALQlse 1204
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE--------ALQRLAEYSWDEID---VASAEREIAELE--- 674

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1205 tTAISRLEATNTRLQKLEAQ--KLRDE-QKLDEQQQALWHARQEGHQRARHLRHTIQALRRQFSGALPLAQQEKFSN--T 1279
Cdd:COG4913   675 -AELERLDASSDDLAALEEQleELEAElEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleE 753

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 688616510 1280 MLHLQEDRARVREDAQITEEERRKAEGKAQELELKL 1315
Cdd:COG4913   754 RFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 77-236 3.69e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 49.26  E-value: 3.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    77 QARIEnELKAKVLKLESELEMaqrvmgggdkhfLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELalraEEAEEKN 156
Cdd:pfam05667  341 QEQLE-DLESSIQELEKEIKK------------LESSIKQVEEELEELKEQNEELEKQYKVKKKTLDLL----PDAEENI 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   157 RKLKREIKQLTRKNEQLQQDIEFYR----KEAEQRESLQTKEESnEIQRRLTKA---NQQLYQCMEELQHAEDMAANLRS 229
Cdd:pfam05667  404 AKLQALVDASAQRLVELAGQWEKHRvpliEEYRALKEAKSNKED-ESQRKLEEIkelREKIKEVAEEAKQKEELYKQLVA 482


                   ....*..
gi 688616510   230 ENEHLQK 236
Cdd:pfam05667  483 EYERLPK 489
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1757-2030 3.80e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.30  E-value: 3.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1757 AQKEEALNVQQIVDKQTKELRACVRDLNEELQ-LAKDGVRAAKARE-----------------NSLKEDLETLNKDLQRS 1818
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLErLRREREKAERYQAllkekreyegyellkekEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1819 QKSQNKLQSEK-------EALEEHLNELKKKIQRLSSGLQAQVESDGPTVDA----LQKKIRKLEHEL---DRKSISEPA 1884
Cdd:TIGR02169  250 EEELEKLTEEIselekrlEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAeiasLERSIAEKERELedaEERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1885 DKRSTLKEDKSSKEEVVRWE-EGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTAD 1963
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERkRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELD 409

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616510  1964 QVVgartleadKEIEELHKRNAELEQQIKVMKQQQAlPRDAAMEDITNRNRYLEERLYSMESRLSKE 2030
Cdd:TIGR02169  410 RLQ--------EELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWKLEQLAADLSKY 467
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
117-510 4.47e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.27  E-value: 4.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  117 LESHLERKEkEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAE----QRESLQT 192
Cdd:PRK02224  243 LEEHEERRE-ELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEaveaRREELED 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  193 KEEsnEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKD 272
Cdd:PRK02224  322 RDE--ELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRER 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  273 RDHAKLQVRELTDQIQARVEEDDpvmaAVNAKVEEWKSVLSGKDLEILEYQQMI---------RDLREKLRTAQMDSDKS 343
Cdd:PRK02224  400 FGDAPVDLGNAEDFLEELREERD----ELREREAELEATLRTARERVEEAEALLeagkcpecgQPVEGSPHVETIEEDRE 475

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  344 NIIALQQVIYELCGAVQERDNQIKMLSEQVEQyttemernAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVL 423
Cdd:PRK02224  476 RVEELEAELEDLEEEVEEVEERLERAEDLVEA--------EDRIERLEERREDLEELIAERRETIEEKRERAEELRERAA 547

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  424 EAQRAAQLAERDARDKDKELNDTLSRIRLYESGTDGLEAAIseikECKNQIRVRDREIEGMIKEINQLEMKINNLLDENE 503
Cdd:PRK02224  548 ELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERI----ESLERIRTLLAAIADAEDEIERLREKREALAELND 623


                  ....*..
gi 688616510  504 DLRERLG 510
Cdd:PRK02224  624 ERRERLA 630
PTZ00121 PTZ00121
MAEBL; Provisional
 59-292 4.95e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.37  E-value: 4.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   59 KLDEIKCAYEVVDSAGAEQARIENELKAKVLKLESELEMaqrvmgggdkhflRDEIRQLESHLERKEKEVTQLEKEMGKE 138
Cdd:PTZ00121 1593 RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE-------------KKKVEQLKKKEAEEKKKAEELKKAEEEN 1659

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  139 RKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRRLTKANQQLYQCMEELQ 218
Cdd:PTZ00121 1660 KIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA 1739

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 688616510  219 HAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVqqtdaIMDQLRKDRDHAKLQVRELTDQIQARVE 292
Cdd:PTZ00121 1740 EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV-----IEEELDEEDEKRRMEVDKKIKDIFDNFA 1808
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
110-508 6.38e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 6.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  110 LRDEIRQLESHLERKEKEVtqleKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRES 189
Cdd:PRK03918  212 ISSELPELREELEKLEKEV----KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  190 LQ---------------TKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRsENEHLQKNLEESVKEMEKMTDEYNK 254
Cdd:PRK03918  288 LKekaeeyiklsefyeeYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLE-ELKKKLKELEKRLEELEERHELYEE 366

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  255 MKIAVQQTDAIMDQLR-----------KDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSV-----LSGKDLE 318
Cdd:PRK03918  367 AKAKKEELERLKKRLTgltpeklekelEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpVCGRELT 446

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  319 -------ILEYQQMIRDLREKLRTA--QMDSDKSNIIALQQVIYELCGAVQERD--NQIKMLSEQVEQYTTE-MERNAML 386
Cdd:PRK03918  447 eehrkelLEEYTAELKRIEKELKEIeeKERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKKYNLEeLEKKAEE 526

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  387 IEELKRPLKKDKGHSS---DHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDKD----KELNDTLSRIRLYESGTDG 459
Cdd:PRK03918  527 YEKLKEKLIKLKGEIKslkKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfesvEELEERLKELEPFYNEYLE 606

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 688616510  460 LEAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRER 508
Cdd:PRK03918  607 LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKK 655
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 110-349 7.29e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 7.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  110 LRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRes 189
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ-- 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  190 lqtKEESNEIQRRLTKANQQLYqcMEELQHAEDMAANLRSenehlQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQL 269
Cdd:COG4942   103 ---KEELAELLRALYRLGRQPP--LALLLSPEDFLDAVRR-----LQYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  270 RKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQMDSDKSNIIALQ 349
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALK 252
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 1713-1873 8.68e-05

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 48.13  E-value: 8.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1713 KNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAqkEEALNVQQIVDKQTKELRACVRDLNEELQLAKD 1792
Cdd:pfam13166  320 ELDVEDIESEAEVLNSQLDGLRRALEAKRKDPFKSIELDSVDAKI--ESINDLVASINELIAKHNEITDNFEEEKNKAKK 397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1793 GVRAAkaRENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIqrlsSGLQAQVESDGPTVDALQKKIRKLE 1872
Cdd:pfam13166  398 KLRLH--LVEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKLREEI----KELEAQLRDHKPGADEINKLLKAFG 471


                   .
gi 688616510  1873 H 1873
Cdd:pfam13166  472 F 472
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1969-2727 9.71e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 9.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1969 RTLEADKEIEELHKRNAELEQQIKVMKQQQALPRDAAMEDITNRNRYLEERLYSMESRLSKEPPSRPSDRHSTSPSQLSW 2048
Cdd:pfam02463  185 LAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2049 SSKVRSMTFDVIEAEQTQSSLLNSTVVVTEKEISVIE----DKATQTSFRSIDMGTAEVNQDDENVAKNKIDLEQKALMK 2124
Cdd:pfam02463  265 EKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllklERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2125 DDKTEQEESNKEKGSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAEELESELTHREMMEKpLDEDQLEVENEETNAE 2204
Cdd:pfam02463  345 KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEA-QLLLELARQLEDLLKE 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2205 EMLYSTMNQAELETPKVLLEGDEDYGQEPEELL---KCECDPSAESKELDEEETALSNSTTFDAKLVSEQPAMEKNKSFT 2281
Cdd:pfam02463  424 EKKEELEILEEEEESIELKQGKLTEEKEELEKQelkLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2282 P-EAGFNPNLSEVSTSRELNANTENDILGHLKAKVTRLNDKEHSMKSKARKTSGRGSDTPSQREHEFQKENLRLSTENLE 2360
Cdd:pfam02463  504 KaRSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLL 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2361 LRFQLEQANKDLP---------RLKDQVSDLKEMCSVLKKEKAEVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQ 2431
Cdd:pfam02463  584 IPKLKLPLKSIAVleidpilnlAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSE 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2432 RENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKGKQEEQLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRV 2511
Cdd:pfam02463  664 VKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQ 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2512 AKASLEVANEKLKAELEETHQRLLLAQSKGATLLGVDSKTWKSSVVTRLFENKMKGLESDIAKKNISISELKVQLKEANE 2591
Cdd:pfam02463  744 KIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLL 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2592 KLQATQHTVIQLKEQVELLKNVPVEATTDEGLAREYQSVRLANKQLEREKAQLLRQIQRNEVQLGTNKDGPGYTELQE-- 2669
Cdd:pfam02463  824 IEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEle 903

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 688616510  2670 ---QIKAANNEKKKLQDEVRKLTQELKHFDPTFFEELEDLKFNYNLEVKKNIVLEEQLKKL 2727
Cdd:pfam02463  904 eesQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 954-1842 1.29e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.76  E-value: 1.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   954 RANKQYTELTIKYRNLLQKDNHLVQKTTSLEHLETENMSLRERIDSINKELEiskEKLHTLEQAFENIS-TTGGEIIMDK 1032
Cdd:TIGR02169  217 LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLE---EIEQLLEELNKKIKdLGEEEQLRVK 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1033 ATKAVANSEIVSVSRRIttlEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQrierELRDEL 1112
Cdd:TIGR02169  294 EKIGELEAEIASLERSI---AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYA----ELKEEL 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1113 ADSVSkhisdadrkRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAE-SDEKALIA 1191
Cdd:TIGR02169  367 EDLRA---------ELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAiAGIEAKIN 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1192 KLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQrarhLRHTIQALRRQFSGALPLA 1271
Cdd:TIGR02169  438 ELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE----AEAQARASEERVRGGRAVE 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1272 QQEKFSNTMLH-LQEDRARVREDAQITEEERRKAEGKAQELELKLKGlEELIATLKDAKGAqkvsewhkKLEDVRLLEMR 1350
Cdd:TIGR02169  514 EVLKASIQGVHgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVA-KEAIELLKRRKAG--------RATFLPLNKMR 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1351 QS-RELNTQREE--IKYLKNCV---AEQERTISGLEEELVQQNNLLEERQLIWDQREVQLERQLdsyekqqnevlntaqk 1424
Cdd:TIGR02169  585 DErRDLSILSEDgvIGFAVDLVefdPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEGEL---------------- 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1425 FEEATGSLPDPNQPLANQLDYALGKIKEhvrtiletkttcKILEEKLKEKEAALWSSEQNVLSRDKVINELRLRLPAAae 1504
Cdd:TIGR02169  649 FEKSGAMTGGSRAPRGGILFSRSEPAEL------------QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDA-- 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1505 reklladlsKQEDSESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVRALHQKldvymdts 1584
Cdd:TIGR02169  715 ---------SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL-------- 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1585 ldrfkQTALELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELD------QQRQVTAAQAMEHAADM 1658
Cdd:TIGR02169  778 -----EEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEylekeiQELQEQRIDLKEQIKSI 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1659 ARLEDKHAAQMKGLSQEAEELRAQLIQMEKELHYLRTELEaqkeaNVRSPSNTMKNLVERLKNQLALKEKQLKALSKALL 1738
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERD-----ELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1739 ELRAELTsqaeqQIITNAAQKEEALNVQQIVDKQTKELRACVRDLneelqlakdgvRAAKARENSLKEDLETLNKDLQRS 1818
Cdd:TIGR02169  928 ALEEELS-----EIEDPKGEDEEIPEEELSLEDVQAELQRVEEEI-----------RALEPVNMLAIQEYEEVLKRLDEL 991

                          890       900
                   ....*....|....*....|....
gi 688616510  1819 QKSQNKLQSEKEALEEHLNELKKK 1842
Cdd:TIGR02169  992 KEKRAKLEEERKAILERIEEYEKK 1015
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1626-2027 1.38e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 1.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1626 LSSLSQKLKIVTQELD--QQRQVTAAQAMEHAADMARLEDKHAAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKEA 1703
Cdd:PRK02224  208 LNGLESELAELDEEIEryEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRER 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1704 --NVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELtSQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVR 1781
Cdd:PRK02224  288 leELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRL-EECRVAAQAHNEEAESLREDADDLEERAEELREEAA 366

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1782 DLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQaqvesdgptv 1861
Cdd:PRK02224  367 ELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR---------- 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1862 dALQKKIRKLEHELDrksisepADKRSTLKEDKSSKEEVVRWEEGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELY 1941
Cdd:PRK02224  437 -TARERVEEAEALLE-------AGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1942 SRLEqekvslqkKLKGRGVTADQVVGAR--TLEADKE-IEELHKRNAELEQQIKVMKQQQALPRDAAmEDITNRNRYLEE 2018
Cdd:PRK02224  509 DRIE--------RLEERREDLEELIAERreTIEEKRErAEELRERAAELEAEAEEKREAAAEAEEEA-EEAREEVAELNS 579


                  ....*....
gi 688616510 2019 RLYSMESRL 2027
Cdd:PRK02224  580 KLAELKERI 588
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1498-1743 1.44e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1498 RLPAAAER-EKLLADLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEiakrHEEEVRALHQK 1576
Cdd:COG4913   256 PIRELAERyAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDA----LREELDELEAQ 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1577 LDvymDTSLDRfkqtaLELIKKptitvptskhlvRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAA 1656
Cdd:COG4913   332 IR---GNGGDR-----LEQLER------------EIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1657 DMARLEDKHAAqmkgLSQEAEELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKnLVERLKNQLALKEKQLKALSKa 1736
Cdd:COG4913   392 LLEALEEELEA----LEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLA-LRDALAEALGLDEAELPFVGE- 465


                  ....*..
gi 688616510 1737 LLELRAE 1743
Cdd:COG4913   466 LIEVRPE 472
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1321-1565 1.52e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1321 LIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEELV---QQNNLLEERQLIW 1397
Cdd:COG4942     9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRaleQELAALEAELAEL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1398 DQREVQLERQLDSYEKQQNEVLNTAQKFEEATG-----SLPDPNQPLANQ--LDYALGKIKEHVRTILETKTTCKILEEK 1470
Cdd:COG4942    89 EKEIAELRAELEAQKEELAELLRALYRLGRQPPlalllSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAE 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1471 LKEKEAALWSSEQNVLSRDKVINELRlrlpaaAEREKLLADLSKQEDSESQptlkvahqtinnlqgRLDQKEEVLKKYQN 1550
Cdd:COG4942   169 LEAERAELEALLAELEEERAALEALK------AERQKLLARLEKELAELAA---------------ELAELQQEAEELEA 227

                         250
                  ....*....|....*
gi 688616510 1551 LLGKARQEQEEIAKR 1565
Cdd:COG4942   228 LIARLEAEAAAAAER 242
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1666-1889 1.56e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.75  E-value: 1.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1666 AAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKEAnvrspsntmknlVERLKNQLALKEKQLKALSKALLELRAELT 1745
Cdd:COG3883    22 QKELSELQAELEAAQAELDALQAELEELNEEYNELQAE------------LEALQAEIDKLQAEIAEAEAEIEERREELG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1746 SQAEQQ-----------IITNAAQKEEALN----VQQIVDKQTKELRAcVRDLNEELQLAKDGVRAAKARENSLKEDLET 1810
Cdd:COG3883    90 ERARALyrsggsvsyldVLLGSESFSDFLDrlsaLSKIADADADLLEE-LKADKAELEAKKAELEAKLAELEALKAELEA 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616510 1811 LNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPADKRST 1889
Cdd:COG3883   169 AKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAA 247
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
978-1401 1.67e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 1.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  978 QKTTSLEHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIImdkATKAVANSEIVSVSRRITTLEMKE- 1056
Cdd:PRK02224  248 ERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLL---AEAGLDDADAEAVEARREELEDRDe 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1057 ------LNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAEL------TKLNLEAQRIERELRDELADSVSKHISDAD 1124
Cdd:PRK02224  325 elrdrlEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELeseleeAREAVEDRREEIEELEEEIEELRERFGDAP 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1125 --------------------RKRITELEKTEANLRIEVSKLREVSDVAKM-----------QVSALDARQQSREK---EV 1170
Cdd:PRK02224  405 vdlgnaedfleelreerdelREREAELEATLRTARERVEEAEALLEAGKCpecgqpvegspHVETIEEDRERVEEleaEL 484

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1171 ESLRRQVLDYQAESDEKALIAKLHQHIVALQLSETTAISRLEATNTRL--QKLEAQKLRDE-QKLDEQQQALWHARQEGH 1247
Cdd:PRK02224  485 EDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIeeKRERAEELRERaAELEAEAEEKREAAAEAE 564

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1248 QRARHLRHTIQALRRQFSgalPLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKD 1327
Cdd:PRK02224  565 EEAEEAREEVAELNSKLA---ELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEA 641

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 688616510 1328 AKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNcvaeqerTISGLEEELVQQNNLLEERQLIWDQRE 1401
Cdd:PRK02224  642 EFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQA-------EIGAVENELEELEELRERREALENRVE 708
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1606-1837 2.09e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 2.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1606 SKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHA---AQMKGLSQEAEELRAQ 1682
Cdd:COG4913   231 VEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLElleAELEELRAELARLEAE 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1683 LIQMEKELHYLRTELEAQKEANVRSPSNTmknlVERLKNQLALKEKQLKALSKALLELrAELTSQAEQQIITNAAQKEEA 1762
Cdd:COG4913   311 LERLEARLDALREELDELEAQIRGNGGDR----LEQLEREIERLERELEERERRRARL-EALLAALGLPLPASAEEFAAL 385

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616510 1763 LnvqqivdkqtKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQN----KLQSEKEALEEHLN 1837
Cdd:COG4913   386 R----------AEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSnipaRLLALRDALAEALG 454
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
110-510 2.52e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 2.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  110 LRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRES 189
Cdd:COG4717    51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPL 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  190 LQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEE--------SVKEMEKMTDEYNKMKIAVQQ 261
Cdd:COG4717   131 YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEElleqlslaTEEELQDLAEELEELQQRLAE 210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  262 TDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGKDLEILEYQQMIRD---LREKLRTAQM 338
Cdd:COG4717   211 LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlfLVLGLLALLF 290

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  339 DSDKSNIIALQQVIYELCGAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKdkghssdHQRRLEDLSAKLQVA 418
Cdd:COG4717   291 LLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEE-------LQELLREAEELEEEL 363

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  419 ERKVLEAQRAAQLAERDARDKDkELNDTLSRIRLYESGTDGLEAAISEIKECKNQIR--VRDREIEGMIKEINQLEMKIN 496
Cdd:COG4717   364 QLEELEQEIAALLAEAGVEDEE-ELRAALEQAEEYQELKEELEELEEQLEELLGELEelLEALDEEELEEELEELEEELE 442

                         410
                  ....*....|....
gi 688616510  497 NLLDENEDLRERLG 510
Cdd:COG4717   443 ELEEELEELREELA 456
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1026-1846 2.60e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.89  E-value: 2.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1026 GEIIMDKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRIE 1105
Cdd:pfam02463  163 AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1106 REL---RDELADSVSKHISDADRKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQA 1182
Cdd:pfam02463  243 QELlrdEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1183 ESDEKALIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQRARhlRHTIQALRR 1262
Cdd:pfam02463  323 KKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK--LKEEELELK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1263 QFSGALPLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQE----------LELKLKGLEELIATLKDAKGAQ 1332
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEekeelekqelKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1333 KVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLE-ERQLIWDQREVQLERQLDSY 1411
Cdd:pfam02463  481 KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEnYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1412 EKQQNEVLNTAQKFEEATGSLPDPNQPLANQLDYALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVLSRDKV 1491
Cdd:pfam02463  561 EERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKES 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1492 INELRLRLPAAAEREKLLADLSKQEDSESQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVR 1571
Cdd:pfam02463  641 AKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1572 ALHQKLDVYMDTSLDRFKQTALELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQA 1651
Cdd:pfam02463  721 ELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1652 MEHAADMARLEDKHAAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKNLVERLKNQLALKEKQLK 1731
Cdd:pfam02463  801 EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1732 ALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETL 1811
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE 960

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 688616510  1812 NKDLQRSQKSQ-----NKLQSEKEALEEHLNELKKKIQRL 1846
Cdd:pfam02463  961 RNKRLLLAKEElgkvnLMAIEEFEEKEERYNKDELEKERL 1000
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1503-1725 3.02e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1503 AEREKLLADLSKQEDSeSQPTLKVAHQTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVRALHQKLDVYMD 1582
Cdd:COG4942    37 AELEKELAALKKEEKA-LLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1583 TSldrfKQTALELIKKPTITVPTSKHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLE 1662
Cdd:COG4942   116 LG----RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALE 191

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 688616510 1663 ---DKHAAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKNLVERLKNQLAL 1725
Cdd:COG4942   192 alkAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKLPW 257
PTZ00121 PTZ00121
MAEBL; Provisional
 59-346 3.36e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 3.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   59 KLDEIKCAYEVVDSAGAEQAriENELKAKVLKLESELEMAQRVMGGGDKHFLRDE----IRQLESHLERKEKEVTQLEKE 134
Cdd:PTZ00121 1523 KADEAKKAEEAKKADEAKKA--EEKKKADELKKAEELKKAEEKKKAEEAKKAEEDknmaLRKAEEAKKAEEARIEEVMKL 1600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  135 MGKERKSNEELALRAEEAEEKNRKLKREiKQLTRKNEQLQQDIEFYRKEAEQresLQTKEESNEIQR-RLTKANQQLYQC 213
Cdd:PTZ00121 1601 YEEEKKMKAEEAKKAEEAKIKAEELKKA-EEEKKKVEQLKKKEAEEKKKAEE---LKKAEEENKIKAaEEAKKAEEDKKK 1676

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  214 MEELQHAED----------MAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVREL 283
Cdd:PTZ00121 1677 AEEAKKAEEdekkaaealkKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK 1756

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 688616510  284 TDQIQARVEEDDPVMAAVNAKVEEWKSVLSGKDLE-ILEYQQMIRDLREKLRTAQMDSDKSNII 346
Cdd:PTZ00121 1757 KKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKrRMEVDKKIKDIFDNFANIIEGGKEGNLV 1820
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2391-2510 3.38e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 46.00  E-value: 3.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2391 KEKAEVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQRENENLKRtsevnvqeQLATLERDHEKLKSEYEKLKGKQ 2470
Cdd:COG2433   386 IEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEA--------ELEEKDERIERLERELSEARSEE 457

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 688616510 2471 EEQLNSRLEsktkgIEKIMMENERLRKEIKKEAEAAEKLR 2510
Cdd:COG2433   458 RREIRKDRE-----ISRLDREIERLERELEEERERIEELK 492
mukB PRK04863
chromosome partition protein MukB;
1135-1875 3.48e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.49  E-value: 3.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1135 EANLRIEVSKlrEVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQaesdeKALIAklhQHIVALQLSEttAISRLEAT 1214
Cdd:PRK04863  359 ELEERLEEQN--EVVEEADEQQEENEARAEAAEEEVDELKSQLADYQ-----QALDV---QQTRAIQYQQ--AVQALERA 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1215 NTRLQK--LEAQKLRD--EQKLDEQQQALWHARQEGHQRARHlrhtiQALRRQFSGALPLAQ-----------QEKFSNT 1279
Cdd:PRK04863  427 KQLCGLpdLTADNAEDwlEEFQAKEQEATEELLSLEQKLSVA-----QAAHSQFEQAYQLVRkiagevsrseaWDVAREL 501

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1280 MLHLQEDRARVREDAQIteeerrkaEGKAQELELKLKGLEELIATLKDAKGAQKVSewhkkLEDVRLLEMRQSrELNTQR 1359
Cdd:PRK04863  502 LRRLREQRHLAEQLQQL--------RMRLSELEQRLRQQQRAERLLAEFCKRLGKN-----LDDEDELEQLQE-ELEARL 567

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1360 EEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLER-------------QLDSYEKQQNEVLNTAQ--- 1423
Cdd:PRK04863  568 ESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARlreqsgeefedsqDVTEYMQQLLERERELTver 647

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1424 -KFEEATGSLPDPNQPLANQ---LDYALGKIKEHVRTILETKTTCKILEEKLKEKEAALWSSEQNVlsrdkVINELRLRL 1499
Cdd:PRK04863  648 dELAARKQALDEEIERLSQPggsEDPRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPARHAI-----VVPDLSDAA 722

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1500 PAAAEREKLLADLSKQEDS---------ESQPTLKVAHQTINNLQGRLDQKEEVlkkyqNLLGKA---------RQEQEE 1561
Cdd:PRK04863  723 EQLAGLEDCPEDLYLIEGDpdsfddsvfSVEELEKAVVVKIADRQWRYSRFPEV-----PLFGRAarekrieqlRAEREE 797

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1562 IAKRHEE------EVRALHQKLDVYMDTSLdrfkqtALELIKKPTitvptskhlVRLAEMEQTVAEQDNSLSSLSQKLKI 1635
Cdd:PRK04863  798 LAERYATlsfdvqKLQRLHQAFSRFIGSHL------AVAFEADPE---------AELRQLNRRRVELERALADHESQEQQ 862

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1636 VTQELDQQRQVTAAQAmEHAADMARLEDKHaaqmkgLSQEAEELRAQLIQMEKELHYLR------TELEAQKEANVRSPS 1709
Cdd:PRK04863  863 QRSQLEQAKEGLSALN-RLLPRLNLLADET------LADRVEEIREQLDEAEEAKRFVQqhgnalAQLEPIVSVLQSDPE 935

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1710 N--TMKNLVERLKNQLALKEKQLKALSKaLLELRAELTSQAEQQIITnaaqKEEALNVQqivdkqtkeLRACVRDLNEEL 1787
Cdd:PRK04863  936 QfeQLKQDYQQAQQTQRDAKQQAFALTE-VVQRRAHFSYEDAAEMLA----KNSDLNEK---------LRQRLEQAEQER 1001

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1788 QLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEAL--------EEHLNELKKKI-QRLS------SGLQA 1852
Cdd:PRK04863 1002 TRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLgvpadsgaEERARARRDELhARLSanrsrrNQLEK 1081

                         810       820
                  ....*....|....*....|...
gi 688616510 1853 QVESDGPTVDALQKKIRKLEHEL 1875
Cdd:PRK04863 1082 QLTFCEAEMDNLTKKLRKLERDY 1104
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1646-1852 3.58e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 3.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1646 VTAAQAMEHAADMARLEDKHAAqmkgLSQEAEELRAQLIQMEKELHYLRTELEAQKEANVRSpsntmknLVERLKNQLAL 1725
Cdd:COG4913   245 EDAREQIELLEPIRELAERYAA----ARERLAELEYLRAALRLWFAQRRLELLEAELEELRA-------ELARLEAELER 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1726 KEKQLKALSKALLELRAELTS-------QAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELqlaKDGVRAAK 1798
Cdd:COG4913   314 LEARLDALREELDELEAQIRGnggdrleQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEF---AALRAEAA 390

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 688616510 1799 ARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQA 1852
Cdd:COG4913   391 ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLA 444
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2421-2729 4.38e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 4.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2421 GLMKKVVEKVQRENENLKRTSEVnvQEQLATLERDHEKLKSEYEKLKGKQEEqLNSRLESKTKGIEKIMMENERLRKEIK 2500
Cdd:TIGR02169  692 SLQSELRRIENRLDELSQELSDA--SRKIGEIEKEIEQLEQEEEKLKERLEE-LEEDLSSLEQEIENVKSELKELEARIE 768

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2501 KEAEAAEKLRVAKASLEVAN--------EKLKAELEETHQRLllaqskGATLLGVDSKTWKSSVVTRLFENKMKGLESDI 2572
Cdd:TIGR02169  769 ELEEDLHKLEEALNDLEARLshsripeiQAELSKLEEEVSRI------EARLREIEQKLNRLTLEKEYLEKEIQELQEQR 842

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2573 AKKNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNvpveatTDEGLAREYQSVRLANKQLEREKAQLLRQIQRNE 2652
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES------RLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2653 VQLGTNKDGPGytELQEQIKAANNEKK-------------KLQDEVRKLTQELKHFDPTFF---EELEDLKFNYNLEVKK 2716
Cdd:TIGR02169  917 KRLSELKAKLE--ALEEELSEIEDPKGedeeipeeelsleDVQAELQRVEEEIRALEPVNMlaiQEYEEVLKRLDELKEK 994

                          330
                   ....*....|...
gi 688616510  2717 NIVLEEQLKKLSD 2729
Cdd:TIGR02169  995 RAKLEEERKAILE 1007
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
995-1395 4.53e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 4.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  995 ERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKM--YEH 1072
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPerLEE 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1073 LRNSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSVSKHISDAD--RKRITELEKTEANLRIEVSKLREVSD 1150
Cdd:COG4717   151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEelQQRLAELEEELEEAQEELEELEEELE 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1151 VAKMQVSALDARQQSREKEVESLRRQVL-----DYQAESDEKALIAKLHQHIVALQLSETTAISRLEATNT----RLQKL 1221
Cdd:COG4717   231 QLENELEAAALEERLKEARLLLLIAAALlallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGkeaeELQAL 310

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1222 EAQKLRDEQKLDEQQQALWHARQEGHQRARHLRHTIQALRRQFSGALPLAQQEKFSNTMLHLQEDRARVREDaqiTEEER 1301
Cdd:COG4717   311 PALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVE---DEEEL 387

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1302 RKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEE 1381
Cdd:COG4717   388 RAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEE 467

                         410
                  ....*....|....
gi 688616510 1382 ELVQQNNLLEERQL 1395
Cdd:COG4717   468 DGELAELLQELEEL 481
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2360-2704 6.69e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 6.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2360 ELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQRENENLKR 2439
Cdd:PRK03918  263 ELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2440 TSE--VNVQEQLATLERDHEklksEYEKLKGKQEEQLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAKASLE 2517
Cdd:PRK03918  343 LKKklKELEKRLEELEERHE----LYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK 418

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2518 VANEKLKAELEETHQRLLLAQSKGATLLGVDSKTWKSSvvtrlFENKMKGLESDIAKKNISISELKVQLKEAnEKLQATQ 2597
Cdd:PRK03918  419 KEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEE-----YTAELKRIEKELKEIEEKERKLRKELREL-EKVLKKE 492

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2598 HTVIQLKEQVELLKNVP-----VEATTDEGLAREYQSVRLANKQLEREKAQLLRQIQRNEvqlgtnkdgpgytELQEQIK 2672
Cdd:PRK03918  493 SELIKLKELAEQLKELEeklkkYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE-------------ELKKKLA 559

                         330       340       350
                  ....*....|....*....|....*....|..
gi 688616510 2673 AANNEKKKLQDEVRKLTQELKHFDPTFFEELE 2704
Cdd:PRK03918  560 ELEKKLDELEEELAELLKELEELGFESVEELE 591
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1722-1852 7.78e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 7.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1722 QLALKEKQLKALSKALLELRAELTS-QAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDGVRAAKAr 1800
Cdd:COG4913   611 KLAALEAELAELEEELAEAEERLEAlEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA- 689

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 688616510 1801 ensLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQA 1852
Cdd:COG4913   690 ---LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA 738
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1208-1386 7.78e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 7.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1208 ISRLEATNTRLQKLEAQ--KLRDEQKLDEQQQALWHARQEGH---QRARHLRHTIQALRRQfsgalpLAQQEKFSNTMLH 1282
Cdd:COG4913   616 EAELAELEEELAEAEERleALEAELDALQERREALQRLAEYSwdeIDVASAEREIAELEAE------LERLDASSDDLAA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1283 LQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGA--QKVSEWHKKLEDVRLLEMRQSRELNTQRE 1360
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaeDLARLELRALLEERFAAALGDAVERELRE 769

                         170       180
                  ....*....|....*....|....*.
gi 688616510 1361 EikyLKNCVAEQERTISGLEEELVQQ 1386
Cdd:COG4913   770 N---LEERIDALRARLNRAEEELERA 792
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2342-2613 7.82e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 7.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2342 QREHEFQKENLRLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVEKRLNHLRgsgrsgKTIPELEKTIg 2421
Cdd:COG1196   246 AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLE------ERRRELEERL- 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2422 lmkkvvEKVQRENENLKRTSEvNVQEQLATLERDHEKLKSEYEKLKGKQEEQLNSRLESKTKGIEKImmenERLRKEIKK 2501
Cdd:COG1196   319 ------EELEEELAELEEELE-ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE----EELEELAEE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2502 EAEAAEKLRVAKASLEVANEKLKAELEETHQRLLLAQSKGATLLGVDSKTWKSSVVTRLFENKMKGLESDIAKKNISISE 2581
Cdd:COG1196   388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270
                  ....*....|....*....|....*....|..
gi 688616510 2582 LKVQLKEANEKLQATQHTVIQLKEQVELLKNV 2613
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLEA 499
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 381-648 8.06e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.92  E-value: 8.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  381 ERNAMLIEELKRPLKKDkghssdhqrRLEDLSAKLQVAERKVleaqraAQLaeRDARDKDKELNDTLSRIRLyesgtDGL 460
Cdd:PRK05771   27 ELGVVHIEDLKEELSNE---------RLRKLRSLLTKLSEAL------DKL--RSYLPKLNPLREEKKKVSV-----KSL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  461 EAAISEIKECKNQIrvrDREIEGMIKEINQLEMKINNLLDENEDLrERLGlnpKEELDLSEFRRSKILKQ------RQYK 534
Cdd:PRK05771   85 EELIKDVEEELEKI---EKEIKELEEEISELENEIKELEQEIERL-EPWG---NFDLDLSLLLGFKYVSVfvgtvpEDKL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  535 AENQVLLKEIERLEEERLELKQRIRALVKDKGVTVVSNSLLDNSVEEKPVrslrPSSGSTDDEIkrknerlqkelSNKEK 614
Cdd:PRK05771  158 EELKLESDVENVEYISTDKGYVYVVVVVLKELSDEVEEELKKLGFERLEL----EEEGTPSELI-----------REIKE 222

                         250       260       270
                  ....*....|....*....|....*....|....
gi 688616510  615 ELELRRSESTQFKAKLNEMLNENKQLEQGMKEIL 648
Cdd:PRK05771  223 ELEEIEKERESLLEELKELAKKYLEELLALYEYL 256
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 68-738 8.82e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.96  E-value: 8.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510    68 EVVDSAGAEQARIENELKAKVLKLESELEmaqrvmggGDKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELAL 147
Cdd:TIGR00618  176 DQYTQLALMEFAKKKSLHGKAELLTLRSQ--------LLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQ 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   148 RAEEAEEKNRKlKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANL 227
Cdd:TIGR00618  248 KREAQEEQLKK-QQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   228 RSENEHLQK---NLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRK---DRDHAKLQVRELT-----DQIQARVEEDDP 296
Cdd:TIGR00618  327 LMKRAAHVKqqsSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQqhtLTQHIHTLQQQKTtltqkLQSLCKELDILQ 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   297 VMAAVNAKVEEWKSVLSGKDLEI---LEYQQMIRDLREKLRTAQMDSDKSNIIALQQVIYELcGAVQERDNQIKMLSEQV 373
Cdd:TIGR00618  407 REQATIDTRTSAFRDLQGQLAHAkkqQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSL-KEREQQLQTKEQIHLQE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   374 EQYTTEMERNAMLIEELKRPLKKDKGHSSDHQ-------------RRLEDLSAKLQVAERKV-----LEAQRAAQLAERD 435
Cdd:TIGR00618  486 TRKKAVVLARLLELQEEPCPLCGSCIHPNPARqdidnpgpltrrmQRGEQTYAQLETSEEDVyhqltSERKQRASLKEQM 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   436 ARDKDKELNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINN----LLDENEDLRERLGL 511
Cdd:TIGR00618  566 QEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLqdvrLHLQQCSQELALKL 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   512 NPKEELDLS---EFRRSKILKQRQYKAEnqvllkEIERLEEERLELKQRIRALVKDKGVTVVSNSLL---DNSVEE--KP 583
Cdd:TIGR00618  646 TALHALQLTltqERVREHALSIRVLPKE------LLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLrelETHIEEydRE 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   584 VRSLRPSSGSTDDEIKRKNERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTG 663
Cdd:TIGR00618  720 FNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTH 799

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616510   664 VSIPSLERLVNalEMKYSEGKFDASLHL----RTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEME 738
Cdd:TIGR00618  800 LLKTLEAEIGQ--EIPSDEDILNLQCETlvqeEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSD 876
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1687-2530 8.90e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.96  E-value: 8.90e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1687 EKELHYLRTELEAQKEANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQ 1766
Cdd:pfam02463  185 LAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1767 QIVDKQTKELRACvrdlNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRL 1846
Cdd:pfam02463  265 EKLAQVLKENKEE----EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEEL 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1847 ssglQAQVESDGPTVDALQKKIRKLEHELDRKSISEPADKRSTLKEDKSSKEEVVRWEEGKKWQARVDKMRNVLKEKERE 1926
Cdd:pfam02463  341 ----EKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQ 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1927 VDSQAKQLATmKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAELEQQIKVMKQQQALPRDAAM 2006
Cdd:pfam02463  417 LEDLLKEEKK-EELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2007 EDITNRNRYLEERLYSMESRLSKEPPSRPSDRHSTSPSQLSWSSKVRSMTFDV---------IEAEQTQSSLLNSTVVVT 2077
Cdd:pfam02463  496 EERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAvivevsataDEVEERQKLVRALTELPL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2078 EKEISVIEDKATQTSFRSIDMGTAEVNQDDENVAKNKIDLEQKALMKDDKTEQEESNKEKGSVEKDEEQPDETQRGQDVA 2157
Cdd:pfam02463  576 GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2158 VFEYAQEELKTNDEAEELESELTHREMMEKPLDEDQLEVENEETNAEEMLYSTmnQAELETPKVLLEGDEDYGQEPEELL 2237
Cdd:pfam02463  656 EGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQRE--KEELKKLKLEAEELLADRVQEAQDK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2238 KCECDPSAESKELDEEETALSNSTTFDAKLVSEQPAMEKNKSFTPEAGFNPNLSEVSTSRELNANTENDILGHLKAKVTR 2317
Cdd:pfam02463  734 INEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEE 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2318 LNDKEHSMKSKARKTSGRGSDTPSQR---EHEFQKENLRLSTENLELRFQLEQANKDLPRLKDQVSDLKEMCSVLKKEKA 2394
Cdd:pfam02463  814 AELLEEEQLLIEQEEKIKEEELEELAlelKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE 893

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2395 EVEKRLNHLRGSGRSGKTIPELEKTIGLMKKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKGKQEEQL 2474
Cdd:pfam02463  894 KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 688616510  2475 NSRLESKTKGIEKimmENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEET 2530
Cdd:pfam02463  974 KVNLMAIEEFEEK---EERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELF 1026
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1130-1406 8.95e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 8.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1130 ELEKTEANLRIEVSKLREVSDvakmQVSALDARQQSREKEVESLRRQVLDYQAESDEkaliaklhQHIVALQLSEttAIS 1209
Cdd:COG3096   355 DLEELTERLEEQEEVVEEAAE----QLAEAEARLEAAEEEVDSLKSQLADYQQALDV--------QQTRAIQYQQ--AVQ 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1210 RLEatntrlqklEAQKLRDEQKLDEQQQALWHAR-----QEGHQRARHLRHTI---QALRRQFSGALPLAQQekfsntmL 1281
Cdd:COG3096   421 ALE---------KARALCGLPDLTPENAEDYLAAfrakeQQATEEVLELEQKLsvaDAARRQFEKAYELVCK-------I 484

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1282 HLQEDRARVREDAQITEEERRKAE---GKAQELELKLKGLEELIATLKDAKGAQKvsEWHKK----LEDVRLLEMRQSrE 1354
Cdd:COG3096   485 AGEVERSQAWQTARELLRRYRSQQalaQRLQQLRAQLAELEQRLRQQQNAERLLE--EFCQRigqqLDAAEELEELLA-E 561

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 688616510 1355 LNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQREVQLER 1406
Cdd:COG3096   562 LEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALER 613
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 318-633 1.04e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 1.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   318 EILEYQQMIRDLREKLRTAQMDsdksnIIALQQVIYELCGAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKD 397
Cdd:TIGR02169  703 RLDELSQELSDASRKIGEIEKE-----IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL 777

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   398 KGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQlaERDARDKDKELNDTLSRIRLYESGTDGLEaaiSEIKECKNQIRVR 477
Cdd:TIGR02169  778 EEALNDLEARLSHSRIPEIQAELSKLEEEVSRI--EARLREIEQKLNRLTLEKEYLEKEIQELQ---EQRIDLKEQIKSI 852

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   478 DREIEGMIKEINQLEMKINNLLDENEDLRERLGLNPKEELDLSEFRRSKILKQRQYKAENQVLLKEIERLEEERLELKQR 557
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   558 IRALVKDK--GVTVVSNSLLDNSVEEK------PVRSLRPSSGSTDDEIKRKNERLqKELSNKEKELELRRSESTQFKAK 629
Cdd:TIGR02169  933 LSEIEDPKgeDEEIPEEELSLEDVQAElqrveeEIRALEPVNMLAIQEYEEVLKRL-DELKEKRAKLEEERKAILERIEE 1011


                   ....
gi 688616510   630 LNEM 633
Cdd:TIGR02169 1012 YEKK 1015
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1150-1927 1.05e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.83  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1150 DVAKMQVSALDARQQSREKEVESlRRQVLDYQAESDEKALIAKLHQHIVALQlsetTAISRLEATNTRLQKLEAQKLRDE 1229
Cdd:pfam12128  197 DVKSMIVAILEDDGVVPPKSRLN-RQQVEHWIRDIQAIAGIMKIRPEFTKLQ----QEFNTLESAELRLSHLHFGYKSDE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1230 QKLDEQQQALWHARQEGHQRARHLRHTIQALRRQFSGALPlAQQEKFSNTMLHLQ--EDRARVREDAQIteeERRKAEGK 1307
Cdd:pfam12128  272 TLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELS-AADAAVAKDRSELEalEDQHGAFLDADI---ETAAADQE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1308 -----AQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEE 1382
Cdd:pfam12128  348 qlpswQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQ 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1383 LVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEATGSLPDPNQPLANQL-------------DYALGK 1449
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVErlqselrqarkrrDQASEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1450 IKEHVRTILETKTTCKILEEKLK----------EKEAALWSSeqnvlSRDKVIN-ELRLRLPAAAErekLLADLSKQEDS 1518
Cdd:pfam12128  508 LRQASRRLEERQSALDELELQLFpqagtllhflRKEAPDWEQ-----SIGKVISpELLHRTDLDPE---VWDGSVGGELN 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1519 ESQPTLKVAHQTINNLQgrldQKEEVLKKYQNLLGKARQEQEEIAKRHEEEVRALHQKLD---VYMDTSLDRFKQTALEL 1595
Cdd:pfam12128  580 LYGVKLDLKRIDVPEWA----ASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEkasREETFARTALKNARLDL 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1596 IKKPTITVPTSKHLVRLAEMEQTVAEQdnSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAadMARLEDKHAAQmkglsqe 1675
Cdd:pfam12128  656 RRLFDEKQSEKDKKNKALAERKDSANE--RLNSLEAQLKQLDKKHQAWLEEQKEQKREAR--TEKQAYWQVVE------- 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1676 aEELRAQLIQMEKELHYLRTELEAQKEANVRSPSNTMKNL------VERLKNQLALKEKQLKALSK---ALLELRAELTS 1746
Cdd:pfam12128  725 -GALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLgvdpdvIAKLKREIRTLERKIERIAVrrqEVLRYFDWYQE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1747 QAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQ 1826
Cdd:pfam12128  804 TWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQ 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1827 SEKEALE--EHLNELKKKIQRLSsglqaqvesdgptvDALQKKIRKLEHELDRKSISEPADKRSTLKEDKSSK-EEVVRW 1903
Cdd:pfam12128  884 AQGSIGErlAQLEDLKLKRDYLS--------------ESVKKYVEHFKNVIADHSGSGLAETWESLREEDHYQnDKGIRL 949

                          810       820
                   ....*....|....*....|....
gi 688616510  1904 EEGKKWQARVDKMRNVLKEKEREV 1927
Cdd:pfam12128  950 LDYRKLVPYLEQWFDVRVPQSIMV 973
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 110-472 1.11e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.65  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   110 LRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRES 189
Cdd:TIGR00606  693 LQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQET 772

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   190 L----------------------QTKEESNEIQRR------------LTKANQQLYQCMEELQHAEDMAANLRSENEHLQ 235
Cdd:TIGR00606  773 LlgtimpeeesakvcltdvtimeRFQMELKDVERKiaqqaaklqgsdLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLI 852

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   236 KNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGK 315
Cdd:TIGR00606  853 QDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSK 932

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   316 DLEILEYQQMIRDLREKLRTA----------------QMDSDKSNIIALQQVIYELCGAVQERDNqiKMLSEQVEQYTTE 379
Cdd:TIGR00606  933 ETSNKKAQDKVNDIKEKVKNIhgymkdienkiqdgkdDYLKQKETELNTVNAQLEECEKHQEKIN--EDMRLMRQDIDTQ 1010

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   380 MERNAMLIEELKRPLKKDKGHSSDHQRRLEDLsaklQVAERKVLEAQRAAQLAERDARDKDKELNDTLSRIRLYESGTDG 459
Cdd:TIGR00606 1011 KIQERWLQDNLTLRKRENELKEVEEELKQHLK----EMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKH 1086

                          410
                   ....*....|...
gi 688616510   460 LEAAISEiKECKN 472
Cdd:TIGR00606 1087 FKKELRE-PQFRD 1098
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 108-210 1.22e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 44.56  E-value: 1.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  108 HFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAeQR 187
Cdd:PRK11448  145 HALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERKQKRKEI-TD 223

                          90       100
                  ....*....|....*....|...
gi 688616510  188 ESLQTKEESNEIQRRLTkaNQQL 210
Cdd:PRK11448  224 QAAKRLELSEEETRILI--DQQL 244
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1529-1950 1.32e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1529 QTINNLQGRLDQKEEVLKKYQNLLGKARQEQEEIA------KRHEEEVRALHQKLDVYMDtsLDRFKQTALELIKKPTit 1602
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEeleaelEELREELEKLEKLLQLLPL--YQELEALEAELAELPE-- 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1603 vptskHLVRLAEMEQTVAEQDNSLSSLSQKLKIVTQELDQQRQVTAAQAMEHAADMARLEDKHAAQMKGLSQEAEELRAQ 1682
Cdd:COG4717   147 -----RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEE 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1683 LIQMEKELHYLRTELEAQKEAN-----------------VRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELT 1745
Cdd:COG4717   222 LEELEEELEQLENELEAAALEErlkearlllliaaallaLLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLG 301

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1746 SQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDgVRAAKARENSLKEDLETLNKDLQRSQKSQNKL 1825
Cdd:COG4717   302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEE-LQELLREAEELEEELQLEELEQEIAALLAEAG 380

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1826 QSEKEALEEHL------NELKKKIQRLSSGLQAQVESDGPTVDALQKKIRKLEHELDRKSISEPADKRSTLKEDKSS-KE 1898
Cdd:COG4717   381 VEDEEELRAALeqaeeyQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAElEA 460

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 688616510 1899 EVVRWEEGK---KWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVS 1950
Cdd:COG4717   461 ELEQLEEDGelaELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLP 515
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 145-375 1.46e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  145 LALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEfyrKEAEQRESLQtkEESNEIQRRLTKANQQLYQCMEELQHAEDMA 224
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELA---ALKKEEKALL--KQLAALERRIAALARRIRALEQELAALEAEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  225 ANLRSENEHLQKNLEESVKEMEKM------TDEYNKMKIAVQQTDAiMDQLRKDRDHAKL--QVRELTDQIQARVEEDDP 296
Cdd:COG4942    86 AELEKEIAELRAELEAQKEELAELlralyrLGRQPPLALLLSPEDF-LDAVRRLQYLKYLapARREQAEELRADLAELAA 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616510  297 VMAAVNAKVEEWKSVLSGKDLEILEYQQMIRDlreklRTAQMDSDKSNIIALQQVIYELCGAVQERDNQIKMLSEQVEQ 375
Cdd:COG4942   165 LRAELEAERAELEALLAELEEERAALEALKAE-----RQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 75-321 1.62e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 44.27  E-value: 1.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   75 AEQARieneLKAKVlkleSELEMAQRVMGGgdkhflRDEIRQLESHL-----ERKEKEVTQLEKEMGKERKSNEELAL-R 148
Cdd:PRK10929  180 AESAA----LKALV----DELELAQLSANN------RQELARLRSELakkrsQQLDAYLQALRNQLNSQRQREAERALeS 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  149 AEEAEEKNRKLKREIKQLTRKNEQLQQDIefyrKEAEQRESLQTKEesneiQRRLTKANQQLYQCMEELQhaeDMAANLR 228
Cdd:PRK10929  246 TELLAEQSGDLPKSIVAQFKINRELSQAL----NQQAQRMDLIASQ-----QRQAASQTLQVRQALNTLR---EQSQWLG 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  229 SEN---EHLQKNLEEsVKEMEKMtdeynkmkiavQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVN--- 302
Cdd:PRK10929  314 VSNalgEALRAQVAR-LPEMPKP-----------QQLDTEMAQLRVQRLRYEDLLNKQPQLRQIRQADGQPLTAEQNril 381

                         250       260
                  ....*....|....*....|....
gi 688616510  303 -----AKVEEWKSVLSGKDLEILE 321
Cdd:PRK10929  382 daqlrTQRELLNSLLSGGDTLILE 405
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
995-1224 1.88e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  995 ERIDSINKELEISKEKLHTLEQAFEnisttggeiimdkatkavANSEIVSVSRRITTLEmkELNERQRAEHAQKMYEHLR 1074
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEPIRE------------------LAERYAAARERLAELE--YLRAALRLWFAQRRLELLE 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1075 NSLKQVEERNFELETKFAELTKLNLEAQRIERELRDELADSvskhisdaDRKRITELEKTEANLRIEVSKLREVSDVAKM 1154
Cdd:COG4913   295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGN--------GGDRLEQLEREIERLERELEERERRRARLEA 366

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1155 QVSALDARQQSREKEVESLRRQVldyqaesdeKALIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQ 1224
Cdd:COG4913   367 LLAALGLPLPASAEEFAALRAEA---------AALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1666-1846 2.07e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 2.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1666 AAQMKGLSQEAEELRAQLIQMEKELHYLRTELEAQKE-----ANVRSPSNTMKNlVERLKNQLALKEKQLKALSKALLEL 1740
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQErrealQRLAEYSWDEID-VASAEREIAELEAELERLDASSDDL 687

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1741 RaeltsQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENS-----LKEDLETLNKDL 1815
Cdd:COG4913   688 A-----ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLelralLEERFAAALGDA 762

                         170       180       190
                  ....*....|....*....|....*....|.
gi 688616510 1816 QRSQKSQNkLQSEKEALEEHLNELKKKIQRL 1846
Cdd:COG4913   763 VERELREN-LEERIDALRARLNRAEEELERA 792
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1152-1397 2.49e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1152 AKMQVSALDARQQSREKEVESLRRQVLDYQAEsdekalIAKLHQHIVALQLSETTAISRLEATNTRLQKLEAQKLRDEQK 1231
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQ------LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1232 LDEQQQALwhARQEGHQRARHLRHTIQALRRQFSGALPLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQEL 1311
Cdd:COG4942    99 LEAQKEEL--AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1312 ELKLKGLEELIATLKDAKGAQKvsewhKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLE 1391
Cdd:COG4942   177 EALLAELEEERAALEALKAERQ-----KLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251


                  ....*.
gi 688616510 1392 ERQLIW 1397
Cdd:COG4942   252 KGKLPW 257
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2491-2730 2.51e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 2.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2491 ENERLRKEIKKEAEAAEKLRVAKASLEVANEKLKAELE------ETHQRLLLAQSKGATLLGVDSKTWKSSVVTRLFENk 2564
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEqlrkelEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL- 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2565 mKGLESDIAKKNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNVPVEATTDEG-LAREYQSVRLANKQLEREKAQ 2643
Cdd:TIGR02168  757 -TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTlLNEEAANLRERLESLERRIAA 835

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2644 LLRQIQRNEVQLGtnkdgpgytELQEQIKAANNEKKKLQDEVRKLTQELKHFD---PTFFEELEDLKFNYNLEVKKNIVL 2720
Cdd:TIGR02168  836 TERRLEDLEEQIE---------ELSEDIESLAAEIEELEELIEELESELEALLnerASLEEALALLRSELEELSEELREL 906

                          250
                   ....*....|
gi 688616510  2721 EEQLKKLSDQ 2730
Cdd:TIGR02168  907 ESKRSELRRE 916
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 691-842 2.52e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 2.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  691 LRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSKS---TGSSIPHKTLAL----PEEMTpTS 763
Cdd:COG3883    42 LQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAlyrSGGSVSYLDVLLgsesFSDFL-DR 120

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688616510  764 AEAINALNEYTVQLLQEIKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQRE 842
Cdd:COG3883   121 LSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLA 199
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 118-314 2.68e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 2.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  118 ESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRE--------S 189
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERReelgerarA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  190 LQTKEESN-------------------EIQRRLTKANQQLyqcMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTD 250
Cdd:COG3883    95 LYRSGGSVsyldvllgsesfsdfldrlSALSKIADADADL---LEELKADKAELEAKKAELEAKLAELEALKAELEAAKA 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 688616510  251 EYNKmkiAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSG 314
Cdd:COG3883   172 ELEA---QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 126-915 2.69e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.42  E-value: 2.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   126 KEVTQLEKEMGKERKSNEELALRAEE---AEEKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRR 202
Cdd:pfam02463  142 GKIEIIAMMKPERRLEIEEEAAGSRLkrkKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   203 LTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQqtdaimdQLRKDRDHAKLQVRE 282
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEK-------EKKLQEEELKLLAKE 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   283 LTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQMDSDKSNIIALQQVIYELcgAVQER 362
Cdd:pfam02463  295 EEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEK--LEQLE 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   363 DNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVLEAQRAAQLAERDARDKDKE 442
Cdd:pfam02463  373 EELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEE 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   443 LNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRERLGLNPKEELDLSEF 522
Cdd:pfam02463  453 LEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLG 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   523 RRSKILKQRQYKAENQVLLKEIERLEEERLELKQRIRALVKDKGVTVVSnslLDNSVEEKPVRSLRPSSGSTDDEIKRKN 602
Cdd:pfam02463  533 DLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLR---LLIPKLKLPLKSIAVLEIDPILNLAQLD 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   603 ERLQKELSNKEKELELRRSESTQFKAKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGVSIPSLERLVNALEMKYSE 682
Cdd:pfam02463  610 KATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESEL 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   683 GKFDASLHLRTQVDQLTGRNEELRQEMKTARE-EAANTLSQLTKANEKIARLESEMESMSKSTGSSIPHKTLALPEEMTP 761
Cdd:pfam02463  690 AKEEILRRQLEIKKKEQREKEELKKLKLEAEElLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSEL 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   762 TSAEAINALNE-YTVQLLQEIKNKGDSIEQLGSALEEYKRKFAVIRHQQGLLYKEHQSERESWQKERDSFAELKSKLEEQ 840
Cdd:pfam02463  770 SLKEKELAEEReKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLE 849

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 688616510   841 REVDAVKIKEYNHLLETLEKDPSEIRREMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQ 915
Cdd:pfam02463  850 KLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIK 924
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
117-256 2.77e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 43.31  E-value: 2.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  117 LESHLERKEKEVtqLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEfyrkeaEQRESLQtkees 196
Cdd:COG2433   378 IEEALEELIEKE--LPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELE------EKDERIE----- 444

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  197 nEIQRRLTKANQQLYQCMEELQHAEdmaaNLRSENEHLQKNLEESVKEMEKMTDEYNKMK 256
Cdd:COG2433   445 -RLERELSEARSEERREIRKDREIS----RLDREIERLERELEEERERIEELKRKLERLK 499
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 812-1452 3.20e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.03  E-value: 3.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   812 LYKEHQSERESWQKERDSFAELKSKLEEQREVDavkikeynhlleTLEKDPSEIRREMAETGRKIVVLRVNEKCLTRR-- 889
Cdd:TIGR00618  224 LEKELKHLREALQQTQQSHAYLTQKREAQEEQL------------KKQQLLKQLRARIEELRAQEAVLEETQERINRArk 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   890 YTTLLELEQHLRKENAKLKEDFTQMQAAVTERIGYLQRFKemaafkmASLQKSLDVSVPASELERANKQYTELTIKYRNL 969
Cdd:TIGR00618  292 AAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRA-------AHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVA 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   970 LQKDNHLVQKTTSLEHLETenmsLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKATKAVANSEIVSVSRRI 1049
Cdd:TIGR00618  365 TSIREISCQQHTLTQHIHT----LQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1050 TTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELET-------KFAELTKLNLEAQRIERELRDEL----ADSVSK 1118
Cdd:TIGR00618  441 ELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQihlqetrKKAVVLARLLELQEEPCPLCGSCihpnPARQDI 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1119 HISDADRKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDEKALIAKLHQHIV 1198
Cdd:TIGR00618  521 DNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLT 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1199 ALQLSETtaISRLEATNTRLQKLEAQ------KLRDEQKLDEQQQALWHARQEGHQRARHlRHTIQALRRQFSGALPLAQ 1272
Cdd:TIGR00618  601 EKLSEAE--DMLACEQHALLRKLQPEqdlqdvRLHLQQCSQELALKLTALHALQLTLTQE-RVREHALSIRVLPKELLAS 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1273 QEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKDAKGAQKVSEWHKKLEdvrllEMRQS 1352
Cdd:TIGR00618  678 RQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKE-----LMHQA 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1353 RELNTQREEIKYLKN---CVAEQERT-ISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLNTAQKFEEA 1428
Cdd:TIGR00618  753 RTVLKARTEAHFNNNeevTAALQTGAeLSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQ 832

                          650       660
                   ....*....|....*....|....
gi 688616510  1429 TGSLPDPNQPLANQLDYALGKIKE 1452
Cdd:TIGR00618  833 FLSRLEEKSATLGEITHQLLKYEE 856
PRK11281 PRK11281
mechanosensitive channel MscK;
137-354 3.42e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.98  E-value: 3.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  137 KERKSNEELALRAEEAEEKNRKLKREIKQLTRKNeqlqqdiefyrkEAEQRESLQtKEESNEIQRRLTKANQQLYQCMEE 216
Cdd:PRK11281   77 RQKEETEQLKQQLAQAPAKLRQAQAELEALKDDN------------DEETRETLS-TLSLRQLESRLAQTLDQLQNAQND 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  217 LQHAEDMAANLRSENEHLQKNLEEsvkemekmtdeynkmkiAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARveeddp 296
Cdd:PRK11281  144 LAEYNSQLVSLQTQPERAQAALYA-----------------NSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAE------ 200

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 688616510  297 vMAAVNAKVEEWKSVLSGKDLEILEYQQmIRDlrekLRTAQMDSDKSNIIALQQVIYE 354
Cdd:PRK11281  201 -QALLNAQNDLQRKSLEGNTQLQDLLQK-QRD----YLTARIQRLEHQLQLLQEAINS 252
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1611-2019 3.48e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 3.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1611 RLAEMEQTVAEQDNSLSSLSQKLKIvtQELDQQRQVTAAQAMEHAADMARLEDKHAaQMKGLSQEAEELRAQLIQMEKEL 1690
Cdd:COG4717   103 ELEELEAELEELREELEKLEKLLQL--LPLYQELEALEAELAELPERLEELEERLE-ELRELEEELEELEAELAELQEEL 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1691 HYLRTELEAQKEANVRSPSNTMKNL---VERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQ 1767
Cdd:COG4717   180 EELLEQLSLATEEELQDLAEELEELqqrLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALL 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1768 IVDKQTKELRACVRDLNEELQLAkdgVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLS 1847
Cdd:COG4717   260 ALLGLGGSLLSLILTIAGVLFLV---LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSP 336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1848 SGLQAQVEsDGPTVDALQKKIRKLEHELDRKSISEpaDKRSTLKEDKSSKEE-----VVRWEEGKKWQARVDKMRNVLKE 1922
Cdd:COG4717   337 EELLELLD-RIEELQELLREAEELEEELQLEELEQ--EIAALLAEAGVEDEEelraaLEQAEEYQELKEELEELEEQLEE 413

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1923 KEREVDSQAKQLAtmkelYSRLEQEKVSLQKKLKgrgvtadqvvgartlEADKEIEELHKRNAELEQQIKVMKQQQALPR 2002
Cdd:COG4717   414 LLGELEELLEALD-----EEELEEELEELEEELE---------------ELEEELEELREELAELEAELEQLEEDGELAE 473

                         410
                  ....*....|....*...
gi 688616510 2003 -DAAMEDITNRNRYLEER 2019
Cdd:COG4717   474 lLQELEELKAELRELAEE 491
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 113-254 3.69e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 3.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  113 EIRQLESHLERKEKEVTQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFYRKeAEQRESLQT 192
Cdd:COG1579    18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN-NKEYEALQK 96

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 688616510  193 KEESNEiqRRLTKANQQLYQCMEELQHAEDMAANLRSENEHLQKNLEESVKEMEKMTDEYNK 254
Cdd:COG1579    97 EIESLK--RRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA 156
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1770-1999 3.82e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 3.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1770 DKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSG 1849
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1850 LQAQvESDGPTVDALqkkirkleheLDRKSISEPADKRSTLKEDKSSKEEVVrwEEGKKWQARVDKMRNVLKEKEREVDS 1929
Cdd:COG3883    95 LYRS-GGSVSYLDVL----------LGSESFSDFLDRLSALSKIADADADLL--EELKADKAELEAKKAELEAKLAELEA 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1930 QAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAELEQQIKVMKQQQA 1999
Cdd:COG3883   162 LKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
PRK12704 PRK12704
phosphodiesterase; Provisional
 2424-2529 3.85e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 3.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2424 KKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKGKQEEQLNSR---LESKTKGIEKIMMENERLRKEIK 2500
Cdd:PRK12704   41 KRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKeenLDRKLELLEKREEELEKKEKELE 120

                          90       100
                  ....*....|....*....|....*....
gi 688616510 2501 KEAEAAEKLrvaKASLEVANEKLKAELEE 2529
Cdd:PRK12704  121 QKQQELEKK---EEELEELIEEQLQELER 146
TMCO5 pfam14992
TMCO5 family; The TMCO5 family includes human transmembrane and coiled-coil domain-containing ...
 129-252 3.95e-03

TMCO5 family; The TMCO5 family includes human transmembrane and coiled-coil domain-containing proteins 5A and 5B.


Pssm-ID: 464427 [Multi-domain]  Cd Length: 278  Bit Score: 42.01  E-value: 3.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   129 TQLEKEMGKERKSNEELALRAEEAEEKNRKLKREIKQlTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEiqrRLTKANQ 208
Cdd:pfam14992    6 SDLEKDLQRLDEANQVLLLKIQEKEEEIQSLEREITL-TRSLAEDEEREELNFTIMEKEDALQELELETA---KLEKKNE 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   209 QLYQCMEELQHAEDMA--ANLRSENEHLQKNLEESV--------------KEMEKMTDEY 252
Cdd:pfam14992   82 ILVKSVMELQRKLSRKsdKNTGLEQETLKQMLEELKvklqqseescadqeKELAKVESDY 141
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1739-1885 4.00e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.96  E-value: 4.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1739 ELRAELtSQAEQQIITnAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKdgvRAAKARENSLKEDLETLNkDLQRS 1818
Cdd:COG1566    80 DLQAAL-AQAEAQLAA-AEAQLARLEAELGAEAEIAAAEAQLAAAQAQLDLAQ---RELERYQALYKKGAVSQQ-ELDEA 153

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688616510 1819 QKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQVEsdgptVDALQKKIRKLEHELDRKSISEPAD 1885
Cdd:COG1566   154 RAALDAAQAQLEAAQAQLAQAQAGLREEEELAAAQAQ-----VAQAEAALAQAELNLARTTIRAPVD 215
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 690-1319 4.20e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 4.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  690 HLRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSkstgssiphktlalpeemtptsaEAINA 769
Cdd:COG1196   236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ-----------------------AEEYE 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  770 LNEYTVQLLQEIKNKGDSIEQLGSALEEYKRkfavirhqqgllykehqsERESWQKERDSFAELKSKLEEQREVDAVKIK 849
Cdd:COG1196   293 LLAELARLEQDIARLEERRRELEERLEELEE------------------ELAELEEELEELEEELEELEEELEEAEEELE 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  850 EYNHLLETLEKDPSEIRREMAETGRKIVvlrvnekcltRRYTTLLELEQHLRKENAKLKEDFTQMQAAVTERIGYLQRFK 929
Cdd:COG1196   355 EAEAELAEAEEALLEAEAELAEAEEELE----------ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE 424

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  930 EMAAFKMASLQKSLDVSVPASELERAnkqyteltikyrnLLQKDNHLVQKTTSLEHLETENMSLRERIDSINKELEISKE 1009
Cdd:COG1196   425 ELEEALAELEEEEEEEEEALEEAAEE-------------EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1010 KLHTLEQAFENISTTGGEIImdKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELET 1089
Cdd:COG1196   492 RLLLLLEAEADYEGFLEGVK--AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1090 KFAELTKLNLEAQRIERELRDELADSVskhISDADRKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQSREKE 1169
Cdd:COG1196   570 KAGRATFLPLDKIRARAALAAALARGA---IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL 646

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1170 VESLRRQVLDYQAESDEKALIAKlhqhivalqlsETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHARQEGHQR 1249
Cdd:COG1196   647 REVTLEGEGGSAGGSLTGGSRRE-----------LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1250 ARHLRHTIQALRRQFsgalpLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLE 1319
Cdd:COG1196   716 RLEEELEEEALEEQL-----EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1667-1885 4.42e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.58  E-value: 4.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1667 AQMKGLSQE---AEELRAQLIQMEKEL-----------HYLRTELEAQKEANVrspsnTMKNLVERLK----------NQ 1722
Cdd:PLN02939  184 ARIKLAAQEkihVEILEEQLEKLRNELlirgateglcvHSLSKELDVLKEENM-----LLKDDIQFLKaelievaeteER 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1723 LALKEKQLKALSKALLELRAELTSqAEQQIITNAAQKEEAL-----NVQQIVDKQTK--ELRACVRDLNEELQLAKDGVR 1795
Cdd:PLN02939  259 VFKLEKERSLLDASLRELESKFIV-AQEDVSKLSPLQYDCWwekveNLQDLLDRATNqvEKAALVLDQNQDLRDKVDKLE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1796 AAKARENSLKEDLETLnkDLqrsqksqnkLQSEKEALEEHLnelkkkiQRLSSGLQAQVESDGPTVDALQKKIRKLEHEL 1875
Cdd:PLN02939  338 ASLKEANVSKFSSYKV--EL---------LQQKLKLLEERL-------QASDHEIHSYIQLYQESIKEFQDTLSKLKEES 399

                         250
                  ....*....|
gi 688616510 1876 DRKSISEPAD 1885
Cdd:PLN02939  400 KKRSLEHPAD 409
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1763-2017 4.63e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 4.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1763 LNVQQIVDKQTKELRACVRDLNEELQLAKDGV---RAAKARENSLKEDLETLNKdlQRSQKSQNKLQSEKEALEEHLNEL 1839
Cdd:PRK05771   28 LGVVHIEDLKEELSNERLRKLRSLLTKLSEALdklRSYLPKLNPLREEKKKVSV--KSLEELIKDVEEELEKIEKEIKEL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1840 KKKIQRLSSglqaqvesdgptvdalqkKIRKLEHELDR----KSIS-EPADKRS---------TLKEDKSSKEEVVrWEE 1905
Cdd:PRK05771  106 EEEISELEN------------------EIKELEQEIERlepwGNFDlDLSLLLGfkyvsvfvgTVPEDKLEELKLE-SDV 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1906 GKKWQARVDKMRN-----VLKEKEREVDSQAKQL----------ATMKELYSRLEQEKVSLQKKLKgrgvtadqvvgart 1970
Cdd:PRK05771  167 ENVEYISTDKGYVyvvvvVLKELSDEVEEELKKLgferleleeeGTPSELIREIKEELEEIEKERE-------------- 232

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 688616510 1971 lEADKEIEELHKRNAELEQQIK-----VMKQQQALPRDAamedITNRNRYLE 2017
Cdd:PRK05771  233 -SLLEELKELAKKYLEELLALYeyleiELERAEALSKFL----KTDKTFAIE 279
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2415-2691 4.68e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 4.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2415 ELEKTIGLMKKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKlkGKQEEQLNSRLESKTKGIEKIMMENER 2494
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL--LAELARLEQDIARLEERRRELEERLEE 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2495 LRKEIKKEAEAAEKLRVAKASLEVANEKLKAELEETHQRLLLAQSKGATLlgvdsktwkssvvtrlfENKMKGLESDIAK 2574
Cdd:COG1196   321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA-----------------EAELAEAEEELEE 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2575 KNISISELKVQLKEANEKLQATQHTVIQLKEQVELLKNvpvEATTDEGLAREYQSVRLANKQLEREKAQLLRQIQRNEVQ 2654
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 688616510 2655 LGTNKDGPGYTELQEQIKAANNEKKKLQDEVRKLTQE 2691
Cdd:COG1196   461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 789-1583 4.68e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.65  E-value: 4.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   789 EQLGSALEEYKRKFAVIRHQQGLLYKEH--QSERESWQKERDSFAELKSKLEEQREVDAVKIKEYNHLLETLEKDPSEIR 866
Cdd:pfam02463  213 YQLKEKLELEEEYLLYLDYLKLNEERIDllQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   867 REMAETGRKIVVLRVNEKCLTRRYTTLLELEQHLRKENAKLKEDFTQMQAAVTERIGYLQRFKEMAAFKMASLQKSLDV- 945
Cdd:pfam02463  293 KEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLe 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   946 -SVPASELERANKQYTELTIKYRNLLQKDNHLVQKTTSLEHLETENMSLRERIdsiNKELEISKEKLHTLEQAFENISTT 1024
Cdd:pfam02463  373 eELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEK---KEELEILEEEEESIELKQGKLTEE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1025 GGEIIMDKATKAVANSEIVSVSRRITTLEMKELNERQRAEHAQKMYEHLRNSLKQVEERNFELETKFAELTKLNLEAQRI 1104
Cdd:pfam02463  450 KEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHG 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1105 ERELRDELADSVSKHISDAD-------------------RKRITELEKTEANLRIEVSKLREVSDVAKMQVSALDARQQS 1165
Cdd:pfam02463  530 RLGDLGVAVENYKVAISTAVivevsatadeveerqklvrALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLD 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1166 REKEVESLRRQVLDYQAESDEKALIAKLHQHIVALQ--LSETTAISRLEATNTRLQKLEAQKLRDEQKLDEQQQALWHAR 1243
Cdd:pfam02463  610 KATLEADEDDKRAKVVEGILKDTELTKLKESAKAKEsgLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESEL 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1244 QEGHQRARHLRHTIQALRRQFSGALPLAQQEKFSNTMLHLQEDRARVREDAQITEEERRKAE--GKAQELELKLKGLEEL 1321
Cdd:pfam02463  690 AKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEeeKSRLKKEEKEEEKSEL 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1322 IATLKDAKGAQKVSEWHKKLEDVRLLEMRQSRELNTQREEIKYLKNCVAEQERTISGLEEELVQQNNLLEERQLIWDQRE 1401
Cdd:pfam02463  770 SLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLE 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1402 VQLERQLDSYEKQQNEVLNTAQKfEEATGSLPDPNQPLANQLDYALGKIKEHvrtILETKTTCKILEEKlKEKEAALWSS 1481
Cdd:pfam02463  850 KLAEEELERLEEEITKEELLQEL-LLKEEELEEQKLKDELESKEEKEKEEKK---ELEEESQKLNLLEE-KENEIEERIK 924

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  1482 EQNVLSRDKVINELRLRLPAAAEREKLLADLSKQEDSESQPTLKVAHQTINNLqGRLDQKEEVLKKYQNLLGKARQEQEE 1561
Cdd:pfam02463  925 EEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNL-MAIEEFEEKEERYNKDELEKERLEEE 1003

                          810       820
                   ....*....|....*....|..
gi 688616510  1562 IAKRHEEEVRALHQKLDVYMDT 1583
Cdd:pfam02463 1004 KKKLIRAIIEETCQRLKEFLEL 1025
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 106-519 5.56e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 5.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   106 DKHFLRDEIRQLESHLERKEKEVTQLEKEMGKERKSNE---ELALRAEEAEEKNRKLKREIKQLTRKNEQLQQDIEFyrk 182
Cdd:TIGR04523  174 ELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISN--- 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   183 eaEQRESLQTKEESNEIQRRLTKANQQLYQCMEELQHAEDMAANLRSE------------NEHLQKNLEESVKEMEKMTD 250
Cdd:TIGR04523  251 --TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEisdlnnqkeqdwNKELKSELKNQEKKLEEIQN 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   251 EYNKMKIAVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMAAVNAKVEEWKSVLSGK---DLEILEYQQMIR 327
Cdd:TIGR04523  329 QISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQIndlESKIQNQEKLNQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   328 DLREKLRTAQMDSDKsniiaLQQVIYELCGAVQERDNQIKMLSEQVEQYTTEMERNAMLIEELKRPLKKDKGHSSDHQRR 407
Cdd:TIGR04523  409 QKDEQIKKLQQEKEL-----LEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   408 LEDLSAKLQVAERKVLEAQRAAQLAERDARDKDKELNDTLSRIRLYESGTDGLEAAISEIKECKNQIRVR------DREI 481
Cdd:TIGR04523  484 LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFElkkenlEKEI 563

                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 688616510   482 EGMIKEINQLEMKINNLLDENEDLRERLGLNPKEELDL 519
Cdd:TIGR04523  564 DEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDL 601
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 1712-2043 6.01e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 42.34  E-value: 6.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1712 MKNLVERLKNQL----ALKEKQLKALSKAllelRAELTSQAEQQIIT---NAAQKEEALNVQQIVDKQTKELRACVRDLN 1784
Cdd:PTZ00108 1004 LERELARLSNKVrfikHVINGELVITNAK----KKDLVKELKKLGYVrfkDIIKKKSEKITAEEEEGAEEDDEADDEDDE 1079

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1785 EELQLAKDGVRAAKARENSL-KEDLETLNKDLQRSQKSQNKLQSE-------------KEALEEHLNELKKKIQRLSSGL 1850
Cdd:PTZ00108 1080 EELGAAVSYDYLLSMPIWSLtKEKVEKLNAELEKKEKELEKLKNTtpkdmwledldkfEEALEEQEEVEEKEIAKEQRLK 1159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1851 QAQVESDGPtvdaLQKKIRKLEHELDRKSISEPADKRSTLKEDKSSKEEVVRweegKKWQARVDKMRNVLKEKEREVDSQ 1930
Cdd:PTZ00108 1160 SKTKGKASK----LRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKR----KLDDKPDNKKSNSSGSDQEDDEEQ 1231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1931 AKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHKRNAELEQQIKVMKQQQALPRDAAMEDIT 2010
Cdd:PTZ00108 1232 KTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVK 1311

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 688616510 2011 NRNRYL--------EERLYSMESRLSKEPPSRPSDRHSTSP 2043
Cdd:PTZ00108 1312 KRLEGSlaalkkkkKSEKKTARKKKSKTRVKQASASQSSRL 1352
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
82-279 6.18e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 6.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   82 NELKAKVLKLESELEMAQRvmgggdkhfLRDEIRQLESHLERKEKEVTQLEKEMGKER-KSNEELALRAEEAE------- 153
Cdd:PRK03918  535 IKLKGEIKSLKKELEKLEE---------LKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEpfyneyl 605

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  154 -------------EKNRKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESLQTKEESNEIQRRLTKANQQLYQCMEELQHA 220
Cdd:PRK03918  606 elkdaekelereeKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEEL 685

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 688616510  221 EDmaanLRSENEHLQKNLEESVKEMEKMTDEYNKMKIAVQQTDAIMDQLRKDRDHAKLQ 279
Cdd:PRK03918  686 EK----RREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKER 740
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1638-1820 6.34e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 6.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1638 QELDQQRQVTAAQAMEHAADMARLEDKHAA--QMKGLSQEAEELRAQLIQMEkELHYLRTELEAQKEAnVRSPSNTmknl 1715
Cdd:COG4913   613 AALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVA-SAEREIAELEAELER-LDASSDD---- 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1716 VERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQIVDKQTKELRAcvrDLNEELQLAKDGVR 1795
Cdd:COG4913   687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA---LLEERFAAALGDAV 763

                         170       180
                  ....*....|....*....|....*
gi 688616510 1796 AAKARENsLKEDLETLNKDLQRSQK 1820
Cdd:COG4913   764 ERELREN-LEERIDALRARLNRAEE 787
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1702-1877 6.76e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 6.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1702 EANVRSPSNTMKNLVERLKNQLALKEKQLKALSKALLELRAELTSQAEQQIITNAAQKEEALNVQQI-VDKQTKELRACV 1780
Cdd:COG3206   163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAeARAELAEAEARL 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1781 RDLNEELQLAKDGVRAAKA--RENSLKEDLETLNKDL----QRSQKSQNKLQSEKEALEEHLNELKKKIQRLSSGLQAQV 1854
Cdd:COG3206   243 AALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELaelsARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAEL 322

                         170       180
                  ....*....|....*....|...
gi 688616510 1855 ESDGPTVDALQKKIRKLEHELDR 1877
Cdd:COG3206   323 EALQAREASLQAQLAQLEARLAE 345
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
984-1186 6.76e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 6.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  984 EHLETENMSLRERIDSINKELEISKEKLHTLEQAFENISTTGGEIIMDKATKAVANseivsvsrRITTLEMKELNERQRA 1063
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQ--------QLSELESQLAEARAEL 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1064 EHAQKMYEHLRNSLKQVEERNFELETKfAELTKLNLEAQRIERELRDELADSVSKHIsdadrkRITELEKTEANLRIEVS 1143
Cdd:COG3206   236 AEAEARLAALRAQLGSGPDALPELLQS-PVIQQLRAQLAELEAELAELSARYTPNHP------DVIALRAQIAALRAQLQ 308

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 688616510 1144 K-LREVSDVAKMQVSALDARQQSREKEVESLRRQVLDYQAESDE 1186
Cdd:COG3206   309 QeAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAE 352
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1282-1383 7.00e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.77  E-value: 7.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1282 HLQEDRARVREDAQITEEERRKAEGKAQELELKLKGLEELIATLKD--AKGAQKVSEWHKKLEDVRL---LEMRQSRELN 1356
Cdd:COG2433   389 ELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAelEEKDERIERLERELSEARSeerREIRKDREIS 468

                          90       100
                  ....*....|....*....|....*..
gi 688616510 1357 TQREEIKYLKNCVAEQERTISGLEEEL 1383
Cdd:COG2433   469 RLDREIERLERELEEERERIEELKRKL 495
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 144-761 7.26e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.03  E-value: 7.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   144 ELALRAEEAEEKNrKLKREIKQLTRKNEQLQQDIEFYRKEAEQRESlQTKEESNEIQRRLT----KANQQLYQCMEELQH 219
Cdd:pfam15921  244 EDQLEALKSESQN-KIELLLQQHQDRIEQLISEHEVEITGLTEKAS-SARSQANSIQSQLEiiqeQARNQNSMYMRQLSD 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   220 AEDMAANLRSENEHLQKNLEESVKEMEKMtdeynkmkiaVQQTDAIMDQLRKDRDHAKLQVRELTDQIQARVEEDDPVMA 299
Cdd:pfam15921  322 LESTVSQLRSELREAKRMYEDKIEELEKQ----------LVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREK 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   300 AVNAKVEEWKSVLSGKDLEILEYQQMIRDLREKLRTAQmdsdksNIIALQQVIYELCGAVQERDN---QIKMLS-EQVEQ 375
Cdd:pfam15921  392 ELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQ------RLEALLKAMKSECQGQMERQMaaiQGKNESlEKVSS 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   376 YTTEMERNAMLIEELKRPLKKDKGHSSDHQRRLEDLSAKLQVAERKVlEAQRAAQLAERDARD-KDKELNDTLSRIRLYE 454
Cdd:pfam15921  466 LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAI-EATNAEITKLRSRVDlKLQELQHLKNEGDHLR 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   455 SGTDGLEAAISEIKECKNQIRVRDREIEGMIKEINQLEMKINNLLDENEDLRERLGlnpKEELDLSEFRRSKILKQRQYK 534
Cdd:pfam15921  545 NVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIN---DRRLELQEFKILKDKKDAKIR 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   535 AENQVLLKEIERLEEERLELKQRIRALvkdKGVTVVSNSLLDnsvEEKPVRSLRPSSGSTDDEIKR--KNERLQKELSNK 612
Cdd:pfam15921  622 ELEARVSDLELEKVKLVNAGSERLRAV---KDIKQERDQLLN---EVKTSRNELNSLSEDYEVLKRnfRNKSEEMETTTN 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   613 EKELELRRSEStqfkaKLNEMLNENKQLEQGMKEILQAIQDTQKKTPTSTGvSIPSLERLVNALE------------MKY 680
Cdd:pfam15921  696 KLKMQLKSAQS-----ELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRG-QIDALQSKIQFLEeamtnankekhfLKE 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510   681 SEGKFDASLH-LRTQVDQLTGRNEELRQEMKTAREEAANTLSQLTKANEKIARLESEMESMSKSTGSSIPHKTLALPEEM 759
Cdd:pfam15921  770 EKNKLSQELStVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849


                   ..
gi 688616510   760 TP 761
Cdd:pfam15921  850 GP 851
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 112-225 7.36e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.99  E-value: 7.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  112 DEIRQLESHLERKEKEVTQLEKEmgKERKSNEELA-LRAEEAEeknrkLKREIKQLTRKNEQLQQDIEFYRKEAEQREsl 190
Cdd:COG0542   411 EELDELERRLEQLEIEKEALKKE--QDEASFERLAeLRDELAE-----LEEELEALKARWEAEKELIEEIQELKEELE-- 481

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 688616510  191 QTKEESNEIQRRLTKANQQLYQCMEELQH---AEDMAA 225
Cdd:COG0542   482 QRYGKIPELEKELAELEEELAELAPLLREevtEEDIAE 519
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1745-1990 7.88e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 7.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1745 TSQAEQQIITNAAQKEEALNVQQIVDKQTKELRACVRDLNEELQLAKDGVRAAKARENSLKEDLETLNKDLQRSQksqnk 1824
Cdd:COG3883    11 PAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERR----- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1825 lqsekEALEEHLNELKKKiQRLSSGLQAQVESDGPTvDALQK--KIRKLEhELDRKSISEPADKRSTLKEDKSSKEevvr 1902
Cdd:COG3883    86 -----EELGERARALYRS-GGSVSYLDVLLGSESFS-DFLDRlsALSKIA-DADADLLEELKADKAELEAKKAELE---- 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1903 wEEGKKWQARVDKMRNVLKEKEREVDSQAKQLATMKELYSRLEQEKVSLQKKLKGRGVTADQVVGARTLEADKEIEELHK 1982
Cdd:COG3883   154 -AKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232


                  ....*...
gi 688616510 1983 RNAELEQQ 1990
Cdd:COG3883   233 AAAAAAAA 240
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 2058-2266 8.73e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.52  E-value: 8.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2058 DVIEAEQTQSSLLNSTVVVTEKEISVIEDKATQtsfrsidmgtAEVNQDDENVAKNKIDLEQKALMKDDKTEQEESNKEK 2137
Cdd:TIGR00927  634 DVAEAEHTGERTGEEGERPTEAEGENGEESGGE----------AEQEGETETKGENESEGEIPAERKGEQEGEGEIEAKE 703

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510  2138 GSVEKDEEQPDETQRGQDVAVFEYAQEELKTNDEAE----ELESELTHREMMEKPLDEDQLEVENE------------ET 2201
Cdd:TIGR00927  704 ADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEevedEGEGEAEGKHEVETEGDRKETEHEGEteaegkededegEI 783

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 688616510  2202 NAEEMlySTMNQAELETPKVLLEGDEDYGQEPEELLKCECDPSAESKELDEEETALSNSTTFDAK 2266
Cdd:TIGR00927  784 QAGED--GEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAK 846
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2365-2527 8.83e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 8.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2365 LEQANKDLPRLKDQVSDLKEMCSVLKKEKAEVE---------KRLNHLRGSGRSGKTIPE--LEKTIGLMKKVVEKVQRE 2433
Cdd:PRK05771   95 LEKIEKEIKELEEEISELENEIKELEQEIERLEpwgnfdldlSLLLGFKYVSVFVGTVPEdkLEELKLESDVENVEYIST 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2434 NENLKRTSEVNVQEQLATLERDHEKLksEYEKLKGKQEEQLNSRLESKTKGIEKIMMENERLRKEIKKEAEAAEKLRVAk 2513
Cdd:PRK05771  175 DKGYVYVVVVVLKELSDEVEEELKKL--GFERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLA- 251

                         170
                  ....*....|....
gi 688616510 2514 ASLEVANEKLKAEL 2527
Cdd:PRK05771  252 LYEYLEIELERAEA 265
PRK12704 PRK12704
phosphodiesterase; Provisional
 2422-2529 9.02e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 9.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 2422 LMKKVVEKVQRENENLKRTSEVNVQEQLATLERDHEKLKSEYEKLKGKQE--EQLNSRLESKTKGIEKIMMENERLRKEI 2499
Cdd:PRK12704   54 IKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLEllEKREEELEKKEKELEQKQQELEKKEEEL 133

                          90       100       110
                  ....*....|....*....|....*....|..
gi 688616510 2500 -KKEAEAAEKL-RVAKASLEVANEKLKAELEE 2529
Cdd:PRK12704  134 eELIEEQLQELeRISGLTAEEAKEILLEKVEE 165
PRK12704 PRK12704
phosphodiesterase; Provisional
 1295-1430 9.83e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 9.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688616510 1295 QITEEERRKAEGKAQELELKLKgleeliatlkdakgaqkvSEWHKKLEDVRllemrqsRELNTQREEIKYLKNCVAEQER 1374
Cdd:PRK12704   42 RILEEAKKEAEAIKKEALLEAK------------------EEIHKLRNEFE-------KELRERRNELQKLEKRLLQKEE 96

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 688616510 1375 TISGLEEELVQQNNLLEERQLIWDQREVQLERQLDSYEKQQNEVLntaQKFEEATG 1430
Cdd:PRK12704   97 NLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQL---QELERISG 149
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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